LOCUS       MH325902               23377 bp    DNA     linear   BCT 20-JUN-2018
DEFINITION  Citrobacter werkmanii strain O38_G3538 antigen biosynthesis gene
            cluster, complete sequence.
ACCESSION   MH325902
VERSION     MH325902.1
KEYWORDS    .
SOURCE      Citrobacter werkmanii
  ORGANISM  Citrobacter werkmanii
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Citrobacter; Citrobacter freundii complex.
REFERENCE   1  (bases 1 to 23377)
  AUTHORS   Qian,C., Liu,B. and Guo,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2018) Teda Institute of Biological Sciences and
            Biotechnology, Nankai University, 23 Hongda street, TEDA, Tianjin,
            Tianjin 300457, China
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: Velvet Optimiser v. Version 2.2
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..23377
                     /organism="Citrobacter werkmanii"
                     /mol_type="genomic DNA"
                     /strain="O38_G3538"
                     /db_xref="taxon:67827"
                     /country="Poland"
     misc_feature    1..23377
                     /note="antigen biosynthesis gene cluster"
     gene            1264..2349
                     /gene="rmlB"
     CDS             1264..2349
                     /gene="rmlB"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 46-dehydratase"
                     /protein_id="AWU66728.1"
                     /translation="MKILVTGGAGFIGSAVVRHIIKNTQDTVVNVDKLTYAGNLESLA
                     EVSENSRYYFELADICDKAAMEHIFAAHKPDAVMHLAAESHVDRSITGPADFIETNIV
                     GTYALLEAARGYWNGLDADKKQAFRFHHISTDEVYGDLPHPDEVQAGSTLPLFTENTA
                     YAPSSPYSASKASSDHLVRAWLRTYGFPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KALPIYGRGDQIRDWLYVEDHARALYTVVTRGIVGETYNIGGHNEKKNLDVVHTICDL
                     LDEIVPKEGSYRDQITYVADRPGHDRRYAIDAAKISDELGWKPLETFESGIRKTVEWY
                     LSNTQWVENVKSGAYKTWIEQNYGERN"
     gene            2349..3248
                     /gene="rmlD"
     CDS             2349..3248
                     /gene="rmlD"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="AWU66729.1"
                     /translation="MNILLFGKTGQVGWELQRALAPLGNLIALDVHSTDYCGDFSDPL
                     GVADTVRRIWPDVIVNAAAHTAVDKAESEIEFARLLNATSVEAIAKAAAEIGAWVVHY
                     STDYVFPGTGETPWRETDATAPLNVYGETKLAGEKVLQTHCANHLIFRTSWVYAGKGN
                     NFAKTMLKLAKERAELSVINDQFGAPTGAELLADCTAHAIRVAMNKPEVAGLYHLVAG
                     GTTTWHDYAALVFEEARKAGIKLALTQLNAVPTSAYPTSARRPENSRLNTEKFQNNFD
                     LVLPQWDVGVKRMLTELFTTTAI"
     gene            3299..4177
                     /gene="rmlA"
     CDS             3299..4177
                     /gene="rmlA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="AWU66730.1"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFEQLLGDGSQWGLNIQYKVQPTPDGLAQAFIIGEEFIGN
                     DDCALVLGDNIFYGHDLPKLMDTAVNQESGATVFAYHVNDPERYGVVEFDKSGTAVSL
                     EEKPLEPKSNYAVTGLYFYDNAVVEMAKNLKPSARGELEITDINQIYMEQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDAAQVAKLAEPL
                     SKNDYGKYLKRMIKGF"
     gene            4181..4729
                     /gene="rmlC"
     CDS             4181..4729
                     /gene="rmlC"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="AWU66731.1"
                     /translation="MNVIKTAIPDVLIFEPKVFGDERGFFFESFNHRIFEEAVGRKIS
                     FVQDNHSKSRKGVLRGLHFQKGEHAQGKLVRCTLGEVFDVAVDIRTSSPTFGKWVGVH
                     LSAENKKQLWIPEGFAHGFVTLSETAEFLYKATNYYAPSAEGSILWSDDAIGIEWPIT
                     QQPELSVKDAVAPLLKQASLFE"
     gene            4739..5713
                     /gene="ddhD"
     CDS             4739..5713
                     /gene="ddhD"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-6-deoxy-delta3 4-glucoseen reductase"
                     /protein_id="AWU66732.1"
                     /translation="MSHLIKIFPSDIEFSGAEDSSILDSALAAGIHLEHSCKNGDCGV
                     CESTLLAGEATDPQGRVYGQGDKILTCNCKPKSNLQLQALYYPELQGQVKKIVPCKVN
                     SIELVSADVMKLTLRLPPTAKMDFLPGQFINLQHEGVTRSYSIANSNEADGIELHIRN
                     VANGQMSSLIFSELQVNTLMRIEGPCGTFFIRESDRPIIFIAGGTGFAPVKAMVEHLV
                     KKTSSREIYIYWGMTLAKDFYSALPQELDEKFEQIHFVPVVSGDDPTWGGRKGFVHHA
                     VIEDFDSLEPFDIYACGSPIMIEACKKDFISKKMSVDNFYCDAFTASK"
     gene            5729..6502
                     /gene="ddhA"
     CDS             5729..6502
                     /gene="ddhA"
                     /codon_start=1
                     /transl_table=11
                     /product="D-glucose-1-phosphate cytidylyltransferase"
                     /protein_id="AWU66733.1"
                     /translation="MKAVILAGGLGTRLSEETIVKPKPMVEIGGKPILWHIMKMYSAH
                     GIKDFIICCGYKGYVIKEYFANYFLHMSDVTFHMAENRMEVHHKRVEPWNVTLVDTGD
                     SSMTGGRLKRVAEYVKDDEAFLFTYGDGVADINIRATIDFHKAHGKKATLTATFPPGR
                     FGALDIRGGQVQSFQEKPKGDGAMINGGFFVLNPSVIDLIENDATTWEQEPLMTLAKQ
                     GELMAYEHAGFWQPMDTLRDKTYLEGLWEKGTAPWKTWE"
     gene            6507..7589
                     /gene="ddhB"
     CDS             6507..7589
                     /gene="ddhB"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glucose 4 6-dehydratase"
                     /protein_id="AWU66734.1"
                     /translation="MIDKSFWQGKRVFITGHTGFKGGWLSLWLSEMGATLKGYSLDAP
                     TTPSLFDIANISSLMESEIGDIRDFEKLRGSIASFKPEIIFHMAAQPLVRLSYKEPIE
                     TYSTNVMGTVHLLEAVKQVGGIKAVVNITSDKCYENREWVWGYRENEAMGGYDPYSNS
                     KGCAELVASAFRRSFFNPQNYAHHGVGLASVRAGNVIGGGDWAEDRLIPDILRSFEND
                     QQVVIRNPHSIRPWQHVLEPLSGYIVVAQKLYTDGVKYSEGWNFGPREEDAKTVEFIV
                     DKMVTLWGEGASWLLDGEDHPHEAHYLKLDCSKAHMQLGWHPRWALVETLGRIVKWHK
                     AWINGSDMLEYSKREIHDYMTTTTFS"
     gene            7616..8929
                     /gene="ddhC"
     CDS             7616..8929
                     /gene="ddhC"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-4-keto-6-deoxy-D-glucose 3-dehydrase"
                     /protein_id="AWU66735.1"
                     /translation="MTAKNLREQISKLVAEYADEALSPKPFNAGVSVVPPSGKVIGAK
                     ELQLMVEASLDGWLTTGRFNDAFEKKLGEFIGVPHVLTTTSGSSANLLALTALTSPKL
                     GNRALKPGDEVITVAAGFPTTVNPAIQNGLIPVFVDVDIPTYNVDASLIEAAVSEKSK
                     AIMIAHTLGNTFDLTEVRRIADKYNLWLIEDCCDALGSTYDGQMVGTFGDIGTVSFYP
                     AHHITMGEGGAVFTKSGELKKLIESFRDWGRDCYCAPGCDNTCGKRFGQQLGSLPFGY
                     DHKYTYSHLGYNLKITDMQAACGLAQLERVEEFVQKRKENFVYLKQGLQSCAEFLELP
                     EATAKSDPSWFGFPITLKETSGVERIDLVKFLDEAKIGTRLLFAGNLTRQPYFANVKY
                     RVVGELTNTDRIMNQTFWIGIYPGLTNEHLDYVVNKFEEFFGLNF"
     gene            8952..9827
                     /gene="abe"
     CDS             8952..9827
                     /gene="abe"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-abequose synthase"
                     /protein_id="AWU66736.1"
                     /translation="MNKKILMTGATSFVGTHLLLSLIKEGYSIIALKRPTTEPTIVNA
                     LIKWVNISDIEKKSEFPENIYAIIHIATDYGRDGTSILEQYKCNVLLPTRLLELLPTL
                     KSKFFISTDSFFGKYERQYGYMRSYMASKRHFIELSKIYVEENPDVCFINLRLEHVYG
                     EEDKAGKLIPYIINKMKNNEDIDCTIAKQKRDFIYIDDVVSAYLKILKEGFNPGHYDV
                     EVGTGRSVELKEVFEIIKKELNSISKINYGAITMRNDEIMESHADTSFLNRLGWSADF
                     SLYDGMKKMLRTKGQ"
     gene            9824..11164
                     /gene="wzx"
     CDS             9824..11164
                     /gene="wzx"
                     /note="fdtC"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AWU66737.1"
                     /translation="MNRIIRILGVDKAIRYVIFGKVISVLTGLLLILLISHYLSKDTQ
                     GYYYTFNSVVALQIIFELGLSTVIIQFASHEMSGLKYDFSEKNIIGESLNKKRYLSLF
                     QLAIKWYAAIALLILLVVGPVGYIFFTQENDLGVHWQGAWLLLTIATALNIFLVSVIS
                     VAEGTGLVADVNKMRMYQSLLAGILAVSFLVCGFGLYATSAIALAGTIIFSIFSYKHF
                     KNIFIQSFKRKSECILEGISWRHEIFPMQWRIALSWISGYFIYFAMTPIAFKYFGAAY
                     AGQLGMSLTLCNMVMATGLAWISTKYPRWGVMVSSKQQAELSKSFKNAVMQSTLFVLA
                     GLAGVYISLWLLKLSGSNIVERFLELQDFFFLSVAIIGNHLVACGATYIRAHKTEKMT
                     LASCIMALLTITTMWFIAYSGYSGFYMLMFAVLTWGYFIPQTYMIFRKFKSTYE"
     gene            11157..12119
                     /gene="gt1"
     CDS             11157..12119
                     /gene="gt1"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AWU66738.1"
                     /translation="MSNRPLLTIAIPTYNRSSCLARLLDSIIQQDNYCCDELEVIICD
                     NASVDETATIAKSYSDKIKNCTYHLNQKNLGMDGNFKKCFELSNGKYLWMIGDDDLIV
                     KGGVSKVLSIIKSHPSLDMIHVGSAAKTALRHDIDTRVSFYSNDVDFISDVKIMFTFI
                     SGMICKRTDKLIRDVSIFSPRISGKYLMHLTWQLSLLKHGADFAVIHNNIIVAEADNS
                     GGYHLYKVFSYNLATIFDIFYPRKNSVSKKIRTSACFFLLNFIGDEDKTKNFDTKNYL
                     KDCDSAFIDLAPYKYGLRFFYKYPNMVPLLRKIKLIIKMVLMQK"
     gene            12319..12933
                     /gene="orf12"
     CDS             12319..12933
                     /gene="orf12"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="AWU66739.1"
                     /translation="MFGYSVRLQLFHIISLLSKVRRKLKAKFFTMLTGYDFEMVGRNF
                     KFKVRPYIKKNNGWPKWGSMRIGDNCWIEAVYDYAGEKFEPCLHIGERLCASDNVHIS
                     CVSSLILENDILIGSKVYIGDHSHGSYKTGCSGLAPPANKMLGDIAPIKIGSCCWIGD
                     NAVILAGSEICGGCVIAANAVVKDLKVDKPCLIGGVPAKVLKVF"
     gene            12935..13978
                     /gene="gt2"
     CDS             12935..13978
                     /gene="gt2"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AWU66740.1"
                     /translation="MNVFISICIPSYNRAEFLEPLLDSIYNQDYATNNTDFEVIICED
                     KSPQRDEIKSIIEKYKIKNNKANLNINLNKDNLGYDRNLKNCISSATGKYCMIMGNDD
                     LLADGALSKIVTVLKANPDIVLATRAYGWFKENPNELCDTVRHLTEDTLFQPGIDAIK
                     FFFRRVGVISGFIVNAEKANRLSCDIFDGRLYYQMYLAGMLMAEGQGYYFSDVITLSR
                     DTEAPDFGNAGTEKGIFTPGGYKPEGRIHMVEGLLLIAKHIENTTKINGVYAGIKRDL
                     ANYFYPYIRDQLDLPLTTYLKMINDFRKIGFANEKLFYIHAILGYVLKRKGYDALIKY
                     IRSKNGGTPRLGI"
     gene            14006..15277
                     /gene="wzy"
     CDS             14006..15277
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AWU66741.1"
                     /translation="MNIFYAAILSVNLFSPYISSWMVGVLPFPPGAILRDVLNALFVV
                     LVLMRFFTERKKIHFSLIFTIFAWGALVLWVIALTIFSSDKVQAIMGGRSYILFPAVF
                     IALAILKVCYSESLNVEKVVHYIILLMLTVAVIAIIDVLMKGELIKLLGYDEHYAGDQ
                     LNLINSYDGMIRATGGFSDALNFGYMLALGVLLCMECFSQGYKRAWMLIASLVIFTAI
                     CMTLTRGAILIAVIIYAFYMISNRKMLLSGITLFLIIIPILMVSTNIFDKYIDTLVGR
                     FTDSSQTSRGSTQGRIDMAMNSLSYLSEHPSGIGLGTQGSGNMLSVKDNRLNTDNYFF
                     WMALETGIVGLIINIFYMASQFYASFSLDRRYDTHRSYAHFRVYFLLGITFFISAALS
                     SAPSSSTFSIYYWTILALMPFLNLSNRRCTI"
     gene            15277..16287
                     /gene="gt3"
     CDS             15277..16287
                     /gene="gt3"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AWU66742.1"
                     /translation="MNNKKILMDISWSNMGGIGRFTDEISKLLTGISCAKIYKKCASP
                     FAPLGLAVNILFQGKVDLILLPGYIPPLFCSKKFIVTIHDLNHLDLNDNSSFFKKLFY
                     KFIIKRGCHQAYKIFTVSNFSKERIAKWSGVEPDKIVTVYNGVSDEFNIDVQPMDLGY
                     EYLLCVGNRKTHKNESRILSAFSKAEIDPSIKLVFSGNPSSDLEKLIVQYGISDRVNF
                     LGFVSESNLPSLYKGSLGLVFPSLYEGFGLPVVEAMACGVPVLTSTTSSLPEVAGEAA
                     ILVDPVSVCAISDGITKLVNDTKLREHLVHEGLLRAKKFSWKNVVNEIEMVLTEACNE
                     TK"
     gene            16274..17431
                     /gene="gt4"
     CDS             16274..17431
                     /gene="gt4"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AWU66743.1"
                     /translation="MKLNEAKISLVHEWLLSYAGSEQVSSAILHAFPEAELYSVVDFL
                     TDEQRSNFLGKHATTTFIQNLPKAKKLYQKYLPLMPLAIEQLDLSDANIIISSAHSVA
                     KGVISGPDQLHISYVHSPIRYAWDLQHQYLRESGLNKGIKGWLAKWFLHKIRIWDYRT
                     AHGVDHFIANSQYIARRIKKVYGREASVIYPPVDVENFEVKDKKEEYYFTASRMVPYK
                     RIDLIVEAFSEMPDKKLVVIGDGPEMKKIKSKVKDNIKLLGYQPFSVLKEHMQNAKAF
                     VFAAEEDFGIIPVEAQACGTPVIAFGKGGALETVRPIGTEGPTGIFFKQQTVVSLHAA
                     ICEFEKASSLFTSQACRDNAERFSRSRFNKEFTNFVDEKWNLFKAEQIIKR"
     gene            17470..18867
                     /gene="manC"
     CDS             17470..18867
                     /gene="manC"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="AWU66744.1"
                     /translation="MAGGTGSRLWPLSREHHPKQFLTVEGEFSMLQNTIKRLSPLLVS
                     EPVVICNDSHRFLVAEQLRAIDKLANNIILEPVGRNTAPAIALAAFCALQNTDDEDPL
                     LLILAADHVIRDEKAFIEAINHAESHATLGKLVTFGIVPTHAETGYGYIRRGEAIDAQ
                     AYAVAEFVEKPDYNTACHYIESGKYYWNSGMFLFRASSFLNELKQLSPDIYHACKRAV
                     GRINPDLDFIRIDKESFTLCPSNSIDYAVMEHTQHAVVVPMDAGWSDVGSWSSLWDIS
                     HKDQQRNVLHGDVFAHSSEDNYIYSESAFISTIGVNNLVIIQTADALLVSDKASVQDV
                     KKVVDYLKKNNRNEHKKHLETFRPWGKYTVIDSGDNYLVKRISVKPGEKFVAQMHEHR
                     VEHWIVVSGTALVTKGELTFIVSENESTFIPVNTIHALENPGVIPLELIEIQSGTYLS
                     EDDIIRLEQRSGYSE"
     gene            18875..20314
                     /gene="manB"
     CDS             18875..20314
                     /gene="manB"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="AWU66745.1"
                     /translation="MNSFYNSRDIINNSGIVFGTSGARGLVTNFSPEVCAAFSVSFLT
                     VMQQQFSFDTIALAIDNRPSSYSMAQACAAALQEKGINIVFYGVIPTPALAYQSISDG
                     IPAIMVTGSHIPFDRNGLKFYRPDGEITKDDEISIIHADASFSQTESEELTVSPVAAE
                     NYISRYTSLFPTPFLKNKRIGIYEHSSAGRDLYKPLFNALGATVITLARSDEFVPIDT
                     EAVSEDDRNKAIKWAAEFQLDAIFSTDGDGDRPLISDENGNWLRGDLLGLLCSLELAA
                     DAVAVPVSCNSTISSGNFFKHVERTKIGSPYVIAAFSTLSENYNRIVGFEANGGFLLG
                     SDICVNQQLLKALPTRDAVLPAIMLLFRSKDKGISAVVEKLPVRYTHSNRLQNVSANT
                     SMSMINVGLSDPKAFLEYIGLNDHHILYTDMTDGLRITLNNNNIVHLRPSGNAPELRC
                     YAEADSPDEAYKLVETVLANIKKQVSQNV"
     gene            20392..21822
                     /gene="wbaP"
     CDS             20392..21822
                     /gene="wbaP"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AWU66746.1"
                     /translation="MDNIDNKYNPQLCKILLAISDLVFFNVALWFSLGCVYLIFDEVQ
                     RFVPQEQLDTRVISHFILSIVCVGWFWVRLRHYTYRKPFWYELKEIFRTIVIFAVFDL
                     ALIAFTKWQFSRYVWVFCWSFALILVPLFRVFTKHLLNKLGIWKKTTIIFGSGQNALG
                     AYSALQSEEMMGFEVIAFFDTDSVDCEISSLPVIKDVEEIWNLNRTGDVHYILAYEYT
                     ELDKTQYWLRELSKHHCRSVTVVPSFRGLPLYNTDMSFIFSHEVMLLRIQNNLAKRTS
                     RFLKRTFDIVCSLLILLIASPLMIYLWYKVTRDGGPAIYGHQRVGRNGKLFPCYKFRS
                     MVMNSQEVLKELLDNDPAARAEWDKDFKLKNDPRITAVGRFIRKTSLDELPQLFNVLK
                     GEMSLVGPRPIISDELERYCDDVDYYLMAKPGMTGLWQVSGRNDVDYETRVYFDSWYV
                     KNWTLWNDIAILFKTVKVVLHRDGAY"
BASE COUNT     6795 a   4209 c   5290 g   7083 t
ORIGIN
        1 atgactaatt tgaaagcagt tattccggta gcgggcctcg ggatgcacat gttgcctgcc
       61 acgaaggcaa tccctaaaga gatgctgccg atcgtagaca agccgatgat tcaatacatt
      121 gtcgacgaga ttgtagctgc tggcattaaa gaaatcgttc tggtaacgca tgcgtcaaag
      181 aatgcagtag aaaaccactt cgatacatct tatgaactcg aatcgttgct tgagcagcgc
      241 gtcaagcgcc agttgctggc tgaggttcag tctatctgtc ctcccggcgt gactatcatg
      301 aacgttcgcc aggcgcaatt actcggtctt ggtcattcaa ttctttgtgc tcgcccaatt
      361 atcggggaca acccgttcgt cgttgtatta ccggacgtcg ttctggatac agcaagtgcg
      421 gaccctctgc gctacaatct ggctgccatg gttgctcgtt ttaatgaaac cgggcgcagt
      481 caggtgctgg ctaagcgtat ggatggcgat ctgtccgagt attccgttat tcagaccaaa
      541 gagcctttgg acaacgaagg taaagtcagc cgtatcgttg aattcattga gaaaccagat
      601 cagccgcaaa cgctggattc cgatctgatg gcggtagggc gctatgtgct ttcggctgat
      661 atttgggctg aattagagca tacacaacct ggcgcgtggg gacgtattca gttaacagat
      721 gcgattgcag aactggcgaa aaaacagtct gtcgatgcca tgttaatgac gggcgacagt
      781 tacgactgcg gtaaaaaaat gggttatatg caggcgttcg ttaagtatgg tttgcgtaat
      841 ctgaaggaag gggctaagtt ccgcaagagc atcgaaaagc tacttaacga gtagagtttc
      901 acaggacttt gtgacggtaa gccagaaaaa atagcggcag ctaacacccc aacgcctatg
      961 atttatgcag tggagtgtta ctgtcgtttt tcatattaaa aataaagaat tacaacgagt
     1021 taacctacta attttaatct gttttttgtt ggattttttc ttgtttctgt aagcatttgg
     1081 taagacaatt agcgtttgaa ttttgcctgc tttgcgatag ctggcgggca ggttacatct
     1141 ttatcattca agtagtgctc tggttgctgc aaggccaggg gcggtagcgt gcataatgcc
     1201 cagatgcgca ttatgtgcca gcatgttaat agtattcata taaacgatat tcggaattaa
     1261 aacgtgaaaa tactagttac tggtggggcg ggtttcattg gatctgcagt agttcgtcat
     1321 attattaaaa atactcagga tactgttgtt aatgtcgata aacttaccta cgccggtaac
     1381 cttgagtccc ttgctgaagt cagtgaaaat agtcgatatt attttgaact cgcggatatt
     1441 tgtgataagg cggctatgga acatattttc gccgcgcata aaccagatgc agtaatgcat
     1501 ctggctgctg aaagtcatgt tgatcgctct attactggtc ctgcagactt tattgaaacg
     1561 aatatcgtcg gcacttatgc attactcgaa gccgctcgtg gctactggaa cgggctggat
     1621 gcagataaaa aacaggcatt tcgtttccat catatctcca cggatgaagt atacggcgac
     1681 ctgccacatc ccgacgaggt acaagccggt agcactttgc cgttgtttac ggaaaatacg
     1741 gcctatgcac cgagcagccc gtactcggct tctaaagcct ccagcgatca tctggttcgc
     1801 gcatggttac gcacctatgg ttttccgaca atcgtcacca actgttccaa caactacggc
     1861 ccgtatcact tccctgaaaa gctgattccg ctggtgatcc tgaatgcact tgagggtaaa
     1921 gcattgccaa tttatggcag aggcgatcag attcgcgact ggttgtatgt tgaagatcat
     1981 gcccgagcgt tatacaccgt tgtgaccagg ggcattgtag gtgaaaccta taatatcggg
     2041 ggtcataacg agaagaaaaa cctggacgtg gtacatacta tttgcgatct actggatgag
     2101 attgtgccta aagaaggttc ttaccgcgat caaataacgt atgtggcgga taggcctggg
     2161 cacgatcgcc gctatgcgat tgatgcagcg aaaatcagcg atgaactggg ctggaagccg
     2221 ctggaaacct tcgagagcgg gatccgtaag actgttgagt ggtatctgtc gaatacgcag
     2281 tgggttgaaa atgtgaaaag cggcgcctac aagacgtgga tcgagcagaa ttacggagaa
     2341 cgcaactaat gaatattctg ctgtttggta aaacagggca ggtgggttgg gaactacaac
     2401 gcgcactagc cccgctgggg aacctgattg cgttagatgt acattcaact gactattgcg
     2461 gtgacttcag cgatccgctg ggcgtggcag acaccgtccg tcgtatctgg cctgacgtta
     2521 tcgtcaacgc agctgcccat acggcagtag ataaggccga gtctgaaata gaatttgcgc
     2581 gattgctaaa tgcgaccagc gtggaggcaa ttgccaaagc tgccgcagaa atcggggcat
     2641 gggtagtgca ttactccacg gactacgttt ttcctggtac cggcgaaaca ccatggcgag
     2701 aaacagatgc tacagcgccg cttaatgtct acggtgaaac gaaactggcg ggtgaaaaag
     2761 tactacaaac gcactgtgcc aaccatctga ttttcagaac cagctgggtg tatgccggta
     2821 aaggcaataa ttttgcgaaa acgatgctga aactggcaaa agagcgcgca gagctttcgg
     2881 tgattaacga ccagttcggt gcgccaaccg gggcggaact tcttgctgac tgtacggcac
     2941 atgctatccg cgttgcgatg aacaaacccg aggtggctgg actctaccac ttggttgcag
     3001 gtggtactac gacctggcat gactatgcag cgctggtatt tgaggaagcc cgtaaggcag
     3061 gaattaaact ggcattaacc cagttaaatg cggtgccgac cagtgcttat cctacatccg
     3121 cacgccgtcc agaaaattct cgcctgaaca ctgaaaaatt ccagaataac tttgatctgg
     3181 tattacctca gtgggacgtg ggtgtaaaac gtatgctgac tgaattgttc acgacaacgg
     3241 cgatttgaac ctttttaacg cccgttaacg gacattttgt acacaaagag atgatgaaat
     3301 gaaaacgcgt aaagggatta ttttagctgg tggttcagga actcgtcttt acccagtcac
     3361 tatggctgtt agcaagcaac tgctgccgat ctatgataag ccaatgatct attacccgct
     3421 ttccacgctg atgctggcag gtattcgtga cattttgatt attagtaccc cacaggatac
     3481 cccgcgattt gaacagttac tgggtgacgg cagccagtgg ggactaaata tacagtataa
     3541 agtacaaccg acgccggatg gcctggccca ggcatttatt attggtgaag agtttatcgg
     3601 taatgatgat tgtgctctgg tgcttggcga caacattttt tacggtcatg acctgcctaa
     3661 attaatggat acagctgtta atcaagaaag cggcgcaacc gtatttgcct atcatgttaa
     3721 cgatcctgaa cgttacggtg tagttgagtt cgataaaagt ggtacagcag ttagccttga
     3781 agaaaaacca ctcgagccga aaagtaatta tgcggtgaca gggttatatt tctatgacaa
     3841 cgctgttgtt gaaatggcaa agaacttaaa accttcagca cgtggcgaac tggaaattac
     3901 cgacattaac caaatttata tggaacaggg aaggttatct gttgcaatga tgggacgtgg
     3961 ctatgcgtgg cttgatacag gtacccatca aagcctaatc gaagccagta actttattgc
     4021 cactatcgaa gaacgccagg gtctgaaggt ctcctgtccg gaagaaatcg cttatcgtaa
     4081 aggattcatt gatgctgcac aggttgcaaa acttgcagaa cccttgtcaa agaatgatta
     4141 tggcaaatac cttaaaagaa tgattaaagg tttctaataa atgaatgtta ttaaaacagc
     4201 aattccagac gttttaattt ttgagccgaa agtatttggc gatgaacggg gattcttttt
     4261 cgaaagtttt aaccacagaa tttttgagga agcagttggc cgtaaaatat cttttgtgca
     4321 agataatcac tcgaaatctc gcaaaggagt actgagaggt ctgcattttc aaaaaggaga
     4381 gcatgcacaa ggtaaattag tgcgctgtac tctgggtgaa gtatttgatg tcgcagtcga
     4441 tatccgcacc agttcaccaa cattcggaaa gtgggtcggc gtacatctgt cagcagaaaa
     4501 taaaaagcaa ttgtggattc ctgaaggttt tgcacatggt ttcgtcactc ttagcgaaac
     4561 tgccgagttt ctttataaag caactaatta ttatgcgcca tctgctgaag gcagtatatt
     4621 gtggagtgat gacgcaattg gtatcgaatg gccgataaca cagcagcctg aactttcagt
     4681 aaaagatgcg gttgctccgc tgttaaaaca agcttcctta tttgagtaaa taattactgt
     4741 gtcacatcta atcaaaattt ttccatcaga tatcgaattc tctggagcag aggactcatc
     4801 aatccttgat tcggcactgg ctgcgggtat acatctggaa cacagttgta aaaatgggga
     4861 ttgcggagtt tgtgaatcga cacttctcgc cggagaggca acagatcctc agggtagagt
     4921 atatggtcaa ggtgataaaa tcctgacgtg caattgtaag cccaagagta acctgcaatt
     4981 acaggccttg tactatcctg aattgcaagg acaggtaaaa aagattgtgc cttgcaaagt
     5041 aaatagtatt gagcttgtct ctgcggacgt catgaagtta actcttcgtt taccaccgac
     5101 tgcaaaaatg gactttcttc cgggccaatt tattaacctg cagcatgagg gcgtaacgcg
     5161 tagctattct attgcgaata gcaatgaagc tgatgggatt gagttgcaca tcagaaatgt
     5221 tgccaatggt caaatgagct cattgatttt cagtgaacta caagttaaca ctctgatgcg
     5281 tatcgaaggc ccatgtggaa ctttttttat cagagaaagt gaccgtccta ttatttttat
     5341 cgcggggggg actggatttg ccccggttaa agccatggtt gagcacttgg tgaaaaaaac
     5401 atcatctcgc gagatctata tctattgggg tatgacttta gccaaagatt tttattctgc
     5461 actaccgcaa gaactagatg aaaaatttga acaaattcat tttgttccgg tggtgtctgg
     5521 tgatgatcca acatggggtg ggcgaaaagg ttttgttcac catgcagtaa tagaagattt
     5581 tgattcgctg gagccatttg acatttatgc ttgtggctca ccgatcatga tcgaagcatg
     5641 caaaaaagat tttatttcta aaaaaatgtc agttgataat ttctattgtg atgcttttac
     5701 cgcatctaaa taaaatagag gattaggtat gaaagcggtg attttggctg gtgggcttgg
     5761 taccagatta agtgaagaaa caatagtaaa accaaagcca atggttgaaa ttggtggtaa
     5821 accgatactt tggcatatta tgaaaatgta ctctgcccac ggcattaaag attttattat
     5881 ctgctgtggg tataaagggt atgtaatcaa agaatatttt gcaaactatt tcctgcatat
     5941 gtctgatgta acattccata tggcagagaa tcgaatggaa gttcatcaca agcgtgtaga
     6001 accatggaac gtaactttgg ttgatacagg tgattcttct atgactggcg gacgtttgaa
     6061 gcgcgtagcc gaatatgtaa aagatgatga agccttcctg tttacctatg gcgatggtgt
     6121 tgctgatatt aatatccgag cgacaattga ttttcataaa gcacatggta aaaaagcgac
     6181 cctgacggcg acttttcctc cgggacgttt tggtgcgctg gatatccgtg gtggccaggt
     6241 tcaatcattt caggaaaaac cgaaaggcga tggtgcaatg attaacggtg gcttctttgt
     6301 gctgaatcct tcggtaattg atctcattga aaatgatgcg actacctggg aacaagagcc
     6361 gttgatgaca ttggcgaaac agggtgaact catggcctat gagcatgcag gattctggca
     6421 gccgatggac acgctgcgtg ataaaacgta tcttgaaggt ctatgggaaa aagggactgc
     6481 cccttggaaa acgtgggagt gatatcatga ttgataagag cttctggcag ggcaagcgtg
     6541 tatttattac cggtcatacg gggtttaagg gggggtggct ttctctttgg ctaagtgaaa
     6601 tgggcgcaac gctaaaaggg tattcccttg atgcccccac aaccccaagt ttatttgaca
     6661 ttgccaatat cagttcgctg atggagtcgg aaataggtga tattcgtgat tttgaaaaat
     6721 tacgtggctc aatagcatct tttaagccag aaattatttt ccatatggca gcacaacctc
     6781 ttgtcagact gtcttacaaa gagcctattg aaacttattc aacgaatgtc atgggtacag
     6841 tgcatttact tgaagcggta aaacaagttg gtggcataaa ggctgtagtt aatatcacca
     6901 gcgataaatg ctatgaaaat cgtgaatggg tttggggtta ccgcgaaaac gaagctatgg
     6961 gcggctatga tccatactct aatagcaaag gatgtgctga attagttgct tctgcatttc
     7021 gtcgttcgtt ttttaatcct caaaattatg ctcaccatgg tgttggcctt gcttcagtta
     7081 gagcaggaaa cgttattggt ggtggtgatt gggcggaaga tcgtctgatt cccgatattt
     7141 tgcgttcttt tgagaatgac cagcaggttg ttattcgtaa ccctcactcc atccggccat
     7201 ggcaacacgt acttgaacca ctttcaggat atatcgtggt tgcacaaaaa ctctacactg
     7261 acggtgtgaa atactcagaa ggttggaatt ttggccctcg tgaagaggat gctaaaacgg
     7321 ttgagtttat tgtcgataag atggttacgt tgtggggaga gggggcgagt tggttgttgg
     7381 atggcgagga tcatccacat gaggcacact atctcaaact ggactgctca aaagcgcata
     7441 tgcaattagg ttggcaccct cgatgggcgc tagttgaaac acttggtcgt attgttaaat
     7501 ggcacaaagc atggataaac ggctcggata tgctggaata ttcgaaacgt gaaattcatg
     7561 attacatgac cactactact tttagctaaa atagataagt acaggaatta tagcaatgac
     7621 agcaaaaaac ctgcgtgaac aaatttccaa actcgttgcc gagtatgccg atgaggcgtt
     7681 aagcccaaaa ccttttaatg caggtgtgag tgttgtacca ccttcaggaa aggtcatcgg
     7741 cgccaaagaa ttgcagctga tggttgaagc atctttagat ggatggctta ccacggggcg
     7801 ttttaatgat gctttcgaaa agaaactcgg tgagtttatt ggcgtgcctc acgtattaac
     7861 aaccacttca ggctcgtcag caaacttgtt agcgttaact gcattgacct caccaaaatt
     7921 aggcaaccgt gcactgaagc caggtgatga agttattact gtcgcagcag gatttcccac
     7981 aactgttaac ccagcaatcc agaacggatt gattccagtt tttgttgatg tagatatccc
     8041 aacttataat gttgatgctt ctcttattga agccgctgtt agtgaaaaat caaaagcgat
     8101 tatgatcgcg cacacattgg gtaacacgtt tgatttaact gaagttcgcc gtattgcaga
     8161 taagtataat ctttggttaa tcgaagattg ctgtgatgca cttggctcga cgtatgatgg
     8221 ccagatggta ggtacattcg gtgatattgg gactgtgagt ttctatccgg cccaccatat
     8281 cacgatggga gagggggggg ctgtcttcac taaatcgggt gagttaaaga aattgattga
     8341 gtctttccgc gactgggggc gtgattgtta ctgcgcgcca ggttgtgata atacctgcgg
     8401 gaaacgtttt ggtcagcaac ttggttctct gccgttcgga tacgatcaca aatacaccta
     8461 ttctcatttg ggttataacc tgaagattac ggatatgcag gctgcatgtg gcctggcaca
     8521 gctagagcgc gttgaagagt ttgtgcaaaa gcgcaaagag aactttgtat atcttaagca
     8581 aggtttacaa tcctgtgctg agtttcttga gttgccggaa gccacagcga aatctgaccc
     8641 ctcctggttc ggtttcccta taacacttaa agaaactagc ggtgttgaac gtatcgattt
     8701 agtgaagttt cttgatgaag ccaaaatcgg tacccgtctg ttattcgcag gtaatctgac
     8761 tcgtcaaccg tatttcgcga atgtgaagta tcgagtagtg ggtgaattaa caaatacaga
     8821 ccgcataatg aatcaaacct tctggattgg tatttatcca ggactgacta atgaacactt
     8881 agattatgtg gttaataagt ttgaagaatt ctttggtttg aatttctaat tattaatata
     8941 gggcgcttaa tgtgaataag aaaatcttaa tgacaggtgc tactagcttt gtaggtaccc
     9001 atctgctact gagtctaata aaggaaggtt atagcattat tgcattaaag cgtcctacta
     9061 cggagccaac gattgttaat gccttgatta aatgggtaaa tatatctgat atagaaaaaa
     9121 aaagtgaatt tcctgaaaat atttatgcaa taatacacat tgcaacagat tatggtcggg
     9181 atggaacatc tatattggaa caatataaat gtaatgtact gttgcctaca aggttgcttg
     9241 aactactgcc aacgctaaaa tctaaatttt tcatttccac tgactctttt tttggaaagt
     9301 atgagaggca gtatggatat atgcggtcat atatggcatc taaaagacac tttattgaac
     9361 tttctaaaat atatgtagag gaaaatccgg acgtttgttt tataaaccta cgcttggaac
     9421 atgtatatgg tgaagaggac aaagcaggta agctgattcc ttatattatt aataaaatga
     9481 agaataacga agatattgat tgtacaatcg cgaagcaaaa aagagatttc atttatatag
     9541 atgacgttgt ttcggcatat ttgaaaattc taaaagaagg atttaatccc gggcattatg
     9601 atgttgaagt aggtactgga cgatcggttg aattaaaaga agtgtttgag ataataaaaa
     9661 aagaactaaa tagcattagc aagataaatt atggagcaat tacgatgcgt aatgatgaaa
     9721 ttatggagtc tcacgcagat acttcttttt tgaatcgatt gggatggagt gccgattttt
     9781 ccctttatga tggtatgaaa aaaatgttga gaacgaaagg tcaatgaatc gtattatcag
     9841 aatattgggt gtagataaag caattcgcta tgtcattttt ggtaaagtaa tatctgtttt
     9901 aacaggactg ttgctgatac tgctgatatc gcactattta tctaaagata cacagggcta
     9961 ctattataca tttaattcag tagtggcatt gcaaataatt tttgaattgg gattgtcaac
    10021 ggtaataata caattcgcta gtcatgaaat gtcaggtcta aaatatgatt tttctgaaaa
    10081 aaatattatt ggcgaaagtt taaataaaaa acgctatctc tcactatttc agttggcaat
    10141 aaaatggtat gcagcaatag cattgttaat actattagta gtagggcccg ttggttatat
    10201 attttttacg caagaaaatg acttgggagt gcattggcag ggggcatggc tattattaac
    10261 aatagcaaca gctttgaata tttttcttgt ttcagttatt tctgtcgctg agggtactgg
    10321 tttagttgcc gatgtaaata aaatgagaat gtaccaatct ctgttagctg gtatattggc
    10381 tgtaagcttt ctagtttgtg gttttggact gtatgctact tctgcaatag ctctcgctgg
    10441 tactattata ttctctatct tttcatataa gcattttaaa aatattttca ttcaatcttt
    10501 taagcgtaaa agtgaatgta ttttggaggg gatttcatgg aggcatgaga tatttcctat
    10561 gcaatggcga attgccctga gttggatatc tgggtatttt atctattttg caatgactcc
    10621 aattgcattt aagtattttg gggccgccta tgcagggcaa ctggggatgt ctttaacatt
    10681 atgcaatatg gtgatggcta caggcttggc ttggatatct actaaatatc caagatgggg
    10741 agtaatggtt tccagcaagc agcaggcaga actgagtaaa tcttttaaaa atgcagtaat
    10801 gcaatccacc ctttttgttc ttgctggttt agctggtgtg tacatttctc tatggctatt
    10861 gaaattatct ggttcaaaca ttgtagagag attccttgaa ttacaggatt tcttctttct
    10921 atctgtagca attattggca accaccttgt agcctgcggt gcgacctata taagggccca
    10981 taaaactgaa aaaatgacat tggcgtcatg cattatggca ctactgacta taactacaat
    11041 gtggtttata gcgtattcag gatattctgg gttctacatg ttaatgtttg cagtgttgac
    11101 atggggatat tttattccac aaacttatat gatatttaga aaatttaaga gtacttatga
    11161 gtaatagacc tcttctgact attgcaattc caacatataa ccgttcttca tgcttagctc
    11221 gtttgcttga tagcataatt caacaggata actattgctg tgacgaactt gaagttatca
    11281 tttgtgataa tgcatcagta gatgaaacag caacaatagc caagagttac tcggacaaaa
    11341 taaaaaactg tacttatcat cttaatcaaa aaaacttagg aatggatggt aatttcaaaa
    11401 aatgtttcga gttatcaaat ggaaaatatc tttggatgat tggagacgat gatctaattg
    11461 ttaagggggg ggtttctaaa gttttgtcga taataaagtc tcatccgtcg ttagatatga
    11521 ttcatgtagg ttcagcagca aagacggcat tgagacatga tattgacaca agggtatcat
    11581 tttactcaaa tgatgtggat tttatttcag atgtaaaaat tatgtttact tttatttctg
    11641 ggatgatatg caagagaact gataaactta ttagggatgt tagcattttc agtcctcgaa
    11701 tctctggaaa atatctcatg catttaacat ggcaattatc attacttaaa catggagctg
    11761 attttgctgt tatacacaat aatataattg tggctgaagc ggataattct ggagggtatc
    11821 atctatacaa ggtattttcc tataatcttg cgacgatctt tgatatattt tatcctagaa
    11881 aaaacagtgt aagtaagaaa attcgaacat cggcatgctt ctttctactt aactttatag
    11941 gtgatgaaga taaaactaag aacttcgata caaaaaatta tttaaaagat tgcgatagtg
    12001 catttattga tctggctcct tataaatatg ggctaagatt tttctacaag tatcctaaca
    12061 tggtgccatt acttagaaaa ataaaattga ttataaaaat ggttttaatg caaaaatgaa
    12121 aaatactcct aataatttat tatggtgaat ccaatatctg tgataaatat acaattgtat
    12181 agttttcaaa atgagaggct gtgtggtttg agtcttataa atctcaacca gctacagata
    12241 gataaattga tgtaaagtca atgagtgact cttcaatttc tattaattaa actatgcgac
    12301 tagctatagg actatttaat gtttggctat agtgtaagat tacaattatt tcatattata
    12361 tcgttgttga gcaaagttag gcggaaactt aaagcaaagt tttttactat gcttactgga
    12421 tacgatttcg aaatggttgg aagaaatttt aaatttaaag ttagacctta catcaaaaaa
    12481 aataatgggt ggcccaaatg gggtagtatg cgtattggtg ataactgctg gattgaagct
    12541 gtatatgatt acgctggtga aaaatttgaa ccttgcttac atataggtga gcgtttatgt
    12601 gcaagtgaca acgttcatat ttcttgtgta tcgtctttaa ttttagaaaa tgacatatta
    12661 ataggaagca aagtctacat aggagatcat agccatggta gctataaaac tggctgttcg
    12721 ggactagcac caccagctaa taaaatgtta ggtgatattg ctcctattaa aattgggagc
    12781 tgttgttgga ttggagataa tgcagtaatt ttagctggca gtgaaatttg tggtggttgt
    12841 gtaattgcag ctaatgcagt agtcaaagat ttgaaagttg ataagccatg tttaattggt
    12901 ggagttcctg ccaaagtatt aaaggttttt taaaatgaat gtttttatca gtatttgcat
    12961 accttcctat aaccgtgcag aatttttaga gcccttattg gatagcatat acaatcaaga
    13021 ctatgctact aataatacag acttcgaagt tattatttgt gaagacaaat ctccacaaag
    13081 agatgaaata aagtctatta ttgaaaaata taagataaaa aacaataaag ctaaccttaa
    13141 tattaatctg aacaaagaca atttagggta tgatagaaat ttaaaaaatt gcattagttc
    13201 tgctactggc aaatattgca tgatcatggg caatgatgat ctgttagctg atggagcttt
    13261 atctaagatc gttactgtct tgaaggcaaa tcctgatatt gtattggcaa cgcgggcgta
    13321 tggttggttt aaagaaaatc caaatgaatt atgcgatacc gttcgccatt taactgagga
    13381 tacattattc caaccaggca tagatgctat taaatttttc ttccgtagag ttggtgttat
    13441 ttctggtttt atagtgaatg ccgagaaagc aaatagatta tcctgtgata tttttgatgg
    13501 ccgattatat tatcaaatgt atctggctgg aatgcttatg gctgaaggtc aaggatacta
    13561 ttttagtgat gtaattactt tgtcaagaga tacagaagct cctgattttg gtaatgcagg
    13621 aactgaaaaa ggtattttca ccccaggtgg ttataaacct gaggggcgga tacatatggt
    13681 tgaaggactt ctcctcatag caaaacatat agaaaataca acaaaaatta atggtgtcta
    13741 tgctggtatt aaaagggatt tagcaaacta tttttatcct tacattcgag atcaacttga
    13801 tttaccatta actacatatt taaaaatgat taatgatttc cgaaaaatcg gttttgctaa
    13861 tgaaaagttg ttttatattc atgctatttt gggatatgta ttaaaacgaa aaggttatga
    13921 tgcgttgatt aaatatattc gtagcaaaaa tggcggcact ccgcgtcttg gtatttaaac
    13981 tctctaaatt aaaaatagta gttatatgaa tatattctat gctgcgatat taagtgtcaa
    14041 cttattctct ccatacatta gctcgtggat ggttggtgta ttaccatttc ctcccggagc
    14101 aattcttagg gatgtactga atgcactttt tgtagtgttg gtgctgatgc gttttttcac
    14161 tgagaggaag aaaattcact tttcccttat ttttactatt tttgcatggg gggcactagt
    14221 tttatgggta atagcattaa ctatattttc atctgacaaa gttcaagcca ttatgggagg
    14281 gcgaagttat attttgttcc ctgccgtttt cattgcatta gcaattttaa aagtttgcta
    14341 ttctgaatct ttaaacgttg agaaagtggt tcattatatt attttgttaa tgcttactgt
    14401 agcagtgata gctatcattg atgtattaat gaaaggtgaa cttattaaac tgcttggtta
    14461 tgatgaacac tatgcgggag accagttaaa cttaattaac agctatgatg ggatgattag
    14521 agcaactggt ggtttcagtg atgctcttaa tttcgggtat atgttggcat taggtgttct
    14581 actatgcatg gagtgctttt cgcaaggata taaaagggca tggatgttga ttgctagttt
    14641 ggttattttt actgcaatct gtatgacttt gacccgaggg gcaatcctta ttgcagttat
    14701 catctatgct ttttacatga tttcaaaccg aaaaatgcta ctaagtggta ttacattatt
    14761 tttaataatc attcctatct taatggtatc tacaaatatt tttgataagt atatagatac
    14821 gttagttggc agatttacag actcatcgca gacatcacgt gggtctacgc agggacgaat
    14881 agatatggca atgaattcct taagttatct ttcagagcac ccatctggta taggtttagg
    14941 tacacaaggt tcaggaaaca tgctttccgt taaagataac agattaaata cggataacta
    15001 tttcttctgg atggcactag aaactggaat tgttggctta attattaata ttttttatat
    15061 ggcaagtcag ttttatgctt cattttcttt agacagaaga tatgatactc atcgtagtta
    15121 tgcgcatttt agagtatatt ttctgcttgg gataactttc ttcattagtg cagcattgag
    15181 ttctgcacct tcgtcatcaa ctttttcaat atattattgg acaattttag ctttaatgcc
    15241 ttttttgaac ttgtctaata ggcggtgtac aatttaatga ataataaaaa aatactgatg
    15301 gatattagtt ggtctaacat gggggggatt ggtcgtttca cagacgagat ctcgaagtta
    15361 ttgactggaa tatcatgtgc aaaaatatat aaaaaatgtg cttctccttt tgccccactt
    15421 ggacttgctg taaatatcct ttttcaggga aaagttgatt tgattttact tcctggctat
    15481 ataccaccac ttttttgttc aaaaaaattt atagttacaa tacatgattt aaatcatctt
    15541 gatttgaatg ataactcgtc tttttttaaa aagctatttt ataaattcat aatcaaacgg
    15601 ggctgtcatc aggcttataa aatatttacg gtttcaaatt tttctaaaga aagaatagca
    15661 aagtggtcgg gagttgaacc cgacaaaatt gttaccgttt ataatggtgt atctgacgaa
    15721 tttaatattg atgttcagcc tatggattta ggatatgaat atctgttatg tgtaggaaat
    15781 cggaaaactc ataaaaatga aagccgtatt ttatctgcat tttccaaagc ggagatagac
    15841 ccttcaatca aactcgtttt ttcaggtaat ccgagtagtg atttagaaaa attaatagtg
    15901 cagtacggga taagtgatcg tgttaatttt ttaggttttg tttccgaaag taacttacca
    15961 tcgttatata aaggttcatt aggcttagtt tttccttccc tatatgaagg atttggattg
    16021 cctgtagtgg aggcgatggc atgtggtgtt ccagtattaa cttcaactac gtcatcctta
    16081 cctgaggtgg ctggagaggc tgcgatactt gtagatcctg tgtcggtgtg tgctattagc
    16141 gacgggatta caaaattagt taatgatacg aaactgcgtg aacatttagt ccatgaaggg
    16201 cttttacgag ctaagaagtt tagttggaaa aacgttgtta atgagatcga aatggtactt
    16261 acagaggcat gcaatgaaac taaatgaggc gaaaatatct cttgttcatg aatggctatt
    16321 aagctatgca ggttctgaac aggtttcatc tgcaatatta catgctttcc ctgaggctga
    16381 actatattct gttgttgatt ttttaacaga tgaacaaagg agtaattttc ttggaaagca
    16441 tgcaacaact acatttattc aaaatttgcc aaaagcaaaa aaattatacc aaaaatattt
    16501 accattaatg cctttggcta ttgaacagct tgatttatct gatgcaaaca tcatcattag
    16561 cagcgctcac tctgttgcaa agggcgttat ttctgggcca gatcagttgc atataagtta
    16621 tgttcactcg ccaatccgat atgcatggga tttacaacac cagtatcttc gagagtctgg
    16681 tctgaataaa ggaattaaag gctggttagc taagtggttt ttacataaaa tacgaatttg
    16741 ggactatcgt accgcgcatg gggttgatca ctttatcgct aactctcaat acattgcgcg
    16801 tagaataaaa aaggtttatg gtcgcgaagc ttctgtaata tacccacctg ttgacgtaga
    16861 gaatttcgaa gtaaaagata aaaaagaaga atattatttt acagcatccc gtatggttcc
    16921 ttataagcgt attgatctta ttgttgaagc ctttagcgaa atgccagata aaaaactagt
    16981 cgttattggt gatgggccag agatgaagaa aataaagagt aaggtaaaag ataatataaa
    17041 gttgcttggt taccagcctt tttctgtttt aaaggaacat atgcagaatg ctaaagcatt
    17101 tgtttttgca gcagaagagg actttggaat aattcctgtt gaggctcaag cttgcggtac
    17161 ccctgtcatc gcatttggca aaggtggtgc gttagaaact gttcgtccaa taggtacaga
    17221 agggccaaca ggtattttct ttaagcaaca gacagttgtt tcattacatg cagcaatttg
    17281 cgagtttgaa aaggcttctt cactttttac atctcaagca tgcagagata atgctgaaag
    17341 attttctcgt tcgagattta ataaagaatt tacgaacttt gtagatgaaa agtggaatct
    17401 tttcaaagca gagcaaatta tcaaacgtta atagtggtta attaaatgtc aaaattagta
    17461 ccagtaataa tggctggtgg cacgggtagt cgcttgtggc cgctctcacg cgaacatcat
    17521 cccaaacagt ttttgaccgt tgagggtgag ttctcaatgc tgcaaaacac cattaagcga
    17581 ctgtctccac ttttggttag cgaaccggtt gttatttgta atgatagtca ccgattcctt
    17641 gttgctgaac agcttcgcgc tattgataaa cttgcgaata atattattct tgagcctgta
    17701 gggcgtaata ctgccccagc gatcgcactc gctgcttttt gtgcactcca aaatactgat
    17761 gatgaagatc cattattatt aatcttggct gcggatcatg ttatccgtga tgaaaaggca
    17821 tttattgaag ctattaacca tgctgaatct catgcaactc tcggtaagtt agttactttt
    17881 ggtatcgtcc ctacgcacgc agaaacgggt tatggctata ttcgcagagg tgaggccatt
    17941 gatgcacaag cttatgctgt cgcagaattt gtagagaaac cagattataa tactgcgtgt
    18001 cattatattg aatctgggaa atattattgg aacagtggta tgttcttatt tcgtgcaagt
    18061 agcttcttaa atgaactaaa acaattatct cctgatatat accatgcttg caagagagca
    18121 gttggtcgta ttaatccgga tcttgatttt atccgtattg ataaagagtc atttacttta
    18181 tgtccgagta attccattga ttatgcggta atggagcata cgcaacacgc agtagttgta
    18241 cctatggatg ctgggtggtc ggatgtaggc tcttggtctt cactttggga tatttcacat
    18301 aaagatcagc aacgaaatgt cttgcatggc gatgtatttg cccatagcag tgaagataac
    18361 tatatttact ccgaaagtgc atttattagc acaataggag taaataactt agttatcatt
    18421 cagactgcgg atgcgttatt agtctctgat aaagcttcag tacaagatgt taaaaaagtc
    18481 gttgattatc taaaaaagaa caacagaaac gaacataaaa aacatctgga aaccttccgt
    18541 ccctggggaa aatatactgt aattgatagt ggtgataatt acttggtcaa acgtataagt
    18601 gttaagcctg gtgagaaatt tgttgcgcaa atgcacgagc atcgagtaga gcactggatc
    18661 gtcgtatcag gaaccgctct cgttactaag ggtgaactaa cctttatagt ttcggaaaat
    18721 gaatcaacat ttataccagt taataccatc catgcgctag aaaatccagg agttatccca
    18781 ttggaattaa ttgaaatcca gtcaggtact tatcttagtg aggatgatat catacgcctg
    18841 gaacagcgtt ctggatattc ggagtgagaa attgatgaac agtttttata atagtcgaga
    18901 tattattaat aattctggaa ttgtttttgg aacaagcggt gctcgcggtc ttgtcactaa
    18961 tttttcgcct gaggtttgtg ctgctttctc agtttcattt ttgactgtga tgcaacaaca
    19021 gttctcattc gatactatcg cgctagccat agataatcgt ccgagtagct actcaatggc
    19081 ccaagcttgt gccgctgcac tacaggaaaa aggcatcaat atcgttttct atggtgtaat
    19141 tccgacacca gccttggctt atcaatctat ttctgatggt atacctgcaa ttatggtcac
    19201 agggagccat attccttttg atcgtaatgg cctcaaattt tataggcctg atggtgaaat
    19261 aactaaagat gatgagattt ctattattca tgccgacgct tcatttagcc agacagaatc
    19321 tgaggaattg acagtctctc cagttgcagc tgaaaattat atttcacgat atacttcatt
    19381 gttcccaaca ccttttctga aaaacaagcg tattggtatt tatgagcact caagcgctgg
    19441 acgtgatctc tataagccac tgtttaacgc tttgggcgct actgtcatca ctttagccag
    19501 aagtgatgaa tttgttccta ttgatacgga agctgtgagt gaagatgaca gaaataaggc
    19561 aatcaaatgg gccgcggaat ttcagttaga tgctatattt tctaccgatg gggatggtga
    19621 tcgtcctctt atctcggatg aaaatgggaa ctggctaaga ggggatttgc taggcctctt
    19681 gtgttcactt gagttagccg ctgatgctgt cgctgttcct gtaagctgca atagtacaat
    19741 ttcatcaggt aatttcttca aacatgtgga gcgtactaaa attggttcgc cttatgttat
    19801 agctgcattt tctacattat ctgaaaacta taatcgcatt gtaggatttg aggcaaatgg
    19861 tggtttttta ttaggcagtg atatctgtgt taatcagcag ttacttaaag cgttaccaac
    19921 gcgtgatgcg gtattacccg ctattatgct tctttttaga agtaaggata aaggtattag
    19981 tgcagtagtt gaaaaacttc ctgttcgcta cacccattct aatagattac agaatgttag
    20041 tgccaacaca agcatgtcga tgataaatgt tggactgtcg gacccaaaag cattcttaga
    20101 gtatatcgga ttaaatgatc accatatact atatactgat atgactgatg ggttgagaat
    20161 tacacttaac aataataata ttgtccactt gcgcccttca ggtaacgctc cagagctacg
    20221 ttgctacgct gaagctgact cgccagacga ggcatataaa ttagttgaaa cagtactcgc
    20281 taatattaaa aagcaagtta gtcagaatgt ttaaatacag tagtcataag gcgtttcttt
    20341 ccagaaacgc ctggcttggt tatctggtac ccattttgag ggtgagggtt aatggataat
    20401 attgataata agtataatcc acagctatgt aagatcttat tagcgatatc agatctggtt
    20461 ttttttaatg tggctttgtg gttttctttg ggatgcgtat acctgatttt tgatgaggta
    20521 caacgatttg tcccacagga acagctggat acacgcgtca tatcccattt catactttct
    20581 atagtatgtg tagggtggtt ttgggtacgt ctgcgtcatt acacctaccg caaaccattc
    20641 tggtatgaat tgaaagagat ttttcgtact attgtgatct ttgccgtatt tgatttggcg
    20701 ttaatcgcat ttacgaaatg gcagttttct cgctatgttt gggtattttg ctggtcattt
    20761 gcgctgatat tggtaccctt atttcgtgtg tttacaaaac atttacttaa taagttaggt
    20821 atctggaaaa aaacaactat cattttcggc agcggccaaa atgcacttgg tgcatacagt
    20881 gccctacaaa gtgaagagat gatgggtttt gaagttatcg cattttttga tactgattct
    20941 gttgattgcg agattagctc actacctgta ataaaagatg tggaagaaat ttggaatctg
    21001 aatcgcaccg gtgatgttca ttacattctg gcttatgaat atacagaact cgataaaaca
    21061 caatactggc tccgtgagtt atcaaagcac cattgtcgct cagttactgt ggttccttct
    21121 ttccgtgggt tacctttgta taataccgat atgtccttca tttttagtca tgaagttatg
    21181 ttgctgagaa tacaaaataa tctcgcaaag cggacttctc gttttcttaa acgtactttc
    21241 gacattgttt gctccttatt gattctgcta attgcatccc cgctcatgat ttatttatgg
    21301 tacaaagtta ctcgtgatgg cgggcctgct atttatgggc atcagcgtgt tgggcgaaac
    21361 ggaaaattat tcccatgcta caagtttcgc tcaatggtga tgaactctca ggaagtgtta
    21421 aaagaacttt tggataacga tccggcagca agagctgagt gggataaaga ttttaaatta
    21481 aagaatgatc cacgcatcac tgctgttggg cgttttattc ggaaaaccag ccttgatgag
    21541 ttaccccagt tattcaacgt attaaaaggt gagatgagcc tggttggtcc acggcctatc
    21601 atttcagatg aactggaacg ttattgtgat gacgttgatt attatttgat ggcaaaacct
    21661 ggtatgactg ggctgtggca agttagcggc cgaaatgatg tcgactatga aacacgcgtt
    21721 tattttgact catggtatgt caaaaactgg actctctgga atgacattgc cattttgttt
    21781 aagactgtga aggtcgtttt gcatcgagac ggcgcgtatt gagtgcgtat agacatggat
    21841 gattactacc caaaaggaag catcagtaca ccaattgcta ccttcttact ttgtctctga
    21901 gttaacatgt tagtcactta agccccccgg gggcagcccg gtgggcaacc acacctgaca
    21961 ggagtatgta atgtccaagc aacagatcgg cgtcgtcggt atggcagtga tggggcgcaa
    22021 cctggcgctc aacatcgaaa gccgcggtta taccgtctcc atcttcaacc gctcccgcga
    22081 aaaaactgaa gaagttgttg ccgagaaccc gggtaagaaa ctggttcctt attacacagt
    22141 gaaagagttc gtcgagtctc ttgaaacccc acgtcgtatc ctgttaatgg tgaaagcggg
    22201 cgcaggcaca gatgctgcca tcgactccct gaagccgtat ctggataagg gcgacatcat
    22261 cattgatggt ggtaacacct tcttccagga cactattcgt cgtaatcgag aactgtccgc
    22321 agaaggcttt aacttcatcg gtaccggcgt atccggcggt gaagaggggg cgctaaaagg
    22381 cccgtccatc atgcctggtg gtcagaagga agcctacgaa ctggttgccc cgatcctgac
    22441 caaaatcgct gcagtggcgg aagatggtga accgtgcgtg acctatatcg gcgctgacgg
    22501 cgcgggtcat tacgtgaaga tggttcacaa cggtatcgaa tacggcgata tgcaactgat
    22561 tgcggaagcc tattctctgc tgaaaggtgg cctgaacctg tctaatgaag agctggcaac
    22621 caccttcacc gagtggaatg aaggtgagct gagcagctac ctgatcgaca ttaccaaaga
    22681 catcttcacc aaaaaagatg aagagggtaa atacctggtt gacgtgatcc tggacgaagc
    22741 agcgaacaaa ggcaccggta aatggaccag ccagagctct ctggatctgg gcgaacccct
    22801 gtcgctgatc accgagtccg tattcgcgcg ttacatctct tctctgaaag atcagcgcgt
    22861 ggcggcatct aaggtgctgt ccggcccgca ggccaaactg gctggcgata aagctgagtt
    22921 tgttgagaaa gtgcgtcgcg cgctgtatct gggcaaaatc gtctcctacg cgcagggctt
    22981 ctctcagcta cgtgctgcgt ctgacgagta caactgggat ctgaattacg gcgagatcgc
    23041 gaagattttc cgcgcgggct gcatcattcg tgcgcagttc ctgcagaaaa tcaccgacgc
    23101 ttacgcggag aatgcgggta tcgctaacct gctgctggct ccatacttca aaaacattgc
    23161 tgatgagtac cagcaggcgc tgcgtgatgt cgtggcttac gctgtgcaaa atggtattcc
    23221 ggtaccgact ttctctgctg cagttgccta ctacgacagc taccgtgctg cggtactgcc
    23281 ggcgaacctg atccaggccc agcgtgatta cttcggtgcg cacacttata aacgcatcga
    23341 taaagaaggt gtgttccaca ccgaatggct ggattaa
//
