LOCUS       AB812068               20184 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli genes for O-antigen biosynthetic locus, partial
            sequence, strain: SN3B-1.
ACCESSION   AB812068
VERSION     AB812068.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 20184)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..20184
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="SN3B-1"
                     /db_xref="taxon:562"
                     /note="serogroup:O163"
     gene            <1..906
                     /gene="wcaM"
     CDS             <1..906
                     /gene="wcaM"
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis protein"
                     /protein_id="BAQ01838.1"
                     /translation="NYAILRQGFHNQIIGANITNCKFSDLQSDAIEWNVAINDSDILI
                     SDHFIERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVE
                     NGKHFVIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVI
                     KGKYLSIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNK
                     PQHLFMRNIKVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNERGQSS
                     VDIDRINHHIVNVEKINFRLPERRE"
     gene            1069..1974
                     /gene="galF"
     CDS             1069..1974
                     /gene="galF"
                     /note="O163_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ01839.1"
                     /translation="MDEIMTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVT
                     IMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGR
                     YVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQAVDAMLMTGDSYDCGKKMGYMQA
                     FVKYGLRNLKEGAKFRKGIEKLLSE"
     gene            2619..3938
                     /gene="manC"
     CDS             2619..3938
                     /gene="manC"
                     /note="O163_02"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="BAQ01840.1"
                     /translation="MMNHEKIFPIIMAGGAGSRLWPLSRELYPKQFIRLKGELTMLQA
                     TLSRLNTLMCNDPIIICNEQHRFIVAEQVRQLNKRTENIILEPVGRNTAPAVALAALA
                     AKRSRPDCDPLMLVLAADHVIQNEDAFREAVKVAIPYAENGKLVTFGIVPDTPETGEY
                     YWNSGMFMFRAGRYLEELEKYRPDILSACEKSMAVVDLDLDFIRVDEEAFLCCPEESI
                     DYAVMEHTADAVVVPMDAGWSDVGSWSSLWEVSDKTREGNVCTGDVISLNSGNNLIFS
                     DTSLIATVGVHNLIIVQTKDAVLIADRAAVQDVKKVVEKIKTDGRHEHHIHREVYRPW
                     GKYDSIDTGERYQVKRITVNPGEGMSVQMHHHRAEHWVVVAGTAKVTINGEAKLLGEN
                     ESIYIPLGATHCLENPGKIPLDLIEVRSGSYLEEDDIIRFQDRYGRV"
     gene            4045..5445
                     /gene="manB"
     CDS             4045..5445
                     /gene="manB"
                     /note="O163_03"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="BAQ01841.1"
                     /translation="MEKLTCFKAYDVRGKLGEELNEDIAWRIGRAYGEYFKPRTIVLG
                     GDVRLSSKALKLALAKGLQDAGVDVLDIGLSGTEEIYFATFHLGVDGGIEVTASHNPV
                     DYNGMKIVREGARPISGDTGLRDVQRLAEANDFPAVNEAKRGSYKQINLQKEYIDHLL
                     GYVNVANFKPLTLVINSGNGAAGPVVDALEARFKALNVPIKFVKVNNTPDGNFPNGIP
                     NPLLPECRSDTSNAVIELGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLE
                     KHPGAKIIHDPRLSWNTVDVVTAAGGTPVMSKTGHAFIKERMRKEDAIYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVTEMLCLKGKSLGEMVRDRMTAYPASGEINSTLAHPAEAIAR
                     VEQHFAKEALEVDRTDGLSMSFDEWRFNLRSSNTEPVVRLNVESRSNIELMEIKTKEI
                     MALLDNNNSGGRAENV"
     gene            5438..6691
                     /gene="wzx"
     CDS             5438..6691
                     /gene="wzx"
                     /note="O163_04"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAQ01842.1"
                     /translation="MFSQLIQQLSSFVARILVSLISLLLSVIIVRLYTKDIVGDFFLL
                     TSYSTVLAQVFLFGMAPVLNIMSSKGVQLNKIVMEIAKKNVVSMLCMFLCGLIILAFF
                     AKVDYSSLIVLSLLSGVLLIISELMKGQGMYILSQIFNGGLNNILFLILIVVFIPNKE
                     ETDLEDIIYFYALAYMCVIVGGSIYLRIKYKVSKSKGLIDDVITYSIILPIFISTVIV
                     YMFSQIDLWFVSRLFDNDVVAQYGLAIRLTAVLSFSTLSVRAIAAARIPKLMNDIQAL
                     QKDVSLSCLFSFLVSLVILSGIALFGKLFIGLVYGNSYELTWYVLLIFSFGQMINAAT
                     GPCDYLLSHTGHGRYLMIISLVSFLFLMTLLAIITIRFNSVFLFCGAVSFTICLQNLI
                     IMYVAFKKTGVLSLPLINFKRAYVS"
     gene            6688..7923
                     /gene="wzy"
     CDS             6688..7923
                     /gene="wzy"
                     /note="O163_05"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAQ01843.1"
                     /translation="MTRKMNTAVLSFMMLYILTSLISVYQTLNQDLFPGELHRYVRTI
                     ADDEVVIITTLNIISFIICYITFLLFQKFRFRLNKNYHYELNDKRIHFIIFVVLISQL
                     IFLYYTGIGKVTVNVEQRSTSSFSAFFAILKPEPFIFFYFLYYRLKPGFTFIKNKIFI
                     FNMFLFIVFKLFQGWTSFLLILFFLEVHARVQFTKNRLRYVLFIPLIIIFFGGWVYQY
                     AYVLKNEIRGAKVESITYLQGVEHLASRLSMNPNSLGAYQNYSKVINLYQQEGLALKE
                     SKAFLRPITPGGLVDKNFRNINNNVMTSYTPDLNQFTSSDFGIVMYYSILFNASLPDF
                     VLSIIMTVLLLVIAKMFFDSISSIPGQCDILFFFVLFYTFYTVSLENVFGQNFIPYIF
                     SFVIYYFLGGIKKVHFVEN"
     CDS             7935..8948
                     /note="O163_06"
                     /gene="wcqV"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01844.1"
                     /translation="MIMIVKMWPLQKESTANQYTSLILHDVIEYKPHKWNLKNVLDMR
                     FDIFHMHWPETYLNLPKRYQQLIGTLCVVLFLVVCKLFSKKIVWTVHNFKPHENHNNI
                     KISEFFRTFLVRMVDKFIFLTEVSKDEFLKIYNIDNSRLTVIHHPLYQVNECCHDISA
                     ANHSSINNKYLFFGLIRPYKNIELLMNEFIKYDSDSVLIIMGGCSNTLATELRNMKKK
                     IDFKERIKFKFGYYNEQQLQQELNQCKGVIIPYSDIMNSGVLYRAITAGVNVLLPRIR
                     YTEEVVNSLKYQGAVFYDPPLDTNDIATFNGIPSVNHNNFDVDTYNTYIKNAHYELYQ
                     TII"
     CDS             8968..10071
                     /note="O163_07"
                     /gene="wcqW"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01845.1"
                     /translation="MKNILIVCDYFYPAFKAGGPIKSLGNIAKTFNDRNYITVLTYNQ
                     DIDGQIINKSGTEIFEKNIVVYYAQNLLNFVKLYLKLYKTADIIYLNSFFSSRTTFPA
                     LMLKKTSAKVLLAPRGELTLGALTLKPLKKKIYIKLFNIFANKNEIYFQFTSEEEKNE
                     SLISLKKGFSYTVIPNMHDPIPPYIYKHKKEGEIHISFISRISPKKNLKAVLLSLLNI
                     AQGDILLSIAGNIEDEKYWAECMLIINKLPQNVKVNYLGGIKPTQVIDLLKSSHLFFL
                     PTLNENYGHAIVESMINSNVVLISDQTPWSDVQWNGGYVAGYNDTDTFKKCITECMKF
                     DESQFNNKSRQVYDYARNALTKHEYKTSTLFDI"
     gene            10256..11287
                     /gene="fnlA"
     CDS             10256..11287
                     /gene="fnlA"
                     /note="O163_08"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase"
                     /protein_id="BAQ01846.1"
                     /translation="MFKDKVLLITGGTGSFGNAVLKRFLDTNIKEIRIFSRDEKKQDD
                     MRKKYSNNKLKFYIGDVRDYSSVLNASRGVDFIYHAAALKQVPSCEFYPMEAVKTNII
                     GTDNVLEAAIANKVSRVVCLSTDKAVYPINAMGTSKAMMEKVIVAKSRNVPDEMVICA
                     TRYGNVMASRGSVIPLFVNQILTGKPITITDPNMTRFMMTLDDAVDLVVHAFKHGQNG
                     DIFVQKSPAATIEVLTHAILEIMKSADHTVNIIGTRHGEKLYEVLCSREEMLVAEDQG
                     NYYRIPCDKRDLNYEKYFEKGNKKVETIDDYNSHNTYRLNTQEMVSLLRKLTYINKIE
                     AGEKADPDE"
     gene            11280..12155
                     /gene="qnlA"
     CDS             11280..12155
                     /gene="qnlA"
                     /note="O163_09"
                     /codon_start=1
                     /transl_table=11
                     /product="L-QuiNAc synthase"
                     /protein_id="BAQ01847.1"
                     /translation="MNKRILIVGANGMLGSSLLRYFTQYSRYDVLGTVRSNSAKAKLS
                     KQGFDNIISQVDVLEYETIENVISDWKPDFLFNCVGIIKQLDAAKNNILSLSINSLLP
                     HQLAKTCTRNETKLIHFSTDCVFSGKQGNYCEESFPDAYDLYGKSKQLGEVVYDGHLT
                     LRTSIIGHEISSQHSLIDWFLSQKKYIYGYSKAIFSGMPTVYVAEIIHDYILPNPNCC
                     GLRHLSVDPIDKFSLLKLVKKQYSHNIEIIESSDLEIDRSLDSFLLRQEVGFYPASWP
                     KLIEKMNDEYNKFFR"
     gene            12160..13284
                     /gene="qnlB"
     CDS             12160..13284
                     /gene="qnlB"
                     /note="O163_10"
                     /codon_start=1
                     /transl_table=11
                     /product="L-QuiNAc synthase"
                     /protein_id="BAQ01848.1"
                     /translation="MKVVTVVGTRPEIIRLSRVMAVLDQYTEHTIIHTGQNYDYELNE
                     VFFKELEIRKPDYFLNAAGSNPAETIGNIIIEADKIFDIISPEALLILGDTNSALVSI
                     AAKRRKIPIFHMEAGNRCFDYRVPEEINRKIVDHIADINLTYSEIAREYLLREGIPAD
                     QIIKTGSPMREVLNYYNGEINKSKALEKLNLTPNEYFLVSAHREENVDSPEKLKIFIN
                     ILNKISDKYDLPIIVSTHPRTRNRMDKLNVEISNNVYFMKPFGFLDYVSLQKNARVVL
                     SDSGTITEESSILNFPALNLREVHERPEGFEEAAVMFVGLDAVRIFQGIEILDQQQRG
                     PDNRDLYLVNDYSVDNVSLKVLRIIMSYTNFVNQKVWKKQ"
     CDS             13284..14477
                     /note="O163_11"
                     /gene="wbwH"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01849.1"
                     /translation="MRIALICDDYLPDSTRVSAKMMHELACGLLREGHEPVVFCPNGG
                     VGTELKVIYLDGICIYKYPNGQTKDISKIKRAFNETMLSFNAWHYLSSEIKRKKIDGV
                     IYYSPSIFFGAFVKKIKKYWKCKSYLILRDSFPQWLVDQRIIRRNGMLEKYFRFFEKK
                     NYTAANYIGVMSSKNKELFTLQYPHYKNVDVLYNWADLNSTQDVSPSDILERLSLADK
                     VIFFYGGNIGHAQDMANLMRLAIGMRTINYVHFLFVGQGDEVELVKKTIAENALENCT
                     YLPAISQSEYKSILKVVHVGLFSLAKNHSVHNFPGKLLGYMANKLPILGSVNEGNDLM
                     QVLIGAKAGYVHVNGYDAELLQSAIKLATEEKLRNELGENGHSLLEKTFSTQSAVENI
                     LLRLK"
     CDS             14500..14997
                     /note="O163_12"
                     /gene="wbuC"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAQ01850.1"
                     /translation="MSVTVFYKEQLNELSNLASNNPRLRAHLNLHKSYQDKIQRILIS
                     LKRGTYIPPHYHKYDHQWEHFQVIEGIVDLYIFNNSGTVLDIINLGDVNGALFAQIEP
                     YTIHTLVCRSPYASVIEIKEGPFVEAEAKIVPSWVYPEGCREYLRSDIVSMLETLKIN
                     EVYKL"
     gene            15201..16607
                     /gene="gnd"
     CDS             15201..16607
                     /gene="gnd"
                     /note="O163_13"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ01851.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLKYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            16856..18022
                     /gene="ugd"
     CDS             16856..18022
                     /gene="ugd"
                     /note="O163_14"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ01852.1"
                     /translation="MKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKKQSP
                     IVDKEIEEYLATKDLNFRATTDKYDAYKNADYVIIATPTDYDPKTNYFNTSSVEAVIR
                     DVTEINPNAVMVIKSTIPVGFTKSIKERLDIDNLIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            18112..19146
                     /gene="wzz"
     CDS             18112..19146
                     /gene="wzz"
                     /note="O163_15"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ01853.1"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLV
                     QLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGP
                     AVPKVSDIQTSLIGRYSTAFSALAETLDNQEEPEKLTIEPTVKNQSLPLAVSYVGETA
                     EGAQKQLAQYIQQVDDQVNEELEKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQ
                     IQEALQYANQAQVTKPQVQQTEDVTQDTLFLLGSEALESMIKHEATRPLVFSSNYYQT
                     RQNLLDIESLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLG
                     RNALRNYNAK"
     gene            complement(19244..19855)
                     /gene="hisI"
     CDS             complement(19244..19855)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ01854.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFHNVVNITPDCDNDTLLLLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ"
BASE COUNT     6007 a   3707 c   4372 g   6098 t
ORIGIN
        1 aattacgcca tcttacgcca gggatttcat aaccagataa tcggtgccaa catcaccaat
       61 tgtaagttca gcgacttaca gagcgatgcc attgaatgga acgtggcgat taacgacagt
      121 gatattttga tctccgacca cttcatcgag cgcatcaact gtactaatgg caaaatcaac
      181 tggggtatcg gcataggcct tgcgggaagt acctacgata ataactaccc ggaagaccag
      241 gcagtgaaaa actttgtcgt ggcgaatatc acgggatcgg attgtcggca gttgatccat
      301 gttgaaaatg gtaaacattt tgttattcgt aatatcaaag cccgcaatat cacgccggat
      361 ttcagtaaga aagcaggtat tgataacgcg acggtcgcta tttacggttg tgacaatttc
      421 gtgattgata atattgaaat gattaatagc gccgggatgt taatcggcta tggggtaatt
      481 aaaggcaaat atctctcgat accgcaaaat ttccgagtga ataatattca actggataac
      541 acccatcttg cttataaatt gcgcggtatc caaatctccg ccgggaatgc tgtctccttt
      601 gtggcgctga ctaacattga gatgaagcgt gcctcgcttg agctacacaa taaaccgcaa
      661 caccttttta tgcgtaatat caaggtgatg caggaatcct ctgttggacc agcattgagc
      721 atgaacttcg acatgcgcaa agacgttcgc ggcgtcttta tggcgaaaaa agaaacactg
      781 ctgtctcttg caaatgttca tgcggtgaat gaaagagggc aaagctccgt cgatatcgac
      841 aggataaatc accatattgt taatgtggaa aagattaact ttagattgcc ggaacggagg
      901 gagtagattt gcgaccattc ctggaaaaat ggagccatac ttaggaacaa tgctactgca
      961 atccacaacg aagcggcgta acatcacaag taattcagta atcaattcag ggtaattgat
     1021 gctggcgaaa aaaatcgaac aagctataat tcagcaacca ttttacaggt ggatgaaata
     1081 atgacgaatt taaaagcagt tattcctgta gcgggtcttg ggatgcatat gttgcctgcc
     1141 actaaggcga ttcccaaaga gatgctaccg atcgtcgaca agccaatgat tcagtacatt
     1201 gttgacgaga ttgtggctgc agggatcaaa gaaatcctcc tggtaactca cgcgtccaag
     1261 aacgcggtcg aaaaccactt cgacacctct tatgaattag aatctctcct tgaacagcgc
     1321 gtgaagcgtc aactgctggc ggaagtacag tccatttgcc cgccgggcgt gaccattatg
     1381 aacgtgcgtc agggcgaacc tttaggtttg ggtcactcca ttttatgtgc acgacccgcc
     1441 attggtgaca atccatttgt cgtggtgctg ccggacgttg tgatcgacga cgccagcgcc
     1501 gacccgctgc gctacaacct tgcagccatg attgcgcgct tcaacgaaac gggccgcagt
     1561 caggtgctgg caaaacgtat gccgggcgat ctctctgaat actccgtcat tcagacaaaa
     1621 gaaccactgg accgtgaagg taaagtcagc cgcattgttg aatttatcga aaaaccggat
     1681 cagccgcaga cgctggactc agacatcatg gccgttggtc gctatgtgct ttctgccgat
     1741 atttggccgg aacttgaacg cactcagcct ggtgcatggg ggcgtattca gctgactgat
     1801 gccatcgctg aactggcgaa aaaacaggct gttgatgcaa tgctgatgac aggcgacagc
     1861 tacgactgcg gtaaaaaaat gggctatatg caggcgtttg tgaagtatgg actgcgtaac
     1921 ctaaaagaag gggcgaagtt ccgtaaaggg attgagaagc tgttaagcga ataatgaaaa
     1981 tctgaccgga tgtaacggtt gataagaaaa ttataacggc agtgaagatt cgtggcgaaa
     2041 gtaatttgtt gcgaatattc ctgccgttgt tttatataaa caatcagaat aacaacgagt
     2101 tagcaatagg attttagtca aagttttcca ggattttcct tgtttccagg gcggattggt
     2161 aagacaatta gcgtttgaat ttttcgggtt aagcgcgagt gggtaacgct cgctacatcg
     2221 taggcatgca tgcagtgctc tggtagctgt aaagccaggg gcggtagcgt gtctgatgaa
     2281 taaatcgatt tgttcaatat agtaatctac tagaaaaact tttcatccct cataattatc
     2341 gatgtcaata tttgaaatat aattagcaac caacagttga ttaaaatagt tcaatgtttc
     2401 tgcataataa ttatattgat ggtaaaaaat taaacataac gaaccctatt gttttatgcg
     2461 tttatttata acgtaaggcc catttaatag ctctgtaaat aatgtaattc acttaaattt
     2521 tctttgtttt accaaatacc ctttggttta accgaatttt atatttaacc ttatcttcaa
     2581 ggtatgagtt atagctctgg gccttagaat gagttaatat gatgaatcac gaaaaaattt
     2641 tcccaataat catggctggt ggggcaggta gtcgtctgtg gccactgtcc cgcgagcttt
     2701 atccaaaaca attcattcgc cttaaaggcg aactcaccat gttacaggca actctaagcc
     2761 gtttgaatac tttgatgtgt aatgatccga ttattatatg caacgaacag caccgcttta
     2821 ttgttgcaga gcaggtgcgc cagctgaaca aacggaccga aaatatcatt ttggagcctg
     2881 tcggtcgtaa caccgctccg gcagttgccc tcgcggcgct ggcggcaaaa cgcagtcgcc
     2941 cggactgtga tccgttgatg ctggttctgg ctgctgacca tgttattcag aacgaagatg
     3001 catttcgcga agcggtaaag gtggctatcc cttacgcgga aaacggcaag ttggtgactt
     3061 tcggcatcgt gcctgatacg ccggaaacgg gtgagtatta ctggaacagt ggtatgttca
     3121 tgttccgtgc aggtcgctac ctggaagaac ttgaaaaata ccgtccggat atcttaagtg
     3181 cctgcgaaaa atcgatggca gtggttgatc ttgatctcga ttttatccgc gtggatgaag
     3241 aagcctttct ctgctgtccg gaagagtcca ttgactatgc agtgatggaa catacggcgg
     3301 atgccgtggt ggtgccaatg gatgcgggct ggagtgatgt cggttcatgg tcttctttat
     3361 gggaagttag cgataaaact cgtgagggaa atgtttgcac tggagatgtg atttcattga
     3421 actctggcaa taatcttatt ttctccgata caagcttaat tgccacagtt ggtgtgcata
     3481 atctaattat agtacagact aaagacgcgg tactgattgc tgaccgtgcc gctgtgcaag
     3541 acgttaaaaa agtggtggag aagatcaaga ctgatggtcg ccatgaacac catattcatc
     3601 gtgaagtcta ccgtccatgg ggtaaatatg actccatcga caccggtgag cgttaccagg
     3661 tgaaacgcat cacagtgaat ccgggtgaag gaatgtcggt gcagatgcac catcaccgtg
     3721 ccgaacactg ggtcgtggtg gctggtaccg ccaaagtgac catcaatggt gaagcgaagc
     3781 tgctcggtga aaacgagtcc atttatattc cgctgggtgc gacgcattgc ctggaaaacc
     3841 cggggaaaat tccgctcgac ttaattgagg tgcgctctgg ctcctatctg gaagaggacg
     3901 acatcatccg cttccaggat cgctacgggc gggtgtagca ctccgcatca tgcccagtgg
     3961 cgctgagctt gctggatcta cgaatgaaaa aatagatttg accattcaag ggtcaggact
     4021 aattttgcct aaaaaggagc catcatggaa aaattaacct gttttaaagc ttacgatgtt
     4081 cgcggcaagc taggtgagga gctgaatgaa gacattgcgt ggcgcatcgg ccgcgcgtat
     4141 ggcgaatatt ttaagccacg aactatcgtc ttaggcggcg atgtgcgtct gtccagcaaa
     4201 gccctgaagc tggcgttggc gaaaggactg caggacgctg gtgttgatgt gcttgatatc
     4261 ggcctttccg gtaccgaaga gatctatttt gcaactttcc atttgggcgt ggacggtggt
     4321 attgaagtga cagctagcca taacccggtg gactataacg gtatgaagat tgtgcgcgaa
     4381 ggtgcacgtc ctatcagcgg tgataccggc ctgcgcgatg tgcagcgctt ggctgaggcc
     4441 aacgacttcc cggcggtgaa tgaagccaaa cgcggtagtt ataagcaaat caacttgcaa
     4501 aaagagtaca tcgaccactt gctaggctat gtcaacgtgg caaacttcaa accactcact
     4561 cttgtaatca attccggaaa tggagcggca ggaccggttg tcgatgcact tgaagctcgc
     4621 tttaaggcgc tgaacgtgcc tataaaattc gttaaagtga acaatacgcc tgacggcaac
     4681 ttcccgaacg gtattcctaa cccgttgttg ccagagtgcc gttctgatac aagcaatgcg
     4741 gtgattgagc tcggtgcaga catgggaatt gcctttgacg gtgatttcga ccgctgcttc
     4801 ctgttcgacg aaaaaggaca gtttatcgag ggttactata tagttggtct gctggcggaa
     4861 gcctttcttg aaaaacaccc tggtgcaaaa attatccatg atccgcgtct ctcctggaac
     4921 actgttgatg tggtgactgc cgcaggtggc acgccggtaa tgtcgaaaac aggacacgcc
     4981 tttattaaag aacgtatgcg caaggaagac gccatctacg gtggcgaaat gagcgcgcac
     5041 cattacttcc gtgatttcgc ttactgtgat agcggcatga tcccatggtt gctggtgacg
     5101 gagatgctgt gtctgaaggg caagtctctg ggcgagatgg ttcgcgaccg catgactgcc
     5161 tatcctgcaa gcggtgaaat caacagcacc ttggcacacc ccgctgaggc gatagcgcgg
     5221 gtggagcagc actttgcgaa agaggcactg gaggtggatc gcaccgatgg tcttagcatg
     5281 tcgtttgatg aatggcgctt caatctgcgt tcgtcgaata ccgagccggt ggtacgtttg
     5341 aacgtcgaat cccggtctaa tatcgagcta atggaaataa aaactaaaga gataatggct
     5401 ctattagata ataataattc agggggccga gctgagaatg tttagtcagc taattcagca
     5461 gttgagctcg tttgtagcga ggatattagt atcattaatt tctcttcttc tcagcgtgat
     5521 aattgtacgg ttatatacga aagatatagt tggtgatttt tttttgctaa ccagttattc
     5581 gactgttttg gcccaagtgt tcttgtttgg aatggcacct gttttaaaca ttatgtcatc
     5641 caagggggtt cagttaaata aaatagtaat ggagatagcc aagaaaaatg tagtatctat
     5701 gctatgtatg tttttatgtg gcttaattat actggctttt tttgctaaag ttgattattc
     5761 gagtttaatt gtgctttcac ttctttcagg agttctatta attattagtg aactaatgaa
     5821 gggacaaggt atgtatattc tctcccaaat cttcaatgga ggtttgaata acattctctt
     5881 tcttattctt atagtcgttt ttataccaaa taaagaagaa acagatctcg aggatattat
     5941 ttatttttat gcgttagcat atatgtgtgt tattgtaggt ggttctatat acttgcgcat
     6001 taaatataag gtaagtaaga gtaaaggatt aattgatgat gttattacgt attcaattat
     6061 tttaccgata ttcatatcaa ctgttattgt atatatgttc tcacaaatag acctgtggtt
     6121 tgtatctcgt ttatttgata atgatgtagt tgctcagtat ggattagcaa ttagattgac
     6181 ggcagtattg agtttttcga ctttatcagt tagagctata gcagcagcaa gaatcccaaa
     6241 attaatgaac gacattcagg cgttgcaaaa agatgtatcc ctcagttgtt tattttcatt
     6301 tttagtgagt ttagtgattt taagtgggat agcattattt ggcaaattat ttattggcct
     6361 tgtttatggc aacagctatg aattaacttg gtatgttcta ctaattttct catttggaca
     6421 gatgattaat gctgcaactg gtccctgcga ttatttacta agtcatacag ggcatggaag
     6481 ataccttatg ataatctcac ttgtttcatt cttattttta atgactctat tggcaataat
     6541 aacaataaga ttcaacagtg tgtttttatt ctgtggcgct gtatcattta caatctgctt
     6601 gcaaaatctg attataatgt acgtagcatt taaaaaaacg ggtgtacttt cactaccctt
     6661 aataaatttt aaaagagcat atgtatcatg acaaggaaaa tgaatactgc agttttatca
     6721 ttcatgatgt tatatattct tactagtctt atttcagttt atcaaacatt gaatcaagat
     6781 ttatttcctg gtgaacttca tagatatgta agaactattg ctgatgatga ggttgtgatt
     6841 ataacaactc tgaatattat atccttcata atatgttata taacattttt gttatttcaa
     6901 aaatttaggt tcaggctgaa caaaaactat cattatgaat tgaatgataa gcgtatccat
     6961 ttcataattt tcgtagtgtt aatatctcaa cttatttttc tctactacac aggtattggt
     7021 aaagttactg ttaatgtcga acagcgtagt acttcatcat ttagcgcttt ttttgcaatc
     7081 ttgaagccag aaccttttat ttttttctat tttttatatt atagattgaa acccggattt
     7141 acttttatta aaaataagat ttttattttt aatatgtttt tgtttattgt ttttaaatta
     7201 tttcaagggt ggacaagttt tttgttaata cttttctttc ttgaagttca tgccagagta
     7261 caatttacta aaaacaggtt gagatatgta ctctttatac ctttaattat tatttttttt
     7321 ggtggctggg tttatcagta tgcttatgta ttaaagaatg aaattagggg ggcgaaagtt
     7381 gaaagtatta cgtacttgca gggagtggaa catcttgcat cacgtttatc gatgaatcct
     7441 aactcgcttg gggcttatca aaattattct aaagttataa acttatatca gcaagaaggt
     7501 cttgctctca aagaatcaaa agcatttctt cgacctatta caccaggtgg tttggtggat
     7561 aaaaatttca gaaatataaa taataatgta atgacatcat atacaccgga tctaaatcaa
     7621 tttacgagtt cagattttgg cattgtaatg tactattcaa tattgtttaa tgcaagtcta
     7681 cctgattttg tattaagtat aataatgact gttttactgt tagtaattgc taaaatgttt
     7741 tttgattcaa ttagtagtat tcctggacag tgcgatattt tattcttttt tgtattgttc
     7801 tatacctttt atactgttag tttagaaaat gtttttgggc aaaactttat tccttatatc
     7861 tttagttttg taatatatta ttttttaggt ggaataaaga aagtacactt tgtagaaaat
     7921 taatttgaga ttgtgtgatt atgatagtta aaatgtggcc tcttcaaaaa gaatcaacgg
     7981 caaatcaata tacttcgttg attctacatg atgtgattga atataaacct cacaaatgga
     8041 atctgaaaaa tgtgttggat atgaggttcg atattttcca tatgcattgg cctgaaactt
     8101 atttaaactt acctaaacgg tatcaacagt taattgggac tctgtgtgtt gtattgtttt
     8161 tagttgtatg caagcttttt tctaaaaaaa tcgtatggac cgttcataat ttcaagcctc
     8221 atgaaaatca caataatatt aagatatcag aattttttcg tacattcctt gttcgaatgg
     8281 tagataaatt tattttttta acagaagtta gcaaagatga atttctgaaa atttacaata
     8341 ttgataattc aagattaact gtgatacatc acccactgta tcaagtaaat gagtgttgcc
     8401 atgatatttc agcagctaat cattcatcaa ttaataataa atatcttttt ttcggattaa
     8461 ttaggcctta taaaaacata gagttattaa tgaatgaatt tattaaatat gattctgatt
     8521 cggtattgat aattatggga gggtgctcca acacattagc tactgaatta aggaacatga
     8581 agaaaaaaat tgattttaaa gaacgcatca aatttaaatt tgggtactat aatgaacaac
     8641 aacttcagca agagctcaat caatgtaaag gtgtaataat accatactca gacataatga
     8701 attctggtgt gctatatcgt gcaataactg cgggtgtaaa tgtgttactg cctcgtataa
     8761 gatatacaga agaagtggtc aattctctta aatatcaagg tgctgtattt tatgaccctc
     8821 cacttgatac gaatgatata gcgacgttta atggcatacc ctcagtaaat cataataatt
     8881 ttgatgtgga tacatataac acatatataa aaaatgcaca ttatgaactt tatcaaacca
     8941 taatttaaga cttaaattaa gcgtaaaatg aagaatatat taatagtttg tgattatttt
     9001 tatcccgctt tcaaagcggg agggcctatt aaaagtctcg gaaatatagc caaaactttc
     9061 aatgacagaa attacataac cgtattgacc tacaatcagg atattgatgg tcagatcata
     9121 aataaatctg gcactgaaat ttttgaaaaa aatattgtcg tttattatgc tcaaaacctg
     9181 ctgaattttg ttaaattgta tttaaaactt tacaaaacag ctgatataat ctatttaaat
     9241 agtttttttt cgagtagaac tacgtttcct gcattaatgc ttaagaagac tagcgcgaag
     9301 gttttgctgg cccctcgtgg tgaactaaca ttaggtgcat tgacgttaaa accattaaaa
     9361 aagaaaatat atataaaatt atttaatatt ttcgctaaca aaaatgaaat ttattttcaa
     9421 tttacatctg aagaagaaaa gaatgaatca ttgatatcct taaaaaaagg attttcatat
     9481 actgtcattc ctaatatgca tgatccgatt ccaccttata tatataagca taagaaggaa
     9541 ggtgaaatcc atatttcatt tatttcgcgt atttccccca aaaaaaatct caaagcagtg
     9601 ctattgtctc ttttaaatat agcccaaggc gacatactcc ttagtattgc aggaaatatc
     9661 gaggatgaaa aatattgggc ggaatgtatg ttgataataa ataaattacc acagaatgtt
     9721 aaagtaaatt atctcggtgg aatcaagcct actcaggtaa ttgatttact taagagctcg
     9781 catttgtttt tcttgccaac attaaatgag aactatgggc atgctattgt tgagtccatg
     9841 ataaactcaa atgttgtgct aatatccgat caaacaccat ggtccgatgt gcaatggaat
     9901 ggcggttatg ttgcaggtta taatgatact gatacattca agaagtgtat aaccgaatgt
     9961 atgaagttcg atgagtcgca atttaataat aaatcacgac aagtctatga ctatgcacga
    10021 aatgctttaa ctaaacatga atataaaaca tcaactttat tcgatattta gatgtaaatt
    10081 tatgcttttt cattttactt aagtttctat gtaaacagtt attcccaatt aacggtgtag
    10141 tattatttaa catcttttat ttaaaatttt caatgtggta atgaattgag ttttattgct
    10201 cgcttttctt catataaaaa cactttacgt gtttgctcac tctagaggaa ttagtatgtt
    10261 taaagataag gttttactta ttacaggtgg cacaggttca tttggtaatg ctgtattaaa
    10321 gcgtttttta gatacgaata tcaaagaaat tcgcattttt tcgagagatg agaaaaaaca
    10381 agatgatatg cgaaagaaat atagtaacaa taaactcaag ttttatatcg gtgacgtaag
    10441 ggattattcg agtgtgttaa atgcatctcg aggagttgat tttatttatc atgcggctgc
    10501 attaaaacag gttccttctt gtgaatttta tccaatggaa gcagtaaaaa ctaatattat
    10561 tggcactgat aatgttctgg aagcagctat tgccaataaa gtgtcaagag tagtgtgttt
    10621 gagtactgat aaagcagtat acccaatcaa tgctatggga acatctaaag caatgatgga
    10681 aaaggtcata gttgctaaat ctcgtaatgt tcctgatgaa atggttatat gtgcaacacg
    10741 ttatgggaat gttatggctt caagaggttc tgttattccc ctttttgtta atcagatatt
    10801 aactggtaaa ccgattacaa tcaccgatcc aaatatgact cgtttcatga tgacattaga
    10861 tgatgcagtt gatttggttg tacatgcttt taaacacgga caaaatggag atatttttgt
    10921 acagaaatct cctgctgcta ccattgaagt tttgactcat gcgattctag aaattatgaa
    10981 atcggctgat cacactgtta atattatcgg tacacgtcat ggcgaaaaac tatatgaggt
    11041 tttatgtagc agagaagaga tgttggtagc cgaagatcaa ggtaactatt atagaatacc
    11101 gtgcgataag cgagatttga attatgaaaa atattttgag aaaggcaaca aaaaagttga
    11161 aacaatagat gattataatt cacataatac atatcgttta aatactcaag agatggtttc
    11221 attactacgt aaacttacct atatcaataa aattgaagct ggtgaaaagg ctgatcctga
    11281 tgaataaaag aatattgatt gttggtgcta atggcatgct gggcagcagt ctgctacgat
    11341 attttaccca atatagtaga tatgatgttt tgggtactgt acgtagtaac agtgcaaagg
    11401 caaaactatc taaacaaggt tttgataata tcatatctca agttgatgtg cttgaatatg
    11461 aaacaatcga gaatgttatt tcagactgga aaccagattt tttatttaat tgtgtaggta
    11521 ttatcaaaca gcttgacgct gcgaagaata acatactttc attatcaatc aattctttgt
    11581 tgccacacca acttgctaaa acatgtactc gtaatgaaac taaactaata catttttcta
    11641 ctgattgcgt atttagtggt aagcaaggta attattgtga agaaagcttt ccagatgctt
    11701 acgatctata tggaaaatca aagcaacttg gtgaagtggt ttatgacggt catttaactt
    11761 tacggacttc aattattggg catgaaatct caagccagca cagtttgatc gattggtttt
    11821 tatctcaaaa aaaatatatt tatggatact caaaagctat tttttctgga atgccaacag
    11881 tatatgtagc cgagattatt cacgactata ttcttccaaa tccaaactgt tgtgggctaa
    11941 gacaccttag tgttgatcct attgataaat tcagcttatt gaagctagta aaaaagcaat
    12001 actctcacaa tattgagatt atagaatcaa gtgatttaga gattgatcgt agtcttgatt
    12061 catttctatt acgccaagaa gtggggtttt atccagcaag ttggcctaaa ctgattgaga
    12121 aaatgaatga tgaatacaat aaattcttcc gttaaaaaaa tgaaagttgt tactgttgtg
    12181 ggtaccagac cggagataat tcgtttatcg agagtaatgg ctgttcttga tcagtacaca
    12241 gaacatacca tcattcacac tggacagaac tatgattatg aacttaatga ggttttcttc
    12301 aaggagttag agatcagaaa accagattac ttccttaatg cagcaggttc taacccagct
    12361 gaaactattg gtaatataat tattgaagca gacaaaattt ttgacataat ttctccagag
    12421 gctcttttaa tacttgggga tacaaatagt gcactagttt ctattgcagc taaaagacgt
    12481 aaaattccaa tatttcatat ggaagcagga aacagatgtt ttgattatcg agttcctgag
    12541 gaaattaatc gaaagattgt ggatcatatt gccgatataa accttactta cagcgaaatt
    12601 gctcgtgagt acttgttgcg tgaagggatt cctgcagatc agattatcaa aacaggtagc
    12661 ccaatgcgtg aggttttaaa ttattataat ggagagataa ataaatctaa agcactcgaa
    12721 aagttgaatt taactcctaa tgagtatttt ctggtcagcg cacatcgaga agagaatgta
    12781 gattctcctg aaaaattaaa aatttttatt aacattctta ataaaatatc ggataaatat
    12841 gatttgccaa taatagtatc tacgcaccca cgaacccgta atcgaatgga taagcttaat
    12901 gtagaaataa gcaataatgt ttattttatg aaaccattcg gtttcttaga ttatgtttct
    12961 ttgcaaaaga atgctcgcgt agttctgtct gacagcggta caataacgga agaatcttcg
    13021 attttaaatt ttcccgctct taatttacgt gaagttcatg aacgtccgga aggtttcgaa
    13081 gaagctgccg taatgttcgt tgggctggat gctgttcgta tttttcaagg tattgaaatt
    13141 ttggatcaac agcagagagg accggataat cgagatttgt atttggtcaa tgattattcg
    13201 gttgacaatg tatcgctaaa agtccttaga atcataatga gctatactaa ttttgttaac
    13261 caaaaggttt ggaaaaagca ataatgcgaa tagcgttaat ctgtgatgat tatctgcctg
    13321 atagcacacg tgttagtgca aaaatgatgc atgaattggc ttgtggactt ttaagagaag
    13381 gccatgagcc ggttgtattt tgccctaatg gtggtgttgg tactgaatta aaagtaattt
    13441 atttggatgg aatatgtatt tataaatatc caaatggaca aacaaaagat atatcaaaaa
    13501 ttaagcgtgc atttaacgaa actatgcttt cattcaatgc atggcattac ctttcaagcg
    13561 aaattaaacg taaaaaaatt gatggtgtta tttattattc accatcaatt ttctttgggg
    13621 cttttgtaaa aaaaattaaa aaatattgga aatgtaaatc atatctaatt ttacgtgatt
    13681 catttcccca atggttagtt gaccaaagga taattcgtag aaatggtatg cttgagaaat
    13741 attttcgttt ttttgaaaag aagaattata ctgcagccaa ttatattggt gtaatgtcat
    13801 ctaaaaataa agaacttttt acattacagt atccccatta caaaaacgta gatgtcttat
    13861 ataattgggc agatcttaat agcactcaag atgtttcacc aagtgatatt ttagaaaggc
    13921 tatcattggc tgataaagtt atatttttct atggaggaaa tataggtcat gctcaagaca
    13981 tggcaaattt aatgagattg gcaataggta tgcgtactat taattacgtt cattttcttt
    14041 ttgttggaca aggggatgag gtcgaacttg ttaaaaaaac aattgccgaa aatgcacttg
    14101 agaactgtac atacttacct gcaattagtc agtcggaata taaatcaatt ttaaaggttg
    14161 ttcatgtagg gttgtttagc cttgcaaaga atcattctgt gcataatttt ccgggcaaac
    14221 ttctaggata tatggcaaat aaattaccaa ttttaggtag tgtgaatgaa ggtaatgatc
    14281 ttatgcaagt gctcattggc gcaaaggctg gatatgtgca cgttaatgga tatgatgcag
    14341 aattattgca atcagctata aaattagcta cggaagagaa attaaggaat gaattaggag
    14401 aaaatggtca ttcactttta gagaagacct tttctacgca atctgctgtc gagaacattt
    14461 tgttacggct taagtgaatt attaaatgta ggaattgata tgtcggttac tgtattttat
    14521 aaagagcagt taaatgaatt gtcaaatctt gcaagtaata accctcggct aagggctcat
    14581 ttaaacttac ataagagtta tcaagataag attcagagga ttttaatttc cttaaagagg
    14641 ggaacataca taccgccaca ttatcataaa tatgatcatc agtgggaaca ttttcaagtg
    14701 atcgagggta tagtcgattt atatatattt aataattcag gtactgtctt agatattatt
    14761 aatttgggag atgtaaacgg tgctttattt gcacaaatag aaccctatac catacataca
    14821 cttgtctgcc gttctcctta tgcttctgta atcgaaatta aagaagggcc ttttgttgag
    14881 gcagaggcta aaattgttcc ctcttgggtg tatccggaag gctgtagaga gtacttacgt
    14941 tctgatatcg tatcaatgct tgaaactctc aagattaatg aagtatataa gctttaactg
    15001 attaaggata atatggaatc aatttaatta aatcaatcac cacctcccta ggatgtggtt
    15061 taggaataac aattataaaa tttcttaatg ttgaaagagg ctgcagtttc cctctatttt
    15121 tttattagga cctgagttag catcaaagtt acattcaagc cgcatacatc gcggtgaaca
    15181 ccccctgaca ggagtaaaca atgtcaaagc aacagatcgg cgtcgtcggt atggcagtga
    15241 tggggcgcaa ccttgcgctc aacatcgaaa gccgtggtta taccgtctct attttcaacc
    15301 gttcccgtga aaagacggaa gaagtgattg ccgaaaatcc aggcaagaaa ctggttcctt
    15361 actatacggt gaaagagttt gttgaatctc tggaaacgcc tcgtcgcatc ctgttaatgg
    15421 tgaaagcagg tgcaggcacg gatgctgcta ttgattctct caagccatac ctcgataaag
    15481 gtgacatcat cattgatggc ggtaacacct tcttccagga taccatccgt cgtaaccgtg
    15541 agctttctgc cgaaggcttt aacttcattg gtaccggtgt ttccggtggt gaagaaggtg
    15601 cgctgaaagg tccttccatt atgcctggtg ggcagaaaga agcctatgaa ctggttgcac
    15661 cgatcctgac caaaatcgcc gcagtggctg aagatggcga accgtgtgtt acctatattg
    15721 gtgccgatgg cgcgggtcac tatgtaaaaa tggttcacaa cggtattgaa tacggtgata
    15781 tgcagctgat tgctgaagcc tactctttgc ttaaaggtgg cttgaacctt tccaacgaag
    15841 aactggcgca gacctttact gagtggaata acggtgaact gagcagctac ctgattgaca
    15901 tcacaaaaga catcttcact aaaaaagatg aagacggtaa ctacctggtt gatgtgattc
    15961 tggatgaagc ggctaacaaa ggtaccggta aatggaccag ccagagcgcg ctggatctcg
    16021 gtgaaccgct gtcgctgatt accgagtctg tgtttgcacg ttatatctct tctctgaaag
    16081 atcagcgtgt tgccgcatct aaagttctct ctggcccgca agcgcagcca gctggcgaca
    16141 aggctgagtt catcgaaaaa gttcgtcgtg cgctgtatct gggcaaaatc gtttcttacg
    16201 ctcagggctt ctctcagcta cgcgccgcgt ctgaagagta caactgggat ctgaaatacg
    16261 gcgaaatcgc gaagattttc cgtgctggct gcatcatccg tgcgcagttc ctgcagaaaa
    16321 tcaccgatgc ttatgccgaa aatccgcaga tcgctaacct gctgctggct ccgtacttca
    16381 agcaaattgc cgatgactat cagcaggcgc tgcgtgatgt cgttgcttat gcagtacaga
    16441 acggtatccc ggttccgacc ttcgccgctg cggttgccta ttatgacagc taccgtgccg
    16501 ctgttctgcc tgcgaacctg atccaggcac agcgtgacta tttcggtgcg catacttata
    16561 agcgcattga taaagaaggt gtgttccata ctgaatggct ggattaatct gatttaaatc
    16621 aattaaccaa cacaaggccc ggagaaaccc tccgggcttt tttattatac aaagcggcag
    16681 gttatggcct ttttttataa tttatgatta aaaaagcgat ataatacaga gccgcacagc
    16741 aggatcgctg tcttgacagt tcaaccgcat cagcgttaaa aatcccgcag tagatgaagt
    16801 tgtggtggtg gactaatgac cactctaaat gtttaaccgg aagaagtcag agctaatgaa
    16861 aataacaatt tcaggaacag gttatgttgg tctttcaaat ggtattctga ttgcgcaaaa
    16921 tcacgaagtg gttgcactgg atatcgttca ggccaaagtg gacatgctta acaagaagca
    16981 gtcaccgatt gttgataagg agattgaaga gtatctggcg actaaagatc tcaatttccg
    17041 cgctacgaca gataagtatg acgcgtataa aaatgccgat tacgttatta ttgccacgcc
    17101 taccgattat gacccgaaaa caaattattt taatacctca agcgtggaag cggtcatccg
    17161 tgatgtgaca gaaattaatc ccaacgcggt aatggtgatt aaatctacaa ttccggtagg
    17221 tttcaccaaa tcaattaaag aacgtctgga tatcgataac cttattttct ctccggaatt
    17281 tctccgtgaa ggtaaagctc tttacgataa tctccatccg tcacgtattg tcatcggtga
    17341 gcgttcagaa cgcgcagaac gttttgctgc gttgttacag gaaggcgcga ttaagcaaaa
    17401 tatcccaacc ctgtttaccg actccactga agcagaagcg attaaacttt tcgctaatac
    17461 ctatctggcg atgcgcgtag catactttaa tgaactggat agctatgcag aaagtttagg
    17521 tctgaatact cgccagatta tcgaaggcgt ttgtctcgat ccgcgtattg gcaaccatta
    17581 caacaacccg tcgtttggct atggtggtta ttgtctgcca aaagatacca agcagttact
    17641 ggcgaactac cagtctgtgc cgaataacct gatttcggca attgtcgatg caaaccgcac
    17701 gcgtaaagat tttattgccg atgccatttt gtcacgcaag ccgcaagtgg tgggtattta
    17761 tcgtctgatt atgaagagcg gatcagataa cttccgtgcg tcttccattc aggggattat
    17821 gaaacgtatc aaggcgaaag gcgttgaagt gatcatctac gaaccggtga tgaaagaaga
    17881 ttcattcttc aactctcggc tggaacgtga tctcgccact ttcaaacaac aagccgatgt
    17941 cattatttcc aaccgtatgg cagaagagct taaggatgtg gcagacaaag tctacacccg
    18001 cgatctcttt ggcagtgact aacatcctgt tatcagggcg attttcgccc tgattctctt
    18061 atgttccctt tgtaataatt cattattttt atcatttatc ctatagcatt catggcgatt
    18121 atcgctaaac tatggcgact taaaattatt tcgtccgtta gggtaatgat gagagtagaa
    18181 aataataatg tttctgggca aaaccatgac ccggaacaga ttgatttgat tgatttactg
    18241 gtgcagttgt ggcgcggcaa gatgacaatt atcatctctg tcattgtggc tattgccctg
    18301 gctatagggt atctggccgt tgccaaagaa aagtggactt ccacagctat cgttactcaa
    18361 cctgatgtgg gacaaatcgc tggttatacc aacgcgatga atgtgattta cggtccggct
    18421 gtaccgaaag tctccgacat tcagacttca cttatcggac gttacagcac tgcattctca
    18481 gcattagcgg aaacgttgga taatcaggaa gaacctgaaa aactgaccat tgagcctact
    18541 gttaaaaatc agtccttacc tttagcggtt tcttatgttg gtgaaacagc tgaaggtgcg
    18601 cagaaacagc tggcgcaata tatccagcaa gttgacgacc aggtaaacga agaactggaa
    18661 aaagacctga aagacaacat cgcgctgcgt atgaaaaact tgcaggattc gctgaaaacc
    18721 caggaagtag tcgcgcagga gcagaaagat ctgcgtatcc gtcagattca ggaagcgttg
    18781 cagtatgcga atcaggcgca ggtgacaaag ccacaggttc agcagactga agatgtgaca
    18841 caagatacgt tgttcctttt ggggagcgaa gcgctggagt cgatgattaa gcatgaggcg
    18901 acccgtccgt tggttttctc atcaaactac tatcagacac gtcaaaacct gctggatatc
    18961 gaaagcttaa aggttgatga tcttgatatt catgcttacc gctatgtaat gaaaccgacg
    19021 ttacctattc gtcgcgatag cccgaaaaag gcaattacct tgattttggc ggtgctgctg
    19081 ggcggcatgg ttggcgcggg gattgtgctg gggcgtaatg ctctacgcaa ttacaacgcg
    19141 aaataatctt tgcagcttta aagaaaacgg gcagggtggt gacactttgc ccgttttttt
    19201 ttgccggatg cgacaacaac atcgcatccg cttaccccgc cactcactga tgccgtttac
    19261 gcaggttctc aatcaccgtc gttaaatcca gatcctgatc ctgcaacaac accagcaggt
    19321 gatacatcaa gtcagatgcc tcgttggtca gctcaaagcg gtcatgtacc gttgcagcca
    19381 gtgcggtttc cacgccttct tcgcccactt tctgtgcaat gcgtttggtg ccgctggcat
    19441 acagtttggc ggtgtaagag gtttccgggt cggcagattt gcgttcggcg agcagttgtt
    19501 ccagttgata caggaacagc cactggtgag cggtgtcgcc gaagcagctg ctggtgcctt
    19561 tgtggcaggt cgggccgatg ggattcgcca gcaacagtaa cgtgtcgttg tcgcagtccg
    19621 gcgtaatatt tactacgttg tggaaattgc ccgacgtttc gcctttggtc catagtcgct
    19681 gtttagtgcg cgagaagaag gtgactttgc cgctttcgat ggttttgtct aaggcttccg
    19741 ggttcatata gcccagcatt agcacttcgc cggataccgc atgttgcaca attaccggca
    19801 tcagtccgtc ggttttttcc cagtccagtt cgcgacgttg ttgttctgtt aacatatcct
    19861 gatctccacg ccctgtgttg ccaggtacgc ttttaattca ccaatattga ttatttgttt
    19921 gtggaatacg gaagctgcca gcgcgccgtc aacgtcggca tcgcggaagg cttcgaggaa
    19981 gtgttccatg gtccccgcgc caccggaggc aattagcggg acgtggcaaa cttcacgcac
    20041 ttttttcagt tgttcgaggt cgtaaccgtt acgcacgccg tcctgattca tcatgttgag
    20101 gacgatttct ccggcaccgc gtttttgcac ttcctgtacc cagtcgagcg tttcccactg
    20161 agtgacgcgg gtgcggcttt catc
//
