LOCUS       AB811599               21154 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli DNA, O-antigen biosynthetic locus, strain:
            Bi8337-41.
ACCESSION   AB811599
VERSION     AB811599.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 21154)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..21154
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="Bi8337-41"
                     /db_xref="taxon:562"
                     /note="serogroup:O10"
     gene            <1..902
                     /gene="wcaM"
     CDS             <1..902
                     /gene="wcaM"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="BAQ00612.1"
                     /translation="AILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDSDILISD
                     HVIERINCTNDKINWGIGIGLSGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENG
                     KHFVIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKG
                     KYLSIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQ
                     HLFMRNIKVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAMNERGQSSVD
                     IDRINHHIVNVEKINFRLPERRE"
     gene            1065..1970
                     /gene="galF"
     CDS             1065..1970
                     /gene="galF"
                     /note="O010_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ00613.1"
                     /translation="MDEIMTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLELRVKRQLLAEVQSICPPGVT
                     IMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGR
                     YVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQA
                     FVKYGLRNLKEGAKFRKGIEKLLSE"
     gene            2342..3427
                     /gene="rmlB"
     CDS             2342..3427
                     /gene="rmlB"
                     /note="O010_02"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6 dehydratase"
                     /protein_id="BAQ00614.1"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLV
                     DVSDSERYVFEHADICDAAAMARIFALHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSALDGDKKNSFRFHHISTDEVYGDLPHPDEVNNKEELPLFTETTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KALPIYGKGDQIRDWLYVEDHARALYTVVTEGKAGETYNIGGHNEKKNIDVVLTICDL
                     LDEIVPKEKSYREQITYVADRPGHDRRYAIDAEKIGRELGWKPQETFESGIRKTVEWY
                     LANAKWVDNVKSGAYQSWIEQNYEGRQ"
     gene            3427..4326
                     /gene="rmlD"
     CDS             3427..4326
                     /gene="rmlD"
                     /note="O010_03"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAQ00615.1"
                     /translation="MNILLFGKTGQVGWELQRALVPLGNLIALDVHSTDYCGDFSNPE
                     GVAETVRSIRPDIIVNAAAHTAVDKAESEPNFAQLLNATSVEAIAKAANEVGAWVIHY
                     STDYVFPGTGEIPWLETDATAPLNVYGETKLAGEKALQEYCAKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKELEELAVINDQFGAPTGAELLADCTAHAIRVALNKPDVAGLYHLVAS
                     GTTTWYDYAALVFEEARKAGIPLALNKLNAVPTTAYPTPARRPYNSRLNTEKFQQNFA
                     LVLPDWQVGVKRMLNELFTTTAI"
     gene            4384..5262
                     /gene="rmlA"
     CDS             4384..5262
                     /gene="rmlA"
                     /note="O010_04"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="BAQ00616.1"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGG
                     DDCALVLGDNIFYGHDLPKLMDAAVNKESGATVFAYHVNDPERYGVVEFDKKGTAISL
                     EEKPLQPKSNYAVTGLYFYDNGVVEMAKNLKPSARGELEITDINRIYMEQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFITTIEERQGLKVSCPEEIAYRKGFIDAEQVKILAEPL
                     KKNAYGQYLLKMIKGY"
     gene            5267..5809
                     /gene="rmlC"
     CDS             5267..5809
                     /gene="rmlC"
                     /note="O010_05"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="BAQ00617.1"
                     /translation="MNVIETEIPDVLIFEPKVFGDERGFFFESFNQKVFEEAVGRKVN
                     FVQDNHSRSVKGVLRGLHFQIKPYSQAKLVRCVKGEVYDVAVDIRPESSTYCKWVGVF
                     LSAQNKKQLWIPEGFAHGFVVVSDEAEFLYKTTNYYMPSAEGCIRWDDPALNIDWPMK
                     TNELILSDKDKNAERYYFKK"
     CDS             5819..6952
                     /note="O010_06"
                     /codon_start=1
                     /gene="fdfA"
                     /transl_table=11
                     /product="putative aminotransferase"
                     /protein_id="BAQ00618.1"
                     /translation="MIPFNKPYLQGNELTYIAEAVSNGKISGDGIFTKKCHEFFERKY
                     GFKKALLTTSCTDALEMAAILLDIKPGDEVIAPAYTFVSTVNAFALRGAKIIFADSYD
                     DNPNMDPESASKLITNKTKAIIVVHYAGVACDMDKFLELSKEYKIHIIEDAAQAIDSY
                     YKDRPLGSIGTFGTFSFHETKNIISGEGGLIALNNDEYFHRAEIIREKGTNRASFFRG
                     EVNKYGWVDIGSSFLPSDMIAAYLYAQLENVDAIQNKRKELWREYYDNLKQLANSGYI
                     QLPIIPEYATNNAHMFYIVCSDLKKRSELISYLKESGIHSVFHYLSLNKSEYYLKQNK
                     KISLQNSDKFADCLLRLPMYYELECKQVNYISEKIAHFFKKHA"
     gene            7023..8543
                     /gene="wzx"
     CDS             7023..8543
                     /gene="wzx"
                     /note="O010_07"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAQ00619.1"
                     /translation="MNREYKLLIYIYSVRIYTALVTIFLIPILIGEIGLEAYGLIGFF
                     AVLQACLSILDAGLGGVITREAIVSRKNQGTYKKFSILYKKIIIFFIIVSLLLVTCGW
                     WVSEQYSTSWLNTKLDKSVVVFCTTVMFWVFALRYMQGPFRSILLSNESQIILTTINL
                     FTITLSQPLTIFLMKYLDEGIKFYFLMQLISSAIGCISMVLYSEKIRRKVLFLCPLEE
                     DSIKSEDTSVRKLIVFALQLSTLSILWVLVNQSDKLALTKYSTLTEYGIYSVAVSIIS
                     VLAILSDPLNQYLQPRLTRYYHQNNLKEYSKLFSGALKFICILTIPLSVFLFFYGKDV
                     LFIWSGDETLSIKAAKYLPWLFIGGVFSIYSNFVFLLLYSFGELKRHTIVYALFSLFV
                     IPANVFLAKQYLGQGTSIFFGISSMFLFLLWGGYNFAKFFVKGLRVIYVYIIPLFLVE
                     IIYFKTSTAFPYNHTVKWTLFIQLFSVGLVGLALAIIYCKLVDKKNSQVILKIVDK"
     CDS             8540..9451
                     /note="O010_08"
                     /gene="wccF"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ00620.1"
                     /translation="MNIYIYASSYDENSGGSVVLHRLCHIINKHSSHSAYLVKLDPFH
                     YGKKTIRKYLSKLKWELCNKFKFKTNDDWDTPVWHKLNNIPSNSVVIYPEIINGNPLK
                     IKNVVRWLLHQPGHHTNVIDYGKNELYFKFNSAIHDFENDGSYTAANELKVIYYPVQI
                     YNEKLNQERDIECCYLVRKGFYKKSVHPPKAIKIDGLTHQEIADVFRRSQKFISYDDY
                     TAYSIFSVLCGCPSYVVPTEGQTVNDWYPDERDRYGISYGFTDEQAKWAEETKDRVYR
                     HIINEHNKSIDRVINCLQEIEVFFGKN"
     CDS             9574..10494
                     /note="O010_09"
                     /gene="wfgI"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ00621.1"
                     /translation="MIEQDKCIIAVVVLFRPEIARIHGLLKSIIMQVDKVVLIDNTDK
                     SNLIIPDSEFESYGEKIEHYRLNNNLGIAKAQNIGIHYAEKSKASHILFLDQDSIVSE
                     GMVKTLLINERELLNSGKKVAVLGPAFKDEKTGKVTGAIHISPFYKTKLCHGVHPLET
                     DFLISSGSLVRMEVLQKIGFMDEELFIDFVDIEWCERAKKMGLRSYVVPDIVMMHNIG
                     NEAKRILGKNVIMHSDFRHYFIVRNSIYLILKDKLSFNHCVYLFIRLPLFIAVRTLNS
                     SSKLKKIKLLATAIKDGVVDKMGKGYFSNS"
     gene            10564..11607
                     /gene="wzy"
     CDS             10564..11607
                     /gene="wzy"
                     /note="O010_10"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAQ00622.1"
                     /translation="MFLYLSIFICISILSFFPYQKYLLKAIMIFLLLMCAFRSEFVDR
                     DYTNYITLIFESANNLFYPIEISFKVISFIAVNMLGGYYFVFIIFALISIYLKYNIIK
                     KSSPFLLLSVLVYYSNTFLLQDMTQIRAGVAGAIVLYSVLQYAKNKNIMSFVMLIFLA
                     STFHITTLLFFIVLAFDTNVVSRRYIFIYFLTLFGACCCYYAGVNFLTLLRYIPVSYV
                     QYKFSDYISQSQGADFVPVNIFSVTQLLHLLIVILSFIFSRKKILSRDKVLVIKIYSL
                     SPLAFIILSSMPVFALRVSELFAISEIILLPFLPLLFRQKQFAKLAIIGICFIMFYIN
                     IYHLEILNEYSAL"
     CDS             11639..12631
                     /note="O010_11"
                     /gene="wekN"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ00623.1"
                     /translation="MFGTIDEYKSKSVLIMRKKMKLKSMAVLLSSYNGEKYIGEQLDS
                     IIKCYRDFDLHIHIRDDGSVDSTCEIIKEYISKNDSIFLYEGDNVGVIASFLWLVENV
                     GDYDYYAFCDQDDVWEPLKLIAATTKIIKYNQDIAIGYCSSYNYVDKELNHIGRYNSQ
                     SDFSLNNILIENCAPGCTFVFNQSLRKLYLDINEANMANRIVMHDWFFLILARTFGHL
                     IYDHNSYLSYRQHDNNVVGIKSGFKNILCNRLKQFKKYKQNGRHLLSLQIDLVSLYCL
                     KHNKEAAYEISHGFVESQASLVKRLRYVFSGYVKRVRFIDDVLFKVLFIIGWYK"
     CDS             12641..13771
                     /note="O010_12"
                     /gene="wbdH"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ00624.1"
                     /translation="MPRKKILLVANTLWSVYNFRKGLIKSLIEKGYDVTIVAPEDDHL
                     EKIVDLGCKFESISVSSQGKNPLKDLMLLFKLIKIYKKIKPDFIFHYTIKLNIYGSIA
                     AGITNCKSIAVTTGLGFVFNKETLLTKFITQLYAFSFRFAKEVWFLNEDDRNVFLRKR
                     IINESKSFILASEGVDTSYFTPSQVSCKTKYNDNVTFLLIARMLWEKGIGVYIDAANI
                     LKSEFPGIRFQLLGACDSQNPGAITRQEIENWQIKGIIEYLGVESDVRPHIISADCIV
                     LPSFYREGVPRVLMEASSMCKPIITTNNVGCKDVVVDGETGYLCNVRDYIGLANVMRK
                     FIELTPQERETMGKKGRDYIIKNFDERKIIKIYHDTLTKYIS"
     CDS             14023..14583
                     /note="O010_13"
                     /gene="fbfB"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyltransferase"
                     /protein_id="BAQ00625.1"
                     /translation="MSFLSDSELRKIGFKKLGKNVKISEKASIYNPEKIEIGDNSRID
                     DFCLLSGKISIGNNVHIAAYCNIAGGIEGITFDDFSGLAYGCHVFSQSDDYTGRTLTN
                     PTIPKKYKKEIIKKVIIGKHVIVGTNSLVFPGVTIEEGCSIGAMTMVTKSTKAWGCYF
                     GIPAKRIKERKKDLLELEQLFHKENK"
     CDS             15110..16246
                     /note="O010_14"
                     /gene="ISAs1"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase of ISEc1"
                     /protein_id="BAQ00626.1"
                     /translation="MELKKLMERISVIPDYRQAWKVEHKLSDILLLTIGAVISGAEGW
                     EDIEDFGETHLDFLKQYGDFENGIPVHDTIARVVSCISPAKFHECFINWMRDCHSSDD
                     KDVIAIDGKTLRHSYDKSRRRGAIHVISAFSTMHSLIIGQIKTDEKSNEITAIPELLN
                     MLDIKGKIITTDAMGCQKDIAEKIQKQGGDYLFAVKGNQGRLNKAFEEKFPLKELNNP
                     EHDSYAISEKSHGREEIRLHIVCDVPDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKE
                     PEMTVRYYISSADLTAEKFATAIRNHWHVENKLHWRLDVVMNEDDCKIRRGNAAELFS
                     GIRHIAINILTNDKVFKAGLRRKMRKAAMDRNYLASVLAGSGLS"
     CDS             16729..16983
                     /note="O010_15; sulfatase"
                     /gene="wccH"
                     /pseudogene="unknown"
                     /codon_start=1
                     /transl_table=11
     gene            17118..18524
                     /gene="gnd"
     CDS             17118..18524
                     /gene="gnd"
                     /note="O010_16"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ00627.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKAGVFHTEWLD"
     gene            18773..19939
                     /gene="ugd"
     CDS             18773..19939
                     /gene="ugd"
                     /note="O010_17"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ00628.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQADKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVEINPYAVMVVKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            20029..21063
                     /gene="wzz"
     CDS             20029..21063
                     /gene="wzz"
                     /note="O010_18"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ00629.1"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLV
                     QLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGS
                     AVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQSLPLAVSYVGETP
                     EGAQKQLAKYIQQVDEQVYEELEQDLKDNIALRTKNLQDSLKTQEVVAQEQKDLRIRQ
                     IQEALQYANQAQVTKPQIQQTQDVTQDTMFLLGSEALESMIKHEATRPLVFSSNYYQT
                     RQNLLDIDNLDVDKLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLG
                     RNALRNYNAK"
BASE COUNT     6579 a   3642 c   4506 g   6427 t
ORIGIN
        1 acgccatctt acgccaggga tttcataacc agattatcgg tgccaacatc accaattgta
       61 agttcagcga cttacagggg gacgctattg aatggaacgt ggcgattaac gacagtgata
      121 ttttgatctc cgaccatgtc atcgagcgca tcaactgtac taacgacaaa atcaactggg
      181 gcatcggcat aggtctttcg ggtagtacct acgataacaa ctacccggaa gaccaggcag
      241 tgaaaaactt tgtcgtggcg aatatcacgg gatcggattg tcggcagttg atccatgttg
      301 aaaatggtaa acattttgtt attcgtaata tcaaagcccg caatatcaca ccggatttca
      361 gtaagaaagc aggtattgat aacgccacag tcgctattta cggttgtgac aatttcgtga
      421 ttgataatat tgaaatgatt aatagcgccg ggatgttaat cggctatggg gtaattaaag
      481 gcaaatatct ctcgataccg caaaatttcc gagtgaataa tattcagctg gataacaccc
      541 atcttgctta taaattgcgc ggcatccaaa tctctgccgg gaatgccgtc tcctttgtgg
      601 cactgactaa cattgagatg aagcgtgcgt ctctggagtt acacaacaaa ccgcaacatc
      661 tttttatgcg taatatcaaa gtgatgcagg aatcctctgt tggaccagca ttgagcatga
      721 actttgacat gcgcaaagac gttcgcggtg tctttatggc gaaaaaagaa acactgctgt
      781 cacttgcaaa tgttcatgcg atgaatgaaa gagggcaaag ctccgtcgac atcgacagga
      841 ttaatcacca tattgttaat gtggaaaaga ttaactttag attgccggaa cggagggagt
      901 agatttgcga ccattcctgg aaaaatggag ccatacttag gaacaatgct actgcaatcc
      961 acaacgaagc ggcgtaacat cacaagtaat tcagtaatca attcagggta attgatgctg
     1021 gcgaaaaaaa tcgaacaagc tataattcag caaccatttt acaggtggat gaaataatga
     1081 cgaatttaaa agcagttatt cctgtagcgg gtcttgggat gcatatgttg cctgccacta
     1141 aggcgattcc caaagagatg ctaccgatcg tcgacaagcc aatgattcag tacattgttg
     1201 acgagattgt ggctgcaggg atcaaagaaa tcctcctggt aactcacgcg tccaagaacg
     1261 cggtcgaaaa ccacttcgac acctcttatg aattagaatc tcttcttgaa ctgcgcgtga
     1321 agcgtcagct gctggcggaa gtgcagtcca tctgtccgcc gggcgtgacc attatgaacg
     1381 tgcgtcaggg cgaaccttta ggtttaggtc actccatttt gtgtgcgcgg cctgccattg
     1441 gtgacaatcc atttgtcgtg gtgctgccag acgttgtgat cgacgacgcc agcgccgacc
     1501 cgctgcgcta caaccttgct gccatgattg cacgattcaa cgaaacgggt cgtagccagg
     1561 tgctggcaaa acgtatgccg ggtgacctct ctgaatactc ggtcatccag accaaagaac
     1621 cactggaccg tgaaggtaaa gtcagccgca ttgttgaatt tatcgaaaaa ccggatcagc
     1681 cgcagacgtt ggactcagac atcatggccg ttggtcgcta tgtgctttct gccgatattt
     1741 ggccggaact tgaacgcact cagcctggtg catgggggcg tattcagctg actgatgcca
     1801 tcgctgaact ggcgaaaaaa cagtccgttg atgccatgct gatgacaggt gacagctacg
     1861 actgcggtaa aaaaatgggc tatatgcagg cgttcgtgaa gtatgggctg cgcaacctga
     1921 aagaaggggc gaagttccgt aaagggattg agaagctgtt aagcgaataa tgaaaatctg
     1981 accgaatgta atggttgata agaaaattat tacggcagtg aagattcgtg gcgaaagtaa
     2041 tttgttgcga attttcctgc cgttgtttta tataaacaat cagaataaca acgagttagc
     2101 aataggattt tagtcaaagt tttccaggat tttccttgtt tccagagcgg attggtaaga
     2161 caattagcgt ttgaattttt cgggtttagc gcgagtgggt aacgctcgtc acatcgtgga
     2221 catgtatgca gtgctctggt agctgtaaag ccaggggcgg tagcgtgcat taatacctct
     2281 attaatcaaa ctgagagccg cttatttcac agcatgctct gaagtaatat ggaataataa
     2341 agtgaagata cttgttactg gtggcgcagg atttattggt tctgctgtag ttcgtcacat
     2401 tataaataat acgcaggata gtgttgttaa tgtcgataaa ttaacgtacg ccggaaacct
     2461 agaatcactt gtagatgttt ctgattctga acgctatgtt tttgaacatg cggatatttg
     2521 cgatgctgct gcaatggcgc ggatttttgc tctgcatcag ccggatgcag tgatgcactt
     2581 ggctgctgaa agccatgtgg atcgttcaat tacaggccct gcggcattta ttgaaaccaa
     2641 tattgttggt acttatgtcc ttttggaagc ggctcgcaat tactggtctg ctcttgatgg
     2701 cgacaagaaa aatagcttcc gttttcatca tatttctact gacgaagttt atggcgatct
     2761 gcctcatcct gacgaagtaa ataataaaga agaattaccc ttatttactg agacaacagc
     2821 ttacgcacca agcagccctt attctgcatc aaaagcgtca agcgatcatt tagtccgcgc
     2881 gtggaaacgt acctatggtt taccgaccat tgtgactaat tgctctaaca attatggtcc
     2941 ttatcatttc ccggaaaaat tgattccatt ggttattctc aatgctctgg aaggtaaagc
     3001 attacctatt tatggtaaag gggatcaaat tcgcgactgg ctgtatgttg aagatcatgc
     3061 gcgtgcgtta tataccgtcg taaccgaagg taaagcgggt gaaacttata acattggtgg
     3121 acacaacgaa aagaaaaaca tcgatgtagt gctcactatt tgtgatttgt tggatgagat
     3181 tgtcccgaaa gagaaatctt accgcgagca aattacttat gttgccgatc gtccgggaca
     3241 cgatcgccgt tatgcgattg atgctgagaa gattggtcgc gaattgggat ggaaaccaca
     3301 ggaaacgttt gagagcggga ttcgtaaaac ggtggaatgg tatttggcta atgcaaaatg
     3361 ggttgataat gtgaaaagtg gtgcctatca atcgtggatt gaacagaact atgagggccg
     3421 ccagtaatga atatcctcct ttttggcaaa acagggcagg taggttggga actacagcgt
     3481 gctctggtac ctctgggtaa tttgattgct cttgatgttc actccactga ttactgtggt
     3541 gattttagta atcctgaagg tgtagctgaa accgtaagaa gcattcggcc tgatattatt
     3601 gtcaacgcag ccgctcacac cgcagtagac aaagcagaat cagaaccgaa ttttgcacaa
     3661 ttacttaacg cgacgagtgt cgaagcgatc gcgaaagcag ccaatgaagt cggcgcctgg
     3721 gttattcact actctactga ctacgtattt ccggggaccg gtgaaatacc atggctggag
     3781 acggatgcaa ccgcaccact aaatgtttac ggtgaaacca agttagccgg agaaaaagcg
     3841 ttacaggaat attgcgcgaa gcatcttatt ttccggacca gctgggtcta tgcaggaaaa
     3901 ggaaataact tcgccaaaac gatgttacgt ctggcaaaag agcttgaaga attagcggtt
     3961 attaacgatc agtttggtgc gccaacaggt gctgaactgc tggctgattg tacagcacat
     4021 gccattcgtg tcgcactgaa taaaccggat gtcgcaggct tgtaccattt ggtagccagt
     4081 ggtaccacaa cctggtacga ttatgctgcg ctggtttttg aagaggcgcg caaagcaggc
     4141 attccccttg cactcaacaa gctcaacgca gtaccaacaa ctgcctatcc tacaccagct
     4201 cgtcgtccat ataactctcg ccttaataca gaaaaatttc agcagaactt tgcgcttgtc
     4261 ttgcctgact ggcaggttgg cgtgaaacga atgcttaacg aattatttac gactacagca
     4321 atttaatagt ttttgcatct tgttcgtgat ggtggagcaa gatgaattaa aaggaatgat
     4381 gaaatgaaaa cgcgtaaagg tattatttta gcgggtggtt ctggtacacg tctttatcct
     4441 gtgactatgg ctgtcagtaa acagctatta cctatttatg ataaaccgat gatctattac
     4501 ccgctctcta cactgatgtt agcgggtatt cgtgatattc tgattattag tacgccacag
     4561 gatactcctc gttttcaaca actgttgggt gatggtagcc agtgggggct aaatcttcag
     4621 tacaaagtgc aaccgagtcc agatggtctt gcgcaggcat ttatcatcgg tgaagagttt
     4681 atcggtggtg atgattgtgc tttggttcta ggtgataaca tcttttacgg tcacgatctg
     4741 ccgaagttaa tggacgcagc tgttaacaaa gaaagtggtg caacggtatt tgcctatcac
     4801 gttaatgatc ctgaacgcta cggtgtcgtt gagtttgata aaaaaggtac ggcaattagc
     4861 ctggaagaaa aaccgttaca accaaaaagt aattatgcgg taaccgggct ttatttctat
     4921 gataacggcg ttgtggaaat ggcgaaaaac cttaagcctt ctgcccgtgg tgaactggaa
     4981 attaccgata ttaaccgtat ttatatggaa caggggcgtt tatccgttgc catgatggga
     5041 cgtggttatg catggctgga cacggggaca catcaaagtc ttattgaagc aagcaacttc
     5101 attacaacaa ttgaagagcg tcaggggctg aaagtttcct gcccggaaga aattgcttac
     5161 cgtaaagggt ttattgatgc agagcaggtg aagatattgg ccgagccgct aaagaaaaat
     5221 gcttatggtc agtatctgct aaaaatgatt aagggttatt aataaaatga acgtaattga
     5281 aactgaaatt cctgatgtgc taatttttga accaaaagta tttggtgatg agcgtggttt
     5341 cttttttgag agttttaacc agaaagtatt tgaagaagct gtagggcgga aggttaattt
     5401 cgtacaagat aatcactcga gatcggttaa aggtgtttta agaggactgc attttcaaat
     5461 aaaaccttat tctcaagcaa aattagtccg ctgtgttaaa ggtgaagttt atgatgttgc
     5521 tgtagatata cgaccagagt caagtacata ctgtaagtgg gtaggtgtct ttctttcagc
     5581 gcaaaataaa aaacaattat ggatacctga aggttttgca catggttttg ttgtagtaag
     5641 tgatgaggct gagtttttat ataaaacgac taattattat atgccaagtg ccgaaggttg
     5701 tatcagatgg gatgatccgg cattgaacat tgactggccg atgaaaacaa acgaacttat
     5761 cctatcggat aaagataaaa atgctgaaag atattatttt aagaaataag gaataaatat
     5821 gataccattt aacaagcctt atctccaggg aaatgaattg acatatattg cggaagcagt
     5881 gtctaatggc aaaatatcag gcgatgggat tttcactaag aaatgtcatg agttttttga
     5941 aaggaaatac ggatttaaga aagccttatt gaccacatct tgtacagacg ccttggagat
     6001 ggcagccatt cttttagata taaaacctgg cgatgaagtt atagctccgg cttacacctt
     6061 tgtttcaact gtcaatgctt ttgctctaag aggtgcaaaa ataatttttg ctgatagtta
     6121 tgatgataat ccaaatatgg atccagaatc tgcaagtaag ctcatcacaa ataaaacgaa
     6181 agcaataatt gttgtgcact atgccggtgt agcatgcgat atggataaat ttttagagct
     6241 ttcgaaagaa tataaaattc atatcattga agatgcagcg caagcaattg actcttatta
     6301 taaagataga ccattgggta gcattggtac gtttggaacc ttttcctttc atgaaactaa
     6361 aaatataatt tcaggagaag gagggttgat tgctttaaat aacgatgaat attttcatcg
     6421 ggcagaaatt attagagaaa aagggacgaa tagagcatct ttttttagag gggaagtcaa
     6481 taaatatgga tgggttgata taggatcttc gtttcttcca tctgatatga tagcagctta
     6541 tctttatgca caattggaga atgtagatgc tatacaaaat aagcgaaagg aattgtggag
     6601 agagtattat gacaatctaa aacagttggc caactctggg tatatacaac taccgataat
     6661 accagagtat gctaccaata atgctcatat gttttatatt gtatgcagtg accttaaaaa
     6721 acgctcagag cttatttctt atttaaaaga gagtggaata cattccgttt ttcattactt
     6781 atcattgaac aaaagtgagt attatttgaa gcaaaataaa aaaataagtt tgcaaaatag
     6841 tgataaattc gctgattgtc tgttaaggct gccaatgtat tatgaactgg agtgtaaaca
     6901 agttaactat atttctgaaa aaatagctca tttctttaaa aaacacgcat aaaaatattg
     6961 tggtggtatt ataaccgcca cgttatgttg ctggagaagt tctatactat gaaatatggt
     7021 ttatgaatag agaatataag cttttaattt acatatatag tgtgagaata tacacggcat
     7081 tagtgacgat ctttttaatt ccaatattaa ttggagaaat tgggttagag gcgtacggtt
     7141 tgattggctt ttttgcagtg cttcaggctt gccttagtat tttagatgca gggttggggg
     7201 gggtaataac aagagaagca atagtatcaa ggaaaaatca aggaacatat aaaaaattta
     7261 gtattttgta taagaaaata attatatttt ttataattgt atcattgtta ttagttactt
     7321 gtggttggtg ggtaagtgaa caatatagta cttcatggct aaatacaaag cttgataaaa
     7381 gtgtggttgt tttttgtaca acagtaatgt tttgggtatt cgcattacgc tatatgcaag
     7441 gaccgttccg tagcatatta ctttcaaatg aatcgcaaat catattgaca actattaatc
     7501 tatttaccat cacactatct cagccattga ctatattttt aatgaagtac ctagatgagg
     7561 gaattaagtt ttattttttg atgcaactta tttcatcagc tattggctgt atttctatgg
     7621 tgttatatag tgaaaaaata aggaggaaag tattattttt atgtcctctc gaagaggata
     7681 gcataaaatc tgaagatact tctgtcagaa aattaatagt tttcgcatta caattatcaa
     7741 cactttctat tttatgggtt ttagttaacc agtcagacaa attagcacta acaaaataca
     7801 gcacattaac ggaatatggt atttatagtg ttgcagtatc tatcataagt gtgttagcta
     7861 tattgagtga tccgttgaat cagtatttac aacctagatt aacaagatat tatcatcaaa
     7921 ataacttaaa ggaatactca aaattattta gtggtgcatt aaagtttata tgtatattaa
     7981 caatacctct aagtgtattt ttattttttt atggtaagga tgtgttattt atatggagcg
     8041 gtgatgaaac attatcaata aaagctgcga agtatttacc ctggttattt ataggtgggg
     8101 tgttttcaat atactctaat tttgtatttt tgttattata tagttttggt gagttaaaaa
     8161 gacacacaat agtgtatgcg ttatttagtc ttttcgtaat tccggcaaat gttttcctag
     8221 caaaacaata tttaggtcaa gggacatcta ttttctttgg tattagttct atgttcttat
     8281 ttctcttatg gggggggtat aactttgcaa aatttttcgt caagggattg cgtgttatat
     8341 atgtatatat cattcctttg tttctggttg aaataatata tttcaaaact tcaacagctt
     8401 ttccgtataa tcatactgta aagtggactt tattcattca attattttcg gttggcttgg
     8461 tcgggcttgc tttagctatt atttactgca agctggtaga taaaaaaaat tcacaagtga
     8521 tattaaagat tgttgacaaa tgaatatata tatttatgca agctcatatg atgaaaatag
     8581 tggtggctct gtagtcctac ataggctatg ccatataata aataaacaca gttcccatag
     8641 tgcatattta gttaaattag atccatttca ttatggtaaa aaaacaatta gaaaatacct
     8701 gtcaaaatta aaatgggaac tttgtaataa gtttaaattt aaaactaatg acgattggga
     8761 tactcctgtt tggcacaaat taaacaatat cccttcaaat tccgtggtga tttatccgga
     8821 aataattaat ggcaatcctt taaaaataaa aaatgttgta agatggttat tacatcagcc
     8881 cggtcatcat actaatgtca ttgattatgg gaaaaacgaa ctgtatttta aatttaactc
     8941 ggcgattcat gactttgaaa atgatggatc ttatacagca gcaaatgagc taaaggtaat
     9001 ttactatcca gttcaaatat ataatgaaaa gttaaatcaa gaaagggata tagagtgttg
     9061 ttatcttgta cggaagggat tttataaaaa aagcgtccat ccccctaaag caataaaaat
     9121 tgacggatta actcatcaag aaatagctga tgtttttaga cgctcacaga aatttatttc
     9181 atatgatgat tatacggcat attctatatt ttctgttctg tgtggttgtc catcttatgt
     9241 agtaccgaca gaagggcaaa ctgttaatga ttggtatcct gatgaaagag atcgttatgg
     9301 gatatcatat ggttttactg atgagcaagc taaatgggca gaagagacca aagatagagt
     9361 ttataggcat ataataaatg agcataacaa atcaatagat agggtgatta attgtttaca
     9421 agaaattgaa gttttttttg gtaaaaattg aactactaaa cagttggtaa aacattattc
     9481 attttatgac aattgagtgt tttttagaaa agtaacattt aaatgagtta atgttgtatt
     9541 ttattagtag tatgcaaata aaataggtaa aacatgatag aacaagataa atgtatcatt
     9601 gcagtcgtgg tccttttcag acctgaaatt gcacgcatac atggattgct gaaaagtata
     9661 attatgcaag ttgacaaggt tgttcttatc gacaatacag acaagtctaa cttaataata
     9721 cctgattccg agtttgagtc atacggagaa aaaattgaac attatcgact gaacaacaat
     9781 ctaggcattg caaaagctca gaatattgga attcattatg ccgaaaaatc gaaagcatct
     9841 catattttat ttttggatca agacagtatc gtctcagaag gaatggttaa aacattgcta
     9901 atcaatgagc gtgagctttt aaatagtgga aaaaaagtcg ctgttttagg tccagcattt
     9961 aaggatgaga aaactggaaa ggtaacaggt gcaattcaca ttagcccatt ttataaaacc
    10021 aagctgtgtc atggtgttca tccgctagaa acagattttc taatttcttc aggaagcttg
    10081 gttaggatgg aggtgttgca aaaaatcgga tttatggatg aggagttgtt tatagatttc
    10141 gttgacattg aatggtgcga acgcgcgaag aaaatgggat tgcgatctta tgttgtgcct
    10201 gatattgtca tgatgcacaa tattggaaat gaagcaaaac gaatattggg taaaaatgta
    10261 ataatgcata gtgattttag acattatttc atagtaagga attcaattta tttgattctt
    10321 aaagataagc tttcattcaa tcattgtgta tatttattca tccggttgcc attatttata
    10381 gctgttcgca ctcttaattc atcttcgaag ttaaaaaaaa ttaaactgtt agcaactgca
    10441 ataaaagatg gtgttgtgga taagatggga aaaggttact tctctaattc ttgataaatg
    10501 tattggcaat gtaaactaaa cattaataat ggccacttaa cctaatcatg aaatgagatt
    10561 gtaatgtttt tatacctctc aatatttata tgcatttcta ttctatcttt ttttccttac
    10621 cagaaatatt tgttaaaagc aataatgatc tttttgcttt tgatgtgtgc cttccgtagc
    10681 gagtttgtcg atagggatta tacaaactat attacgctaa tttttgagtc agcaaataac
    10741 ttattctatc caatagaaat atcatttaaa gtaataagtt ttattgctgt taatatgctt
    10801 ggcggatatt attttgtttt tattattttt gcgctaatat ctatctactt aaaatacaat
    10861 ataataaaaa aatcctcacc gtttttactg ctatctgtac ttgtgtatta ctcaaataca
    10921 tttttactgc aagatatgac tcagatccgg gctggagttg caggtgctat agtactatat
    10981 tcagtgttac aatatgcaaa aaataaaaat ataatgagtt ttgtgatgtt gattttcctc
    11041 gcatctacat ttcatataac tacgttgtta ttttttattg ttcttgcatt cgatactaat
    11101 gtagttagtc gaagatatat ctttatttat ttcttgacct tatttggggc atgttgttgt
    11161 tattatgcag gtgtcaattt cttaacctta ttaagatata tccctgtttc ttatgtacaa
    11221 tataaattta gtgactatat tagtcaaagt caaggtgctg attttgttcc tgtcaatatt
    11281 ttctctgtaa cgcaattatt gcatttgctt atagttatat tatcttttat tttttctcga
    11341 aaaaaaatct tatctcgtga taaggtgctt gtcattaaaa tttattcatt atctccgctt
    11401 gctttcatca tattatcttc tatgccagta ttcgctttac gtgttagtga actttttgct
    11461 attagtgaaa taattctact tccattcctg ccccttcttt ttagacaaaa acagtttgct
    11521 aaattagcga ttataggaat atgttttatt atgttttata ttaatatata tcatcttgag
    11581 attttaaatg agtattcggc attgtaagct aagaatatgt tatatatgat tatggctatt
    11641 gtttggcacc attgatgaat acaaatcaaa atcagtgtta ataatgagga aaaaaatgaa
    11701 attaaaaagc atggctgttt tattatcgag ttacaatggg gaaaaatata ttggagagca
    11761 attggactca ataataaaat gctatagaga tttcgattta catattcata taagagatga
    11821 tggttcagtt gattcaacat gtgaaattat taaagagtat atatcaaaaa atgattctat
    11881 atttttatat gaaggtgata acgttggcgt catagctagt tttttgtggt tggttgagaa
    11941 tgttggtgat tatgactatt acgctttttg cgatcaggat gatgtatggg aacctcttaa
    12001 attgattgca gctacaacta agattattaa gtataatcaa gatatagcaa tagggtattg
    12061 ctcctcatat aactatgtgg acaaagagtt aaatcatatc ggccgttata attctcagag
    12121 tgatttttct ttaaacaata ttttaattga aaattgtgcg ccaggctgta ctttcgtgtt
    12181 taatcaatct ttacgtaaat tatacttgga cataaatgaa gccaatatgg ccaatcgtat
    12241 tgtcatgcat gattggtttt ttttaatact ggcaagaaca tttggccacc taatatatga
    12301 tcataatagc tacctaagtt ataggcagca tgataataat gtcgtaggta taaagtctgg
    12361 ttttaagaat attctatgta atagattaaa acagttcaaa aaatataagc aaaatgggag
    12421 gcatcttcta tcgcttcaga tcgatttggt ctccttatat tgtttaaagc ataataaaga
    12481 agcagcatat gaaataagtc atgggtttgt agagtctcaa gcaagcttgg taaaaagatt
    12541 gaggtatgtt ttttccgggt atgtaaaaag agttaggttt attgatgatg tgctttttaa
    12601 agttttgttt attattggat ggtataagta aggataaaag atgcctcgta aaaaaatttt
    12661 gcttgtcgca aatacactct ggtcggtata caatttccga aaaggattaa taaaaagttt
    12721 aattgaaaaa ggatacgatg taaccattgt tgctccagaa gatgaccatt tggaaaaaat
    12781 tgtcgattta gggtgtaaat ttgaatcaat ttctgtttcc tcgcaaggca aaaacccact
    12841 taaagattta atgctattat ttaagctaat aaaaatatat aagaaaataa aacctgattt
    12901 tatttttcat tacacaataa agctaaatat ttatggatct atagccgctg gtattacgaa
    12961 ttgtaaatct atagcggtaa ccacagggtt aggatttgta tttaataaag aaacacttct
    13021 gactaaattc ataactcagt tgtatgcttt ttcttttcgc tttgcaaaag aggtttggtt
    13081 tctgaatgag gatgatagaa atgtatttct gagaaaaaga ataatcaatg agagtaaatc
    13141 atttattctg gcaagtgagg gtgttgatac cagttatttc acccccagcc aggtttcgtg
    13201 caagactaaa tataatgata atgttacatt tcttcttata gctcggatgc tatgggaaaa
    13261 gggaattggt gtatatattg atgctgctaa tattctaaag tctgagtttc ctggcattag
    13321 attccagcta ctgggtgctt gcgatagcca aaaccccgga gcgattacaa gacaggaaat
    13381 tgaaaactgg caaattaaag ggattatcga gtatttaggt gttgaaagtg atgttagacc
    13441 gcacataatt agcgcagatt gtattgtttt gccttcattc tatagagagg gggtacctcg
    13501 cgtgttgatg gaagcttcat caatgtgtaa gccaataatt actacaaaca atgtaggttg
    13561 caaggatgtt gtagtcgatg gtgaaacggg atacctatgc aatgtacgtg attacattgg
    13621 gttagcaaat gtaatgcgta aatttattga actcacccca caagaaagag aaactatggg
    13681 caaaaaaggg cgggactata tcattaaaaa ttttgatgaa aggaaaataa taaaaatata
    13741 ccatgataca ttaacaaaat atatatctta aattgtgttg aaagttttat ttaacaaatc
    13801 tactagattg aagtgtatcc ttgagctgtt ggatatgtgt taaattttat tttttaaaaa
    13861 tttacctcat gtcatgtgta tctatagctt aaaaaggtgt acttttggtt aaagtgaaaa
    13921 tttttatgct atcataatta tttgaactcg cagtggaaat tcagctcagt agtttagact
    13981 aaaaatattt tgattatgat tttaatataa aagagaataa aaatgtcatt cttatcagat
    14041 tcggaactca gaaaaatagg ttttaaaaaa cttggaaaaa atgtcaaaat aagtgaaaaa
    14101 gcgtcaattt ataaccctga aaaaattgag attggggata attctcgaat agatgatttt
    14161 tgtctattgt ctggaaaaat ctccatagga aataatgttc atattgccgc atactgtaat
    14221 attgctgggg gaatagaagg catcacattt gatgacttct ctgggttggc atatggttgt
    14281 catgtctttt ctcagtctga tgattatact ggacgtactc tgaccaaccc aacgattcct
    14341 aaaaaatata aaaaagaaat aattaagaaa gttataattg gtaaacatgt aattgttggt
    14401 acaaattcat tagtttttcc cggcgtaaca attgaagaag gatgctcaat cggagctatg
    14461 acaatggtta caaagtctac aaaagcttgg gggtgttatt tcgggattcc tgcaaagaga
    14521 ataaaggaaa gaaaaaaaga tctgctggag cttgaacaac tctttcataa agaaaataaa
    14581 tgaaagcagt tagctgctct gttcaatatt taagattttt ctgtttagtt attggttccg
    14641 aaaagagtac gtaatgctgt ttcttgtact tgggagccag gaaagatcat caagcgtaca
    14701 cttgttacac taaataattc gcattttatg ttcaataatt gatatgttcc ttattaccta
    14761 aaactattct tcatagttta tatatgatca aatactcctt gcctaaataa ggagaacaaa
    14821 atgggacttg aaaatttgat ggaacatatt tctactatcc ccgattactg acaatcttgg
    14881 aaagtagaac ataaattgtc agatattcta ctgttgacta tttgtgccat catttctggg
    14941 cagaaggttg ggaagatata gaggacaggg aaagatcatc ggaagtacac tttttgtact
    15001 aaataattcg cattttatgt tcaataattg agatattcct cattacctaa agctgttttt
    15061 cattgcttat acatgatcaa atactcctta cataattaag gagaacaaaa tggaacttaa
    15121 aaaattgatg gaacgtattt ctgttatccc cgattacaga caagcctgga aagtggaaca
    15181 taaattgtcg gatattctac tgttgactat tggtgccgtt atttctggtg cagaaggttg
    15241 ggaagatata gaggattttg gggaaactca tctcgatttt ttaaaacaat atggtgattt
    15301 tgaaaatggt attcctgttc acgataccat tgccagagtt gtatcctgta tcagccctgc
    15361 aaagtttcat gagtgcttta ttaactggat gcgtgattgt cattcttcag atgataaaga
    15421 cgtcattgca attgatggaa aaacgctccg gcactcttat gacaagagtc gccgcagggg
    15481 agcgattcat gtcattagtg cgttctcaac aatgcacagt ctgatcatcg gacagatcaa
    15541 gacggatgag aaatctaatg agattacagc tatcccagaa cttcttaaca tgctggatat
    15601 taaaggaaaa atcatcacaa ctgatgcgat gggttgccag aaagatattg cagagaagat
    15661 acaaaaacag ggaggtgatt atttattcgc ggtaaaagga aaccaggggc ggctaaataa
    15721 agcctttgag gaaaaatttc cgctgaaaga attaaataat ccagagcatg acagttacgc
    15781 aatcagtgaa aagagtcacg gcagagaaga aatccgtctt catattgttt gcgatgtccc
    15841 tgatgaactt attgatttca cgtttgaatg gaaaggtctg aagaaattat gcgtggcagt
    15901 ctcctttcgg tcaataatag cagaacaaaa gaaagagccc gaaatgacgg tcagatatta
    15961 tatcagttct gctgatttaa ccgcagagaa gttcgccaca gcaatccgaa accactggca
    16021 cgtggagaat aagctgcact ggcgtctgga cgtggtaatg aatgaagacg actgcaaaat
    16081 aagaagagga aacgccgcag aattattttc agggatacgg cacatcgcta ttaatatttt
    16141 aacgaatgat aaggtattca aggcagggtt aagacgtaag atgcgaaaag cagccatgga
    16201 cagaaactat ctcgcgtcag tccttgcggg gagcgggctt tcgtaatctt gccctggaga
    16261 tagcgctgat gtccggcggt gcttttgccg ttacgcacca ccccgtcagt agctgaacag
    16321 gagggacagc tgatagaaac agaagccact ggagcacctc aaaaacacca tcatacacta
    16381 aatcagtaag ttggcagcat cacccgttct caggaaaata aaaaagaaca cttctttatt
    16441 ggtgtctatc catctggtac tcatcatggt caagatagtc caaatgaaaa atattttgat
    16501 ggtaagaacc cgctctacaa taaattctat aactatgatt ttcagttagg gaaatttgtt
    16561 gacttctttc ggcgtagttc attttacaat aatacattat taataataac gtcagatcat
    16621 tcaacatttc cttcgacaga atataaaaaa gcatttaata gcgattctcg ttactttgta
    16681 ggcgaaatac catttctggt tattggagga gatatcactc ctgaaacttt ggatgcagac
    16741 ggtaaaaatt cattaagctt tgcgccaaca atattgcaca tgttagggat tcagtattca
    16801 atgaactatt ttttgggatg ttctcttttt gataaggaat gcacatcgcc attttcacat
    16861 ttttctgcta ttggtagtga ctatttcatt acaagcaaag aaaatcatgt tgaactaata
    16921 ccaaataata gtgatagtga attaataaaa cttgctgaac gtttttataa tattagtgga
    16981 taagtagatg attgggtaaa aagcaatcga tccactaatt atgaaaaata tggctgtaaa
    17041 ataagatata aattaagcta ttctttatct taaataagcc gcaaccccgc ggtgaccacc
    17101 cctgacagga gtaaacaatg tcaaagcaac agatcggcgt agtcggtatg gcagtgatgg
    17161 ggcgcaacct tgcgctcaac atcgaaagcc gtggttatac cgtctctatt ttcaaccgtt
    17221 cccgtgagaa gacggaagag gtgattgccg aaaatccagg caagaaactg gttccttact
    17281 atacggtgaa agagtttgtt gaatctctgg aaacgcctcg tcgcatcctg ttaatggtga
    17341 aagcaggtgc aggcacggat gctgctattg attctctcaa gccatacctc gataaaggtg
    17401 acatcatcat tgatggtggt aacaccttct tccaggacac cattcgtcgt aaccgtgagc
    17461 tttctgccga aggttttaac ttcatcggta ccggtgtttc cggcggtgaa gagggggcgc
    17521 tgaaagggcc ttccatcatg cctggtgggc agaaagaagc ctatgaactg gttgctccga
    17581 tcctgaccaa aatcgccgcc gttgctgaag atggcgaacc gtgcgttacc tatattggtg
    17641 ccgatggcgc gggtcactat gtgaagatgg ttcacaacgg tattgaatac ggtgatatgc
    17701 aactgattgc tgaagcctat tctctcctga aaggcggcct gaatctctct aacgaagaac
    17761 tggcgcagac ctttaccgag tggaataacg gtgaactgag cagctacctg attgacatca
    17821 ccaaagacat cttcactaaa aaagatgaag acggtaacta cctggttgat gtgatcctgg
    17881 atgaagcagc aaacaaaggt accggtaaat ggactagcca gagcgcactg gatctcggcg
    17941 aaccgctgtc gctgattacc gagtctgtgt ttgcacgtta tatctcttct ctgaaagatc
    18001 agcgtgttgc cgcgtctaaa gttctctctg gtccgcaagc gcagccagca ggcgacaaag
    18061 ctgaattcat tgaaaaagtt cgccgtgcgc tgtatctggg caaaatcgtt tcttacgctc
    18121 agggcttctc tcagctacgc gccgcgtctg aagagtacaa ctgggatctg aactacggcg
    18181 aaatcgcgaa gattttccgt gctggctgca tcatccgtgc gcagttcctg cagaaaatca
    18241 ccgatgcata tgccgaaaat ccgcagatcg ctaacctact gctggctccg tacttcaagc
    18301 aaattgccga tgactaccag caggcgctgc gtgatgtcgt tgcttatgca gtgcagaacg
    18361 gtatcccggt tccgaccttc gccgctgcgg ttgcctatta cgatagctac cgtgccgctg
    18421 ttctgcctgc gaacctgatc caggcacagc gtgactattt cggtgcacat acttataagc
    18481 gcattgataa agccggtgtg ttccatactg aatggctgga ttaatctgat ttaaccaaca
    18541 ataaaattga ggcccggcgt atattgcacc gggctttttt ttgccaatta tcttatagac
    18601 taaatttcac tgcttaatat taacttaata aatatcagct attcttataa agaaaatctg
    18661 aattgttttt cgttgcgttg accatcgaac aacgtagcgt taaaactttt agctcttatc
    18721 aggatgctaa aaacatcatg attcacagtt aagttaattc tgagagcatg aaatgaaaat
    18781 caccatttcc ggtactggct atgtaggctt gtcaaacggg cttctaatcg cacaaaatca
    18841 tgaggttgtg gcattagata ttttaccgtc acgcgttgct atgctgaatg atcggatatc
    18901 tcctattgtt gataaggaaa ttcagcagtt tttgcaagca gataaaatac actttaatgc
    18961 cacattagat aaaaatgaag cctaccggga tgctgattat gtcatcatcg ccactccaac
    19021 cgactatgat cctaaaacta attatttcaa tacatccagt gtagaatcag taattaaaga
    19081 cgtagttgaa ataaatcctt atgcggttat ggtcgtcaaa tcaacggttc ccgttggttt
    19141 taccgcagcg atgcataaga aatatcgtac tgaaaatatt attttctctc cggaatttct
    19201 ccgtgaaggt aaagcccttt acgataatct ccatccgtca cgtattgtca taggtgagcg
    19261 ttcagaacgc gcagaacgtt ttgctgcgtt gttacaggaa ggagcgatta agcaaaatat
    19321 cccgaccctg tttaccgatt caaccgaagc agaagcgatt aaacttttcg ctaatactta
    19381 tctggcgatg cgcgtagcat actttaatga actggatagc tatgcagaaa gtttagggct
    19441 gaatactcgc cagattatcg aaggcgtttg tctcgatccg cgtattggca accattacaa
    19501 caacccgtcg tttggttatg gtggttattg tctgccgaaa gataccaagc agttactggc
    19561 gaactaccag tctgtgccga ataacctgat ctcggcaatt gtcgatgcaa accgcacgcg
    19621 taaagatttt attgccgatg ccattttgtc acgaaagccg caagtggtgg gtatttatcg
    19681 tctgattatg aagagcgggt cagataactt ccgtgcgtct tccattcagg ggattatgaa
    19741 gcgtatcaag gcgaaaggcg ttgaagtgat catatacgag ccagtgatga aagaagactc
    19801 attcttcaac tctcgcctgg aacgagatct cgccaccttc aaacaacaag ccgacgtcat
    19861 tatttccaac cgtatggcag aagagcttaa ggatgtggca gacaaagtct acacccgcga
    19921 tctctttggc agtgactaac atcctgttat cagggcgatt ttcgccctga ttctcttatg
    19981 ttccctttgt aataattcat tatttttatc atttatccta tagcattcat ggcgattatc
    20041 gctaaactat ggcgacttaa aattatttcg tccgttaggg taatgatgag agtagaaaat
    20101 aataatgttt ctgggcaaaa ccatgacccg gaacagattg atttgattga tttactggtg
    20161 cagttgtggc gcggcaagat gacaattatc atctctgtca ttgttgctat tgccctggct
    20221 atagggtatc tggccgttgc caaagaaaag tggacttcca cagctatcgt tactcaacct
    20281 gatgtggggc aaatcgctgg ttataccaac gcgatgaatg tgatctacgg atcggctgta
    20341 ccgaaagtct ccgacattca ggcttcgctt atcggacgtt acagcactgc attctcagca
    20401 ttagcggaaa cgctggataa ccaggaagaa gcagagaagc tgaccattga gcctaccgtt
    20461 aaaaaccagt cgttaccatt ggcggtgtct tatgttggtg aaacacctga aggtgcgcag
    20521 aagcagctgg cgaagtatat ccagcaagtt gacgaacagg tatatgaaga gctggaacaa
    20581 gacctgaaag acaacatcgc gctgcgtacg aaaaacttgc aggattctct gaaaacccag
    20641 gaagtagtcg cgcaggagca gaaagatctg cgtatccgtc agattcagga agcgttgcag
    20701 tatgcgaatc aggcgcaggt gacaaagcca cagattcagc agacacagga cgtaacccag
    20761 gatactatgt tccttttggg gagcgaagcg ctggagtcga tgattaagca cgaggcgact
    20821 cgtccgttgg tgttctcatc aaactactat cagactcgtc aaaacctgct ggatatcgac
    20881 aatcttgacg ttgataaact tgatattcat gcttaccgct atgtaatgaa accgacgtta
    20941 cctattcgtc gcgatagccc gaaaaaggca attaccttga ttctggcggt actgctgggc
    21001 ggcatggttg gcgcggggat tgtgctgggg cgtaacgctc tgcgtaatta caacgcgaag
    21061 taatctttcc ggttttaagg aaaaagggca gggtggtgac accttgcccg tttttttttg
    21121 ccggatgcga caacaacatc gcatccgctt accc
//
