LOCUS       AB812061               18883 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli genes for O-antigen biosynthetic locus, partial
            sequence, strain: C771.
ACCESSION   AB812061
VERSION     AB812061.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 18883)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..18883
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="C771"
                     /db_xref="taxon:562"
                     /note="serogroup:O142"
     gene            <1..949
                     /gene="gne"
     CDS             <1..949
                     /gene="gnu"
                     /note="O142_01"
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4-epimerase"
                     /protein_id="BAQ01724.1"
                     /translation="RLLETAIADFNIKNLDKQQSHFYPEITQIGDVRDQQTLDQALAG
                     FDTVVLLAAEHRDDVSPTSLYYDVNVQGTRNVLAAMEKNGVKNIIFTSSVAVYGLNKH
                     NPDENHPHDPFNHYGKSKWQAEEVLREWYNKAPTERSLTIIRPTVIFGERNRGNVYNL
                     LKQIAGGKFMMVGAGTNYKSMAYVGNIVEFIKYKLKNVAAGYEVYNYVDKPDLNMNQL
                     VAEVEQSLNKKIPSMHLPYPLGMLGGYCFDILSKITGKKYAVSSVRVKKFCATTQFDA
                     TKVHSSGFVAPYTLSQGLDRTLQYEFVHAKKDDITFVSE"
     gene            1192..2085
                     /gene="galF"
     CDS             1192..2085
                     /gene="galF"
                     /note="O142_02"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ01725.1"
                     /translation="MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEILLVTHASKNAVENHFDTSYELESLLELRVKRQLLAEVQSICPPGVTIMNV
                     RQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRS
                     QVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLS
                     ADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFRKGIEKLLSE"
     CDS             2460..3476
                     /note="O142_03"
                     /gene="wbwH"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01726.1"
                     /translation="MSNIAFIVTKSEIGGAQTWTNDMMELVRNGNTVHLITSEIGWLT
                     EQNNYDNCFLLPQLKKKFSFWGYLSLLKYIKKEKINVMVASSANAGIFSRLCKLFHRF
                     KCIYVSHGWSCIYNGGAFKRIFIKVEKYLSYLTDVVWCVSYSDEISAKEKIGIKRKKI
                     KMVHNSVSGIPKKLHAGEKKKVIFVGRLTHPKRPELLARVISKNPDIYLDIAGGGEYL
                     DKLKEEFESYKNINFLGEVNSFNQYLNYDIFALISDSEGLPMSALEAHTAGIPLLMSD
                     VGGCKELVSGNGLLVSNDEKDIERKLRKIIDEYDCYFLCSQADKNKFEFKNYIEKYKE
                     IILT"
     gene            3496..4581
                     /gene="rmlB"
     CDS             3496..4581
                     /gene="rmlB"
                     /note="O142_04"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6 dehydratase"
                     /protein_id="BAQ01727.1"
                     /translation="MKIFVTGGAGFIGSAVVRYIINNTQDCVVNIDKLTYAGNLESLS
                     VVANNERYSFEHADICDLEAMVRIFNEYQPDAVMHLAAESHVDRSISGPAAFIETNIL
                     GTYVLLEAARQYWCTLNDVKKEKFRFHHISTDEVYGDLPHPDEVEQGTPLPLFTEKTA
                     YAPSSPYSASKASSDHLVRAWLRTYGLPTIITNCSNNYGPYQFPEKLIPLVILNALAG
                     KSLPIYGKGDQIRDWLYVEDHACALYSVLTKGKPGETYNLGGYNEKKNLDVIHNICDL
                     LDEIIPKETSYREQITYVADRPGHDRRYAIDADKIMRELGWKPVETFESGIRKTVEWY
                     LANTLWVENIKSGTYQRWIEQNYRERQ"
     gene            4581..5480
                     /gene="rmlD"
     CDS             4581..5480
                     /gene="rmlD"
                     /note="O142_05"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAQ01728.1"
                     /translation="MNILLFGKNGQVGWELQRSLAPLGNLIALDVHSTDYCGDFSNPQ
                     GVAETIRCVRPDVIVNAAAHTAVDKAESEIDYALLLNAISVEALAKAADEIGAWVVHY
                     STDYVFPGTGETAWLETDETAPLNVYGETKLAGEKALQVNCSKHLIFRTSWVYAVNGN
                     NFAKTMLRLAQEHQMLSVINDQFGAPTGAELLADCTAHAIRIALNKPEVAGLYHLVAS
                     GTTTWYEYASLVFEEARKFGIELAVTHVNGVPTSTYATPARRPINSRLNTDKFQNKFG
                     LVLPNWEIGVKRMLTEIFTLTTI"
     gene            5532..6410
                     /gene="rmlA"
     CDS             5532..6410
                     /gene="rmlA"
                     /note="O142_06"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="BAQ01729.1"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFEQLLGDGTQWGLNLQYQVQPRPDGLAQAFIIGEEFIGK
                     DDCALVLGDNIFYGHDLPKLTDIAVNKKSGATVFAYHVNDPERYGVIEFDKDGTAISL
                     EEKPLVPKSNYAVTGLYFYDNSVIEMAKNLKPSVRGELEITDINRIYMEQGKLCVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAFRKGFIDAEQVKKLAAPL
                     SKNAYGQYLLKMINGD"
     gene            6400..6972
                     /gene="rmlC"
     CDS             6400..6972
                     /gene="rmlC"
                     /note="O142_07"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="BAQ01730.1"
                     /translation="MVINKMNVIKTEIPDVLIFEPKVFCDARGFFFESFNLKIFAEAV
                     GRNVEFVQDNHSKSKKGVLRGLHYQVAPFAQGKLVRCIAGEVYDVAVDLRKSSPTFAK
                     WVGVNLSAKNKRQLWIPEGFAHGFMVLSDEAEFVYKTTNYYSPKSERSINYADSQINI
                     KWPSSFNLKLSRKDEIAPQLAIILENELFE"
     gene            6969..8213
                     /gene="wzx"
     CDS             6969..8213
                     /gene="wzx"
                     /note="O142_08"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAQ01731.1"
                     /translation="MSIIKNSLWNVVGYIVPAIVTIPALGILGRILGAETFGVFTLAL
                     AIVGYASIFDVGLSRAVIREIALFRDDQEEKRRIIFTASLLVTVMGVTAALVLYIASD
                     VIANLLKISSELHLSVVNSLHILSLSIPVYLVTQIWLAILEGEEKFGLLNIYKSITGS
                     LISLLPVICIFISPSIEYAIIGLVVSRLVCMLFAFFLCKRIIVESYFEFSKLTLKRML
                     MFGGWITVSNIISPLMAYFDRFIVSNQLGAAVVAFYTAPSEIIARLGIVPGAFARAIF
                     PRLSCSNDVHDRKKNKKIVSLLLFLITVPVFIVGLLASNKFMVLWMGPEFAGTSANIL
                     VILLLGFVFNSLAQVPFASIQSRGYAKITAYIHMVELIPYLMALFYFINNYGIIGAAY
                     AWSIRVTIDYILLAFFDRCFDK"
     gene            8265..9446
                     /gene="wzy"
     CDS             8265..9446
                     /gene="wzy"
                     /note="O142_09"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAQ01732.1"
                     /translation="MLYVLTFALITSFGLFIALYLVKCNFTSPLSLHCFAWFFVSSTG
                     LFAYDEFIDFPEISFYAVMIWYLIVYFILITGELISLNIKSVNYFKNKEYICGRYWII
                     VIPLSAYTIYEIYRVGNTGPASFFLNLRLANIIDDYEGEKFTLMTAIYPVLIAMFSIV
                     CISCSSKKNKYALWLWSILFCIGTMGKFAVITPILIFYIIRELTGGLNKKRMVFIVPG
                     VISAILFMHFIRMSSGDSTTISSVLGVYIYSPLLALSKLPELNINGESGEYTFRFLIA
                     ILYKVGLSSNEPVKTILDYVNVPVPTNVFTVMQPFYQDYSLFGVAFGAIFYGIIYSSI
                     YLLAKKGNPVALLIYAVLAISLFTSFFAETLITNLAGNIKVVICIYLLWRFTVRCKIK
                     P"
     CDS             9455..10363
                     /note="O142_10"
                     /gene="wbuG"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01733.1"
                     /translation="MATYNGSAFIENQILSLQQQKYKDWILYIHDDGSSDDTLDIIKR
                     IQLTEPRINLIEDGLTRLGAGKNFLSLVKYSATNYTIFCDQDDIWLENKLSEMIVFAD
                     SKGLASSKLPSMIYADGYAFDDSTGEIDFCGISHNHATRLKDFLFFNAGYQGCSILFN
                     KAMVDIAANYHGYVHLHDDVVSLIAHSLGNVYFLPKKLMLYRQHLGAVTGQKKFNNRF
                     ISMLTSKVNYLLSREHFLVKRSFYDNYHHLLTAEIKNDFEVFFKFCQTKNKLSQLVLL
                     LKHDFRLNNSRLKLLLKCIVRRTFSQ"
     CDS             10360..11148
                     /note="O142_11"
                     /gene="wclU"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01734.1"
                     /translation="MISVLTPTYNRAYTLKRLYESLICQTTKSFEWVVVNDGSNDETE
                     SIIKEFQQQNIIKIIYYKQENKGKTQALNAGIQLCAGSDILIVDSDDLLTSDAIACIE
                     ASLTQEKIYNKKISGVAFRKAYLDETIIGTVFDDSVDSFCYLSATDAGHLFKGDLAYC
                     FKKEMLQMFPFPYFYNEKFVPELYIWNKITDHALVKFHKKKAVYLCEYLEDGLSKNFK
                     TQLLKNPKGFSIYYIDQFKRETNYIRKLKMLIRYFQCKLYELKK"
     CDS             11145..12239
                     /note="O142_12"
                     /gene="wbtF"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01735.1"
                     /translation="MNIVFVITGLGLGGAEKQVCLLADRLAEAEHQISIVSLTGECVV
                     KPDNKHIEIYHLNMDKSLISFFLGVIKLRNIISTIKPDIVHSHMFHANIMSRLSKLLL
                     PYSHKLICTAHSRYEGGRLRMLCYRLTDYFSDINTNVSKEALDEYVNNKYFSATKSIV
                     VYNGVDTEKFNFSIDNRIYIREQLSINNHDRLILSVGRLNPAKDYPNLLAAFMLLPEH
                     YKLVIIGEGDVRSQIEQIIKDHKLGTRVQLLGSVNNVNDYYSACDLFVLSSAWEGFSL
                     VVIEAMACQRIAVCTDAGGVKEAFTDRHYIVPTSNAAALARKIIEVDMLTIDRKNEIQ
                     NDNRNNVVNKFSINAIVNHWLTIYKNITMQ"
     CDS             12483..13502
                     /note="O142_13"
                     /gene="gne"
                     /codon_start=1
                     /transl_table=11
                     /product="putative UDP-glucose 4-epimerase"
                     /protein_id="BAQ01736.1"
                     /translation="MTILVTGGAGYIGSHTVVRLLEKGKEIVILDDFTNSFPETLNRI
                     KIITGVKPFFYEGSVLDRNLLKKIFVENNITDVIHFAGLKSVGESVSSPLKYYEVNIA
                     GSLHLVEEMITHNISNFIFSSSATVYGEPETIPLTESSRIGGTTNPYGTSKLMVEKIL
                     EDVTRSNPEFRTTILRYFNPVGAHPSGDMGEDPNGIPNNLMPYICQVAIGKYKQVSVY
                     GSDYPTKDGTGVRDFIHVMDLAEGHVAALEHRNKGPNHKVYNLGTGTGYSVLELLTAF
                     ERVTSRKVPYVLSERRPGDIAECWSNPSKAYAELGWKAKRGLEDMVRDAWNWQQKNPN
                     GYKKE"
     gene            13622..15028
                     /gene="gnd"
     CDS             13622..15028
                     /gene="gnd"
                     /note="O142_14"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ01737.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGEKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFSASVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            15276..16442
                     /gene="ugd"
     CDS             15276..16442
                     /gene="ugd"
                     /note="O142_15"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ01738.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILQSRVAMLNDRISP
                     IVDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            16532..17566
                     /gene="wzz"
     CDS             16532..17566
                     /gene="wzz"
                     /note="O142_16"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ01739.1"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLV
                     QLWRGKMTIIISVIVAIALAIGYLTVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGP
                     AVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQSLPLAVSYVGETP
                     EGAQKQLAKYIQQVDDQVNEELEQDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQ
                     IQEALQYANQAQVTKPQIQQTQDVTQDTMFLLGSEALESMIKHEATRPLVFSPNYYQT
                     RQNLLDIENLKADDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLG
                     RNALRNYNAK"
     gene            complement(17752..18363)
                     /gene="hisI"
     CDS             complement(17752..18363)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ01740.1"
                     /translation="MLTEQQRRELDWEKIDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVSIAPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ"
BASE COUNT     5533 a   3482 c   4125 g   5743 t
ORIGIN
        1 ccgactactt gaaacggcaa ttgctgactt taatatcaag aacctggaca aacagcagag
       61 ccacttttat ccagaaatca cacagattgg cgatgttcgt gatcaacaga cactcgacca
      121 ggcgttagcc ggttttgaca ctgttgtact actggcagcg gaacaccgcg atgatgtcag
      181 ccctacttct ctctattatg atgtcaacgt tcagggtacc cgcaatgtgc tggcggccat
      241 ggaaaaaaat ggcgttaaaa atatcatctt taccagttcc gttgctgttt atggtttgaa
      301 caaacataac cctgacgaaa accatccaca cgaccctttc aaccactacg gcaaaagtaa
      361 gtggcaggca gaggaggtgc tgcgtgaatg gtataacaaa gcaccaacag aacgttcatt
      421 aaccatcatc cgtcctaccg ttatcttcgg tgaacgcaac cgcggtaacg tctataactt
      481 gctgaaacag atcgctggcg gcaagtttat gatggtgggc gcagggacta actataagtc
      541 catggcttat gttggaaaca ttgttgagtt tattaagtac aaactgaaga atgttgccgc
      601 aggttatgag gtttataact acgttgataa gccagacctg aacatgaacc agttggttgc
      661 tgaagttgaa caaagcctga acaaaaagat cccttctatg cacttgcctt acccactagg
      721 aatgctgggt ggatattgct ttgatatcct gagcaaaatt acgggcaaaa aatacgctgt
      781 cagctctgtg cgcgtgaaaa aattctgcgc aacaacacag tttgacgcaa cgaaagtgca
      841 ttcttcaggt tttgtggcac cgtatacgct gtcgcaaggt ctggatcgaa ctctgcagta
      901 tgaattcgtt catgccaaaa aagacgacat aacgtttgtt tctgagtaat gcagacgagt
      961 cagagaaaaa aggaccaggt tggactacga ttattcggaa agaggtactg attaaattat
     1021 cagtatgtgg atttccgagt aatccgagta acccagatgc tgatggtgtg tagtgttatt
     1081 gtaaggttta atcaaagtta tgcggaacta agctttggta tatagccata acgtttggct
     1141 aacctatggc aataatttac acactatcag ccacttagag gtaggaaaat aatgacgaat
     1201 ttaaaagcag ttataccggt agcgggtctt gggatgcata tgttgcctgc cactaaggcg
     1261 attcccaaag agatgctacc gatcgtcgac aagccaatga ttcagtacat tgttgacgag
     1321 attgtggctg cagggatcaa agaaatcctc ctggtaactc acgcgtccaa gaacgcagtc
     1381 gaaaaccact tcgacacctc ttatgaatta gaatctctcc ttgaactgcg cgtgaagcgc
     1441 caactgctgg cggaagtaca gtccatctgt ccgccgggcg tgaccattat gaacgtgcgt
     1501 cagggcgaac ctttaggttt aggccactcc attttatgtg cacgacctgc cattggtgac
     1561 aacccatttg tcgtggtgct gccagacgtt gttatcgatg acgccagcgc cgacccgctg
     1621 cgctacaacc ttgctgccat gattgcgcgc ttcaatgaaa cgggccgtag ccaagtgctg
     1681 gcaaaacgta tgccgggtga cctctctgaa tactccgtca ttcaaaccaa agagccgctg
     1741 gatcgggaag gtaaagtcag ccgcattgtt gaattcatcg aaaagccgga tcagccgcag
     1801 acgctggact cagacatcat ggccgtgggt cgctatgtgc tttctgccga tatttggccg
     1861 gaacttgaac gcactcagcc tggtgcatgg gggcgtattc aactgactga tgccatcgct
     1921 gaactggcga aaaaacagtc cgttgatgcc atgctgatga ccggtgacag ctacgactgc
     1981 ggtaaaaaaa tgggctatat gcaggcgttc gtgaagtatg gattacgcaa cctgaaagaa
     2041 ggggcgaaat tccgtaaagg gattgagaag ttgctaagcg agtgagctta aaaaatcatg
     2101 ttctttatga gcatagaact gtattggttg ataatcattc gaagaagtta ggtcaatact
     2161 tcgaaaatat tgctgccgtt ttgttttaga ggaactttgt taaagtttat agagttatat
     2221 attaaggtca gacctacatt ttataaaatt tactcttgtt tcttacatca ataggtaaga
     2281 caattggtct ttaactttcg ggactttgcg cactaggcaa agttagatat acctatggta
     2341 gtatgtagcg cactggttgc tgttaagcca ggggcggtag cgtgcttaaa taatagcaac
     2401 tctattttag ataattgaac gattatgtaa aatacagacc aacataaatt aacatcgata
     2461 tgagcaacat agcatttatt gtgacaaaat ctgagattgg tggtgcacaa acttggacta
     2521 acgatatgat ggaattagtc agaaatggta atactgtgca tttgattacc tctgaaattg
     2581 gatggctgac tgaacaaaat aattacgata actgtttttt attaccacag ctaaagaaaa
     2641 aatttagctt ttggggttac ttgtctctcc ttaaatatat taaaaaagaa aaaataaatg
     2701 taatggtggc gagttctgct aatgcaggta ttttttcaag attatgtaaa ctatttcata
     2761 gatttaaatg catttatgta tcgcatggtt ggtcctgtat ttataatgga ggtgctttta
     2821 aacgaatatt tattaaggta gagaaatact tgtcgtattt aacagatgtt gtttggtgtg
     2881 tatcttatag tgatgaaata agtgcgaaag aaaaaatagg cataaaaaga aaaaagatta
     2941 aaatggtaca taactctgta tcaggtatac ccaaaaagtt acatgcagga gaaaagaaaa
     3001 aagtaatttt tgtaggtcgc cttactcatc ctaaacgtcc tgaattattg gctcgagtaa
     3061 tttctaaaaa tccagatata taccttgata tagcgggagg aggtgagtat ctggataagc
     3121 taaaagaaga gtttgaaagt tataagaata ttaatttcct tggggaagtc aactctttta
     3181 atcagtatct taattatgat atttttgccc taatttcaga tagtgaagga cttcccatgt
     3241 ctgcattaga ggcccataca gcgggaattc cactcttgat gagtgatgtt gggggatgta
     3301 aagagttggt gagtggtaat ggcttgctgg tttctaatga tgaaaaagat attgaaagaa
     3361 agctccgaaa aattattgac gaatatgatt gttatttttt atgttcacaa gctgataaaa
     3421 ataaatttga gttcaaaaac tatattgaaa aatataaaga aataatatta acgtgatatt
     3481 tttagtgagt ttaaaatgaa aatatttgtt actggtggag cgggttttat tggatctgct
     3541 gttgtacgtt atattataaa taatacacaa gactgtgttg tcaatattga taaattaacg
     3601 tatgcaggta acctcgaatc actgagcgtt gtcgcaaata atgaacgcta ttcttttgag
     3661 catgcagata tatgtgactt agaagctatg gtgcgaatct tcaatgaata tcaacctgat
     3721 gcagttatgc atctcgctgc tgagagccat gtagatcgat ccatctctgg ccccgcagcc
     3781 ttcatagaaa ctaatattct ggggacttac gtccttctgg aagctgcacg ccagtattgg
     3841 tgcacactca atgatgtgaa aaaagagaaa ttccgttttc atcatatttc aactgacgaa
     3901 gtctatggcg atctacccca tccggacgaa gttgagcagg ggacacctct tcctcttttc
     3961 acagagaaaa cagcttatgc gccaagcagt ccttattctg cttctaaagc ctccagcgat
     4021 catctggttc gcgcatggct gcgtacctat ggtttaccaa ccattatcac caactgctca
     4081 aataattacg gtccatatca atttccggaa aaactgattc ccttggttat cctaaatgcg
     4141 ctcgcaggta aatcattacc gatttatggc aaaggcgatc agattcgcga ctggctttat
     4201 gtcgaggacc atgcttgcgc actttattcc gtgctgacaa aaggtaagcc tggagaaacc
     4261 tataatcttg gcgggtacaa cgagaagaaa aatctcgacg taattcataa tatttgtgat
     4321 ctgctcgatg agatcatacc caaagagaca tcatatcgtg aacaaattac ttatgtggct
     4381 gacagacccg gacatgatcg tcgttatgct attgatgcag ataaaattat gcgtgagtta
     4441 ggatggaaac ctgtggaaac attcgaaagc gggattcgta aaaccgttga gtggtatctg
     4501 gcaaatactc tttgggtaga aaacatcaaa agcgggacat atcaaaggtg gatcgagcag
     4561 aactacaggg agcgccagta atgaatattc tgttgtttgg taaaaatgga caggtaggat
     4621 gggaactaca acgttcgctc gctcctcttg gaaatcttat agcgctggat gttcattcaa
     4681 cagattactg tggtgatttt agtaatcccc aaggtgtggc tgaaaccatc cgttgtgttc
     4741 gcccggatgt aattgtcaat gctgccgccc atacggccgt cgataaagca gaaagtgaga
     4801 ttgattatgc gctattactc aatgcgatta gcgtagaagc gctcgctaaa gctgccgatg
     4861 aaattggtgc atgggttgtg cattattcga cagattacgt tttccctgga acaggagaaa
     4921 cggcatggct tgaaactgac gagacagcac cgctgaacgt ttatggtgaa acgaaacttg
     4981 cgggcgaaaa agctcttcag gtaaattgca gtaagcatct aatttttcgt actagctggg
     5041 tttatgcagt taacgggaat aatttcgcga agacaatgtt gcgtcttgca caagaacatc
     5101 aaatgttgtc cgttataaac gatcagtttg gcgcaccgac gggagcggaa ttgctagcag
     5161 attgtacggc acatgctatt cggattgcat tgaataagcc agaggttgca ggtctttatc
     5221 atctggttgc gagtggaacg acaacttggt atgaatatgc atccttagtt tttgaagaag
     5281 cacgtaaatt cggtatcgaa ttggccgtaa ctcatgttaa tggtgtgcca acaagcactt
     5341 atgctactcc agcacggcgt ccaattaatt cccggttaaa tactgataag tttcaaaata
     5401 aatttggatt agtattgcca aattgggaaa taggtgtcaa acgtatgttg actgagattt
     5461 ttacattaac gacaatctga ttttaatttt tatgtcagcc ttcgagtatt ttgcgtttaa
     5521 gagaaattaa catgaaaaca cgtaaaggga ttattctggc cggtggttcc ggtacacgtc
     5581 tgtatccagt gactatggct gttagtaaac aattgttgcc tatttatgat aagccgatga
     5641 tttattatcc actctcgacg ctaatgctgg cggggattcg ggatatactt attattagca
     5701 ccccacagga tacaccccgg tttgaacaat tgctcggaga cggaactcaa tggggattga
     5761 atcttcaata tcaagtacag ccaaggccgg atggtttggc gcaagcattt attattggtg
     5821 aagagttcat tggtaaagat gattgtgctc tagtattggg cgataatatt ttctatggac
     5881 atgatttacc aaaactcact gatatcgcag ttaataaaaa aagtggtgca actgtttttg
     5941 catatcacgt taatgatccg gaacgttatg gcgttattga gtttgataaa gatggtacag
     6001 cgatatcttt agaagaaaaa ccgctagtgc caaaaagtaa ttatgctgta actgggcttt
     6061 atttctatga caacagtgtg attgaaatgg ctaaaaatct caagccttcc gtgcgtggag
     6121 agctggaaat caccgatatc aaccgtattt atatggagca gggaaaactt tgtgtcgcca
     6181 tgatggggag gggctatgct tggctggata cgggaacaca tcaaagcctg atagaagcga
     6241 gcaactttat tgctactatt gaagagcgtc agggattgaa agtttcttgt ccggaagaga
     6301 tagcgtttcg caagggtttt attgatgctg agcaggttaa aaaactagca gcaccgttat
     6361 caaagaatgc ctatggacaa tatctcctta agatgattaa tggtgattaa taaaatgaat
     6421 gtaattaaaa cagaaatccc tgatgtactc atttttgagc caaaagtttt ttgcgatgct
     6481 cgtggttttt tctttgagag ttttaatctg aaaatatttg cagaggccgt tggtagaaac
     6541 gttgaatttg ttcaggacaa tcattcaaaa tccaaaaaag gggttttacg aggtcttcac
     6601 tatcaggtag ccccgtttgc tcagggaaaa ttagtgagat gcattgctgg tgaagtatat
     6661 gatgtcgctg ttgatctacg taaatcatct ccgacctttg ctaaatgggt tggtgtaaat
     6721 ctttcggcta agaataaacg ccaattgtgg attcctgaag gattcgcgca tggttttatg
     6781 gtgttgagtg atgaagctga atttgtatac aaaactacga attattatag ccccaaatca
     6841 gaacgttcaa taaactatgc cgactcacag ataaatatta agtggccgtc aagttttaat
     6901 ttgaaacttt cacggaaaga cgaaattgca cctcagttgg ctattatttt agaaaatgag
     6961 ctttttgaat gagcattata aaaaacagtc tttggaatgt tgtcgggtat attgtccctg
     7021 ctattgtcac gatccctgcg ttgggaatat taggtcgaat cttaggtgca gaaaccttcg
     7081 gtgtatttac tcttgcgcta gcaatagttg ggtacgctag tatttttgat gtaggcttat
     7141 caagagctgt tattcgagaa atagcgttat ttcgagatga tcaagaagaa aaaagaagaa
     7201 taatattcac agcatcatta ttagttacag taatgggagt tactgctgca ttagtattgt
     7261 atattgcaag tgatgtaata gctaatttgt tgaagatcag ctctgagtta catttgagtg
     7321 ttgttaattc tctacatata ctctcactct ccatccccgt ttatttggta acacaaatat
     7381 ggcttgcaat tctagaggga gaagagaagt ttggtctatt aaatatttat aaatctatta
     7441 ctggttctct aatttcacta cttccggtta tttgtatctt tatttctccc tccattgagt
     7501 atgctattat tggcttggtt gtatctcgat tggtttgtat gttgtttgct ttctttttat
     7561 gtaaaagaat aatagtggag tcatatttcg agtttagcaa actaacattg aaacgaatgc
     7621 taatgtttgg gggatggata acagtaagca atattataag tccgttaatg gcctattttg
     7681 accgatttat tgtttctaat caattaggtg cagcagtcgt tgccttttat acagctcctt
     7741 ctgaaattat tgcaaggtta ggtattgttc ccggtgcttt tgcccgcgct atttttcctc
     7801 gtttgagttg ttcaaatgat gtccacgata gaaaaaagaa caaaaaaata gtatcattac
     7861 ttcttttcct gataacagtt ccagtattta ttgtaggact tttggccagt aataaattta
     7921 tggttttgtg gatgggacct gaatttgcag gtacttcagc taatatattg gttattcttc
     7981 ttctcggttt tgttttcaat tcattagcac aggtcccttt tgctagtata cagtcacgtg
     8041 gttatgctaa aatcactgca tatatacata tggtggagct aatcccttat ttgatggctc
     8101 tgttttattt tattaataac tatggaatta ttggtgccgc gtatgcatgg agtataagag
     8161 tgactattga ttatatatta ttggcatttt ttgacagatg ctttgataag tagcataaga
     8221 aaattttaat aatcgctatc aaagaacgga ggaaatgacc atttatgtta tatgttctca
     8281 cttttgcgct cattacatca ttcgggcttt ttattgcact ttatctggtc aaatgtaact
     8341 ttacatcacc tctgtcttta cattgtttcg catggttttt cgttagtagc actggattgt
     8401 ttgcttatga tgagtttatt gattttcccg agataagctt ctatgcagta atgatttggt
     8461 acctgattgt atattttatt ttaataacag gtgagttaat atccttaaat ataaaaagtg
     8521 tgaactattt taaaaataag gaatatatat gtggaagata ttggatcata gtaataccat
     8581 tgtctgctta tacaatttac gaaatttata gagtgggaaa tactgggcct gcatcatttt
     8641 tccttaattt acgtctcgca aacattattg atgattacga aggtgaaaag ttcacattga
     8701 tgacggctat atatccagtc ttgatagcga tgttttccat cgtatgcata tcttgttcat
     8761 caaagaagaa taagtacgca ttatggctat ggtctattct attttgtatt ggcactatgg
     8821 gtaaatttgc tgtaataacc ccaattttaa ttttctatat aatccgtgag ttgacgggag
     8881 gcttaaataa aaagaggatg gtttttattg ttccaggtgt aatctctgct attcttttta
     8941 tgcatttcat acgaatgtct agtggagata gtactacaat aagttctgtt ctaggggtat
     9001 atatttactc gccactactt gcattgagta agttacctga actaaatata aatggtgaat
     9061 ctggtgaata tacattcaga tttttgattg caattctata taaagtaggc ctgtcctcaa
     9121 atgagccggt taaaactatt ttagattacg tcaacgtgcc cgttccaaca aatgttttta
     9181 cggtgatgca accattctac caagattatt ctttatttgg agtagcattt ggagcaatat
     9241 tttatgggat tatatattct tcaatatatc ttctggcaaa aaaaggaaat ccagttgccc
     9301 tgcttattta tgccgttctt gcaattagcc tatttacttc tttttttgca gaaactttaa
     9361 taactaacct tgcaggtaat ataaaggtag taatttgcat ataccttcta tggagattta
     9421 cagtaagatg caagataaaa ccgtaacgat attaatggca acttataatg gaagtgcttt
     9481 tatagagaac cagattcttt cattacagca acaaaaatat aaagattgga tactctatat
     9541 tcatgatgat ggttcctctg atgatacctt agatattata aagagaattc agcttacaga
     9601 acctcgtatt aatcttattg aggatgggct tacgagactt ggtgcaggga aaaattttct
     9661 ttcattagta aaatattcag ctacaaatta tactatattt tgcgatcaag atgatatttg
     9721 gctcgaaaac aaattaagcg agatgattgt tttcgcagat agtaaagggc tggctagtag
     9781 taagttacca tctatgattt atgcagatgg gtatgcattt gacgatagca caggtgagat
     9841 tgatttttgt ggtatatcac ataatcatgc tacgagattg aaagatttct tatttttcaa
     9901 tgctggctat caagggtgtt caatattatt taataaagca atggttgaca ttgcagcaaa
     9961 ttaccatggt tatgtccatt tacatgatga tgtcgtaagt ctgatcgccc attctttggg
    10021 gaatgtgtat tttttaccaa aaaaattgat gttatatcgc caacacttag gggcagtaac
    10081 tggccaaaag aagtttaata acagattcat ttcaatgctg acatccaaag ttaattatct
    10141 tttgtcaaga gagcattttt tagttaagag atctttttac gataattacc atcatctttt
    10201 aacggctgag attaaaaatg actttgaagt cttttttaaa ttttgccaaa caaaaaacaa
    10261 actttcacag ttagtgcttt tattgaagca tgattttcgc ttaaataaca gcagattaaa
    10321 gctattgtta aaatgcatag taagaaggac atttagtcaa tgatctccgt cttaacacct
    10381 acttataatc gtgcgtatac cttgaagcga ttatacgagt cgttaatttg tcaaacgact
    10441 aaatcctttg aatgggttgt ggttaatgat ggtagtaacg atgagactga gtcaataata
    10501 aaagagtttc agcaacaaaa tattattaaa attatttatt acaaacagga aaataaaggt
    10561 aaaactcagg ctcttaatgc aggtatacaa ttatgtgcag gaagtgatat tttaatcgtt
    10621 gatagcgatg atctattgac atcggatgct atagcttgca ttgaagctag tttgactcag
    10681 gagaagatat ataataaaaa aatatcgggg gtggcatttc gtaaagcata tctggatgaa
    10741 accataattg gtactgtttt tgatgatagt gttgatagtt tttgttatct ttctgcaact
    10801 gacgctgggc atcttttcaa aggcgatctt gcatattgct ttaagaaaga aatgctgcaa
    10861 atgtttcctt ttccatactt ttataacgaa aagtttgttc ctgaattata catttggaac
    10921 aagattacag atcacgcatt agtaaaattt cataaaaaaa aagcagtata cctatgtgag
    10981 tatctcgaag atgggttatc taaaaacttc aaaacacaat tattaaaaaa tcccaaaggg
    11041 tttagtatct attatattga tcagtttaag cgtgaaacca actacattcg aaaattaaaa
    11101 atgttgattc gttattttca gtgtaaatta tatgagctaa aaaaatgaat atagtgtttg
    11161 tgattactgg attgggactt gggggggctg aaaagcaagt atgcttattg gctgatcgac
    11221 tggctgaggc agagcatcaa atatcgatag tgtcccttac aggagaatgt gttgttaagc
    11281 cagataataa gcatattgaa atttaccacc ttaatatgga taaaagccta ataagtttct
    11341 ttttaggtgt tataaaatta cgtaatatta tttctactat taagcctgat attgtgcata
    11401 gccatatgtt ccatgcaaat atcatgtcta gattaagtaa gttactattg ccttattccc
    11461 ataagctcat atgtacagca catagcagat atgagggagg gaggcttcgt atgctttgtt
    11521 atcgtttaac agattatttc agtgatataa atacaaacgt tagtaaagag gcgctcgatg
    11581 aatatgttaa taataaatat ttctcagcga ctaaatctat tgttgtttat aatggcgttg
    11641 atacagaaaa atttaatttc agtattgata atcgtattta tataagagag caattgtcta
    11701 ttaataacca tgataggttg attctcagtg ttggcagatt aaaccctgct aaagattatc
    11761 ctaatctgct agcagcattc atgcttttac ctgagcacta taagcttgtt atcattggtg
    11821 agggagacgt tcgttcacag attgaacaga taattaaaga tcacaagtta gggacgcgtg
    11881 ttcagttact tggtagtgta aataatgtca atgattatta ttctgcttgt gatttatttg
    11941 tcttatcttc ggcttgggaa ggttttagct tagttgttat cgaggccatg gcatgtcaac
    12001 gcatcgctgt atgtactgat gcaggtggag taaaagaagc ttttactgat cgtcattaca
    12061 ttgtaccaac ttcaaatgcc gcagctttag ctcgcaaaat tattgaagtt gatatgttaa
    12121 ctattgatcg taaaaatgaa atacaaaatg ataataggaa taatgttgtt aacaagtttt
    12181 caattaatgc tattgttaat cattggttaa caatctataa aaatataact atgcagtaga
    12241 taaatctatt acataatgat gaattaaaaa caatattaat ttttagctgt tttttataat
    12301 acctagttca atatggatta aattattttg ttttttaatt tgtaatctgg aataggttat
    12361 tatatttact agattgaatg tagttcaatg gatagattat cacgttaaca tttaattgaa
    12421 gtataagttg tgtggcgttg tgttgcttta aattcttaat aaataattaa ggttggtgat
    12481 taatgactat tttagtaacg ggcggtgctg gctatatagg ttcgcataca gtggtgagac
    12541 tgcttgaaaa gggtaaagaa attgttattc ttgatgattt tactaattca tttcctgaaa
    12601 cattgaatag aataaaaata attaccggtg ttaaaccttt tttttacgaa ggttctgtcc
    12661 ttgataggaa tttattgaaa aaaatctttg tcgaaaataa catcaccgat gttattcatt
    12721 ttgcagggct caaatcagtt ggtgaatccg tatcgtcccc tcttaagtat tatgaagtca
    12781 atatagcagg aagtttgcat ctagttgaag agatgattac gcacaatata agcaatttta
    12841 tttttagctc ttctgcaaca gtatatggtg aaccagaaac tattccattg acggagtcct
    12901 ctcgcattgg tggcactaca aacccttatg gtacatctaa gcttatggtt gagaaaatac
    12961 ttgaggatgt tactcgttct aatcctgagt ttagaaccac aattttacga tattttaatc
    13021 ccgttggtgc tcatccttct ggtgatatgg gcgaagatcc gaatggtatt ccaaataatc
    13081 tcatgcctta tatctgtcag gttgctattg gtaagtataa gcaagtttca gtatacggaa
    13141 gcgattatcc aacaaaggat ggtactggag tccgtgactt tatacatgta atggatcttg
    13201 ctgaaggtca tgttgctgct ttagagcaca gaaataaggg accaaatcat aaagtttaca
    13261 acttgggcac aggcactggt tattctgttt tggaactcct gacagctttt gaaagagtaa
    13321 cttctcgtaa agtaccttac gttttaagtg aaagacgccc tggagatatc gccgaatgtt
    13381 ggtctaatcc ttcgaaggcg tatgcggaac ttggatggaa agcgaagcgc ggactggaag
    13441 acatggttcg agatgcctgg aattggcaac aaaagaatcc aaacggttat aaaaaagaat
    13501 gaatgatcaa agaaattttt gtcaactgca aaaattaccg aatttatgta tcctgagtta
    13561 acatagcact aacattgaat tgcgttatgt ttcccagtat cacctctgac aggagtaaac
    13621 aatgtcaaag caacagatcg gcgtcgtcgg tatggcagtg atggggcgca accttgcgct
    13681 caacatcgaa agccgtggtt ataccgtctc tattttcaac cgttcccgtg aaaagacgga
    13741 agaagtgatt gccgaaaatc cgggcaagaa actggttcct tactatacgg tgaaagagtt
    13801 tgttgaatct ctggaaacgc ctcgtcgcat cctgttaatg gtgaaagcag gtgcaggcac
    13861 ggatgctgct attgattctc tcaagccata cctcgataaa ggcgacatca tcattgatgg
    13921 cggtaatacc ttcttccagg acaccattcg tcgtaaccgt gagctttctg cagaaggctt
    13981 taacttcatc ggtaccggtg tttccggcgg tgaagaaggt gcgctgaaag gtccttccat
    14041 tatgcctggc ggacagaaag aagcctatga actggttgcg ccgatcctga ccaagatcgc
    14101 cgccgttgct gaagatggcg aaccgtgcgt tacatatatt ggtgccgatg gcgcgggtca
    14161 ctatgtaaaa atggttcaca acggtattga atacggtgat atgcaactga ttgctgaagc
    14221 ctattctctc ctgaaaggcg gcctgaatct ctctaacgaa gaactggcac agacctttac
    14281 cgagtggaat aacggtgaac tgagcagcta cctgatcgac atcaccaaag acatcttcac
    14341 taaaaaagat gaagacggta actacctggt tgatgtgatt ctggatgaag cagcaaacaa
    14401 aggtaccggt aaatggacca gccagagtgc gctggatctc ggcgaaccgc tgtcgctgat
    14461 taccgagtct gtgtttgcac gttatatctc ttctctgaaa gatcagcgtg ttgccgcatc
    14521 taaagttctc tctggcccgc aagcacagcc agcaggcgag aaggctgagt tcatcgaaaa
    14581 agttcgccgt gcgctgtatc tgggtaaaat cgtttcttac gctcagggct tctctcagct
    14641 gcgtgctgcg tctgaagagt ataactggga tctgaactac ggcgaaatcg cgaagatttt
    14701 ccgtgctggc tgcatcatcc gtgcgcagtt cctgcagaaa atcaccgatg cttatgccga
    14761 aaatccgcag atcgctaacc tgctgctggc tccgtacttc aagcaaattg ccgatgacta
    14821 ccagcaggcg ctgcgtgatg tcgttgctta tgcagtacag aacggtatcc cggttccgac
    14881 cttctctgct tcggttgcct attacgatag ctaccgtgcc gctgttctgc ctgcgaacct
    14941 gatccaggca cagcgtgact atttcggtgc gcatacttat aagcgcattg ataaagaagg
    15001 tgtgttccat actgaatggc tggattaatc tgatttaacc aacaataaaa ttgaggcccg
    15061 gcgtatattg caccgggctt ttttttgcca attatcttat agactaaatt tcactgctta
    15121 atattaactt aataaatatc agctattctt ataaagaaaa tctgaatttt tttcgttgcg
    15181 ttgaccatcg aacaacgtag cgttaaaact tttagctctt atcaggatgc taaaaacatc
    15241 atgattcaca gttaagttaa ttctgagagc atgaaatgaa aatcaccatt tccggtactg
    15301 gctatgtagg cttgtcaaac gggcttctaa tcgcacaaaa tcatgaggtt gtggcattag
    15361 atattttaca gtcacgcgtt gctatgctga atgatcggat atctcctatt gttgataagg
    15421 aaattcagca gtttttgcaa tcagataaaa tacactttaa tgccacatta gataaaaatg
    15481 aagcctaccg tgatgctgat tatgtcatca tcgccactcc aacagactat gatcctaaaa
    15541 ctaattattt caatacatct agtgtagaat cagtaattaa agacgtagta gagataaatc
    15601 cttatgcggt tatggtcatc aaatctacgg ttcccgttgg ttttaccgca gcgatgcata
    15661 agaaatatcg tactgaaaat attattttct cccccgaatt cctccgcgaa ggtaaagccc
    15721 tttacgataa ccttcatccg tcacgtattg tcatcggtga gcgttcagaa cgcgcagaac
    15781 gttttgcggc gttattacag gaaggcgcga ttaagcaaaa tatcccaacc ctgtttaccg
    15841 actccactga agcagaagcg attaaacttt tcgctaatac ctatctggcg atgcgcgtag
    15901 catactttaa tgaactggat agctatgcag aaagtttagg gctgaatact cgccaaatta
    15961 tcgaaggcgt ttgtctcgat ccgcgtattg gtaaccatta caacaacccg tcgtttggtt
    16021 atggtggcta ttgtttgccg aaagatacca agcagttact ggcgaactac cagtctgtgc
    16081 cgaataacct gatttcggca attgtcgatg caaaccgcac gcgtaaagat tttattgccg
    16141 atgccatttt gtcacgcaaa ccgcaagtgg tgggtattta tcgtctgatt atgaagagcg
    16201 ggtcagataa cttccgtgcg tcttccattc aggggattat gaaacgtatc aaagcgaaag
    16261 gcgttgaagt gattatctac gagccggtga tgaaagaaga ctcattcttc aactctcgtc
    16321 tggaacgtga tctcgccacc ttcaaacaac aagccgacgt cattatttcc aaccgtatgg
    16381 cagaagagct taaggatgtg gcagacaaag tctacacccg agatctcttc ggcagcgact
    16441 aatcttctgt aatcagggcg atttttgccc tgattgtctt ttgttttctt tgtgataatt
    16501 cattgttttt atcatttatc ctatagtatt tatggcgatt atcgctaaac tatggcgact
    16561 taaaattatt tcgtccgtta gggtaatgat gagagtagaa aataataatg tttctgggca
    16621 aaaccatgat ccggaacaga ttgatttgat tgatttactg gtccaactat ggcgcggcaa
    16681 gatgactatc atcatttctg tcattgtggc tattgccctg gctatagggt atctgaccgt
    16741 tgccaaagaa aagtggactt caacagctat cgttactcaa cctgatgtgg gacaaatcgc
    16801 tggttatacc aacgcgatga atgtgattta cggtccggca gtaccgaaag tctccgacat
    16861 tcaggcttca cttatcggac gttacagcac tgcattttca gcattagcgg aaacgctgga
    16921 taaccaggaa gaagcagaaa agctgaccat tgagcctacc gttaaaaatc agtcattacc
    16981 tttagcggtt tcttatgtcg gtgaaacacc tgaaggtgcg cagaagcagc tggcgaagta
    17041 tatccagcaa gttgacgacc aggtaaatga agaactggaa caagacctga aagacaacat
    17101 cgcgctgcga atgaaaaact tgcaggattc tctgaagacg caggaagtgg tcgctcaaga
    17161 acagaaagat ctgcgtatcc gtcagattca ggaagcgttg cagtatgcga atcaggcgca
    17221 ggtgacaaag ccgcagattc aacagacaca ggacgtaacc caggatacta tgttcctttt
    17281 ggggagcgaa gcgctggagt cgatgattaa gcacgaggcg actcgtccgt tggtgttctc
    17341 accaaactac tatcagactc gtcaaaacct gctggatatt gaaaacttaa aggctgatga
    17401 tcttgatatt catgcttacc gctatgtaat gaaaccgacg ttacctattc gtcgcgatag
    17461 cccgaagaaa gcaattacct tgattctggc tgtgctgctg ggcggcatgg ttggcgcggg
    17521 gattgtgctt gggcgtaacg cgctgcgtaa ttacaacgcg aaataatatt attgtgcatt
    17581 taagagaaac gggcagggtg gtgacaccat gcccgttttt tttgccggat gcgatgctgg
    17641 cgcatcttat ccggcctacg tgtgttgaga taatgtgtag gcacgataag cttgcgcatc
    17701 gggcaatggc tccgggtgtg acaacaacat cacacctgct cagcccgcaa ctcactgatg
    17761 ccgtttacgc aggttctcaa ttaccgtcgt taaatccaga tcctgatcct gcaacagcac
    17821 cagcaggtga tacatcaaat cagacgcctc gttggtcagc tcaaagcggt catgtaccgt
    17881 tgctgccagt gcggtttcca cgccttcttc gcccactttc tgtgcaatgc gtttggtgcc
    17941 gctggcatac agtttggctg tgtaagaggt ttccgggtcg gcagatttgc gttcggcgag
    18001 cagttgttcc agttgataca ggaacagcca ttggtgagcg gtgtcgccga agcagctgct
    18061 ggtgcctttg tggcaggttg gtccgatagg attcgccaat accagtagcg tgtcgttgtc
    18121 gcagtccggc gcaatactca ccacattgag gaaattgccc gacgtttcgc ctttggtcca
    18181 cagtcgctgt ttagtgcgcg agaagaaggt gactttgccg ctttcgatgg ttttatctaa
    18241 ggcttccggg ttcatatagc ccagcattaa cacttcaccg gataccgcgt gttgcacaat
    18301 caccggcata agtccgtcga ttttttccca gtccagttcg cgacgttgtt gttctgttaa
    18361 catatcctga tctccacgcc ctgtgttgcc aggtacgctt ttaattcacc aatattgatt
    18421 atttgtttgt ggaatacgga agccgccagc gcgccgtcaa cgtcggcatc gcggaaggct
    18481 tcgaggaagt gttccatggt gcccgcgcca ccggaggcaa tcagcgggac gtggcaaact
    18541 tcacgtactt ttttcagctg ctcgaggtcg taaccgttac gtacgccgtc ctgattcatc
    18601 atgttgagga cgatttcacc ggccccgcgt ttttgtactt cctgtaccca gtcgagcgtt
    18661 tcccactgag tgacgcgggt gcggctttca ttgccggtat attgattcac atgatattta
    18721 ccggtttcgg cgtcgtacca ggtatcaatg ccgaccacaa tacactgcac gccaaagcga
    18781 tccgccaggc gagtaattaa cgtcgggtcc gccagcgcag gcgagttgat ggagatttta
    18841 tccgcgccaa aggaaagaat tttcgcggca tcttccagag act
//
