LOCUS       AB812062               18384 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli genes for O-antigen biosynthetic locus, partial
            sequence, strain: 1624-56.
ACCESSION   AB812062
VERSION     AB812062.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 18384)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..18384
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="1624-56"
                     /db_xref="taxon:562"
                     /note="serogroup:O144"
     gene            <1..906
                     /gene="wcaM"
     CDS             <1..906
                     /gene="wcaM"
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis protein"
                     /protein_id="BAQ01741.1"
                     /translation="NYAILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDRDILI
                     SDHVIERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVE
                     NGKHFVIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVI
                     KGKYLSIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNK
                     PQHLFMRNIKVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNERGQSS
                     VDIDRVNHHIVNVENINFRLPERRE"
     gene            1081..1974
                     /gene="galF"
     CDS             1081..1974
                     /gene="galF"
                     /note="O144_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ01742.1"
                     /translation="MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNV
                     RQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRS
                     QVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLS
                     ADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFRKGIEKLLNE"
     gene            2320..3528
                     /gene="wzy"
     CDS             2320..3528
                     /gene="wzy"
                     /note="O144_02"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAQ01743.1"
                     /translation="MNDRINMIRNENAIIIMATILAVIFLCCVSLSPLLGFYIPLMFL
                     CIVCGNSKYIRMVLILFSIYSASFFVASRNIFDANASDFDVYYDVYQIVNNGGTILYK
                     DFSAGFEFFLPLFFKMISFILGDASPQIVLAVTVFAQLFLLYIWLEWDGFKNVNPEDR
                     NLCAASTFGLLFIYMFSQILRQGFSSVFCLFAISFFLRKERLSFIIFYLLAISSHLTA
                     IIIVPMFIIFMKNKKISMLICLGMFAFSGVFSLLLPFIVAHNLFGEMSYKFAFYTFTS
                     LAGYDLSSYFKFLVITVIAGYFFFDNKNKYLKPLIYYGGLAYIALLPIPLASDRMLMV
                     LAALLPGYILFFSFYKIKNIYKIILILFFVLKVMTYGPFYDHKKDYDNPMQYWYTYPW
                     INDTPFYYIH"
     CDS             3583..4671
                     /note="O144_03"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf4"
                     /product="glycosyltransferase"
                     /protein_id="BAQ01744.1"
                     /translation="MKKIAILTTNIGNSGGTERVVSFVANNFSKKNDVTVYSMVKTSI
                     STFYELDSKISIRYLNLYQYEHEKRVLFKTIKKVWNTISFFYKVKNIDADIIIGTSKS
                     INIYLSLLSFFFKKKIIGCEHFAHNAPMSKFIKTIRLVAYKRLDRLIVLTLFDYNYYK
                     SKGIKTEIIPNAIPFQINQRPEHRAKIILAVGRHSIQKRFDLLLRIWLKAKLYEHGWQ
                     LKIIGDGELFDRNKSLAIDLGIAESVFFEPPTKDIVDEYLNASFFVMTSEYEALPMVL
                     IESMYCGLPCIAFDCDTGPRDIIEDNVDGFIVPFGNIELFSQKMIWLSNNDVILKEMS
                     TSAVLNISRFSAQTIYEKWNGLIRDIYE"
     CDS             4695..5807
                     /note="O144_04"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf5"
                     /product="glycosyltransferase"
                     /protein_id="BAQ01745.1"
                     /translation="MNKIKVLQMGKFYPPSFGGIEQVVYDITKGINSLSSKYCCDVLC
                     FNHDTRKGSKTDYSDGAEIYRMNTIGVISSAPISLMYFFKFIKIKGEYDIIHLHAPNP
                     IATIAALFARNKKIIIHWHSDIVKQKRLLRLFLPVQKQMLNRASKIIVTSDNYGRCSE
                     QLFGFERKIMPIPIGIPSDKTLTPKEYVPKNKKIIFSLGRLIYYKGFEYLIEAAKYLP
                     ENYMVIIGGTGSLYSELQKKIDDNRLNNKVRLVGRIPMEELQSYYESADLFCMPSIEK
                     SEAFGVVQLEAMKHGVPVVSTRIPGSGVSWVNLNGVSGLTVPVKNSQALSEAFINILE
                     NESLYKHLSNGALRRYNENFTSDKMCRKIIELYDEL"
     CDS             5837..6907
                     /note="O144_05"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf6"
                     /product="glycosyltransferase"
                     /protein_id="BAQ01746.1"
                     /translation="MKKILVDCRLINNSGIGVYIKSMLEELREYSDIHVSILVMYQEN
                     KVEELCDLINGDVIYTRISRFNPLNLFIFNKILSGFDFYFVPFLSILPVRIFSGKVKI
                     ISTVHDLCPIKVKKAFDWRVIIVYYIIMYLQLKFSNSIIAISNFTKTEIIDIYGKQYS
                     NKITVIYNAARIIPSGQSLIKECDFKSEIYGICVGNIKPHKNITPLISYWKKNKIKVK
                     LLFVGESSGFYTSDISSMLLTNEYVSFTGFITDEELHEYYKGASFFIYPSLYEGFGLP
                     LLEAMSYKLKIFASDIPVFHEIANDSIEYFSPENFSGLKEKIEKFIASSREEKISYNY
                     ESILNKYSWRDSVKLFVHDLLI"
     gene            6946..8385
                     /gene="manC"
     CDS             6946..8385
                     /gene="manC"
                     /note="O144_06"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="BAQ01747.1"
                     /translation="MKEKNKIYPVIVAGGTGSRLWPLSRELYPKQFLCLQGKLTMLQT
                     TLCRLNDLPCEEPIVICNEQHRFIVAEQLQQINKLTKNIILEPEGRNTAPAITLAALA
                     ALMNNLGEDPMVLVLAADHIIEDEKKFQETVREALFFAKKDKLVTFGIVPDHPETGYG
                     YIKRGNAIDNENSFRAYSVSEFIEKPNLVTAKKYVSMDSYYWNSGMFLFRANRYIEEL
                     EKFRPDILSACRQAMCHINNDLDFIRIDDEAFLACPEESIDYAVMEHTADAIVVPLDA
                     GWNDVGSWRALWEISQRNDEGNSVYGDVISYMTNNSYLYAESGLVTTVGVKDLIVVQT
                     KDAVLVADRHAVQDVKKVVEQLKLKGRQEHHMHREVYRPWGKYDSIDSGKRYQVKRIT
                     VKPGEGLSLQMHHHCSEHWIVVAGTAKITLNNKSYLVSENESIYIPLGAKHSLENPGK
                     IPLELIEVRTGSYLKEDDVIRLKDRYGRV"
     gene            8412..9806
                     /gene="manB"
     CDS             8412..9806
                     /gene="manB"
                     /note="O144_07"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="BAQ01748.1"
                     /translation="MKTLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLG
                     GDVRLTSETLKLALAEGLQDAGVDVLDIGMSGTEEIYFATFHLDVDGGIEITASHNPI
                     DYNGMKLVREGARPISGDTGLRDIQRLVEANNFSPINESRRGSYKPINLRNAYVNHLL
                     SYINVKNLTPLKLVINSGNGAAGPVVDAIEAHFKALGAPVELIKLHNTPDGTFPNGIP
                     NPLLPECRDDTSNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLE
                     KNPGAKIIHDPRLYWNTVDVVTAAGGTPIMSKTGHAFIKERMRKEDAIYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVAELVCLKGKMLGELVRDRMAAFPASGEINTKLAQPAEAINR
                     VEQHFSSEALAVDRTDGISMTFADWRFNLRTSNTEPVVRLNVESRGDVRMMERNTKIV
                     FSLLNDNTIICNKG"
     CDS             9817..10836
                     /note="O144_08"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf9"
                     /product="putative pyruvyl transferase"
                     /protein_id="BAQ01749.1"
                     /translation="MKLYYYKSPTGNFGDDLNAWLWEELLPGYFKYENGIIFSGIGTI
                     ISADMPTSSKTVIFGSGVGYGYPPMNFGDNRWDVRFVRGPLSAKVLSLPANKYITDSA
                     ILVSKIEGFEPLPENERSGIIFVPHHHALHTGQWHEVCKSVGIEFIDPTQDSKYVIQK
                     IRKSKLVLADAMHAAIIADSLRVPWIPLVTSNQINTFKWIDWTLSVKLEYSPSYIGPS
                     SMRECLRNKFLHLYGESFYIKSLNADDSINCFYKQRDILSNKWWPIYSKIIRRCVYTA
                     PNLLLKKIEQFSSPRWDEKYISLAKKKILDAMKRAPMLSSDDVYQSNLNKILNEVECV
                     RKMYK"
     gene            10854..12371
                     /gene="wzx"
     CDS             10854..12371
                     /gene="wzx"
                     /note="O144_09"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAQ01750.1"
                     /translation="MSSIKKIVLNSSALYIRMIFVMLVNLLATRFLMANFGIDGFGLY
                     NVISSIVVLGAFITGILTVSSQRFISSGLAKAGHVGANDYLNAIFAVHILCFISIIII
                     LEIFGYIYINGFLKQDVLPINDVYYIYHITVAGFSFSIFISFLNSICIAEENMSAYAR
                     FSILDATLKLLIAYSTLFVHKNTMIVYALAMLFEVIIMVFVMVIFIHRRYPYYKINNN
                     YDFMKIKEVFSFVIWSLWGGVATVLSNQGINLLLNYNFGVAINAARGVSMQINSAYLQ
                     IVNNFQFAINPQLVKSYASNDISRFERLFFLGSKVSILFSTIIFFILYVNINYVLSLW
                     LINYSEDMVSFSKLIIIDAYITSFSTAIILAIQASGRIKIYQSIVGVILLLNLPLSYA
                     ALKYWHEPQLVFVVSITLSILSLIFRMLFLQKIVKIKFRSFLFVIIFPNICVFAIVSL
                     VVNYNISLALTFQQFIINSVLITLLVIFLFIFISLNSMERKMLLNNFLKITKGFK"
     CDS             12368..13309
                     /note="O144_10"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf11"
                     /product="glycosyltransferase"
                     /protein_id="BAQ01751.1"
                     /translation="MKLSFVIPLFNKEKNIIATLKSIISACEENNINDSYEIIVVDDG
                     STDSSGKVVREFIQLKNSCVRYYFQNNSGPSMARNRGVSESTGEYILFVDADDLLLPA
                     YIAYILYCTKHYHSYPVYCAGYSKVNSSVDIKEEKIKFDCSQITIVTDFFKKWKETKF
                     FYTSSICVKRSFWIQKNVYFPVEHFTGEDQYAWFCLAQHCHFVYLPQQVVLYKQGVVG
                     QLSSSRPVTIEIHVQKLLELEKNIILKRDVSKLIDKEFCYVISNNFVAYQRFLGVKIL
                     QNRLRVLLNFHCVLKLIFSFIAPRFYNYLRNRRDINT"
     gene            13404..14810
                     /gene="gnd"
     CDS             13404..14810
                     /gene="gnd"
                     /note="O144_11"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ01752.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            15059..16225
                     /gene="ugd"
     CDS             15059..16225
                     /gene="ugd"
                     /note="O144_12"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ01753.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDKINFNATLDKNEAYRDAGYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            16315..17358
                     /gene="wzz"
     CDS             16315..17358
                     /gene="wzz"
                     /note="O144_13"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ01754.1"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLID
                     LLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVI
                     YGSAVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQSLPLAVSYVG
                     ETPEGAQKQLAQYIQQVDDQVNEELEKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLR
                     IRQIQEALQYANQAQVTKPQVQQTEDVTQDTLFLLGSEALESMIKHEATRPLVFSPNY
                     YQTRQNLLDIESLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGI
                     VLGRNALRNYNAK"
     gene            complement(17456..18055)
                     /gene="hisI"
     CDS             complement(17456..18055)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ01755.1"
                     /translation="MLTEQLDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDKTTES
                     GKVTFFSRTKQRLWTKGETSGNFLNVVSIAPDCDNDTLLVLANPIGPTCHKGTSSCFG
                     DTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALAATVH
                     DRVELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ"
BASE COUNT     5591 a   3189 c   3858 g   5746 t
ORIGIN
        1 aattacgcca tcttacgcca gggatttcat aatcagatta tcggtgccaa catcaccaat
       61 tgtaagttca gtgatttaca gggcgacgcc atcgaatgga atgtggcgat taacgaccgt
      121 gatattttga tctccgacca tgtcatcgag cgcatcaact gtaccaacgg caaaatcaac
      181 tggggaatcg gcataggcct tgcgggaagt acctacgata ataactaccc ggaagaccag
      241 gcagtgaaaa actttgtcgt ggcgaatatc acgggatcgg attgtcggca gttgatccat
      301 gttgaaaatg gtaaacattt tgttatccgt aatatcaaag cccgcaatat cacgccggat
      361 ttcagtaaga aagcaggtat tgataacgcc acagtcgcta tttacggttg tgacaatttc
      421 gtgattgata atattgaaat gattaatagc gccgggatgt taatcggcta tggggtaatt
      481 aaaggcaaat atctctcgat accacaaaat ttccgagtga ataatattca actggataac
      541 acccaccttg cttacaaatt gcgcggcatc caaatctccg ccgggaatgc cgtctccttt
      601 gtggcgctga ctaacattga gatgaagcgt gcttcgcttg agctacacaa taaaccgcaa
      661 catcttttta tgcgtaatat caaggtgatg caggaatcct cagttggacc cgcattgagc
      721 atgaacttcg acatgcgcaa agacgttcgc ggcgtgttta tggcgaaaaa agaaacacta
      781 ctatctcttg caaatgttca tgcggtgaat gaaagagggc aaagctccgt cgatatcgac
      841 agggttaatc accatattgt taatgtggaa aatattaact ttagattgcc ggaacggaga
      901 gagtagattt gcgaccattc ctggaaaaat ggagccatac ttaggaacaa tgctactgca
      961 atccacaacg aagcggcgta acatcacaag taattcagta atcaattcag ggtaattgat
     1021 gctggcgaaa aaaatcgaac aagctataat tcagcaacca ttttacaggt ggatgaaata
     1081 atgacgaatt taaaagcagt tattcctgta gcgggtcttg ggatgcatat gttgcctgcc
     1141 actaaggcga ttcccaaaga gatgctaccg atcgtcgaca agccaatgat tcagtacatt
     1201 gttgacgaga tcgtggctgc agggatcaaa gaaatcctcc tggtaactca tgcgtccaag
     1261 aacgcagtcg aaaaccactt cgacacctcg tatgaattag aatctctcct tgagcagcgc
     1321 gtgaagcgtc aactgctggc ggaagttcag tccatctgcc cgccgggcgt gactattatg
     1381 aacgtgcgtc agggcgaacc tttaggttta ggccactcca ttttatgtgc acgacccgcc
     1441 attggtgaca atccatttgt cgtggtactg ccagacgttg tgattgacga cgccagcgcc
     1501 gacccgctgc gctacaacct tgctgccatg attgcgcgct tcaacgaaac gggccgcagc
     1561 caggtgctgg caaaacgtat gccaggtgac ctctctgaat actccgtcat tcagaccaaa
     1621 gaaccacttg atcgtgaagg taaagtcagc cgcattgttg aatttatcga aaaaccggat
     1681 cagccgcaga cgctggactc agacatcatg gccgttggtc gctatgtgct ttctgccgat
     1741 atttggccgg aactagaacg cactcagcct ggtgcatggg gacgtatcca actgacagat
     1801 gctattgccg aactggcgaa aaaacagtcc gttgatgcca tgctgatgac aggtgacagc
     1861 tacgactgcg gtaaaaaaat gggttatatg caggcatttg tgaagtatgg actacgcaac
     1921 ctgaaagaag gggcgaagtt ccgtaaaggg attgagaagc tgttaaacga ataatgaaaa
     1981 tctgaccgga tgtaacggtt gataagaaaa ttataacggc agtgaagatt cgtggcgaaa
     2041 gtaatatgtt gcgaatattc ctgccgttgt tttatataaa caatcagaat aacaacgagt
     2101 tagcaatagg attttagtca aagttttcaa ggattttcct tgtttccaga gcggattggt
     2161 aagacaatta gcgtttgaat ttttcgggtt tagcgcgagt gggtaacgct cgtcacatcg
     2221 taggcatgca tgcagtgctc tggtagctgt aaagccaggg gcggtagcgt tcgttaatat
     2281 agataccaat atataaaatt acatgtggct aaatgttaga tgaatgatag aataaatatg
     2341 ataagaaatg aaaatgccat aattattatg gcgacgatat tagcggttat ttttttgtgt
     2401 tgtgtgtcac tgtctccatt attgggtttt tatatcccgt taatgttttt atgtatagtg
     2461 tgcggtaatt ccaaatacat cagaatggtt ttaatcttat tttcaatata ttctgcttca
     2521 ttttttgttg cctcgcgaaa tatatttgat gcgaatgcaa gtgattttga tgtttactat
     2581 gatgtttatc agatagtgaa taacgggggg actatattat acaaggactt ttctgctggg
     2641 tttgaatttt tcttgccatt attctttaaa atgatttctt ttattttggg agatgcaagc
     2701 ccgcagattg tgcttgcagt tacagttttt gcacaattgt ttttgctcta tatatggttg
     2761 gaatgggatg gatttaaaaa tgtaaatcca gaagaccgta atttatgtgc tgcatcaaca
     2821 tttggtttac tctttattta tatgttttct cagatcttga gacaaggatt ctcgagtgtc
     2881 ttttgtttgt ttgcaatatc attttttctt cgtaaagaaa gattatcatt tattatattt
     2941 tatctgttag ctatatcatc tcatttaaca gctataatca ttgtgcctat gtttattatt
     3001 tttatgaaaa ataaaaaaat aagcatgtta atatgtttgg ggatgtttgc tttctcaggc
     3061 gtatttagtt tgttattgcc atttattgtt gctcataatt tatttggcga aatgtcatat
     3121 aaatttgcat tttacacatt tacatcactt gctggttatg acctatctag ttactttaag
     3181 tttttagtta ttactgttat cgcaggttat ttcttttttg ataataagaa taaatactta
     3241 aagccgttaa tatattatgg aggattggct tacattgcat tattaccaat tccattggct
     3301 tctgatagaa tgctaatggt tttagctgca ctgttgccgg gatatatact attttttagt
     3361 ttttataaaa tcaaaaatat ttacaaaata atattgattt tgttttttgt gttaaaggta
     3421 atgacttatg gtccatttta tgatcataaa aaagattatg ataacccaat gcaatactgg
     3481 tatacgtatc catggataaa tgacactcca ttttattata tacattaaaa aacgaaaaag
     3541 ttatttgttg gcaatgtttt ttgagaaaag attacattaa atatgaagaa aattgcaatt
     3601 cttactacta atattggtaa cagtggtggg actgaaagag tcgtatcatt tgttgccaat
     3661 aatttttcca agaagaatga tgttactgtt tatagtatgg taaaaacatc tatttctact
     3721 ttttatgaat tagatagtaa aatatctatt cgatatttaa atttatatca atatgagcat
     3781 gaaaaaagag tgctatttaa aactataaaa aaggtatgga atacaatttc atttttttat
     3841 aaggtgaaaa atatagatgc agatattatt ataggtacaa gtaaaagtat taatatatat
     3901 ctatcactac taagtttttt tttcaaaaag aaaatcatag gatgtgagca ttttgctcat
     3961 aatgccccta tgtctaaatt tattaagaca atcagacttg ttgcatataa acggttagat
     4021 cgtttaatag tcttaacatt atttgattac aattattata aaagtaaggg aataaaaacc
     4081 gaaattatac cgaatgcaat accttttcaa ataaatcaga gacccgaaca tagggctaaa
     4141 ataatcttgg ctgttggacg acatagcata caaaagcgat ttgatctact ccttagaatt
     4201 tggctgaagg caaaattata tgaacatgga tggcagctta aaataatcgg tgatggagag
     4261 cttttcgaca gaaataagag cttagctatt gatctaggaa ttgcagagtc agttttcttt
     4321 gagccgccta cgaaggatat agtcgatgaa tatctaaatg cctcattttt tgtcatgaca
     4381 tcagaatatg aagctcttcc tatggtacta atagaatcta tgtattgtgg tttaccctgt
     4441 atagccttcg actgtgatac agggccaagg gatataatag aggataatgt tgatggcttt
     4501 attgttccat ttggcaatat tgagcttttt tcccaaaaaa tgatatggtt atcaaataat
     4561 gatgtaattt taaaagaaat gagcaccagt gctgttttaa atatttcaag attttccgct
     4621 caaactatat atgaaaagtg gaatggtttg attcgagata tttatgaata atatcattat
     4681 ggattgagtt aactatgaat aaaattaaag tattacaaat ggggaagttt taccctcctt
     4741 catttggagg gattgaacaa gttgtttatg atataactaa agggattaat agcttatctt
     4801 caaaatactg ctgtgatgtc ttatgtttta atcatgatac aagaaaggga agcaaaactg
     4861 attatagtga cggagctgaa atatatagaa tgaatactat cggagttata tcctcagctc
     4921 caatatcact catgtatttt tttaaattta taaaaattaa aggggaatat gatattattc
     4981 acttacatgc acctaatccc attgcaacta ttgctgcact ttttgcaaga aataaaaaga
     5041 ttataatcca ctggcatagt gatatagtaa aacaaaaaag attattgagg ttatttttgc
     5101 ctgtccagaa gcaaatgctt aaccgtgcat cgaaaataat agtaacaagt gataactatg
     5161 gaaggtgctc agaacaatta tttggatttg agcgaaaaat tatgccaata cctattggca
     5221 taccatcgga taaaacttta actccaaaag aatatgtgcc aaaaaataaa aaaattattt
     5281 tttctctggg gcgcctcatt tactataaag gttttgagta tttaattgaa gcagcaaaat
     5341 atttgccaga aaattacatg gtaattattg gtggtacagg gtcgttatat tcagaactgc
     5401 aaaagaaaat agatgataat aggttgaaca ataaagttcg attggttggg cgaatcccca
     5461 tggaggaatt acaaagttat tatgagagcg cagatttgtt ttgtatgcct tctattgaaa
     5521 aatcagaagc ttttggagtt gttcagttag aagcaatgaa acatggagtt ccagttgtat
     5581 caactcggat accgggatcg ggggttagct gggtaaattt aaatggagta agcggattaa
     5641 cagttccagt taaaaatagt caagcgttat cggaagcttt cataaatatt ttagaaaacg
     5701 aatcccttta taaacattta tcgaatggag ctttaaggag atataatgag aatttcacat
     5761 cagataaaat gtgtagaaaa ataattgaac tttatgatga actatagatt tatctttgcg
     5821 ataagattat taaataatga aaaaaatact tgttgattgt cggttaataa ataactctgg
     5881 tattggtgtt tatattaaat caatgttaga agagttaaga gaatatagtg atattcatgt
     5941 gtctatatta gttatgtatc aagaaaacaa agtagaggaa ttatgtgatt tgataaatgg
     6001 agatgtaata tatacaagaa tatcgcgatt taatcctctt aatttattta ttttcaacaa
     6061 aatattatct ggatttgatt tttattttgt gcctttttta agtatattgc ctgtaagaat
     6121 attttctggc aaagtgaaaa taatatctac ggtccatgat ttgtgtccaa ttaaagtaaa
     6181 aaaagcattt gattggaggg ttataattgt gtactacata attatgtatt tacagttaaa
     6241 gttctctaat tcaattatag ctatatcaaa tttcacaaag actgaaatca tagatattta
     6301 tggtaagcag tatagcaata aaattacagt gatttataat gcagcacgta ttataccctc
     6361 agggcaatct ttaattaaag aatgtgattt taaatctgaa atatatggta tctgtgttgg
     6421 taatattaaa ccacacaaaa acattacacc attaatatcg tattggaaaa aaaataaaat
     6481 aaaagtaaaa ctgttatttg tgggggaaag ttcaggattt tatacatctg atataagctc
     6541 aatgttatta actaacgaat atgtttcatt tacaggtttc attactgatg aagagctgca
     6601 tgagtactat aagggagcta gtttttttat ttacccatca ctttatgaag gttttggatt
     6661 accacttcta gaagctatga gttacaaatt aaaaatattt gcatctgata tacctgtttt
     6721 tcatgagatt gctaatgatt caattgagta tttttcacca gaaaattttt ctggattaaa
     6781 agaaaaaata gaaaaattca ttgcatcgtc tcgcgaagag aaaatatcat ataactatga
     6841 atctatttta aataaatatt catggagaga ctcagttaaa ttatttgtcc atgatttatt
     6901 aatctgatta tttccgaata attgattttt ataagtgaaa aatatatgaa agagaaaaat
     6961 aaaatttatc cggtaatagt ggccggagga acaggtagca gactttggcc tctatcaaga
     7021 gagttatatc ctaaacagtt tttatgtttg caaggaaaac ttacaatgtt gcaaactaca
     7081 ctctgtagat tgaatgatct tccttgtgag gagcctattg taatatgcaa tgagcaacat
     7141 cgttttatag tagctgaaca gttacaacaa attaataaac ttacaaaaaa tataattctt
     7201 gaacctgaag gacgtaatac tgcaccagca ataacattgg ctgcattagc tgcactaatg
     7261 aataatcttg gtgaggatcc gatggtactt gttcttgcag ccgaccatat tatcgaagat
     7321 gaaaaaaagt tccaagaaac agtacgagaa gctttatttt ttgccaagaa agataagtta
     7381 gttacatttg gtattgttcc ggatcatcca gagacaggtt atggatatat caaacgagga
     7441 aatgctatag ataatgaaaa tagtttcagg gcatacagcg tttcagaatt tattgaaaag
     7501 cctaatttag taacagctaa aaaatatgta tccatggaca gttattactg gaacagcgga
     7561 atgtttctat ttcgcgcaaa tcgttacatt gaagagttag agaaatttcg tccagacatc
     7621 ttatctgcct gtcgacaagc catgtgtcat ataaataatg atcttgattt tattagaata
     7681 gatgacgagg catttcttgc ttgcccggaa gaatctatcg attatgctgt aatggaacat
     7741 accgcagatg caatcgtagt acctcttgat gctggctgga atgacgtggg ctcatggagg
     7801 gcgttgtggg agattagcca aagaaatgat gaaggtaatt cagtatatgg cgatgttatt
     7861 agctacatga ctaataatag ctatttatac gcagaatctg ggttagtgac aactgttggg
     7921 gttaaagatc taattgttgt gcagacaaaa gatgcagttc tagtagctga tcggcatgca
     7981 gtacaggatg taaaaaaggt tgtagaacag ttaaaactaa aaggacggca agaacatcat
     8041 atgcatcgtg aggtttatag gccttggggt aaatatgact caatagactc aggaaaacga
     8101 tatcaagtaa agaggatcac cgtaaaacca ggagaaggac tatcgttgca aatgcatcat
     8161 cactgttcag aacattggat agtcgttgca ggtactgcga agataacact aaataacaag
     8221 agttatttag tgagtgaaaa tgaatctatt tatatccccc ttggggcaaa gcatagttta
     8281 gaaaatcccg ggaaaattcc cttagaatta attgaggttc gtacaggttc ctatcttaag
     8341 gaagatgatg ttattcgctt aaaagaccgt tatggtagag tttaataaga gataaaaaat
     8401 cgagaattaa aatgaaaaca ttaacttgct ttaaagccta tgatatccgt ggaaaattag
     8461 gtgaagaatt aaacgaagat attgcttggc gcattggtcg tgcatatggc gaatttctta
     8521 aaccgaaaac gattgtttta ggcggcgatg tacgtctcac cagcgaaaca ttaaaactgg
     8581 cgttggctga aggtttgcag gatgcggggg ttgatgttct tgatatcggt atgtctggta
     8641 ccgaagagat ttactttgcc actttccatc ttgacgttga tggtgggatt gaaattactg
     8701 ccagccataa tcctattgat tataacggta tgaagctggt gcgtgaaggt gctcgcccca
     8761 tcagtggcga tactggacta cgtgatattc aacgactagt ggaagctaac aacttttcac
     8821 cgattaacga aagcagacgt ggcagttata agccaatcaa tctacgtaat gcttatgtta
     8881 atcacctact tagctatatc aacgttaaaa atcttactcc tctaaagctg gtgattaact
     8941 ctggtaatgg ggccgcgggc cctgtggtgg atgctattga agcccacttt aaagcgctcg
     9001 gtgcacctgt tgagttaatc aaattgcaca atacaccgga tggcaccttc cctaatggta
     9061 ttcccaatcc tctgctgccg gagtgccgtg atgacaccag caatgcagta atcaaacatg
     9121 gcgcggatat gggaattgcc tttgatggcg attttgaccg ctgtttcctg ttcgatgaaa
     9181 aaggacagtt tatagagggt tattatattg ttggactgtt ggctgaagca ttcctcgaga
     9241 aaaatccagg tgcgaagatc atccacgatc ctcgtctcta ttggaatact gttgatgtgg
     9301 ttaccgccgc aggcggcacg ccgataatgt cgaaaacagg acatgcattt attaaagaac
     9361 gcatgcgtaa ggaagatgcc atctacggtg gcgaaatgag tgctcatcac tatttccgtg
     9421 attttgctta ctgtgacagc gggatgatcc cgtggttgct ggtggccgag ttagtgtgct
     9481 tgaaagggaa gatgttgggg gagttggtac gtgatcgcat ggctgcattt ccggcgagtg
     9541 gtgagatcaa tactaaattg gcgcaaccgg cagaagcgat taaccgcgtg gagcagcatt
     9601 ttagcagcga ggcactggca gtggatcgca ctgatggtat tagcatgact tttgctgatt
     9661 ggcgctttaa tttgcgcacc tctaatactg agccggtggt gcgcctgaat gtagaatcgc
     9721 gtggtgatgt tagaatgatg gaaagaaaca cgaaaatagt attttcatta cttaatgata
     9781 atactattat ttgcaataag ggataatata acatatatga aactttatta ttacaaatcc
     9841 cctactggta actttggtga tgatttaaat gcttggctgt gggaagagtt gctgccaggg
     9901 tatttcaaat atgaaaatgg tattattttt tcaggaattg gaactattat ttctgctgat
     9961 atgccaacat cgagtaaaac tgtaatcttt ggcagtggcg ttggttatgg ttatccacca
    10021 atgaatttcg gtgacaatag atgggatgtg cgctttgtaa gaggtccgct atccgcaaaa
    10081 gtcctttcgc tgcctgctaa taaatatatt acagatagtg caattctcgt ctctaaaata
    10141 gagggttttg aaccgttgcc tgagaatgaa agaagcggga ttatttttgt tccccatcat
    10201 catgcattac atacaggtca atggcatgaa gtatgcaaat cagtaggtat tgagtttatt
    10261 gatcctaccc aagattcaaa atatgtaata caaaaaataa gaaagtcgaa acttgttcta
    10321 gctgatgcga tgcatgctgc tattattgca gattcacttc gagttccgtg gatacctctg
    10381 gtaacctcta atcaaattaa tacatttaag tggattgatt ggactttatc agttaaatta
    10441 gagtactccc catcatatat tgggccaagt tctatgcgtg aatgtttgag gaataaattt
    10501 cttcatttat atggtgagtc attttatata aaaagtttga atgctgatga ttccataaat
    10561 tgcttttata aacaaaggga tattttgtca aataaatggt ggcctattta tagtaaaata
    10621 attagaagat gtgtatatac agcccccaat cttttattaa agaaaattga acaattctcg
    10681 tctcctagat gggatgaaaa atatattagt ttagctaaga aaaaaatctt agatgcaatg
    10741 aagagagcgc caatgttaag ttccgatgat gtttatcaat cgaatttaaa taaaattctt
    10801 aatgaggtag aatgcgtaag aaaaatgtat aaataaaatt taaggccaaa gtcatgagtt
    10861 caataaaaaa aatcgtgctc aattcaagtg cactctatat tagaatgatt tttgttatgc
    10921 tagtaaatct tcttgcaaca agatttctta tggcaaattt cgggattgat ggctttggcc
    10981 tatacaatgt tatttctagt atagtcgttt taggggcttt tattaccggg attttgacag
    11041 tatctagtca acgatttatt tcttctggtt tagcaaaagc aggccatgtt ggagcaaatg
    11101 attatcttaa tgcaattttt gctgttcata tcctttgctt tataagcata ataattattc
    11161 ttgaaatatt cggatatata tatataaatg gttttttgaa acaggatgtt ctaccgataa
    11221 atgatgtgta ttatatatat catattacag ttgctggttt ttcatttagt atctttattt
    11281 catttttgaa ttctatttgt attgctgaag aaaatatgtc tgcatatgcg agattcagca
    11341 tattggatgc tacacttaaa ttacttatag catattcaac tttatttgtt cacaaaaata
    11401 ccatgatcgt atatgcatta gcaatgctat ttgaagttat tattatggtc tttgtaatgg
    11461 tcatttttat tcatagaaga tatccttatt ataaaataaa caataattat gattttatga
    11521 aaattaaaga ggttttttca tttgtaatat ggagtttatg gggaggggtt gcaacagtat
    11581 tgagtaatca ggggataaat ttattgctca attataattt tggcgtcgct ataaatgctg
    11641 caagaggtgt ttcgatgcag attaattcag cctatcttca gatcgtaaat aattttcagt
    11701 tcgctatcaa tcctcaactg gttaaatctt atgcctcaaa tgatattagt agatttgaaa
    11761 gattgttctt tctcggatca aaagtatcta ttctattttc tactattata ttttttattt
    11821 tatatgttaa cataaattat gtgctaagtt tatggttaat aaactattct gaggatatgg
    11881 tttcgttctc aaaattgata attattgatg catatataac aagttttagt actgctatta
    11941 tacttgcaat acaggctagt ggtagaataa agatatatca atctattgtg ggtgttatat
    12001 tgttgttgaa tcttccttta tcctatgcgg ctctaaaata ttggcatgag ccacagttgg
    12061 tttttgttgt tagtataaca ttatcaatat tgagtcttat ttttagaatg ctatttttac
    12121 agaaaattgt gaaaatcaag tttaggagtt ttttatttgt cattatattt cctaacatct
    12181 gtgtttttgc aattgtttca ctggttgtta attataatat atcactggca ctgacttttc
    12241 aacaatttat aattaattct gttttgataa cacttttggt tatatttctt tttatcttta
    12301 tttctttaaa tagtatggaa cggaaaatgt tgttaaataa ctttttgaaa atcactaagg
    12361 gatttaaatg aagctatcat ttgtgatacc attatttaat aaggagaaaa atattatagc
    12421 cacacttaaa tcaattattt ctgcttgtga ggaaaataat attaatgata gttatgagat
    12481 aatagtcgtt gatgatggat ctactgattc tagtggaaaa gtagtacgtg aatttattca
    12541 actaaaaaat agttgtgtca gatattattt tcaaaataat tctggcccct ctatggctag
    12601 aaatagaggt gtttctgaaa gtactggtga atatattctt tttgtagatg ctgatgatct
    12661 tcttcttcct gcttatatag cttatatatt atattgtaca aaacactatc actcctaccc
    12721 tgtctactgt gcaggatatt ctaaagttaa ttcatcggta gatatcaaag aggaaaaaat
    12781 taaatttgat tgttcacaaa taacaatagt cactgatttt tttaaaaagt ggaaagaaac
    12841 gaaatttttt tatacatcgt ctatatgcgt taaaagaagt ttttggattc agaaaaatgt
    12901 ttacttccct gtcgaacact ttacggggga ggaccaatat gcgtggtttt gtttggctca
    12961 acattgtcat ttcgtatatt tgccacaaca agtcgtttta tataaacaag gtgtggtggg
    13021 gcaattatcc tcttcgcgcc cagtgactat tgaaatccat gtccaaaaat tattagaatt
    13081 agaaaaaaat ataattttaa aaagagacgt ctcaaaactt attgataaag agttttgtta
    13141 tgtaatttct aataattttg ttgcatatca gcggttttta ggagtgaaaa tactacagaa
    13201 tagattgcga gtactcctaa attttcactg tgtgctcaaa ttaatatttt cttttatagc
    13261 acccagattt tacaattatc ttagaaaccg gcgtgatata aatacatagt tactatattt
    13321 atctaatgtg tagactctcg ttagctgaat ttatttctat cgtaaaatca ctacatacat
    13381 taatcccctg acaggagtaa acaatgtcaa agcaacagat cggcgtagtc ggtatggcag
    13441 tgatggggcg caaccttgcg ctcaacatcg aaagccgtgg ttataccgtc tctattttca
    13501 accgttcccg tgaaaagacg gaagaagtga ttgccgaaaa tccaggcaag aaactggttc
    13561 cttactatac ggtgaaagag tttgttgaat ctctggaaac gcctcgtcgc atcctgttaa
    13621 tggtgaaagc aggtgcaggc acggatgctg ctattgattc tctcaagcca tacctcgata
    13681 aaggcgacat catcattgat ggtggtaaca ccttcttcca ggacaccatc cgtcgtaacc
    13741 gtgagctttc tgcagaaggc tttaacttca tcggtaccgg tgtctccggc ggtgaagaag
    13801 gtgcgctgaa aggtccttcc attatgcctg gtgggcagaa agaagcctat gaactggttg
    13861 cgccgatcct gactaaaatc gccgcagtgg ctgaagacgg cgagccatgc gttacctata
    13921 ttggtgccga tggtgcaggt cactatgtga agatggttca caacggtatt gaatacggcg
    13981 atatgcagct gattgctgaa gcctattctc tgcttaaagg tggcctgaat ctttccaacg
    14041 aagaactggc gcagacgttt accgagtgga ataacggtga actgagcagc tacctgatcg
    14101 acatcaccaa agatatcttc accaaaaaag atgaagacgg taactacctg gttgatgtga
    14161 ttctggatga agcagcaaat aaaggtacgg gcaaatggac cagccagagt gcgctggatc
    14221 tcggcgaacc gctgtcgctg attaccgagt ctgtgtttgc acgttatatc tcttctctga
    14281 aagatcagcg cgttgccgcg tctaaagttc tctctggccc gcaagcgcag ccagctggcg
    14341 acaaggctga gttcatcgaa aaagttcgcc gtgcgctgta tctgggcaaa atcgtttctt
    14401 acgctcaagg cttctctcag ctacgcgccg cgtctgaaga gtacaactgg gatctgaact
    14461 acggcgaaat cgcgaagatt ttccgtgctg gctgcatcat ccgtgcgcag ttcctgcaga
    14521 aaatcaccga tgcatatgcc gaaaatccgc agatcgctaa cctgctgctg gctccgtact
    14581 tcaagcaaat tgccgatgac taccagcagg cgctgcgcga tgtcgtcgct tatgcagtac
    14641 agaacggtat cccggttccg accttcgccg ctgcggttgc ctattatgac agctaccgtt
    14701 ctgctgttct gcctgcgaac ctgatccaag cacagcgtga ctatttcggt gcacatactt
    14761 ataagcgcat tgataaagaa ggtgtgttcc ataccgaatg gttggattaa tctgatctaa
    14821 ctaacaataa aattgaggcc cggcgtatat tgtgccgggc ttttttttgc caattatctt
    14881 atagactaaa tttcactgct taatattaac ttaataaata tcagctattc ttataaagaa
    14941 aatctgaatt gtttttcgtt gcgttgacca tcgaacaacg tagcgttaaa acttttagct
    15001 cttatcagga tgctaaaaac atcatgattc acagttaagt taattctgag agcatgaaat
    15061 gaaaatcacc atttccggta ctggctatgt aggcttgtca aacgggcttc taatcgcaca
    15121 aaatcatgag gttgtggcat tagatatttt accgtcacgc gttgctatgc tgaatgatcg
    15181 gatatctcct attgttgata aggaaattca gcagtttttg caatcagata aaataaactt
    15241 taatgccaca ttagataaaa atgaagccta ccgggatgct ggttatgtca tcatcgctac
    15301 tccaaccgac tatgatccta aaactaatta tttcaataca tccagtgtag aatcagtaat
    15361 taaagacgta gttgaaataa atccttatgc ggttatggtc atcaaatcaa cggttcccgt
    15421 tggttttacc gcagcgatgc ataagaaata tcgtactgaa aatattattt tctctccgga
    15481 atttctccgc gaaggtaaag ccctttacga taatctccat ccgtcacgta ttgtcatcgg
    15541 tgagcgttca gaacgtgcag aacgttttgc tgcgttgtta caggaaggcg cgattaagca
    15601 aaatatcccg accctgttta ccgactccac tgaagcagaa gcgattaaac ttttcgctaa
    15661 tacctatctg gcgatgcgcg tagcatactt taatgaactg gatagctatg cagaaagttt
    15721 aggtctgaat actcgccaga ttatcgaagg cgtttgtctc gatccgcgaa ttggcaacca
    15781 ttacaacaat ccgtcgtttg gctatggtgg ttattgtctg ccgaaagata ccaagcagtt
    15841 actggcgaac taccagtctg tgccgaataa cctgatttcg gcaattgtcg atgcaaaccg
    15901 cacgcgtaaa gattttattg ccgatgccat tttgtcacgc aagccgcaag tggtgggtat
    15961 ttatcgtctg attatgaaga gcggttcaga taacttccgc gcgtcttcca ttcaggggat
    16021 tatgaagcgt atcaaggcga aaggcgttga agtgatcata tacgagccag tgatgaaaga
    16081 agactcattc ttcaactctc gcctggaacg tgatctcgcg accttcaaac aacaagccga
    16141 cgttattatc tccaaccgta tggcagaaga gcttaaggat gtggcagaca aagtctacac
    16201 ccgcgatctc tttggcagtg actaacatcc tgttatcagg gcgattttcg ccctgattct
    16261 cttatgttcc ctttgtaata attcattatt tttatcattt atcctatagc attcatggcg
    16321 attatcgcta aactatggcg acttaaaatt atttcgtccg ttagggtaat gatgagagta
    16381 gaaaataata atgtttctgg gcaaaaccat gacccggaac agattgattt gattgatttg
    16441 attgatttac tggtgcagtt gtggcgcggc aagatgacaa ttatcatctc tgtcattgtc
    16501 gctattgccc tggctatagg gtatttggcc gttgccaaag aaaagtggac ttccacagct
    16561 atcgttactc aacctgatgt ggggcaaatc gctggttata ccaacgcgat gaatgtgatc
    16621 tacggatcgg ctgtaccgaa agtctccgac attcaggctt cacttatcgg acgttacagc
    16681 actgcattct cagcattagc tgaaacgctg gataaccagg aagaagcaga aaagctgacc
    16741 attgagccta ccgttaaaaa tcagtcatta cctttagcgg tgtcttatgt tggtgaaaca
    16801 cctgaaggtg cgcagaaaca gctggcgcag tatatccagc aagttgacga ccaggtaaat
    16861 gaagaactgg aaaaagacct gaaagataac atcgcgctgc gtatgaaaaa cttgcaggat
    16921 tctctgaaaa ctcaggaagt agttgcgcag gagcagaaag atctgcgtat ccgtcagatt
    16981 caggaagcgt tgcagtatgc gaatcaggcg caggtgacaa agccacaggt tcagcagact
    17041 gaagatgtga cgcaagatac gttgttcctt ttggggagcg aagcgctgga gtcgatgatt
    17101 aagcatgagg cgacccgtcc gttggtgttc tcaccaaact actatcagac tcgtcaaaac
    17161 ctgctggata tcgaaagctt aaaagttgat gatcttgata ttcatgctta ccgttatgtg
    17221 atgaaaccga cgttacctat tcgtcgcgat agtccgaaaa aggcaattac cttgattctg
    17281 gcggtgctgc tgggcggcat ggttggcgcg gggattgtgc tggggcgtaa cgctctgcgt
    17341 aattacaacg cgaagtaatc ttttcggttt taaagaaaat gggcagggtg gtgacacctt
    17401 gcccgttttt ttttgccgga tgcgacaaca atatcgcatc cgcttacccc gcaactcact
    17461 gatgccgttt acgcaggttc tcaatcaccg tcgttaaatc caggtcctga tcctgcaaca
    17521 gtaccagcag gtgatacatc aaatcagatg cctcgttggt tagttcaacg cggtcatgta
    17581 ccgttgctgc cagtgcggtt tccacgcctt cttcgcccac tttctgcgca atgcgcttgg
    17641 tgccgctggc atacagtttg gcggtgtagg aggtttccgg gtcggcagat ttacgttcgg
    17701 cgagcagttg ttccagttgg tacagaaaca gccactggtg agcggtgtcg ccgaagcagc
    17761 tgctggtgcc tttgtggcag gttggtccga tgggattcgc caggaccagt aacgtgtcgt
    17821 tgtcgcagtc cggcgcaata ctcactacgt tgaggaaatt gcccgacgtt tcgcctttgg
    17881 tccacagtcg ctgtttagtg cgcgagaaga aggtgacttt gccgctttcg gtggttttgt
    17941 ctaaggcttc cgggttcatg tagcccagca ttaacacttc gccagatacc gcgtgttgca
    18001 caatcaccgg catcagtccg tcggtttttt cccagtccag ttgttctgtt aacatatcct
    18061 gatctccacg ccctgtgttg ccaggtacgc ttttaattca ccaatattga taatttgttt
    18121 gtggaatacg gaagctgcca gcgcaccgtc aacgtcggca tcgcggaagg cttcgaggaa
    18181 gtgttccatg gtgcccgcgc caccggaggc aatcagcggg acgtggcaaa cttcacgcac
    18241 ttttttcagt tgatcgaggt cgtaaccgtt acgcacgccg tcctgattca tcatgttgag
    18301 gacgatttct ccggcaccgc gtttttgcac ttcctgtacc cagtcgagcg tttcccactg
    18361 agtgacgcgg gtgcggcttt catc
//
