LOCUS       MH449677               21484 bp    DNA     linear   BCT 13-AUG-2018
DEFINITION  Aeromonas hydrophila O16 antigen biosynthesis gene cluster,
            complete sequence.
ACCESSION   MH449677
VERSION     MH449677.1
KEYWORDS    .
SOURCE      Aeromonas hydrophila
  ORGANISM  Aeromonas hydrophila
            Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
            Aeromonadaceae; Aeromonas.
REFERENCE   1  (bases 1 to 21484)
  AUTHORS   Cao,H. and Liu,B.
  TITLE     Genetic diversity of the Aeromonas Hydrophila O antigens and
            development of a suspension array for serotype detection
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 21484)
  AUTHORS   Cao,H. and Liu,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUN-2018) Teda Institute of Biological Sciences and
            Biotechnology, Nankai University, 23 Hongda Street, Tianjin,
            Tianjin 300457, China
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: Velvet Optimiser v. v2.2
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..21484
                     /organism="Aeromonas hydrophila"
                     /mol_type="genomic DNA"
                     /strain="G5181"
                     /host="fish"
                     /db_xref="taxon:644"
                     /country="Japan"
     gene            1..2505
                     /gene="acrB"
     CDS             1..2505
                     /gene="acrB"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux pump subunit AcrB"
                     /protein_id="AXL04907.1"
                     /translation="MARFFIDRPIFAWVIALVIMLAGSLAIIGLPVAQYPSIAPPAVG
                     ISASYPGASAKTVEDSVTQIIEQNMTGLDHLLYMSSQSDSSGRVSVTLTFQPGTDPDI
                     AQVQVQNKLQQAMSLLPQEVQQQGIRVQKTSSSFLMVAAFISKDGAMTNDDLADYVVA
                     NIKEPLSRLDGVGDITLFGSQYSMRVWLDPNKLNRVQMTPGDVQTAIKAQNTQVAFGK
                     LGGTPAVTDQQFTATIMGQTRLSTVAQFNDILLRVNQDGSKVRLKDVARVELAGESYD
                     AEALYNGQPTAAVAIKLATGANALDTAEKVRSKLGELSAYFPANMEIVYPYDTTPFVK
                     ISIEEVVQTLVEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSINT
                     LTMFGLVLAIGLLVDDAIVVVENVERLMSEEDLSPLEATRKSMTQITGALVGIALVLS
                     AVFVPMAFFGGSTGAIYRQFSLTIVSAMVLSVLVALILTPALCATLLKPIKHGEFGAK
                     RGFFGWFNRAFDASANRYQSGVRKVVKQGVRYGIIYAAMLAVLAILFMRMPTSFLPEE
                     DQGVIMSMVQLPVGATKQRTEVVLADMRDYFMKNEKDNVDSVLTVAGFSFAGSGQNSG
                     MAFIKLKDWKERNTPDRSANAIIGRAMGYLFSIKEAQVFAFNLPPIPELGTATGFDFY
                     LQDRAGVGHDKLMAARNQLLGMAAQEPGAGAPERDGRYSPARHQDRLREGAGAGSLHQ
                     RHQQHALQCLGLCLCERLCRQRPGQEGLPAGGCPLPDEPGRSQALVRAQQRGPDGALL
                     RLCQHRLELRLATAGALQRRAGDGDRRGSGTGQEYR"
     misc_feature    1..21484
                     /note="O16 antigen biosynthesis gene cluster"
     gene            2453..3145
                     /gene="orf1"
     CDS             2453..3145
                     /gene="orf1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AXL04908.1"
                     /translation="MPAMEIVGEAAPGKSTGDAMAAIEQMVKQLPEGIGIEWTGLSYQ
                     ERQAGSQAPALYAISLLVVFLCLAALYESWSIPFSVMLVVPLGVLGAIVAATLRGLEN
                     DVYFQVGLLTTIGLSAKNAILIVEFAKELYDRGMGLSEAVVEAARLRLRPILMTSLAF
                     ILGVLPLVISTGAGASSRNAIGTGVMGGMISATVLAIFFVPLFFVLVMRYFTKHSTKQ
                     ARLAHAEEIKHD"
     gene            3138..4547
                     /gene="oprM"
     CDS             3138..4547
                     /gene="oprM"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OprM"
                     /protein_id="AXL04909.1"
                     /translation="MTKTLIALSVTLLLGGCSMAPDYQRPELPQGATWQSNQTGEAAV
                     SSWRKQFLDPALQQLIATALENNRDLRIAALNVEAYEARYRIQRAAQLPTLAANGSGT
                     RQQGSDDLSSTGQGTISSQYGANIGITAYELDLFGRIQSLKDQALETYLAQIETQRST
                     QIALVASVANAYLTLLADQELLALSEATLATEQESYGLTEHKYRLGAASEMELAQGRT
                     ALESAKVSLAQYQRQVKQDRNGLALLLGTSVPALMTEPATLAEVQLAAIPVGAPSSLL
                     QQRPDILAAEHSLKAANANIGAARAAFFPTISLTATAGTASNQLSGLFDGGTGTWTFM
                     PQINLPIFDGGKRIADLDVAEVSTKQAVASYEKSIQTAFKEVADTLGAQTDYQQQLQA
                     QQELVKASQTYFKLAEVRYEKGVDSYLTRLDAQRSLFSAKQGLITTRLAQLSNQVALY
                     KAVGGGWQAADSEGGKGKS"
     gene            5316..6401
                     /gene="rmlB"
     CDS             5316..6401
                     /gene="rmlB"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 46-dehydratase"
                     /protein_id="AXL04910.1"
                     /translation="MKILVTGGAGFIGSAVVRHIIRDTNDSVINLDKLTYAGNLESLA
                     SVANSERYAFEQVDICNRAELDRVFAQHQPDAVMHLAAESHVDRSITGPADFIETNIV
                     GTYMLLEAARAYWNGLDEVRKAAFRFHHISTDEVYGDLPHPDEVAAGTVLPLFTETTP
                     YAPSSPYSASKASSDHLVRAWRRTYGLPTIVTNCSNNYGPFHFPEKLIPLVILNALDG
                     KPLPVYGKGDQIRDWLYVEDHARALYTVVTTGVIGETYNIGGHNEKQNLDVVHTICDL
                     LDEMVPKTGSYRDQITYVADRPGHDRRYAIDASKMSAELAWQPQETFESGIRKTVQWY
                     LDNQQWVNNVKSGSYQSWIEQNYGERA"
     gene            6401..7288
                     /gene="rmlD"
     CDS             6401..7288
                     /gene="rmlD"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="AXL04911.1"
                     /translation="MHILLFGKNGQVGWELQRALAPLGRITAVDFDSTDYCGDFSKPA
                     GVAETVRLVKPDVIVNAAAHTAVDKAESEREFAELLNATSVAAIAKEAEALGAWLVHY
                     STDYVFDGSGERPWLETDATAPLNVYGETKLAGEQGAALCSRHLIFRTSWVYAARGAN
                     FAKTMLRFGKERSEMSVINDQFGAPTGAELLADCTAHAIRVAQCKPEVAGLYHLIASG
                     TTTWFDYAQLVFAKAREAGVELAVTQLNAVPTCAFPTPAKRPHNSRLDTGKFQRTFDL
                     VLPEWTVGVERMLTEILGK"
     gene            7402..8280
                     /gene="rmlA"
     CDS             7402..8280
                     /gene="rmlA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase 1"
                     /protein_id="AXL04912.1"
                     /translation="MTKRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFEQLLGDGSQWGLNLQYKVQPSPDGLAQAFILGEEFIGS
                     DSCALVLGDNIFYGHDLQKQLEAAAAKESGATVFAYHVHDPERYGVVEFDKQGTAISL
                     EEKPLEPKSNYAVTGLYFYDNSVVEIAKSLKPSPRGELEITDVNRIYLEQGNLSVAMM
                     GRGYAWLDTGTHESLIEASNFIQTIETRQGLKVSCPEEIAYRKGFIDTEQVRNLAAPL
                     AKNAYGQYLLKMIKGK"
     gene            8286..8843
                     /gene="rmlC"
     CDS             8286..8843
                     /gene="rmlC"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 35-epimerase"
                     /protein_id="AXL04913.1"
                     /translation="MKCIQTEIPEVLLFEPKVFGDERGFFFESFNHLQFEKAVGYAVT
                     FVQDNHSKSSQGVLRGLHYQASPHAQGKLVRCISGEVYDVAVDIRPDSPYFGRWVGVH
                     LSAENKRQLWIPAGFAHGFVTLSETAEFLYKTTDYYHPESEGAIIWNDSDLNIIWPTS
                     NITLSQKDQVALPLSSYVEAMNLCK"
     gene            8834..9232
                     /gene="fdtA"
     CDS             8834..9232
                     /gene="fdtA"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-D-xylo-hex-3-ulose aminase"
                     /protein_id="AXL04914.1"
                     /translation="MQVKLIPLQTHGDERGSLVALEEGRNIPFEIKRVYYMFKTNQGV
                     RRGFHAHRTLKQVAIAVRGSCRFLLDDGHERVEILLDNPAQGLLIESFMWREMYDFSD
                     DCVLMVLADQLYDENDYVRDYQVFREASKK"
     gene            9229..9978
                     /gene="fdtC"
     CDS             9229..9978
                     /gene="fdtC"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-Fuc3N acetylase"
                     /protein_id="AXL04915.1"
                     /translation="MIHPTSIVSDKAVIGKNVSIGAYTIIYDNVSIEDDTIIEAFCEI
                     GVSNSLSGGERLHIGRKSHIRSHSVFYEGSVFGASLVTGHRVTVREKTIAGKNLQIGT
                     LSDIQGHCQIGDYVRTHSNVHIGQHSKIGNFVWIFPYVVLTNDPHPPSNVMQGVTVSD
                     YAVIATMSVILPGAYIAEGCLIGAHSSLSGITEADTIYAGAPAKAVGATSKLKLKDGS
                     RKPAYPWRAHFTRGYPEDVVQQWVKEFSQDV"
     gene            10384..11487
                     /gene="fdtB"
     CDS             10384..11487
                     /gene="fdtB"
                     /note="FdtB"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-3-amino-36-dideoxy-alpha-D-galactopyranose
                     transaminase"
                     /protein_id="AXL04916.1"
                     /translation="MINFLDLKNVNSRYQQELKDACARVIDSGWYIMGNELSQFEHEF
                     SNYCGVKHVLGVANGLDALILVLDAWKEQGKLKAGDEVIVQANTYIASVLAITQNDLV
                     PVLVEPDPNTYNLCPEIVRAAITKKTKAILPVHLYGQLSPMREIMNIAEEHNLLVLED
                     CAQAHGAMIDGCKAGNWGDAAAFSFYPGKNLGALGDAGAIATNDDSLAEVVCALRNYG
                     SHKKYENLYQGVNSRLDEIQAAMLRVKLAYLESDTTRRQEIAARYCTEITNPAVKLPT
                     FYNPESHVWHLFVIQSATREALQSHLQSCDIQTLIHYPIPPHKQDAYKIFNHMTLPVT
                     ERLHRQVLSLPMDPTMSEEAVTRVIAAVNGFIE"
     gene            11484..12734
                     /gene="wzx"
     CDS             11484..12734
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AXL04917.1"
                     /translation="MRRLLTVTAFTALLTLLRMVAGFIIAKVVAVYTGPTGMAMLGQV
                     QSMVGMLNGLVTAPAGNGVVRFTAEHQANGYEACAPWWKAAIQWIGILLGVVIPLGFL
                     LAKPLSIWLFGNPDYIWLVIISCCALPFSAANTLIASVINGQQQYRRYVIAGMISVCV
                     TTVVMIGLVIKSNLHGALIAAAINSSISGLVMLIISLRQPWFKMRYWWGKTEHIHRKA
                     IGGYVLMAVTSALTAPVALILIRNILVANVGWEVAGYWQAVWKISEAYLAVITMALGT
                     YYLPRLSSLNNVTAIKAEIIGTAKIIMPLVAISAGGVYLCRDIAISLLFTSTFSPARE
                     LFSIQLVGDVIKIASWLVAYPMLSRGAVKWFVSTEIIFSLSFVILSWLFIIHIGVDGV
                     NIAYALNYALYFLFFVVNFDKIAK"
     gene            12744..14168
                     /gene="gt1"
     CDS             12744..14168
                     /gene="gt1"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AXL04918.1"
                     /translation="MSSSCSKIILELKNKITSTDDIEYAISLAEVLAKLLWSNNVGVY
                     SFPDIETYLQVKVIDSIGSSENVRNEDGEILFVISEPYLAGGHTRLMERLSEMLVEDV
                     DLLISKHSGDQEKNRMSSFFASVITVPNSLSILNKIIHISDIYAKYNKLILNIHPDDI
                     ISVLSCGLAKKKNPDLKCFFINHADHVFNVGVTVADIWFEISNFGRKIDKLRGVCCPS
                     SFLGIPLDKNSEFFSENIKYPKSKDDVNKIISAASGAKFKPIKGVSIFPAISELLADY
                     PNAIIYIIGVNFYTDYWWWPVKLKHLSRLKLIKTLPYTEYLSLTKDCDLYIDSHPMPG
                     GTAFVEQCLNGVYCTGIESPLQGYTPLEENKRKAGQSGFSINNLDIIMKRIEAVHSFN
                     KVRERFLNVIHHMTCSGNLLESYKGWTGNEHFLEKKDLKIFPCEMFSLALKDLKLITI
                     MIKTHPYIFVKSVFFFLIRKIIKK"
     gene            14212..15525
                     /gene="wzy"
     CDS             14212..15525
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AXL04919.1"
                     /translation="MEYMVFFIALIFACLSHYKTWPIFGYSAHPIGFVIAFQILVLTL
                     PGVFIISYGENCLGSVTCSLVSESVKNKVFIDYFIVIIALFISISISFLIGGRRYEFT
                     PISNDRGLYLVSGIFLVFIILVAKIFFTKNIPLLTAITGNVVEAEAQKASILRGEDGI
                     SFPIINFFIKYFPLYVYYSCLIAFLNKTCTKNIVLLSFLITSLCILYDLQKGPIVMMV
                     IGSFWLYWARYGKITSIIVGGAFTLIIISFLFYISFDFGGDASYFVDSILNRLFVAQA
                     DGMFWVYNFSKQSDIYLYWGIPFASVLDIQQVDPLSDIIKHVFPDANASWVNATSFLI
                     GEAKAIFGDYSMGVVILTVTANIILLCIISTWLMRVNKAIFYPAIFVMTQTLPLANNI
                     TDLLYGRFLLGFIVFMIFPLFALQFEKCIKFILHPYMTNIKQDNI"
     gene            15522..16361
                     /gene="gt2"
     CDS             15522..16361
                     /gene="gt2"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AXL04920.1"
                     /translation="MIHSRKQILAIVVTYEPDWHLVFENVIKISESIDVFISDNSAEK
                     LLFDDGKIDNIFYWHNGGNIGIAAAQNVAIKFAKTNEYEYVIFIDDDSTISFFKIKEL
                     LADYEYLNGLGYKISALCAMPDQAGGLDLKKTIPGQNRFFFAENLMSSCSVTAVKTFA
                     DVGVFDADLFIDYVDYEWGWRARGMGYSIVIDSSVKFSHHLGEGVLDLKLFKLGIPSP
                     IRHYFQTRNLLRMLTLNYVPIRWKVSQCCLFPLRFIIFSFFYQESKKRRQFFLKGIRD
                     FFK"
     gene            16424..17233
                     /gene="gt3"
     CDS             16424..17233
                     /gene="gt3"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AXL04921.1"
                     /translation="MSFSVLMSLYFKENPYFLDQCLESLFNQTLQANEIILVYDGPIP
                     DELGMVVTRWKSKLPITILPLDKNIGLGQALNKGLEVCNNDIVFRMDTDDICTPNRFE
                     IQISHFKENQDIKLLGAYVAEFDERTEEYHAIKTVPCLYDEIRSYAKYRNPMNHMSVA
                     FRKSAVMAAGGYQDDYLYEDYALWVRMIIKNFLVLNIPEILVYARTGNGMEVRRGGVK
                     YALSEISVQKRFYDIGFISCFEFIRNLLIRLPIRLLPGEFRKKVYRVLLRK"
     gene            17261..18541
                     /gene="wecA"
     CDS             17261..18541
                     /gene="wecA"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AXL04922.1"
                     /translation="MTIISYQRRHSRWYERFFFSSPVLFLMGAFFSVLIPGLERWGWG
                     FWENLDPVRINTLVGAFLAFILTGIILHRILRYPGASPVSYMIPTVTGVYGVLVGILF
                     FIRLEYSRQVLFESYILALLCCWAVYFIGRRYRIPKYALLPFGDYHSLLKNNAAEWRI
                     LEHPDLGSIRYDAVVADLHDNNLAGDWERFLARCALAHIPVYHIKQIGETLTGRVKID
                     HMHENQLGSLLPSPMYTPIKRCLDIIIALIAIPVLSPVMLITAILIKLESPGPVLFLQ
                     NRVGMGNKDFCIYKFRSMCRDSEKNGAQFAQSDDMRVTRVGKVIRKLRIDELPQFFNV
                     LKGDMSLIGPRPEQRTFVDQFDREIPFYMYRHIVRPGISGWAQVVHGYAADADDTRIK
                     IEHDFYYIKHFSLWLDVLIVFKTIRTILTGFGAR"
     gene            18625..19689
                     /gene="wzz"
     CDS             18625..19689
                     /gene="wzz"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="AXL04923.1"
                     /translation="MTSVSHPEREPSNDSVSLDLNAIVFVLWKNKIILILTAVVSCVL
                     GSIYAYTAAQVWTSQALIDQPTSREINHLRLVVNKLVNNNIEPKALASFEKEVIFKDF
                     IKGFNSADNKVNFLIAEGIVDTSPNPQKNDSAQNQKAQLKKLIKTIDARALDKLSDEV
                     TLSFSGDTSGEAKRWLEKYIAFIQAKQVEAKNNELYSIWQNRIKTLDAQYDSVVTDTL
                     QRQKDEIIRTGYSLRISNAAGLDKPVENLNNRDVFYIELGSKALAEKLEVLRSMKDPE
                     IMNPELGSLRLQINSLKSLDIKNVSFQSFSYLSSPDEPISRDKPRRPLIIILSTFLGG
                     ILGAGVVLFRHSFRYRQRGG"
     gene            19766..21484
                     /gene="waaL"
     CDS             19766..21484
                     /gene="waaL"
                     /codon_start=1
                     /transl_table=11
                     /product="ligase"
                     /protein_id="AXL04924.1"
                     /translation="MTKVSFSFWGICFFYLLLGMHFFMHNPGGAGLYLPFNAWGWIFA
                     SLVIGLGLWRVTLQQRLVFSSLQGWLWLGGLLLLLPMAYPGFELKDYAIPRLLGLFAG
                     LLFLFCLYQWQLARASRDRLLYLLLGAVAIEALLGLVQYYLLVPGNWIGYDTHVNRPY
                     GIFQQPNVMASFMATGLALASWLELRGNPHVWLRRLRYGVILAASLLLVVLQSRVGQL
                     GGLLAMLLLVPELRRHRLLARVLALVALGILLGVASQYWIDGLRRGLEAYQSGGMRSI
                     YWPYAAKLIAQSPWVGWGYGSFETTFLHHYMADKALNPAMVQIEYNLDHPHNEFLYWA
                     VEGGIAPMLGMLLMGVTLLWRASRAGWRKGTALLALVTPILLHTQTEYPLYHAIALWW
                     ALLMLVYVLDAEVEEGLLEAGRASWREHVYRPWLLLRFTAIAIPLLVVPFMLTALHTA
                     WVVTKYERGGYKEPTLLLDVINPMAWLTRVEFDVNSVRLTVGLQSNNKAELEAYLEWG
                     QAFVRHTPRANIYANMVIALDALGRKEEARALRSEALALYPADPLLTGTAAKSVATAL
                     ERKPSS"
BASE COUNT     5327 a   4826 c   5513 g   5818 t
ORIGIN
        1 atggcacgat ttttcataga cagacccatt ttcgcctggg tgatcgccct ggtgatcatg
       61 ctggcgggca gcctggccat cataggcctg ccggttgccc agtatccgag cattgcgccg
      121 ccggcggtgg gcatctctgc cagctacccg ggcgcctccg ccaagacggt ggaagactcg
      181 gtgacccaga tcatcgagca gaacatgacc gggctggatc acctgctcta catgtcctcc
      241 cagtcggact cctccggccg ggtgtcggtg accctcacct tccagcccgg gaccgacccc
      301 gacatcgctc aggtgcaggt gcagaacaaa ctgcagcaag ccatgtcgct gttgccgcaa
      361 gaggtgcagc agcaggggat ccgggtccag aagacctcca gcagcttcct gatggtggca
      421 gccttcatct ccaaagatgg cgccatgacc aacgatgacc tggccgacta cgtggtggcc
      481 aacatcaagg agccgctcag tcgtctggac ggggtagggg acatcacctt gttcggcagc
      541 cagtactcca tgcgggtctg gctcgatccc aacaagctca accgggtgca gatgaccccg
      601 ggggatgtgc agaccgccat caaggcgcaa aacacccagg tggcctttgg caagctgggg
      661 ggcaccccgg cggtgaccga tcagcagttc accgccacca tcatggggca gacccgactc
      721 tccaccgtgg cgcagttcaa cgacatcctg ctgcgggtga accaggacgg ctccaaggtg
      781 cggctcaaag acgtggccag ggtcgaactg gccggtgaaa gctacgatgc cgaggcgctc
      841 tacaacgggc aacccaccgc ggcggtggcc atcaagctgg cgaccggtgc caatgcgctg
      901 gataccgccg agaaggtgcg cagcaagctg ggcgagctct ctgcctactt cccggccaac
      961 atggagatcg tctaccccta cgacaccacg ccgttcgtga agatctccat cgaggaggtg
     1021 gtgcagactc tggtggaggc gatcttcctg gtgttctgcg tcatgtatct gttcttgcag
     1081 aacttccgtg ccaccctgat cccgaccatc gccgtgcccg tggtgctgct gggtaccttc
     1141 ggcgtcatgg cggcgttcgg cttctccatc aacaccctga ccatgttcgg tctggtgctg
     1201 gccatcggcc tcctggtgga tgacgccatc gtggtggtgg agaacgtgga gcgcctgatg
     1261 agcgaggagg atctctctcc gctcgaggcg acccgcaagt ccatgaccca gatcaccggc
     1321 gccctggtgg ggatcgccct ggtgctctcg gcggtgttcg tgccgatggc cttcttcggc
     1381 ggctccaccg gtgccatcta tcgccagttc tccctcacca tcgtctcggc catggtgctg
     1441 tcggtgctgg tggcgctgat cctgaccccg gccctgtgcg ccaccctgct caagcccatc
     1501 aaacatggcg agttcggtgc caagcgcggt ttcttcggct ggttcaaccg ggccttcgac
     1561 gccagcgcca accgctacca gagcggggtg cgcaaagtgg tcaagcaagg ggtccgctac
     1621 ggcatcatct atgcggccat gctggcggta ctggccatcc tgttcatgcg catgcccacc
     1681 tccttcctgc cggaagagga tcagggggtc atcatgtcca tggtgcaact gccggtcggt
     1741 gccaccaagc agcgcaccga ggtggtgctg gcggacatgc gcgactattt catgaaaaac
     1801 gagaaggata acgtcgactc cgtgctgacg gtggcgggct tcagcttcgc cggtagcggt
     1861 cagaacagcg gcatggcctt catcaagctg aaagactgga aggagcgcaa cacgccggat
     1921 cgcagcgcca atgccatcat cggccgcgcc atgggctacc tgttcagcat caaggaagcc
     1981 caggtgttcg ccttcaacct gcctccgatc ccggagctcg ggacggccac cggctttgac
     2041 ttctatctgc aggatcgggc cggcgtgggc cacgacaagc tgatggcggc gcgcaaccag
     2101 ctgctcggca tggcggcgca ggaacctggt gcgggtgcgc ccgaacggga tggaagatac
     2161 tccccagctc gacatcaaga tcgactacga gaaggcgctg gcgcagggtc tctccatcag
     2221 cgacatcaac agcacgctct ccagtgcctg gggctctgcc tatgtgaacg actttgtcga
     2281 cagaggccgg gtcaagaagg tctacctgca ggcggatgcc cccttccgga tgaacccgga
     2341 agatctcaag ctctggtacg tgcgcaacag cgcgggccag atggtgccct tctccgcctt
     2401 tgccagcacc gactggagct tcggctcgcc acggctggag cgttacaacg gcgtgccggc
     2461 gatggagatc gtcggggaag cggcaccggg caagagtacc ggtgacgcca tggccgccat
     2521 cgagcagatg gtgaagcagc tgccggaagg catcggcatc gagtggaccg gtctctccta
     2581 tcaggagcgg caggcgggct ctcaggcacc ggccctgtat gccatctcgc tgctggtggt
     2641 gttcctctgt ctggccgccc tctacgagag ctggagcatt ccgttctcgg tgatgctggt
     2701 ggtgccgctc ggggtgctgg gggccattgt ggccgccacc ctgcgcgggc tggagaacga
     2761 tgtctacttc caggtgggcc tgctcaccac catagggctg tcggccaaga acgcgattct
     2821 gatcgtggaa tttgccaaag agctttatga caggggcatg gggctgagcg aagccgtggt
     2881 ggaggcggcg cgcctgcgtc tgcgtccgat cctgatgacc tcgctcgcct tcatcctcgg
     2941 cgtattgccg ctggtgatca gtaccggggc cggcgccagc agccgaaacg ccatcggtac
     3001 cggcgtgatg ggggggatga tcagtgccac cgtgctggcc atcttctttg tgccgctgtt
     3061 cttcgtgctg gtgatgcgct atttcaccaa gcacagcacc aagcaagcgc gtctggctca
     3121 cgccgaggag atcaaacatg actaagaccc tgatcgcctt gagcgtgact ctgctgttgg
     3181 ggggctgttc catggccccc gattaccagc gccccgagct gccacaaggc gccacctggc
     3241 agagcaacca gacgggggag gcggccgtct cctcctggcg caagcagttc ctcgatcccg
     3301 ccctgcagca gttgatcgcc acggccctcg agaacaaccg ggatctgcgt atcgcggccc
     3361 tcaacgtgga ggcctacgag gccagatacc ggatccagcg ggcggcccag ctgccgaccc
     3421 tggcggccaa tggctcgggt acccgccagc agggatcgga cgatctcagc agcacggggc
     3481 agggcaccat cagcagccag tacggcgcca acatcggcat caccgcctac gagctggacc
     3541 tgttcggccg gatccagagc ctcaaagatc aggcgctgga gacctatctg gcgcaaatcg
     3601 agacccagcg cagcacccag atcgccctgg tagcctcggt ggccaacgcc tatctcaccc
     3661 tgctggcgga tcaggagttg ctcgcgctga gcgaggcgac cctggccacc gagcaggaga
     3721 gctatggtct gaccgagcac aagtaccggc tgggggccgc ctccgagatg gagctggccc
     3781 agggccgtac cgcgctggag agcgccaagg tgagcctggc ccagtaccaa cggcaggtga
     3841 agcaggatcg caatggcctg gcgctgctgc tcgggaccag tgttcccgcg ctgatgaccg
     3901 agccggcgac cctggccgag gtgcagctgg cagccatccc ggtgggtgcc ccatccagcc
     3961 tgctgcaaca gcgcccggac atcctggcgg ccgagcacag cctgaaagcg gccaatgcca
     4021 atatcggcgc agcccgtgcg gccttctttc cgaccatctc gctgaccgcg acggcgggca
     4081 ccgccagcaa ccagttgagc gggttgtttg acggtggcac cggtacctgg accttcatgc
     4141 cgcagatcaa cctgccgatc tttgacggcg gcaagcgcat cgcggatctg gatgtggccg
     4201 aggtgagcac caagcaggcg gtggcgagct acgagaagag catccagacc gctttcaagg
     4261 aagtggcgga tacgctcggc gcccagactg actatcagca gcaactgcag gcccagcagg
     4321 agttggtgaa ggcgagtcaa acctacttca agctggcaga ggtacgctac gagaaggggg
     4381 tggacagtta tcttacccgg cttgatgccc agcgttcgct gttcagcgcc aaacaagggc
     4441 tgatcactac ccgtctggcg cagctcagca accaggtcgc gctctacaag gccgtcggcg
     4501 gtggctggca agctgccgat agcgagggtg gcaaaggaaa aagctgacag tagccacact
     4561 ttcctccttg cgttatctta ccgtcacagg gcgaaccatc aggttcgccc tgtttgtttg
     4621 ctgcaaaaac atatacatat gaagctcaag tgacataata cgtcgtgcag atagagttgt
     4681 gatcggtatc agactctggt ggaagagctg aatttttacg tgtgcggcgg ggggcaattg
     4741 taagaaagtg ttacgtgtct ccatccggat tggcaaaaag tggcggtctt gtgagcgcgc
     4801 tccacactga tgcatctttt acttttgagt ccagcgggca atgttctagg ttggcattca
     4861 aaatgctcct ttgttgcatt gaattatcat ttttttgctt gctaaacaga gccacgctgc
     4921 tggatagggg gcaagtcact tactctatga atggttgttt tggctgttca agcggccagg
     4981 aaaggcgtta aaattcgggt tttgcccttg gggcatggca acaattgacg gcggtttttt
     5041 gtaaactggc acgttgaatg tgcaaaagaa atcgcacttt tgtcatcagg gagcggtgac
     5101 agaattttcc caagctggag ggcatatggc caacagcaca cacaatccgg tcaaaagcag
     5161 caatctgggg gctgtaaccc aggggcggta gctattgtct ttttcatggc cggtgccaga
     5221 aattcgctca atttgagcga gcattttcac caccatgaac aatggtaaca ggttcaaaaa
     5281 gaaccaaatt tctattactt ttcaagagca taactatgaa gattcttgtc actggtggcg
     5341 caggctttat cggctcggcg gttgttcgtc atatcatccg ggataccaac gattcagtta
     5401 tcaacctcga taaactcacc tatgcgggca acctggaatc cttggccagt gtcgcaaaca
     5461 gtgaacgtta tgcctttgaa caggtggata tctgcaaccg tgccgaactg gatcgggtgt
     5521 ttgcccagca tcaaccggac gccgtgatgc acctggcggc cgagagccac gtagatcgct
     5581 ccatcacagg cccggccgac ttcatcgaga ccaatatcgt cggcacctac atgctgctgg
     5641 aagcggctcg cgcctactgg aacggcctgg atgaggttcg caaggcggcc ttccgcttcc
     5701 accacatctc caccgacgag gtgtatggtg acctgcccca tccagatgaa gtcgctgctg
     5761 gtacagtgtt gcctctgttc accgaaacca cgccttatgc ccccagcagc ccctattctg
     5821 cctccaaggc ttcaagtgac catctggtgc gtgcctggcg ccgtacttac ggcctgccga
     5881 ccatcgtcac caactgttcc aacaactatg gcccgttcca cttccccgag aagctgatcc
     5941 cgctggtcat cctcaatgcg ctcgatggca agccgctgcc tgtctatggc aagggcgacc
     6001 agatccgtga ctggctctat gtggaagatc acgctcgcgc actctatacc gtggtcacaa
     6061 caggtgtcat cggcgaaacc tacaacatcg gcggtcataa cgagaaacag aatctggacg
     6121 tcgtgcatac catctgcgat ctgctggatg aaatggtgcc caagaccggc tcctaccgcg
     6181 atcaaatcac ctatgtggcc gaccgccctg gccatgaccg ccgttatgcc attgatgcca
     6241 gcaagatgag cgccgaactc gcctggcaac cgcaagagac ctttgaatcc ggtatccgca
     6301 agacagtgca gtggtatctg gataaccagc agtgggtcaa caacgtgaag agcgggtcct
     6361 atcaatcctg gatcgagcag aattacgggg agcgtgcctg atgcatattc tgctgtttgg
     6421 caaaaacggc caggtaggct gggagctgca acgagcactg gctccgctgg ggcggatcac
     6481 tgccgttgat tttgactcca ccgattattg cggcgacttc agcaagccgg ccggcgtagc
     6541 ggagactgtg cgcctggtga agccggatgt catcgtgaac gcagcagccc acacagcggt
     6601 agacaaagcc gagagcgagc gggagtttgc cgagttgctc aacgcgacca gcgtggccgc
     6661 tatcgccaaa gaggcggagg cattgggggc ctggttggtg cactactcca cggattatgt
     6721 gttcgatggc agtggtgagc gcccttggct tgaaaccgat gcgaccgctc cgctcaacgt
     6781 ctacggcgag accaagctgg cgggtgagca aggggccgcg ctttgttccc gtcacctaat
     6841 cttccgcacc agctgggttt acgccgctcg gggggccaac tttgccaaga ccatgttgcg
     6901 ctttggcaag gagcgcagcg agatgtcggt catcaatgac caattcggcg ctccgaccgg
     6961 cgccgagttg ctggccgatt gcaccgccca tgcgatccgc gtggcgcagt gcaaacccga
     7021 ggtcgccggg ctgtaccatc tgattgcctc cggtaccacc acctggtttg actacgccca
     7081 actggtgttt gccaaagcca gagaggctgg cgttgaactg gcggtgacac aactcaatgc
     7141 agtgccgacc tgcgccttcc cgactccggc taaacgcccc cataactccc gccttgatac
     7201 cggcaaattc cagcgcacct tcgatctggt gctgccggag tggaccgtcg gtgtggagcg
     7261 gatgttgacc gagatcctcg gcaagtaaat tactggccag ggatgtagtg actgcctccc
     7321 tggctggcag ggacaaaacg taaaaggcgt ggccgcaagc cacccttttc ttttgcaatt
     7381 taaaaataag aaacaagcat catgaccaaa cgtaaaggca ttattctggc cggtggctca
     7441 ggcacccgtc tctatccggt gaccatggcg gtgagcaagc agctgctgcc tatctatgac
     7501 aagccgatga tctactatcc gctcagcacc ctgatgctgg cggggattcg cgatattttg
     7561 atcatcagca cgccgcaaga tactccccgt tttgagcaat tgctgggtga tggcagccag
     7621 tggggtctga atttgcaata caaggtacaa ccaagcccgg acgggttggc gcaagccttt
     7681 attctgggtg aagagtttat cggctcagac tcctgtgcgc tggtgctggg ggacaacatt
     7741 ttctacggcc acgacctgca gaaacagttg gaggcggcag cggccaaaga gagcggtgcg
     7801 accgtctttg cctaccatgt gcacgacccg gagcgttatg gggtggtgga atttgataag
     7861 caaggtaccg ctatttcact ggaagagaaa ccgttggagc ccaagagcaa ctatgcagtg
     7921 accggcctct atttctacga caacagcgtg gtggaaatcg ccaagagcct gaagccatcg
     7981 ccgcgtggtg agctggaaat taccgatgtg aaccgtatct acctggaaca aggtaacttg
     8041 tcggtggcca tgatgggccg tggttatgcc tggcttgata ccggcactca tgaaagcctg
     8101 attgaggcga gcaattttat tcagacgatt gaaactagac aaggattaaa agtttcctgc
     8161 ccagaggaaa ttgcctatcg gaaaggattc atagacacag aacaggttcg gaatttggct
     8221 gcaccgcttg ccaaaaatgc atatggtcag tacttgctta agatgatcaa agggaaataa
     8281 tctgaatgaa atgtattcaa actgaaattc ctgaggtttt gctctttgaa cctaaggttt
     8341 ttggcgatga gcgtggcttt ttctttgaaa gtttcaacca tctgcagttt gaaaaggctg
     8401 tagggtatgc ggtcacattt gtacaagata atcactccaa atcaagccaa ggtgttttgc
     8461 gtggattgca ttatcaagca tctcctcatg ctcaaggtaa attagtgcgt tgtatttccg
     8521 gtgaagtata tgacgttgca gtagatatcc gtcctgactc cccatatttt gggcgttggg
     8581 ttggtgtgca tttatctgct gaaaataaaa gacaactttg gatacccgct ggatttgctc
     8641 atggttttgt aaccctaagc gaaacagcag aatttttgta taagacaaca gattattatc
     8701 atcctgaaag tgagggtgcc atcatctgga atgactcaga tttaaatatt atatggccaa
     8761 catcaaatat aacactgtcg cagaaagatc aggtagcact gccactatca agctatgttg
     8821 aggctatgaa tttatgcaag tgaaattaat cccgttacaa acacatggtg atgaacgtgg
     8881 ttcactcgtc gcgctggaag aaggaaggaa tatacctttt gaaatcaagc gtgtttatta
     8941 catgttcaag acaaaccaag gggttagacg tggctttcac gcccatcgga cgttgaaaca
     9001 ggttgcaata gcagtccgcg gttcttgtcg ttttttgctt gatgatggtc atgagcgagt
     9061 tgaaatcttg ctggataatc cagctcaggg tctgcttatt gaatcattta tgtggcgtga
     9121 aatgtatgat ttctctgatg actgtgtgtt aatggtcttg gcggaccaac tatatgatga
     9181 gaatgattac gtacgagatt atcaggtgtt tagagaggca tcaaagaaat gattcaccca
     9241 acatctattg tttctgataa agctgtgatc ggtaaaaatg tttcaatagg cgcatacact
     9301 atcatttatg ataatgtttc tattgaggat gacactatta ttgaagcatt ttgtgaaatc
     9361 ggagttagta atagtctctc tggtggtgag cgattacata taggtagaaa atcacacatc
     9421 cgttctcata gtgtattcta tgaagggtct gtttttggtg catcattagt aactggtcat
     9481 agggtgactg ttcgcgagaa aaccattgct ggaaaaaatc tgcaaatagg tactttgtct
     9541 gatattcaag gtcattgtca gatcggtgac tatgttagaa cacacagtaa tgtacatata
     9601 ggtcagcata gtaaaattgg taattttgta tggatatttc catacgttgt actcactaat
     9661 gatcctcatc caccaagtaa tgtaatgcaa ggtgtgacag ttagtgacta tgccgttatt
     9721 gcaacaatgt cagttatctt gcctggtgct tatattgcag aagggtgttt gatcggtgct
     9781 cattcatctc tgtctgggat aacggaagct gatactattt atgcaggagc tccggcaaaa
     9841 gccgttggtg ctacatccaa gctgaagtta aaagatggct ccagaaaacc ggcttaccca
     9901 tggagagcac attttactcg tggttatcct gaggatgtag ttcaacagtg ggtgaaggag
     9961 ttttcacaag atgtataaat tagaagatat taaaataggt atgagtgaat catactctca
    10021 aacgattact gatgccgatg taaaagactt ttcggggata tctggggaca aaaaccctgt
    10081 tcatatggat gaggtatatg caaatgaatc tagatttggc aagcggattg cccatggaat
    10141 gttaagctct agcttcttct ctgcattatt tggtactaaa ttaccaggac agggatgtgt
    10201 atacgttgca caaagcttga aattcagaaa acctgtatat attggcgata ctgttactgc
    10261 tacagtagaa gtcacgtcca ttgatataga taagcgtaga gtattttttg atacctattg
    10321 taaggtaggc aaatcaaaag taatcactgg cattgcagaa atttatattc cagagtgaga
    10381 aaaatgatta acttcctcga tcttaaaaat gtgaattccc gttatcaaca agaattgaag
    10441 gatgcatgcg ctcgtgtcat cgattcaggt tggtatatta tgggtaatga actatctcag
    10501 tttgaacatg agttttcaaa ctactgtggc gtaaagcatg ttttgggcgt tgcgaatggc
    10561 ttggatgcac ttattctggt tttggatgct tggaaagagc agggtaagct gaaagctggt
    10621 gatgaagtca ttgttcaggc aaatacctat attgcgtctg ttcttgctat cactcaaaat
    10681 gatcttgttc cagtattggt tgaacctgat ccaaatactt acaatctatg cccagaaata
    10741 gttcgtgcag ctattacgaa aaaaaccaaa gccattttac cggtacatct ttatggccag
    10801 ctttctccaa tgcgtgagat aatgaatatt gcggaagagc ataatctgct ggtacttgaa
    10861 gattgtgccc aagcccatgg agccatgatt gatgggtgta aggccggcaa ctggggtgat
    10921 gcggcagcat tcagtttcta tccgggtaaa aacttgggtg ccttggggga tgctggcgct
    10981 attgccacca atgatgattc tttagctgaa gttgtatgtg cattgcgcaa ctatggttct
    11041 cataaaaagt atgagaatct atatcaggga gtaaatagtc gtttggatga aattcaggct
    11101 gctatgctca gggtaaagct tgcttatctg gagagtgata ccactcgtcg ccaagaaata
    11161 gcagcacgtt actgtactga aattactaat ccagcagtta aactacctac attttataat
    11221 ccagagagtc atgtatggca tctttttgtc atccaaagtg ctactcgtga ggcactgcaa
    11281 tcacatttgc agtcttgtga tatccaaacc cttatccatt atcctatacc acctcataag
    11341 caagatgcat ataaaatatt taaccacatg acgttaccgg ttacagaacg gttgcatcgg
    11401 caagttttat ctcttcccat ggatcccaca atgtctgaag aggctgtaac tcgagtcatt
    11461 gcggcggtga atggatttat tgaatgagac gcttgttaac agtaacagca tttacagcat
    11521 tattgaccct gctgagaatg gttgctggat ttattattgc caaggtggtg gccgtatata
    11581 ccggccccac cggcatggct atgttgggac aagttcaaag catggtgggc atgttaaatg
    11641 gcctggttac agctcctgcc ggaaatggtg ttgtgcgatt tactgcagaa catcaggcta
    11701 atggttatga ggcatgtgca ccttggtgga aggctgctat tcagtggatt ggtatattat
    11761 taggtgtagt aattccatta ggatttttgt tggctaagcc actatctatt tggcttttcg
    11821 gtaatcctga ttatatttgg ttggttatta tatcttgttg tgcacttccc ttttctgccg
    11881 cgaatacgtt aatcgcatca gttataaatg gtcaacagca gtatcggcgc tacgtcatag
    11941 ctggtatgat ctcggtatgt gtgacaactg ttgtcatgat tggactggta attaagtcaa
    12001 atttacatgg agcgttaata gctgcagcta taaatagcag tatttcaggc ttggttatgc
    12061 taattatatc tctgcggcag ccttggttta aaatgcgtta ttggtggggg aaaactgagc
    12121 atatacaccg taaggcaata ggtggctatg tgctgatggc agtgacttct gctctgactg
    12181 ctcctgtggc gttgatttta attagaaata ttctggtggc caatgttggt tgggaggttg
    12241 ctggttattg gcaggccgtg tggaagatat cggaagcata tttagctgta attacaatgg
    12301 ctcttggcac ttactattta cctcgattgt catcattaaa taacgtgacg gccatcaagg
    12361 ctgaaattat tggtacagct aaaattatta tgccactagt tgctatcagt gctggtggag
    12421 tttatttatg tagagacata gctatatctc ttctatttac atcaactttt tcacctgccc
    12481 gtgagctttt ttctattcaa ctcgttggcg atgtaataaa aatagcgagc tggcttgttg
    12541 cgtatcctat gctatctcgt ggtgcagtga aatggtttgt tagtacagaa ataatatttt
    12601 cactatcatt tgttattcta tcttggttgt ttattatcca cattggagtt gacggcgtaa
    12661 acatcgcata tgccttaaac tatgcattat attttttatt ttttgtcgta aactttgata
    12721 aaatagctaa ataaggcagt tggatgagct cttcatgcag caaaataatt ttagagttga
    12781 aaaataaaat tacttctact gatgatattg aatatgcaat ttccttagcg gaggtgttgg
    12841 ccaagttgct gtggtcaaat aatgttgggg tttatagttt tcctgacata gagacatatc
    12901 tgcaagttaa ggtaatagat tccattggtt cgtcagagaa tgttcgcaat gaagatggcg
    12961 aaattttatt tgttattagt gagccatatc ttgctggcgg acataccaga ctgatggagc
    13021 gactctccga aatgctggtt gaagatgtgg acttgttgat ttctaaacat tctggggatc
    13081 aagaaaaaaa tagaatgtca tctttttttg ccagtgttat tacagtgccc aattcattat
    13141 caattttaaa taaaataatt catatatcgg atatatatgc gaagtataat aagctaattt
    13201 taaatattca tccggatgat ataatatcag tattgtcatg tggattagct aaaaagaaaa
    13261 atccggatct taagtgtttc tttataaatc atgcggacca tgttttcaat gtaggtgtaa
    13321 ctgttgctga tatatggttt gagatcagca attttggccg aaaaatagat aagttgagag
    13381 gggtttgctg tcctagttca ttcttaggta tcccattaga taaaaattct gagtttttta
    13441 gtgaaaatat aaaatatcca aagtcaaaag atgatgtgaa taaaataatt tctgctgctt
    13501 caggggcaaa atttaagccg atcaaagggg tctctatttt ccctgcaata tcggagttgt
    13561 tggctgatta tccaaatgcg atcatctata taatcggtgt gaatttctac actgactact
    13621 ggtggtggcc cgttaagctt aaacatttaa gtcgcttaaa attaataaaa acattgccat
    13681 acactgagta tttatctttg acgaaagatt gtgacttata tatagatagt cacccaatgc
    13741 ctggtggtac tgcatttgtt gagcagtgtt taaatggggt ttattgtact ggtatcgaaa
    13801 gcccgctcca gggttatact cccttagagg aaaacaagcg taaagccggg cagtctgggt
    13861 tcagcattaa taacctggat ataataatga agagaataga agcggttcat tcttttaaca
    13921 aggtgagaga gcgttttctg aatgtgattc atcatatgac atgttctggc aatcttctcg
    13981 aatcatataa ggggtggact ggcaatgaac acttcttaga gaaaaaggat ttaaaaatat
    14041 ttccctgtga aatgttttct ctggctttaa aagacctgaa attaattact attatgatta
    14101 aaacgcatcc gtatattttt gtaaagagtg tatttttttt tcttattaga aaaataatta
    14161 aaaaataata tgtcatgtaa ttattaacgt agagcgagca gagcgatcat catggaatac
    14221 atggtttttt ttatagcgtt aatatttgca tgtttaagcc attataaaac atggcctatt
    14281 tttggatatt cagctcatcc gataggattt gtcatagcat ttcaaatttt agttcttact
    14341 cttcctgggg tatttatcat aagctacggt gaaaattgcc ttgggtctgt cacgtgtagt
    14401 cttgtatccg aaagtgtaaa gaataaagta tttatagatt atttcatagt catcattgct
    14461 ttattcatat ccatatctat ttcttttcta ataggtgggc gtcgctatga gtttacacct
    14521 atttcaaatg accgtggatt atatttagtt tctggtattt ttttggtatt tattattcta
    14581 gttgcaaaga ttttttttac caaaaacata ccgcttctaa cagctatcac aggtaatgtc
    14641 gttgaagctg aagcacaaaa ggcaagtata ttacgtggtg aagatggaat atcatttcca
    14701 ataataaatt tttttattaa gtattttcca ttgtacgtat attatagctg tctgattgca
    14761 tttttgaaca aaacttgtac taaaaacatc gtattattat catttctaat tacctcatta
    14821 tgtatcctat atgatttgca aaaaggtcct attgtgatga tggtaattgg ctcattttgg
    14881 ttatactggg ctcgctatgg aaaaataaca agtattattg ttggcggagc gttcacactt
    14941 attataatca gttttctttt ttacatttca ttcgattttg gtggtgatgc atcatacttt
    15001 gttgattcga tattgaatcg tcttttcgtc gctcaagctg atggtatgtt ctgggtatat
    15061 aatttttcaa aacaaagtga tatttattta tattggggga taccctttgc aagtgtacta
    15121 gatattcaac aagtagaccc attgagtgac atcataaaac atgtattccc tgatgctaat
    15181 gcttcatggg ttaatgcaac atcgttcttg attggagaag ccaaggcaat atttggtgat
    15241 tattctatgg gcgttgttat tttaaccgtg acagctaata taatattgct ctgtattatt
    15301 agtacttggc taatgagggt gaacaaagca attttttatc cagcaatttt tgtaatgacc
    15361 caaacattac ctctggccaa caatattaca gacttgcttt acggaagatt tttattagga
    15421 tttattgtat ttatgatatt tccattgttt gctcttcagt ttgaaaaatg cataaaattt
    15481 attttgcatc cttatatgac caacattaag caggataaca tatgattcat tcaaggaagc
    15541 aaattctggc tattgtcgta acctatgaac cagattggca tctagtgttt gaaaacgtta
    15601 ttaaaatatc ggaaagtata gatgtattca tttctgataa tagtgccgag aagctgttat
    15661 ttgatgatgg gaaaatagat aacatttttt attggcataa tggtggtaat atagggatag
    15721 ctgcagccca gaacgtagcc atcaaattcg ctaaaaccaa tgaatatgag tatgtcatat
    15781 ttatagatga cgatagtaca atttcttttt ttaagataaa agaattgcta gctgattatg
    15841 aatatttgaa tggccttggg tacaagatat cggcattgtg tgcaatgcct gatcaggctg
    15901 gtgggttgga tttaaagaag actattcctg gtcaaaatag atttttcttt gcagaaaacc
    15961 taatgagctc ctgctcagtg acagcggtaa aaacattcgc tgatgtggga gtttttgatg
    16021 cagatctgtt tattgattat gtagactatg aatggggctg gcgtgctcgt gggatgggtt
    16081 attccatcgt cattgactct tcagttaaat tttcccacca tcttggggag ggagtgttag
    16141 acctaaagct attcaagttg gggataccat cgccaatacg acactacttt cagactagaa
    16201 acctattaag aatgctaaca ttgaattatg tgccaattcg atggaaagtc tctcaatgtt
    16261 gcttgtttcc acttagattt ataatttttt ccttttttta tcaagagagc aagaaacgaa
    16321 gacagttctt tctaaaaggc attcgtgatt ttttcaagta ggtgtgcctt aaaatttcag
    16381 cgaaaaaatg ctaaacatta attaattttc attaggctct atcatgtctt ttagtgtttt
    16441 gatgtctcta tactttaaag aaaatccata ttttttggat cagtgtttgg agagtttgtt
    16501 caatcaaact ctccaagcaa atgaaattat tcttgtttat gatggtccga tacctgatga
    16561 gttagggatg gttgttactc gatggaagag taaattacca attactattt taccattaga
    16621 taaaaatatt ggccttggtc aagcactaaa taaaggcctt gaagtatgta ataatgacat
    16681 cgtctttaga atggatacag atgatatctg tactcctaat aggtttgaaa ttcaaatttc
    16741 acattttaaa gaaaaccaag atataaaact gttgggagca tatgttgccg agtttgatga
    16801 acgcactgaa gaataccatg caataaagac tgtaccttgt ctatatgatg agatcagaag
    16861 ttatgcaaag tatcgtaatc caatgaatca tatgtcggtt gcttttagaa aatcggctgt
    16921 catggctgca ggtggttatc aagatgatta tttatatgaa gactatgctc tatgggttag
    16981 aatgataatt aaaaattttc ttgtgttgaa tatccctgag attcttgttt atgcgagaac
    17041 aggaaatgga atggaggtgc gtagaggtgg ggtgaagtat gcactttcag agatatctgt
    17101 gcagaagcgt ttttatgata taggtttcat atcatgtttc gaatttataa gaaatttatt
    17161 aattaggctt ccaattagat tactacctgg cgagttcaga aaaaaagtat atcgtgttct
    17221 attaagaaaa tagttaaatt ttagcgaact ggggactaat gtgactatta taagttatca
    17281 aagacgccac tcccgttggt atgaaagatt ttttttcagc tctcctgtcc tatttttgat
    17341 gggggctttc ttctctgtat tgattcccgg ccttgagcgt tggggctggg gcttttggga
    17401 gaatcttgat cctgtacgaa taaatacact tgttggtgca tttttggctt tcatattgac
    17461 aggaattatt ctgcacagaa tacttcgtta tcctggcgcc agccctgttt catatatgat
    17521 tccaactgtc actggagtct atggcgttct cgtcggcata ctgtttttta ttcgtttgga
    17581 atatagccgg caagttttat ttgaatcata tattttagct ctactgtgct gttgggctgt
    17641 ctattttata ggtcgtagat atagaatacc aaaatatgca ttgttgccat ttggtgatta
    17701 tcattcattg ctaaaaaaca atgctgcaga atggcgaatt ctagagcatc ctgacttggg
    17761 atcaatccgg tatgatgctg ttgtggcaga tcttcatgat aataatttgg ctggtgattg
    17821 ggagcgtttt ctggcgcgtt gcgcactggc gcacattcct gtttatcaca tcaagcagat
    17881 tggtgaaact ctgacgggtc gtgtgaagat agatcatatg catgagaatc aactgggttc
    17941 tctgttacct tctcccatgt atactccaat aaagcgttgc ttggatatta ttattgcact
    18001 tatagcaatc ccagttctct ctcctgtaat gctgataaca gcaattctaa taaaattgga
    18061 aagtcccggg ccagttttat ttttacagaa tcgtgttgga atgggaaata aagacttttg
    18121 tatttataaa ttcagaagca tgtgtcgtga ttcggagaaa aatggtgccc agtttgcaca
    18181 aagtgatgac atgcgcgtca cccgtgtagg gaaagtgatt agaaagttaa gaattgatga
    18241 actaccacag tttttcaacg tattaaaggg tgatatgagt ctaattggtc ccagaccaga
    18301 gcagagaacc tttgtagatc aatttgatcg tgagatacca ttttatatgt atcgacatat
    18361 agtacggcct ggcatcagtg ggtgggctca ggtagtacat gggtatgctg ctgatgcaga
    18421 tgatacaaga attaagattg aacatgactt ttattatatc aaacactttt cattatggtt
    18481 ggatgttctg attgtgttta aaacaatacg aactattttg actggctttg gcgctcgata
    18541 gttattcgct aaggctcatg catgtgtatg aatataatgt cacatgagat aggttcatta
    18601 aaatataata tgagagaata acttatgact tcagtctcac atcctgagcg agagccttcg
    18661 aatgactctg tctcactgga cttgaatgcg attgtctttg tcctgtggaa aaataaaata
    18721 attttgattc tgaccgctgt ggtatcatgt gtattaggaa gtatatacgc atatacagct
    18781 gcacaggtat ggactagtca agccttgatt gatcagccga cctcaagaga gattaatcat
    18841 ctacgacttg tagtaaataa gctggtaaat aataatattg aacctaaagc ccttgcctcc
    18901 tttgaaaagg aagttatatt caaggatttt atcaagggtt ttaatagcgc tgataataaa
    18961 gtgaatttct taattgctga gggtattgtt gatacgtctc caaacccaca aaaaaatgat
    19021 tcagctcaaa atcagaaagc acagttgaaa aagcttatta aaactattga tgccagagcg
    19081 ctggataagc taagtgatga agtcacactc tcgttctctg gtgatacatc aggcgaggcc
    19141 aaacgttggc ttgaaaaata tattgcattt attcaagcca aacaggtgga ggcaaagaac
    19201 aacgagctgt atagcatctg gcagaacaga ataaagacac tggatgctca atatgacagc
    19261 gtggttactg atacattaca gagacagaaa gatgaaatca tcaggactgg atatagcctg
    19321 aggatcagta atgctgcagg cttagataaa cctgttgaga acttgaataa tcgagatgta
    19381 ttttatattg aactaggctc caaggcgttg gcggaaaaac tggaagtgct gcgttcaatg
    19441 aaggatcctg agatcatgaa tccagagttg ggctcgttgc ggttacagat taatagcttg
    19501 aagtctcttg atattaaaaa tgtatcgttt caatcatttt catatctttc atctcctgat
    19561 gagcccattt caagagataa gccacgcagg cctctcatca tcattctatc tacattttta
    19621 ggtggtattt tgggtgcagg ggtggtgttg ttcagacatt cattcagata tcgccagcga
    19681 gggggctgag ataaaggagg catagtcctc ctttattttt atcttgggat gcttactgca
    19741 atcttacata tcaggagcat acgacatgac aaaagtctca ttcagcttct ggggcatttg
    19801 ctttttctac ctgttattgg gcatgcattt tttcatgcac aaccccggtg gggccgggct
    19861 ctatctgccg ttcaacgcct ggggctggat cttcgccagc ctggtcatcg ggttgggact
    19921 gtggcgggtg acgctgcagc agcggctggt gttctcctcg ttgcagggct ggctctggct
    19981 cgggggattg ttgctgctgc tgcccatggc ctatcccggc tttgaactga aagactacgc
    20041 cattccccgt ttgctggggc tgttcgccgg tttgctgttt ctgttctgtc tctatcaatg
    20101 gcaactggcg cgggcatccc gtgaccgact gctctatctg ctgctggggg cggtggccat
    20161 cgaggcgctg ctgggcctgg tgcagtacta cctgctggtg ccgggcaact ggatcggcta
    20221 tgacacccac gtcaaccgcc cctacggtat ctttcaacaa cccaatgtga tggccagttt
    20281 catggcgacc gggcttgcgc tggccagctg gctggagctg cgcggcaatc cccatgtctg
    20341 gctgcgtagg ttgcgctacg gggtgatcct ggctgccagc ctgctgttgg tggtgctgca
    20401 atcccgggtg gggcagttgg ggggcttgct ggcgatgctc ctgctggtgc ccgagctgcg
    20461 tcgtcatcgt ctgctggcca gggtgttggc actggtcgcg ctcggcatct tgctgggggt
    20521 tgcctcccaa tactggattg acggcctcag gcgtgggctg gaggcctatc aatccggcgg
    20581 catgcgctcc atctactggc cctatgccgc caagctgatt gcccagtctc cctgggtggg
    20641 ctggggctac ggcagctttg aaaccacctt cctccatcac tacatggccg acaaggcgct
    20701 gaacccggcc atggtgcaga tcgaatacaa cctcgatcac ccccataacg agttcctcta
    20761 ctgggcggta gaggggggga tagcccccat gctgggcatg ctgctgatgg gcgttaccct
    20821 gctgtggcgg gcgagtcggg ccggctggcg caagggcaca gccctgcttg cgctggtgac
    20881 cccgatcctg ctgcataccc agaccgaata cccgctttac cacgccatcg cgctctggtg
    20941 ggccttgctg atgctggtgt atgtgctgga tgcggaagtg gaggaggggc tactggaggc
    21001 gggacgagcc agctggcgcg agcatgttta ccgcccctgg ctgttattgc gttttaccgc
    21061 cattgccatc cccctgctgg tggtgccctt catgttgacg gcgctgcaca ccgcctgggt
    21121 ggtgaccaag tacgagcgcg gcggctacaa ggagccgacc ctgctgctcg atgtcatcaa
    21181 tcccatggcc tggttgaccc gggtggagtt tgacgtcaat tcggtgcggc tgacggtggg
    21241 cctgcagagc aacaacaagg cggagctgga ggcctatcta gagtgggggc aagccttcgt
    21301 gcgccacacg ccgagggcca atatctacgc caacatggtg atcgcgctgg atgcactggg
    21361 acgcaaggag gaggcgcggg ccctgcgcag cgaagcgctg gcactctatc cggcagatcc
    21421 cttgctgacc ggcacggccg ccaaatccgt ggccacggcg ctggagcgca agccatcctc
    21481 ctga
//
