LOCUS       MF687358               13999 bp    DNA     linear   BCT 02-SEP-2018
DEFINITION  Klebsiella aerogenes strain G5313 polysaccharide gene cluster,
            complete sequence.
ACCESSION   MF687358
VERSION     MF687358.1
KEYWORDS    .
SOURCE      Klebsiella aerogenes
  ORGANISM  Klebsiella aerogenes
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella.
REFERENCE   1  (bases 1 to 13999)
  AUTHORS   Guo,X., Wang,M., Wang,L., Wang,Y., Chen,T., Wu,P., Chen,M., Liu,B.
            and Feng,L.
  TITLE     Establishment of a Molecular Serotyping Scheme and a Multiplexed
            Luminex-Based Array for Enterobacter aerogenes
  JOURNAL   Front Microbiol 9, 501 (2018)
   PUBMED   29616012
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13999)
  AUTHORS   Guo,X., Wang,M., Wang,L., Wang,Y., Chen,T., Wu,P., Liu,B. and
            Feng,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-AUG-2017) Teda Institute of Biological Sciences and
            Biotechnology, Nankai University, 23 Hongda street, TEDA, Tianjin,
            Tianjin 300457, China
FEATURES             Location/Qualifiers
     source          1..13999
                     /organism="Klebsiella aerogenes"
                     /mol_type="genomic DNA"
                     /strain="G5313"
                     /db_xref="taxon:548"
                     /country="China"
                     /collection_date="16-Oct-2014"
                     /collected_by="Shanghai municipal center for disease
                     control and prevention"
     CDS             1..630
                     /codon_start=1
                     /transl_table=11
                     /product="PAP2 superfamily protein"
                     /protein_id="AXR70469.1"
                     /translation="MNWQLVSFFGDSTVLLPSAVVLFAVLALRKASRTLAWQWALLFG
                     ITGTVVCISKLAFMGWGIGIREIDFTGFSGHTALSTAFWPILLWLLTSRAPFSVRCSA
                     VFVGYALAVIVGYSRLMIHAHSVSEVVSGFILGACGSLIFLLLQWRTHSSRTAQISWA
                     GALSMVIIPLVLLNTGAKAPTQSLLGEVATMIGPFDKPFTRADLHKHIY"
     misc_feature    1..13999
                     /note="polysaccharide gene cluster type 7"
     gene            1563..2996
                     /gene="wzi"
     CDS             1563..2996
                     /gene="wzi"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AXR70470.1"
                     /translation="MMKIARIALALGLVASVSSQVYAAGLVQNDNELRNDLAWLSDRG
                     VIHLSLSTWPLSQEEITRALKKAKPSYSSEQVVLARINQRLSNLKADFRVSGYTSTDQ
                     PGTPQGFGQSQPADNSLSLAFNNSGEWWDVHLQGNVEGGERISNGSRFNANGAYGAVK
                     FWNQWLSFGQVPQWWGPGYEGSLIRGDAARPMTGFLMQRAEQAAPETWWLRWIGPWQY
                     QISASQMNQYTAVPHTKIIGGRLTFSPFQSLELGASRIMQWGGEGRPQSFSSFWDGFT
                     GQDNTGTDNEPGNQLAGFDFKFKLEPTLGWPVSFYGQMIGEDEAGGLPSANMYLGGIE
                     GHHGWGKNAVNWYVEAHDTRTNMDRTGYSYTHHIYKDGYYQQGYPLGDAMGGDGQLFA
                     GKIELVTEDNQRWSTRLVYAKVNPKDQSINEAFPHSDTLKGVQLGWSGDVYKSVRLNT
                     NLWYTDADNSDSDDVGASAGIEIPFSL"
     gene            3119..4258
                     /gene="wza"
     CDS             3119..4258
                     /gene="wza"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis export protein"
                     /protein_id="AXR70471.1"
                     /translation="MKKIIVRVSAVAVAISFLAGCTIVPGQGLNSLRKNVVELPDSDY
                     DLDKLVNVYPMTPGLVEQLKPSPVIARSNPQLDNLLKSYEYHIGIGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNSDGTIFYPYIGKVQVAGKTLSQVRQEITNRLTTYIESPQ
                     VDVSVAAFRSQKVYVTGEVANSGKQSITNIPLTVMDAINAAGGLAADADWRNVILTHN
                     GKDTKISLYALMQKGDLSQNHLLYPGDILFVPRNDDLKVFVMGEVGKQTTLKMDRSGM
                     TLAEALGNADGISQNSSDATGIFVIRQLKGDKNGKIANIYQLNAQDASSMILGTEFQL
                     EPYDIVYVTTTPIVRWNRVISQLIPTITGVYNITETARYIKRWPN"
     gene            4258..4695
                     /gene="wzb"
     CDS             4258..4695
                     /gene="wzb"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="AXR70472.1"
                     /translation="MFNSILVVCTGNICRSPIGERYLRLALPNLRIDSAGTGALVDHE
                     ADSTASKIASMHGISLEGHKGRQFTSSIGRQYDLILAMEKSHIEQIGRIAPEARGKTM
                     LFGHWIQQRDIPDPYRKSEDAFSAVYTLIDQAGQLWIKKLGAK"
     gene            4710..6872
                     /gene="wzc"
     CDS             4710..6872
                     /gene="wzc"
                     /note="in cps region"
                     /codon_start=1
                     /transl_table=11
                     /product="putative tyrosine-protein kinase"
                     /protein_id="AXR70473.1"
                     /translation="MPSAIKKPNTVDTNDIDLGRLIGELIDHRKLIIAITSLFTLIAL
                     VYVLFATPIYQADAMIQVEKKQANAILSNLSDILPNGQPQSAPEIALLQSRMIIGKTV
                     DDLNLQAVISRKYFPIFGRGWSRLMGNSDGDINISQFSIEGSTESLPLNFNIEVIDSS
                     HYKFSGDGIEFEGVVGQLKQSSGVSIKVNSIDANPGNEFTLTYISRLQAITNLQNNFI
                     VMDEGKDSGILTLTLTGDNPVQVKKIIDHISYNYLAQNISREAAQDAKSLEFLNQQLP
                     QVRNDLDNAEDKLNAYRRQNDSVDLSLEAKSILDQIVNVDNQLNTLTFREAEVSQLYT
                     KEHPTYKALLEKRKTLQEEKGKLNKKVAEMPKTQQEILRLNRDVDSGRAIYMQLLNRQ
                     QELNIAKSSAIGNVRIIDDGITQPKPVKPNKILVVLLGIILGGMVSVAIVLIRVFLRR
                     GIETPEQLEELGINVYASIPVAERNIKSARYNKGIFDGKHQIQDLLAIDNPADLAIEA
                     IRGLRTSLHFAMMESRNNVLMISGASPNAGKTFVSSNLAAIIAQTGQKVLFIDADLRK
                     GYSHKLFKVDNEKGLSDFLSGQVKSENIIKSVTSVGFDFIPRGMVPPNPAELLMHKKF
                     GELIGWANEHYDLVIVDTPPILAVTDAAIIGNYVGTTLLVTRFEQNTAKEIEVSIKRF
                     EQSGILVKGCILNGVVKKASSYYGYGYNHYGYSYTDDK"
     gene            6979..8403
                     /gene="wbaP"
     CDS             6979..8403
                     /gene="wbaP"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate galactose
                     phosphotransferase"
                     /protein_id="AXR70474.1"
                     /translation="MTLLVRNLTVSLALALSDFLGFVISPWLAIVILSGVMDDVDLTA
                     MSNLDGWIALHWVLAFCCIGWFSVRLRHYFYRKTFWFELKEILRTLTIFAIIEIAVMA
                     FTTWSFSRFLWVLSWFFVLLLVPVFRMLTKRILDAVGFWRRDTWIIGSGTNAHDAYKA
                     ISSERNLGLIIVGFISSTGKVSGGENIDGIRVLENDIDWLNTIDKKTQFIVAVESDQG
                     EVRNTWLRNFMIRGYRYVSVIPTLRGMPLDSTDMSFIFSHEVMIFRVQQNLAKLSSRI
                     LKRVFDIIGSLAIITLLSPVLIYISQKVKKDGGPAIYGHERIGKDGKPFKCLKFRSMV
                     INSKEVLQELLENDPAAREEWDATFKLKNDPRITKIGGFLRRTSLDELPQLFNVLKGE
                     MSLVGPRPIITAELERYNDEVDYYLLSKPGMTGLWQVSGRSDVDYETRVYLDAWYVKN
                     WSMWNDIAILFKTISVVLKKDGAY"
     CDS             8439..9347
                     /codon_start=1
                     /transl_table=11
                     /gene="GT1"
                     /product="glycosyltransferase"
                     /protein_id="AXR70475.1"
                     /translation="MKYYIAIPTYNGGELWQQVVDNLRKNAPENLLVQVIDSSSKDNT
                     PQIAEEAGFDLLTIAGHDFNHGGTRNLAVERVNNQYDVVIFLTQDAIPQPGFIENIVS
                     VFNDDRVACAYGRQLPHDNANPLATHARMFNYPSKGYVCSAEDIPEMGLKTVFMSNSF
                     SAYRLSIFNSLGGFPSDTILCEDMYFTAKAILNGYRVAYVANAIVKHSHNYNAIEEFK
                     RYFDIGVFHKDEAWIRNKIGGAGGEGKKFILSEFSFLLKKAPLWIPIACINNLMKIIG
                     YKIGLQYTRLPKNLIKSLSMHKRYWG"
     CDS             9494..10351
                     /codon_start=1
                     /transl_table=11
                     /gene="GT2"
                     /product="glycosyltransferase"
                     /protein_id="AXR70476.1"
                     /translation="MHSRTPLVSVYITTCNRLEKLKRALRSVKDQSYQNIEIIICDDA
                     SADGTQAYVEGLIREDARIHYFRNDTSKGACAARNLGIFHAQGEYITGLDDDDEFLPE
                     RISQFIEAWDNKYSFICCDFIERFSDGKTKKYYNTNSVEKLTYVDMLFDNVASNQIFT
                     LTERLKAIGGFDIRARRLQDWDTWLRLSHKFGEFIRLPIATYIMHHDHGIDEKRVSKS
                     YPLSSSLIDLRDRNKDIYIDEHLKFMNFIISTEEKKAKPIDSIIWSIKRRTPKYMIKY
                     ALQSFSGNK"
     CDS             10381..11220
                     /codon_start=1
                     /transl_table=11
                     /gene="GT3"
                     /product="glycosyltransferase"
                     /protein_id="AXR70477.1"
                     /translation="MSHSCVVIIVTYNSQKHIQWALDGLETSINKLLVRIVDSGSTDT
                     SYLDALKTKHELIIEKHDNVGFVAGNNLAIERSGNSEWILLLNPDARIEGSDLDKLLD
                     IAGDKRNKEVALFSVPLVRFDINTMKSLSVYDSLGIRCNSYGKWYDIGTNETIKSPPS
                     ELHSNNIDAICGAFMLLRTKALIQCTDKQGNVGFESSYFMYKEDIELSMRLQKNNWGI
                     KLIDNLNAYHCRGWNPSRSKIPYWARYHSAINDLDLSIRYKKRAFPYALTKYLWVKFI
                     ENK"
     gene            11234..12748
                     /gene="orf10"
     CDS             11234..12748
                     /gene="orf10"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AXR70478.1"
                     /translation="MVMKVIDKKCSSYLSILTFLYCIPTFAYADVNADHKTYQIEILK
                     TREEVSAKEADYVYKKLMQRNLQQQIANRDDNTQFGLHGMEIPAVNANGDLTKINQAY
                     SLLARAGVDSLRSFETAWHRVSDSSGNPTNFTQLDFQLKEAKKYNMSHLFVFGYPPAK
                     YTVANNKLSAVQSKYYDKYKDYLHVTLSRLKGYNVKYAELANEVDAPSVWWMKSTPEQ
                     YVQEMKMLKESIAALGLPIKTVAFAATYSRNSLLGGITGGRRFIDKSFQLGIDQYSDA
                     YSIHHFSYGNDDLPGYMRSVQAKHHLSNKEILDTEQLDTASTGRFQSNPYDLIKLFAR
                     GFYYYDMKRVDYFIAKDRYLNNKLYYFGLFDIDWNPKLRLLAYAMAVDSMKGRTLIGI
                     YQPSKGVEAYVLKSKEDSPTKYSIIAWLNDTGTQSNKSVLLEGLSGNADIEHWNLDIA
                     KNIDLTKGVQIDNRPIAIYTNQLPSWVNNNKMKNALYADESRALKSHAPMPTDK"
     gene            12848..13999
                     /gene="wzy"
     CDS             12848..13999
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AXR70479.1"
                     /translation="MALRSPLILVSMFCYMISTRDLIKKFVINALPFCLFLVAAILYS
                     LGNLNAVDNVLGESRDILLSVFVAVFLLSCCDVSDDNRKLIYKTLKATFVFIAIVKVL
                     ILIFSVVTGVPMPLIISWIRDSWNIQMMSLGVEGTFLARLQIPLDSAVPFFLYFVTKE
                     LIFTTEKKYRVITAFVFLLISMLLTLSRAFWAETILFVGLAILFEAGIIRAFRIALVS
                     VITTTLLLLLTPLGSLIFKLIDTRFGKTSMANSASDLERVWQNQMLYNSFIDSPVFGH
                     GLGYFIPNAMRSITTPYLYESQSLSMLMTLGVLGTLVLFLLYVFLCFKTIYNDNNGRL
                     KIIVPAIFLVMWVFSGSVNPLLFGASGGVIIFLTAKTSSLYKRDDAQDL"
BASE COUNT     4311 a   2434 c   3051 g   4203 t
ORIGIN
        1 atgaactggc aattagtctc tttttttggc gatagtaccg tgctgctgcc tagcgcagtg
       61 gtgctgtttg cggtgctggc gctgcgtaaa gcatcccgga cgctggcctg gcaatgggcg
      121 ttgctttttg gcattacggg tactgtcgtg tgtatttcaa agctggcttt tatgggctgg
      181 ggtattggca tacgggaaat cgattttacc ggtttcagcg gacataccgc actttctacc
      241 gctttttggc caatcctttt atggctgtta acctcacggg cgcctttctc cgtccgctgt
      301 agcgccgtat tcgtaggtta tgcccttgct gtcatagttg gctattcccg tttgatgatt
      361 catgcacatt cggtatcgga agtggtgagt ggatttatcc tcggagcctg cgggagtttg
      421 atttttctgc tgttgcaatg gcgtacgcat tcatcgcgca ctgcgcagat ctcatgggca
      481 ggagcgctga gcatggtaat cattcccctc gtgctgttaa acaccggggc taaagcgcca
      541 acacaatcgc tgctggggga agttgcaacc atgatcggcc catttgacaa accgttcacc
      601 agagccgatc tgcataagca tatatattaa tcatgcaatt cggcaaagct gtacattatc
      661 agcctggggt gattggtatg ataaaatgcc agactgcgga caattaaggg ataatagaat
      721 cgtggctttc ataaagatga aacataataa tgttaacaga atacttgaaa gcacgaacta
      781 tcatgatatt gcggctagga tgattcttaa atcaaaacgg aatttcggaa atcagagtta
      841 tctttctgga acccataaac gaagtgggta atgatggcta tcatattttg tagttgactg
      901 ttctatagtt gtttttttgc attaaacatg cggattattt tattttcttt ataatcatgt
      961 ggttatgtat ccatactgtt gcggtggtaa tatcatgccg gatggggaaa gaatccatca
     1021 aataatctta ttaacggatg aaatcctgcc ggggaaaatg aaaaatatca tcttaacaga
     1081 tctgtgtggt taaatttata ctgccatttg caggaagaat ctcgtaaact cggggcggta
     1141 aaaataatag ttgtggttaa ttaaccaaca acaggacgta aagaaaattg ctggataaga
     1201 ggtacagtgc gttggtagct gttaagccaa gggcggtagc gtatccagtt ccccggtcct
     1261 cctcgtattg aaaaggcctg agtaaatcag ccctacgccg agctacgtca tcgacatctg
     1321 atcatgtgca cattattgag gccgtgaaag tagccttggc aaccaatatc gcttacatta
     1381 tgaatgcgtt aagttcacat ccgtttacag caaaccgctc gtactttgag gatgttgtct
     1441 atcgaggcaa tggatcgctg ttgtaaaaaa taggcttgtc gaactcataa gctcctgatt
     1501 cttaaaaatc cccattgccg tacccacctg gtgggaaggg actcgtaaat ggaacttgaa
     1561 caatgatgaa aattgctcgt atcgcacttg ctttgggtct ggttgcatca gttagctcac
     1621 aggtatatgc agctggattg gtgcaaaatg ataatgaact gcgtaacgat ctggcatggc
     1681 tttccgatcg tggggtcatt catctcagtc tttccacctg gccgctcagt caggaagaaa
     1741 tcactcgagc gttgaaaaaa gcaaaacctt catattcctc tgaacaagtc gtactggcgc
     1801 gcatcaatca gcggctttct aatctgaagg cggattttcg cgttagcggc tatacgtcga
     1861 ctgaccaacc aggtacgcca cagggctttg gccaaagcca gccggcagat aactcgctct
     1921 ctctcgcttt taataacagc ggtgagtggt gggatgtgca tctgcagggc aatgttgaag
     1981 gtggcgaacg tattagcaac ggttcacgtt ttaatgccaa tggcgcatat ggtgccgtca
     2041 aattctggaa ccagtggtta tcatttggtc aggtgccgca atggtggggg cctggttatg
     2101 aaggcagcct gatccgcgga gatgcagcca gaccgatgac cggtttttta atgcagcgcg
     2161 cagagcaagc tgctccggag acatggtggc tgcgctggat tggcccgtgg cagtatcaaa
     2221 tttccgccag ccagatgaac cagtatacgg ctgtgccgca taccaaaatc atcggtggtc
     2281 gtttgacctt ctcaccattc cagtcgctgg aacttggtgc ctcacgcatt atgcagtggg
     2341 gtggggaggg gcgcccgcag tcatttagca gtttctggga cgggtttacc ggacaggata
     2401 ataccggtac cgataatgaa cctggtaacc aacttgcagg cttcgacttt aaatttaagc
     2461 ttgaacctac attagggtgg cctgtcagct tctatggcca gatgattggt gaggatgaag
     2521 caggtggttt accttcggca aatatgtacc tgggtggtat cgaaggtcat catggctggg
     2581 ggaaaaatgc ggttaactgg tatgtggaag cgcatgatac tcgtacgaat atggatcgta
     2641 cgggttacag ttatacccat cacatctata aagatggtta ctaccagcag ggttatcctc
     2701 tcggtgatgc aatgggtggc gatggccagt tatttgccgg taagattgaa ctggtaacag
     2761 aggataatca gcgctggagc acccgtttgg tgtacgcaaa ggtcaacccc aaagaccaat
     2821 ctattaatga agcattccct cattcggata ccttgaaggg tgttcaattg ggttggagtg
     2881 gagatgttta caagtcagtt cgcttgaaca ctaatctttg gtacaccgat gccgataaca
     2941 gcgatagcga tgatgttggt gccagcgccg ggattgaaat tccatttagt ttataaaatt
     3001 aacgctgtgc aatgagtata aaaatggctg atgtgattgc tatgtacttt cgaccagtca
     3061 tgacttagca cagcgactca gaaattggca aattttggtt tattaatgat gtgacattat
     3121 gaagaaaata attgttaggg tttcagcagt ggcggtggca atcagttttt tggcaggttg
     3181 tacaatagtt ccgggtcagg ggcttaatag tctgcgcaaa aatgtagttg agcttccgga
     3241 tagtgattat gatctggata agttggtcaa tgtgtatccg atgacacctg gattagtcga
     3301 gcagcttaaa ccatcaccag tgatagctcg ttctaacccg cagttggata atctcttaaa
     3361 aagttatgaa tatcatattg gtattggtga tgtccttatg gtaacagtct gggatcatcc
     3421 cgaactgact acaccagctg gtcagtatcg tagtgccagt gatacaggta actgggttaa
     3481 ttcagacgga acaatttttt atccttacat aggtaaagta caagtcgcag ggaaaacgct
     3541 aagtcaggta agacaagaaa taacaaatcg acttaccact tatattgaaa gtccgcaggt
     3601 tgatgttagc gtcgcagcat tccgctcaca aaaagtttat gtaactggag aggtggctaa
     3661 ctctggtaag cagtctataa caaatatacc gctgactgta atggatgcta tcaatgccgc
     3721 gggtgggctg gcagctgatg ctgattggcg taatgttatt cttacgcata atggtaaaga
     3781 tacaaaaata tcactgtatg cattaatgca gaaaggtgat ttatcgcaaa accacctatt
     3841 atatccaggt gacatattat ttgtcccacg aaatgatgat ttgaaagtct ttgttatggg
     3901 tgaggtcggt aaacaaacga cattaaaaat ggatcgtagt ggcatgactc ttgccgaagc
     3961 acttggcaac gccgatggta tttcgcagaa ttcaagtgat gctacaggta tttttgttat
     4021 ccggcagttg aagggtgata aaaatggcaa gattgcgaac atatatcaat taaatgcaca
     4081 agatgcatct tcaatgatat taggtacaga attccaatta gagccgtatg atattgttta
     4141 tgttacgaca acaccgattg tacgttggaa tagagttatc tctcagctca taccaacgat
     4201 cactggtgta tacaatataa ctgagacggc tcgttatatt aagagatggc ctaattaatg
     4261 tttaattcaa tacttgtagt ttgcacagga aatatttgcc gctcgccaat tggtgagcgc
     4321 tatttacggt tagctctacc aaatttgcgt attgactctg ctggaactgg agccttagta
     4381 gatcatgagg ctgacagtac cgcgagcaaa attgcatcaa tgcatggcat ttcgcttgaa
     4441 ggacataaag gccgacagtt cacgtcatca attgggagac aatatgattt aatccttgcc
     4501 atggaaaaaa gtcatattga gcaaattggc cgtatagctc ctgaggctag aggaaaaacc
     4561 atgctttttg ggcactggat tcaacaacgg gatataccag acccatatcg caagagcgaa
     4621 gatgcatttt cagctgtcta tactttaata gatcaagccg gtcagctctg gatcaaaaag
     4681 ctaggcgcaa aataatcagg aaataggcca tgccatcagc aatcaagaaa cctaatactg
     4741 tagatactaa tgatattgat ttaggtcgac tcattggtga attaatcgat catcgtaaat
     4801 taattattgc cattacatct ttatttaccc ttatcgcgtt ggtgtatgtt ttatttgcaa
     4861 caccgattta tcaagctgat gctatgatac aggtggagaa gaaacaagca aatgcgatac
     4921 ttagtaattt aagcgatatt cttccgaatg ggcaaccaca atccgcaccg gagattgcct
     4981 tattacagtc aaggatgatt atagggaaaa cggttgatga tctaaattta caagccgtaa
     5041 tatccagaaa atattttcca atatttggtc gaggatggtc gcgcttaatg ggaaatagtg
     5101 atggtgacat caatatttcg caatttagta tcgaaggtag tacagaaagt ttgccattga
     5161 atttcaatat tgaagtaata gatagctcgc attataagtt cagtggcgat ggtattgaat
     5221 ttgaaggcgt tgtcggacaa ctgaagcaaa gctcaggggt ttcgataaaa gtcaattcta
     5281 ttgatgcaaa cccagggaat gaatttacat taacatatat atcccgactg caagcaatta
     5341 cgaatttgca aaataacttc attgtaatgg atgaaggtaa agattctggc atattgacat
     5401 tgactttaac aggtgataat cctgtgcaag ttaagaaaat catcgaccac attagctata
     5461 actatctagc ccagaatata tcaagagaag cggcgcaaga tgcgaagagc cttgaatttt
     5521 tgaatcagca gctgcctcaa gtaagaaatg atttggacaa tgctgaagac aagttaaatg
     5581 cgtatagacg tcaaaatgat tcagtagact tgtcgctaga agcaaaatct atacttgacc
     5641 aaatagttaa cgttgataac cagttaaaca ctttaacatt ccgagaagct gaagtttctc
     5701 agttatatac aaaagagcat cctacttata aggcattgct tgagaaaaga aaaacgctgc
     5761 aggaagaaaa aggaaagcta aataaaaaag tagctgaaat gccgaaaacg cagcaagaaa
     5821 tattaaggct aaatcgagac gttgattccg ggcgagcaat atacatgcaa ttgcttaatc
     5881 gtcaacaaga actcaatatt gcaaaatcga gtgctatagg caatgtgaga ataattgatg
     5941 atggcatcac gcaaccaaaa cctgtaaaac ctaataagat cttggttgtg ctgctaggga
     6001 ttattctcgg cggtatggtt tcagtagcca ttgtactaat ccgggtgttc ttacgacgtg
     6061 gtattgaaac tccagagcag ttggaagagc ttggcattaa tgtatatgca agtattcctg
     6121 tcgcagaaag gaatattaaa agcgccagat acaataaagg gattttcgac ggcaagcatc
     6181 aaattcagga tctgctagct atcgataacc ctgcagattt ggcaattgaa gctattagag
     6241 gacttcgtac aagtttgcat tttgccatga tggagtctcg aaataatgta ctgatgattt
     6301 ctggtgctag cccaaatgcc ggtaaaacat ttgtaagttc aaacttagca gctataatcg
     6361 cgcaaactgg ccaaaaagta ctatttattg atgccgattt acgcaaaggt tattcccata
     6421 aactatttaa agttgataat gaaaaggggt tatccgactt cttatcaggg caagttaaaa
     6481 gcgaaaacat catcaaatcg gtaacttctg ttggattcga ttttattcct cgaggtatgg
     6541 tgccgccaaa tcctgcggag cttttaatgc ataaaaagtt tggtgagtta attggttggg
     6601 ctaatgaaca ttatgactta gtcattgtgg atacaccgcc aatactggca gtcactgatg
     6661 ccgcgataat tggaaactat gtaggcacca ctctactcgt aacacgcttt gagcagaata
     6721 cagcaaaaga aatagaagtc agtattaaaa ggtttgagca gagcggtatc ttggttaaag
     6781 gttgtatatt aaatggtgta gttaaaaaag ccagcagtta ttatggatac gggtataatc
     6841 attatggtta ctcgtataca gacgacaaat aatatcctat tgcggccagt ctaagattgg
     6901 ccgctgatta aaattcgaat tatttctaga gttaatatct aaatcatacc tcactaaata
     6961 aaatattgag agggaatcat gacgcttctc gtcagaaatt tgacagtcag tcttgcattg
     7021 gcattatctg attttttagg ttttgttata tcaccatggt tggctatagt tattctttcc
     7081 ggagttatgg acgacgtaga cctaactgca atgagtaatc tggatggctg gattgcatta
     7141 cactgggttt tagcattttg ttgcattgga tggttttcag ttcgattaag acattacttc
     7201 tatagaaaga cattttggtt tgaactaaaa gaaattttgc ggacactgac tatttttgca
     7261 atcatcgaaa tagctgtaat ggcgtttacg acatggtcat tttcacgctt tttatgggta
     7321 ttaagttggt tttttgtcct tcttttagtt cctgtattca gaatgttaac aaaacgtatt
     7381 ctggacgctg taggcttttg gcgacgcgat acctggatta taggaagtgg tacaaatgct
     7441 cacgatgctt ataaagcaat cagcagcgaa agaaacttag gcttaatcat tgtcggtttt
     7501 atcagcagta caggtaaagt ctcagggggg gaaaatattg atggaatccg agtcctggaa
     7561 aacgacatag attggttgaa tactattgat aaaaaaacac aatttatagt tgctgtcgaa
     7621 tcggaccaag gtgaggtaag aaacacttgg cttagaaact tcatgattag aggataccga
     7681 tacgtatctg tcattcctac gctccgcggg atgccattag atagtacaga tatgtcattt
     7741 atttttagtc atgaggtcat gatttttcga gtacaacaga acctggctaa attatcctca
     7801 agaatattaa aaagagtctt tgatattatt ggttccctcg cgattatcac cttgctttca
     7861 cctgtcctta tatacataag tcagaaagtg aaaaaagatg gtgggccagc tatttatgga
     7921 catgaaagaa ttggcaaaga cggaaaacca ttcaagtgtt taaaattcag gtctatggtg
     7981 attaactcca aagaagtgtt acaggaatta cttgaaaatg atcccgctgc aagagaagaa
     8041 tgggatgcaa cttttaaatt gaagaatgac cctcgtatta caaaaattgg tggttttcta
     8101 agacgtacaa gtctagatga gttgcctcaa ttatttaatg tattgaaggg ggaaatgagt
     8161 ttagtagggc cgagaccaat tattacggct gaacttgaaa gatataatga tgaagttgat
     8221 tattatttat taagcaaacc aggaatgact ggcctttggc aggtaagcgg gcgcagtgat
     8281 gtggattatg aaaccagagt atatttagac gcctggtacg ttaaaaattg gtctatgtgg
     8341 aacgatattg ctattttgtt caaaaccatt agtgttgtat taaaaaagga tggcgcatac
     8401 taattgcatc attatggtat gtcagatagg aaattaatat gaaatattat atagcaatac
     8461 caacatacaa tggtggcgaa ctttggcaac aggttgtcga taaccttaga aaaaatgccc
     8521 ctgaaaattt attagtgcaa gtaattgatt caagtagtaa agataatacg ccacaaattg
     8581 cggaagaagc gggatttgat ttacttacta ttgcaggcca tgatttcaac catggcggaa
     8641 caagaaatct tgcggtagaa agagtaaata atcagtatga tgtggtaatt tttctcactc
     8701 aggatgcgat tccacaacca ggattcatag agaatattgt ttctgtattt aatgacgata
     8761 gagttgcttg cgcatacggc aggcaactcc cgcatgataa tgctaatcct ttagcaacac
     8821 atgccagaat gttcaattat ccttccaaag gatatgtttg tagtgcagaa gatatacctg
     8881 agatgggatt gaagacagtt ttcatgtcta attccttttc agcatataga ttatcaattt
     8941 ttaattcgct gggaggtttt ccttccgaca caatcctttg tgaagatatg tattttacag
     9001 caaaagctat tctgaatgga tacagagttg cctatgtagc aaatgcgata gttaaacact
     9061 ctcacaatta caatgcgatt gaagagttta aacgctattt tgatataggc gtgtttcata
     9121 aggatgaagc atggataaga aataaaatag gcggcgctgg gggcgagggt aaaaaattta
     9181 ttttatctga gttttcgttt ttattgaaaa aagccccttt gtggattccg atagcttgca
     9241 ttaataactt aatgaaaata ataggttata aaattggctt gcagtatact cggttgccga
     9301 aaaatctaat caagtccctc agtatgcata aacgttactg ggggtaataa gtattcaaca
     9361 attggcgtga gatgaaatgc catctggaaa ttagaatcgc taagcgcgtc atcgttgctg
     9421 tttcacgaat ctattcatta acgctgcaag gtgaggtctc aggttcgttc gtcaatttaa
     9481 gagagagtgt aaaatgcata gcagaacgcc actggtaagt gtttatataa caacctgtaa
     9541 ccgcctggaa aaactaaaac gcgcacttcg ttcggttaaa gaccaaagtt atcaaaacat
     9601 tgagataatc atttgcgatg atgcttctgc tgatggtacc caagcatatg tagaaggact
     9661 gattcgagaa gacgctcgta ttcactattt ccgcaacgac acaagtaaag gtgcttgtgc
     9721 tgcgaggaat ctaggtattt ttcacgcgca aggtgagtat attaccggct tagatgatga
     9781 tgatgagttt ttgcctgagc gtatatctca gtttattgaa gcttgggata acaagtattc
     9841 attcatctgt tgtgacttta ttgaacgatt ttctgatggg aaaaccaaaa aatattataa
     9901 cacgaacagt gttgaaaaat taacatatgt cgatatgtta ttcgataatg tcgcatcaaa
     9961 ccagatattc acattaacag aaagattgaa agctataggt ggatttgaca ttagagctag
    10021 aaggctgcag gattgggata cttggctaag gctttcgcat aaatttggtg agtttattcg
    10081 gttgccaata gcaacatata taatgcacca tgatcatggt atagatgaaa aaagagtctc
    10141 caaaagttac cccttgagtt catcgcttat tgatttaaga gatcgaaata aagatatata
    10201 tattgatgaa catttgaaat ttatgaactt tataatttca accgaggaga aaaaggcaaa
    10261 gcctatcgat tctattatat ggagtattaa aagaagaaca cctaagtata tgattaagta
    10321 tgcgcttcag tctttttctg gtaataaata attaaagtat ctgctcaagg gaagccttaa
    10381 atgtctcact catgtgtcgt aatcattgtt acatataata gccaaaagca tatacagtgg
    10441 gctcttgatg ggcttgaaac atcaataaat aaactcttag taagaatagt tgattctggc
    10501 tctactgata cttcttattt agatgcttta aagacaaaac atgaactgat catagagaaa
    10561 catgataatg tagggtttgt agcaggcaat aacttagcga ttgaaagatc aggaaactct
    10621 gaatggatat tgctattgaa tcctgatgca agaattgaag ggtctgattt agataaatta
    10681 ctcgacattg caggcgataa acgaaataaa gaagtcgcat tattttccgt gcccttggtt
    10741 cgatttgata taaatacaat gaaatcatta tctgtttatg attcattggg tatacgatgc
    10801 aattcctacg gtaagtggta cgatattggc actaatgaaa ctatcaaatc tcccccatcg
    10861 gagttgcaca gtaacaatat cgatgccatt tgtggtgctt ttatgctttt acgtactaag
    10921 gctcttatcc aatgtactga caaacaggga aatgttggct ttgaaagtag ctacttcatg
    10981 tataaagaag atattgagtt atctatgcgt ttacaaaaga acaactgggg tattaagctc
    11041 atagacaact taaatgcata tcattgtcga ggttggaatc cttcaagaag taaaatacct
    11101 tattgggctc gatatcattc agccataaat gatctcgatc tctcaataag atataaaaaa
    11161 agagcctttc cttatgcgct aactaaatac ttatgggtca aattcatcga gaataagtaa
    11221 aatatttgag gaaatggtta tgaaagtaat agataaaaaa tgctcatcat atctttcaat
    11281 tcttaccttt ttgtattgca tacctacgtt tgcttatgct gatgtaaatg ctgaccataa
    11341 aacttatcaa attgaaatat taaaaacacg agaagaagtt tcagcgaaag aagctgatta
    11401 tgtatataaa aaattaatgc aacgaaattt gcagcagcag atagcgaatc gggatgataa
    11461 tactcaattt ggattgcatg gaatggaaat tccagcagta aatgccaatg gggatctgac
    11521 aaaaataaat caggcatatt ctttactcgc gcgggcaggc gtggattctt tacgtagttt
    11581 tgagacagca tggcatcgcg tgagtgattc ttctgggaat ccaacaaatt tcacgcaact
    11641 tgattttcag ttgaaagaag caaaaaagta caatatgtcg catctatttg tttttggtta
    11701 tccgccagcc aaatatacag tggcaaataa taagctatca gctgtacaat caaaatatta
    11761 tgataaatat aaagattatc tccatgtaac cttgtccaga cttaaaggtt ataatgttaa
    11821 atatgcagaa ttagctaatg aagttgatgc accgagcgta tggtggatga aatccacgcc
    11881 tgagcaatat gttcaggaaa tgaaaatgtt aaaagaatct attgctgcat tggggttgcc
    11941 aataaagaca gttgcttttg ctgcaacata ttcaagaaat agtctattag gtggaatcac
    12001 aggcggaaga agatttattg ataaaagctt ccaactggga attgatcagt acagcgatgc
    12061 atattctatt catcatttct cctatgggaa tgatgattta cccggttata tgagaagtgt
    12121 acaagcaaaa catcacttat ctaataaaga aatacttgat acagagcagc tggatacagc
    12181 atcaacaggt agatttcagt caaaccctta cgatctcatc aagttatttg caagagggtt
    12241 ttattattat gacatgaaac gagttgatta ttttatagct aaagatagat atttaaataa
    12301 taaactttac tactttggtc tgttcgacat tgattggaac ccgaagttaa gattattagc
    12361 atatgctatg gcggtagatt caatgaaagg tcgaactctt atcggcattt atcaaccttc
    12421 gaaaggagtt gaggcatatg tattaaaatc aaaagaagac tcgccgacta aatactccat
    12481 aatagcatgg ttgaatgata ctgggactca gtcaaataaa agtgtactcc tggaagggtt
    12541 gtccgggaac gctgatattg agcattggaa cttggatata gctaaaaata ttgatttgac
    12601 caaaggtgtt caaattgata atcgacctat cgcgatttat acgaatcagt taccttcgtg
    12661 ggttaataat aataaaatga agaatgcact ttacgctgac gaaagtcggg cacttaaaag
    12721 tcatgctcct atgcctactg ataaatgatt gtttcaactt tttcaacctc attgttggat
    12781 ttataagtgg gattaaactt caatgaaaat aaaaaaaaca ctttttataa aaatatttat
    12841 atatttaatg gcattgcgaa gtccattaat acttgtcagc atgttttgct acatgatctc
    12901 tacccgcgat ttgattaaaa aatttgttat taatgcactt cctttttgtt tgtttttagt
    12961 tgctgcgatc ctatattcct tagggaattt aaacgcagtt gataatgttc ttggtgagtc
    13021 gagggatatt ctcttatctg tgtttgttgc tgttttctta ttatcctgct gtgatgtttc
    13081 agatgataat agaaaactta tctacaaaac tttgaaagcg acatttgttt ttatcgcaat
    13141 tgtaaaagtt ttgatattga tattttccgt ggtcactggt gtcccaatgc cattaatcat
    13201 atcgtggatt cgtgactcct ggaatataca aatgatgtct ttgggggtcg aagggacatt
    13261 tctggctcgc ttacaaatcc cattagattc agcggttcct tttttcttgt attttgttac
    13321 taaagaatta atttttacca ctgaaaaaaa ataccgcgtg ataacggcat ttgtttttct
    13381 attaatatca atgttactta cgctatcacg agctttttgg gctgagacaa ttttatttgt
    13441 tggactggct attctttttg aagcaggtat aattcgggca tttagaatag cattagtgtc
    13501 tgttattaca actacattat tactgctgct gacaccgctt ggctcattaa tctttaagct
    13561 aattgatacc aggtttggca agacaagcat ggcaaactca gcttctgact tagaacgagt
    13621 ttggcaaaac caaatgttat ataattcctt tattgattcg cctgtctttg gtcatggttt
    13681 aggatatttt ataccaaatg caatgcgttc tataactacg ccatatttat atgagagtca
    13741 gtcgttatca atgcttatga cattaggcgt gctaggaacg ctagtgttat tcctgttata
    13801 tgtctttctc tgttttaaaa ctatctacaa tgataataat ggacgtttga aaattatagt
    13861 gcctgctatt tttctagtta tgtgggtttt ttctggctcc gttaacccct tattattcgg
    13921 tgcttcaggt ggtgtgataa tatttttaac agcaaaaaca tcatctttat acaaaagaga
    13981 cgatgcccaa gatctctga
//
