LOCUS       MH325892               11810 bp    DNA     linear   BCT 20-JUN-2018
DEFINITION  Citrobacter gillenii strain O12_G3535 antigen biosynthesis gene
            cluster, complete sequence.
ACCESSION   MH325892
VERSION     MH325892.1
KEYWORDS    .
SOURCE      Citrobacter gillenii
  ORGANISM  Citrobacter gillenii
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Citrobacter; Citrobacter freundii complex.
REFERENCE   1  (bases 1 to 11810)
  AUTHORS   Qian,C., Liu,B. and Guo,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2018) Teda Institute of Biological Sciences and
            Biotechnology, Nankai University, 23 Hongda street, TEDA, Tianjin,
            Tianjin 300457, China
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: Velvet Optimiser v. Version 2.2
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..11810
                     /organism="Citrobacter gillenii"
                     /mol_type="genomic DNA"
                     /strain="O12_G3535"
                     /db_xref="taxon:67828"
                     /country="Poland"
     misc_feature    1..11810
                     /note="antigen biosynthesis gene cluster"
     gene            1269..2354
                     /gene="rmlB"
     CDS             1269..2354
                     /gene="rmlB"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 46-dehydratase"
                     /protein_id="AWU66631.1"
                     /translation="MKILVTGGAGFIGSAVVRHIIKNTQDTVVNVDKLTYAGNLESLA
                     EVSDSNQYYFEHADICDKAAMERIFATHKPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARGYWNDMDADKKQAFRFHHISTDEVYGDLPHPDEVVAGSMLPLFTEKTA
                     YAPSSPYSASKASSDHLVRAWSRTYGFPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KPLPIYGKGDQIRDWLYVEDHARALYIVVTQGVVEETYNIGGHNEKKNLDVVYTICDL
                     LDEIVPIEGSYRDQITYVADRPGHDRRYAIDAAKISDELGWKPLETFESGIRKTVEWY
                     LSNTQWVENVKSGAYKTWIEQNYGERQ"
     gene            2354..3253
                     /gene="rmlD"
     CDS             2354..3253
                     /gene="rmlD"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="AWU66632.1"
                     /translation="MNILLFGKNGQVGWELQRALAPLGNIIALGVHSTDYCGDFSNPE
                     GVADTVRKICPDVIVNAAAHTAVDKAEAEAEFAQLLNATSVEAIARAAAETGAWVVHY
                     STDYVFPGTGETPWREDDVTAPLNVYGETKLAGEKALQANCARHLIFRTSWVYAGKGN
                     NFAKTMLRFAKERTEMSVINDQYGAPTGAELLADCTAHAIRVALKRPEVAGLYHLVAS
                     GVTTWHDYAALVFEEARKAGIELAINKLTAVPTSAYPTPARRPNNSRLNTEKFQLSFD
                     LVLPEWERGVKRMLAELFTSTTA"
     gene            3308..4186
                     /gene="rmlA"
     CDS             3308..4186
                     /gene="rmlA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="AWU66633.1"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFEQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGN
                     DDCALVLGDNIFYGHDLPKLMDTAVNQGSGATVFAYHVNDPERYGVVEFDKNGTAISL
                     EEKPLEPKSNYAVTGLYFYDNDVVEIAKNLKPSARGELEITDINRLYMEQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDAEQIKRLAIPL
                     SKNAYGQYLIKMIKGY"
     gene            4190..4747
                     /gene="rmlC"
     CDS             4190..4747
                     /gene="rmlC"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="AWU66634.1"
                     /translation="MNVIKTEIPDVLIFEPTVFGDERGFFMESFNQKVFEEAVGRKVD
                     FVQDNHSKSGKGVLRGLHYQLPPFAQGKLVRCIVGEVFDVAVDIRKSSETFGKWVGVK
                     LTAENKKQLWIPEGFAHGFLVLSNVAEFVYKTNNYYMPAYEKGILWNDPQLDIKWSED
                     DKNDDYTLSIKDKSQHFLKNANVFE"
     gene            4807..6144
                     /gene="wzx"
     CDS             4807..6144
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AWU66635.1"
                     /translation="MLRVMFKNIQLIVGLINQSCNIIVPFVITFVSLKILPQEQGSLW
                     LMFLSMVILVSLFDFGLSPTIIRNISYVIAGAQRLSKNDLGNINFGDSISFALLGRLI
                     SDIKSLYKKLTLLAVFFIAFCGGGYFFFVAPNDIFYETMVAWFIFSTGLLLSLYYLYY
                     TPILSGFGEIQYANLANIYGRLSWLVFSLLCIPFGLTLINLSLSFLLSVIVARISCLF
                     FYNRNQFARMVKKTEPEKNSTIPYISGSAIKLGLATAGNVVINRAPIIIAGIAFSLNT
                     AGEFTLTMQIFLAIISVSNVYLAIKIPQLSQLVLKNQRNEIRSLIIKIIIYSAVFYFL
                     GVTMFAFFSDLIIKLTGAKVGFLETKYIILLGFVFLFDLNHNICASILTAGNKIPFVV
                     PVIISGMLIAILGWMLAVPLNMGVIGLIAAQGVVQLSYNNWRWPLMVYQDYIK"
     gene            6262..7368
                     /gene="orf6"
     CDS             6262..7368
                     /gene="orf6"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AWU66636.1"
                     /translation="MIVLLMVISSGARYLGIVSYLALSILIVINVFKNSHKNKRYVII
                     FALLTIFLANSFYTLYLGDNIDPVVGNFLLQILFLLTLDYKKEQPRLVLEAMKWQILL
                     SILLGLVGYIGINNSMLIDAGSAKGFSGFYALAGIFATPQLLASVCIAFLLFQPVFGG
                     NISRNDIYNNICKYTALGVMLLSLNRVNILFYMLWKIVTLLKRKFGGMLILFCMAFFG
                     VILCSITISYLSLDGTLLQTVQSRLALILGVISTIDFNDVWQLLFGVFNSIHFYLPEY
                     FVDINYIENGFLFIFKYFGVLGLITYVAFTSLLAIALFREGYKLLALYAIFYLIVVQN
                     FTNEFVSFIFPQIIYLLMYCAYVKNRDVIVLNKG"
     gene            7373..8491
                     /gene="gt1"
     CDS             7373..8491
                     /gene="gt1"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AWU66637.1"
                     /translation="MKRIAIFHPVDDSYGASKILAYVIGFLSKEYICDVYLPKNNKVI
                     EGMVKGNKNVNFIEVAYLPVIHRGMYNLKGVANWLSMNIKTFNLIRKMRKKYDLIYIN
                     TLALFSISIISKLLNIKNLVHCHEFLQGSVYGRFIKKTVQQCATVIISVSKHVASYIS
                     DDRPNSYVIHNGIPDLCTFETKPINNGFVNFAMVGRIMPEKGQWFLLDALKVMPEKDL
                     AKLKIHVYGDAPPTRKSLMLKFVDDINLAGLHETVIVYGFEPLASEKIQELDCCLVPS
                     LMPDPFPTTVLEAMRASKIVIATNHGGAKEVIENGVNGFSINQSDAKQFSAVLSDIVC
                     MSVSERELMGKNARLTYSMEYTIEQFEKRFINVLSKYL"
     gene            8507..9550
                     /gene="gt2"
     CDS             8507..9550
                     /gene="gt2"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AWU66638.1"
                     /translation="MKKIHIIGTVGVPACYGGFETLVDNLLDDERFDITVYCSSKTYK
                     NKKVEKYKGANLVYVPINANGIQSVAYDVYSMFFAATKKADIILVLGVSGCFFLPVLR
                     KISHAKIVTNIDGLEWRRDKWNSLAKSFLKKSEELAVKFSDVVISDNKAIADYVKNEY
                     AFDSQVIAYGGDHAITKEITFDDKDYAFTVCRIEPENNIAMILGAFSVVNKKLVIVGN
                     WNNSSYGQELRKKYNSCKNIEMLDPIYDTSKLAELRAFCSCYIHGHSAGGTNPSLVEM
                     MHFGKSIICFDCSYNRETTDHKAIYFQDEHSLSEIMKSAKHFGENKDMLEIAREKYTW
                     DKIREQYYNIFEL"
     gene            9583..10254
                     /gene="orf9"
     CDS             9583..10254
                     /gene="orf9"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="AWU66639.1"
                     /translation="MKITRIFSSLSYSDESFNIRVIIRVLCMLLRGSWLSVFTLNRVT
                     FPVFSSKNVRVIGPYNKFIAGKFLKIESNVIIQTESINGIRIGNSCTIGSGTSIRPSG
                     FYGGDRGEGLVIGDRSAIGVNSYIGCSGFIEIGDDVIIGPHFTIISENHNYSDRQIKI
                     KDQGVKRERIKIENNVWIGCNVTVLAGVNIGNGSVIAAGSVVTKSFPPNSLIGGVPAK
                     LIKQI"
BASE COUNT     3448 a   2079 c   2665 g   3618 t
ORIGIN
        1 atggttaatt tgaaagcagt tattccggta gcgggtctgg ggatgcatat gctgcctgcc
       61 acgaaggcaa tccctaaaga gatgctgccg atagtcgaca aaccgatgat tcaatacatt
      121 atcgacgaag ttgtggctgc tgggatcaaa gaaatcgttc tggtgacgca tgcatccaag
      181 aatgccgttg agaaccattt cgacacctct tatgaattag aatcactcct tgagcagcgt
      241 gtgaagcgtc agctgctggc cgaagtgcag tccatctgtc ctccgggcgt gacgatcatg
      301 aacgtgcgtc aggcgcaatt gctgggcctg ggccattcga ttctgtgcgc gcggcccatc
      361 gttggcgaca acccttttgt ggtggtgctg cccgacgttg tgcttgatac ggcaagtgcc
      421 gatccgttac gttataacct ggccgcaatg gtggctcgtt ttaatgaaac cgggcgcagc
      481 caggtactgg ctaaacgtat gcaaggcgat ctttctgaat attcggtcat tcagacgaag
      541 gagcctttaa acaacgaagg taacattagc cgcatcgtcg agttcattga aaaacccgat
      601 cagccgcaaa cgctggattc cgatctgatg gcagtaggtc gctatgtgct gtcggctgat
      661 atttgggcag aactggaaaa aacggaacct ggtgcctggg gacgtatcca actgaccgat
      721 gcaattgctg agctggcgaa aaaacagtct gttgatgcca tgctgatgac cggcgatagt
      781 tacgactgcg gcaaaaaaat gggttatatg caggcatttg tgaagtacgg actgcgcaat
      841 ctgaaggaag gggcgaagtt ccgcaagggc attgagaatc tactgaacga atagatttta
      901 gccttaagtg acgatttgca acaaaaaaat agcggcagtt aacatcccag cgtctatgct
      961 tgatgcacgg gaatgttact gtcgtttttt tgttaaaaac aaagaataac aacaagttaa
     1021 cctactaagt ttaatctgct ttttgttgta tttatccttg tttctggcgg catttggtaa
     1081 gacaattggt ctcagtttta gagagttctg caggagtttg cgggactact cacatcttgg
     1141 catttagtta gtactctggt agctgttaag ccaggggcgg tagcgtgcgt aaatgtctac
     1201 atacttgcat tgtgcatcag cattttaata gtagtcatat acctataaac gagactcgga
     1261 attataacgt gaaaatactt gttactggtg gcgctggttt cattggatct gcagttgttc
     1321 gtcatataat aaaaaatacc caagataccg ttgttaatgt tgataaactt acctacgccg
     1381 gtaatctgga atcccttgct gaagtcagcg atagtaatca atattatttc gagcatgcgg
     1441 atatttgcga taaagcggcg atggaacgta tttttgccac ccataaaccg gatgcggtga
     1501 tgcatctggc tgctgaaagt cacgttgacc gttccattac aggtccagca gcttttatcg
     1561 aaacgaatat tgtcggtact tatgtattgc tagaagctgc ccgtggttat tggaacgata
     1621 tggatgcaga taaaaaacag gcattccgtt tccatcatat ctccactgat gaagtatacg
     1681 gcgacctgcc acatccggat gaagtggttg ctggtagcat gctgcctcta tttaccgaaa
     1741 agacagctta tgcgccgagt agcccatact cagcttcaaa ggcatccagc gatcatctgg
     1801 ttcgtgcgtg gtcgcgtact tatggcttcc caaccattgt gactaattgc tctaacaatt
     1861 atggtcctta tcatttcccg gaaaaactca tcccgctggt gatccttaat gcgcttgaag
     1921 gcaaaccttt acctatctac ggcaagggcg atcagattcg cgactggctc tatgtggagg
     1981 atcatgcccg agccttgtac atcgtggtaa ctcaaggtgt ggtggaagaa acctacaata
     2041 tcggcggtca taacgagaag aaaaacctgg acgtggtata tacgatttgt gacctgctgg
     2101 atgaaatcgt accgatagaa ggctcttacc gtgatcaaat cacttatgtg gcagatagac
     2161 ctggccacga tcgtcgctat gcgattgacg cggcaaaaat cagcgatgaa ctggggtgga
     2221 agccactgga aacgtttgaa agtggcatcc gtaaaacggt ggaatggtac ttgagcaata
     2281 cccaatgggt agagaacgta aaaagtggtg cttacaaaac ctggattgag cagaattacg
     2341 gagagcgtca gtaatgaaca ttctgctttt tgggaaaaat ggtcaggtag gctgggaatt
     2401 gcaacgagct ttagcgcctt tgggaaatat tatcgccctt ggcgttcatt ctacagatta
     2461 ctgcggagat ttcagtaatc ctgaaggtgt tgctgatacc gttagaaaaa tatgcccaga
     2521 tgtcattgtg aatgctgcag cgcatactgc tgtagataaa gcagaagcag aagcggaatt
     2581 tgcgcaattg ctcaatgcga caagcgtaga ggctatcgct agagcggccg ctgaaacggg
     2641 cgcgtgggtg gtacattatt cgacagatta cgttttcccg ggtactggtg aaacaccatg
     2701 gcgagaagat gatgttactg ctccattgaa tgtttatggt gaaacaaaac tggctggtga
     2761 gaaagctctc caggcaaact gtgcccggca cttgattttc cgtaccagtt gggtttacgc
     2821 gggtaaaggt aataactttg ctaaaaccat gctgcgtttt gcaaaagaac gcacagaaat
     2881 gtcagtcatt aacgatcaat atggcgcacc aacgggagca gagctactgg cggactgtac
     2941 agcacatgca attcgtgtcg cactgaaacg accggaagtt gcaggacttt atcacctcgt
     3001 ggcaagtggt gtaaccacct ggcatgacta cgcggcactc gtgttcgaag aagctcgtaa
     3061 agcagggata gagttggcga ttaacaaact gacagctgtg cctaccagtg cataccccac
     3121 acctgctcgc cgtccaaata actctcgcct gaatactgaa aaattccagc tgagttttga
     3181 tcttgtatta cctgagtggg agagaggcgt aaaacgtatg ttggctgaat tatttacgtc
     3241 aaccacagct tgaacccatt attaatgccc gttttacggg cattttgtat ataaaagaga
     3301 tgatgaaatg aaaacgcgta aagggattat tttagctggt ggatcgggta cccgtttata
     3361 tcctgtgacg atggcagtaa gcaaacagct gttacccatt tatgacaagc caatgatcta
     3421 ttatccgctt tctactctga tgctggctgg cattcgggat atcctgatta ttagtacccc
     3481 gcaggatact ccacggtttg aacagctact tggtgacggc agccagtggg gactcaatct
     3541 gcagtataaa gtccaaccaa gccctgatgg cttggctcaa gcttttatca ttggtgaaga
     3601 gtttatcggt aatgatgatt gtgccttagt gttgggtgat aacatctttt atggccacga
     3661 cctgccaaaa ttaatggaca ctgctgtcaa ccagggaagc ggcgcaaccg tatttgctta
     3721 tcatgttaat gaccctgaac gctacggtgt cgttgagttt gacaaaaatg gcaccgccat
     3781 tagtcttgaa gaaaaacctc ttgaaccgaa aagtaattat gcggtaactg gcttgtattt
     3841 ctacgacaac gatgttgttg agatagccaa aaatttgaag ccttccgctc gtggagaact
     3901 cgaaatcacc gacattaacc gcctctatat ggagcagggc cgtttatctg tggcgatgat
     3961 gggtcgcgga tatgcttggt tagatacggg aacacatcag agtttaattg aggctagcaa
     4021 ttttattgcc acaattgaag agcgtcaggg gttaaaggtg tcctgtccgg aagaaatcgc
     4081 gtatcgcaag ggatttatcg atgctgagca gatcaaaaga cttgcaatac cattatcgaa
     4141 aaatgcttat ggccaatatt taattaaaat gatcaagggt tattaagaca tgaatgttat
     4201 caaaactgaa attccagatg tgctaatttt tgaaccaacg gtgtttggtg atgaacgtgg
     4261 ctttttcatg gaaagtttta atcaaaaggt ttttgaagag gctgtaggac gcaaggtcga
     4321 tttcgttcag gataatcatt caaaatcagg taaaggggtt ttacgtggat tgcattacca
     4381 acttcctccc tttgcccaag ggaaattagt gcgttgtatc gttggtgagg tttttgatgt
     4441 tgcagttgat atacgtaaaa gttccgaaac atttgggaaa tgggtggggg tgaagcttac
     4501 cgctgaaaat aagaagcaac tttggatccc tgaaggattt gcgcatggtt ttttggtgct
     4561 aagcaatgtt gctgaattcg tgtataaaac aaataattat tatatgcctg catatgagaa
     4621 aggcatatta tggaacgatc cgcaattaga tataaagtgg agtgaagatg ataaaaatga
     4681 cgattacact ctttctataa aagataaatc acagcatttt ctcaaaaatg cgaatgtttt
     4741 tgaatgaaat ttaggtggtt aattgtaatt ggtcgccccg attcttgaag gatgagaata
     4801 gtaacaatgt taagagttat gtttaagaat attcagctga tagtggggtt aataaaccaa
     4861 tcgtgtaata ttattgtacc atttgttatc acgtttgttt cgttgaaaat tctaccacaa
     4921 gaacagggta gtttatggtt aatgtttttg tctatggtta tccttgttag tcttttcgac
     4981 tttggattat caccgacgat aataagaaat ataagttatg taattgcagg tgctcaacgt
     5041 ttatccaaaa atgatctggg taatataaat ttcggcgact ctatatcatt cgcacttctt
     5101 ggcagattaa tttccgatat aaaatcactc tataaaaaac taaccttact tgcggtattt
     5161 tttattgctt tttgtggcgg cgggtatttc ttttttgttg cgccgaatga tattttttat
     5221 gaaacaatgg tcgcgtggtt tatattcagt actggtttgc ttttgagttt gtattacttg
     5281 tattacaccc cgattttgag tggctttgga gagatacagt atgcaaattt agccaacata
     5341 tatggaagat taagttggct tgtttttagc ttgctgtgta ttccatttgg gttgacgctg
     5401 ataaatctat cgttgtcatt tttgttatct gttattgttg caagaatatc atgtctgttt
     5461 ttctataaca gaaatcaatt tgcaaggatg gttaaaaaaa ccgagcctga gaagaactca
     5521 acaattccat atatctcggg gagtgctatc aaattaggac tagcaaccgc aggtaatgtt
     5581 gttataaatc gtgctccaat aataattgca ggtattgcat tcagtttaaa taccgcaggt
     5641 gagtttacgt taacaatgca gatattttta gcgattatat ctgtgagtaa tgtttattta
     5701 gcaattaaaa tcccacaact ctcacagttg gtcttaaaaa atcaaagaaa tgaaattagg
     5761 tctctaatca taaaaataat catatactct gctgtgtttt attttcttgg cgttactatg
     5821 ttcgcatttt tttcagattt aataataaag ctaactgggg cgaaagttgg ttttttagag
     5881 acgaaataca ttattctttt agggttcgtt ttcctctttg atttgaatca taatatttgc
     5941 gcatctatac ttacagcagg taataaaatc cctttcgtgg tacctgttat tatatcggga
     6001 atgctaattg caattctggg ttggatgctg gcggtaccac tcaacatggg ggtcattggg
     6061 cttattgctg cccagggagt tgtccagttg agttataata attggagatg gccacttatg
     6121 gtttatcaag actatataaa ataatgatgt ttagaaaagc aagtgttgtt gaatttattg
     6181 ctgtttcaca aggagtagtg atgctctcta taggaaaaat aagtcttgat ttgcttagtg
     6241 ggttaaaaaa tgtccaacat tatgatcgta ctcttaatgg ttatttcatc tggtgctcgt
     6301 tatttgggta ttgtttctta tttagccttg agtattttaa tagtaattaa tgtttttaaa
     6361 aatagtcata aaaataaacg atatgttata atatttgccc tcctgacaat ttttttggca
     6421 aattcattct atacgcttta cttaggtgat aatattgatc cggtagtggg taattttctg
     6481 cttcaaattc tttttttatt aacgctggat tataaaaaag aacaacctcg gttggtgctt
     6541 gaagccatga aatggcaaat tttgctatca attttacttg gtcttgttgg gtatataggg
     6601 attaacaatt caatgttaat cgacgcaggc tctgcaaaag ggttttctgg gttctatgca
     6661 ttggcaggta ttttcgccac accacaatta ctagccagtg tatgtattgc gttcctttta
     6721 tttcaaccag tatttggtgg caatatttca cgcaacgata tttacaataa tatttgtaaa
     6781 tatactgccc ttggtgtcat gctgttaagt cttaatagag tgaatatact tttttatatg
     6841 ttatggaaga tagtcactct gcttaaaaga aaatttggcg gcatgttaat attgttttgt
     6901 atggcatttt ttggcgtgat tctttgttca attacgatat cttatttatc attagatggt
     6961 actcttttgc agacagtgca aagtcgattg gcattaatct taggggtgat ctcaacaatt
     7021 gattttaatg atgtctggca acttttattt ggagttttta atagcataca tttttattta
     7081 ccagaatatt ttgtagatat taattatatt gagaatggct tcctttttat ctttaaatat
     7141 ttcggggtat taggtttaat tacgtatgtc gcctttactt ctctactagc catagcctta
     7201 tttagggaag ggtataaatt gttagctctt tacgccatat tctatctaat tgttgttcaa
     7261 aatttcacaa atgaatttgt gtcgtttatt tttccgcaaa taatttactt gttaatgtat
     7321 tgtgcttatg tgaagaatag agacgtaata gtattaaata aagggtaagt acatgaaaag
     7381 aatagctatt tttcatcctg tagatgatag ttatggtgcc agtaaaattt tagcttacgt
     7441 aataggtttt ttgtcaaagg aatatatctg tgacgtatac ctcccaaaga ataataaagt
     7501 tattgaaggg atggttaaag gtaataaaaa tgtgaacttt attgaagttg cttatctacc
     7561 agttatacat cggggaatgt ataaccttaa aggtgttgct aattggcttt ctatgaatat
     7621 caaaaccttt aatttaataa ggaaaatgag aaaaaaatat gatctcatat atataaatac
     7681 gttagctttg tttagcattt ctataatatc aaagttattg aatatcaaaa accttgtaca
     7741 ttgccatgaa tttctacaag gaagtgtata tggcaggttc attaaaaaga cagttcagca
     7801 atgtgccacg gtaataatta gtgtatccaa acatgttgca tcatatatat ctgatgatag
     7861 acctaatagc tatgtcattc ataacggcat ccctgatctt tgtacatttg aaacaaaacc
     7921 aataaataat ggttttgtta actttgcaat ggtcggaaga atcatgcctg aaaagggaca
     7981 gtggtttttg ttagatgctc tgaaggttat gcctgaaaag gatttagcaa aattaaaaat
     8041 tcatgtgtat ggcgatgctc caccaaccag aaagtcttta atgttgaaat ttgttgatga
     8101 tataaatttg gctggtttac atgaaactgt tattgtgtat ggttttgaac ctttagcttc
     8161 agaaaaaata caagaacttg attgttgtct tgtaccatca ttaatgcctg atccttttcc
     8221 aacaacagtt ttagaggcta tgagggcatc aaaaattgtt attgcaacaa accatggtgg
     8281 ggctaaagaa gtcattgaaa atggagtcaa tggattttct ataaaccaga gcgatgcaaa
     8341 acaattttct gcagttttaa gtgatattgt ttgtatgtct gtatctgaaa gagagttaat
     8401 gggtaaaaat gccagattaa cttattcaat ggaatataca attgaacagt tcgaaaaacg
     8461 ctttattaat gttttaagca aatatttatg atggtttagg ttaataatga aaaaaattca
     8521 tattattggt accgtaggtg ttcctgcatg ttatggcgga tttgaaacct tagttgataa
     8581 tttattagat gacgaaaggt ttgatattac ggtctattgt agctcgaaaa catataaaaa
     8641 taaaaaagtt gagaaatata agggagcgaa tttagtttat gtgccaataa acgctaatgg
     8701 tatacagagt gttgcctatg atgtttactc aatgtttttt gctgctacaa aaaaggcaga
     8761 tataatatta gtgctaggtg tttctggttg ctttttttta ccggtgctac ggaaaattag
     8821 tcatgcgaaa attgttacaa atattgatgg cttagagtgg cgacgcgata aatggaattc
     8881 actagcgaag tcatttctaa aaaaatcaga agaattggca gtgaaatttt ctgatgttgt
     8941 gatttcagat aacaaagcta ttgctgatta tgtaaaaaat gagtatgcgt ttgatagcca
     9001 agtaattgca tatggtggag atcatgctat tactaaggaa attacattcg atgacaaaga
     9061 ttatgctttt accgtatgca gaatcgagcc agagaataat atagcaatga tattaggcgc
     9121 atttagtgtt gttaacaaga aacttgttat tgttggaaat tggaacaata gtagctatgg
     9181 tcaggagtta agaaaaaaat ataattcgtg taaaaatata gaaatgcttg atcctattta
     9241 tgatacgtca aaattggctg aactacgcgc gttttgctca tgctatatac atggacactc
     9301 tgcaggtggt acaaatccat cgttagtaga gatgatgcat tttgggaaat ccataatatg
     9361 ttttgattgt agttacaatc gagaaactac tgaccataag gccatctatt ttcaggatga
     9421 gcattctcta tccgagataa tgaagtctgc taagcatttt ggtgaaaaca aagatatgtt
     9481 ggaaatcgcc agggaaaaat acacttggga taaaattaga gaacagtatt acaatatttt
     9541 tgaattatag atggtacttt gcgataacta catagaggca atatgaaaat aactagaata
     9601 ttttcttcgt tatcttacag cgatgaatca tttaatatca gggtaataat ccgtgttttg
     9661 tgtatgttat taagaggcag ttggctttcg gtatttacat taaatagagt tacatttcct
     9721 gtattttcat ctaaaaatgt gcgggttatc ggtccttata acaaattcat tgcaggcaag
     9781 tttctcaaaa ttgagtcaaa tgtgattata caaactgaat caataaatgg aataagaatt
     9841 ggaaattcat gtacaattgg ttcagggaca agtattagac catctggttt ttatggtggc
     9901 gatagagggg aaggattggt aataggcgac cgctcagcta ttggtgtaaa ctcttatatt
     9961 ggatgttctg gtttcatcga aattggtgat gacgtaatca ttggtcctca ttttacaatt
    10021 atatcagaaa atcacaatta ctctgatcgt caaataaaaa taaaggatca aggtgtcaaa
    10081 agagaaagga ttaaaataga aaacaatgtt tggattgggt gcaatgttac tgtcctggcc
    10141 ggagttaata ttggtaatgg cagcgttatt gcagctggct cagttgttac taaatcattt
    10201 ccgccaaatt cacttattgg tggtgtgcct gctaaattga taaaacaaat ataaaacaat
    10261 atagtcgtac taaattacag ctaccttcgg tttcactggg ttaaacatag ctatttatat
    10321 ttgaataaag ctaagatact ataaaaacgt attgaaccat cgcgcatatg tcgcgcggtg
    10381 accacaccag acaggagtat gtaatgtcca agcaacagat cggcgtcgtc ggtatggcag
    10441 tgatggggcg caacttggcg ctcaacatcg aaagccgtgg ttataccgtc tctatcttca
    10501 accgctcccg cgaaaaaact gaagaagttg ttgccgagaa cccgggtaag aaactggttc
    10561 cttattacac ggtgaaagag ttcgttgagt ctcttgagac cccacgtcgt atcctgttaa
    10621 tggtgaaagc gggctcaggc accgacgctg ccatcgattc cctgaagccg tacctggata
    10681 aaggcgacat catcattgat ggcggtaata ccttcttcca ggacactatc cgtcgtaatc
    10741 gtgaactgtc tgccgaaggc tttaacttca tcggtaccgg tgtttccggt ggtgaagagg
    10801 gcgcactgaa agggccttct atcatgcctg gcggccagaa agaagcgtac gagttggttg
    10861 cgccgattct gactaagatc gctgctgttg cagaagacgg tgagccgtgc gtaacataca
    10921 tcggtgctga cggtgcgggt cactatgtga agatggttca caacggtatc gagtatggcg
    10981 atatgcagct aattgctgaa gcctactcct tgctgaaagg tggtttgaac ctgtctaacg
    11041 aagagctggc aagcactttc accgaatgga acaacggtga actgagtagc tatctgatcg
    11101 acatcaccaa agacatcttc accaaaaaag atgaagaagg taaatacctg gttgacgtca
    11161 ttctggatga agccgctaac aaaggtaccg gtaagtggac cagccagagt tctctggatc
    11221 tcggagagcc gctgtcgctg atcactgaat ccgtatttgc gcgttatatc tcctctctga
    11281 aagagcagcg tgttgcagct tctaaagtcc tgaccggacc taaagctcag cttgcgggcg
    11341 acaaaaccga atttatcgag aaagtgcgtc gtgcactgta tctgggtaaa attgtgtctt
    11401 acgcccaggg cttctctcag ctgcgtgccg cttctgacga acacaactgg gatctgaact
    11461 acggtgagat tgccaagatc ttccgtgccg gctgcatcat tcgtgcgcag ttcctgcaga
    11521 agatcaccga tgcttacgct aaaaattccg gtatcgctaa cctgctgctt gatccgtact
    11581 tcaagaacat tgctgatgaa tatcagcagg cgctgcgtga tgtggtggcg tatgccgtgc
    11641 agaacggtat tccggttccg accttctccg cggcggttgc ctattacgac agctatcgtg
    11701 cagaagttct gcctgctaac ctgatccagg cgcagcgtga ctacttcggt gcgcacacct
    11761 ataagcgcac agataaagaa ggcgtgttcc atacggaatg gctggattaa
//
