LOCUS       AB812060               20161 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli genes for O-antigen biosynthetic locus, partial
            sequence, strain: CDC149-51.
ACCESSION   AB812060
VERSION     AB812060.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 20161)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..20161
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="CDC149-51"
                     /db_xref="taxon:562"
                     /note="serogroup:O140"
     gene            <1..904
                     /gene="wcaM"
     CDS             <1..904
                     /gene="wcaM"
                     /codon_start=2
                     /transl_table=11
                     /product="colanic acid biosynthesis protein"
                     /protein_id="BAQ01705.1"
                     /translation="YAILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDRDILIS
                     DHIIERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVEN
                     GKHFVIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIK
                     GKYLSIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKP
                     QHLFMRNIKVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNERGQSSV
                     DIDRINHHIVNVEKINFRLPERRE"
     gene            1062..2057
                     /gene="gne"
     CDS             1062..2057
                     /gene="gnu"
                     /note="O140_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4-epimerase"
                     /protein_id="BAQ01706.1"
                     /translation="MNDNVLLIGASGFVGTRLLETAIADFNIKNLDKQQSHFYPEITQ
                     IGDVRDQQALDQALAGFDTVVLLAAEHRDDVSPTSLYYDVNVQGTRNVLAAMEKNGVK
                     NIIFTSSVAVYGLNKHNPDENHPHDPFNHYGKSKWQAEEVLREWYNKAPTERSLTIIR
                     PTVIFGERNRGNVYNLLKQIAGGKFMMVGAGTNYKSMAYVGNIVEFIKYKLKNVAAGY
                     EVYNYVDKPDLNMNQLVAEVEQSLNKKIPSMHLPYPLGMLGGYCFDILSKITGKKYAV
                     SSVRVKKFCATTQFDATKVHSSGFVAPYTLSQGLDRTLQYEFVHAKKDDITFVSE"
     gene            2300..3193
                     /gene="galF"
     CDS             2300..3193
                     /gene="galF"
                     /note="O140_02"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ01707.1"
                     /translation="MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNV
                     RQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRS
                     QVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLS
                     ADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFRKGIEKLLSE"
     gene            3449..4762
                     /gene="wzx"
     CDS             3449..4762
                     /gene="wzx"
                     /note="O140_03"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAQ01708.1"
                     /translation="MQCSGSCKARGGSVDNFIYGEALAFNTNLNKNIAYLFLVQGSSY
                     LLPLITFPYLVRVLGPEFFGVLGFCQASMQYLVMLTEYGFNWTATQKIAINKNDRNKL
                     THIFWGVIFAKILLSFFAFIMLTLVCIFIERYRDVALILAAFSPLVFGNIIYPIWFFQ
                     GLEKMKWISLCTITARAMLIPLTFIFVKSPEDVWIAALIQGAINLFAGCISLYIIKRN
                     KWVGRVVFSVKDIKENLVDGWHVFVSTSAISLYTTSTTIILGFVSGPIAVGYFNAANT
                     IRNAAQGLLNPLTQAIYPRINSLFDTNYPQALSLIKKSLRYIGLLSLLGSSFLFILAP
                     YIISLTVGEKYLYSVDILRWMAFLPFVLVLSNIFGVQTMLTHDYKKEFSYILILSGVL
                     NLTIIFPLVYKYSAIGAAISILITESFVALAMYLFLRIKNIYIIK"
     gene            4759..5868
                     /gene="glf"
     CDS             4759..5868
                     /gene="glf"
                     /note="O140_04"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="BAQ01709.1"
                     /translation="MSGESMYDFIIVGAGLFGAVCANELSKKNKKVLVLEKRNHIAGN
                     AYTENDEGIQVHKYGAHIFHTNDKEVWEYVNLYAEFNRFTNSPLAFSGGKLFNLPFNM
                     NTFYQLWGAQTPQEAMSIIDEQRREIGEKIPTNLEEKAISLVGRDLYEKLIKGYTEKQ
                     WGRKASELPAFIINRIPVRMTFDNNYFTDRFQGIPVGGYTKMVERMLDGIEVRLNTDY
                     LKNKSNFRKMGTVVIYTGPIDEYFEYCYGMLEYRSLRFETSTLPVSNYQGNAVINYSE
                     RKVPYTRIIEHKHFDPVDTPITKITKEYPCEWKEGDEPYYPINDEKNMLLFNKYKKLS
                     KNEDEVYFGGRLAEYKYYDMHQVIRAALNLSRKWS"
     CDS             5872..6864
                     /note="O140_05"
                     /gene="wccA"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01710.1"
                     /translation="MKYTSVHVCCPGNIISGGPELLHQFVHELRQNGVDAHIIYFPFE
                     QLYDTPALYSHYDIAKSNINEIKKEDIVFIPETATYLINRISCENIAIWWLSIDFYYG
                     CPVDKKISPLMLKHYVDVWKGKKLSFSEMKKFQHFHQSYYAKDFLSRKGIISKELSDY
                     LNDEFIKTNILNRDNNRKKIIAYNPKKGIKTTNRLIKAFPNYKFVPLINMRPNEIKNL
                     LKSIMIYIDFGHHPGKDRFPREAAISGCCIITGQRGSAKNNVDLPIPDRFKLRDNSND
                     LEVKFGELVESIFDCFEKETMSFEDYRTKIRQEHQIFQRNVYEIAKSCAITKEI"
     gene            6909..7994
                     /gene="rmlB"
     CDS             6909..7994
                     /gene="rmlB"
                     /note="O140_06"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6 dehydratase"
                     /protein_id="BAQ01711.1"
                     /translation="MKIIVTGGGGFIGTALIHYIIYNTQDSVVNVDKLTYAGNLESLA
                     DVSDSERYVFEHADICDAAAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSALDGNKKNSFRFHHISTDEVYGDLPHPDEVNNKEGLPLFTETTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLIILNALEG
                     KTLPIYGKGDQIRDWLYVEDHARALYTVVTEGKAGETYNIGGHNEKKNIDVVLTICDL
                     LDEIVPKEKSYREQITYVADRPGHDRRYAIDAEKIGRELGWKPQETFESGIRKTVEWY
                     LSNTKWVDNVKSGAYQSWIEQNYEGRQ"
     gene            7994..8893
                     /gene="rmlD"
     CDS             7994..8893
                     /gene="rmlD"
                     /note="O140_07"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAQ01712.1"
                     /translation="MNILLFGKTGQVGWELQRSLAPLGNLIALDIHSTDYCGDFSNPE
                     GVAETVRSIRPDIIVNAAAHTAVDKAESEPEFAQLLNATSVEAIAKAANEVGAWVIHY
                     STDYVFPGTSEIPWQETDATAPLNVYGVTKLAGEKALQEHCAKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKEREELAVINDQFGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAS
                     GTTTWHDYAALVFEEARKAGIPLALNKLNAVPTSAYPTPARRPHNSRLNTEKFQQNFA
                     LVLPDWQVGVKRMLNELFTTTAI"
     gene            8951..9826
                     /gene="rmlA"
     CDS             8951..9826
                     /gene="rmlA"
                     /note="O140_08"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="BAQ01713.1"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGG
                     DDCALVLGDNIFYGHDLPKLMDVAVNKEGGATVFAYHVNDPERYGVVEFDKNGTAISL
                     EEKPLQPKSNYAVTGLYFYDNDVVEMAKNLKPSARGELEITDINRIYMEQGGLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAFRKGFIDAEQVKVLAEPL
                     KKNAYGQYLLKMIKG"
     gene            9834..10367
                     /gene="rmlC"
     CDS             9834..10367
                     /gene="rmlC"
                     /note="O140_09"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="BAQ01714.1"
                     /translation="MNVIRTEIPDVLIFEPKVFGDERGFFFESFNQKIFEEAVGRKVE
                     FVQDNHSKSSKGVLRGLHYQLEPYAQGKLVRCVVGEVFDVAVDIRKSSPTFGKWVGVN
                     LSAENKRQLWIPEGFAHGFLVLSEVAHFVYKTTAYYSPKFERGICWKDPFLSIEWPEI
                     GEVLMSFKDKELPSLII"
     CDS             10434..11402
                     /note="O140_10"
                     /gene="wccB"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01715.1"
                     /translation="MNIIIRSDFFLAKLLLNNLPPKYIIYGVEELIDINEKLNRTFLH
                     KLIKYRLIPVFKLTLCNLLRSCFKKRNKDKVFYFDIDRIDILASLILRNWDADKQIIW
                     LWNPTAKVMKSTTQLLFFINLIKKNKVEIWTFDQNDASLYGLKYYNQIYSLAMVDLFK
                     QTNNSIDVLFVGQDKERLQLLLMIKQKMDREKLVTYFHVVKDGGVTYTRDEKAFLSDE
                     ILSYEDYIHKVQQAKCLLDINQSGQTGLTLRVLEALFFNKKLITNNPNVVKYNFYNSN
                     NIMIIEDKVDNVSFNEFINSSYQEIEQSIKNEYDVEFMLDTIFQTS"
     gene            11425..12615
                     /gene="wzy"
     CDS             11425..12615
                     /gene="wzy"
                     /note="O140_11"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAQ01716.1"
                     /translation="MHRNITLKLILACLTTFVMMLFFPLWLNLLIFTIILFISDNSLK
                     IPVSVILALLSSLFISSVDIAYDLKNYHDLFVNINSDIYTSEFKFEPFLLYYYSVLSQ
                     LDVDFRVVLFLQSLFLNVTLLYVFIKTLGIKGIKYYGLLLIFPQYVQLSLFLSRQTIS
                     LLFVVLLITYCLNNKMTLFKFIVVSTIAVSAHAISLLYITIILLSSRLKKYLTWKMLF
                     TIWLVGILMPITADIMNNILQNVFNQIPLLDRKIGFYMNSVSTNISASLTLYSISILP
                     LHILFFMILLSIKKKKYKTTATAFTFVYLIVYYLIIFLINYPLLPARIGLLIIIFTPY
                     FYFVAINVFYSDSKYYKVMENFGVLFVLAIFIRFLFTNDYGDYNVNLANKHILEYSLS
                     NLLN"
     CDS             12626..13402
                     /note="O140_12"
                     /gene="wccC"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAQ01717.1"
                     /translation="MKYIVGSGWWCNEKEDYREKCYGDNSIRGKEFHQKWYESLLLNT
                     SPAEIYIVDSDSPIKPNFDKRIKFVSLNENGGHSTNLTGKYSGWMRSVIHSMSYAQCC
                     DCDYYIYVEQDVLLKGKGIVEYCISKMTKPFMFGLCHDHHNPLQQSFFIIKKDYIDIF
                     LSRLYLIKYNDFDISPEKKFALATSPFFHLIPQILFVRPKSKLMLRLFWRIQNTLAKI
                     LGSYDYLPIGYGRDRPINLSDKYYYFQHGTMEEINDYYIQ"
     CDS             13383..14249
                     /note="O140_13"
                     /gene="wfeH"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01718.1"
                     /translation="MTIIFNKIIFLLKCLFSTIKLHLRAIFCRLNRNQCVSQNSEYII
                     TLTSYHERFNTLYLTLESLFNQSVKPSNIYLWISQEDIDKYGGLPDSLPRYINAGLTV
                     KILKENIRSYKKLSYIEDVLKKDNNIKFIITADDDIMYPRRWAQGLIQTTKKHGSVSC
                     YRGHNLTYAEGSYNYNQSINQNKFSVEPSFDLLPTGCSGICYLRKSINKLVNDRRFLN
                     FAYDADDIWYKAMTLSAGFKCVRVEPRNIHFPLIITCLSNALYSKNVWQNENDKKLIE
                     TFSLLNVEDFFK"
     CDS             14246..15004
                     /note="O140_14"
                     /gene="wffN"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01719.1"
                     /translation="MNDLHFDDLVSIIMPTFNSIKTVKDSIKSVLEQSYLNWELLITD
                     DCSTDGTYEYLLSLDDERIRVFRNKINSGAGASRNISIKNAKGRYIAFLDSDDLWHKD
                     KLYIQISFMKSKNLGLCYSGYQKIGMNGALGKKIQPPEFVNYHQLMKSNVIGCLTAVY
                     DQNIVGKVFMPTIRKRQDMALWLKILETIDYAECAPGILAYYREGHESLSSNKIKILS
                     SQWSFYRKYMKLNLYQAIYYFSFYVTKALMKHKI"
     gene            15098..16504
                     /gene="gnd"
     CDS             15098..16504
                     /gene="gnd"
                     /note="O140_15"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ01720.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDEAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            16753..17919
                     /gene="ugd"
     CDS             16753..17919
                     /gene="ugd"
                     /note="O140_16"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ01721.1"
                     /translation="MKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKKQSP
                     IVDKEIEEYLATKDLNFRATTDKFDAYKNADYVIIATPTDYDPKTNYFNTSSVEAVIR
                     DVTEINPNAVMVIKSTIPVGFTKSIKERLGIDNLIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            18009..19043
                     /gene="wzz"
     CDS             18009..19043
                     /gene="wzz"
                     /note="O140_17"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ01722.1"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLV
                     QLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGS
                     AVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQSLPLAVSYVGETP
                     EGAQKQLAQYIQQVDDQVNEELEQDLKDNIALQMKNLQDSLKTQEVVAQEQKDLRIRQ
                     IQEALQYANQAQVTKPQIQQTQDVTQDTMFLLGSEALESMIKHEATRPLVFSSNYYQT
                     RQNLLDIDNLDVDKLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLG
                     RNALRNYNAK"
     gene            complement(19228..19839)
                     /gene="hisI"
     CDS             complement(19228..19839)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ01723.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVNIAPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVNDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHL"
BASE COUNT     6096 a   3662 c   4329 g   6074 t
ORIGIN
        1 ttacgccatc ttacgccagg gatttcataa ccagataatc ggtgccaaca tcaccaattg
       61 taagttcagc gacttacagg gcgatgccat tgaatggaac gtggcgatta acgaccgcga
      121 tattttgata tccgaccaca tcatcgagcg catcaactgt accaacggca aaatcaactg
      181 gggcatcggt ataggccttg cgggaagcac ttacgataat aattacccgg aagaccaggc
      241 agtgaaaaac tttgtcgtgg cgaatatcac gggatcggat tgtcggcagt tgatccatgt
      301 tgaaaatggt aaacattttg ttattcgtaa tatcaaagcc cgcaatatca cgccggattt
      361 cagtaagaaa gcaggcattg ataacgccac agtcgctatt tacggttgtg acaatttcgt
      421 gattgataat attgaaatga ttaatagcgc cgggatgtta atcggctatg gggtaattaa
      481 aggcaaatat ctctcgatac cgcaaaattt ccgagtgaat aatattcagc tggataatac
      541 ccaccttgct tataaattgc gcggtatcca aatctccgcc gggaatgctg tctcctttgt
      601 ggcactgact aacattgaga tgaagcgtgc gtcgctggag ttacacaaca aaccgcaaca
      661 tctttttatg cgaaatatca aggtgatgca ggaatcctca gttggacccg cattgagcat
      721 gaactttgac atgcgcaaag acgttcgcgg cgtctttatg gcgaaaaaag aaacactgct
      781 atctcttgca aatgttcatg cggtgaatga aagaggacaa agctccgtcg atatcgacag
      841 gattaatcac catattgtta atgtggaaaa gattaacttt agattgccgg aacggagaga
      901 gtagatttgc gaccattcat aaacttactg gatataatgt tctaaaagat tataatcctc
      961 acactaactg ttaaagctgg ggctgggcag cattgactac tcagggaagg tactcatctt
     1021 tatcttgtgt ttcttacgta acaaccagac taaagtgatt tatgaacgat aacgttttgc
     1081 tcataggagc ttccggattc gtaggaaccc gactacttga aacggcaatt gctgacttta
     1141 atatcaagaa cctggacaaa cagcagagcc acttttatcc agaaatcaca cagattggcg
     1201 atgttcgtga tcaacaggca ctcgaccagg cgttagccgg ttttgacact gttgtgctac
     1261 tggcagcgga acaccgcgat gacgtcagcc ctacttctct ctattatgat gtcaatgttc
     1321 agggtacccg caatgtgctg gcggccatgg aaaaaaatgg cgttaaaaat atcattttta
     1381 ccagttccgt tgctgtttat ggtttgaaca aacacaaccc tgacgaaaac catccacacg
     1441 accctttcaa ccactacggc aaaagtaagt ggcaggcaga ggaagtgctg cgtgaatggt
     1501 ataacaaagc accaacagaa cgttcattaa ccatcatccg tcctaccgtt atcttcggtg
     1561 aacgcaaccg cggtaacgtt tataacttgc tgaaacagat cgctggcggc aagtttatga
     1621 tggtgggcgc agggactaac tataagtcca tggcttatgt tggaaacatt gttgagttta
     1681 tcaagtacaa actgaagaat gttgccgcag gttatgaggt ttataactac gttgataagc
     1741 cagacctgaa catgaaccag ttggttgctg aagttgaaca aagcctgaac aaaaagatcc
     1801 cttctatgca cttgccttac ccactaggaa tgctgggtgg atattgcttt gatatcttga
     1861 gcaaaattac gggcaaaaaa tacgctgtca gctctgtgcg cgtgaaaaaa ttctgcgcaa
     1921 caacacagtt tgacgcaacg aaagtgcatt cttcaggttt tgtggcaccg tatacgctgt
     1981 cgcaaggtct ggatcgaact ctgcagtatg aattcgtcca tgccaaaaaa gacgacataa
     2041 cgtttgtttc tgagtaatgc agacgagtca gagaaaaaag gaccaggttg gactacgatt
     2101 attcggaaag aggtactgat taaattatca gtatgtggat ttccgagtaa tccgagtaac
     2161 ctagatgctg atggtgtgta gtgttatcgt aaggtttaat caaagttatg cggagctaag
     2221 ctttggtata tagccataac gtttggctaa cctgcggcaa taatttacgc actatcagcc
     2281 aattagaggt aggaaaagaa tgacgaattt aaaagcagtt ataccggtag caggtcttgg
     2341 gatgcatatg ttgcctgcca ctaaggcgat tcccaaagag atgctaccga tcgtcgacaa
     2401 accaatgatt cagtacattg ttgacgagat tgtggctgca gggatcaaag aaatcctcct
     2461 ggtaactcat gcgtccaaga acgcggtcga aaaccacttc gacacctctt atgaattaga
     2521 atctctcctt gaacagcgcg tgaagcgtca actgctggcg gaagtacaat ctatctgtcc
     2581 gccgggcgtg accattatga acgtgcgtca gggtgaacct ttaggtttag gccactccat
     2641 tttgtgtgca cgccccgcca ttggcgacaa cccatttgtc gtggtgctgc cggacgttgt
     2701 tatcgatgat gccagcgccg acccgttgcg ttacaacctt gctgccatga ttgcgcgctt
     2761 caatgaaacg ggacgcagtc aggtgctggc aaaacgtatg ccgggtgacc tctctgaata
     2821 ctccgtcatc cagaccaaag aaccactgga tcgcgaaggt aaagtcagcc gcattgttga
     2881 atttatcgaa aaaccggatc agccgcagac gctggactca gacatcatgg ccgttggtcg
     2941 ctatgtgctt tctgccgata tttggccgga acttgaacgc acgcagcctg gtgcgtgggg
     3001 acgtattcag ctgactgatg ctattgccga actggcgaaa aaacaatctg ttgatgcaat
     3061 gctgatgact ggtgacagct acgactgcgg taaaaaaatg ggttatatgc aggcgtttgt
     3121 gaagtatgga ctacgcaacc tgaaagaagg ggcgaagttc cgtaaaggca ttgagaagct
     3181 gttaagcgaa taatgaaaat ctgaccgaat gtaacggttg ataagaaaat tataacggca
     3241 gtgaagattc gtggcgaaag taatttgctg cgaatattcc tgccgttgtt ttatataaac
     3301 aatcagaata acaacgagtt agcaatagga ttttagtcaa agttttccag gattttcctt
     3361 gtttccagag cggattggta agacaattag cgtttgaatt tttcgggatt ggcgggaatg
     3421 ggtaacgctc gtcacatcgt aggcatgcat gcagtgctct ggtagctgta aagccagggg
     3481 cggtagcgtg gataatttta tttatggtga agctttggct tttaatacaa atcttaataa
     3541 aaatatagct tatcttttct tagtacaagg aagttcttat ttactacctc tcataacttt
     3601 cccatatctt gttcgtgtat tgggaccaga gttttttggg gtgctgggtt tctgccaagc
     3661 atcaatgcaa tatttggtga tgcttacaga atatggtttt aattggactg caactcaaaa
     3721 aatagccatt aataaaaatg atcgtaataa gttaacacat attttttggg gggttatctt
     3781 tgcaaaaata ctattaagtt tttttgcttt tattatgtta acattagttt gcatttttat
     3841 tgagcgctat cgcgatgttg cattgatact tgcggcgttt agccctttgg tttttggtaa
     3901 tataatttat ccaatttggt tttttcaagg attagagaag atgaaatgga tttcattgtg
     3961 tacaataacg gcacgagcaa tgttaattcc attaacgttc atttttgtaa aatcaccaga
     4021 agatgtttgg atagccgcgt taattcaggg ggcaataaat ttatttgcag gttgcatcag
     4081 cttatatata atcaaacgca ataagtgggt tggtagagtt gttttttctg taaaagatat
     4141 taaggaaaat ttagtagatg gttggcatgt atttgtttca acatctgcta taagtcttta
     4201 tacaacaagc acaactataa ttttaggatt tgtttctggt ccaattgctg tggggtattt
     4261 taatgcagcg aatacaatac gtaatgctgc acaaggctta ctcaatccgc taactcaggc
     4321 tatttatcca cggataaatt ctttatttga tacaaactat ccgcaggcat taagtttaat
     4381 taaaaaatct ttacgatata taggtttatt atctttgctc ggatcatctt ttttattcat
     4441 attggctccg tatattattt cattaacagt aggagaaaag tatttatact cagttgatat
     4501 attgaggtgg atggccttct taccatttgt acttgtttta agtaatattt ttggtgttca
     4561 aactatgttg acacatgatt ataaaaagga gtttagctac attcttatat tgagtggtgt
     4621 tcttaatcta acaattatct ttcccttggt ttataaatat tctgcaatag gtgcagccat
     4681 ttctatttta attactgaat cctttgtggc gttggcaatg tatttgtttt tgcgaataaa
     4741 gaatatatat attattaaat gagtggtgaa tcaatgtatg acttcattat agttggtgct
     4801 ggtttgtttg gggctgtttg tgccaacgaa ttgagtaaaa aaaataaaaa agttctagtt
     4861 ttagaaaaga gaaaccatat agctgggaat gcctacacgg aaaacgatga agggattcaa
     4921 gtccataagt atggagcgca tatattccat actaatgata aagaagtgtg ggagtatgta
     4981 aatttatatg ctgaatttaa tcgtttcact aattcgcctt tagcttttag cggaggtaag
     5041 ttattcaatt tacctttcaa catgaatact ttttaccaac tctggggagc tcagacccct
     5101 caggaagcta tgagtattat agatgaacag cgaagagaga ttggagaaaa aatacctaca
     5161 aatttagagg aaaaagcaat atcactagtg gggcgtgatt tatatgaaaa attaataaaa
     5221 ggttatactg agaaacaatg gggaagaaaa gcttctgagt taccagcatt tataattaac
     5281 agaatccctg tgcgtatgac atttgacaat aactatttca cagatcgctt ccagggtatc
     5341 ccggttggtg gatacactaa aatggttgag cgtatgttgg atggtattga agtacgactt
     5401 aatacagatt atctgaaaaa taagagcaat tttagaaaaa tgggaacagt tgtaatttat
     5461 actggaccga ttgatgaata ttttgaatac tgctacggta tgctcgaata tcgttcactt
     5521 agatttgaaa cctcaacact tcctgtaagt aattatcaag gaaatgcggt aattaattat
     5581 tcagaaagaa aggtgcctta cacaagaatc attgaacata aacattttga ccctgtcgat
     5641 acacctataa caaaaataac aaaagaatat ccatgtgaat ggaaagaagg agatgaacct
     5701 tattacccta taaatgatga aaagaatatg ctactcttta ataaatataa aaaactatct
     5761 aaaaatgagg acgaagtgta ttttggcggt cgtttggctg agtataaata ttatgatatg
     5821 catcaagtca ttcgtgcagc attaaattta tctagaaaat ggagttgata gatgaaatat
     5881 acgtcagttc atgtgtgttg tcctggtaat attataagtg gtggtcctga attattacat
     5941 caatttgttc atgagttaag gcagaatggc gttgatgctc atataattta ttttccattt
     6001 gaacagttgt atgatactcc tgcgttatat agtcattatg atattgccaa aagtaatatt
     6061 aatgaaataa aaaaagaaga tattgtattt ataccagaaa ccgcgacata cctaataaat
     6121 aggatctctt gtgaaaatat tgctatttgg tggctttcaa tagattttta ttatggatgt
     6181 cctgtagata aaaaaatctc tccactgatg cttaaacatt atgtcgatgt gtggaaagga
     6241 aaaaaattgt catttagtga aatgaagaag tttcaacatt ttcatcaaag ctactatgca
     6301 aaagattttt taagtcgaaa aggtataatt tctaaagaat tatctgatta tttaaatgac
     6361 gagtttatta aaactaatat attaaatagg gacaacaatc gaaaaaaaat aatagcatac
     6421 aatcctaaaa aggggataaa aaccacaaat aggttaatta aggcatttcc caattacaaa
     6481 tttgtacctt tgataaatat gaggcctaat gaaataaaga atttattaaa gagtataatg
     6541 atttatattg attttggaca tcatccgggg aaagatcgtt ttcctagaga agcagctatt
     6601 tcaggatgtt gtattattac agggcaacgg gggagcgcga aaaataatgt tgatctacca
     6661 attccagata gatttaaatt aagagataat agtaatgacc ttgaagtgaa atttggtgag
     6721 cttgtagaat caatatttga ttgttttgaa aaagaaacaa tgagctttga ggattacagg
     6781 actaaaatta gacaagagca tcaaatattt caacgaaatg tatatgaaat agcaaaaagt
     6841 tgtgctatca cgaaagagat ataattttat ataaacctaa atgatttgtc tgtaaggtat
     6901 tcgagagcat gaaaataatt gtgacgggtg gaggcggttt tatcggaact gctttgattc
     6961 attatattat atataatacg caggatagtg ttgttaatgt cgataaatta acgtacgccg
     7021 gaaacctgga gtcacttgca gatgtttctg attctgaacg atatgttttt gaacatgcgg
     7081 atatttgcga tgcagctgca atggcacgga tttttgctca gcatcagccg gatgcagtga
     7141 tgcacctggc tgctgaaagc catgtggatc gttcaattac aggccctgcg gcatttattg
     7201 aaaccaatat tgttggcact tatgtccttt tggaagcggc tcgcaattac tggtctgctc
     7261 ttgatggcaa caagaaaaat agcttccgtt ttcatcatat ttctactgac gaagtctatg
     7321 gtgatttgcc tcatcctgac gaggtaaata ataaagaagg attaccctta tttactgaga
     7381 cgacagctta cgcgccaagc agcccttatt ccgcatcaaa agcatccagc gatcatttag
     7441 tccgtgcgtg gaaacgtacc tatggtttac cgaccattgt gactaattgc tctaacaatt
     7501 atggtcctta tcatttcccg gaaaaattga ttccattgat tattctcaat gctctggaag
     7561 gtaaaacatt acctatttat ggtaaagggg atcaaattcg cgactggttg tatgttgaag
     7621 atcatgcgcg tgcgttatat accgtcgtaa ccgaaggtaa agcgggtgaa acttataaca
     7681 ttggtggaca caacgaaaag aaaaacatcg atgtagtgct cactatatgt gatttgttgg
     7741 atgagattgt accgaaagag aaatcttacc gcgagcaaat tacttatgtt gccgatcgtc
     7801 cgggacacga tcgccgttat gcgattgatg ctgagaagat tggtcgtgaa ttgggttgga
     7861 aaccacagga aacgtttgag agcgggattc gtaaaacggt ggaatggtac ctgtccaata
     7921 caaaatgggt tgataatgtg aaaagtggtg cctatcaatc gtggattgaa cagaactatg
     7981 agggccgcca gtaatgaata tcctcctttt cggcaaaaca gggcaggtag gttgggaact
     8041 acagcgttct cttgctcctc tgggtaactt gattgctctt gatatccact ccactgatta
     8101 ttgtggtgat tttagtaatc ctgaaggtgt agctgaaaca gtaagaagca ttcggcctga
     8161 tattattgtc aacgcagccg ctcacaccgc agtagacaaa gcagaatcag aaccggagtt
     8221 tgcacaatta cttaacgcga cgagtgtcga agcgatcgcg aaagcagcca atgaggtcgg
     8281 tgcctgggtt attcactact ctactgacta cgtatttccg ggaaccagtg aaataccatg
     8341 gcaggagacg gatgcaacag caccgctaaa tgtttacggt gtaaccaagt tagctggaga
     8401 aaaagcatta caagagcatt gtgcgaagca ccttattttc cggaccagct gggtctatgc
     8461 aggtaaagga aataacttcg ccaaaacgat gttacgtctg gcaaaagagc gtgaagaatt
     8521 agcggttatt aacgatcagt ttggtgcacc aacaggtgct gagctgctgg ctgattgtac
     8581 ggcgcatgcc attcgtgtgg cattgaataa gccagaagtc gcaggtttgt accatctggt
     8641 agccagtggt accacaacct ggcacgatta tgctgcgctt gtttttgaag aggcgcgcaa
     8701 agcaggcatt ccccttgcgc tcaacaagct caacgcagta ccaacatcag cctatcctac
     8761 accagctcgt cgtccacata actctcgcct taatacagaa aaatttcagc agaactttgc
     8821 gcttgtcttg cctgactggc aggttggcgt gaaacgaatg ctcaacgaat tgtttacgac
     8881 tacagcaatt taatagtttt tgcatcttgt ccgtgatgat ggagcaagat gaattaaaag
     8941 gaatgatgaa atgaaaacgc gtaaaggtat tattttagcg ggtggttctg gtactcgtct
     9001 ttatcctgtg acaatggctg tcagtaaaca gctattacct atttatgata agccgatgat
     9061 ctattatccg ctctctacac tgatgttggc gggtattcgc gatatattga ttatcagtac
     9121 gccacaggat actcctcgtt ttcaacaact actgggtgat ggtagccagt gggggctaaa
     9181 tcttcagtac aaagtgcaac cgagtccaga tggtcttgcg caggctttta tcatcggtga
     9241 agaatttatt ggtggtgatg attgtgcttt ggttcttggt gataatatct tctacggtca
     9301 cgatctaccg aagttaatgg atgtagctgt taacaaagaa ggtggtgcaa cggtatttgc
     9361 ctatcacgtt aatgatcctg aacgctacgg tgtcgttgag tttgataaaa acggtacggc
     9421 aatcagcctg gaagaaaaac cgctacaacc aaaaagtaat tatgcggtaa ccgggcttta
     9481 tttctacgat aacgacgttg tcgaaatggc gaaaaacctt aagccttctg cccgtggtga
     9541 actggaaatt accgatatta accgtattta tatggaacag ggggggttat ccgttgccat
     9601 gatgggacgt ggttatgcat ggctggacac gggtacacat caaagtctta ttgaagcaag
     9661 caacttcatt gcaacaattg aagaacgtca aggtctgaaa gtttcctgcc cagaagaaat
     9721 tgctttccgt aaagggttta ttgatgctga gcaggtgaaa gtattagctg aaccgctgaa
     9781 aaaaaatgct tatggtcagt atctgctgaa aatgatcaaa ggttagtaat aaaatgaacg
     9841 taattagaac agaaattcca gacgtactga tttttgaacc gaaagtattt ggtgatgagc
     9901 gtggtttctt ttttgagagc tttaatcaga agatttttga ggaagctgta ggccgcaaag
     9961 ttgaatttgt tcaggataac cattcgaagt ctagcaaagg tgttttacgt ggactacatt
    10021 atcagttaga accttacgca caaggaaaat tagtgcgctg tgttgtcggc gaagtttttg
    10081 atgtggcagt tgatattcgc aaatcttcac ctacctttgg taaatgggtg ggggtaaatt
    10141 tgtctgctga gaataaacgt cagctatgga tcccggaagg ttttgctcat ggatttttag
    10201 tactgtcaga ggttgcccat tttgtgtata aaactacggc gtactatagt cctaagtttg
    10261 aaagaggaat ttgctggaaa gatccttttt tatccatcga atggcctgaa attggggaag
    10321 tgttaatgtc ttttaaagat aaagagttac catcgttaat aatctaatgt caagattaat
    10381 aaaaaacgag cacaaatagt taattatcta tattccaagt aacttgggtt aaaatgaata
    10441 ttatcataag aagtgatttt ttcttggcga aattgctatt aaataatctc ccccctaaat
    10501 atattattta tggagttgaa gaacttatag atattaatga gaaattaaac agaacattct
    10561 tacataaatt aattaagtac agattaattc ctgtattcaa attaacatta tgcaatctct
    10621 tgcgatcctg ttttaaaaag cgaaacaagg ataaggtttt ttattttgat attgatagaa
    10681 tagatatttt agccagtctt atcttacgca actgggatgc agataagcaa attatctggc
    10741 tatggaatcc aacagctaaa gtgatgaaat ctacaacgca attattattt tttattaatc
    10801 ttataaaaaa aaataaagtc gaaatatgga cgtttgatca aaacgatgct tctttatatg
    10861 ggttaaaata ctataatcaa atatactctt tagcgatggt tgatttgttt aaacaaacca
    10921 ataatagtat tgatgtttta tttgtggggc aggataaaga gcgattacaa cttttgttga
    10981 tgattaaaca aaagatggat agagagaaac tagttacgta tttccatgta gttaaagatg
    11041 gaggagttac atataccaga gatgagaagg cttttctttc tgatgaaata ttaagttatg
    11101 aagattatat tcataaagtt cagcaagcca agtgtctgct agatattaat cagagtggtc
    11161 aaacaggcct aacattacgt gttcttgaag ctcttttttt taataagaaa cttataacaa
    11221 ataatccaaa cgtcgtaaaa tataattttt ataactccaa taacataatg attatagagg
    11281 ataaagttga caacgtatca tttaatgagt tcataaatag tagttatcaa gaaatagaac
    11341 aatctattaa aaatgaatat gatgttgaat ttatgctcga tacaatcttt caaacatcgt
    11401 aatttaaata caacgtgaat aaaaatgcat agaaatatta ctttaaagtt gatacttgca
    11461 tgtttgacaa cgtttgtcat gatgctattt ttcccattgt ggttaaacct attaatattc
    11521 acaataattc tttttataag cgataactca cttaagatac cagtgtctgt aatattggct
    11581 ttgctatcat ctttatttat atcaagtgtt gatattgctt atgacctaaa aaattatcat
    11641 gatctttttg tcaacattaa ctcagatatt tatacaagtg agtttaaatt tgaaccattt
    11701 ttgttgtact attactctgt tttatctcaa ttagacgttg atttcagagt tgtgcttttt
    11761 ttgcaatcac tatttttgaa tgttacactt ctgtatgttt ttataaaaac attggggatt
    11821 aaaggtataa agtattatgg tctattgttg atttttcccc aatatgtaca gttgtcattg
    11881 tttcttagtc gtcagactat ttcattatta tttgtagttt tgttaataac gtattgttta
    11941 aataataaga tgactttatt taaatttatc gttgtatcta caatagctgt ttctgcgcat
    12001 gcaatttctt tgctatatat aactataatc ttactctcat caagattaaa aaaatatctc
    12061 acatggaaaa tgttatttac tatctggctt gttggtattt taatgcctat aactgctgat
    12121 atcatgaata atattttgca gaatgtattc aatcaaatcc ctttattgga tagaaaaatt
    12181 ggattttata tgaattctgt tagcactaat atcagtgcat cattaacgct ttatagcatt
    12241 tcaatattac ctcttcatat tttatttttt atgatactct tatcaataaa aaaaaagaaa
    12301 tataaaacaa cagctactgc atttacattt gtatatttga ttgtatatta tttgattata
    12361 ttcctaataa attatccact acttccggct aggatcggtt tgttaattat tatttttaca
    12421 ccatatttct actttgttgc tataaatgta ttttacagtg acagtaaata ctataaagtt
    12481 atggaaaact ttggtgtttt gtttgtttta gccattttta tacgttttct ttttactaac
    12541 gattatggag attataacgt taatttggct aataagcata tacttgaata tagtctttca
    12601 aatttgttaa attaaagagg ttattttgaa atatattgtt ggttctggtt ggtggtgcaa
    12661 tgaaaaagag gactatcgtg aaaaatgtta tggggataat tctattagag ggaaagagtt
    12721 tcatcaaaaa tggtatgaat cgttgttatt gaatactagc ccagcggaaa tatatattgt
    12781 cgatagtgac tcacctataa agcctaactt cgataaacga atcaagtttg taagtttaaa
    12841 tgaaaatggg gggcattcta ctaatttgac tggtaaatat tcaggatgga tgcgatcagt
    12901 aatacattcg atgtcgtatg ctcagtgctg cgattgtgat tattatattt atgttgagca
    12961 ggatgtgttg cttaaaggta agggaattgt tgagtattgc atttctaaaa tgacaaaacc
    13021 atttatgttc ggtctatgcc atgatcatca caaccctttg caacaatcat tttttatcat
    13081 caaaaaggat tacattgata ttttcttatc tcggctgtat ttgataaaat ataatgattt
    13141 cgatatttca cctgaaaaaa agtttgcact tgcaacatct ccttttttcc atttgatacc
    13201 acaaatatta tttgtgaggc ctaagtcgaa actaatgcta cgattatttt ggagaattca
    13261 aaatactttg gcaaaaatat tagggagcta tgattatctt ccgattggat acggtcgtga
    13321 caggccaata aacttatcag ataaatatta ttattttcag catggtacaa tggaagaaat
    13381 taatgactat tatattcaat aagatcatat tcttattaaa gtgcttattt tccactatta
    13441 aacttcacct acgcgctatc ttttgtcgct taaatagaaa tcaatgtgtt tcgcaaaatt
    13501 cagagtatat aataacacta acatcttatc atgagcgatt taatactcta tatttaacac
    13561 ttgaatctct ttttaatcaa tcggtaaaac catctaatat atatttgtgg atatcacaag
    13621 aagatatcga taaatatggt ggtctacctg actcgctgcc tagatatata aatgcaggat
    13681 tgacagttaa aattcttaaa gaaaatatca gatcatataa gaaactttca tatatagagg
    13741 atgtgttaaa gaaagataat aacatcaaat ttataataac agctgatgat gacataatgt
    13801 atcctcgtcg ctgggcccaa gggctaatac aaacaaccaa aaaacatggt tctgtatctt
    13861 gctacagagg tcataatttg acgtatgcag aaggtagtta taattataat caaagcatta
    13921 atcaaaataa atttagtgta gaaccttctt ttgacttatt accaacaggt tgctcaggta
    13981 tttgctattt aagaaaatct attaacaaac ttgttaatga cagacgtttt ttgaattttg
    14041 cttatgatgc tgatgatata tggtataaag caatgactct ttccgcaggc ttcaaatgtg
    14101 tcagagtgga accacgaaat atacattttc ctttaattat tacttgcttg tcgaatgcgc
    14161 tatattcaaa gaatgtttgg cagaatgaaa atgataagaa attgattgaa actttttcgt
    14221 tacttaatgt agaggatttt tttaaatgaa tgatttacat tttgatgatc ttgtctcaat
    14281 tataatgcca acatttaatt caatcaaaac agtgaaggat agtattaaat cagttctaga
    14341 gcaatcttat cttaattggg aactattgat aacggacgat tgttcaactg acggaacgta
    14401 tgaatatctt ttatctcttg atgatgaacg tataagagtt tttagaaata agatcaactc
    14461 tggagccggt gcttcgagaa atataagtat aaaaaatgct aaaggaagat atattgcatt
    14521 tctagatagt gatgatttat ggcataaaga taaattatac attcagatct cttttatgaa
    14581 gtctaaaaat ttaggattat gctattctgg gtatcaaaaa attggtatga atggtgctct
    14641 gggaaaaaaa attcaaccac ctgaatttgt caattatcat caattaatga aatctaatgt
    14701 gatcggttgc ttgactgctg tctatgatca aaatattgtt ggtaaagtct ttatgcccac
    14761 aataagaaag aggcaggata tggcgctttg gttaaaaata cttgaaacga tagattatgc
    14821 tgaatgtgca ccgggaatac tagcctatta ccgcgaagga catgagagct tatcatcaaa
    14881 taaaattaaa attttgtcat cgcaatggtc tttttatcgt aaatatatga aattaaattt
    14941 atatcaagca atttattatt tttcgttcta tgttactaaa gcattgatga agcataaaat
    15001 atagaatgta ttagcataga tgttctcaat agataagcta gacgtattaa tagttatcag
    15061 aacttggtac taattcaccc cctgacagga gtaaacaatg tcaaagcaac agatcggcgt
    15121 cgtcggtatg gcagtgatgg ggcgcaacct tgcgctcaac atcgaaagcc gtggttatac
    15181 cgtctctatt ttcaaccgtt cccgtgaaaa gaccgaagaa gtgattgccg aaaatccagg
    15241 caagaaactg gttccttact atacggtgaa agagtttgtt gaatctctgg aaacgcctcg
    15301 tcgcatcctg ttaatggtga aagcaggtgc aggcacggat gctgctattg attctctcaa
    15361 gccatacctc gataaaggcg acatcatcat tgatggtggt aacaccttct tccaggacac
    15421 cattcgtcgt aaccgtgagc tgtctgccga aggttttaac ttcattggta ccggtgtttc
    15481 cggtggtgag gagggcgcac taaaaggtcc ttccattatg cctggtggcc agaaagaagc
    15541 ctatgaactg gttgctccga tcctaaccaa aatcgccgca gtggctgaag acggtgagcc
    15601 atgcgttacc tatattggtg ccgatggtgc aggtcactat gtgaagatgg ttcacaacgg
    15661 tattgaatac ggcgatatgc agctgattgc tgaagcctat tctctgctta aaggtggcct
    15721 gaacctcacc aacgaagaac tggcgcagac ctttaccgag tggaataacg gtgaactgag
    15781 cagctacctg atcgacatca ccaaagatat cttcaccaaa aaagatgaag acggtaacta
    15841 cctggttgat gtgattctgg atgaagcggc taacaaaggt accggtaaat ggaccagcca
    15901 gagcgcgctg gatctcggcg aaccgctgtc cctgattacc gagtctgtgt ttgcacgtta
    15961 tatctcttct ctgaaagatc agcgtgttgc cgcatctaaa gttctctctg gcccgcaagc
    16021 acagccagca ggcgacgagg ctgagttcat cgaaaaagtt cgtcgtgcgc tgtatctggg
    16081 caaaatcgtt tcttacgccc agggcttctc tcagctgcgt gctgcgtctg aagagtacaa
    16141 ctgggatctg aactacggcg aaatcgcgaa gattttccgt gctggctgca tcatccgtgc
    16201 gcagttcctg cagaaaatca ccgatgccta tgccgaaaat ccgcagatcg ctaacctgct
    16261 gctggctccg tacttcaagc aaattgccga tgactaccag caggcgctgc gcgatgtcgt
    16321 cgcttatgcg gtacagaacg gtattccggt tccgaccttc gccgctgcgg ttgcctatta
    16381 tgacagctac cgcgccgctg ttctgcctgc gaacctgatc caggcacagc gtgactattt
    16441 cggtgcgcat acttataagc gcattgataa agaaggtgtg ttccataccg aatggctgga
    16501 ttaatctgat ttaaatcaat taatcaatgc aaggcccgga gaaaccctcc gggctttttt
    16561 attatacaaa gcggcaggtt atggcctttt tttataattt atagttaaaa acgcgatata
    16621 atacagcgcc gcacagcagg atcgctgcct tgacagttca accgcatcag cgttaaaaat
    16681 cccgcagtag atgaagttgt ggtggtggac taatgaccac tctaaatgtt taaccggaag
    16741 aagtcagagc taatgaaaat aacaatttca ggaacaggtt atgttggtct ttcaaatggt
    16801 attctgattg cgcaaaacca cgaagtggtt gcactggata tcgttcaggc caaagtggac
    16861 atgcttaaca agaagcagtc accgattgtt gataaggaga ttgaagagta tctggcgact
    16921 aaagatctca atttccgcgc tacgacagat aagtttgacg cgtataaaaa tgccgattac
    16981 gttattattg ccacgcctac cgattatgac ccgaaaacaa attattttaa tacctcaagc
    17041 gtggaagcgg tcattcgcga tgtgacagaa attaatccta atgctgtcat ggtgattaaa
    17101 tctacaattc cggtaggttt caccaaatca attaaagaac gtctgggtat cgataacctt
    17161 attttctctc cggaattcct ccgcgaaggt aaagctcttt acgataacct tcatccgtca
    17221 cgtattgtca tcggtgagcg ttcagaacgc gcagaacgtt ttgcggcgtt attacaggaa
    17281 ggcgcgatta agcaaaatat ccctacactg tttaccgact ccactgaagc agaagcgatt
    17341 aaactgtttg ctaataccta tctggcgatg cgcgtagcat actttaatga actggatagc
    17401 tatgcagaaa gtttaggtct gaatactcgc cagattatcg aaggcgtttg tctcgatcca
    17461 cgcattggca accattacaa caatccgtcg tttggttatg gtggttattg tctgccgaaa
    17521 gataccaagc agttactggc gaactaccag tctgtgccga ataacctgat ctcggcaatt
    17581 gtcgatgcta accgcacgcg taaagacttt attgccgatg ccattttgtc acgcaagccg
    17641 caagtggtgg gtatttatcg tctgattatg aagagtgggt cagataactt ccgtgcgtct
    17701 tccattcagg ggattatgaa acgtatcaag gcgaaaggcg ttgaagtgat catctacgaa
    17761 ccggtgatga aagaagattc attcttcaac tctcgcctgg aacgtgatct cgccaccttc
    17821 aaacaacaag ccgacgtcat tatttccaac cgtatggcag aagagcttaa ggatgtggca
    17881 gacaaagtct acacccgcga tctctttggc agtgactaac atcctgttat cagggcgatt
    17941 ttcgccctga ttctcttatg ttccctttgt aataattcat tatttttatc atttatccta
    18001 tagcattcat ggcgattatc gctaaactat ggcgacttaa aattatttcg tccgttaggg
    18061 taatgatgag agtagaaaat aataatgttt ctgggcaaaa ccatgacccg gaacagattg
    18121 atttgattga tttactggtg cagttgtggc gcggcaagat gacaattatc atctctgtca
    18181 ttgttgctat tgccctggct atagggtatc tggccgttgc caaagaaaag tggacttcca
    18241 cagctatcgt tactcaacct gatgtggggc aaatcgctgg ttataccaac gcgatgaatg
    18301 tgatctacgg atcggctgta ccgaaagtct ccgacattca ggcttcgctt atcggacgtt
    18361 acagcactgc attctcagca ttagcggaaa cgctggataa ccaggaagaa gctgagaagc
    18421 tgaccattga gcctaccgtt aaaaaccagt cgttaccatt ggcggtgtct tatgtgggtg
    18481 aaacacctga aggtgcgcag aaacagctgg cgcagtatat ccagcaagtt gacgaccagg
    18541 taaatgaaga actggaacaa gacctaaaag acaacatcgc gctgcaaatg aaaaacttgc
    18601 aggattctct gaagacgcag gaagtggtcg ctcaagaaca gaaagatctg cgtatccgtc
    18661 agattcagga agcgttgcag tatgcgaatc aggcgcaggt gacaaagccg cagattcagc
    18721 agacacagga cgtaacccag gatactatgt tccttttggg gagcgaagcg ctggagtcga
    18781 tgattaagca cgaggcgact cgtccgttgg tgttctcatc aaactactat cagactcgtc
    18841 aaaacctgct ggatatcgac aatcttgacg ttgataaact tgatattcat gcttaccgct
    18901 atgtaatgaa accgacgtta cctattcgtc gcgatagccc gaaaaaggca attaccttga
    18961 ttctggcggt gctgctgggc ggcatggttg gcgcggggat tgtgttgggg cgtaacgctc
    19021 tgcgtaatta caacgcgaaa taatattatt gtgcatttaa gagaaacggg cagggtggtg
    19081 acaccatgcc cgtttttttg ccggatgcga tgctggcgta tcttatccgg cctacgtgtg
    19141 ttgagataat gtgtaggcac gataagcttg cgcatcgggc aatggctccg ggtgtgacaa
    19201 caacatcaca cctgctcagc ccgcaactca cagatgtcgt ttacgcaggt tctcaattac
    19261 cgtcgttaaa tccagatcct gatcctgtaa cagcaccagc aggtgataca tcaaatcaga
    19321 ggcttcgttg gttaattcga agcggtcatt gaccgtcgcg gccagcgcag tttccacgcc
    19381 ttcttcaccc actttctgtg cgatgcgctt ggtgccactg gcatacagtt tggctgtgta
    19441 ggaggtttct ggatcggcag atttgcgttc ggcgagcagt tgttccagtt gatacagaaa
    19501 cagccactgg tgagcggtgt cgccgaagca gctgctggtg cctttgtggc aggttggtcc
    19561 gataggattc gccagtacca gtagcgtgtc gttgtcgcag tccggcgcaa tatttactac
    19621 gttgaggaaa ttgcccgacg tttcgccttt ggtccacagt cgctgtttag tgcgcgagaa
    19681 gaaggtgact ttaccgcttt cgatggtttt gtctaaggct tccgggttca tgtagcccag
    19741 cattagcact tcgccggata ccgcgtgttg cacaatcacc ggcatcagac cgtcggtttt
    19801 ttcccagtcc agttcgcgac gttgttgttc tgttaacata tcctgatctc cacgccctgt
    19861 gttgccaggt acgcttttaa ttcaccaata ttgattattt gtttgtggaa tacggaagct
    19921 gccagcgcgc cgtcaacgtc ggcatcacgg aaggcttcga ggaagtgttc catggtgccc
    19981 gcgccaccgg aggcaattag cgggacgtgg caaacttcac gcactttttt cagttgttcg
    20041 aggtcgtaac cgttacgcac gccgtcctga ttcatcatgt tgaggacgat ttctccggca
    20101 ccgcgttttt gcacttcctg tacccagtcg agcgtttccc actgagtgac gcgggtgcgg
    20161 c
//
