LOCUS       KC526896               31233 bp    DNA     linear   BCT 17-JUL-2019
DEFINITION  Acinetobacter baumannii strain LUH5535 KL35 capsule biosynthesis
            gene cluster, complete sequence.
ACCESSION   KC526896
VERSION     KC526896.2
KEYWORDS    .
SOURCE      Acinetobacter baumannii
  ORGANISM  Acinetobacter baumannii
            Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
            Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
            complex.
REFERENCE   1  (bases 1 to 31233)
  AUTHORS   Hu,D., Liu,B., Dijkshoorn,L., Wang,L. and Reeves,P.R.
  TITLE     Diversity in the major polysaccharide antigen of Acinetobacter
            baumannii assessed by DNA sequencing, and development of a
            molecular serotyping scheme
  JOURNAL   PLoS ONE 8 (7), E70329 (2013)
   PUBMED   23922982
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31233)
  AUTHORS   Shashkov,A.S., Liu,B., Kenyon,J.J., Popova,A.V., Shneider,M.M.,
            Senchenkova,S.N., Arbatsky,N.P., Miroshnikov,K.A., Wang,L. and
            Knirel,Y.A.
  TITLE     Structures of the K35 and K15 capsular polysaccharides of
            Acinetobacter baumannii LUH5535 and LUH5554 containing amino and
            diamino uronic acids
  JOURNAL   Carbohydr. Res. 448, 28-34 (2017)
   PUBMED   28578199
REFERENCE   3  (bases 1 to 31233)
  AUTHORS   Reeves,P.R., Hu,D., Liu,B., Zhang,Z. and Wang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JAN-2013) TEDA School of Biological Sciences and
            Biotechnology, Nankai University, 23 Hongda Street, TEDA, Tianjin
            300457, P.R. China
COMMENT     On Jul 17, 2019 this sequence version replaced KC526896.1.
            
            ##Assembly-Data-START##
            Assembly Method       :: velvet v. 2.0
            Sequencing Technology :: Illumina; Sanger dideoxy sequencing
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..31233
                     /organism="Acinetobacter baumannii"
                     /mol_type="genomic DNA"
                     /strain="LUH5535"
                     /serotype="O6"
                     /db_xref="taxon:470"
                     /note="serogroup: PSgc6"
     gene            1..1542
                     /gene="mviN"
     CDS             1..1542
                     /gene="mviN"
                     /note="integral membrane protein MviN"
                     /codon_start=1
                     /transl_table=11
                     /product="MviN"
                     /protein_id="AHB32278.1"
                     /translation="MALWRSTFIVSAMTMLSRVLGLVRDVVLLNVFGAGKDFDTFVVA
                     FRIPNFFRRLFAEGAFSQAFIPVLTEYKTGRAHAEVQILISRVFGCLLTVMTLLTFVA
                     MVLAPAIIYMYAPGFHNDPEKFDLAVSMFRLTIPYLMFMSLTAFASSILNSYGSFASP
                     AFSPVLLNVAMIAGAWWLTPYMAEPIKALGWSVVAAGILQLAIQIPELWRKNLLIPPK
                     VDFKHEGVERILKLMLPALFGVSVTQINLLLNTIWASFMQDGSVSWLYSAERMTELPL
                     GLIGVAIGTVILPSLSARHAEQDQAKFRSMIDWAAKVIVLVGLPASIALFMLSTPIIQ
                     ALFQRGEFDLRDTQMTALALQCMSAGVISFMLIKVFAPGFYAQQDTKTPVRVGLMSVA
                     ANAILNVVFIGFFKLINWHAEHMALALASSGSALVNAGLLYFYLHKRNIFRFGAHWKK
                     LALQYGLANLAMIAALWFGLNWYNGELSQWLRVAEVVGLCVVGVIAYAIGLFASGFRP
                     RHLKA"
     gene            1676..2683
                     /gene="orf46"
     CDS             1676..2683
                     /gene="orf46"
                     /codon_start=1
                     /transl_table=11
                     /product="Orf46"
                     /protein_id="AHB32277.1"
                     /translation="MNLAPYTSFPCLIIISSIAFANSNLFQDNMDITDLVNNKIKENS
                     LIKIPAGNFKINAEKSIILKNNVTIEMSPKTVLNVIPNEANSYQVFKIHNVNNVRISG
                     GTIIGDKYTHRGTKGEWGTGIEIKDSQNIYLSNIIIKKMWGDAIYIGNNGKNSNSNLN
                     LINLKLDDNRRQGISIVSVNGLFANNIIISNTRGKSPMSGIDIEPNNNRNILKNIKFS
                     QISTVNNAGDGFQISLKKYNNSMQGVSISLSEYNDYGSRSGIRIQGLKTPVIGEININ
                     KVNLKNNKISNYCFKDWENNKVKIKITNLLHDKEYIKNQDKWCSPYTNNDFLKVVKRD
                     N"
     gene            complement(2719..3408)
                     /gene="fklB"
     CDS             complement(2719..3408)
                     /gene="fklB"
                     /note="FKBP-type 22KD peptidyl-prolyl cis-trans isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="FklB"
                     /protein_id="AHB32276.2"
                     /translation="MKKISLVIAASTMSLSVFAAAPITNKSPAKDQFSYSYGYLMGRN
                     NTDALTDLNLDIFYQGLQEGAQNKTARLTDEEMAKAINDYKKTLEAKQLVEFQKQGQQ
                     NAQAGAAFLAENAKKSGVITTKSGLQYQVLKEGTGKIPKATSRVKVNYEGRLLDGTVF
                     DSSIARNHPVDFQLNQVITGWTEGLQTMKEGGKTRFFIPANLAYGEVGAGDAIGPNST
                     LIFDIELIKIL"
     gene            complement(3459..4181)
                     /gene="fkpA"
     CDS             complement(3459..4181)
                     /gene="fkpA"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="FkpA"
                     /protein_id="AHB32275.1"
                     /translation="MSKALPIAVAVVLGGAALVPVYYATQHPTTEVGRKADKNASPIQ
                     KISYVLGYEVAQQTPPQLDTKAFVQGIHDARNKQPSAYTQEDLKAAVAAYEKELQQKM
                     QHQDKPEQSGTATDSADAQFLAENKTKAGVKTTASGLQYIITKEGTGKQPTAQSIVKV
                     HYEGRLINGQVFDSSYKRGQPVEFPLNQVIPGWTEGLQLMKEGGKATFFIPSNLAYGP
                     QELPGIPANSTLIFDVELISVK"
     gene            complement(4373..6556)
                     /gene="wzc"
     CDS             complement(4373..6556)
                     /gene="wzc"
                     /note="protein tyrosine kinase; involved in capsule
                     export"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzc"
                     /protein_id="AHB32274.1"
                     /translation="MNQNTNIEDTIDLKELFFSLIAQWKLIALCVILSLVCALIYLRV
                     TPNTYSVDALVQVEDSKGASAALLGDLSNMIEQKSPAQAEIEILKSRLVLGSVIKELH
                     LNIQVSSTENTFSHRLLSDTDYKTEYSKKSVIFKDGLKSFEIRTLEVPAYYLDKTLHL
                     NFDKQSVRLTDPATEQTLLTIPLNQLNQVTGPYGTWKVGIFTKDQFNTTYNIKNLSVP
                     AAVNAISSKYSVAERGKLTGVLGLNYQGQDKEHITKVLNAILATYSAQNIERRSAESA
                     QTLKFLDEQLPDLKKQLDDAERQFNKFRQQYNTVDVTKESELYLTQSITLETKKAELE
                     QKQAEMAAKYTAEHPAMREINGQLSAINKQIGELNSTLKQLPDVQRQYLQLYREVEVK
                     TQLYTALLNSYQQLRIAKAGEIGNVRIVDTAVEPIEPIKPKKLQILILSIFLGGFIGT
                     LIALLRNMLRTGIKDSGQIENELDLPVYATVPRSPIQESRIKILKKKKSIPILAIKNS
                     DDIAIESLRSIRTAIHFALANAKNNIIMIAGPSPEVGKSFISTNLATIFAQGDKRVLL
                     IDADMRRGYIHKYFDVEVKPGLSEFLSGQADLQKVLHKTQVDNLDVITRGKSPTNPSE
                     ILSSNQFKELLEQLQSQYDHIIIDTPPVLAVTDGIIISQYTGVNLIVARYAKSQMKEL
                     ELTVNRFEQAGVKVNGFILNDIQRASAGYGYGYNYAYAYKAQKED"
     misc_feature    4373..27270
                     /note="KL35 capsule biosynthesis gene cluster"
     gene            complement(6575..7003)
                     /gene="wzb"
     CDS             complement(6575..7003)
                     /gene="wzb"
                     /note="low molecular weight protein tyrosine phosphatase;
                     involved in capsule export"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzb"
                     /protein_id="AHB32273.1"
                     /translation="MEIKNILVVCIGNICRSPMAEYFLKQQYPQLNIESAGISGLIGH
                     QADEKAQLCMQRLGIDMKPHIARKLSAEHIKKADLVLVMSHNQQKHIEQNWPFAKGKT
                     YRLGHWQNRNVPDPYQHDQAFFDETCQLIQQCIADWKPYI"
     gene            complement(7008..8114)
                     /gene="wza"
     CDS             complement(7008..8114)
                     /gene="wza"
                     /note="outer membrane protein; involved in capsule export"
                     /codon_start=1
                     /transl_table=11
                     /product="Wza"
                     /protein_id="AHB32272.1"
                     /translation="MLVKYCQFFSVLALSLSAASCAVTSGLQTYDVPSEGVYRTELGT
                     TVNVVKISQESLPAIQPAQVDYQRDYATLFKNQQPIYRLSSGDVLSIQLWAYPEITPP
                     VNNVNNEQSVQANGYPIDQSGYIQFPLVGRYKAAGKTLTQVNRELRSQLARFLKNPDV
                     IVRVLSYEGQRFSVQGSVTKGGQFYLSDQPVSIYTALGLAGGVSDKGDNTYIQLIRNG
                     RTYNLNTIDLEKAGYSLHKLLVQPNDTIYVSTRENQKIYVMGESGKNQALPMRDQGMT
                     LTDALGESLGINPLSASASRIYVVRTNQNDHTTAIYHLNLMSLGDFGLANQFKLRSND
                     VVYVDATGLTRWQRVVNQVIPFSNALYNIDRLGQ"
     gene            8486..9760
                     /gene="gna"
     CDS             8486..9760
                     /gene="gna"
                     /note="UDP-N-acetyl-galactosamine dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gna"
                     /protein_id="AHB32271.1"
                     /translation="MQLADLRIAIIGLGYVGLPLAVEFGKKVPVVGFDIYQKRVDELK
                     NGQDHTLEVSPEELKQATQLSYTANLEELKDCNFFIVTVPTPIDDYKQPDLTPLVKAS
                     TSIGKVLKKGDIVVYESTVYPGATEETCIPVLEQVSGLKFNQDFFAGYSPERINPGDK
                     LHRVTNILKITSGSTAEVAEFVDQVYNLVIEAGTHKAPSIKVAEAAKVIENTQRDVNI
                     ALINELAVIFNKMGIDTEAVLEAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQAIG
                     YHPEIILAGRRLNDNMGAYVVTQLVKGMIKKKIQVEGAKVLILGLSFKENCPDIRNTK
                     IIDIVAELKEYETQVDVYDPWVDRAEAEHEYGITPVQSVEKNTYDAVILAVAHEQFKE
                     MGAAAIRALGKNNHVLYDLKYVLSQAESDIRL"
     gene            9779..10804
                     /gene="gne2"
     CDS             9779..10804
                     /gene="gne2"
                     /note="UDP-N-acetyl-D-glucosamine-4-epimerase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gne2"
                     /protein_id="AHB32270.1"
                     /translation="MSQYQTVCEQLKHQPKTWLITGVAGFIGSNLLETLLKLDQKIVG
                     LDNFATGHQHNLDEVQGLVTPEQWARFTFIQGDIRNLEDCQKACANVDYVLHQAALGS
                     VPRSIADPITTNAANITGFLNMLVAARDAQVKSFTYAASSSTYGDHPALPKVEENIGN
                     PLSPYAVTKYVNELYADVFTRTYDFKCIGLRYFNVFGKRQDPNGAYAAVIPKWTAAMI
                     QGDDVFINGDGETSRDFCFIENTVQANILAATTENEEAKNQVYNVAVGDRTTLNDLFN
                     AIKNALKENQIMYVKDPIYRDFRKGDVRHSQASVEKIQNLLGYKAQYVISEGVDLAMK
                     WYVKNIS"
     gene            10801..11979
                     /gene="wzx"
     CDS             10801..11979
                     /gene="wzx"
                     /note="oligosaccharide-unit translocase"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AHB32269.1"
                     /translation="MNPRLLISKYKSIGVITSSLLVGAIITFIALPILTRLYSVKDFG
                     QYGVALAIVSVMSTIANLRLDQAILIAQAEEKKSLIFESILLAILFCIISSGVMVFIF
                     NPLMIFAINFGVLANIFIQCIYNYNFSIENEYFCACLNILRSLVVVIIQISFPFFYNA
                     NLLASYLISSLFIILLSLSYIFKYKIYRVGFSSFKGYKDFIFSNTPHALLNSFSHNLP
                     YYVVSHFLSYQVAGFYSIVERTLRLPINLMSQTIRQFFIRKFNTKGDYREALKSSLFL
                     SLVSLPFFLIFFALPESLYSWIFGSEWNGISTYFKILTLGYWAVFCNPPISGFLIAKR
                     RSDILLKLQIVELIIKALFFTLIYSLLDDKNSMLYAIPLSLIFYNFSIYFAVGKMKKC
                     "
     gene            11973..12572
                     /gene="atr16"
     CDS             11973..12572
                     /gene="atr16"
                     /note="acetyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="Atr16"
                     /protein_id="AHB32268.2"
                     /translation="MLILKFMKLFSIFFTSFRTLFYSSIFRTKIKKIGVNVTFDINGK
                     IDLGKNLVIESGATIIVEKGAKLQIGDNTFIGENTYIKCYGGSIQIGNNVSINSKCFL
                     NGAGGLLIGNNTRIGTQSIMISSNHIFERSDVLIKDQGTSREGITIGQDVWFGARVTV
                     LDGTFIVDRVVVGACSLINKSILENGVFVGIPARKVKEI"
     gene            12581..13666
                     /gene="wzy"
     CDS             12581..13666
                     /gene="wzy"
                     /note="oligosaccharide-unit polymerase"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AHB32267.1"
                     /translation="MNSMMINKRLIIYCIIFIFLCLFSIFRFEDGKVGDFLVTNYDEL
                     RYLLATDNIIQDTKVYGIIYTLENFYNYTQSVHFLHYFVLSFFRYFFNDSMVVWSLYQ
                     LSIYTLGCYFFGKFIRLEYDFISTNEEFLATVLMLLYPVFYFLTFSLMRDIAIFSLLS
                     ICLYFYKSNNYKLLILFIFVISLYRLNMMLCILVYILIDQFRDRSILSILKYLILSAL
                     ILFVVDKVSINFLSRHLSRIYEFNFLGLINEVLVFLLSPLPFSVDQSLPQYLRFWFMI
                     SFWLCVFLIFIYIIFIIKKKNIQLVLGAPIIGMSLFYIATYSIEAGIGFRQSSILLPF
                     IYIPIFLYFIKQFIPVKSYVNFKGTNE"
     gene            13663..14211
                     /gene="atr17"
     CDS             13663..14211
                     /gene="atr17"
                     /note="acetyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="Atr17"
                     /protein_id="AHB32266.1"
                     /translation="MNKLIRIFNYLYDIYFFIKKGSIKYARRKGVTIGNDCRIYIKEW
                     GSEPFLITIGDRVTITSGVRLVTHDGSTWLVRDENNSRYQKYAPITIGSNVFIGLNTI
                     VMPGVTIGDNVVVGAGSVVTKDIPPNSIAVGNPARVISTYDKFHQKIESSCVNNREIQ
                     HIVDYKERVYKAIEIGKSRDGK"
     gene            14201..15292
                     /gene="gtr71"
     CDS             14201..15292
                     /gene="gtr71"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AHB32265.2"
                     /translation="MVNNHLFVFPTAILGGAERVMFNIIYHLLLQQQNVTVVIMSRGK
                     QNGWERLQSFPNLDLIIYDYASEKKAILPLILGLIQLSMKCKFNLLFSSHTHINGLLS
                     FLKKIGFFRGSILVSRESTFIFDRFFGIKRFIFKFIYRFFYGQQNLIICQTQKMKNSL
                     ESALGYIPGKEMVVIPNPVNIDYIKSSISTVEKDNIIVGCGRFIPLKKFDFLLQAFEQ
                     LDSKYAHYKLVLIGEGPEAEKLEKMAKDLGVAEKVIFTGKINNPIQWFANARVGVISS
                     EIEGFPNVLIEMMASGIDYAISTPCTDGVYELPNIIVTADCSIGEIKKALERALEHQL
                     SYSEEYKEYIKKERSVASFWDRVLELTKS"
     gene            15289..16434
                     /gene="gtr40"
     CDS             15289..16434
                     /gene="gtr40"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AHB32264.2"
                     /translation="MKFLLIASYLPSVLNFRGKLLQAIQSQGFEIHIIAPDLRLFKTE
                     QQELEALGYHIHEIPMQRTGTNPISDLKTLWATYRLIQEVKPDYVLSYTIKPVIYGTL
                     AAWLAKVPHRFALITGLGYAFQNVEQGSSRSFFQKLVHGLYQYALLHSHKVFFQNPDD
                     QQLFRELNLIDHNKPTVVVNGSGVNVQDFTVVEPPKSHSGQLKVSFLLIARLLVDKGV
                     REYAEAAKQIKQSYPETEFHLVGWIDENPTAITQQELDEWIADGRLNYWGKLSDVRPA
                     IEASSVYVLPSYREGTPRTVLEAMAMGRAIITTNAPGCKETVIHGDNGYLVEVRSVQS
                     LLEAMTKLINAPELIEKMSKKSREIALNKYDVDAVNKHMLTEMGLLK"
     gene            16431..17039
                     /gene="itrA1"
     CDS             16431..17039
                     /gene="itrA1"
                     /note="initiating transferase for oligosaccharide
                     synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AHB32263.1"
                     /translation="MIKRLLDILIASTALFLLSPLYIFVAYKVKKNLGSPVLFRQVRP
                     GLHGKPFEMIKFRTMKDATDTQGNPLPDSERLTPFGKMLRSTSLDEMPELWNVIKGDM
                     SIVGPRPLLMEYLPLYNKEQAKRHDVRPGMTGHAQVNGRNAISWEEKFKLDTWYVENR
                     SLWLDFKIMLQTVKKVIAKEDINEAGEATMTKFTGSKSEADK"
     gene            17036..17695
                     /gene="qhbC"
     CDS             17036..17695
                     /gene="qhbC"
                     /note="acetyl- or acyl- transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="QhbC"
                     /protein_id="AHB32262.1"
                     /translation="MNNQVYAIYGASGCGRSLMPVARQQLQRQGISAEIYFIDDSLQE
                     EKLVNGHRALNYQSFKSIDCSNKYVLIAIANSQIREKIANQLVVDGIKLWSIQADNTV
                     IMDNVEISEGAAISPFVSITSNIKIGKCFHANLYSYVEHDCVIGDYVTFAPGVKCNGN
                     IHIKDHAYIGAGAVIKQGTPDKPLIIGKGAIVGMGAIVTKSVPAGVTVVGNPARILER
                     K"
     gene            17724..18899
                     /gene="qhbB"
     CDS             17724..18899
                     /gene="qhbB"
                     /note="UDP-4-keto-6-deoxy-N-acetyl-glucosamine
                     4-aminotransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="QhbB"
                     /protein_id="AHB32261.1"
                     /translation="MLNTAFEPWPSFTTEEADAVKNVLLSNKVNYWTGQECRIFEKEF
                     AEFSDTKYAVALANGTVALDVALKALDIGAGDDVIVTSRTFLASASSIVTAGANPVFA
                     DVELDSQNISRRTIEAVLTPNTKAIICVHLAGWMCDMDPIMQLAAEHGIYVIEDCAQA
                     HGAKYKGKAAGSIGHIAAWSFCQDKIMTTGGEGGMVTTNDEALWKKMWSYKDHGKSYD
                     SIYNKQHPPGFRWLHDSFGTNWRMMEMQAVIGRIQLTRMAEWTKKRTENAEKILKAFD
                     GSPFFSVHTPSVDYVHAYYKCYVQVNLEALPDGWSRDRIMQEINSQEVPCFSGSCSEV
                     YLEHAFDGTPWRPEKRLENAQKLGETSLMFLVHPTLSQDSIEKTILAINAVNRALQS"
     gene            19239..20915
                     /gene="gdr"
     CDS             19239..20915
                     /gene="gdr"
                     /note="UDP-N-acetyl-glucosamine 4,6-dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gdr"
                     /protein_id="AHB32260.2"
                     /translation="MLTGVYRFIVRTFNEAFIAKLAIAVTLMVIVLYSMNAFSPAFVP
                     TSIPLMFGFLMFSWVWCSRAFIRFIVKATLQTGEERKRIAIYGAGDAGQQIAAVLYRS
                     GNHLPVFFIDDNTSLQDHMVGGLKVLSLEKALQRFEKYKTDEILLALPSVGRVRKSEI
                     IQQLEPAHLKITELPGLTQLVDGELKVADIREVDIIDLLGRDPVPPVDHLLAKNIHNK
                     IVMVTGAGGSIGSELCRQIVKNQPKMLIIYEITEFALYSIDKELRLAAQCEIVPILGT
                     VQDQQKLERIIEQYGVQTVYHAAAYKHVPLVECNPIAGLKNNAIGTANSLNAAVKKGV
                     ETFVLISTDKAVRPTNVMGASKRMAELYCQAMAEAQKQTQISIVRFGNVLGSSGSVVP
                     LFKQQIAKGGPITVTHPEVTRYFMTIPEASQLVIQAGALGRGGDVFLLDMGEPVRIQD
                     LARQMISLSGLTVREQGSMQGDIEIHYSGLRPGEKLYEELLIDQENTEYTEHSRILRS
                     FEKFYPLTEIQEVFDRINNMTAVQQDIDWALCQLEHYVDGYKRSKDIMVN"
     gene            21005..21802
                     /gene="galU"
     CDS             21005..21802
                     /gene="galU"
                     /note="UTP-glucose-1-phosphate uridylyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="GalU"
                     /protein_id="AHB32259.2"
                     /translation="MVTVVDRPAIEYVVREAVEAGIEQIILVTHSSKASIENYFDRNF
                     ELETTLEQKKKFDLLAEITQIVPEHVSVISVRQPQPLGLGHAVLCAKSIVGEDDFAVL
                     LPDVLVKDSSGQNDLSRMISRYNSSQAAQIMVEAVPDHLVDQYGIVDVKHSPNEGESI
                     AMQGIVEKPPVGAAPSNLSVVGRYVLPAKIMQLLENTPKGAGNEIQLTDAIAMLQDID
                     TVEAYRMQGQTFDCGSKLGYLKAVLHYGLEHPKLGMEFKQLIQELKL"
     gene            21920..23182
                     /gene="ugd"
     CDS             21920..23182
                     /gene="ugd"
                     /note="UDP-glucose 6-dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="Ugd"
                     /protein_id="AHB32258.1"
                     /translation="MKIAVFGTTLHAGVMAALLAEYGNQIYWCTCVSCEENISVLSYQ
                     DQEVNHYLNKQRKAGFLKESPFSEIPLDIEVYLFCFSPTQIELALKTVEKLSERPIIH
                     PKLMINGSTFGLHGTEKLKQHLPKDEWVYFPDVIQEGNAINSVLDVKHVIVGVESRDA
                     SEIMQELLRPFFQFSYQYLFMPILDAEFTKLSISGMLATRISYMNDLAMVAEKLGIDI
                     ANVKHGIAADTRIGAAYLSPGVGFGGENFSHDILTLSSTVLETGTKSRLLEQVWAINE
                     QQKEILFRKLWNYYHCDLSGKTVAIWGASFKENTSNIHNSPIHILLAALWAQGVKVRL
                     HDPQALDEIASIYGSREDLILCSDQYEAAQNAHALCLVTAWKQYWSPDFKRLQQLMKH
                     PLILDGRNIYDPAYVKARGFAYEGVGRL"
     gene            23179..24849
                     /gene="gpi"
     CDS             23179..24849
                     /gene="gpi"
                     /note="glucose-6-phosphate isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gpi"
                     /protein_id="AHB32257.1"
                     /translation="MSKSIEQFPKDLSSPLIQLKSSVEKNSKLHIKELFALEPERFQN
                     YSVKFDQLFFDYSKQRITKNILEQLVALANNKQLTQWINRLFSQDKINCTEQRAAMHW
                     ALRLPPEYSKFPELTKQVHTQLQRMYALVEKIHAGQYRGATGEVIQDVVNIGVGGSDL
                     GPQMVTHALCDFKVKTAKPLNVHFVSTMDGSQLSDLLHQLRPETTLFIISSKSFGTID
                     TLSNAQTVRQWLEKALGKHDRVVKSHFIGVSTKAEKMTEWGIAPENQLLLWDWVGGRY
                     SLWSCIGFPIALTIGIEGFQQLLAGAHAVDEHFQNTSFEQNIPVLMALLGIWNNNFLN
                     IQTHAVLPYDGRLKYFASYLQQLEMESNGKSIQRDGQKVELDTCPIVWGEVGPNAQHA
                     FYQLLHQGTQAVSCDFIAPIQRYNADHFTYVENAEALIEQHHLALSNCLAQSRLLAFG
                     NEALDVKELEKLPIYKQYEGNQPSSTLLLDELNPYNLGMLIALYEHKVFVQSVIWNIN
                     PFDQWGVEKGKQIADQLLPILNGIQNDFSKLDASTRGLIKILLGKVDG"
     gene            24842..25858
                     /gene="gne1"
     CDS             24842..25858
                     /gene="gne1"
                     /note="UDP-glucose/UDP-N-acetyl-glucosamine 4-epimerase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gne1"
                     /protein_id="AHB32256.1"
                     /translation="MAKILVTGGAGYIGSHTCVELLEAGHEVFVFDNLSNSSKESLNR
                     VQEITQKSLTFIEGDIRNSDELDRVFQEYTIDAVIHFAGLKAVGESQEKPLIYFDNNI
                     LGSIQLVKSMEKASVKTLVFSSSAAVYDEANISPLNEEMPTGMPSNNYGYTKLIVEQL
                     LQKLSVADSKWSIALLRYFNPVGAHKSGRIGEDPQGIPNNLMPYVTQVAVGRREKLSI
                     YGNDYDTVDGTGVRDYIHVVDLANAHLCALNNRLQAQGCRAWNIGTGNGSSVLQVKDT
                     FEKVNGIPIAFEFVPRRAGDVATSFADNCRAVAELGWKPQYGLEDMLADSWNWQKQNP
                     NGYN"
     gene            complement(25900..27270)
                     /gene="pgm"
     CDS             complement(25900..27270)
                     /gene="pgm"
                     /note="phosphoglucomutase/phosphomannomutase"
                     /codon_start=1
                     /transl_table=11
                     /product="Pgm"
                     /protein_id="AHB32255.2"
                     /translation="MTTLTCFKAYDIRGKLGTELNEEIAYKIGRAYGQIYKPKTVVVG
                     CDIRLSSEALKQATIRGLNDAGVNVLDLGMTGTEEVYFAAFHLDVQGGIEVTASHNPM
                     DYNGMKLVRENARPISADTGLKEIQALAETNNFEEVSQKATTQSYNILPEFVDHLLTY
                     IEPAKIRPLKLVVNAGNGAAGHVIDAIEEKFKALNVPVEFIKIHHEADGTFPNGIPNP
                     ILIENRDSTRNAVLEHKADMGIAWDGDFDRCFLFDEKGQFIEGYYIVGLLAQAFLIKQ
                     SGEKIVHDPRLVWNTFDIVDEYKGVAVQSKSGHAFIKDVMREHNAVYGGEMSAHHYFR
                     DFAYCDSGMIPWLLTIALLSETGQSLSTLVENMIAKFPCSGEINFKVADTQTTIQKIF
                     DFYADQNPQIDRTDGVSLDFGTWRFNVRASNTEPLLRLNIESRADRQAQPMQYYVDEL
                     TRLIQN"
     gene            27646..29313
                     /gene="lldP"
     CDS             27646..29313
                     /gene="lldP"
                     /note="L-lactate permease"
                     /codon_start=1
                     /transl_table=11
                     /product="LldP"
                     /protein_id="AHB32254.1"
                     /translation="MTMLNMWQQLYDPLNNIWLSSAVALIPIIFFFLALAVFRLKGSI
                     AGTGTVIIALLIALFFYQMPGQMAFASIIYGFFYGLWPISWIIIGAVFLYKISVKTGQ
                     FEVIRSSILSITEDQRLQMLLVGFAFGTFLEGAAGFGAPVAITAALLVGLGFKPLYAA
                     GLCLIVNTAPVAFGAMGIPIIVAGQVSGVDTMEISQMVGRQLPFLTIIVLFWIMAIMD
                     GWRGVKETWPAVLVGGGAFAIAQYLTSNFIGPELPDITAAIASLVSLTLLFRVWKPKH
                     IFRFEPEAGQTLTQQPTTVQRYSIGKIAKAWSPFAILTVMVTIWSVKPFKALFAKDGA
                     LEHWIFKLEVPYLHKLVEKMPPIVSEIKPYEAIYKFDWFSATGTAIFIAAIITVIFLK
                     MKASEAVTTFGETLNELKTPIYSIGMVLAFAFIANYSGLSATLALALSHTGHAFTFFS
                     PFLGWLGVFLTGSDTSSNALFSALQATTAQQIGIPEVLLVAANTSGGVTGKMISPQSI
                     AIACAAVGLVGKESDLFRFTVKHSIIFTVFVGIIITVQAYLVPWMIP"
     gene            29333..30085
                     /gene="lldR"
     CDS             29333..30085
                     /gene="lldR"
                     /note="DNA-binding transcriptional repressor LldR"
                     /codon_start=1
                     /transl_table=11
                     /product="LldR"
                     /protein_id="AHB32253.2"
                     /translation="MRISDQVVMKLQALIEERHMKKGDRLPAERQLATSLGVSRPSLR
                     EAIQQLNSQGVLISRRGDGTYIQQLPEQWPQQLIVNPISNLIEEDPLYRFDVQEARLV
                     LEGGTAWYAALRSTPEDRAKIHHYFNEISRHQNAGDSAQAAVADAEFHLAIAEASHNV
                     VLIQMMRSLFDLLQYNVLLGRKKVYNDPVNGDLLSEQHFQVMDAIDRKDPEAARQAVC
                     GHIEFVINHVRSLDEDEARQKRANRLNRVDSK"
     gene            30082..31233
                     /gene="lldD"
     CDS             30082..31233
                     /gene="lldD"
                     /note="L-lactate dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="LldD"
                     /protein_id="AHB32252.1"
                     /translation="MIISSGNDYRAAAQRRLPPFLFHYIDGGAYAEYTLKRNVQDLSE
                     IALRQRVLNDMSALSLETKLFNETLSMPVALAPVGLTGMYARRGEVQAAMAADKKGIP
                     FTLSTVSVCPIEEVAPAINRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPV
                     PGARYRDAHSGMSGPNAAMRRYMQSVFHPHWSWNVGLMGRPHDLGNISKYLGKPTGLE
                     DYIGWLGSNFDPSISWKDLEWIREFWDGPMVIKGILDPEDAKDAVRFGADGIVVSNHG
                     GRQLDGVMSSARALPAIADAVKGDLAILADSGIRNGLDVVRMLALGADTVLLGRAFVY
                     ALAAAGGQGVSNLLDLIDKEMRVAMTLTGAKSISDINADCLVQAIKQRL"
BASE COUNT     9495 a   5071 c   6297 g  10370 t
ORIGIN
        1 atggcattat ggcgatcgac ttttattgtc agtgcgatga cgatgttgtc acgggtattg
       61 ggcttagtac gagatgtcgt attgctcaac gtgtttggtg cgggtaaaga tttcgatacc
      121 ttcgttgtgg cttttcgtat tcctaacttc tttcgacggt tgtttgccga aggggctttt
      181 tcacaggctt ttattccggt attgaccgaa tataaaacag gtcgtgcgca tgcagaagtt
      241 caaatcctga ttagtcgggt atttggatgt ttgctgacag tcatgacctt actcactttc
      301 gtggctatgg ttttagctcc agcaattatc tatatgtatg cgccgggttt tcataatgac
      361 cctgaaaagt ttgatttagc ggtcagtatg ttccgcctga ccattcccta tttaatgttt
      421 atgtcgctta cggcttttgc cagtagcatc ttaaacagtt atggctcgtt tgcctcgcca
      481 gctttttcac ctgttttact gaacgtagca atgattgcag gggcttggtg gcttacaccg
      541 tatatggctg agccaatcaa agctttaggt tggtcagttg ttgcggctgg tattttacag
      601 ttagcgatac aaattcctga gttatggcgt aaaaacttac tgatcccacc gaaagttgat
      661 tttaaacatg aaggtgtaga acgtatttta aaattaatgc ttccagcatt atttggtgtc
      721 tctgtgactc agattaacct attgctaaat acgatttggg catctttcat gcaagatggt
      781 tcagtgtctt ggctctacag tgccgaacgt atgaccgagt tacctttagg attaatcggt
      841 gttgcgattg gtacagtgat tttaccttca ctgtcagcac gtcatgctga acaagaccaa
      901 gcgaagtttc gtagcatgat tgattgggca gcgaaagtga ttgtattggt ggggttacca
      961 gcaagtattg ctttatttat gctttctaca ccgattattc aggcattgtt ccaacgcggt
     1021 gagtttgatt tacgcgatac acaaatgaca gcactcgcat tgcagtgtat gagcgctggt
     1081 gtaatttcct ttatgttaat taaagtattt gcaccaggtt tctatgcgca gcaagataca
     1141 aaaacaccag tccgtgtggg tttaatgtcg gttgctgcca atgcgatttt aaacgttgta
     1201 tttattggat tttttaaact aatcaattgg catgcagagc atatggcgct tgcattagcc
     1261 tcctctggtt cagctttagt aaatgcaggt ttgctctatt tttatctgca taagcgtaat
     1321 attttccgat ttggtgcaca ttggaaaaaa ctggcacttc aatatggctt ggccaacctt
     1381 gcgatgattg cagcgctttg gttcgggtta aattggtata acggagagct ttcacagtgg
     1441 ttacgtgttg ccgaagtggt tggattgtgt gtggttggtg tgattgccta tgcaatcggt
     1501 ttatttgcat ctggatttag accgaggcat ttaaaggctt gatatatatg tgtatagtta
     1561 agactataca ctataataaa taatatgaag agaagatgta agccatttat acaaaatact
     1621 atagaatttc tgagtgtagc ctgagatcat aagtaaattt tttgagaatg tccttatgaa
     1681 tttagctcct tatacatcat tcccgtgctt aataattatt tcctcaattg cttttgctaa
     1741 tagtaatctt tttcaagata atatggatat tactgattta gttaataata aaataaaaga
     1801 aaactcttta ataaaaattc cagcggggaa ttttaaaatt aatgcagaaa agtcaattat
     1861 tctaaaaaat aatgtcacta ttgagatgag tcctaaaaca gttttaaatg ttatacctaa
     1921 tgaggcaaat agctatcaag tttttaaaat tcataatgta aataatgtta gaatttcagg
     1981 tggaacaatt ataggggata aatatactca tcgaggtact aaaggagagt ggggtacagg
     2041 tattgaaata aaagattcac aaaatatata tttatctaat attattatta aaaaaatgtg
     2101 gggagatgct atttatattg gtaataatgg aaaaaactct aactctaact taaacttaat
     2161 taacttaaaa ttagatgata atagaagaca aggaattagt atagttagtg taaatggttt
     2221 gtttgctaat aatataataa tatctaacac tagaggtaaa agccctatga gtgggatcga
     2281 tattgaacct aacaataata gaaatatttt gaaaaatata aaattttccc agataagtac
     2341 agttaataat gctggtgatg gatttcaaat ttctttaaaa aaatacaata attctatgca
     2401 aggagtctca ataagtttaa gtgaatataa tgattatggt tctagatctg gtattagaat
     2461 tcaaggatta aaaacacctg ttataggtga gataaatatt aacaaagtca atttaaaaaa
     2521 taataagatt tcaaactatt gttttaagga ttgggaaaat aataaggtta agattaaaat
     2581 tacaaatctc ttgcatgata aggaatatat aaaaaatcaa gataaatggt gttcacctta
     2641 tactaacaat gatttcttga aagtagtaaa aagagataat taattatctc tttttactta
     2701 tcagacaaaa tattttactt ataaaatttt aattaattca atatcaaaaa taagggtact
     2761 atttggacca attgcatcac ctgcaccgac ttcaccgtaa gcgagatttg cagggataaa
     2821 gaaacgagtt ttaccgcctt ctttcatagt ttgtaagcct tcagtccatc cggtgatcac
     2881 ttgatttaac tggaaatcaa cagggtgatt acgtgcaatt gagctatcaa atacagttcc
     2941 gtcgagtaaa cgtccttcat agtttacttt tacacgagaa gtggctttag gtattttacc
     3001 agtaccttct tttaacacct gatattgcag acctgattta gtcgtaatca caccagattt
     3061 tttagcattt tctgccagaa aagctgcacc agcttgagcg ttttgttgac cttgtttttg
     3121 aaattcgact agctgtttag cttctaatgt ttttttataa tcattaattg ctttcgccat
     3181 ttcttcatca gttaggcgtg ctgtcttatt ttgagcacct tcttgtaaac cttggtaaaa
     3241 aatatcaaga tttaaatctg ttaacgcatc agtattatta cggcccatta aataaccata
     3301 actataacta aactgatctt ttgccggact tttatttgtt atcggtgcag cagcaaaaac
     3361 agataaactc atcgttgacg ctgcaataac caaactgatt tttttcatgt cattttccaa
     3421 aaaaaacagg agagtataac gactctcctg gattgttatt atttcactga aatgagttct
     3481 acatcaaaaa tcagtgtact gtttgctgga attccaggaa gctcttgtgg gccatatgca
     3541 agatttgatg gtatgaagaa agtcgctttt ccaccttctt tcatgagttg aagaccttca
     3601 gtccaacccg gaatgacctg attaagcggg aattctactg gttgaccacg cttataagaa
     3661 ctatcgaaaa cctgtccatt aattaagcgg ccttcataat gtactttaac aatagactga
     3721 gcagttggct gtttaccagt accttcttta gtaatgatat attgcaaacc tgatgcagta
     3781 gtttttacgc cagctttggt tttgttttct gcaaggaact gtgcatctgc agagtcagta
     3841 gccgtacctg attgctcagg tttgtcttga tgctgcattt tttgttgtaa ctctttttca
     3901 taagcagcaa cggcagcttt taaatcttct tgagtataag cactaggctg cttattacgc
     3961 gcatcatgga tcccttgaac aaatgctttc gtatccagtt gaggaggggt ttgctgagca
     4021 acttcatacc caagaacata actgattttt tgaattggag aagcattttt gtctgcttta
     4081 cgtccgactt ctgtggtcgg atgttgagtt gcataatata caggtacaag tgcagcaccg
     4141 cctaaaacta cagcgacagc aatgggtaag gctttactca taaagggttc caaaaataat
     4201 catttgagtc taaaaggctg cttcgatctt agcatgcttc gacttaagca tagaatgttt
     4261 aacaaaaaaa acgagtggtt ttttatatat tttagttagt tttaatgtgg caaaacttaa
     4321 aaagcaaata aaaaaccgga tcatttgatc cggtttttat gaagagtttt aattagtctt
     4381 ctttttgtgc cttataggca taagcatagt tatagccata accatagcca gcgctagcac
     4441 gttgaatatc attgagaata aagccgttga ctttaacacc cgcttgttca aaacgattaa
     4501 cagttagttc aagctctttc atttgtgact tggcgtagcg tgcaacaatt aagttcacac
     4561 cagtatattg cgaaataata ataccatcgg ttactgcaag tactggtgga gtatcaataa
     4621 tgatgtggtc gtattggctt tgtagctgct caagtaattc cttaaactga tttgagctta
     4681 aaatctctga aggatttgtt gggctcttac cacgagtaat cacatcaaga ttatcaactt
     4741 gtgttttgtg caatactttt tgtaaatcag cttgtccact taaaaattct gataggccag
     4801 gcttcacctc aacatcaaaa tatttatgta tataaccacg gcgcatatcg gcatcgatca
     4861 ataatactcg tttatcgcct tgcgcaaaaa tagttgcaag gttggttgaa ataaacgatt
     4921 tacctacttc tggtgaagga cctgcaatca tgatgatatt attttttgca tttgctaatg
     4981 caaagtgaat cgcagtacgg atactacgta aactttcaat tgcaatatcg tcactatttt
     5041 taatcgcaag aatagggata ctcttcttct tctttaaaat cttgatacgg ctttcttgga
     5101 ttggcgaacg agggacagtt gcataaactg gtaagtccag ttcattttca atttgcccag
     5161 aatctttaat acctgtacgt agcatattac gcaaaagagc aattaaagta ccaataaaac
     5221 cacccaagaa aatagataaa attaaaattt gtaatttttt aggtttaatt ggttcaattg
     5281 gctcaacagc agtatctaca atacggacat ttccaatttc acctgcttta gcaatacgaa
     5341 gctgttggta tgagtttaaa agtgctgtat agagctgagt cttcacctct acttcacgat
     5401 ataattgtaa gtattgacgt tgtacgtctg gtaactgttt taacgtgcta ttgagttcgc
     5461 caatttgctt attaatagca gaaagttggc cattaatttc acgcattgca ggatgctcag
     5521 ccgtatattt agctgccatt tcagcttgtt tttgttcaag ctcggctttt ttggtttcta
     5581 aggtaatact ttgagtcaaa taaagttcag actcttttgt cacatcaaca gtattgtatt
     5641 gctggcggaa tttattaaat tgacgctctg catcatctaa ttgtttttta agatctggta
     5701 gttgctcatc caaaaatttt aaagtttgag cagattctgc tgagcggcgt tcaatatttt
     5761 gcgcgctata agttgctaaa attgcattta aaactttagt aatgtgctct ttgtcttgac
     5821 cttgataatt taagcccaaa actccagtaa gtttgccgcg ttcagctaca gagtattttg
     5881 aactaatcgc atttacagca gcaggaacag ataggttttt aatattataa gtggtattaa
     5941 actgatcttt agtaaaaata ccgactttcc aagtgccata tggaccagtg acttggttta
     6001 gctgattaag tggtatcgtt aaaagagttt gttccgttgc tgggtcagtt aaacgtacag
     6061 attgtttatc aaagttaaga tgtaaggtct tatccaaata ataggctgga acttctaatg
     6121 tacgaatctc aaaacttttg agaccgtcct taaagataac tgatttttta gagtattcag
     6181 ttttatagtc agtatcgctt aataagcgat ggctaaaagt attttctgta ctggaaactt
     6241 gtatattcag atgtaattct ttaatgacag aacccagtac caaccgagat tttaaaattt
     6301 caatttcagc ttgagcaggt gatttttgct ctatcatatt tgataaatca ccaagtaaag
     6361 ctgcagaagc tcctttacta tcttctacct gaacaagagc atcaactgaa taggtgtttg
     6421 gagttacacg taagtagatt aaagcacata caagacttaa aataacgcag agtgcgataa
     6481 gcttccactg tgcaatgagt gaaaaaaaca attcttttaa atcgatagta tcttcgatat
     6541 tggtattttg gttcataagc ttaaaatctt ggcgttaaat ataaggtttc cagtcagcta
     6601 tacactgttg aataagttgg caggtttcat caaaaaaggc ttgatcatgc tgatatggat
     6661 ctggcacatt tctgttttgc caatgtccta gacgatacgt ttttcctttc gcaaagggcc
     6721 agttttgttc aatatgtttt tgctgattat ggctcataac caaaacaagg tcagcttttt
     6781 taatgtgttc tgcactaagt ttacgggcaa tatgaggttt catatcaata cccaaacgtt
     6841 gcatacaaag ctgggctttt tcatcagctt gatgaccaat aagccctgag ataccagcag
     6901 actcaatatt taattgggga tattgctgtt ttaagaaata ctctgccata ggacttcggc
     6961 aaatatttcc aatacaaact accaaaatat ttttaatttc cataagctta ttgtcccaaa
     7021 cggtctatat tatataaagc atttgagaat ggaatgacct gattaactac acgttgccaa
     7081 cgagttagac cagttgcatc gacataaaca acatcattac tacgtagttt aaactgatta
     7141 gctaaaccga aatcgcccag actcattaaa tttaagtgat aaattgcagt ggtatggtca
     7201 ttttgatttg ttcgcactac ataaatacga ctggcgcttg cagataaagg attaatacct
     7261 aaactttcgc ccagtgcatc ggttaaagtc atgccttggt cacgcattgg tagggcttgg
     7321 tttttaccag actcacccat cacataaatt ttttgatttt cgcgtgtact tacataaata
     7381 gtgtcattag gttgaaccaa aagtttatga agtgaataac ctgctttttc tagatcaatc
     7441 gtatttagat tataggttcg gccattacga atgagttgaa tataagtatt atcgccttta
     7501 tcacttacac caccagcaag acctagtgca gtatatatac tcacaggttg atcacttaag
     7561 taaaactgtc cacctttggt cacactacct tgaacagaga agcgctgccc ttcatatgaa
     7621 agtacgcgaa caatcacatc tggatttttt aagaaacggg cgagctgact acgtaattcg
     7681 cggtttactt gagtaagagt tttacctgca gctttatagc ggccaactaa tgggaattga
     7741 atatagccac tttgatctat agggtaacca tttgcctgta cagactgttc attattaacg
     7801 ttatttactg gaggcgtaat ttcagggtat gcccaaagtt gaattgaaag tacatcacct
     7861 gagcttaaac ggtaaattgg ttgctgattt ttaaataggg ttgcatagtc gcgctgatag
     7921 tcgacttgag ctggttgtat cgcaggcaat gattcttgcg agatttttac aacatttact
     7981 gttgttccga gctcggttct ataaacacct tcacttggaa catcataagt ttgtaaaccg
     8041 gaagtaaccg cacagctggc agcacttaga cttaaagcaa gaacagaaaa aaactgacaa
     8101 tacttcacaa gcaacccttt gtgtatttat ctttaattga tactgtctgt atcgttaatg
     8161 gtatagcatt aaatgcttat attagacaga gatggtccga ttctagctga aaagaaatta
     8221 aaaaacaccg aaaaatcgta tagctttgta tgtttaattt atatcagcgc accttatcac
     8281 atatgaatta ataaatatta tttaatcaac ggttcaataa atatcctagt caggttgctt
     8341 aaacagagct taacaactgt aaacactttt atacaattga attacggtta ataaaaaaaa
     8401 actgatatag ttatgcacga cgatattcgt tcaccatgta tcattattta atatatacaa
     8461 tttgtaagga ataaggctaa cttttatgca acttgccgat ttaagaatag cgattatagg
     8521 tttaggttat gtaggcttgc cattggcggt tgaatttggt aagaaggtac cagttgttgg
     8581 atttgatatt tatcagaaac gtgtagacga acttaaaaat ggtcaggatc atacgctaga
     8641 agtttcgcca gaagaattaa agcaagcaac tcaactgagc tatacggcaa atttagaaga
     8701 attaaaagac tgtaatttct ttatcgttac tgttccaact ccgattgatg attataaaca
     8761 acctgattta acgcctcttg tgaaggcttc taccagtatt ggtaaagtac tcaaaaaagg
     8821 tgatattgtt gtttatgaat ctacagtcta tcctggggca acagaagaga cttgtattcc
     8881 cgtccttgag caagtttcgg gtctgaaatt taaccaggat ttttttgctg gttatagtcc
     8941 agagcgtatt aatcctggtg ataaattaca ccgtgttacc aatattttaa agatcacatc
     9001 tggttctaca gcagaagtag ctgaatttgt ggatcaagtt tataacttgg ttattgaagc
     9061 tggaacacat aaagccccaa gtatcaaagt agctgaagct gctaaagtga ttgaaaacac
     9121 acaacgtgat gtcaatatcg cattgattaa tgagttggcc gtgatcttca ataagatggg
     9181 catagatact gaagcagtac ttgaggctgc aggtactaaa tggaacttct tgccattccg
     9241 tcctggtttg gttgggggac attgtattgg ggttgatcca tattatttaa ctcataaagc
     9301 ccaagcaatt ggttatcatc ctgaaattat tcttgcgggc cgtcgtttaa atgacaatat
     9361 gggtgcatat gtcgtaactc agcttgttaa aggaatgatt aaaaagaaaa ttcaggtaga
     9421 aggcgccaaa gtcttaatct taggcttaag ttttaaagaa aactgcccag atattcgcaa
     9481 tacaaaaatt attgatatag tagctgagct aaaagagtac gagacacaag ttgacgtgta
     9541 tgatccgtgg gtggaccgtg cagaagctga gcatgaatac gggattacac cagttcagtc
     9601 agttgaaaag aatacttatg atgctgtgat tttagcagtt gcccatgagc aatttaaaga
     9661 aatgggcgct gctgctatcc gtgctttagg taaaaataat catgttttat atgacttaaa
     9721 atatgtttta tctcaagcag agtcagatat ccgactataa atcataagga aattaaagat
     9781 gagtcaatat caaacagtat gtgagcaatt aaaacatcag ccaaaaacgt ggttaatcac
     9841 tggcgttgct ggttttattg gctcaaattt acttgagacc ctattaaaac tagaccagaa
     9901 aattgtcggt ttagataatt ttgccactgg tcatcaacat aatttagatg aagttcaagg
     9961 tttggttacg ccagagcagt gggctaggtt cacatttatt caaggtgata ttcgtaatct
    10021 tgaagattgt caaaaagcgt gtgcaaatgt tgattacgtt ttacatcaag cagcattagg
    10081 ttcagttcct cgctctattg ccgatccgat tacaactaat gcagcgaata ttacaggttt
    10141 tcttaatatg ttagtggctg ctcgtgatgc acaggtaaaa agttttacct atgcagcaag
    10201 tagctcaact tatggtgacc atcctgcgct tcctaaagta gaagaaaata ttggtaatcc
    10261 attatctcca tatgcggtga ctaaatacgt caatgagttg tatgcagatg tgtttactcg
    10321 tacttacgac tttaaatgta ttggattgcg ttactttaat gtatttggaa agcgccaaga
    10381 tccaaatggt gcgtatgcgg cggtaattcc aaagtggacg gctgcaatga ttcaaggcga
    10441 tgatgtcttt atcaatggtg atggtgaaac cagtcgagat ttctgcttta tcgaaaatac
    10501 agttcaggca aatattttag ctgctactac tgaaaatgaa gaagcaaaaa atcaagttta
    10561 taatgtcgct gtaggagatc gaactacctt aaatgattta tttaatgcaa ttaaaaatgc
    10621 cttaaaagaa aatcagatta tgtatgttaa agatcccatt tatagagatt ttcgtaaggg
    10681 agatgtaaga cattcgcaag catctgttga aaaaattcag aatttattag gttacaaagc
    10741 ccaatatgtt atttctgaag gcgttgattt agcaatgaag tggtatgtaa agaatatttc
    10801 atgaatcctc gattgttaat aagcaaatat aaatcgattg gtgttattac atcaagttta
    10861 ttggttggtg cgataataac ttttatcgca cttcctatat taacacgttt gtatagtgta
    10921 aaagactttg gacaatatgg cgtagcatta gctatcgtta gtgtaatgtc aactattgct
    10981 aatctaagat tggatcaagc aatattaatt gcacaagctg aagaaaaaaa aagtttaatt
    11041 tttgaaagta tattgttagc tattttattt tgcataattt cgtctggagt tatggtattt
    11101 atctttaatc cattaatgat atttgcaatt aattttggag tgttggctaa tatcttcatt
    11161 caatgtattt ataattataa tttttctata gagaatgaat atttttgtgc ttgtctaaat
    11221 atacttcgca gtctagttgt tgttattatc caaatttctt tcccattttt ttataatgca
    11281 aacctacttg caagctattt aataagctct ttattcataa ttttattatc attgagttat
    11341 atatttaaat ataaaatata tagagttggc ttttctagct ttaaggggta taaagacttt
    11401 attttctcta atactcccca tgcattatta aatagttttt cacataactt gccatattac
    11461 gtagtttcac attttttaag ttatcaagtt gctggttttt attcaattgt agagagaaca
    11521 cttagattac ctattaattt aatgtcacaa actataagac aattttttat tcggaaattt
    11581 aatacaaaag gtgattatag agaggcatta aaaagtagtc tttttttaag tttagtgtct
    11641 ttacctttct ttttaatatt ttttgcttta cctgaatctc tttattcatg gatctttggt
    11701 agtgagtgga atggtatctc tacatatttt aagattctta ccttgggata ctgggccgtt
    11761 ttttgtaatc ctccaatttc aggattttta attgctaaaa gaagaagtga tatattatta
    11821 aagctacaga ttgtagagtt aattattaaa gctttgttct ttacacttat ttatagctta
    11881 ctggatgata aaaacagcat gttatatgca attccattaa gtctaatttt ttataatttt
    11941 tctatttatt ttgctgtagg gaagatgaaa aaatgttgat tctgaaattt atgaagttat
    12001 tttcgatttt tttcacttca tttagaacac ttttttatag ttctattttt agaacaaaga
    12061 ttaaaaaaat tggtgtaaat gttacctttg atataaatgg aaaaattgat ttagggaaaa
    12121 atttggttat agaaagtggt gctactatta ttgttgagaa aggtgccaaa cttcaaatag
    12181 gtgataatac ttttatagga gaaaatactt atattaaatg ctatggtgga agtatccaga
    12241 ttggtaataa tgttagtatt aattcaaaat gttttttaaa tggtgcgggc ggattattga
    12301 ttggtaataa cactagaata ggcacacagt ctattatgat atcaagtaat catatatttg
    12361 aaagatcaga tgtcttgatt aaagatcaag gcacaagcag agaaggtatt actataggcc
    12421 aagatgtatg gtttggagct cgcgtaacgg ttttagatgg cacctttatt gttgatcgtg
    12481 tagtggttgg agcatgtagt ctaataaata aatctatttt agagaatgga gtctttgttg
    12541 gcatccctgc taggaaagtt aaagagattt gacgttgagt atgaatagta tgatgataaa
    12601 taaaagatta ataatatatt gtataatttt tatattctta tgtttgttct caatatttcg
    12661 ttttgaggat ggtaaggttg gtgactttct tgttactaat tatgatgaac tccgttactt
    12721 gttagctact gataatatta ttcaagacac aaaagtgtat ggaataattt ataccttaga
    12781 aaatttttat aattatacgc aaagtgtaca ttttttacat tattttgttt tgtctttttt
    12841 tagatatttt tttaatgact ctatggtcgt ttggagttta taccaattat ctatatatac
    12901 attaggttgt tatttttttg ggaagtttat tcgcttagag tatgatttta tctcaactaa
    12961 tgaggagttt ttggcaacgg tgttaatgtt gctttatcca gtattttatt tcctaacatt
    13021 ttccttaatg cgggatattg ctatattttc acttttatct atttgtcttt atttttataa
    13081 atcaaataat tataagttgt taattctatt tatttttgta atttccttgt atagattaaa
    13141 tatgatgtta tgtattttgg tctatattct cattgatcag tttagagata gaagtatact
    13201 atctatatta aaatatttga ttttatcagc gctaatttta ttcgtggtgg ataaggtttc
    13261 tattaatttt ttatctagac atttaagtcg aatttatgag tttaatttct tagggttaat
    13321 aaatgaggtt ttagtttttc ttttatctcc tttaccattt tctgtcgatc aatcattgcc
    13381 acaatattta aggttttggt ttatgatatc attttggtta tgtgtttttt taatttttat
    13441 ctatattatt tttattataa aaaagaaaaa tattcaactc gtcttaggtg caccaattat
    13501 aggtatgagt ttgttctata tagctacgta tagtattgaa gctggtatcg ggtttagaca
    13561 atcatcaatt cttctcccat ttatttatat tccaatattt ttgtacttta ttaagcaatt
    13621 tattcccgtt aaaagttatg taaattttaa aggtaccaat gaatgaataa gttaatacga
    13681 atttttaatt atttatatga tatatatttt tttattaaaa aaggaagtat taagtatgct
    13741 agacgaaaag gtgtaaccat aggtaatgac tgtagaattt atattaaaga atgggggtct
    13801 gaaccttttc taattactat tggtgataga gtaactatca cttctggtgt gcgactagtt
    13861 acacatgatg gaagtacatg gctagttaga gacgaaaata atagtagata ccaaaaatat
    13921 gcacctatca caattgggtc gaatgtattt attggcctaa atacaattgt tatgcctgga
    13981 gtaacaattg gagataatgt agtagttgga gcgggtagtg tagttacaaa ggatattcca
    14041 ccgaatagta ttgcggtggg gaatccagcc cgtgttattt caacatatga taaatttcat
    14101 caaaaaattg aaagctcttg tgtaaataat agagaaattc agcatattgt tgattataaa
    14161 gagcgtgtat ataaagctat tgaaataggt aagtctagag atggtaaata atcacctttt
    14221 tgtttttcca acagcaattt taggtggtgc agaacgtgta atgttcaata ttatttacca
    14281 cctactgtta caacagcaaa atgttactgt agtgattatg tctcgcggta aacaaaatgg
    14341 ttgggagcga ttacaaagct ttcctaattt agacttaatt atttatgatt acgcttcaga
    14401 gaaaaaagct attcttccgt tgatcttagg attaatacag ttaagtatga agtgtaaatt
    14461 taatctttta ttttcttcac atactcatat taatggttta ttaagttttt tgaaaaagat
    14521 tggttttttt agggggtcta ttcttgtctc tagagagtca acgtttattt ttgatagatt
    14581 ttttggtata aaacgattta tctttaaatt tatttataga tttttttacg gacaacagaa
    14641 cttaattatt tgccaaaccc aaaaaatgaa aaactcatta gagagtgcac taggttatat
    14701 acccgggaaa gagatggtgg ttatacctaa tcctgtaaac attgactata taaaatcatc
    14761 tatatcaact gttgaaaaag ataatattat tgtaggatgt ggacgtttta tcccattaaa
    14821 aaaatttgat tttttactac aagcatttga gcaactagat agtaaatatg cacactataa
    14881 attagttctt attggagaag gacctgaagc tgaaaaatta gaaaaaatgg cgaaagattt
    14941 aggtgttgca gaaaaagtta tatttactgg aaaaattaat aatccaatac agtggtttgc
    15001 aaatgcaaga gtaggggtca tctcttcaga aatagaaggt tttccaaatg tccttattga
    15061 aatgatggct tcaggtattg attatgctat ttctacgcct tgtacagatg gcgtatatga
    15121 gttacctaat ataatagtaa cagctgattg ttctattggc gaaataaaga aagctttgga
    15181 gcgagcatta gaacatcaat tgagttactc agaagagtat aaagaatata ttaagaagga
    15241 gcggtcagtt gcttcatttt gggatagagt tttagagctt acaaaatcat gaaattttta
    15301 cttatagcga gttacctccc atcagttttg aattttcgtg gaaagttact tcaagctatt
    15361 caaagtcaag gttttgaaat tcatattatt gcgcctgatt tgagattatt taaaacagaa
    15421 caacaggagt tggaagcttt aggctatcat atacatgaaa taccaatgca acgtaccggt
    15481 actaatccaa tcagcgacct taaaacatta tgggcaacat atagactgat acaagaagta
    15541 aaaccagact atgtattatc ttatactatt aagcctgtta tttatggaac cttagctgca
    15601 tggctagcca aggttcctca tcgtttcgcg ctgattactg gacttggtta tgcatttcag
    15661 aatgtagagc aaggtagcag tcgcagtttt tttcagaaac tcgtgcatgg actatatcaa
    15721 tacgctcttt tacatagcca taaagtcttc tttcaaaatc cagatgatca acagttgttt
    15781 cgggaactaa atttaattga tcataataag ccaactgtag tagtaaatgg ttctggagta
    15841 aatgttcagg attttactgt ggtagagcca cctaaaagcc attctgggca gcttaaagta
    15901 tcattcctac ttattgcacg tttattagta gataaggggg taagagagta tgctgaagca
    15961 gctaaacaga ttaagcagtc ttatccagaa actgagtttc atttagttgg atggattgac
    16021 gaaaacccaa cagcgattac tcaacaagaa ttagatgagt ggattgctga tggtagacta
    16081 aattattggg gcaaactttc ggatgtgcgt cctgcaattg aagctagctc tgtatatgta
    16141 ttaccttctt atcgtgaggg aacacctcga acagtattgg aggcaatggc aatggggcga
    16201 gctattatca caaccaatgc gccaggctgt aaagaaaccg taatccatgg cgataatggt
    16261 tatttggttg aagtcagatc tgttcaaagt ctgttagaag cgatgacgaa gttaattaac
    16321 gctcctgagt tgattgagaa aatgagcaaa aaatctcgtg aaattgcctt aaataaatat
    16381 gatgttgatg cagtcaataa acatatgcta acagaaatgg gattactaaa atgatcaaac
    16441 gtttattaga tattctgatt gcctctactg cattattcct tttatctccg ttatatattt
    16501 ttgtcgccta taaagtaaaa aagaatttag gttcgccggt attgttccgt caagttcgtc
    16561 ctggtttgca tggtaagccg tttgaaatga ttaagtttcg gacaatgaaa gatgcaacag
    16621 acacacaagg taatccttta ccagacagtg agcgtttaac accatttggt aaaatgttgc
    16681 gttctactag tctggatgaa atgcctgagc tttggaatgt tattaaaggt gatatgagta
    16741 tagtagggcc aaggccttta ttgatggagt acttaccgct ttataataaa gaacaagcaa
    16801 agcgtcatga tgtacgtcca ggaatgactg gacacgctca agtcaatggt cgtaatgcaa
    16861 ttagttggga agaaaaattt aaactagata cgtggtacgt tgaaaataga tcactttggt
    16921 tagactttaa aataatgctg caaaccgtta aaaaagtaat tgctaaagag gatattaatg
    16981 aagctggcga ggcgacgatg acgaagttta caggttcaaa gtcggaagca gataaatgaa
    17041 taatcaggtc tatgctattt atggtgcttc aggctgtggt cgtagtttga tgcctgttgc
    17101 aagacaacag cttcaacgtc aaggtatttc agctgaaatt tattttattg atgatagttt
    17161 acaagaagaa aaattagtaa atggccatag agctttaaac tatcaatctt ttaaatcaat
    17221 agattgctca aataagtatg tattaattgc gattgcgaat agtcagattc gtgaaaaaat
    17281 cgcaaatcaa ttggttgttg atggtattaa actttggtcc atacaagctg ataacacagt
    17341 aattatggat aacgtagaaa ttagtgaagg cgcagccata agtccttttg tttcaattac
    17401 atcaaacata aaaattggta aatgttttca tgctaattta tacagttatg ttgagcatga
    17461 ttgtgtgatt ggcgactatg tgacttttgc ccctggcgtt aaatgcaatg gtaatattca
    17521 cattaaagat catgcctata ttggtgctgg agctgttatt aaacaaggta cacccgataa
    17581 gcctttaata attggtaaag gtgctattgt tggaatgggc gctatagtaa cgaaaagtgt
    17641 tcctgctggt gtaactgttg taggtaatcc tgcaagaatt ttagaaagaa agtaagtaag
    17701 aaatatttta ttaggaagtt aaaatgttaa acactgcatt tgaaccatgg ccaagtttta
    17761 caacagaaga agctgacgca gtcaaaaatg tattactatc aaataaagta aattattgga
    17821 ccggtcaaga gtgtagaatt tttgaaaaag aattcgctga gttttctgat acaaaatatg
    17881 cggttgcttt agcaaatggt accgtggctc tagatgtcgc attaaaagct ttagatattg
    17941 gcgcgggtga tgatgttatt gtgacgtctc gtactttttt agcttcagca agttcgattg
    18001 taacagctgg cgctaatcct gtttttgcag atgtagaatt agattctcaa aatatttcac
    18061 gtcgtactat tgaggctgta cttacaccaa atactaaagc cattatttgt gtacatttag
    18121 ctggttggat gtgtgatatg gatccgatta tgcaacttgc tgccgagcat ggtatatatg
    18181 ttattgaaga ctgcgcccaa gctcatggag caaaatataa aggtaaagca gcgggctcta
    18241 ttggtcatat tgcggcatgg tcattttgcc aagataaaat tatgacaact ggtggtgagg
    18301 gcggtatggt caccacgaat gatgaagcgc tttggaaaaa aatgtggtct tataaagatc
    18361 atggtaaaag ttacgacagt atttataata aacagcatcc accaggtttc cgttggttac
    18421 atgactcatt tggtactaac tggcgtatga tggaaatgca agcagtgatt ggccgaattc
    18481 agctaacccg tatggctgaa tggactaaaa aacgtactga aaatgcagaa aagattttaa
    18541 aagcctttga cggctctcct ttctttagtg ttcatactcc ctctgtagat tatgttcatg
    18601 catattataa atgctatgtc caagtgaatt tagaagcctt gccagatggt tggtcacgag
    18661 atcgcattat gcaagaaatt aactctcagg aagtaccttg ttttagcggg tcttgttctg
    18721 aagtttattt agagcacgca tttgatggta caccatggcg cccagaaaag cgtttagaaa
    18781 atgctcaaaa attaggtgaa accagtttaa tgttcttggt tcatccgact ttgagtcaag
    18841 acagtataga aaaaacaatt cttgcaatta atgctgttaa tagagcttta caatcataaa
    18901 aatgtgaagc tattcacata gctttctttt gaattatgat ctgatttaaa gttatgtaac
    18961 cgatgcgtaa aatttatttc tagttatact agaaatgagt ataaataccg cacggttact
    19021 agaacgatta gaagagtatt gtgaaaaaga ttatttatca gtttgcgtca gctcctcggc
    19081 ttacaaaaca atgttttttg gttcttatcg acctattcac ttttcctgtt attttatggc
    19141 tgtgttatgc catccgatta tttgatttag gtgctgaggt tattccaggc attaactatg
    19201 gcgtggcgtt tgttacaatt ttagccatcc taagcttaat gctaactgga gtttatcggt
    19261 ttattgtccg tacttttaat gaagccttta ttgctaaatt agcgattgcg gttacattga
    19321 tggtcattgt tttatatagc atgaatgctt tttcacctgc atttgttccg acttcaattc
    19381 cattaatgtt tggcttctta atgtttagtt gggtgtggtg tagtcgtgca tttattcgtt
    19441 ttatcgtaaa agctacgtta cagactggtg aagagcgtaa acgaattgcc atttacggtg
    19501 ctggtgatgc tgggcagcaa attgcagcgg tgctttatcg ttctggtaat catttgcccg
    19561 tttttttcat tgacgataat acatctttac aagaccatat ggttggtggt ttaaaagtac
    19621 tatctttaga aaaagcttta caacgttttg aaaaatataa aactgatgaa attttactag
    19681 cattaccttc agtaggccgt gtacgtaaaa gtgaaattat tcaacaacta gaacccgcac
    19741 atctcaaaat tactgaactt cctggtctta cacaacttgt tgatggtgaa ctaaaagttg
    19801 cagatattcg tgaagtagac attattgact tactgggacg tgaccctgta ccacctgtag
    19861 atcatttact tgcaaaaaat atccataata agatcgttat ggtcactggt gcaggtggat
    19921 ctattggttc tgagttatgc cgtcaaatag tcaaaaatca gccaaaaatg ttgattattt
    19981 atgaaattac agagtttgcg ctttatagta tagataaaga attacgttta gcggctcaat
    20041 gtgaaattgt tcctatttta ggtacagtgc aagatcaaca aaaattagag cgtattattg
    20101 agcaatatgg tgttcagacc gtttatcatg cggctgctta taaacatgta cctttagttg
    20161 agtgtaatcc aattgcagga ttaaagaata atgcgattgg tactgcgaat agtctaaatg
    20221 cagctgtgaa aaaaggtgtg gaaacgtttg ttctaatctc gacagataaa gcagtacgtc
    20281 ctaccaatgt aatgggtgca tctaaacgta tggcagagct ctattgtcaa gcaatggctg
    20341 aagcccaaaa gcaaactcaa attagtatcg tccgttttgg taatgtatta gggtcttctg
    20401 gctcagtagt gccgttattt aaacagcaaa ttgctaaagg tggtccaatt actgtgactc
    20461 atccagaagt aacacgctac ttcatgacta ttcctgaagc atctcagttg gttattcaag
    20521 ctggtgcgct aggtagaggt ggtgatgtgt ttttacttga tatgggtgaa cccgttcgta
    20581 ttcaggattt agctcgccaa atgatttctt taagtggttt aactgtgcgt gaacaaggtt
    20641 caatgcaagg ggatatcgaa attcactata gtggattgcg tccgggtgaa aaactttacg
    20701 aagaattatt aattgatcaa gaaaatactg aatataccga gcacagtaga attcttcgat
    20761 catttgaaaa attctatcct cttacagaaa ttcaagaagt ttttgatcga ataaataata
    20821 tgactgctgt tcagcaagat attgattggg ctctttgtca actcgaacac tatgttgatg
    20881 gttataaacg tagtaaagat attatggtta attagagggt aaatgtgtga tcaaaaaagc
    20941 agttttacct gtagccggtt taggcacacg ttttttacca gcaagtaagt caattcctaa
    21001 ggaaatggtc acagtggttg accgtcctgc aattgaatat gtagtacgcg aagctgtaga
    21061 ggctggaatt gagcaaatta ttttagtcac tcattcatct aaagcctcaa tcgaaaatta
    21121 ttttgatcgt aactttgagt tggaaacgac tctagaacaa aagaaaaaat ttgacttact
    21181 tgcagaaatt actcaaattg tgcctgaaca tgtaagtgta atcagtgtta ggcagcctca
    21241 acctttaggt ttaggacatg ctgttttatg tgcaaagagt atcgttggcg aagatgattt
    21301 tgcagtgctc ttaccagatg tgctagtgaa agatagctct ggacaaaatg atctatctcg
    21361 tatgatttct cgctacaact caagccaagc tgctcaaatc atggttgagg cagtgccaga
    21421 tcatttagta gatcaatatg ggattgtcga tgtaaagcat agcccaaatg agggcgaaag
    21481 tattgctatg cagggtattg ttgaaaaacc ccctgtaggt gctgcaccat caaacttatc
    21541 tgtggttggc cgctatgtgt tacctgccaa gattatgcaa ttacttgaga acacgccgaa
    21601 aggtgcaggt aatgaaattc agttaactga tgcaattgca atgctgcaag acatagatac
    21661 tgttgaagct tatcgtatgc aaggccaaac gtttgactgt ggtagtaagc ttggttattt
    21721 aaaagctgta ttacattatg gtttagaaca tccaaaatta ggaatggaat ttaaacagct
    21781 gattcaagaa cttaaattat aaagttttgt agctctgatt aagtatttgt aaaaacgaat
    21841 gaatatatga gcagagcaat atattctctt cctgtaaaag gaagagaaat ctataaaata
    21901 ctaaagaatc aggtgtgcaa tgaaaatcgc agtatttgga acgacgttac atgccggtgt
    21961 aatggccgca ttattggctg aatatggtaa ccaaatttat tggtgtacct gtgtaagttg
    22021 tgaagaaaat atttctgtac tttcgtatca agaccaagaa gtaaatcatt atttaaacaa
    22081 acagcgaaaa gcaggttttt taaaagaaag ccctttttct gaaattcctt tagatatcga
    22141 agtttattta ttttgtttta gtcctacaca aattgaactt gccttaaaaa ctgttgaaaa
    22201 actaagtgaa cggccaatta ttcatcctaa attaatgatt aatggctcta cttttggttt
    22261 acatggtaca gagaaattaa aacagcactt gccgaaagat gaatgggtgt atttccctga
    22321 tgtgattcaa gaaggtaatg caattaatag tgtactagat gtaaaacatg tcattgtagg
    22381 tgtagagtct agggacgcaa gtgaaattat gcaggaattg ttgcgtcctt ttttccaatt
    22441 tagttatcaa tacttattta tgccgatttt agatgctgag tttaccaaac ttagtatttc
    22501 gggcatgtta gctactcgta ttagctatat gaatgatctt gcgatggtcg ctgaaaaact
    22561 cggtattgat attgcaaatg taaagcatgg tatcgctgct gatacacgta ttggtgccgc
    22621 atatttatca ccaggtgtgg gatttggcgg tgagaatttt tcgcatgata ttttgacact
    22681 ttcaagcaca gtgttagaaa cgggaacaaa aagtcgactt ttggagcaag tctgggctat
    22741 taatgagcaa cagaaagaaa ttttgttccg gaagttatgg aattattatc actgtgactt
    22801 gagtggtaaa actgttgcga tttggggagc ctcttttaaa gaaaatactt caaatataca
    22861 taactcaccc attcatattt tattggctgc gttatgggcg caaggggtaa aagtacgttt
    22921 acatgaccct caggctctag atgaaattgc ctcaatatat ggctctcggg aagatcttat
    22981 tttatgtagt gatcaatacg aggctgcaca aaatgctcat gccttgtgtt tagtaacggc
    23041 atggaaacaa tattggagtc ctgactttaa gcgactacaa cagttaatga agcatccttt
    23101 aattttagat gggcgtaata tttatgaccc agcatatgta aaggctagag gttttgctta
    23161 cgaaggagtt ggacgcttat gagtaaatca attgaacaat tcccaaagga tttaagctca
    23221 cctttaatac agcttaagtc ttcagttgag aaaaactcaa aactacatat aaaagagctt
    23281 tttgctttag agccagaacg ttttcaaaat tattctgtaa aatttgatca gttatttttt
    23341 gattatagta aacaacgtat taccaaaaat attttggaac aacttgttgc tcttgcaaac
    23401 aataaacaat taacgcagtg gattaatcgt cttttttcgc aagataaaat taattgtact
    23461 gagcagcgtg ccgctatgca ctgggcctta cgtttaccac cggaatattc taaatttcct
    23521 gaactcacaa aacaggttca tactcaatta cagcgtatgt acgctttggt tgaaaaaatc
    23581 catgctgggc aataccgcgg tgctacgggt gaagtgattc aggatgtcgt taatattggt
    23641 gtaggtggtt ccgatttagg gcctcaaatg gtgacccatg cactatgcga ttttaaagta
    23701 aaaactgcca aacctcttaa tgtacacttt gtttcgacta tggatggtag ccagttatca
    23761 gacttgcttc atcaactgcg tccggaaacg accttattta ttatttcttc aaagtcattt
    23821 ggtactattg ataccttatc aaatgcacaa acagttcgtc agtggcttga aaaagcttta
    23881 ggaaagcatg accgggttgt aaaaagtcac ttcattggtg tatctacaaa agctgaaaaa
    23941 atgactgagt ggggaattgc tcctgaaaat cagttgctgc tttgggattg ggtaggtgga
    24001 cgttattctc tttggtcttg tattggtttc cctatagcgc taacgattgg tatagagggc
    24061 tttcaacagc ttttagctgg tgcacatgct gtcgatgaac actttcaaaa tacaagcttt
    24121 gagcaaaata taccggttct catggcatta ctcggtatct ggaataataa ttttttaaat
    24181 attcagaccc atgcggtatt accttatgac ggaagattaa agtattttgc ttcctatttg
    24241 cagcagcttg aaatggagtc taatggtaag tcgatacaac gagatggtca aaaagttgaa
    24301 ttagatactt gcccgattgt atggggtgag gttggcccaa atgcacaaca tgcattttac
    24361 cagttactcc accaaggaac acaggcagta agctgtgatt ttattgcacc gatccaacgt
    24421 tataatgcag atcactttac ctatgtagag aatgctgagg cattgattga acaacatcac
    24481 ctcgcattat caaattgttt ggcacaatca cgtttactag ctttcggtaa tgaagcacta
    24541 gatgtgaaag aattagaaaa attgcctatt tataaacaat atgaaggtaa tcaaccaagt
    24601 tctacattat tattggatga actaaacccg tataatttag gaatgctgat tgctttatat
    24661 gaacataaag tatttgttca gtctgtgatt tggaacatta acccatttga tcagtggggg
    24721 gtggaaaaag gtaaacagat tgctgatcag ttacttccga ttttaaatgg cattcaaaat
    24781 gatttttcca aacttgatgc ctcgacacgg gggttaatta aaatattgtt aggaaaagta
    24841 gatggctaaa attctagtca ctggtggtgc gggttatatt ggttcacaca cttgtgtaga
    24901 gcttttagaa gctggtcatg aagtttttgt atttgataat ctttcaaata gctcaaaaga
    24961 atctttaaat agagttcaag agatcactca aaaaagttta acttttatag agggtgatat
    25021 tcggaattct gacgagcttg atcgagtgtt tcaagaatat acaattgacg cggttattca
    25081 ttttgcaggt ttaaaagcag tgggtgaaag ccaggaaaaa cctcttattt attttgataa
    25141 taatatttta gggagtattc aactggttaa gtcaatggaa aaagccagtg ttaagacact
    25201 agtatttagc tcttctgctg ccgtatatga tgaagcaaat atctctccgc taaatgaaga
    25261 aatgccaacg ggtatgccaa gtaataacta tggatataca aaactaattg ttgagcaatt
    25321 attacaaaaa ctttcagtag ctgactctaa atggtctatt gctttactac gttattttaa
    25381 cccagtaggt gcgcataaga gtgggcgtat tggtgaagac ccgcaaggta ttccaaataa
    25441 tttaatgcct tatgtgactc aagttgctgt ggggcgccgt gagaaactat ctatttatgg
    25501 taatgattac gatacagtag atggtacagg tgtgcgagat tatatccatg ttgttgactt
    25561 ggcgaatgca catttatgcg ctttaaataa ccgtttacag gcacaaggtt gccgtgcatg
    25621 gaatattggt acaggtaatg gttcttcagt actgcaagtt aaagacacct ttgaaaaagt
    25681 taatggaata cctatagctt ttgaatttgt accacgccga gcaggcgatg tagcaacatc
    25741 ttttgcagac aattgtcgtg cagttgctga gttgggttgg aagcctcaat acggtttaga
    25801 ggatatgctt gctgatagct ggaattggca gaagcaaaat cctaatggct ataactaagt
    25861 aaataaaaaa ggagcaaatc gctccttttt catttttaat tagttctgga ttaatctggt
    25921 taactcatct acataatatt gcattggctg agcttgacgg tctgcacggc tttcaatgtt
    25981 gaggcgtagc aaaggttcag tgtttgaagc acggacgtta aagcgccatg tgccaaagtc
    26041 gaggcttacc ccatcggtac ggtcaatttg tggattttga tcggcataga agtcgaaaat
    26101 cttttgaatc gtagtttgcg tatcggctac tttaaagttg atttcaccac tacaagggaa
    26161 cttggcaatc atattttcaa cgagtgttga gagagattgt cctgtttcag agagtagagc
    26221 aatggtgagt aaccaaggaa tcattccact gtcacagtaa gcaaaatcac ggaaatagtg
    26281 gtgggcactc atttcaccac catatacggc attgtgttca cgcataacat ctttaataaa
    26341 tgcatgcccc gattttgact gtacagcaac acctttatat tcgtcgacga tatcaaacgt
    26401 attccatact aaacgtgggt catgaacaat tttctcacca gactgtttga ttaagaaagc
    26461 ctgagccaat agaccaacaa tatagtagcc ttcaatgaat tgtccttttt catcgaacaa
    26521 gaaacagcgg tcaaagtcgc cgtcccatgc aatacccata tctgctttat gctcaagaac
    26581 agcatttcgg gtactgtcac ggttttcaat taaaattggg ttagggatgc catttgggaa
    26641 agtaccatct gcttcatgat gaattttaat aaattcaact ggtacattaa gcgctttaaa
    26701 tttttcttca atggcatcaa tcacatgacc agctgcacca ttacccgcgt ttaccactaa
    26761 ctttaatgga cggatttttg caggttcaat ataagtcagt agatggtcaa cgaactcagg
    26821 caaaatgtta tagctttggg ttgtagcttt ttggctaact tcttcaaagt tattggtctc
    26881 tgctaaagcc tgaatttctt ttaaaccagt atcggcacta attggacgag cattttctcg
    26941 aaccaatttc ataccgttat agtccattgg gttatgactc gcagttactt ctataccacc
    27001 ttgtacgtct aaatgaaaag cggcaaagta cacttcttca gtacccgtca tgcctaaatc
    27061 aagcacattc acacccgcat catttaaacc gcggatggtc gcttgtttta aagcctcact
    27121 gcttagacga atatcacaac ctacaaccac agtttttggt ttatagattt gtccgtaagc
    27181 gcggccaatt ttataagcga tttcttcatt caattcggtg ccgagtttgc ctcggatatc
    27241 ataagcttta aaacacgtta aagtagtcat tattcagttc aatacaaatg atttaagttt
    27301 taggaattat tataccttta tcagtaaatg gttatgttta ttgttttata tttaaatttt
    27361 gcacttcatt tctgtaggtc atatttaagt ttataagaaa gctttttttg cgactttagt
    27421 cgaataaata aatttataaa ttagaaatag cttgattttt cttagttata ttggtcatac
    27481 caactgtgat aattatttaa tcattgatct taccaataac tgtgtttatg atgcgcattg
    27541 tggtttaagg aaaaacattt gcacttaaat tttaattggt cataccaatt tgtgttaaat
    27601 gttgaaattt taaggtacaa aaattcgccc cggcatttca aggagatgac aatgctcaat
    27661 atgtggcaac aactttatga ccctttaaat aatatttggc tgtctagtgc ggttgcatta
    27721 atcccgatta ttttcttctt tttggccttg gctgtttttc gtttaaaagg cagtattgcg
    27781 ggtacgggca cagttattat tgcattactg attgcactct ttttctatca aatgccgggg
    27841 caaatggcct ttgcatcaat catttacggt ttcttctacg gtctatggcc aatttcatgg
    27901 atcattattg gggcagtttt tctatacaag atttcggtaa aaacaggcca gtttgaagtt
    27961 atccgctcaa gcattctatc tattaccgaa gaccaacgtc tgcaaatgtt actcgttggt
    28021 tttgcatttg gtactttcct tgaaggagct gcgggctttg gtgctcctgt cgcaattacc
    28081 gctgcactac ttgtcggttt agggtttaag ccactttacg ctgctggttt atgtttaatt
    28141 gtaaatacag caccagttgc attcggtgca atgggtattc caattattgt ggcggggcag
    28201 gtttccggtg tagacactat ggaaattagc cagatggtgg gtcgtcagtt gccattttta
    28261 accattattg tgctgttctg gattatggcg attatggatg gctggcgtgg tgttaaggaa
    28321 acttggcctg cggtattggt cggtggtggt gcttttgcga ttgctcagta tctcacctct
    28381 aactttattg gccctgagtt accagacatt accgcagcaa ttgcttcatt ggtcagcctg
    28441 acgttgttat tccgtgtttg gaaaccaaaa catattttcc gttttgaacc tgaagcaggt
    28501 cagactttga ctcagcaacc tacaacagtt caacgttata gtattgggaa aattgcaaag
    28561 gcatggtctc catttgctat tttaacggta atggtcacga tctggagcgt taagccattt
    28621 aaagcattat ttgcaaaaga tggtgctctt gaacactgga tttttaaact tgaagtgccg
    28681 tatttacaca aattggtcga gaaaatgccg ccgattgtgt ccgagataaa accatacgaa
    28741 gcgatttata agtttgactg gttctctgca acaggtactg caatttttat tgctgcgatc
    28801 atcacagtta ttttcttaaa aatgaaagca agtgaggcag taacaacctt cggtgaaacg
    28861 ctcaatgagt taaaaacacc gatttactcg attggtatgg tgttggcatt tgcttttatt
    28921 gcgaactatt caggtttatc tgcaactttg gctttggctc tatcgcatac gggtcatgcg
    28981 tttactttct tctcgccatt tttgggttgg cttggtgtgt tccttactgg ttcagacact
    29041 tcttcaaatg ctttgttctc ggcactacag gcaactacag ctcagcaaat tggtattccg
    29101 gaagtgttat tggtcgctgc gaataccagc ggtggtgtga caggtaaaat gatttctcct
    29161 cagtcgattg ccattgcttg tgcagcggta gggttagttg gaaaagaatc tgacttgttc
    29221 cgtttcacgg taaaacatag catcatattc actgtctttg ttggcatcat tattacggtt
    29281 caggcttatc tggtgccgtg gatgattcca taactccagt gaaggaaacg cgatgagaat
    29341 ctccgatcaa gtggtcatga aattgcaggc attaattgaa gagcgtcaca tgaaaaaagg
    29401 tgatcgtttg cctgccgagc gccagcttgc aactagctta ggagtttctc gtccgtcttt
    29461 gcgtgaagca attcaacagc tcaatagtca aggtgtactg attagtcgcc gtggcgatgg
    29521 aacttatatt cagcaattac ctgaacaatg gccacagcaa ctgattgtga acccgattag
    29581 taacctgatt gaagaagatc cgttataccg ttttgatgtg caagaggcgc gtttggtact
    29641 tgaagggggg actgcatggt atgccgcgtt acgttcgacc ccagaagatc gcgccaaaat
    29701 tcatcattat tttaatgaaa ttagccgcca ccaaaatgca ggtgactcag cacaggcggc
    29761 ggtggccgat gctgaattcc acttagcgat tgctgaagca tctcacaatg tggtgctgat
    29821 tcaaatgatg cgaagtctat ttgatttgct gcaatacaac gtcttgttag ggcgtaaaaa
    29881 agtttataac gaccccgtaa atggtgactt gctcagcgag cagcattttc aggtgatgga
    29941 tgctattgat cgtaaagacc ccgaggccgc acgccaagct gtctgcggtc atattgaatt
    30001 tgtgattaat catgtgcgtt ctctggatga agatgaagct cgccagaaac gtgcaaaccg
    30061 tttaaataga gttgattcaa aatgattatt tcttctggca atgattatcg tgctgcggca
    30121 caacgtcgct tacccccatt tttatttcac tatattgatg gtggagcgta tgcggaatat
    30181 accttaaagc gtaacgtaca agatttgtca gaaattgcat tgcgtcagcg tgtgcttaat
    30241 gacatgtccg cgttgagttt agagacaaaa ctgtttaatg aaacgctgtc gatgccagtt
    30301 gccttggcgc ctgtaggttt aacaggtatg tatgcacgcc gtggtgaagt gcaagccgca
    30361 atggcagccg ataaaaaagg tattccattt acgctttcaa cggtttctgt ttgtccgatt
    30421 gaggaagttg cacctgcaat taaccgtcca atgtggttcc agctttatgt attacgcgat
    30481 cgaggtttta tgcgtaatgc tttggaacgt gcaaaagcag caggttgttc aacactggta
    30541 tttaccgtag atatgcctgt accaggtgca cgttatcgtg atgctcattc gggtatgagt
    30601 gggccaaatg ctgcgatgcg tcgttatatg cagtcagtgt ttcatccgca ttggtcatgg
    30661 aatgtgggtt taatgggtcg tccgcacgac ttgggaaata tctctaaata tttaggtaag
    30721 ccgactgggc ttgaagacta tattggctgg ttaggctcga actttgaccc atcaatttca
    30781 tggaaggacc ttgagtggat tcgtgagttt tgggatggcc caatggtgat taaaggtatt
    30841 ttagatcctg aagatgccaa agatgctgtg cgttttggtg cagatgggat tgtagtgtcg
    30901 aatcacggcg gtcgtcagtt agatggcgtg atgtcatctg ctcgtgcatt gcctgcaatt
    30961 gccgatgcgg tgaaaggtga cttagcgatt ttggctgact caggcattcg taatggttta
    31021 gatgtggtgc gtatgttggc gctcggtgcg gatacggttt tacttggccg tgcgtttgtt
    31081 tatgccttgg cagcagcagg tggacaaggt gtgtcgaact tacttgattt aattgataag
    31141 gaaatgcgtg ttgcgatgac gctcacgggt gctaagtcga tttcggatat taatgcggat
    31201 tgtttagtac aggcgattaa acaaagactt taa
//
