LOCUS       KC526903               30104 bp    DNA     linear   BCT 17-JUL-2019
DEFINITION  Acinetobacter baumannii strain LUH5550 KL42 capsule biosynthesis
            gene cluster, complete sequence.
ACCESSION   KC526903
VERSION     KC526903.1
KEYWORDS    .
SOURCE      Acinetobacter baumannii
  ORGANISM  Acinetobacter baumannii
            Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
            Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
            complex.
REFERENCE   1  (bases 1 to 30104)
  AUTHORS   Hu,D., Liu,B., Dijkshoorn,L., Wang,L. and Reeves,P.R.
  TITLE     Diversity in the major polysaccharide antigen of Acinetobacter
            baumannii assessed by DNA sequencing, and development of a
            molecular serotyping scheme
  JOURNAL   PLoS ONE 8 (7), E70329 (2013)
   PUBMED   23922982
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30104)
  AUTHORS   Senchenkova,S.N., Popova,A.V., Shashkov,A.S., Shneider,M.M.,
            Mei,Z., Arbatsky,N.P., Liu,B., Miroshnikov,K.A., Volozhantsev,N.V.
            and Knirel,Y.A.
  TITLE     Structure of a new pseudaminic acid-containing capsular
            polysaccharide of Acinetobacter baumannii LUH5550 having the KL42
            capsule biosynthesis locus
  JOURNAL   Carbohydr. Res. 407, 154-157 (2015)
   PUBMED   25776191
REFERENCE   3  (bases 1 to 30104)
  AUTHORS   Reeves,P.R., Hu,D., Liu,B., Zhang,Z. and Wang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JAN-2013) TEDA School of Biological Sciences and
            Biotechnology, Nankai University, 23 Hongda Street, TEDA, Tianjin
            300457, P.R. China
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: velvet v. 2.0
            Sequencing Technology :: Illumina; Sanger dideoxy sequencing
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..30104
                     /organism="Acinetobacter baumannii"
                     /mol_type="genomic DNA"
                     /strain="LUH5550"
                     /serotype="O22"
                     /db_xref="taxon:470"
                     /note="serogroup: PSgc22"
     gene            1..1542
                     /gene="mviN"
     CDS             1..1542
                     /gene="mviN"
                     /note="integral membrane protein MviN"
                     /codon_start=1
                     /transl_table=11
                     /product="MviN"
                     /protein_id="AHB32423.1"
                     /translation="MALWRSTFIVSAMTMLSRVLGLVRDVVLLNVFGAGKDFDTFVVA
                     FRIPNFFRRLFAEGAFSQAFIPVLTEYKTGRAHAEVQILISRVFGCLLTVMTLLTFVA
                     MVLAPAIIYMYAPGFHNDPEKFDLAVSMFRLTIPYLMFMSLTAFASSILNSYGSFASP
                     AFSPVLLNVAMIAGAWWLTPYMAEPIKALGWSVVAAGILQLAIQIPELWRKNLLIPPK
                     VDFKHEGVERILKLMLPALFGVSVTQINLLLNTIWASFMQDGSVSWLYSAERMTELPL
                     GLIGVAIGTVILPSLSARHAEQDQAKFRSMIDWAAKVIVLVGLPASIALFMLSTPIIQ
                     ALFQRGEFDLRDTQMTALALQCMSAGVISFMLIKVFAPGFYAQQDTKTPVRVGLMSVA
                     ANAILNVVFIGFFKLINWHAEHMALALASSGSALVNAGLLYFYLHKRNIFRFGAHWKK
                     LALQYGLANLAMIAALWFGLNWYNGELSQWIRVAEVVGLCVVGVIAYLIGLLLTGFRP
                     RDLKH"
     gene            complement(1588..2283)
                     /gene="fklB"
     CDS             complement(1588..2283)
                     /gene="fklB"
                     /note="FKBP-type 22KD peptidyl-prolyl cis-trans isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="FklB"
                     /protein_id="AHB32424.1"
                     /translation="MKKISLVIAASTMSLSVFAATPITNKSPAKDQFSYSYGYLMGRN
                     NTDALTDLNLDIFYQGLQEGAQNKTARLTDEEMAKAINDYKKTLEAKQLVEFQKQGQQ
                     NAQAGAAFLAENAKKSGVITTKSGLQYQVLKEGTGKTPKATSRVKVNYEGRLLDGTVF
                     DSSIARNHPVDFQLNQVIAGWTEGLQTMKEGGKTRFFIPAKLAYGEVGAGDSIGPNST
                     LIFDIELLQVLPK"
     gene            complement(2334..3056)
                     /gene="fkpA"
     CDS             complement(2334..3056)
                     /gene="fkpA"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="FkpA"
                     /protein_id="AHB32425.1"
                     /translation="MSKALPIAVAVVLGGAALVPVYYATQHPTTEVGRKADKNASPIQ
                     KISYVLGYEVAQQTPPELDTKAFVQGIHDARNKQPSAYTQEDLKAAIAAYEKELQQKM
                     QHQDKPEQAGTATDSADAQFLAENKTKAGVKTTVSGLQYIITKEGTGKQPTAQSVVKV
                     HYEGRLINGQVFDSSYKRGQPVEFPLNQVIPGWTEGLQLMKEGGKATFFIPSNLAYGP
                     QELPGIPANSTLIFDVELISVK"
     gene            complement(3247..5433)
                     /gene="wzc"
     CDS             complement(3247..5433)
                     /gene="wzc"
                     /note="protein tyrosine kinase; involved in capsule
                     export"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzc"
                     /protein_id="AHB32426.1"
                     /translation="MNQQNTNTEDTIDLKELFFSLIAQWKLIALCVILSVVCALLYLR
                     VTPDTYSVDALVQVEDSKGASAALLGDLSQMIEQKSPAQAEIEILKSRLVLGSVIKDL
                     HLDIQVSSTENTFTHRLLSDTDYKTEYAKKSVLFKDGLKSFDIRQFEIPAYYLDKNLL
                     LDFDKQSLRLTDPDTEEVILTVPLNQANSVTGPYGVWKVAIFTNDQFESTYNIKKLSL
                     PLAIKSISSDYSVEEKGKLTGILGLSYQGQDQEHITKVLNAILATYSAQNIERRSAES
                     AQTLKFLDEQLPDLKKQLDDAERQFNKFRQQYNTVDVTKESELYLTQSITLETKKAEL
                     EQKQAEMAAKYTAEHPAMREINGQLAAINKQIGELNSTLKQLPDVQRQYLQLYREVEV
                     KTQLYTALLNSYQQLRIAKAGEIGNVRIVDTAIEPVQPIKPKKLLVLILSVFVGGFLG
                     TLIALLRNMLRTGIKDSGQIENELDLPVYATVPRSPIQESRIKILKKKKSIPILAVKN
                     SDDIAIESLRSIRTAIHFALANAKNNIIMIAGPSPEVGKSFISTNLATIFAQGDKRVL
                     LIDADMRRGYMHKYFDVDVKPGLSELLSGQADLQKVLHKTQVANLDVITRGKSPTNPS
                     EILSSNQFKELLEQLQSQYDHIIIDTPPVLAVTDGIIISQYTGVNLIVARYAKSQMKE
                     LELTVNRFEQAGVKVNGFILNDIQRASSGYGYGYNYAYAYKAQKED"
     misc_feature    3247..26146
                     /note="KL42 capsule biosynthesis gene cluster"
     gene            complement(5453..5881)
                     /gene="wzb"
     CDS             complement(5453..5881)
                     /gene="wzb"
                     /note="low molecular weight protein tyrosine phosphatase;
                     involved in capsule export"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzb"
                     /protein_id="AHB32427.2"
                     /translation="MQIKNILVVCIGNICRSPMAEYFLKQQYPQLNIESAGISGLIGH
                     QADEKAQLCMQRLGIDMQSHIARKLNAELIKKADLILVMSNNQQKHIEQTWPFAKGKT
                     YRLGHWQNKNVPDPYQHEQAVFDETCQLIQQCVADWKPYI"
     gene            complement(5886..6986)
                     /gene="wza"
     CDS             complement(5886..6986)
                     /gene="wza"
                     /note="outer membrane protein; involved in capsule export"
                     /codon_start=1
                     /transl_table=11
                     /product="Wza"
                     /protein_id="AHB32428.1"
                     /translation="MKYCQFFSVLALSLSAASCAVTSGLQTYDIPSEGVYKTDLGTTV
                     NVIKISQETLPAIQPAQIDYQRDYASLFKNQQSIYRLSPGDVLSIQLWAYPEITPPVN
                     SISNEQSVQANGYPIDQSGYIQFPLVGRYKAAGKTLAQVNRELHNQLARFLKNPDVVV
                     RVVSYEGQRFSVQGSVTKGGQFYLNDQPVSIYTALGMAGGVTTTGDNTYIQLIRNGRT
                     YNLNTIDLEKAGYSLHKLLVQPNDTIYVSTRENQKIYVMGESGKNQALPMRDQGMTLT
                     DALGESLGINPLSGSASRIYVVRTNPNDRTTEIYHLNLMSIGDFGLANQFRLRSNDVV
                     YVDATGLTRWQRIINQIIPFSNALYNIDRLGQ"
     gene            7341..8615
                     /gene="gna"
     CDS             7341..8615
                     /gene="gna"
                     /note="UDP-N-acetyl-galactosamine dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gna"
                     /protein_id="AHB32429.1"
                     /translation="MQIAKLKIAIIGLGYVGLPLAVEFGKKVPVVGFDIYQKRIDELK
                     NGQDHTLEVSPDELKQAVHLNYTAHLDDLQDSNFFIVTVPTPIDDFKQPDLTPLIKAS
                     TSIGQVLKKGDVVVYESTVYPGATEEVCIPVLEKVSGLKFNQDFFAGYSPERINPGDK
                     QHRVTNILKITSGSTPEVADYIDEVYNLIIEAGTHKAPNIKVAEAAKVIENTQRDVNI
                     ALINELALIFNKLDIDTEDVLKAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQSIG
                     LHPEIILAARRLNDRMGEHVATQLIKEMVKQRIQVVGARILVMGLSFKENCPDIRNTK
                     IVDFIKALKEYDLDLDIYDPWVDDTEVQHEYGLAPIKELQQGLYDAIVIAVAHNQFKS
                     MSAHEFHALGKEKHVLYDLKYVLDKSETDIRL"
     gene            8662..9660
                     /gene="psaA"
     CDS             8662..9660
                     /gene="psaA"
                     /note="UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase
                     involved in the synthesis of a pseudaminic acid variant"
                     /codon_start=1
                     /transl_table=11
                     /product="PsaA"
                     /protein_id="AHB32430.2"
                     /translation="MLQGSTILVTGGTGSFGNTFVPMTLEKYNPKKIIIFSRDEMKQW
                     EMAKKFKDDKRVRFFIGDVRDKERLYRSLDGVDYVVHAAATKIVPTAEYNPFECIKTN
                     INGAMNLIDACIDKKVKGVVALSTDKASSPINLYGATKLASDKLFVAGNAYSGEHGTK
                     FSVVRYGNVMGSRGSVIPFFMSIKDKGVLPITDDRMTRFMISLEQGVELVWHAFEDMV
                     GGEIYVKKIPSMKVTDLAAVVAPEAKQEVIGIRPGEKLHEQMISVEDAYYTYEYPEHY
                     KILPVINDWAETQERIKDGKRVPEGFHYSSDNNTEWMSPEDLQQWLIENAEKVGNI"
     gene            9662..10822
                     /gene="psaB"
     CDS             9662..10822
                     /gene="psaB"
                     /note="C4-aminotransferase involved in the synthesis of a
                     pseudaminic acid variant"
                     /codon_start=1
                     /transl_table=11
                     /product="PsaB"
                     /protein_id="AHB32431.1"
                     /translation="MFIPYGKQNINQADVDAVVQVLQSDFLTQGPQVPLFEKSVAELV
                     GAKYAFAMNSATSALHVACLALGLKKGDVLWTSPITFVASANCALYCEADVDFVDIDP
                     DTYNLSVDALKEKLEIAKKNNKLPKIVVPVHLCGQPCDMEKIHALSKEYGFSVIEDAS
                     HAIGGKYKESYIGSNQYSDITIFSFHPVKIITTAEGGMALTNNEDLAKKIDLLRSHGV
                     TRNPEFMTKPSEGPWYYQQVELGYNYRMTELQAALGVTQLTRLETFVAKRHEIAKKYN
                     ELLKDLPLITPYQLPETYSGLHLYVIRLKLDELSKGRKEIFEILREKGIGVNVHYIPV
                     HTQPYYQQLGFKQGDFPEAEAYYEAAISLPMFPDLTDEQIQYIYQTLKEVLV"
     gene            10825..11514
                     /gene="psaC"
     CDS             10825..11514
                     /gene="psaC"
                     /note="cytidylyltransferase involved in the synthesis of a
                     pseudaminic acid variant"
                     /codon_start=1
                     /transl_table=11
                     /product="PsaC"
                     /protein_id="AHB32432.1"
                     /translation="MQLAVIPARGGSKRIPRKNIKDFYGKPMIVWSIEAALKSKCFDE
                     VWVSTDDQEIADIAVKFGAKVPFLRPAHLSDDYATTADVMQHAIQAFAQLRGQSPDFV
                     CCLYATAPFVQVDDLKTGLQLLQSHPLDYAFSATTFAFPIQRAIKLNKEGNVEMFQPE
                     NFNKRSQDLEEAWHDAGQFYWGTAQAWQEKYPVFSSKSRIVELPRTRVQDIDTLEDWQ
                     LAEMLFGALKL"
     gene            11511..12593
                     /gene="psaG"
     CDS             11511..12593
                     /gene="psaG"
                     /note="nucleotidase involved in the synthesis of a
                     pseudaminic acid variant"
                     /codon_start=1
                     /transl_table=11
                     /product="PsaG"
                     /protein_id="AHB32433.1"
                     /translation="MIMRIGFRVDAAKHIGTGHLQRCLTLANYLKAKGHQCIFYCRDY
                     GQAFYNLVLNAGFQLEIIGQKTIGSLPKSEKDWLGVSIEKDSEDFIEKIKEKTIDICI
                     VDHYALNVNWERIIRKHVSKLIVIDDLAREHECEILLDQNFFPYYKQRYDLTTPLTTI
                     KLLGPEYCLLKKEFSLFRSLRNQEQINSNKILINFGGVGNFTLLQKVISVINRVDKYD
                     YILITGMLEKEQFQYLESLVTDKSNIKIMQSSSNMAELMNSSSFAIGACGSTVWERFC
                     LGLNAALVQVADNQRILLGYLAEEDLIDNLGDCNDLTEDRLFEFLSKLDFTSVSYRQR
                     RIKIMELVDGLGVVRTCEKILELSNV"
     gene            12586..13485
                     /gene="psaH"
     CDS             12586..13485
                     /gene="psaH"
                     /note="N-acetyltransferase involved in the synthesis of a
                     pseudaminic acid variant"
                     /codon_start=1
                     /transl_table=11
                     /product="PsaH"
                     /protein_id="AHB32434.2"
                     /translation="MFKGKIRPVQLKDAEMILTWRNQDSVRMNMYNHDIIELDAHLKW
                     FNSILVNDTCRYFIYEQNNTPLGVLSFNDIDFKNKKASWAFYSGDTTVRGIGSEMEQL
                     ALDYAFNELNLNKLCCEVLEFNFAVVNFHRKFGFKMEGIKKQDYYRDGKFYDIYQLAL
                     FKKDYQKIQSQAYSPIEKSYVWSFSIPEEKIDQFATLSGDKNPVHLDKEAAISLGFEN
                     RIAHGALLVAEISKVAAMDYPSRNAIYLGQNLDFKAPIYPNVELTGKAKLKTQIGRYV
                     IIEYVVYQEEKLIAQGESEFLLS"
     gene            13512..14552
                     /gene="psaF"
     CDS             13512..14552
                     /gene="psaF"
                     /note="condensase involved in the synthesis of a
                     pseudaminic acid variant"
                     /codon_start=1
                     /transl_table=11
                     /product="PsaF"
                     /protein_id="AHB32435.2"
                     /translation="MQINHRNIGIQYPPYVIAELSANHNGHLETALKIIEEAKRCGAD
                     AVKLQTYSADTITLNSQNEEFMIRGGLWDGQSLYELYQKAQMPWEWHKPLFDHARALD
                     ITIFSSPFDRTAVDLLEDLNAPAYKIASFEAVDLPLIKYVASTGKPMIISTGMADKEE
                     IGEAIQAAYDGGCKELVVLHCVSGYPAPAEDYNLLTMVDMAKSFNVQVGLSDHTLDNT
                     TAIAAVTLGACVIEKHFTLDRNGGGPDDSFSLEPIELQHLCQSAKTAWQALGRVDYGR
                     KSSEQGNVKFRRSLYFVKDLKAGDVIDESSIRSVRPGFGLPPKFYDELIGKRVNQDIS
                     KNIATSFDCIDR"
     gene            14549..15802
                     /gene="wzx"
     CDS             14549..15802
                     /gene="wzx"
                     /note="oligosaccharide-unit translocase"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AHB32436.1"
                     /translation="MKKHFLSIFNLAVRGLNLASKFILIVFLAKFLTVAELGLYGLIA
                     ATINFAMYFIGLDFYVYSNRELLKSSDIQRNTIVSSHAQLLCFAYLFALPTLSIIFFK
                     DFLSLEYLIPFYGLIILEHLNQEFTRLLIVLKKPISSNLLLFVRSGGWSFIIIFLHFL
                     HVHLTLMDVLNIWIVAEILCFLLSIILLYREQVRLYLFQQVNWSWIWKGLKICLPFML
                     GTLAVRAIFTGDRYILEYFYDANILAAYVFFASLAAATMSFMDAAVFSFDYPELVRSI
                     NTRDNKHRELIKKLYKKVAFLLILINLSAYVFIDLLLRLIGKDIFNSYLNYFYLLMLV
                     QVLYAFSMIPHYILYALDADKPIIGTQISSLVIFLLFCFSLIGLLQEDYGIFVALLAS
                     FSFLFLSKYIYSWRLLKRYEHSYSS"
     gene            15780..17216
                     /gene="kpsS2"
     CDS             15780..17216
                     /gene="kpsS2"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="KpsS2"
                     /protein_id="AHB32437.1"
                     /translation="MNILILVNPAKNYKYFFYNVAKSLVDLGHSVYYAYDTEKNKILF
                     PIPEIDESSKSYFFDVFFKINQEENLQSNDEFLFDCTWGEYFYSDFDRFLTHGYNLEK
                     DAEEWVKIRKKMDSFFYKIITEKNIDLVLYENISNSFEYSAYRVAQTLGKKYFGLIAS
                     RIPGRYEIQTSIIDDLLVDLELVKEKPLTEEEINWYEDYKSNINKIEPDYMKQNGLDN
                     VSLLNKVSSNIFYKIIRSIKADIKYGAKSDYASGLLFLRILSAVKVAVNRRLNHKKTK
                     KYFLKMDEVNEIKQQHKFYVYPMHYHPESSTSVLAPQYTNEYHNILNISNNLPFGQYL
                     YVKDHRSAIGLNSDEFYRKISALPAVRLIPAEYNIKDLIKYSAGVITVNSTAGYEALI
                     LGKPVYLLGNVFYQNFSNVVRLENFNSLKSCLEKPTEFIENAADIVAYRRVTYEGILN
                     FNMIEYDSNKVFFDKLAMNIQENMLGKT"
     gene            17409..18242
                     /gene="wzy"
     CDS             17409..18242
                     /gene="wzy"
                     /note="oligosaccharide-unit polymerase"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AHB32438.2"
                     /translation="MLVYSEAMTYDWSFYKTFYTLREPVYWLSSKYLFELLHSNVLVF
                     IILDTIFLSALVFAGYKYKIKPYFILLFILFFPNLMGFLNIYRQFLATIALFICFFML
                     YHNLNGSRLIYLVSLFIHNVSIVFLPILFIKKTFFQFLFIVFSFISIALMVLFSGSKS
                     EVDTGEVSPFLFLAVICIIVTIFLFLNKLVLYRKNIDLYYINFYCVLVSAFSSLFLAG
                     APAKRICMIALSFLLYSIYWFIEDNRKNILLFRIILVVFSLIPTFIFSSAFLMLLNKT
                     T"
     gene            18315..19145
                     /gene="gtr5"
     CDS             18315..19145
                     /gene="gtr5"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AHB32439.1"
                     /translation="MFFSILLSLYHKEKSEYFDQCFESIWTRQILKPTEIVLVLDGPI
                     GNELTNSVQKWQSKIGDALKIIALPQNVGLGKALNEGLKHCTYEWVFRMDTDDICTAD
                     RFEKQAAFIQQHPDVVLFSGQVMEFDQDISDANVLKSVPVTHEEIKEFAQKRCPFNHM
                     TVAYKRDVILGLGGYQHHLFMEDYNLWLRVIGNNYKVANLADVLLYARVGNGMHSRRK
                     GFQYIKSEKQLLDLKKQLKLQNPLYANMLFLVRSAFRLLPANLLGKIYNTFLRKDIKK
                     "
     gene            19158..19778
                     /gene="itrA2"
     CDS             19158..19778
                     /gene="itrA2"
                     /note="initiating transferase for oligosaccharide
                     synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AHB32440.2"
                     /translation="MKRLVDIVISLIALTVLSPIFLIVAYKVRKNLGSPIFFYQERPG
                     KDGKLFKMIKFRSMKDAFDAQGNPLPDEARITPFGQKLRSTSLDEMPQLINVLKGDMS
                     VVGPRPMLKDFVALYSPEQARRLEVRPGMTGLAQVSGRNELDYEERFKCDVWYVDNHN
                     VWVDFKIMFKTVKVMLKREGINAPGHVGPSLFKGNDTQENIDSSVK"
     gene            19803..20678
                     /gene="galU"
     CDS             19803..20678
                     /gene="galU"
                     /note="UTP-glucose-1-phosphate uridylyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="GalU"
                     /protein_id="AHB32441.1"
                     /translation="MIKKAVLPVAGLGTRFLPASKSIPKEMVTVVDRPAIEYVVREAV
                     EAGIEQIILVTHSSKASIENYFDRNFELETTLEQKKKFDLLAEITQIVPEHVSVVSVR
                     QPQPLGLGHAVLCAKSVVGQDDFAVLLPDVLVKDSSGQNDLSRMISRYNSSQAAQIMV
                     EAVPDHLVDQYGIVDVKHSPNEGESIAMQGIVEKPAVGSAPSNLSVVGRYVLPAKIMQ
                     LLENTPKGAGNEIQLTDAIAMLQDTDTVEAYRMQGQTFDCGSKIGYLKAVLHYGIEHP
                     KLGNDFKQLIQELKL"
     gene            20794..22056
                     /gene="ugd"
     CDS             20794..22056
                     /gene="ugd"
                     /note="UDP-glucose 6-dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="Ugd"
                     /protein_id="AHB32442.1"
                     /translation="MKIAVFGTTLHAGVMAALLAEYGNQIYWCTSVTCEENISILSYQ
                     DQEVNHYLNKQRKAGFLKESPFSEIPLDIEVYLFCFSPTQIELALKTVEKLSERPIVH
                     PRLMINGSTFGLHGTNQLKQHLPKDEWVYFPDVIQEGNAINSVLNVKHVIVGVESSYA
                     QDTMQELLRPFFRFSYQYLFMPILDAEFTKLSISGMLATRISYMNDLAMVAEKLGIDI
                     ANVKHGIAADTRIGAAYLSAGVGFGGENFSHDILTLSSTVSGTGAKSRLLEQVWAINE
                     QQKEILFRKLWNYYHCDLSGKTVAIWGASFKENTSSTHNSPIHILLAALWAQGVKVRL
                     HDPQALDEIATTYGDREDLVLCADQYEAAQGAHALCLVTAWKQYWSPDFKQLQQVMQH
                     PLILDGRNIYDPAYVKAKGFAYEGVGRL"
     gene            22053..23723
                     /gene="gpi"
     CDS             22053..23723
                     /gene="gpi"
                     /note="glucose-6-phosphate isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gpi"
                     /protein_id="AHB32443.1"
                     /translation="MSKSIEKFPKELVSPIAQLHSLVEKNSKLHIKELFAAEQDRFQN
                     YSVKFDQLVFDYSKHRITKSVLEQLFALAKTKQLTHWIERLFSQDKVNCTEQRAAMHW
                     ALRLPSEYSKFPELTKQVHTQLQRMYVLVEKIHAGQYRGATGEVIQDVVNIGVGGSDL
                     GPQMVTHALCDFKVKTAKPLNVHFVSTMDGSQLSDLLHQLRPETTLFIISSKSFGTID
                     TLSNAQTVRQWLEKALGKHDRVVKSHFIGVSTKAEKMTEWGIAPENQLLLWDWVGGRY
                     SLWSCIGFPIALTIGIDGFQQLLAGAHAVDEHFQNTNFEQNIPVLMALLGIWNNNFLN
                     IQTHAVLPYDGRLKYFAAYLQQLEMESNGKSVQRDGQKVELDTCPIVWGEVGPNAQHA
                     FYQLLHQGTQAVSCDFIAPIQRYNADHFTYVENAEALIEQHHLALSNCLAQSRLLAFG
                     NEALDSAELKNLPIYKQYEGNQPSSTLLLKELNPYSLGMLIALYEHKVFVQSVIWNIN
                     PFDQWGVEKGKQIADQLLPILNGAQNDLSTLDASTRGLIKILLGKVDG"
     gene            23716..24732
                     /gene="gne1"
     CDS             23716..24732
                     /gene="gne1"
                     /note="UDP-glucose/UDP-N-acetyl-glucosamine 4-epimerase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gne1"
                     /protein_id="AHB32444.1"
                     /translation="MAKILVTGGAGYIGSHTCVELLEAGHEVIVFDNLSNSSKESLNR
                     VQEITQKSLTFVEGDIRNSGELDQVFQEHAIDAVIHFAGLKAVGESQEKPLIYFDNNI
                     AGSIQLVKSMEKAGVYTLVFSSSATVYDEANTSPLNEEMPTGMPSNNYGYTKLIVEQL
                     LQKLSVADSKWSIALLRYFNPVGAHKSGRIGEDPQGIPNNLMPYVTQVAVGRREKLSI
                     YGNDYDTIDGTGVRDYIHVVDLANAHLCALNNRLQAQGCRAWNIGTGNGSSVLQVKNT
                     FEQVNGVPVAFEFAPRRAGDVATSFADNARAVAELGWKPQYGLEDMLKDSWNWQKQNP
                     NGYN"
     gene            complement(24776..26146)
                     /gene="pgm"
     CDS             complement(24776..26146)
                     /gene="pgm"
                     /note="phosphoglucomutase/phosphomannomutase"
                     /codon_start=1
                     /transl_table=11
                     /product="Pgm"
                     /protein_id="AHB32445.1"
                     /translation="MTTLTCFKAYDIRGKLGTELNEEIAYKIGRAYGQIYKPKTVVVG
                     CDIRLSSEALKQATIRGLNDAGVNVLDLGMTGTEEVYFAAFHLDVQGGIEVTASHNPM
                     DYNGMKLVRENARPISADTGLKEIQALAETNNFEEVSQKGTTQSYNILPEFVDHLLTY
                     IEPAKIRPLKLVVNAGNGAAGHVIDAIEEKFKALNVPVEFIKIHHEADGTFPNGIPNP
                     ILIENRDSTRNAVLEHKADMGIAWDGDFDRCFLFDEKGQFIEGYYIVGLLAQAFLIKQ
                     SGEKIVHDPRLVWNTFDIVNEYKGVAVQSKSGHAFIKDVMREHNAVYGGEMSAHHYFR
                     DFAYCDSGMIPWLLTIALLSETGQSLSTLVENMIAKFPCSGEINFKVVDTQTTIQKIF
                     DFYADQNPQIDRTDGVSLDFGAWRFNVRASNTEPLLRLNIESRADRQAQPMQHYVDEL
                     TGLIQN"
     gene            26517..28184
                     /gene="lldP"
     CDS             26517..28184
                     /gene="lldP"
                     /note="L-lactate permease"
                     /codon_start=1
                     /transl_table=11
                     /product="LldP"
                     /protein_id="AHB32446.1"
                     /translation="MTMLNMWQQLYDPLNNIWLSSAVALIPIIFFFLALAVFRLKGSI
                     AGTGTVIIALLIALFFYQMPGQMAFASIIYGFFYGLWPISWIIIGAVFLYKISVKTGQ
                     FEVIRSSILSITEDQRLQMLLVGFAFGTFLEGAAGFGAPVAITAALLVGLGFKPLYAA
                     GLCLIVNTAPVAFGAMGIPIIVAGQVSGVDTMEISQMVGRQLPFLTIIVLFWIMAIMD
                     GWRGVKETWPAVLVGGGAFAIAQYLTSNFIGPELPDITAAIASLVSLTLLFRVWKPKH
                     IFRFEPEAGQTLTQQPTTVQRYSIGKIAKAWSPFAILTVMVTIWSVKPFKALFAKDGA
                     LEHWIFKLEVPYLHKLVEKMPPIVSEMKPYEAIYKFDWFSATGTAIFIAAIITVIFLK
                     MKASEAVTTFGETLNELKTPIYSIGMVLAFAFIANYSGLSATLALALSHTGHAFTFFS
                     PFLGWLGVFLTGSDTSSNALFSALQATTAQQIGIPEVLLVAANTSGGVTGKMISPQSI
                     AIACAAVGLVGKESDLFRFTVKHSIIFTVFVGIIITVQAYLVPWMIP"
     gene            28204..28956
                     /gene="lldR"
     CDS             28204..28956
                     /gene="lldR"
                     /note="DNA-binding transcriptional repressor LldR"
                     /codon_start=1
                     /transl_table=11
                     /product="LldR"
                     /protein_id="AHB32447.2"
                     /translation="MRISDQVVMKLQALIEERHMKKGDRLPAERQLATSLGVSRPSLR
                     EAIQQLNSQGVLISRRGDGTYIQQLPEQWPQQLIVNPISNLIEEDPLYRFDVQEARLV
                     LEGGTAWYAALRSTPEDRAKIHHYFNEISRHQNAGDSAQAAVADAEFHLAIAEASHNV
                     VLIQMMRSLFDLLQYNVLLGRKKVYNDPVNGDLLSEQHFQVMDAIDRKDPEAARQAVC
                     GHIEFVINHVRSLDEDEARQKRANRLNRVDSK"
     gene            28953..30104
                     /gene="lldD"
     CDS             28953..30104
                     /gene="lldD"
                     /note="L-lactate dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="LldD"
                     /protein_id="AHB32448.1"
                     /translation="MIISSGNDYRAAAQRRLPPFLFHYIDGGAYAEYTLKRNVQDLSE
                     IALRQRVLNDMSALSLETKLFNETLSMPVALAPVGLTGMYARRGEVQAAMAADKKGIP
                     FTLSTVSVCPIEEVAPAINRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPV
                     PGARYRDAHSGMSGPNAAMRRYMQSVFHPHWSWNVGLMGRPHDLGNISKYLGKPTGLE
                     DYIGWLGSNFDPSISWKDLEWIREFWDGPMVIKGILDPEDAKDAVRFGADGIVVSNHG
                     GRQLDGVMSSARALPAIADAVKGDLAILADSGIRNGLDVVRMLALGADTVLLGRAFVY
                     ALAAAGGQGVSNLLDLIDKEMRVAMTLTGAKSISDINADCLVQAIKQGL"
BASE COUNT     9024 a   4998 c   6153 g   9929 t
ORIGIN
        1 atggcattat ggcgatcgac ttttattgtc agtgcgatga cgatgttgtc acgggtattg
       61 ggcttagtac gagatgtcgt attgctcaac gtgtttggtg cgggtaaaga ttttgatacc
      121 ttcgttgtgg cttttcgtat tcccaacttc tttcgacggt tgtttgccga aggggctttt
      181 tcacaggctt ttattccggt attgaccgaa tataaaacag gtcgtgcgca tgcagaagtg
      241 cagatcttaa ttagtcgagt atttggctgt ttgctgacag tcatgacttt actgactttc
      301 gtggctatgg ttttagctcc agcaattatc tatatgtatg cgccgggttt ccataatgac
      361 cctgaaaagt ttgatttagc ggtcagtatg ttccgtctga ccattccata tttaatgttt
      421 atgtcgctta cagcttttgc cagcagcatc ttaaacagtt atggctcgtt tgcctcgcca
      481 gctttttcac ctgttttact gaacgtagca atgattgcag gagcgtggtg gcttacaccg
      541 tatatggctg agccaatcaa agctttaggt tggtcagttg ttgcggctgg tattttacag
      601 ttagctatac aaattcctga gttatggcgt aaaaacttac tgatcccacc aaaagttgat
      661 tttaaacatg aaggcgttga gcgtatttta aaattaatgc ttccagcatt atttggtgtc
      721 tctgtgactc agattaacct attgctaaat acgatttggg catctttcat gcaagatggt
      781 tcagtgtctt ggctctatag tgccgaacgt atgaccgagt tacctttagg tttaatcggt
      841 gttgcgattg gtacagtgat tttgccttca ctgtcagcac gtcatgctga acaagaccaa
      901 gcgaagtttc gtagcatgat cgattgggca gcaaaagtga ttgtattggt ggggttacca
      961 gcaagtattg ctttatttat gctttctaca ccgattattc aggcattgtt ccaacgtggt
     1021 gagtttgatt tacgcgatac acaaatgaca gcacttgcat tgcaatgtat gagtgcaggc
     1081 gtaatttcct ttatgttaat taaagtattt gcaccaggtt tctatgcgca gcaagatacc
     1141 aaaacgccag tccgtgtggg tttaatgtcg gttgcagcta atgcgatttt aaacgttgta
     1201 tttattggat tttttaaact aatcaattgg catgcagagc atatggcgct tgcattagcc
     1261 tcttctggtt cagctttagt aaatgcaggt ttgctctatt tttatctgca taagcgtaat
     1321 attttccgat ttggtgcaca ttggaaaaaa ctggcacttc aatatggttt ggctaacctt
     1381 gcgatgattg cagcactttg gttcgggtta aattggtata acggtgaact ctctcaatgg
     1441 attcgtgttg cagaggtagt cggtttatgc gttgtaggtg tgatcgctta cttaattggc
     1501 ttattactga caggctttag accgagagat ttaaaacact aaaataaaaa agcgatcaat
     1561 ttagatcgct ttttttatct tcgaaaatta ttttggcaaa acttgtagca actcaatatc
     1621 aaaaattaaa gtactatttg gaccgatact atccccagcg ccaacttcac cataagcaag
     1681 ttttgctgga atgaagaaac gggttttacc gccctctttc atagtttgta agccttcggt
     1741 ccatccagcg atcacttgat ttaactggaa atcaacaggg tgattacgtg caattgagct
     1801 atcaaataca gttccgtcga gtaaacgtcc ttcatagttt acttttacac gagaggtggc
     1861 tttaggtgtt ttaccagtgc cttcttttaa tacctgatat tgcagacctg atttagtcgt
     1921 aatcacacca gattttttag cattttctgc cagaaaagct gcaccagcct gagcgttttg
     1981 ttgaccttgt ttttgaaatt cgactagctg tttagcttct aatgtttttt tataatcatt
     2041 aattgctttc gccatttctt catcagttag gcgtgctgtc ttattttgag caccttcttg
     2101 taaaccttgg taaaaaatat caagatttaa atctgttaac gcatcagtat tattacggcc
     2161 cattaaataa ccataactat aactaaactg atcttttgcc gggcttttat ttgttatcgg
     2221 tgtagcagca aaaacagata aactcattgt tgatgctgca ataaccaaac tgattttttt
     2281 catgtcattt tccaaaaaaa acaggagagt ataacgactc tcctggattg ttattatttc
     2341 actgaaatga gttctacatc aaaaatcagt gtactgtttg ctggaattcc aggaagctct
     2401 tgtgggccat atgcaagatt tgatggtatg aagaaagtcg cttttccacc ttctttcatg
     2461 agttgaagac cttcagtcca acccggaatg acctggttaa gcgggaattc tactggttga
     2521 ccacgcttat aagaactatc gaaaacctgt ccattaatta agcgaccttc ataatgtact
     2581 tttacaacag actgagcagt tggctgttta ccagtacctt ctttagtaat gatatattgc
     2641 aaacctgata cagtagtttt tacgccagct ttcgttttgt tttctgcaag gaactgtgca
     2701 tctgcagagt cagtagctgt acccgcttgc tcaggtttgt cttgatgctg cattttttgt
     2761 tgtaactctt tttcataagc agcaatggca gcttttaaat cttcttgagt ataagcacta
     2821 ggctgcttat tacgcgcatc atggatccct tgaacaaatg ctttggtatc cagctcagga
     2881 ggggtttgct gagcaacttc atacccaaga acataactga ttttttgaat tggagaagca
     2941 tttttgtctg ctttacgtcc gacttctgtg gtcggatgtt gagttgcata atatacaggt
     3001 acaagtgcag caccgcctaa aactacagcg acagcaatgg gtaaggcttt actcataaaa
     3061 ggttccaaaa ataatcattt gagtctaaaa ggctgcttcg atcttagcat gcttcgactt
     3121 aagcatagaa tgtttaacaa aaaaaacgag tggtttttta tatattttag ttagttttaa
     3181 tgtggcaaaa cttaaaaagc aaataaaaaa ccggatcatt tgatccggtt ttatgaagag
     3241 ttttaattag tcttcttttt gtgccttata ggcataagca tagttataac cataaccata
     3301 gccagagcta gcacgttgaa tatcattgag aataaagccg ttaactttaa cacccgcctg
     3361 ttcaaaacga ttaacagtta gttcaagctc tttcatttgt gacttggcgt agcgtgcaac
     3421 aattaagttc acaccagtat attgtgaaat aataatacca tcggttaccg caagtactgg
     3481 tggagtatca ataatgatgt ggtcatattg gctttgtagt tgttcaagta attctttaaa
     3541 ctgatttgag cttaaaatct ctgaaggatt tgttggactc ttaccacgag tgatcacatc
     3601 aagattggct acctgagttt tgtgcaatac tttttgtaaa tcagcttgtc cacttaacaa
     3661 ttctgataga cctggtttca catcaacatc gaaatattta tgcatataac cacgacgcat
     3721 atcggcatcg atcaataata ctcgtttatc gccttgggca aaaatagtcg ccaagttagt
     3781 tgaaataaac gatttaccta cctcaggaga agggcctgca atcataatga tattattttt
     3841 tgcatttgct aatgcaaagt gaatagctgt acggatacta cgtaagctct caatggcaat
     3901 atcatcactg tttttaaccg caagaatagg aatactcttc ttcttcttta aaatcttgat
     3961 gcggctttct tgaattggag aacgaggaac agttgcataa accggtaaat ccaattcatt
     4021 ttcaatctgt ccagaatctt taatacctgt acgtaacata ttacgtaata aggcaatcaa
     4081 tgttccaaga aaaccaccca caaatacaga taaaataagg actaatagtt tctttggttt
     4141 aataggctga acaggttcga tagccgtatc gacaatgcgt acattgccaa tttcgccggc
     4201 tttggcaata cgaagttgct gatatgaatt taaaagagct gtataaagct gtgttttaac
     4261 ttcaacttca cgataaagct gtaaatactg gcgttgaaca tcgggtaatt gttttaaagt
     4321 actattgagc tcaccaattt gcttattaat cgcagcgagc tggccattaa tttctctcat
     4381 tgccggatgt tcagccgtat attttgctgc catttcagct tgtttctgct caagctctgc
     4441 ttttttagtt tccaaagtaa tactttgagt taaatatagc tcagattctt tagtcacatc
     4501 aacggtatta tactgttgac ggaatttatt aaattgacgc tcagcatcat ctagctgttt
     4561 tttcaggtca ggtagctgtt catctaaaaa ttttaaggtc tgagcagatt ctgccgaacg
     4621 gcgctcaata ttttgtgcac tataggtcgc taaaatagca tttaagactt tagtaatatg
     4681 ttcttgatct tgcccttgat agctaagtcc taatatacct gtgagtttac ctttttcttc
     4741 tacagaatag tcggaactga tagattttat agctaaagga agtgataatt tcttaatatt
     4801 ataagttgat tcaaattggt cgtttgtaaa tatagcaact ttccatacac catacggtcc
     4861 tgtaacgctg ttagcttggt ttaatggaac agttaagatg acttcttcag tatctggatc
     4921 tgttaaacgt aaagactgtt tatcaaaatc aagaagtaag ttcttatcta gataataagc
     4981 tggaatctca aactgacgta tatcaaaact ttttaaacca tctttaaata aaaccgattt
     5041 tttagcatat tcagttttgt aatcagtatc actcaataag cgatgtgtaa atgtattttc
     5101 agtgctagag acctgtatat ccagatgtaa atctttaata acagaaccta aaactaaacg
     5161 agattttaaa atttctattt ctgcttgagc tggtgatttt tgctcgatca tttgtgatag
     5221 atcgcctaaa agtgcagcag aagctccctt gctgtcctca acctgaacta aagcatctac
     5281 cgaataggta tctggtgtta cacgtaaata gagtagtgca catacaacac ttaaaataac
     5341 gcatagagca atgagtttcc actgtgcaat cagtgaaaaa aacaattctt ttaagtcaat
     5401 tgtatcttcg gtattagtat tctgttggtt catatgctta aaaatctata cgttaaatat
     5461 aaggtttcca gtcagccacg cattgctgaa tgagctggca agtttcatca aagacagctt
     5521 gctcatgctg gtaaggatcg ggcacatttt tattttgcca gtggcctaag cgataggttt
     5581 tacctttcgc aaagggccaa gtttgctcaa tatgcttttg ttggttatta ctcatcacta
     5641 aaataagatc agcttttttg atgagttcgg cattgagttt tcttgcaata tgggattgca
     5701 tatcaatgcc taaacgctgc atacagagtt gtgccttttc atcagcctga tgcccaatca
     5761 accccgaaat acccgcagat tcaatattga gttgaggata ttgctgtttt aaaaaatatt
     5821 ctgccatagg actacggcag atatttccaa tacagacgac taaaatattt ttaatttgca
     5881 taaaattatt gtcccaaacg gtctatgtta tataaagcat ttgagaaagg aataatttgg
     5941 ttgataatac gttgccaacg tgtcaagcca gttgcatcaa cataaacgac atcattacta
     6001 cgtagtctaa attgattcgc taaaccaaaa tcaccaatac tcattaaatt taaatgataa
     6061 atttcggttg tgcggtcatt cgggttagtc cgtactacat agatacggct agcacttcca
     6121 gataaaggat ttattcctaa actttcacct agggcatcag tcagtgtcat gccttgatca
     6181 cgcattggta acgcttggtt tttacctgac tcacccatca cataaatttt ttggttctca
     6241 cgtgtgctta cataaatagt atcgtttggc tgaaccagaa gtttatgaag tgaatagcca
     6301 gccttttcta aatcaatcgt atttaggtta taagttcggc cattccgaat cagttgaata
     6361 taagtgttat cacccgttgt agttacacca cctgccatac ccaaggcagt ataaatactg
     6421 acaggttggt cgtttaaata aaattgacca cctttagtaa cactaccttg aacagagaaa
     6481 cgttgtcctt cataagacac tacgcgcact accacatccg gattttttaa aaagcgagcc
     6541 agttggttat gtagctcacg gttgacttga gcaagtgttt taccagctgc tttgtagcgt
     6601 ccaaccaacg gaaactgaat ataaccactc tgatcgattg ggtaaccatt cgcttgaaca
     6661 gattgctcat tactaatgct attgactgga ggagtaattt ccgggtaagc ccacagctga
     6721 atagagagaa catcgcctgg acttaaacga taaatagatt gttggttttt aaataaggaa
     6781 gcgtagtcac gttgatagtc aatttgagct ggttgtattg ccggtaatgt ttcttgagaa
     6841 attttaatga cattaaccgt agttccgagg tctgttttat aaactccctc actcggaata
     6901 tcataagttt gtaaaccgga agtaaccgcg cagctggcag cacttaaact taaggcaaga
     6961 acagagaaaa actggcaata cttcacacgc gaccctttgt gtatttatct ttaattgata
     7021 ttgtccactg catagcgaca agtgtctatt aaacgcaggc tgaactgatt ctagctgaaa
     7081 agaaatgaaa aaacatagaa aaatcgcaag gctttgtatg tttagtttat ctggaacggg
     7141 cttttaagca gtggtcacag tgcagaaata ttaataatgt ataattttgg ctacattaaa
     7201 aaggtagctt ataaacgttg taaacacatt tatacaattg acgtacggcg ctgaatgaaa
     7261 atctgatata gtacgctgca ctgttagtgc caaaagcatg atttattaga tataaactct
     7321 aaggaaaaag gctcgtttat atgcaaattg ccaaattaaa aatagcaatt attgggttag
     7381 gctatgttgg cttgccgttg gcagttgagt ttggaaaaaa ggtaccagtt gtcggctttg
     7441 atatttatca aaaacgtata gatgagctta agaatggcca agatcatacc ttagaagttt
     7501 cacctgatga attaaagcaa gctgttcacc tcaactatac tgctcattta gatgatttac
     7561 aggactctaa ttttttcata gtcacagtgc ctacaccaat tgatgacttt aagcagcccg
     7621 atttaactcc tttaattaaa gcctcgacga gtattggaca ggttttaaaa aaaggtgatg
     7681 tagtggtata tgagtccacc gtatatccag gcgcaacaga agaggtatgt attccggttt
     7741 tggaaaaagt atctggactc aagtttaatc aagatttctt tgcaggttat agtccagagc
     7801 gcattaaccc cggtgataag cagcaccgtg taactaatat tttaaaaatc acatcgggtt
     7861 ccacacctga ggtcgctgat tatattgatg aagtttataa tttaattatt gaggcaggca
     7921 ctcataaggc cccgaatata aaagtagcag aagcggctaa agtaatcgaa aacacacaac
     7981 gtgatgtcaa tattgctctg attaatgaat tggctcttat ttttaataaa ctagatattg
     8041 ataccgaaga tgtactcaag gctgctggca ctaaatggaa ctttctacca ttccgacctg
     8101 gattggttgg ggggcattgt ataggtgtag atccctatta ccttacacat aaagcccagt
     8161 ctatcggctt gcatcccgaa attattttag cagctcggcg cttaaatgat cgtatgggtg
     8221 agcatgtggc gactcagctc attaaagaga tggttaaaca gcgaattcag gtcgttggtg
     8281 cccgtatttt agtaatgggt cttagtttta aagaaaattg ccctgatatt cgtaatacaa
     8341 aaattgttga ttttattaaa gcgttgaaag agtacgattt agatttagat atctatgacc
     8401 cgtgggtaga tgatacagaa gtacaacacg aatatggttt agcgccaatt aaagaattac
     8461 aacaaggctt gtatgatgcg atcgttattg ccgttgccca taatcagttt aaatcaatga
     8521 gtgcacatga gtttcatgca ttaggtaaag aaaagcatgt actttatgat ttgaagtatg
     8581 ttttagataa atcagagacc gatatcagac tttgatatta tttaggctaa taattttaat
     8641 ttgtttaaaa atgaggaaga gatgttacaa ggctcaacaa tattagtaac tggtggaaca
     8701 ggttcttttg gtaatacatt tgttccaatg acattggaaa aatataatcc taaaaaaata
     8761 attatctttt ctcgcgatga aatgaaacaa tgggaaatgg cgaagaaatt taaagatgat
     8821 aaacgtgttc gctttttcat tggtgatgtg cgtgataaag agcgcttata tcgttcttta
     8881 gatggggttg attatgttgt gcatgctgca gcaacaaaaa ttgtaccaac tgctgaatac
     8941 aacccttttg aatgtatcaa gaccaatatt aatggtgcaa tgaacttgat tgatgcatgt
     9001 atcgataaaa aggtaaaagg tgttgttgcc ctttcaacag ataaggcaag cagtccaatt
     9061 aatttatatg gtgcaacaaa acttgcatct gacaaattat ttgttgctgg taatgcatac
     9121 tctggtgaac atggtacaaa attctctgtt gtacgttacg gtaacgtaat gggatctcgt
     9181 gggtcagtta ttcctttctt tatgtcaatt aaagataaag gtgtgctacc aattacagat
     9241 gatcgtatga ctcgctttat gatctcgtta gaacaaggtg tagagcttgt ttggcatgca
     9301 tttgaagata tggttggtgg tgaaatttat gtgaaaaaaa ttccatcaat gaaagtgact
     9361 gatcttgctg cagtggttgc tcctgaagct aaacaagaag ttataggtat tcgtccaggc
     9421 gaaaaattac atgagcaaat gatcagtgtt gaagacgctt attatactta tgaatatcca
     9481 gagcattata aaatcctgcc tgtaatcaat gattgggcgg aaacacaaga acgtattaaa
     9541 gacggtaaac gagttccaga aggtttccac tattctagtg ataataatac tgaatggatg
     9601 agtccagaag atttacaaca atggttaatt gaaaacgctg agaaagtagg aaatatctaa
     9661 catgtttatc ccatatggca aacaaaatat aaatcaggct gatgttgatg cagtggttca
     9721 agttctccaa tctgactttt tgacacaagg tcctcaagtt cctttatttg aaaaatcagt
     9781 agcagaatta gttggggcaa aatatgcctt tgctatgaat agtgcaacat cagctttaca
     9841 tgtagcttgt ttggcattgg gattgaaaaa aggagatgtc ctttggacat ctccgattac
     9901 ttttgttgca tcggctaatt gtgcattgta ctgtgaagca gatgtcgact tcgttgatat
     9961 tgacccagat acctataatc tttcagttga tgctctaaaa gaaaaattag aaattgctaa
    10021 gaaaaataat aaattaccaa aaattgtagt gcctgtgcat ttatgtgggc agccatgtga
    10081 tatggaaaaa atccatgcac tttcaaaaga atatggtttt agtgttattg aagacgcatc
    10141 ccatgcaatt ggtggtaaat ataaagaaag ttatattggt tctaaccagt attccgatat
    10201 tacaatcttt agttttcacc cagtcaaaat tattacaacg gctgaaggtg gaatggcgct
    10261 taccaataat gaagatttag ctaagaaaat cgatttattg cgtagccatg gtgttacaag
    10321 aaacccggaa tttatgacca aaccatctga aggcccttgg tactaccaac aggttgagtt
    10381 aggttataac tatcgcatga ccgagttaca agctgcatta ggggttacac agttgactcg
    10441 cttagaaaca tttgtagcta aacgacatga gattgctaaa aaatataatg agcttttaaa
    10501 agatttacca ttaattactc cataccaatt accggaaaca tattctggtt tgcacttata
    10561 tgtcattcgt ttgaagctag atgaattgag taaagggcgt aaagaaattt ttgagatatt
    10621 gagagaaaag ggtattggag taaatgtgca ttatattcca gtgcataccc aaccttatta
    10681 tcaacaatta ggcttcaaac aaggcgattt ccctgaagca gaagcttatt atgaagctgc
    10741 tattagctta ccaatgttcc ctgatttgac tgatgagcaa attcagtaca tttaccagac
    10801 actaaaagag gtgttggtat aagaatgcaa ctggcggtta ttcctgcacg aggtggaagc
    10861 aaaagaattc ctcgtaaaaa cattaaagac ttctacggta agcccatgat tgtatggtct
    10921 atagaagcag cactgaaaag taaatgtttt gatgaggtct gggtctcgac tgatgatcaa
    10981 gaaattgcag atattgcagt taagtttgga gcgaaagttc cattcctgcg accagctcat
    11041 ttgtctgatg attatgcaac tacagcagat gtcatgcagc atgcgataca agcttttgca
    11101 caattacggg gtcaatcgcc agactttgtt tgctgtttat atgcgacagc accgtttgta
    11161 caggttgatg atctgaaaac tgggttacag ctattacaat ctcacccact agattatgct
    11221 tttagtgcaa cgacttttgc tttcccgatt caaagagcta ttaaattgaa taaggagggt
    11281 aatgttgaaa tgttccaacc agaaaacttt aataagcgtt ctcaggattt agaagaagcg
    11341 tggcatgacg cggggcagtt ctactgggga acggcacagg catggcagga aaaatatcca
    11401 gttttctcaa gcaagtctcg aattgtcgag ctccctagaa cacgtgtgca ggatattgat
    11461 accctagagg attggcaatt agcagagatg ttatttgggg ctttgaaatt atgataatgc
    11521 ggataggctt tagagttgat gctgctaaac atattggaac tggtcaccta cagcgctgtt
    11581 taactcttgc taattattta aaggcaaagg ggcatcaatg tattttctat tgtagagact
    11641 atgggcaagc tttttataat ttagtattga atgcaggctt ccaacttgaa attataggtc
    11701 aaaaaacaat tggcagtttg ccaaagtcgg aaaaagactg gttaggcgta agtatagaaa
    11761 aagatagtga agactttatt gaaaaaataa aagagaaaac aatagatatc tgtatcgttg
    11821 atcattatgc attaaatgtt aattgggaac ggattattcg gaagcatgtt tcgaagttaa
    11881 ttgttataga cgatttagct cgtgaacatg aatgtgaaat tctattagat caaaactttt
    11941 tcccatatta taagcagcgc tatgatctta caacgccatt aacaactatt aagttgttgg
    12001 ggccggaata ctgccttctt aagaaagagt ttagtctgtt tagatcattg agaaatcaag
    12061 aacaaattaa tagtaataag attttgatta actttggtgg tgtaggtaat tttacacttt
    12121 tgcaaaaagt tatatctgta attaatcgtg tggataagta tgattatatt ttaattacgg
    12181 gaatgttgga gaaagagcaa tttcagtatt tagagagttt agttactgat aaatcaaata
    12241 tcaaaattat gcaatcatca tcaaatatgg ctgaattaat gaatagttca agctttgcta
    12301 taggggcttg tggttcaacg gtttgggagc gtttttgttt agggttaaat gcagcgttag
    12361 tacaggtagc agataaccag cgtatcttat taggatattt ggctgaggaa gatttaattg
    12421 ataatttagg cgattgtaac gatttaacag aagatcgatt attcgaattt ttaagtaaat
    12481 tagatttcac cagtgtttct taccgtcaaa gaagaatcaa aataatggaa cttgttgatg
    12541 ggcttggtgt tgtcagaaca tgtgaaaaaa tcttggagtt aagtaatgtt taaaggaaaa
    12601 ataagaccag tccaactgaa agacgcagaa atgattttaa catggcgtaa tcaagattct
    12661 gtccgtatga atatgtataa ccatgatatt attgaattag atgctcatct gaagtggttt
    12721 aattctattt tggtaaatga tacttgtcgt tattttattt atgaacaaaa taatacacca
    12781 ttaggtgtgc tctcctttaa tgatatcgat ttcaaaaata agaaagcatc ttgggctttt
    12841 tactctggag ataccacggt acgaggtatt ggttctgaga tggagcaact ggcattagat
    12901 tatgctttta atgaattaaa tttaaataaa ttatgttgtg aagttttaga gtttaatttt
    12961 gctgttgtta atttccatcg caaatttggt tttaaaatgg aaggcattaa gaagcaggat
    13021 tactatagag acggtaaatt ctatgatatc tatcagttag ctctgttcaa aaaagattat
    13081 caaaaaatac agtcgcaagc ttatagccca atagaaaaaa gctatgtatg gagtttttct
    13141 attccagagg aaaaaattga tcagtttgct accttgtctg gcgataaaaa tcctgttcat
    13201 ttggataaag aggctgcgat ttcactgggt tttgaaaata gaatcgcgca tggcgcttta
    13261 cttgttgctg agatatcaaa agttgcagct atggactatc caagtagaaa tgcaatttat
    13321 ttaggacaaa accttgattt taaagccccg atttatccaa atgtagagct taccggaaag
    13381 gcgaagttaa aaacacaaat aggacgttat gtcattattg agtatgtcgt ttatcaggaa
    13441 gaaaaactta tagctcaagg cgaatccgag tttttattaa gctagtatta tccataagat
    13501 aggtgaagta aatgcaaata aatcatagaa atattggtat acagtatcca ccttatgtga
    13561 tagctgagct ctctgcaaac cataatgggc atttggaaac tgcacttaaa attattgaag
    13621 aagctaagcg ctgtggtgca gatgctgtta agttacaaac ttacagtgcg gatactatta
    13681 cattaaacag ccaaaacgaa gaatttatga ttcgtggtgg tttatgggat gggcaatctc
    13741 tatatgagct ctatcaaaaa gcacaaatgc catgggagtg gcataaaccg ctttttgacc
    13801 acgcgcgcgc tttagatatt acgattttta gctcaccatt tgatcggact gcagttgatt
    13861 tacttgaaga ccttaatgca ccagcatata aaattgcctc ttttgaagcg gtcgatttgc
    13921 cattaattaa atatgtagct tcaaccggca aaccaatgat tatttcaaca ggtatggcgg
    13981 acaaagaaga aattggtgaa gcaattcaag ctgcttatga cggtggttgc aaagagcttg
    14041 tagttttgca ttgtgtaagt ggttaccctg ctccagcgga agattataat ttgctaacca
    14101 tggttgatat ggcaaaatct tttaatgttc aagtaggatt atctgatcat accttagata
    14161 atacaacagc aattgcagcg gttacattag gtgcatgtgt tattgaaaaa cattttacac
    14221 tcgaccgcaa tggtggcgga ccagacgata gtttctcttt ggaacccata gaattacaac
    14281 acttgtgtca atctgcaaaa actgcatggc aggcacttgg tcgtgtagac tacggcagaa
    14341 aatcaagtga acaaggtaat gttaaattta gacgttcact ttactttgta aaagacttaa
    14401 aagcaggtga tgtgattgac gaatcaagta tccgtagtgt acgcccaggg ttcgggttac
    14461 cacctaaatt ttatgatgag cttataggaa aaagagtcaa tcaagatatt tcaaaaaata
    14521 tagctacaag ttttgattgt attgatagat gaaaaaacat ttcttatcca tatttaattt
    14581 agcagtacga gggttaaatt tagccagtaa atttatttta attgtttttc tggctaaatt
    14641 tctaacggtt gcagagctag ggttatatgg gctgattgct gcgacaatta attttgcaat
    14701 gtattttatc gggcttgatt tttatgttta cagcaatcgg gaattactga aaagctcaga
    14761 tattcaaaga aatacaattg tgagtagtca tgcacaacta ttatgttttg cttatctatt
    14821 tgctttacct actttgtcta ttattttctt taaagatttt ttatcactgg aataccttat
    14881 tccattttat gggttaatta tactagagca tttaaatcaa gagtttacac gtttgttaat
    14941 tgtgttgaaa aaaccaatta gttctaattt gttactattt gtacgttctg gtggttggag
    15001 ttttattata atttttctgc attttttgca tgtccattta accttaatgg atgttttgaa
    15061 tatctggata gttgctgaaa tattatgttt cttattgagc ataattctac tttatcgaga
    15121 gcaggttcgt ctttatctat ttcaacaagt gaattggagt tggatctgga aggggctaaa
    15181 aatttgcttg ccttttatgc tcggtacttt agctgtacgt gcaatattta ctggtgatcg
    15241 ttacatacta gaatattttt atgatgctaa tattttagcg gcgtatgtct tttttgcttc
    15301 gttagctgct gcaacaatga gttttatgga tgcagcggtt ttttcatttg attaccctga
    15361 gctggtgaga tcaataaata cacgagataa taagcataga gagcttataa aaaaactata
    15421 taaaaaagta gcatttttac tgattttgat taatctgagc gcatatgttt ttattgattt
    15481 gttgttaaga ttaattggaa aagacatttt taattcttat ctaaattact tttatttgtt
    15541 aatgttagtg caggttttat atgcttttag catgatccct cattatattt tatatgcctt
    15601 ggatgcagat aaacctatta ttggaactca aatatctagt ttggttatct ttcttttatt
    15661 ttgttttagt ctgattggat tattgcagga agattatggg atatttgttg cattattggc
    15721 ttcattctct ttcttgtttt tgtcgaaata tatctattct tggagattgt taaagagata
    15781 tgaacattct tattctagtt aatccagcga aaaattataa atattttttc tataatgttg
    15841 ctaaatcatt ggtagattta ggtcatagtg tatattatgc gtatgacact gaaaaaaata
    15901 aaattttatt tcctatccct gaaatagatg agtcatctaa gagctatttt tttgatgttt
    15961 tttttaaaat taatcaagaa gaaaatttgc agtctaatga tgaatttctt tttgattgta
    16021 cttgggggga atatttctat tcggattttg atcgattttt aactcatggt tataatttag
    16081 aaaaagatgc tgaagagtgg gtaaaaatcc gtaaaaagat ggatagtttt ttttataaaa
    16141 ttataacaga aaaaaatatt gatctcgtgt tgtatgaaaa tatttccaat agttttgagt
    16201 actcagcata tagagtggct caaacattag ggaaaaagta ttttggttta attgcatcac
    16261 gcatacctgg gcgctatgaa attcaaactt ctatcattga tgatttattg gtggatttag
    16321 aattggtgaa ggaaaagccg cttacagaag aagaaataaa ttggtatgaa gattataaat
    16381 ctaatattaa taaaattgaa cctgactata tgaaacaaaa tggtttagat aatgtttctt
    16441 tattgaataa ggtgagttct aatatttttt ataaaattat taggtctata aaagctgata
    16501 ttaaatatgg agcaaaatca gattatgcta gtgggcttct atttttgagg attttgtcgg
    16561 ctgttaaagt tgctgtaaat agacgattaa atcataaaaa aacaaaaaaa tactttctaa
    16621 aaatggatga ggttaatgag attaaacagc aacataagtt ctatgtttat cctatgcact
    16681 atcatcctga atcatcaacg tcggtattgg ctccacaata tacaaatgaa tatcacaata
    16741 tattaaatat ttctaataat ttgccatttg ggcaatattt gtatgtaaaa gatcatagaa
    16801 gtgcaatcgg cttaaactca gatgagtttt atagaaaaat ttcagcatta cctgcagtta
    16861 ggttaattcc cgcagagtat aatattaaag atttaataaa atactctgct ggcgtgataa
    16921 cggttaatag tactgctggt tatgaggctc ttattttggg taagccagta tatttgctgg
    16981 gtaatgtttt ttatcagaac ttttctaatg ttgtccgtct agaaaatttt aatagcctta
    17041 aatcttgttt agaaaagcct actgagttta ttgaaaatgc agcagatatt gttgcttaca
    17101 gacgggtaac ttatgaaggg attctgaact ttaatatgat tgaatatgat tctaataaag
    17161 ttttttttga caagcttgct atgaatatcc aggaaaatat gttgggtaaa acctaagtta
    17221 tatttatttt ctattcgcag tatattgaaa agaggttggt agtgatttta ttagcatatt
    17281 gtgtattgtg tataataacg attatattga ctttttttga tagccggcaa aagttaattt
    17341 atgttttttt gtggatatgt ctcataacct ggtctatagt atctcgaaat gctgtactac
    17401 agcaggatat gcttgtttac tctgaagcaa tgacatatga ctggagtttc tataaaactt
    17461 tttatacttt aagagagcct gtttattggc tctctagtaa gtatttgttt gaacttttac
    17521 atagtaatgt gcttgtcttt attattctgg atactatatt cctatcggct ttagtttttg
    17581 caggatataa gtataagatt aagccatatt ttattttact ttttatattg tttttcccta
    17641 atttaatggg gtttttaaat atttatcgtc aatttttagc tacgatagct ttgtttattt
    17701 gtttttttat gttgtaccat aatcttaatg gttctcggtt aatatacttg gtttcacttt
    17761 ttatacataa tgttagtatt gtttttttgc ccattctttt tattaaaaag accttctttc
    17821 aatttttatt tatagttttt tcttttattt ctattgcttt aatggttttg ttttcagggt
    17881 cgaaatctga agtggataca ggagaggttt ctccattttt atttcttgct gtgatttgta
    17941 taattgtaac tatctttttg tttttaaata agcttgtgtt gtatagaaaa aatattgatt
    18001 tatattatat taatttttac tgcgttcttg tttcagcttt ttcttcttta ttccttgcag
    18061 gtgcaccagc aaaaagaatc tgtatgatag cattatcatt tttgttatat tctatttatt
    18121 ggtttattga ggataatagg aagaatattc tattatttcg tattatattg gtggtttttt
    18181 ctttaattcc tacctttatt ttttcttctg cgtttttaat gcttttgaat aaaacaacgt
    18241 gatgtaggtg aaagtaatat ttttgagtaa gagattatcc aagtatataa attttctttt
    18301 taagaggtat tgatatgttc ttttcaattt tattatcctt atatcataag gaaaaaagtg
    18361 aatactttga tcaatgtttt gaaagtattt ggactcgaca aatactgaag cctacagaaa
    18421 ttgtattagt acttgatggc ccaataggta atgagttaac taattctgta caaaaatggc
    18481 aatcaaaaat tggtgatgcg ctaaaaatta ttgcactccc tcaaaatgtt ggactgggaa
    18541 aagcattaaa tgaaggttta aaacattgta cttatgaatg ggtctttcgt atggatacgg
    18601 atgacatctg taccgctgat cgttttgaaa agcaggctgc tttcatacaa cagcatccag
    18661 atgttgtatt gtttagtgga caagtgatgg agtttgatca ggacatttct gatgcaaatg
    18721 tcctgaaatc ggtgccagtg acacatgaag aaattaaaga atttgcacaa aagcgctgcc
    18781 catttaacca tatgactgtg gcttataaac gagatgtaat tttaggttta ggtggttacc
    18841 agcaccattt attcatggaa gactacaatt tgtggttacg ggtgattgga aataactaca
    18901 aagtagcaaa cttggctgat gttttgcttt acgctcgtgt tggtaatggc atgcactcac
    18961 gtcgtaaagg tttccaatat attaaaagtg aaaaacagtt actagattta aaaaaacaac
    19021 taaagttaca aaatcctcta tatgctaaca tgctgtttct ggtacggtct gcgtttagac
    19081 tgttaccagc aaatttattg ggtaaaattt ataatacctt tcttcgtaaa gatattaaaa
    19141 aatgagtgaa tgaaaatatg aagcgtttag tagacatagt catttcttta atagctttaa
    19201 ctgttctgtc gccaatattt ctgatagttg cttataaagt ccgtaaaaat ttaggttcac
    19261 caatattctt ttaccaagaa agacctggta aagacggaaa attatttaaa atgattaagt
    19321 tccgttcaat gaaagatgct tttgatgctc aaggaaatcc attgccagac gaagctcgta
    19381 ttactccgtt tggacaaaaa ctgcgttcaa ctagtctaga tgaaatgcca cagctcatta
    19441 acgtactaaa aggtgacatg agtgtggtag ggccgcgtcc aatgctaaaa gattttgttg
    19501 ctttatattc accagaacaa gcgcgtcgtt tagaagtacg ccctggaatg acgggtttag
    19561 ctcaagtaag cgggcgtaat gaacttgatt atgaagaacg atttaagtgt gatgtatggt
    19621 atgtagataa tcacaacgtt tgggttgatt tcaaaatcat gtttaaaaca gtcaaagtga
    19681 tgttaaaacg tgaaggaatt aatgctccag ggcatgttgg gccatcttta tttaaaggta
    19741 atgataccca agaaaatatt gattcttctg ttaagtaaat tttatatctt gaaatctttc
    19801 ttatgattaa aaaagcagtt ttaccagtag ctggtttagg tacacgtttt ctaccggcaa
    19861 gtaagtctat tccaaaggaa atggtaacgg tcgttgatcg tcctgcaatt gaatatgtag
    19921 tacgcgaggc ggtagaggct ggaattgaac aaattatttt agttactcat tcatcgaaag
    19981 catcaattga aaattatttt gatcgtaact ttgagttgga aaccactcta gaacaaaaga
    20041 aaaaattcga tttacttgca gagattactc aaattgtgcc tgagcatgtg agtgtagtaa
    20101 gtgtaagaca acctcagcct ttaggcttag ggcatgctgt gttatgtgca aagagtgttg
    20161 tcggtcaaga tgatttcgct gtgctattac cagatgtatt ggtgaaagat agctctggac
    20221 aaaatgatct atcccgtatg atttctcgct ataactcaag ccaagctgct caaatcatgg
    20281 ttgaagcagt gccagaccat ttagtagatc aatatgggat tgtggatgta aaacatagcc
    20341 caaatgaagg tgaaagcatt gctatgcagg gtattgttga aaagcctgca gtaggctctg
    20401 caccatcaaa cttatcagtg gttggccgct atgtgttacc tgccaagatt atgcaattac
    20461 ttgagaacac gccgaaaggt gcgggtaatg aaattcagtt aactgatgca attgcaatgc
    20521 ttcaagacac agatactgtt gaagcttatc gtatgcaagg tcaaacgttt gattgtggta
    20581 gtaagattgg gtatttaaaa gctgtactac actatggaat tgaacaccct aagttaggaa
    20641 atgattttaa acagttaatt caggaactta aattataaaa ttttgtagct ctgcttaact
    20701 atttgtaaaa acgaatgaat atatgaacag agcaatatat tctcttcctg gaaagggaag
    20761 agaattttat agaatattaa aatcaggtgt acaatgaaaa tcgcggtatt tggaaccacc
    20821 ttacatgctg gtgtaatggc agcattatta gctgaatatg gcaatcagat ctattggtgt
    20881 acaagtgtca cctgtgaaga aaacatttct atactttctt atcaagatca agaagttaat
    20941 cattatttaa ataaacagag aaaagcaggt tttttaaaag aaagtccttt ttctgaaatt
    21001 cctttagata ttgaagttta tttattttgt tttagcccaa cacaaatcga gcttgcttta
    21061 aaaacagttg aaaagttgag tgagcgcccg atagttcatc cacgtttaat gatcaatggc
    21121 tctacttttg gtctacatgg tacgaatcaa ttaaaacaac atttgccaaa agatgagtgg
    21181 gtttattttc ctgatgtgat tcaagaagga aatgcgatta atagcgtgct gaacgtaaaa
    21241 catgtaattg ttggtgttga atcgagttat gctcaagaca ctatgcaaga gctgttacgt
    21301 ccttttttcc gttttagcta tcaatattta tttatgccaa ttttagatgc tgaatttaca
    21361 aagctcagca tttcgggaat gttggcaacc cgtattagct acatgaatga tttggcgatg
    21421 gtggccgaaa aactcggtat tgatattgct aatgtaaaac atggtattgc tgcagataca
    21481 cgtattggtg cagcctattt gtcggcaggt gttggatttg gtggtgaaaa cttttcacat
    21541 gatattttaa cgctttcgag tactgtatct ggaacagggg ctaaaagtcg gttgctagag
    21601 caagtgtggg cgattaatga gcaacaaaaa gaaattttat tccgtaaatt atggaattat
    21661 tatcactgtg atttgagcgg taaaactgtt gcgatctggg gggcttcatt taaggaaaac
    21721 acctctagca ctcataactc acctattcat attttgttag ctgcattatg ggcacaaggg
    21781 gtaaaagtac gtttacatga cccacaagcc ttagatgaga tcgcaacaac ttatggagac
    21841 cgtgaagatc tggttttatg tgctgaccaa tatgaagctg cacagggagc tcatgcttta
    21901 tgcttagtga cagcatggaa acaatattgg agccctgatt ttaaacagtt acaacaagta
    21961 atgcagcatc ctcttatttt ggatgggcgt aatatttacg atccggcata tgtgaaagca
    22021 aaaggtttcg cttatgaagg agtaggtcga ttatgagtaa atctatcgag aagtttccta
    22081 aagagttagt ctcgcctata gcacagcttc attcattagt tgagaagaat tcaaaattac
    22141 atatcaaaga attatttgca gccgagcaag accgctttca aaactattcg gtaaagttcg
    22201 atcaattggt ttttgattat agtaaacacc gtataactaa aagtgtttta gaacaattgt
    22261 ttgctttagc aaagacgaaa caattaactc actggattga gcggttattt tcccaggaca
    22321 aagtcaattg tactgagcag cgtgcagcta tgcactgggc cttacgttta ccatcggaat
    22381 attctaaatt tcctgaactc acaaaacagg ttcatactca attacagcgt atgtatgttt
    22441 tggttgaaaa aatccatgct gggcaatacc gcggtgctac gggtgaagtg attcaggatg
    22501 tcgttaatat tggtgtaggt ggttccgatt tagggcctca aatggtgacc catgcactat
    22561 gcgattttaa agtaaaaact gccaaaccac ttaatgtaca ctttgtttcg actatggatg
    22621 gtagccagtt atcagaccta ctccatcaac tgcgtccgga aacaacttta tttattattt
    22681 cttcaaagtc atttggtacc attgatacct tatcaaatgc acagacagtt cgtcagtggc
    22741 ttgaaaaagc tttaggaaaa catgaccgcg ttgtaaaaag tcacttcatt ggtgtatcta
    22801 caaaagctga aaaaatgact gagtggggga ttgctcctga aaatcagttg ttgctttggg
    22861 actgggtagg tggacgttat tctctttggt cttgtattgg tttccctata gccctaacga
    22921 ttggtataga tggctttcaa cagcttttgg ctggcgcaca tgctgttgat gaacactttc
    22981 aaaatacaaa ctttgagcaa aatataccgg ttctcatggc attactcggt atctggaata
    23041 ataatttttt aaatattcaa acccatgcgg tattacctta tgacggaaga ttaaagtatt
    23101 ttgctgccta tttgcagcag cttgaaatgg agtctaatgg taagtcggta caacgtgatg
    23161 gccaaaaagt tgaattagat acttgtccga ttgtatgggg tgaggttggt ccaaatgccc
    23221 aacatgcatt ttatcagcta cttcatcaag gaacacaggc agtaagctgt gatttcattg
    23281 caccgatcca acgttataat gcagatcact ttacgtatgt ggagaatgct gaggcattga
    23341 ttgaacaaca tcacctcgca ttatcaaatt gtttggcgca atcacgttta ttggcttttg
    23401 gtaatgaagc tttggattca gctgaactaa agaatttacc aatttataaa caatatgaag
    23461 gtaatcagcc gagttcgaca ttacttttaa aagaactaaa tccatatagt ttagggatgt
    23521 taattgcttt atatgaacat aaggtatttg ttcagtcggt aatttggaat attaatccgt
    23581 ttgatcaatg gggtgttgaa aaaggtaagc agattgctga tcagttactt ccaattttaa
    23641 atggtgctca aaatgatctt tcaacacttg atgcttcaac acgtggtttg attaaaattt
    23701 tattaggaaa agtcgatggc taaaatttta gttacaggtg gtgcaggtta tattggttca
    23761 cacacttgtg tagagctttt agaagcaggc catgaagtta ttgtatttga taacctttca
    23821 aatagctcaa aagaatcttt aaatagagtt caagagatca cacaaaaaag tttaactttt
    23881 gtggagggcg atattcggaa ttctggtgag cttgaccaag tgtttcaaga gcacgcaatt
    23941 gatgcggtta ttcattttgc aggtttaaaa gcagtaggtg aaagccagga aaaaccgctt
    24001 atttattttg ataataatat tgcgggcagt attcaactgg ttaaatcgat ggaaaaggca
    24061 ggtgtctata cacttgtatt tagctcttct gcgacagtat atgatgaagc aaatacctct
    24121 cctttaaatg aagaaatgcc aacaggtatg ccaagtaata actatggata tacaaaacta
    24181 attgttgagc aattattaca aaaactttca gtagctgact ctaaatggtc tattgcctta
    24241 ctacgttatt ttaacccagt aggtgcacat aagagtgggc gtattggtga agacccgcaa
    24301 ggtattccaa ataatttaat gccttatgtg actcaagttg ctgtgggccg ccgtgagaaa
    24361 ctatctattt atggtaatga ttacgataca atagatggta caggtgtgcg agattatatc
    24421 catgttgttg acttggcgaa tgcacattta tgcgctttaa ataaccgctt acaggcgcaa
    24481 ggttgccgtg catggaatat tggtacaggt aatggttcat ctgttttaca agtcaaaaat
    24541 acctttgaac aagtgaatgg tgtacctgtt gcttttgagt tcgctccacg tagagcaggg
    24601 gatgttgcga cttcttttgc ggacaatgct cgcgcagttg ctgagttggg ttggaaacct
    24661 caatatggct tagaagatat gcttaaggat agctggaatt ggcaaaagca gaatcctaat
    24721 ggctacaatt aaattcggat aaaaaaggag cgatttgctc cttttttatt tttaattagt
    24781 tctgaattaa tccagtcaat tcatctacat aatgttgcat tggctgagct tgacggtctg
    24841 cacggctttc aatgttgagg cgtaataacg gttcagtatt tgaagcacgg acgttaaagc
    24901 gccatgcgcc aaagtcgagg cttacaccat cggtacggtc aatttgtgga ttttgatcgg
    24961 catagaagtc gaaaatcttt tgaatcgtag tttgcgtatc gactacttta aagttgattt
    25021 caccactaca agggaacttg gcaatcatat tttcaacgag tgttgagaga gattgtcctg
    25081 tttcagagag tagagcaatg gtgagtaacc agggaatcat accactgtca cagtaagcaa
    25141 aatcacggaa atagtggtga gcactcattt caccgccgta tacggcattg tgttcacgca
    25201 taacatcttt aataaatgca tgccccgatt ttgactgtac agcaacacct ttatattcgt
    25261 tgacgatatc aaatgtgttc cacactaaac gtgggtcatg cacaattttt tcgcctgact
    25321 gtttgattaa gaaagcttga gccaataggc cgacaatata gtagccctca atgaattgtc
    25381 ctttttcatc gaacaagaaa cagcggtcaa agtcgccgtc ccatgcaata cccatatctg
    25441 ctttatgctc aagaacagca tttcgggtac tgtcacggtt ttcaattaaa attgggttag
    25501 ggatgccatt tgggaaagta ccatctgctt catgatgaat tttaataaat tcaaccggta
    25561 cattaagcgc tttaaatttt tcttcaatgg catcaatcac atgaccagct gcaccattac
    25621 ccgcatttac cactaacttt aatggacgga tttttgcagg ttcaatataa gtcagtagat
    25681 ggtcaacgaa ctcaggcaaa atattatagc tttgagttgt acctttttgg ctaacttctt
    25741 caaagttatt ggtctctgct aaagcctgaa tttcttttaa accagtatcg gcactaattg
    25801 gacgagcatt ttctcgaacc aatttcatac cgttatagtc cattgggtta tgactcgcag
    25861 ttacttctat accaccttgt acgtctaaat ggaaagcggc aaagtacact tcttcagtgc
    25921 ccgtcatgcc taaatcaagc acattcacac ccgcatcatt taaaccgcgg atggtcgctt
    25981 gttttaaagc ctcactgctt agacgaatat cacaacctac aaccacagtc tttggtttat
    26041 agatttgtcc gtaagcgcgg ccaattttat aggcgatttc ttcattcaat tcggtgccga
    26101 gtttgcctcg gatatcataa gctttaaaac acgttaaagt agtcattatt caattcaata
    26161 catgtggttt gagttgtgtg cacattatac atagatcatc aaattggtac gtttatagtt
    26221 tttatattca aattttgcac ttcatttctg taggtcatat ttaagtttat aaggaagctt
    26281 ttttacgact ttagtcgaat aaataaataa attagaaata gcttgatttt tcttagttat
    26341 attggtcata ccaattatgg taattattta atcattgatc tttccaataa ctgtgtttat
    26401 gatgcgcatt gtggtttaag gaaaaacatt tgcacttaaa ttttaattgg tcataccaat
    26461 ttgtgttaaa tgttgaaatt ttaaggtaca aaaattcgcc ccggcatttc aaggagatga
    26521 caatgctcaa tatgtggcaa caactttatg accctttaaa taatatttgg ctgtctagtg
    26581 cggttgcatt aatcccgatt attttcttct ttttggcctt ggctgttttt cgtttaaaag
    26641 gcagtatcgc gggtacgggc acagttatta ttgcattact gattgcgcta tttttctatc
    26701 aaatgcctgg tcaaatggcc tttgcgtcaa tcatttacgg tttcttctac ggtctatggc
    26761 caatttcatg gatcattatc ggggcagttt ttctatacaa gatttcggta aaaacaggcc
    26821 agtttgaggt tattcgctca agcattctat ctattaccga agaccaacgt ctgcaaatgt
    26881 tacttgttgg ttttgcattt ggtacttttc ttgaaggggc tgcgggtttt ggtgctcctg
    26941 tcgcaattac cgctgcacta cttgtcggtt tagggtttaa gccactttat gctgctggtt
    27001 tatgtttgat cgtaaataca gcgccagtgg catttggtgc gatgggtatt ccaattattg
    27061 tggcggggca ggtttccggt gtagacacta tggaaattag ccagatggtg ggtcgtcagt
    27121 tgccattttt aaccattatt gtgctgttct ggattatggc gattatggat ggctggcgtg
    27181 gtgttaagga aacttggcct gcggtattgg tcggtggtgg tgcttttgcg attgctcagt
    27241 atctcacctc taactttatt ggccctgagt taccagacat taccgcagca attgcttcat
    27301 tggtcagcct gacgttgtta ttccgtgttt ggaaaccaaa acatattttc cgttttgaac
    27361 ctgaagcggg tcagactttg actcagcaac ctacaacagt tcaacgttat agcattggca
    27421 aaattgcaaa ggcatggtct ccatttgcta ttttaacggt aatggtcacg atttggagcg
    27481 ttaagccatt taaagcatta tttgcaaaag atggtgctct tgaacactgg atttttaaac
    27541 ttgaagtgcc gtatttacac aaattggtcg agaaaatgcc accgattgtg tccgagatga
    27601 aaccatacga agcgatttat aagtttgact ggttctctgc aacaggtact gcaattttta
    27661 ttgctgcgat catcacagtt attttcttaa aaatgaaagc aagtgaggca gtaacaacct
    27721 tcggtgaaac tctcaatgag ttaaaaacac cgatttactc gattggtatg gtgttggcat
    27781 ttgcttttat tgcgaactat tcaggtttat ctgcaacttt ggctttggct ctatcgcata
    27841 cggggcatgc gtttactttc ttctcgccat ttttgggttg gcttggtgtg ttccttactg
    27901 gttcagacac ttcttcaaat gctttgttct cggcattaca ggcaaccacc gctcagcaaa
    27961 ttggtattcc ggaagtgtta ttggtcgctg cgaataccag tggtggtgtg acaggtaaaa
    28021 tgatttcgcc acaatcgatt gcgattgctt gtgccgcagt aggcttagtt ggaaaagagt
    28081 ctgacttgtt ccgtttcacg gtaaaacata gcatcatatt cactgtcttt gttggcatca
    28141 ttatcacggt tcaggcttat ctggttccgt ggatgattcc ataactccag tgaaggaaac
    28201 gcgatgagaa tctccgatca agtggtcatg aaattgcagg cattaattga agagcgtcac
    28261 atgaaaaaag gtgaccgctt gcctgccgag cgccagcttg caactagctt aggagtttct
    28321 cgtccatcct tacgtgaagc aattcaacag ctcaatagtc aaggtgtact gattagtcgc
    28381 cgtggtgatg gaacttatat tcagcaatta cctgaacaat ggccacagca actgattgtg
    28441 aatccaatca gtaacctgat tgaagaagat ccgttatacc gttttgatgt gcaagaggcg
    28501 cgtttggtgc tcgaaggggg aactgcatgg tatgccgcgt tacgttcgac cccagaagat
    28561 cgcgccaaaa ttcatcatta ttttaatgaa attagtcgcc atcaaaatgc gggtgactca
    28621 gcacaggctg cggtcgcgga tgctgaattc cacttagcga ttgctgaagc atctcacaat
    28681 gtggtgctga ttcaaatgat gcgaagtcta tttgatttgc tgcaatacaa cgtcttgtta
    28741 gggcgtaaaa aagtttataa cgaccccgta aatggtgact tgctgagcga gcagcatttt
    28801 caggtgatgg atgctattga tcgtaaagat cccgaggccg cacgccaagc tgtctgcggt
    28861 catattgaat ttgtgattaa tcatgtgcgt tctctggatg aagacgaagc tcgccagaaa
    28921 cgtgcaaacc gtttaaatag agttgattca aaatgattat ttcttctggc aatgattatc
    28981 gtgctgcggc acaacgtcgc ttacccccat ttttatttca ctatattgat ggtggagcgt
    29041 atgcggaata taccttaaag cgtaacgtac aagatttgtc agaaattgca ttgcgtcagc
    29101 gtgtgctgaa tgacatgtcc gcgttgagtt tagagacaaa actgtttaat gaaacgctgt
    29161 cgatgccagt tgccttggct cctgtgggtt taacaggtat gtatgcacgc cgtggtgaag
    29221 tacaagccgc aatggcagcc gataaaaaag gtattccatt tacgctttca acggtttcag
    29281 tttgtccgat tgaggaagtt gcacctgcaa ttaatcgccc gatgtggttt cagctttatg
    29341 tgttacgtga ccgtggtttt atgcgtaatg ctttggaacg tgcaaaagca gcaggttgtt
    29401 caacactggt atttaccgta gatatgcctg taccaggtgc acgttatcgt gatgctcatt
    29461 cgggtatgag tgggccaaat gctgcgatgc gtcgttatat gcagtcagtg tttcatccgc
    29521 actggtcatg gaacgttggc ttaatgggac gtccgcatga cctcgggaat atctctaaat
    29581 atttaggtaa accgactggg cttgaagact atattggctg gttaggctcg aactttgacc
    29641 catccatttc atggaaagac cttgagtgga tacgtgaatt ttgggatggc ccaatggtga
    29701 ttaaaggtat tttagatcct gaagatgcca aagatgctgt gcgttttggt gctgacggga
    29761 ttgtggtatc aaatcatggc ggtcgtcagt tagatggtgt gatgtcatct gctcgtgcat
    29821 tacctgcaat tgccgacgca gttaaaggtg acttagcaat tttggctgac tcgggcattc
    29881 gtaatggttt agatgtagtg cgtatgttgg cgctcggtgc cgatacggtt ttacttggcc
    29941 gtgcgtttgt ttatgccttg gcagcagcag gtggacaagg tgtgtcgaac ttacttgatt
    30001 taattgataa agaaatgcgt gttgcgatga ccttaacggg tgctaagtcg atttcggata
    30061 ttaatgcgga ttgtttagta caggcgatta aacaaggact ttaa
//
