LOCUS       AB812071               18684 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli genes for O-antigen biosynthetic locus, partial
            sequence, strain: 244-54.
ACCESSION   AB812071
VERSION     AB812071.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 18684)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..18684
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="244-54"
                     /db_xref="taxon:562"
                     /note="serogroup:O171"
     gene            <1..212
                     /gene="wcaM"
     CDS             <1..212
                     /gene="wcaM"
                     /codon_start=3
                     /transl_table=11
                     /product="colanic acid biosynthesis protein"
                     /protein_id="BAQ01885.1"
                     /translation="SSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNEKGQSS
                     VDIDRINHHIVNVEKINFRLPERRE"
     gene            370..1365
                     /gene="gne"
     CDS             370..1365
                     /gene="gnu"
                     /note="O171_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4-epimerase"
                     /protein_id="BAQ01886.1"
                     /translation="MNDNVLLIGASGFVGTRLLETAIADFNIKNLDKQQSHFYPEITQ
                     IGDVRDQQALDQALAGFDTVVLLAAEHRDDVSPTSLYYDVNVQGTRNVLAAMEKNGVK
                     NIIFTSSVAVYGLNKHNPDENHPHDPFNHYGKSKWQAEEVLREWYNKAPTERSLTIIR
                     PTVIFGERNRGNVYNLLKQIAGGKFMMVGAGTNYKSMAYVGNIVEFIKYKLKNVAAGY
                     EVYNYVDKPDLNMNQLVAEVEQSLNKKIPSMHLPYPLGMLGGYCFDILSKITGKKYAV
                     SSVRVKKFCATTQFDATKVHSSGFVAPYTLSQGLDRTLQYEFVHAKKDDITFVSE"
     gene            1608..2501
                     /gene="galF"
     CDS             1608..2501
                     /gene="galF"
                     /note="O171_02"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ01887.1"
                     /translation="MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNV
                     RQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRS
                     QVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLS
                     ADIWPELEHTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFRKGIEKLLSE"
     gene            2862..3482
                     /gene="nnaD"
     CDS             2862..3482
                     /gene="nnaD"
                     /note="O171_03"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="BAQ01888.1"
                     /translation="MKKKLIIIGAGGFAKAVIDSLDHNEYALEGFVDSLKSGMHQGYP
                     IVGHSLSDISLPTEYYYFIAIGDPDDRALWLSQIRDLKLETINVIDKTAIVSTRSSIG
                     TCIYIGKMAIVNCDSQLEDGVVINTRALIEHGNHISYCTNISTNVVLNGDVYVGEKSF
                     IGSCTVVNGQIKIGSSTIVGSGSVVIRNIPNNVVVAGTPTRLIRER"
     gene            3487..4527
                     /gene="nnaB"
     CDS             3487..4527
                     /gene="nnaB"
                     /note="O171_04"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="BAQ01889.1"
                     /translation="MSKIYIVAEIGCNHNGDFNLAKKMVEEAKKAGVDAVKFQTFKAD
                     QLISKYAPKAEYQIKVTGNQESQLEMTRKLELPYEEFIKLEEYAKELGLDVFSTPFDF
                     ESIDFLASRNQKMWKIPSGELLNLPYLEKISRLPIEGKEIVLSTGMATIEEIKASVNV
                     LTKNGMAPEKITILHCNTEYPTPYEDVNLNSIIGLKNEFKGYNVGFSDHSPGYYAAIA
                     SVPYGITFIEKHFTLNKDFEGPDHKASVTPDELCLLCEGIRAVEKSLGSHIKIVTKSE
                     QKNKIVARKSIVAKRNIKKGEIFTIDNITTKRPGNGISPMHWYDILGKKAEKDFEEDQ
                     LIKYSGFKEQEV"
     gene            4531..5796
                     /gene="nnaC"
     CDS             4531..5796
                     /gene="nnaC"
                     /note="O171_05"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acylneuraminate cytidylyltransferase"
                     /protein_id="BAQ01890.1"
                     /translation="MSRKKIAIIPARAGSKGLPDKNVLMLLDRPLIAYTIEAAVSSNL
                     FDKVIVSTDSERYKTIAEYYGAEVMLRSAELSSDTATSYMVIEDVLKNNPGYEIIALL
                     QPTSPFRTANHIIQSMELFEETDYARFLVSVSECFASTDLIKPLAQNGSLENFDKDFS
                     NYRRQNCRQYSPNGAIFLAYVSDYLEQKHFFGNKSVAFIMNKEDSIDIDDHLDFCTAI
                     AIQSNKSKINSIQNIIHQRINEKKEKFELCYPITLIGHSIFDYWDIECLNGQRVNNLG
                     IAGINSEQYYTLILESGLIKSIGNIILLMTGTNDLLNENWTPNYTLYWINKTIHFILH
                     NNPNAHIYFLATPPVRDRIDRSNSSIKYLNKILEENIKHTPCVTWVPLCDDFYDEFDY
                     LKIEFTTDGVHFNKIAYQYLENYIKGIIK"
     gene            5793..6947
                     /gene="nnaA"
     CDS             5793..6947
                     /gene="nnaA"
                     /note="O171_06"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetyl-D-glucosamine 2-epimerase"
                     /protein_id="BAQ01891.1"
                     /translation="MKKILYVTGSRAEYGIVKRLLAALKNDQDIELTIIATGMHCDEK
                     YGLTYKQIEKDGFVIEQLINININTLTNSDIINSMSVCQQKFGHYFQNNKFDAVMLLG
                     DRYEIFAVAVAAAIHNLPIIHIHGGEKTLGNYDEFIRHSITKMARLHLASTEQYRKRI
                     IQMGECPNSVVNIGALGAENALLMDLPSKSELEKKYGALTQPYFIVVFHPETLSQTST
                     TKQISELLTALRELTESYNFIFIGSNSDTGSDEIMKEILRFCQLTNSRLFKSVKPEEY
                     LALNKYSQGLIGNSSSGLIEIPSLLVPTINIGNRQKGRVRGTTVIDCACSAETIKSAI
                     LLSQGADFQRSLQFAENPYYKKAVLESAVNVIKSFVFNEKEHYKDFYDLD"
     CDS             7470..8123
                     /note="O171_07; transposse of ISAs1 family"
                     /gene="ISAs1"
                     /pseudogene="unknown"
                     /codon_start=1
                     /transl_table=11
     gene            8328..9593
                     /gene="wzx"
     CDS             8328..9593
                     /gene="wzx"
                     /note="O171_08"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAQ01892.1"
                     /translation="MLCLISMPELNYNSLYLSKVDVFMNKKNASHIGIFFLGEMLSKV
                     LPFLLLPFLTRYLPASDFGRLGYFMSLMGMGLIAVNWSFDGAIARYYYRYGKFNILNV
                     YYTAIVLSLALTFVLCLVASFFNNSIYLYAVVCAFLQGVFNILSTFQQCQKNAFKYIA
                     IQFTFSIISTALTIVLVLKWHADIDSRIVAILVGLSCAIFIGMKFLHVYRKIHVKDII
                     KKLNFTYLLSFGLPLIFHQISLMIKGQLDRIIIATTFDYVQLAHYTAGYQVASVISVG
                     IMAVNKAIVPTYYEACKSNKINKNKIYFLFWLLLPICLLPSIITYFIPPVFFVALLGE
                     KYEFIGTYVTIFTFGFMLQIPYLLLVNYLFYLNKTRVIAKITILSSIVHIVSIYILKS
                     YGIVYIPWALVLSNVFCIFLLYFYMGRKD"
     CDS             9593..10543
                     /note="O171_09"
                     /gene="weuD"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01893.1"
                     /translation="MNVFICFTPFQLFLSLEIVKLENLPPSRCIFFLYNYHDRFKVKK
                     NYIEVTKGFEQVYYESRPLTLAFIFKLRSIAKQIGQVKTAYLASIDNNIAHYLLSFLK
                     PLSIRTFDDGTANITQMSLFYRDIKTNPLKAALHLLLGKKYNREKIKSASDLHYTVYR
                     GVNNITDKIEILEMLRENTSDVENRKVLKIMLGSIYSELVDCSEDEVYIQNYIHRQCI
                     DEEMLYIPHPREDLSRINVPFVSDWRISEQIIVDFISCGYEVYLYGFPSSTFFNLSSN
                     AHVKCCIFMTDKLREEFKDLIKIAKSLNMSITNIPTGSFK"
     gene            10540..11691
                     /gene="wzy"
     CDS             10540..11691
                     /gene="wzy"
                     /note="O171_10"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAQ01894.1"
                     /translation="MIPHHNLICSFKLRLQIFFTLFTLYCIFSLWGMSVENKIFTYIS
                     LFISFLIVIFALTQGIRSVSFFILFAAFFCLSSMALFSNKTGEPVAILINAYLFVFAM
                     MISNIIYKLRLACRSSVILFSTTHIYFFIFCIYKYKIDGFINENTFNELFWQSSRNIV
                     SAILLLATIFFLAVNYIEQKKIYLSVLFINMISSILLYGRSGVVLSFIVLFIGIYLKF
                     FKEEKNVIKIILFLFFSILILVLILYTGFTDNMVSAILSHTNLQSGFDTPRIQMWYDY
                     IVNFDYKILLLGTNFLFSPLITSFDGNPHNSFIMFQARFGIFAVLFLLSISYLYLKLF
                     QNSLLLSLLLGLIFVRMFFDTFSLFGYFDFIWVYMLIYLPRNNKKRSFL"
     CDS             11688..12650
                     /note="O171_11"
                     /gene="wfeS"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01895.1"
                     /translation="MRVILTLIIPVYNVEAYIEECLESLFPQIANSKNNDVEVIIVND
                     GTPDKSMDIVIHAIKKYSLERQVRVVNQCNQGLSAARNTGIRLATGDYIGFIDSDDYV
                     SENYIREIKSNILKYYQLDILKFNFHFFRNKVSRSRRTNLINTVRYSGTEYIKNDIKE
                     NSWYAWRRIYASHLFDDILFDVGKKYEDVLTVPLLTFKSSNCVALNSTLVFYRSNPYG
                     ITKNSELEHAIDILSRVNDHVEIMKRRGYNKQLISLHVYNIAKTFVNTVATAWKGKFD
                     IFFIHSNFTTIYPHLNVFRTVYVYVYYFKAVLKYLLSQVKRKIL"
     CDS             12647..13522
                     /note="O171_12"
                     /gene="wccM"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01896.1"
                     /translation="MKTSVIITTKNRPQLFREALRSVYNQTVKPDEIIVIDDASSLDY
                     DVFFDTQKIPIIHHKLDTSLGVANARNVGVSLASCDVIFFLDDDDIWNNNHIDSHLRC
                     HYNPDIVMCFSKKELFFCSENNIIRTTKNIEPIESNILSENYIGTPSGVSIKRKYLGG
                     DCIFDVNLPALEDYDLWLQLILKVGNEKIHFVDIPTVKYRISSPKKTNVSHNLRNHEI
                     ARIRIIKKNQGKLTCQELKIIDKYLRFCLLKTAHRNSYYRMIRLLFKYPVFTMKTIVL
                     LIPYSLLNLFGVYSS"
     CDS             13533..14351
                     /note="O171_13"
                     /gene="wbwC"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01897.1"
                     /translation="MMKFSVLMSLYDKEQPEFLNDCLTSLARQSVMPTEIVIVYDGYV
                     NNALKKVVNSYLSILPIKILQLPNNIGLGLALNQGLKYCAYDYVARMDTDDICVDNRF
                     ERQVAHIIQHPELSICGGGISEYDLTLTHFLGNRDVPKCHSEIKKYITMRNPFNHMTV
                     MFKKNDVLSVGGYVHHDLMEDYNLWIRMLSKGFKASNLDGILVHARTGNAMLCRRKGW
                     RYIKSEFYLAKVKIEYNIQSVPYAYFIMVARVVPRLLPTKFLSLFYRITRKTKL"
     gene            14458..15864
                     /gene="gnd"
     CDS             14458..15864
                     /gene="gnd"
                     /note="O171_14"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ01898.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKEQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKEIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            16110..17276
                     /gene="ugd"
     CDS             16110..17276
                     /gene="ugd"
                     /note="O171_15"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ01899.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDKINFNATLDKNEAYRDAGYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVAINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNILTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            17366..18400
                     /gene="wzz"
     CDS             17366..18400
                     /gene="wzz"
                     /note="O171_16"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ01900.1"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLV
                     QLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGP
                     AVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQSLPLAVSYVGETA
                     EGAQKQLAKYIQQVDDQVNEELEKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQ
                     IQEALQYANQAQVTKPQVQQTEDVTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQT
                     RQNLLDIESLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLG
                     RNALRNYNAK"
     gene            complement(18498..>18669)
                     /gene="hisI"
     CDS             complement(18498..>18669)
                     /gene="hisI"
                     /codon_start=2
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ01901.1"
                     /translation="QKVGEEGVETALAATVHDRFELTNEASDLMYHLLVLLQDQDLDL
                     TTVIENLRKRHQ"
BASE COUNT     5870 a   3198 c   3778 g   5838 t
ORIGIN
        1 aatcctctgt tggaccagca ttgagcatga actttgacat gcgcaaagac gttcgcggcg
       61 tctttatggc gaaaaaagaa acactgctgt ctcttgcaaa tgttcatgcg gtgaatgaaa
      121 aagggcaaag ctccgtcgat atcgacagga taaatcacca tattgttaat gtggaaaaga
      181 ttaactttag attgccggaa cggagggagt agatttgcga ccattcataa acttactgga
      241 tataatgttc taaaagatta taatcctcac actaactgtt aaagctgggg ctgggcagca
      301 ttgactactc agggaaggta ctcatcttta tcttgtgttt cttacgtaac aaccagacta
      361 aagtgattta tgaacgataa cgttttgctc ataggagctt ccggattcgt aggaacccga
      421 ctacttgaaa cggcaattgc tgactttaat atcaagaacc tggacaaaca gcagagccac
      481 ttttatccag aaatcacaca gattggcgat gttcgtgatc aacaggcact cgaccaggcg
      541 ttagccggtt ttgacactgt tgtgctactg gcagcggaac accgcgatga cgtcagccct
      601 acttctctct attatgatgt caacgttcag ggtacccgca atgttctggc ggccatggaa
      661 aaaaatggcg ttaaaaatat catctttacc agttccgttg ctgtttatgg tttgaacaaa
      721 cacaaccctg acgaaaacca tccgcacgat cctttcaacc actacggcaa aagtaagtgg
      781 caggcagagg aagtgctgcg tgaatggtat aacaaagcac caacagaacg ttcattaacc
      841 atcatccgtc ctaccgttat cttcggtgaa cgaaaccgcg gtaacgtcta taacttgctg
      901 aaacagatcg ctggcggcaa gtttatgatg gtgggcgcag ggactaacta taagtccatg
      961 gcttatgttg gaaacattgt tgagtttatc aagtacaaac tgaagaatgt tgccgcaggt
     1021 tatgaggttt ataactacgt tgataagcca gatctgaaca tgaaccagtt ggttgctgaa
     1081 gttgaacaaa gcctgaacaa aaagatccct tctatgcact tgccttaccc actaggaatg
     1141 ctgggtggat attgctttga tatcctgagc aaaattacgg gcaaaaaata cgctgtcagc
     1201 tctgtgcgcg tgaaaaaatt ctgcgcaaca acacagtttg acgcaacgaa agtgcattct
     1261 tcaggttttg tggcaccgta tacgctgtcg caaggtctgg atcgaactct gcagtatgaa
     1321 ttcgtccatg ccaaaaaaga cgacataacg tttgtttctg agtaatgcag acgagtcaga
     1381 gaaaaaagga ccaggttgga ctacgattat tcggaaagag gtactgatta aattatcagt
     1441 atgcggaatt ccgagtaatc cgagtaaccc agatgctgat ggtgtgtagt gttatcgcaa
     1501 ggtttaatca aagttatgcg gaactaagct ttggtatata gccataccgt ttggctaatc
     1561 tatggcaata atttacgcac tatcagccac ttagaggtag gaaaataatg acgaatttaa
     1621 aagcagttat accggtagcg ggtcttggga tgcatatgtt gcctgccact aaggcgatac
     1681 ccaaagagat gctaccgatc gtcgacaagc caatgattca gtacattgtt gacgagattg
     1741 tggctgcagg gatcaaagaa atcctcctgg taactcatgc gtccaagaac gcggtcgaaa
     1801 accacttcga cacctcttat gaattagaat ctcttcttga acaacgtgtg aagcgtcaac
     1861 tgttggcgga agtacagtcg atctgcccgc cgggcgtaac cattatgaac gtgcgtcagg
     1921 gcgaaccttt aggtttgggc cactccattt tatgtgcacg acccgccatt ggtgacaatc
     1981 catttgtcgt ggtgctgcca gacgttgtga tcgacgacgc cagcgccgac ccgctgcgct
     2041 acaaccttgc agccatgatt gcgcgcttca acgaaacggg acgcagccag gtactggcaa
     2101 aacgtatgcc gggtgacctc tctgaatact ccgtcatcca gaccaaagaa ccgctggacc
     2161 gtgaaggcaa agtcagccgc attgttgaat ttatcgaaaa accggatcag ccgcagacgc
     2221 tggactcaga catcatggcc gtaggtcgtt atgtgctttc tgccgatatt tggccggaac
     2281 ttgaacacac gcagccaggg gcatggggac gtattcagct gacagatgcc atcgctgaac
     2341 tggcgaaaaa acaatctgtt gatgcaatgc tgatgactgg tgacagctac gactgcggta
     2401 aaaaaatggg ctatatgcag gcgtttgtga agtatggctt acgcaacctg aaagaagggg
     2461 cgaagttccg taaagggatt gagaagctgt taagcgaata atgaaaatct gaccggatgt
     2521 aacggttgat aagaaaatta taacggcggt gaagattcgt ggcgaaagta atttgttgcg
     2581 aatattcctg ccgttgtttt atatgaacca tcagaataac aacgagttag caataggatt
     2641 ttagtcaaag ttttccagga ttttccttgt ttccagagcg gattggtaag acaattagaa
     2701 tatcttcttt taaagtttta aaataattta aaaggattct aatttcaaaa aataaatctc
     2761 tacagtgcac tggtagctgt taagcctggg gcggtagcgt gtctgataat gccctcactg
     2821 gaaggcgaat tcaaatgcta aacttcactt atggtgcgtg aatgaagaaa aaattgatca
     2881 taatcggggc tggtgggttt gctaaagcag taatagatag tctggatcat aatgaatacg
     2941 ctcttgaagg gtttgttgat tcactgaaat ccggaatgca tcaaggatat cctatcgttg
     3001 gtcattcatt aagtgatatt agtttgccaa ctgagtacta ttattttatt gccattggtg
     3061 atcctgatga tagagcatta tggttaagtc aaatacgaga tctaaagctt gaaacgataa
     3121 atgtcattga taaaacagca attgtatcaa caagatcttc aatcggaaca tgtatttaca
     3181 ttgggaaaat ggctatagta aattgtgatt cacaattaga ggatggagtc gtaattaata
     3241 ctagagcctt gatagaacat gggaatcata tttcatattg tacgaatatt tcaactaatg
     3301 tggtccttaa tggtgatgta tatgttggag agaaaagttt tataggtagt tgtactgttg
     3361 taaatgggca aataaaaata ggaagctcga caattgttgg atctggatca gtagtaatac
     3421 gaaacatccc taacaatgtt gttgttgcag gaacaccaac aagattaata agagaaaggt
     3481 aagcaaatga gtaaaatata tattgtggct gaaattggat gtaatcataa tggtgatttt
     3541 aatcttgcaa aaaaaatggt tgaagaagcc aaaaaagctg gtgttgatgc agtcaaattt
     3601 cagactttta aagctgatca attaatttcg aaatacgcac ctaaggcaga gtatcagata
     3661 aaagtaactg gtaatcagga atcccaatta gaaatgacaa ggaagcttga gctgccttat
     3721 gaagagttta taaagcttga agaatatgca aaagagttag gacttgatgt cttttcaaca
     3781 ccatttgatt ttgaatctat cgattttctt gcttcaagaa atcaaaaaat gtggaaaata
     3841 ccttcaggtg aattgcttaa tctcccgtat cttgaaaaaa taagcagatt gccgattgag
     3901 ggaaaagaga ttgtattgtc tacaggaatg gccacaattg aagaaatcaa agcaagtgta
     3961 aatgttctta ctaaaaatgg aatggctcct gaaaagatca caatattaca ttgtaacact
     4021 gaatatccta caccatatga agatgtaaat ttaaactcaa ttattggtct aaagaatgaa
     4081 tttaaaggat ataacgttgg cttttctgac cattcacctg gttattatgc agctattgca
     4141 tcagttccgt atggaattac attcatcgaa aaacatttta ctctaaataa agattttgaa
     4201 gggcctgatc ataaggcatc agttacacca gacgagttgt gcctattgtg tgagggaatc
     4261 cgtgcagtag aaaaatcttt ggggagtcat atcaaaatag taacgaaatc tgaacagaaa
     4321 aataaaattg tagctagaaa gtccatcgtt gcaaaacgta atattaaaaa gggtgagata
     4381 tttactattg ataatatcac tacaaaacga ccaggaaatg gaattagccc aatgcattgg
     4441 tatgatatat tggggaaaaa ggcagaaaaa gattttgagg aagatcaatt gattaagtat
     4501 agtggtttta aagaacaaga ggtttaattt gtgtcaagaa agaaaatcgc tataatacct
     4561 gcacgagcgg gctctaaggg tttgccagat aagaatgttt taatgcttct agatcgtccg
     4621 ttaattgcgt atacaattga agccgcggtg agttctaatt tatttgataa agttatagta
     4681 tccaccgatt cagaaagata taaaacgata gcagagtact atggtgcaga agtcatgcta
     4741 cgtagtgcag aattatcttc tgatacagca acatcttata tggtaattga ggatgtttta
     4801 aaaaataatc caggctatga gattattgca ttacttcaac caacgtcacc gttccggact
     4861 gcaaatcata ttatacaatc aatggagtta tttgaagaaa cagattatgc gagatttcta
     4921 gtatcggtat cggaatgttt tgcaagtact gatttaatta agcctcttgc gcagaatggg
     4981 agtctagaaa attttgacaa agattttagt aattatcgtc gtcaaaattg cagacaatat
     5041 tcaccgaatg gggccatatt tttagcatac gtatcagact atttagagca aaaacatttt
     5101 tttggaaata aaagtgtcgc gtttattatg aataaagagg attctataga tatagacgac
     5161 catttagact tttgtactgc gattgcgata caatctaata aatcaaaaat aaattcaatt
     5221 cagaatatta ttcatcagcg tataaatgaa aaaaaagaaa agttcgaatt atgttatcca
     5281 ataacgctga ttggacattc aatctttgat tactgggata ttgaatgttt aaatggccaa
     5341 agagtcaata atttgggcat tgctgggatt aactcagaac aatattatac attaatacta
     5401 gagtctggat taataaaatc aattggtaat ataattttat taatgactgg aacgaatgat
     5461 ctcctcaatg aaaattggac accaaattat actctatatt ggataaataa aactattcac
     5521 tttattttac ataataaccc caatgcacat atttattttt tagcaactcc accagttaga
     5581 gacagaatag atagatccaa tagttcaata aaatacctta acaaaatttt agaagagaac
     5641 attaaacata ccccttgtgt tacatgggta ccattgtgtg atgattttta tgacgaattt
     5701 gattatttaa aaattgagtt tacaactgat ggggtgcatt ttaataaaat cgcatatcag
     5761 tacctagaga attatattaa aggaattatc aaatgaaaaa aatattatat gttacaggtt
     5821 cacgagctga atatgggatt gtgaaacgat tgttagcggc tttaaaaaat gatcaggata
     5881 tagagcttac aattattgca acaggaatgc attgtgacga gaaatatggt ttaacttata
     5941 aacaaattga aaaggatggt tttgttattg aacagctaat taatattaat attaatacgc
     6001 taacgaactc cgatataatt aactcaatgt ctgtatgtca acaaaaattt ggtcactatt
     6061 ttcaaaataa taaattcgat gctgtgatgc tgcttggtga tcgctatgaa atatttgcag
     6121 ttgcagttgc tgctgcgatt cataatctac ctataattca cattcatggc ggtgaaaaaa
     6181 cattaggcaa ttatgatgag tttattaggc attcaataac caaaatggca cgtttacatt
     6241 tagcctcgac agagcaatat cgtaaaagaa taattcaaat gggggagtgc ccgaatagtg
     6301 ttgttaatat aggagcatta ggagcggaaa atgcattact tatggactta cccagtaaga
     6361 gtgaattaga gaaaaaatat ggtgccttaa cacaaccgta ttttattgtt gtttttcacc
     6421 ctgaaacatt aagccaaaca tctacaacca agcaaataag tgagttatta actgctttgc
     6481 gagaattaac tgaaagttac aattttatat tcattggctc taattctgac actggttctg
     6541 atgagataat gaaggagatt ttaaggtttt gccaactcac taactctagg ctcttcaaat
     6601 cagtaaaacc agaagaatat cttgccctta ataaatattc gcagggttta ataggtaatt
     6661 cgtcatcggg acttattgaa ataccatctt tattggtacc gacgattaat atcgggaata
     6721 gacaaaaagg aagagttcgt ggcacaacag taattgattg tgcatgttct gcagaaacta
     6781 ttaaaagtgc tattctttta agtcaaggag ctgattttca acgttcatta cagttcgcag
     6841 aaaatccata ttataaaaag gcagtcttag aatccgctgt aaatgtaatt aaatcatttg
     6901 tctttaatga aaaggagcac tacaaagatt tttatgatct cgattagtac tattcctact
     6961 agatgtgttg ggttaaaaat cattaaagtg gggatatttc agagtataaa gagtgtgata
     7021 ttatcaggca taaatttacc agaagtacac ttttgtacca aggcaagatc acgtaacgct
     7081 gattttttgt actaaatgat tcgcatttta tgtttaaata ttgagatatt cctcattacc
     7141 taaagctttt ttttattgct tatacatgat caaatactcc ttacataatt aaggaggact
     7201 aaaaaatcga tggaacatat ttctattatt cccgattaca gacaagcctg gaaagtggaa
     7261 cattaattgt cagatattct actgttgact attcgcgtcg ttatttctgg tgcagaaggt
     7321 tgggaagata tagaggattt tggggaaaca catcgcgatt ttttgaagca atatggtgat
     7381 tttgaaaatg gtattcctgt tcacgatacc attgccagag tgtatcctgt atcagccctg
     7441 caaaatttca cgagtgcttt attaactgga tgcgtgattg tcattcttca ggagataaag
     7501 acgtcattgc aattgatgga aaaacgctcc ggcactctta tgacaagagt cgccgcaggg
     7561 gagcgattca tgtcattagt gcgttctcaa caatgcacac tctggtcatc ggacagatca
     7621 agacggatga gaaatctaat gagattacaa ctatccctga actgattaac atattggata
     7681 ttaaaggaaa aattatcaca actgatgcga tgggttgcca gaaagatatt gcagagaaga
     7741 tacaaaaaca gggaggtgat tatttattcg ctgtaaaagg aaaccagggg cggcaaaata
     7801 aagcctttga ggaaagattt ccgctgaaag aattaaataa tacaaagcat gacagttacg
     7861 caattagtga aaagagtcac ggcagagaag aaatccgcct tcatattgtt tgcggtgtcc
     7921 ctgatgaact tattgatttc acgtttgaat ggaaaggatt gaaaaaatta tgcgtggcag
     7981 tctcttttcg gtcaataata gcagaaaaaa agaaagagcc cgaaatgacg gacagatatt
     8041 atatcagttc tgctgattta accgcaaaga agttcgccac agcgatccta aatcactggc
     8101 tcgtggagaa taagttgcac tgacgtctga acgaggtaat gaatgaagac gactgcaaaa
     8161 taagaagaga aaacgcagaa gaactatttt tagtgatacg gcatattgct attaatattt
     8221 taacgagcga taagtattaa ggcggggtta agacgtaaga tgagaaaagc agctatggat
     8281 agagacttca tcgcttcagt ctttgtggag aactggcatt cagaatcttg ctctgtttaa
     8341 tctctatgcc cgagctgaat tataatagtt tatatttgtc aaaagtggat gtgtttatga
     8401 ataaaaaaaa tgcttcacat atagggattt tttttttagg tgaaatgctt tctaaggtat
     8461 tgccatttct gttattacct tttctcacaa gatatctacc tgcttctgat tttgggcgtt
     8521 taggatactt tatgtcttta atgggaatgg ggctaatagc tgttaactgg agttttgacg
     8581 gtgcaattgc gagatattat tatcgttatg ggaaatttaa tatattaaat gtttattata
     8641 ctgcgattgt tctatcctta gcattaacat ttgtattgtg tctggtggca agttttttta
     8701 ataatagcat atatttatat gcagtagttt gcgcattttt acaaggagta ttcaatatat
     8761 taagtacatt tcaacaatgt caaaaaaatg cttttaaata tattgcaatt cagtttacat
     8821 tttcaataat ttcaactgct ttaacaatag ttttagtgct caagtggcat gcagatattg
     8881 attcgcgaat agttgctata cttgtggggt tatcatgtgc aatttttata ggtatgaaat
     8941 ttttgcatgt ttatagaaaa atacatgtta aagatataat taagaaatta aattttacat
     9001 atctattatc atttgggtta ccattaatat ttcatcagat tagcttaatg attaaagggc
     9061 agttagatag gattatcatc gcaactacgt ttgattatgt tcaattagcg cattatactg
     9121 ctggatatca ggttgcaagt gtaatttcag taggtattat ggcagttaat aaggcaattg
     9181 tccctacata ttatgaagcc tgcaagagta ataaaataaa taaaaataaa atatattttt
     9241 tattctggct tctattacca atttgtcttc tccctagcat aattacatat ttcattcctc
     9301 ctgttttttt cgtggcatta ttaggagaga aatatgagtt cattggcaca tatgtaacaa
     9361 tatttacatt cggttttatg ttgcagatcc catatttatt gttggttaat tatttatttt
     9421 atctaaataa aacacgagtt attgcaaaaa taacaatatt gagtagtata gtgcatatag
     9481 tatcaattta tatacttaag tcttatggga tagtttatat tccatgggcc ttggttttat
     9541 caaatgtctt ctgtattttt cttttgtatt tttatatggg aagaaaagac taatgaatgt
     9601 ttttatttgt tttacaccct tccaactttt tttgtcatta gagattgtaa aactcgaaaa
     9661 tctccccccc agtagatgca ttttttttct ttataattat catgatcgat ttaaagttaa
     9721 aaaaaattat attgaagtaa ctaagggttt tgaacaggtt tattatgagt ctcgaccgtt
     9781 aactctggca tttatattta aacttcgttc tattgcaaaa caaattggcc aagttaaaac
     9841 cgcttacctt gcaagtattg ataacaatat agctcattat ttattgtctt ttttaaagcc
     9901 actttcaatt agaacatttg atgatggtac tgctaatatt actcaaatga gtttgtttta
     9961 cagggatatt aaaaccaatc cactaaaagc tgccttgcac ttattattag ggaagaaata
    10021 taatcgtgaa aaaataaaat cggcctcaga tttacactat acagtgtaca gaggggttaa
    10081 taatatcaca gataaaatag aaatactgga aatgctgcgg gaaaacacta gtgatgtgga
    10141 aaaccggaag gtattaaaaa ttatgctagg ttcaatatat agtgaattgg ttgattgttc
    10201 tgaagatgaa gtttatattc agaattacat ccataggcaa tgtattgatg aagagatgtt
    10261 atatattcct catccacgtg aagatttaag ccgtataaat gttccattcg tttcggactg
    10321 gaggatttca gaacaaatta tcgttgattt tataagttgc gggtatgaag tttatttata
    10381 cgggtttcct agttcaacat tttttaattt aagcagtaat gctcatgtaa aatgttgtat
    10441 ttttatgact gataagttaa gagaagagtt taaagatctt attaaaattg caaaatcttt
    10501 gaatatgtct attacaaata ttcccacagg aagctttaaa tgatacctca tcataatctt
    10561 atttgttcat ttaagctaag attacaaatc tttttcactc tttttacgct ttattgtata
    10621 ttttctttat ggggtatgag tgttgaaaat aaaattttta catatatatc gttatttata
    10681 tcatttctta tagttatttt cgcgttgacc caagggatca gaagtgtttc attttttatt
    10741 ttatttgccg catttttttg tttatcgtca atggctctct ttagtaataa aactggtgag
    10801 cctgttgcta ttcttatcaa tgcatatctt tttgtttttg caatgatgat aagcaatatt
    10861 atttataaac tacgtcttgc atgtcgtagt tcagttatat tattttccac tacacatatt
    10921 tatttcttta ttttttgcat ctataaatat aaaattgatg gattcattaa tgaaaatact
    10981 ttcaatgaac tgttttggca aagtagtcgt aatatagttt ctgctatttt acttcttgcc
    11041 actattttct tcttggccgt gaattatatt gagcaaaaaa aaatctatct tagtgtgtta
    11101 tttatcaata tgataagctc aatattattg tatggcagaa gcggtgtggt tctgtctttt
    11161 attgtgttgt ttattgggat atatctaaaa ttctttaaag aagaaaaaaa tgtcataaaa
    11221 attattttgt ttttattctt ttcaatcctc atcttagtgt tgattttata tactggattc
    11281 acagataata tggtcagcgc tatattatct catacaaatc ttcaatcagg atttgatacc
    11341 cctcggattc aaatgtggta tgattacatt gttaattttg attataaaat tctgttattg
    11401 ggtacaaact ttttatttag tccattgatt acatcttttg atgggaatcc acataactca
    11461 tttataatgt ttcaagctag atttggaata tttgcggtat tatttttatt gtctattagt
    11521 tatctatact tgaaactttt tcagaactct ttattgctgt cactgctttt aggattgata
    11581 ttcgttagaa tgttttttga tactttttct ctcttcggat attttgattt tatctgggtg
    11641 tatatgttga tctatctgcc gagaaacaat aaaaagagaa gttttttatg agagtgatac
    11701 ttactttgat tattccagta tataatgttg aagcttatat agaggaatgc ttggaaagtt
    11761 tatttccaca aatagccaat tctaaaaata atgatgtcga agtgattatt gtaaatgatg
    11821 gtacccctga taagtctatg gatatagtca ttcacgctat aaaaaaatat agcttggaac
    11881 gacaggttag agttgttaat cagtgtaatc aaggattaag tgccgctaga aatacaggga
    11941 taagattagc aactggtgat tatataggat ttattgattc tgatgattat gttagcgaga
    12001 attacattcg agaaatcaag tctaatatat taaaatatta tcagctggat atattaaagt
    12061 ttaattttca tttctttagg aataaagtct ccaggagtcg gcgaactaat ttaattaata
    12121 cggtccgata ctctgggact gagtatatta aaaatgatat caaagaaaat tcttggtatg
    12181 catggcgcag gatctatgct tcgcatttat tcgatgatat tctatttgac gttgggaaaa
    12241 aatatgaaga tgttttaact gttcctttgc ttacttttaa atcatcaaac tgtgttgctc
    12301 ttaatagtac tttagttttt tatagatcaa atccctatgg gataacaaaa aattcggagt
    12361 tagagcatgc aatcgatatc ttgtcgagag taaatgatca tgtcgagata atgaaacgac
    12421 gaggatataa taagcagctt atttctttgc acgtctataa tattgctaaa acatttgtca
    12481 atactgtagc aactgcttgg aaaggtaaat tcgacatttt ttttatacac tctaatttca
    12541 ctaccatcta tccacacctc aatgttttcc gaactgttta tgtctatgtt tactatttta
    12601 aagcagtttt gaagtatttg ctttcacaag ttaaaagaaa aatattatga agaccagtgt
    12661 cattattact acgaaaaata ggcctcagtt gtttagagaa gcactacgtt ctgtttataa
    12721 tcaaacagtc aagcctgatg agataattgt tatcgatgac gcatcttctc tcgattatga
    12781 cgtttttttc gatactcaaa aaataccgat aattcatcat aaattagata ctagtcttgg
    12841 agtggcaaat gcaagaaatg ttggtgtatc tttagcttcc tgtgatgtta ttttttttct
    12901 tgatgatgat gatatctgga ataataatca catagatagt cacttgcgat gtcattacaa
    12961 tccagatatt gtaatgtgtt tttcaaaaaa agaattgttt ttttgttcag aaaataatat
    13021 tataagaaca accaaaaata ttgagccaat agaatctaac atcctttctg aaaactatat
    13081 tggtactccc agtggtgttt ctatcaagcg aaaatatctt ggcggtgatt gcatatttga
    13141 tgttaattta cctgcattag aggattacga cctttggtta caattgattt taaaagttgg
    13201 caatgaaaaa attcatttcg ttgatattcc gacagtaaaa tatagaatat catcaccaaa
    13261 gaaaacaaat gttagtcata atctacgtaa ccacgaaatt gcgcgaatca ggataataaa
    13321 aaagaatcaa gggaagctta cttgtcagga attaaaaata atagataaat atcttcgatt
    13381 ttgtttacta aaaacagctc atagaaattc ctattataga atgattcgac ttctttttaa
    13441 gtatccggta tttacaatga aaactatagt tttgttaatt ccctattcgt tgttaaattt
    13501 attcggtgtt tattccagtt gagcaatgtt gaatgatgaa attttctgta ttaatgtctc
    13561 tttatgataa agaacaacct gagtttttga atgattgttt aactagttta gctagacaaa
    13621 gtgttatgcc taccgaaata gtcattgttt acgatggcta cgtcaataat gcattaaaga
    13681 aagttgtaaa tagttattta tccatcctac ctatcaaaat attgcaactt cctaataata
    13741 ttggtttagg cttggccctg aatcagggcc ttaaatattg cgcatatgat tatgttgccc
    13801 ggatggatac tgatgatatt tgtgtggata atcgctttga acgtcaagtc gctcatatta
    13861 tccaacaccc ggagctatct atttgtgggg gggggatttc tgaatatgat ttaaccttaa
    13921 ctcatttttt gggaaatcga gatgtcccta aatgtcattc tgaaataaaa aaatacataa
    13981 ctatgcgaaa tccattcaat catatgactg taatgtttaa aaaaaatgat gtcttgagtg
    14041 ttggtggata cgttcatcac gatttgatgg aggattataa cctttggata cgaatgttga
    14101 gtaaaggttt taaagcatct aatttagatg gtatcttggt gcacgctcgt acgggcaatg
    14161 caatgctgtg tcgtcgtaaa gggtggcgat atattaagag tgaattttat ttagcaaaag
    14221 tgaaaattga atataatatc caaagtgttc cttatgctta ctttattatg gttgctaggg
    14281 tggttcctcg attattacca acaaaattcc tctctctatt ttatcgtatc accagaaaaa
    14341 ccaagttata atagttattt attttagttc aaaataatag attttttctg agttaatata
    14401 tcaactgtat ttcaagccgc gcaccacaag cggtgacaca cctgacagga gtaaacaatg
    14461 tcaaagcaac agatcggcgt cgtcggtatg gcagtgatgg ggcgcaacct tgcgctcaac
    14521 atcgaaagcc gtggttatac cgtctctatt ttcaaccgtt cccgtgaaaa aacggaagaa
    14581 gtgattgccg aaaatccagg caaaaaactg gttccttact atacggtgaa agagtttgtt
    14641 gaatctctgg aaacgcctcg tcgcatcctg ttaatggtga aagcaggtgc aggcacggat
    14701 gctgctattg attccctcaa gccgtacctc gataaaggtg acatcatcat tgatggcggt
    14761 aacaccttct tccaggacac tattcgtcgt aaccgtgaac tttctgccga aggctttaac
    14821 ttcatcggta ccggtgtttc cggtggtgaa gagggcgcgc tgaaaggtcc ttccattatg
    14881 cctggtggcc agaaagaagc ctatgaactg gttgctccga tcctgaccaa aatcgccgca
    14941 gtagctgaag acggtgagcc atgcgttacc tatattggtg ccgatggcgc aggtcactat
    15001 gtgaagatgg ttcataacgg tattgaatac ggtgatatgc agctgattgc tgaagcctat
    15061 tctctgctta aaggtggcct gaacctcacc aacgaagaat tggcgcagac ctttaccgag
    15121 tggaataacg gtgaactgag cagctacctg atcgacatca ccaaagatat cttcaccaaa
    15181 aaagatgaag acggtaacta cctagttgat gtgatcctgg atgaagcggc taacaaaggt
    15241 accggcaaat ggaccagcca gagcgcgctg gatctcggcg aaccgctgtc gctgattact
    15301 gagtctgtgt ttgcacgtta tatctcttct ctgaaagagc agcgtgttgc cgcatctaaa
    15361 gttctctctg gcccgcaagc acagccagca ggcgacaagg ctgagttcat cgaaaaagtt
    15421 cgccgtgcac tgtatctggg caaaatcgtt tcttacgctc agggcttctc tcagctacgc
    15481 gccgcgtctg aagagtacaa ctgggatctg aactacggtg aaatcgcgaa gattttccgt
    15541 gctggctgca tcatccgtgc acagttcctg cagaaaatca ccgatgcata tgccgaaaat
    15601 ccgcagatcg ctaacctgct gctggctccg tacttcaagg aaattgccga tgactaccag
    15661 caggcgctgc gcgatgtcgt cgcttatgca gtacagaacg gtatcccggt tccgaccttc
    15721 gccgctgcgg ttgcctatta cgatagctac cgtgccgctg ttctgcctgc gaacctgatc
    15781 caggcacagc gtgactattt cggggcgcat acttataagc gcattgataa agaaggtgtg
    15841 ttccatactg agtggctgga ttaatctgat ttacccagca atattttgag gcccggcata
    15901 tattgccggg cttttttttg ccaattatct tatagactaa atttcactgc ttaatattaa
    15961 cttaataaat atcagctatt cttataaaga aaatctgaat tgtttttcgt tgcgttgacc
    16021 atcgaagaac gtagcgttaa aacttttagc tcttatcagg atgctaaaaa catcatgatt
    16081 catagttaag ttaattctga gagcatgaaa tgaaaattac catttccggt actggctatg
    16141 taggcttgtc aaacgggctt ctaatcgcac aaaatcatga ggttgtggca ttagatattt
    16201 taccgtcacg cgttgctatg ctgaatgatc ggatatctcc tattgttgat aaggaaattc
    16261 agcagttttt gcaatcagat aaaataaact ttaatgccac attagataaa aatgaagcct
    16321 accgggatgc tggttatgtc atcatcgcta ctccaaccga ctatgatcct aaaactaatt
    16381 atttcaatac atccagtgta gaatcagtaa ttaaagacgt agtagcgata aatccttatg
    16441 cggttatggt catcaaatca acggttcccg ttggttttac cgcagcgatg cataagaaat
    16501 atcgtactga aaatattatt ttctctccgg aattcctccg cgaaggtaaa gccctttacg
    16561 ataatctcca tccttcacgt attgtcattg gtgagcgttc agaacgcgca gaacgttttg
    16621 ctgcgttatt acaggaaggc gcgattaagc aaaatatcct gaccctgttt accgattcaa
    16681 ccgaagcaga agcgattaaa cttttcgcta atacctatct ggcgatgcgc gtagcatact
    16741 ttaatgaact ggatagctat gcagaaagtt taggtctgaa tactcgccag attatcgaag
    16801 gcgtttgtct cgatccgcgt attggcaacc attacaacaa tccgtcgttt ggttatggtg
    16861 gttattgtct gccgaaagat accaagcagt tattggcgaa ctaccagtct gtgccgaata
    16921 acctgatttc ggcaattgtc gatgctaacc gcacgcgtaa agactttatt gccgatgcca
    16981 ttttgtcacg caaaccgcaa gtggtgggta tttatcgtct gattatgaag agcgggtcag
    17041 ataacttccg tgcgtcttcc attcagggga ttatgaaacg tatcaaggcg aaaggcgttg
    17101 aagtgatcat ttacgaaccg gtgatgaaag aagactcgtt cttcaactct cggctggaac
    17161 gtgatctcgc cactttcaaa caacaagccg acgtcattat ctccaaccgt atggcagaag
    17221 agcttaagga tgtggcagac aaagtctaca cccgcgatct ttttggcagt gactaacatc
    17281 ctgttatcag ggcgattttc gccctgattc tcttatgttc cctttgtaat aattcattat
    17341 ttttatcatt tatcctatag cattcatggc gattatcgct aaactatggc gacttaaaat
    17401 tatttcgtcc gttagggtaa tgatgagagt agaaaataat aatgtttctg ggcaaaacca
    17461 tgacccggaa cagattgatt tgattgattt actggtgcag ttgtggcgcg gcaagatgac
    17521 aattatcatc tctgtcattg ttgctattgc cctggctata gggtatctgg ccgttgccaa
    17581 agaaaagtgg acttccacag ctatcgttac tcaacctgat gtggggcaaa tcgctggtta
    17641 taccaacgcg atgaatgtga tttacggtcc ggctgtaccg aaagtctccg acattcaggc
    17701 ttcacttatc ggacgttaca gcactgcatt ctcagcatta gcggaaacgc tggataacca
    17761 ggaagaagca gaaaagctga ccattgagcc taccgtcaaa aatcagtcat tacctttagc
    17821 agtttcttat gttggtgaaa cagctgaagg tgcgcagaag cagctggcga agtatatcca
    17881 gcaagttgac gaccaggtaa acgaagaact ggaaaaagac ctgaaagaca acatcgcgct
    17941 gcgtatgaaa aacttgcagg attctctgaa aactcaggaa gtagtcgcgc aggagcagaa
    18001 agatctgcgt atccgtcaga ttcaggaagc gttgcagtat gcgaatcagg cgcaggtgac
    18061 aaagccacag gttcagcaga ctgaagatgt gacacaagat acgttgttcc ttttggggag
    18121 cgaagcgctg gagtcgatga ttaagcacga ggcgacccgt ccgttggtgt tctcaccaaa
    18181 ctactatcag acacgtcaaa acctgctgga tatcgaaagc ttaaaagttg atgatcttga
    18241 tattcatgct taccgctatg taatgaaacc gacgttacct attcgtcgcg atagtccgaa
    18301 aaaggcaatc accttgattc tggcggtgct gctgggcggc atggttggcg cggggattgt
    18361 gctggggcgt aatgctctgc gtaattacaa cgcgaaataa tctttgcagc tttaaagaaa
    18421 acgggcaggg tggtgacacc ttgcccgttt ttttttgccg gatgcgacaa caacatcgca
    18481 tccgcttacc ccgcaactca ctgatgccgt ttacgcaggt tctcaatcac cgtcgttaag
    18541 tccagatcct gatcctgcaa cagcaccagc aggtgataca tcaagtcaga tgcctcgttg
    18601 gtcagctcaa agcggtcatg taccgttgct gccagtgcgg tttccacgcc ttcttcgcct
    18661 actttttgcg caatgcgttt ggtg
//
