LOCUS       AB812076               17188 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli genes for O-antigen biosynthetic locus, partial
            sequence, strain: E4378.
ACCESSION   AB812076
VERSION     AB812076.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 17188)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..17188
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="E4378"
                     /db_xref="taxon:562"
                     /note="serogroup:O179"
     gene            <1..899
                     /gene="wcaM"
     CDS             <1..899
                     /gene="wcaM"
                     /codon_start=3
                     /transl_table=11
                     /product="colanic acid biosynthesis protein"
                     /protein_id="BAQ01956.1"
                     /translation="ILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDSDILISDH
                     VIERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGK
                     HFVIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGK
                     YLSIPQNFRVNNIQLDNTHLVYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQH
                     LFMRNINVMQESSLGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNERGQSSVDI
                     DRINHHIVNVEKINFRLPERRE"
     gene            1062..1967
                     /gene="galF"
     CDS             1062..1967
                     /gene="galF"
                     /note="O179_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ01957.1"
                     /translation="MDEIMTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVT
                     IMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNE
                     TGRSQVLAKRMAGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGR
                     YVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQV
                     FVKYGLRNLKEGAKFRKGIEKLLSE"
     gene            2303..3763
                     /gene="wzx"
     CDS             2303..3763
                     /gene="wzx"
                     /note="O179_02"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAQ01958.1"
                     /translation="MNFLVYLALSIVSKLIASVREFGVGFIWGTGSIVDAFILAMMLP
                     MFFIDIASVMFNSTYIGIYVNSANKERRFFFKDVFYFTLIYVLFTNIIVIFFLKEYIA
                     YSDIPIETKHIIDNIIIYIVVYYSLLAFCEFYKAHLMACEKQKMMPLPMICANIVFIS
                     TMYYFSEGANDIALVSCFVFSSVIQFILYIPLIIKKDSVYIMNSSVSHSREANKKLFL
                     KNLVPVFFNAAVNQSSKITDKVIASSLIIGSLSSLYFAQQLYALYVNIIIVSVLSFAY
                     PKICKKANENKYEFSSYIVQVIIVLFVLLVYPVMLGWRYAQDIFKFILVNSTTQNIKV
                     VSEMFMVLLSVVVFESISASLKRAFWALNKMKVTVYISGFTVIINIILSVLLSSYYGP
                     KGLVYSYCAATILSTMLLIFYFNKVSKITIPKNIFLPIMTASIISVTFYILLGFFRID
                     LNKPISLLIPGLIVVLGMFLLFVCFNKNSISKVLKE"
     CDS             3760..4899
                     /note="O179_03"
                     /gene="weuI"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01959.1"
                     /translation="MKNICFVNSYACLGGAERSLQSLIEGFIAKDYNVHVIIGEDRGP
                     LLDWVREKKIRYKIIEQPSLQKKYGRVLFPLYLLHFLILFYLYIKKHKIEIIHANTFR
                     SRIYCALVKYITSCKLICHVRDIEYSRLNKALLSIYDHTIAISDAVKSTVLKGTKGNS
                     LLRKKIITIHNGVKVCHLPQVKKKRDDNNINIGMFARFDEWKCHHILIEAANKLKKNN
                     VEMKVGKKINYYLYGEAIRESEAIYYAHIKKMVHDLQLENDVFFMGFHDEPINEMHKM
                     NIIVCPSDNEPFGRVLIEAMAIKKIVIASNNGGVKDILGSKFSDLTFEPRNAEALARK
                     IEMYAESQNEFEYLYCDLLYKEYRERFSLESLLNNIEQLYLKDIK"
     gene            4899..6002
                     /gene="wzy"
     CDS             4899..6002
                     /gene="wzy"
                     /note="O179_04"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAQ01960.1"
                     /translation="MFTISPVFFENITFQGSRTLADVLFCISLLLIICKHKKVNISLL
                     GIVYIIIVLVIMSVNAALGFSNASTTINNELFDKLTWLILDRNINEFIPFGDYYRNIL
                     IYTRYLLIPFYFWMGLYYSKLVGKERAIVTLYNGLIICLLLNMLYGIYNDDDRLTGFF
                     ENTAALSSLALLCMLLSLFTKSKYKIILSWVIGIIALLMSQTASAFIGLTAVVLILVF
                     NIRRHHKKTVYITSLLSVVIASIGLMPEIMEFIARYMYTGSLINRINTWSTIINYFDS
                     YQVAILGLGSFPLFADNIFIWLISGFGIFSFVIYMYLVSIGNKSQKSALFISLLLWQG
                     VLFPGFIMPYMLMTTFITLGILSNNKGCENECI"
     CDS             5983..6540
                     /note="O179_05"
                     /gene="weuJ"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyltransferase"
                     /protein_id="BAQ01961.1"
                     /translation="MKMSVFSCVIKDVKRYDQKVLYGFVIALTKIGFWAVLNYRLGKL
                     MREQIKIPILKQILWFLTGLTRLVINIITGIDIPYSANIGGGFKICHFGTIFISSKVV
                     IGDNCTIHQGVTIGKGGHNTETDEPVIGNDVFIGANATVIGAITIGSRVRIGSNVCCY
                     KSINDDMTVVANRIRVIKHENSSVT"
     CDS             6518..7642
                     /note="O179_06"
                     /gene="weuK"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01962.1"
                     /translation="MKIVLLHNEIKPFRLPLFNYLNSIYDVKIYCLRSNKLTENNIKD
                     VEYGRYIRIPKMQDLEIPLDLWFFLKNEKPDVIISTDLGYAITYIGYLYSRVNQCKFV
                     LWNEQWSDILHPRRYLTKPLERLICRKADKILSFGYKHAEYLIQLGAKENNISIVPNA
                     VPDFYPLSKSHNENNEFFYIPWIHDVTKIKIVCPGRLVKFKGHETILNSAVGIIKANK
                     NARFIFAGSGPEFGQLQQMVNKLGLNDYVFITGVTFNEEMKNALLINADLVILASVKS
                     KKIRAVEAWGLVVNEAIQYKKKIIVSDATGVANELIIDNETGGVFENGNHIDLQNKIL
                     SCINHPEQWNIYAEKAYEKLITDYSMDVLIKKITFALEEI"
     CDS             7645..8757
                     /note="O179_07"
                     /gene="wfaU"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01963.1"
                     /translation="MKVFLISINSDKENTGGGIYLRTLKTLYERNGYKIHIFSKDCDL
                     YKVKKNILTDLVGRLLLCPSYIGYYIFHILIFSRNFNTIAIHSTRLGIIARVIKLIHP
                     EKCIIVHSDNVESALIRELRSKKSLAKTILMFIDKLLMPLSEKYCGKYSDKMTFITEE
                     DKSQSLKYNLIPTSNKYITLPVLLKKQKLKELEKDNSVLFTGSFDFYPNQHAFMRLIN
                     LANANVNTKFVAAGRYLSKYIERGQIKLPSNMFIFSDISSDDMELLYRKAILFICPVS
                     YGSGMKTKIAEALSYDLYVIADERSTFGYQAAVTNRVLYKQSSDFFDFCEIGQLEKII
                     ENLKNTSNSCSITPYVVFEKYYSIDSGMNIFGRLLQ"
     CDS             8754..9947
                     /note="O179_08"
                     /gene="wbaD"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01964.1"
                     /translation="MKKILVLTPRFPFPVIGGDRLRIYKICQELSKHYELTLLSLCET
                     RKELTMEVDDKVFKNIYRVYLSRLQSKLNVISAIPTRKPLQIAYYSSWKFKSKVNELM
                     PYHDAVFSHLIRTGDYVKNINIKSILEMTDAISLNYKRVAESNSEFSLRKLVYIFERK
                     RLEKYERNIVNSFDMVSLISGIDKDYLYPQGHHKVKVYGNGVDTKNLIYKKRTVNNTE
                     FISIIFIGNMYSLQNMDAVKWFCHEILPNLCDATYKFKLKVVGKIKDSDRDYLNTIPN
                     VEVTGTVDDINEACSDGHLAICPIRLGAGIQNKILEYMALGLPCITSSVGFEGIGATD
                     GREILIANNLEEYQRKIHELINNKELFDKVSSNARTFVETHFSWEARLNPLINDLDFL
                     IGNSI"
     gene            9944..11338
                     /gene="manC"
     CDS             9944..11338
                     /gene="manC"
                     /note="O179_09"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="BAQ01965.1"
                     /translation="MILPVIMAGGTGSRLWPLSRTHFPKQFHKLINEQSLLINTITRL
                     KGFSHLPPLIISNEDHRFLVAEQVRQIRADVSGIILEPVGKNTCPAITLAALHAIQNG
                     DDPYLLILAADHSIGNESEFNISVNNAVKYASADYLVTFGVIPTSPETGYGYIEKGKK
                     IEKNGFFVKSFTEKPDYQTAHSYITSKNYLWNSGMFMFKASVFLQELKTFEPEILDIC
                     GKAIQNSNKDLDFIRIDSELFSKCKSESIDYAIMEKTDKAVVVPMDAQWNDVGSWSAL
                     WDLAEKDNDNNHISGDVVIKNSTGNYIRSESGLVATIGINNLIIVNTKDALLIADRAD
                     AQNIKDIIKKLKTVERRELDYFTNEFRSWGMIEKIDYSTNHVANRITINPGKKISQQI
                     HYHRNEHWIVVSGTALINIDGEDFLLSENESTFIKIGQEHSIMNPGIVPLIIIEIQTG
                     KFISEKDVIRVRNN"
     gene            11335..12777
                     /gene="manB"
     CDS             11335..12777
                     /gene="manB"
                     /note="O179_10"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="BAQ01966.1"
                     /translation="MKVINNYLICNEIITTNRISFGTSGARGLVIDFSHDVCAAFTHA
                     FLSVIDDKYNFNKVALAIDNRPSSYEIAQACAFAIKQHGFNVEYHGVIPTPALAHYSM
                     QKNIPCIMVTGSHIPFDRNGLKFYRPDGEITKEDELAIINSEYTFSPVGVLPHLETST
                     QGADYYLERYVSLFNPEILKGKRIGVYEHSSAGRDLYAPLFNQMGAEVISLGRSDEFV
                     PIDTEAVSDEDRILAREWSKKYNLDAIFSTDGDGDRPLVADENGEWLRGDILGLLTAI
                     ELNIKALAIPVSCNTAIEESNKFASIQRTKIGSPYVIAAFADLAKQFDSVAGFEANGG
                     FLLASDLQINGKELKSLPTRDAVLPALMLLIASRNSTISQLINNLPQRFTWSDRVKNF
                     PSDSSQQIIKNAISSPNNFFNSLGYESLFCSAIDETDGARFTLNNGDIIHLRPSGNAP
                     ELRCYAEASDENQAKQYVTNVLGNIISLIS"
     gene            12974..14380
                     /gene="gnd"
     CDS             12974..14380
                     /gene="gnd"
                     /note="O179_11"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ01967.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKEQRVAASKVLSGPQAQPAGDKGEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            14629..15795
                     /gene="ugd"
     CDS             14629..15795
                     /gene="ugd"
                     /note="O179_12"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ01968.1"
                     /translation="MKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKKQSP
                     IVDKEIEEYLATKDLNFRATTDKYDAYKNADYVIIATPTDYDPKTNYFNTSSVEAVIR
                     DVTEINPNAVMVIKSTIPVGFTKSIKERLGIDNLIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            15885..16919
                     /gene="wzz"
     CDS             15885..16919
                     /gene="wzz"
                     /note="O179_13"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ01969.1"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDLEQIDLIDLLV
                     QLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGS
                     AVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQPLPLAVSYVGETP
                     EGAQKQLAKYIQQVDDQVNEELEKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQ
                     IQEALQYANQAQVTKPQVQQTEDVTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQT
                     RQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLG
                     RNALRNYNSK"
     gene            complement(17016..>17188)
                     /gene="hisI"
     CDS             complement(17016..>17188)
                     /gene="hisI"
                     /codon_start=3
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ01970.1"
                     /translation="QKVGEEGVETALAATVHDRFELTNEASDLMYHLLVLLQDQDLDL
                     TTVIENLRKRHQ"
BASE COUNT     5444 a   2909 c   3515 g   5320 t
ORIGIN
        1 ccatcttacg ccagggattt cataaccaga ttatcggtgc caacatcacc aactgtaagt
       61 tcagcgactt acaaggcgac gccattgaat ggaacgtggc aattaacgac agtgatattt
      121 tgatctccga ccatgtcatc gagcgcatca actgtactaa tggcaaaatc aactggggca
      181 tcggcatagg ccttgcgggg agtacctacg ataataacta cccggaagac caggcagtga
      241 aaaactttgt cgtggcgaat atcacgggat cggattgtcg gcagttgatc catgttgaaa
      301 atggcaaaca ttttgttatt cgtaatatca aagctcgcaa tatcacgccg gatttcagta
      361 agaaagcagg cattgataac gcgacagttg ctatttacgg ttgtgacaat ttcgtgattg
      421 ataatattga aatgattaat agcgccggga tgttaatcgg ctatggggta attaaaggca
      481 aatatctctc gataccgcaa aatttccgag tgaataatat tcaactggat aacacccatc
      541 ttgtttataa attgcgcggc atccaaatct ccgccgggaa tgctgtctcc tttgtggcgc
      601 tgactaacat tgagatgaag cgtgcgtcgc tggagttaca caacaaaccg caacatcttt
      661 ttatgcgtaa tattaatgtg atgcaggaat cctctcttgg acccgcattg agcatgaact
      721 tcgacatgcg caaagacgtt cgcggcgtct ttatggcgaa aaaagaaaca ctcctgtctc
      781 ttgcaaatgt tcatgcggtg aatgaaagag gacaaagctc cgtcgatatc gacaggatta
      841 atcaccatat tgttaatgtg gaaaagatta actttagatt gccagaacgg agagagtaga
      901 tttgcgacca ttcctggaaa aatggagcca tacttaggaa caatgctact gcaatccaca
      961 acgaagcggc gtaacatcac aagtaattca gtaatcaatt cagggtaatt gatgctggcg
     1021 aaaaaaatcg aacaagctat aattcagcaa ccattttaca ggtggatgaa ataatgacga
     1081 atttaaaagc agttattcct gtagcgggtc ttgggatgca tatgttgcct gccactaagg
     1141 cgattcccaa agagatgcta ccgatcgtcg acaagccaat gattcagtac attgttgacg
     1201 agattgtggc tgcagggatc aaagaaatcc tcctggtaac tcacgcgtcc aagaacgcgg
     1261 tcgaaaacca cttcgacacc tcttatgaat tagaatctct ccttgaacag cgcgtgaagc
     1321 gtcagctgct ggcggaagtg cagtccatct gtccgccggg cgtgaccatt atgaacgtgc
     1381 gtcagggcga acctttaggt ttgggccact ccattttatg tgcacgaccc gccattggtg
     1441 acaacccatt tgtcgtggtg ctgccagacg ttgtgatcga tgacgccagc gccgacccgc
     1501 tgcgctacaa ccttgctgcc atgattgcgc gcttcaacga aacgggccgc agccaggtgc
     1561 tggcaaaacg tatggcgggc gatctctctg aatactccgt cattcagacc aaagagccgc
     1621 tggaccgtga aggcaaagtc agccgcattg ttgaatttat cgaaaaaccg gatcagccgc
     1681 agacgctgga ctcagacatc atggccgttg gtcgctatgt gctttcagca gatatttggc
     1741 cggaacttga acgcactcag cctggtgcat ggggacgtat tcagctgact gatgccatcg
     1801 ctgaactggc gaaaaaacag tccgttgatg ccatgctgat gacaggtgac agctacgact
     1861 gcggtaaaaa aatgggttat atgcaggtgt ttgtgaagta tggactacgc aacctcaaag
     1921 aaggggcgaa gttccgtaaa gggattgaga agctgttaag cgaataatga aaatctgacc
     1981 ggatgtaacg gttgataaga aaattataac ggcagtgaag attcgtggcg aaagtaattt
     2041 gttgcgaata ttcctgccgt tgttttatat aaacaatcag gataacaacg agttagcaat
     2101 aggattttag tcaaagtttt ccaggatttt ccttgtttcc agagcggatt ggtaagacaa
     2161 ttagcgtttg aatttatgag ggctttgcgg ggttagttgc aaagttcata gcatcccatt
     2221 gagaaggtac gcagtgtact ggtagctttc aagccagggg cggtagcgtg cttttttatc
     2281 aagttaggtt gtaataccat caatgaactt tcttgtctac ttggctttgt caattgtaag
     2341 taaactaatt gcatctgtac gggaattcgg tgtcggtttc atttggggga cgggaagtat
     2401 tgttgatgca ttcattctgg caatgatgct tccaatgttt tttattgata tcgcaagtgt
     2461 catgtttaac tcgacatata ttggtatata tgttaatagc gccaataaag aacgtagatt
     2521 tttttttaaa gatgttttct attttacttt aatatatgtt ttgtttacaa atataatagt
     2581 gatatttttc ttaaaagaat atatagctta ttccgacata ccaattgaga caaaacatat
     2641 aattgataat attataatat atatcgttgt gtattattct ttattggctt tctgtgagtt
     2701 ttacaaagca cacttgatgg cgtgtgagaa acaaaaaatg atgccattgc cgatgatatg
     2761 cgcaaatatt gtttttatat caacaatgta ctatttttca gagggtgcaa atgatatagc
     2821 attagtatca tgctttgtat tttcttctgt tattcagttt atactatata tacctctaat
     2881 tataaaaaaa gatagtgtgt atataatgaa ttcatctgta agccatagta gagaagctaa
     2941 taaaaaattg tttttaaaaa atttggtgcc agtttttttt aatgctgcag tgaatcagtc
     3001 atctaaaata acagataaag taatagcatc ttcattaatt atcgggagtt tatcatcgct
     3061 atactttgca cagcagttat atgcactata tgtaaatatt attattgtaa gtgtattatc
     3121 ctttgcatat cccaagatat gtaaaaaggc caatgagaat aaatatgaat tcagctctta
     3181 tattgtacag gtgattatag ttttatttgt tttgttagtg tatccagtta tgctggggtg
     3241 gaggtatgca caggatatat tcaagtttat acttgtgaat tctactacgc agaacataaa
     3301 agtagtaagt gaaatgttta tggttctttt aagtgtggtt gtttttgaat caatatcagc
     3361 ttctctaaaa agagcattct gggcattaaa taaaatgaaa gtcacagtgt atataagcgg
     3421 atttactgtt attatcaata ttatcttaag cgtattgctt tcaagttatt atggcccaaa
     3481 agggttggtt tattcatatt gtgctgcaac aatattatca acaatgctat taatatttta
     3541 ttttaataag gttagcaaaa taacaatccc taagaatatt ttcttgccga taatgacagc
     3601 ctctattata tccgttacct tttatatatt attgggtttc tttagaatag acttaaataa
     3661 accaatttct ttattaattc ctggattgat agttgtctta ggaatgtttt tattatttgt
     3721 ttgcttcaat aaaaatagta tcagtaaggt gcttaaagaa tgaagaatat atgtttcgta
     3781 aatagttatg catgtctggg gggagcagaa agaagtttgc agtctcttat tgaaggattt
     3841 atagccaaag attataatgt tcacgttatt ataggtgagg atcgagggcc acttcttgat
     3901 tgggttaggg aaaagaaaat acgatataaa ataattgaac agccttcgct acagaaaaaa
     3961 tatggaaggg tattgttccc attgtactta ttgcactttt taattttgtt ctatctttat
     4021 ataaaaaaac acaaaatcga aataattcat gcaaacacat ttcgttcaag aatatattgt
     4081 gcattggtga aatacattac ttcatgcaaa ttgatctgcc atgtaagaga tattgagtat
     4141 tcaagattaa ataaagcgct gttaagtata tatgatcata caatagcaat atccgatgct
     4201 gttaaaagca cggttttgaa aggaacaaaa ggaaacagtt tattacgaaa aaaaatcatt
     4261 actatacata atggtgttaa ggtatgccat ctccctcaag ttaaaaagaa aagagacgat
     4321 aataatataa acatagggat gtttgcacgg ttcgatgaat ggaagtgtca tcatatactt
     4381 attgaggctg caaacaaact aaaaaaaaat aatgtagaaa tgaaggtagg aaaaaaaata
     4441 aattattatc tctatggaga agcgattcga gagagcgagg ctatttatta tgctcatata
     4501 aaaaaaatgg ttcatgattt acagttagaa aatgatgtgt tctttatggg ttttcatgat
     4561 gaacctataa atgaaatgca caaaatgaat attatagttt gtccttcaga taatgaacca
     4621 tttgggcgtg tattaattga ggcaatggca attaagaaaa ttgtaattgc ttcaaacaac
     4681 ggcggagtta aagatatact aggtagcaaa ttctcagatt taacttttga acctagaaat
     4741 gctgaagctc tagctaggaa aattgaaatg tacgcagaaa gtcaaaatga gtttgagtat
     4801 ttatactgtg atttgcttta taaggagtat agagaaaggt tttcgttaga gtcacttttg
     4861 aataatattg aacagctata tttaaaagat ataaaataat gtttactata tcacctgtat
     4921 tttttgaaaa tattacattt caaggctcta ggactcttgc ggatgttctt ttttgcataa
     4981 gtttattgtt gattatatgt aaacataaaa aggtcaacat aagtctatta ggtatagttt
     5041 atataattat tgtcctagta ataatgtcag tgaatgctgc gttaggattt tctaatgcaa
     5101 gcacaacaat taataacgaa ctctttgata aactcacatg gttaatatta gatagaaata
     5161 taaatgaatt tatccctttt ggtgactatt ataggaatat attgatatat actcgatatt
     5221 tactaattcc attttatttc tggatgggac tgtactattc aaaattggta ggtaaggaaa
     5281 gagcaattgt cactttatat aacgggctga ttatttgtct cttgttaaat atgctgtatg
     5341 gtatatataa tgatgatgat agactaacag gtttttttga aaatactgca gcgctttctt
     5401 cattagcatt attgtgtatg ctactttctc tcttcactaa gtccaaatat aaaataatac
     5461 tatcttgggt tattggcatt atcgcattat taatgtctca aactgcaagt gcttttattg
     5521 gtcttacagc agtagtttta attttagtat ttaacattcg aagacatcat aaaaagactg
     5581 tatatatcac atcactgttg agtgttgtta ttgcatcgat tggcttaatg ccagaaatta
     5641 tggaatttat tgctcgatat atgtatacag gcagtttaat aaatagaata aatacatgga
     5701 gtactattat taattatttc gattcctatc aagttgcgat actaggactt ggttcttttc
     5761 ctttatttgc agataatata tttatctggt taatatctgg ttttgggata ttttcatttg
     5821 taatatatat gtatctagta agtatcggaa ataaaagtca aaaatcagca ttattcatat
     5881 cattattatt atggcaaggg gtcttgtttc caggatttat tatgccttac atgttgatga
     5941 caacatttat aacactggga attttaagta ataataaggg ttgtgaaaat gagtgtattt
     6001 agttgtgtta taaaggatgt taaaagatac gatcaaaagg tactgtatgg atttgttatt
     6061 gcacttacaa aaataggttt ctgggctgtt cttaattaca ggttaggaaa gttaatgaga
     6121 gaacagataa aaatacctat attaaaacaa atattgtggt ttttaaccgg attaacaaga
     6181 ttggtcatta atataataac gggtattgat attccttatt cagctaatat tgggggagga
     6241 tttaaaattt gtcattttgg tacaatcttt atatcctcta aagttgtaat tggcgataat
     6301 tgtacgatac accaaggagt tactatagga aaaggcggtc ataatactga aacggatgaa
     6361 cctgttattg gtaatgatgt ttttattgga gctaatgcaa ctgttattgg agcaataact
     6421 attggttcaa gagttagaat aggaagcaat gtttgctgtt ataaaagcat aaacgatgat
     6481 atgacagttg tagcaaatcg aataagagtt attaagcatg aaaatagttc tgttacataa
     6541 tgagatcaaa cctttccgat tacctttatt taattactta aatagtatat atgatgttaa
     6601 aatctattgc ttacgaagta ataaattaac ggaaaataat ataaaggacg tagaatacgg
     6661 acgttatatt aggataccca aaatgcaaga tcttgaaatt ccacttgatc tttggttttt
     6721 tttgaaaaat gaaaagccag atgttattat ttctactgat cttggttatg caataacata
     6781 tattggatat ttatactcta gagttaatca atgtaaattt gttttatgga acgagcaatg
     6841 gagtgatata ctacatccta ggcgatatct gacaaaacca cttgaaagat taatttgcag
     6901 aaaagccgac aaaatattgt cttttgggta taagcatgcc gaatacctga ttcaattagg
     6961 tgctaaagaa aataatatat ctatagtgcc aaatgcagtc cctgattttt accctttatc
     7021 aaaaagtcat aatgagaata atgaattttt ttatattcca tggattcatg atgtaacaaa
     7081 aataaaaatc gtctgccccg gccgtttagt aaaatttaaa gggcatgaga ctatattaaa
     7141 ttcagcagtt ggtattataa aagcaaataa aaatgctaga tttatttttg caggatcagg
     7201 ccctgaattt ggacagttac aacagatggt aaataaattg gggttgaatg attatgtgtt
     7261 tattacggga gtaacattta atgaggaaat gaaaaatgct cttttaataa acgctgattt
     7321 agtaatttta gcgtctgtaa aatcaaaaaa aataagagca gttgaagcgt ggggattggt
     7381 tgttaatgaa gctattcaat ataagaaaaa gataatagtt agtgatgcta ctggagtggc
     7441 taacgaatta attattgata atgaaactgg aggtgtattt gaaaatggga atcatataga
     7501 tctacaaaat aaaatccttt catgtattaa tcatcctgaa caatggaata tatacgctga
     7561 aaaagcctat gagaaattaa ttactgatta ttcaatggat gttttaataa aaaaaatcac
     7621 gttcgcttta gaggaaattt aatcatgaaa gtgtttctaa tatcaataaa ttcggacaaa
     7681 gaaaacacag gtggtggtat atacctccgt acactgaaaa cgctttacga acggaatggt
     7741 tataaaattc atattttctc gaaagattgt gatttatata aagtaaaaaa aaatatacta
     7801 actgatttag ttgggcgatt gctattatgt ccatcataca taggttatta tatatttcat
     7861 attttaatct ttagcagaaa tttcaataca atagcaattc atagcacaag actagggatt
     7921 atcgcgagag ttatcaaact gattcatcca gagaaatgta taatagtaca ttctgataat
     7981 gttgaatcag cattaattcg agaattacgt tcaaaaaaat cattagcaaa aacgatactg
     8041 atgttcatcg ataaattatt aatgcctctt tctgaaaagt attgtggaaa atattctgac
     8101 aaaatgactt ttataactga agaagataaa agtcaaagtc taaaatacaa tttaattccc
     8161 actagtaata aatatattac tttacctgtt ttgttaaaga aacaaaaatt aaaagaactt
     8221 gaaaaagaca attcagttct atttacgggt agttttgatt tttatccaaa tcagcatgca
     8281 tttatgagat taataaatct agcaaatgct aatgtcaata ctaaatttgt tgctgctggt
     8341 agatatttat ctaagtatat tgagagagga caaataaaat taccatcaaa tatgtttatt
     8401 ttttcagata tctcctcaga tgacatggag ttactttata gaaaagctat attatttata
     8461 tgccctgtaa gttatgggag tggcatgaaa actaaaattg ccgaagcgct tagttatgat
     8521 ctttatgtca tagctgatga aagaagtact tttggctatc aggcggcagt tacaaacagg
     8581 gttctttata agcagtcaag tgattttttt gatttttgcg aaataggtca gcttgaaaaa
     8641 ataattgaaa atttgaaaaa tacatctaat tcgtgctcaa ttacacccta tgtcgttttt
     8701 gaaaaatatt atagtattga ttctggtatg aacatttttg gtagattgct acaatgaaaa
     8761 aaatattagt tttaactcct cgttttccat ttcctgtaat tggcggtgat cgattacgaa
     8821 tttataaaat atgtcaagaa ctatctaaac attatgagtt gactctattg tcattatgtg
     8881 agacaagaaa agagttaact atggaagttg atgataaagt attcaagaat atttatcggg
     8941 tttatttatc acgacttcaa tcaaaattaa atgttatatc tgcaattccg acaagaaaac
     9001 ctttacaaat agcttattat tcatcttgga aattcaaaag taaagttaat gaattaatgc
     9061 catatcatga tgcagtattc tctcatttaa tcagaactgg agattatgtt aaaaatatta
     9121 atataaaatc aatactcgaa atgacagatg caatatctct taattataaa agagttgctg
     9181 agtcaaatag tgagtttagt ttgagaaagt tagtgtatat atttgaacga aagagattgg
     9241 agaaatacga gcgtaatatt gttaatagtt ttgatatggt ttcgttaatt tcaggtatag
     9301 ataaagatta tttataccca caaggccatc ataaagttaa agtttatggt aatggggttg
     9361 acacaaaaaa tttaatctat aaaaaaagga cggtcaacaa tactgagttt atttcgatca
     9421 tttttattgg aaatatgtat tcattacaga atatggatgc tgttaaatgg ttttgtcatg
     9481 aaattttacc aaatttatgc gatgctactt ataagtttaa gctaaaagtt gttggtaaaa
     9541 ttaaagattc agaccgtgat tatttaaaca ctatccctaa tgtcgaagtg actggaactg
     9601 ttgatgatat caatgaagca tgtagcgatg ggcatcttgc aatttgccct atacgtttag
     9661 gtgctggtat ccagaacaaa attctcgaat atatggcact tggtttacca tgtataacat
     9721 catcagtggg gtttgaaggg atcggcgcta ctgacggcag ggagattctt atagcgaata
     9781 acttagaaga atatcaacga aagattcatg agcttattaa taataaagaa ttatttgata
     9841 aagtctcgtc taatgctcgc acttttgttg aaacacattt ttcttgggag gctagactca
     9901 atccattaat taatgactta gatttcttaa taggaaattc aatatgattt taccagtaat
     9961 tatggccggt ggtacggggt ccagactttg gccattatct cggactcatt tccctaaaca
    10021 atttcataaa ttaattaacg aacagtcctt attaattaat acaattacac ggcttaaggg
    10081 attttcccat ttaccaccac tgataatttc gaatgaagat caccggttct tggttgccga
    10141 gcaagtgagg caaatacgtg cggatgttag tggaatcatt ttggagcctg tcggaaaaaa
    10201 cacctgtccg gcaattactc tagcggcgct tcatgctatt caaaatggcg atgatcctta
    10261 tcttttaatt ctcgctgcag atcattcgat cggtaatgaa agtgaattta atatttcagt
    10321 caataatgct gtaaagtatg cttctgcaga ttatctagta acatttggtg ttatcccaac
    10381 aagtcctgaa actggatatg gatatattga gaaaggaaaa aaaattgaaa aaaatggttt
    10441 tttcgttaag agttttacgg aaaagccaga ttatcaaaca gcccattcct acataacatc
    10501 aaaaaattat ttatggaata gcggtatgtt tatgtttaaa gcctctgtat tccttcagga
    10561 attaaaaact ttcgaaccag agatattgga tatttgtggt aaagcaattc aaaactcaaa
    10621 taaagatttg gattttattc gtattgattc tgaacttttt agtaaatgta aatcagaatc
    10681 gattgattat gctattatgg aaaaaactga taaagcagtt gttgttccta tggatgcgca
    10741 atggaatgat gttggttcgt ggtctgcact ttgggactta gctgaaaaag ataacgataa
    10801 taatcatatc agtggtgatg tcgtaattaa aaattccaca ggtaattata tccgctcaga
    10861 atcaggatta gttgcaacta tcggtataaa taacttaatt attgtcaata ctaaagacgc
    10921 attgttgatt gctgatcgtg ctgatgctca aaacataaag gacataatca aaaaactcaa
    10981 aactgttgag cggcgtgagc ttgattattt tacaaatgaa tttcgttcat ggggtatgat
    11041 tgaaaaaatt gattacagta ctaatcatgt agcaaataga ataacgatca atccaggtaa
    11101 gaaaatttct caacagattc attatcatag aaatgagcac tggatagttg tctctggaac
    11161 cgctttaatt aatattgatg gtgaagattt tttattatct gaaaatgagt caacattcat
    11221 caaaattgga caggaacatt cgatcatgaa tcctgggata gttcctttga ttattattga
    11281 aattcaaaca ggaaaattta tatcagagaa ggatgttatt agagtaagga ataattgaaa
    11341 gtgataaaca actatctaat ttgtaatgaa ataattacaa ctaatcgcat ttcgttcgga
    11401 actagtggcg ctcgcggtct tgttattgat ttttcccatg atgtttgtgc tgcgttcact
    11461 catgcgtttc tttctgttat tgatgacaaa tacaatttta ataaagttgc cttagcaatt
    11521 gataaccgcc caagcagtta cgaaatcgct caggcatgcg ccttcgctat caaacaacat
    11581 gggttcaatg tcgaatatca tggtgtaatt ccgactcctg cattagctca ttattcgatg
    11641 cagaaaaaca ttccctgcat aatggtcaca gggagtcata tcccttttga tcgtaatggc
    11701 ttaaaattct acagacctga tggtgaaatc actaaagagg atgagctcgc aattataaat
    11761 agtgagtata cattttcgcc tgtaggtgta ttacctcatc ttgaaacaag cactcaaggt
    11821 gcagactact acctcgagcg ttatgtttct ctttttaatc ccgagatttt aaaggggaaa
    11881 agaatagggg tatatgaaca ttctagtgcg ggacgcgatt tatatgctcc tctttttaat
    11941 caaatgggtg cagaggtcat ttccctcggt aggagtgatg agttcgttcc gattgatacg
    12001 gaagcagtaa gcgatgaaga tcgtatactt gcaagagagt ggtctaaaaa atataatctt
    12061 gatgctattt tctcaacaga tggcgatggt gatcgtcctt tagttgccga tgaaaatggt
    12121 gaatggttaa gaggcgatat tctgggacta cttactgcta ttgaacttaa tatcaaggcg
    12181 ttggctattc cagtgagttg taatacagca attgaagagt ctaataaatt tgcaagtata
    12241 caacgaacga aaataggttc tccttatgta attgcagcat ttgcagatct tgctaagcaa
    12301 tttgattcag tcgctggttt tgaagctaat ggtggttttc tccttgcctc cgatttacaa
    12361 attaatggca aggaattaaa atcgttacct acacgagatg ctgtgttacc agcattaatg
    12421 ctcttaatag cttctcgcaa tagtactatt tctcaactga ttaataatct tcctcagcga
    12481 ttcacttggt cagatagagt taaaaacttc ccttcagatt caagtcaaca aattataaaa
    12541 aatgccatat cgtcacccaa taatttcttt aatagtttag gttatgaatc attattctgt
    12601 tccgctattg atgaaacgga tggtgcaaga tttactttaa ataatggtga tattatacat
    12661 ctccgtcctt ccggtaatgc tccagaactc cgttgttatg ctgaggccag tgatgaaaat
    12721 caggctaagc aatatgttac gaatgtgctg ggaaatatta tctctttgat ttcttgatgt
    12781 tataggttta tctacgctta tatgtgtgcg taggtttgat tacacgtaga tgccggtata
    12841 cagaattgaa gaacggtatt tgttgcatta atgaaattca gcactacaca cattcgtgca
    12901 acttgagata acatctcaat catattcaag tcgcgcatac atcgcggtga acaccccctg
    12961 acaggagtaa acaatgtcaa agcaacagat cggcgtcgtc ggtatggcag tgatggggcg
    13021 caaccttgcg ctcaacatcg aaagccgtgg ttataccgtc tctattttca accgttcccg
    13081 tgaaaagacc gaagaagtga ttgccgaaaa tccaggcaag aaactggttc cttactatac
    13141 ggtgaaagag tttgttgaat ctctggaaac gcctcgtcgc atcctgttaa tggtgaaagc
    13201 aggtgcaggc acggatgctg ctattgattc cctcaagcca tacctcgata aaggtgacat
    13261 catcattgat ggtggtaaca ccttcttcca ggacaccatt cgtcgtaacc gtgagctttc
    13321 tgcagaaggc tttaacttta tcggtaccgg tgtttccggt ggtgaagaag gtgcgctgaa
    13381 aggtccttcc attatgcctg gcggacagaa agaagcctat gaactggttg cgccgatcct
    13441 gaccaaaatc gccgcagtgg ctgaagacgg cgaaccgtgc gttacctata ttggtgccga
    13501 tggcgcaggt cactatgtga agatggttca caacggtatt gaatacggtg atatgcaact
    13561 gattgctgaa gcctattctc tcctgaaagg cggcctgaat ctttctaacg aagaactggc
    13621 tcagaccttt accgagtgga ataacggtga actgagcagc tacctgatcg acatcaccaa
    13681 agacatcttc actaaaaaag atgaagacgg taactacctg gttgatgtga tcctggatga
    13741 agcggctaac aaaggtaccg gtaaatggac cagccagagc gcgctggatc tcggcgaacc
    13801 gctgtcgctg attaccgagt ctgtgtttgc acgttatatc tcttctctga aagagcagcg
    13861 tgttgccgca tctaaagttc tctctggccc gcaagcgcag ccagctggcg acaaaggtga
    13921 gttcatcgag aaagttcgtc gtgcgctgta tctgggtaaa atcgtttctt acgctcaggg
    13981 tttctctcag ctgcgcgcag cgtctgaaga gtacaactgg gatctgaact acggcgaaat
    14041 cgcgaagatt ttccgtgctg gctgcatcat ccgtgcgcag ttcctgcaga aaatcaccga
    14101 tgcttatgcc gaaaatccac agatcgctaa cctgctgctg gctccgtact tcaagcaaat
    14161 tgccgatgac taccagcagg cgctgcgtga tgtcgttgct tatgcagtac agaacggtat
    14221 cccggttccg accttcgctg ctgcggttgc ctattacgat agctaccgtg ccgctgttct
    14281 gcctgcgaac ctgatccagg cacagcgtga ctatttcggt gcgcatactt ataagcgcat
    14341 tgataaagaa ggtgtgttcc ataccgaatg gctggattaa tctgatttaa atcaattaat
    14401 caatgcaagg cccggagaaa ccctccgggc ttttttatta tacaaagcgg caggttatgg
    14461 ccttttttta taatttatgg ttaaaaaagc gatataatac agagccgcac agcaggatcg
    14521 ctgccttgac agttcatcta catcagcgtt aaaaatcccg cagtagatga agctgtggtg
    14581 gtggattaat gaccactcta aatgtttaac cggaagaagt cagagctaat gaaaataaca
    14641 atttcaggaa caggttatgt tggtctttca aatggtattc tgattgcgca aaaccacgaa
    14701 gtggttgcac tggatatcgt ccaggccaaa gtggacatgc ttaacaagaa gcagtcaccg
    14761 attgttgata aggagattga agagtatctg gcgactaaag atctcaattt ccgcgctacg
    14821 acagataagt atgacgcgta taaaaatgcc gattacgtta ttattgccac acctaccgat
    14881 tatgatccga aaacgaatta ttttaatacc tcaagcgtgg aagcggtcat tcgcgatgtg
    14941 acagaaatta atcctaatgc tgtcatggtg attaaatcta caattccggt aggtttcacc
    15001 aaatcaatta aagaacgtct gggtatcgat aaccttattt tctctccgga attcctccgc
    15061 gaaggtaaag ctctttacga taaccttcat ccgtcacgta ttgtaatcgg tgagcgttcg
    15121 gaacgcgcag aacgttttgc tgcgttatta caggaaggcg cgattaagca aaatatcccg
    15181 accctgttca ccgattcaac cgaagcagaa gcgattaaac tgtttgctaa tacctatctg
    15241 gcgatgcgcg tagcatactt taatgaactg gatagctatg cagaaagttt aggtctgaat
    15301 actcgccaga ttatcgaagg cgtttgtctc gacccacgca ttggcaacca ttacaacaat
    15361 ccgtcgtttg gttatggtgg ctattgcctg ccgaaagata ccaagcagtt gctggcgaac
    15421 tatcagtctg tgccgaataa cctgatctcg gcaattgtcg atgctaaccg cacgcgtaaa
    15481 gattttattg ccgatgccat tttgtcacgc aagccgcaag tggtgggtat ttatcgtctg
    15541 attatgaaga gcggttcaga taacttccgc gcgtcttcca ttcaggggat tatgaaacgt
    15601 atcaaagcga aaggcgttga agtaatcatt tacgaaccgg tgatgaaaga agactcattc
    15661 ttcaactctc gcctggaacg tgatctcgcc accttcaaac aacaagccga cgtcattatc
    15721 tccaaccgta tggcagaaga gcttaaggat gtggcagaca aagtctacac ccgcgatctc
    15781 tttggcagtg actaacatcc tgttatcagg gcgattttcg ccctgattct cttatgttcc
    15841 ctttgtaata attcattctt tttatcattt atcctatagc attcatggcg attatcgcta
    15901 aactatggcg acttaaaatt atttcgtccg ttagggtaat gatgagagta gaaaataata
    15961 atgtttctgg gcaaaaccat gacctggaac agattgattt gattgattta ctggtgcagt
    16021 tgtggcgcgg caagatgact atcatcattt ctgtcattgt ggctattgcc ctggctatag
    16081 ggtatctggc cgttgccaaa gaaaagtgga cttccacagc tatcgttact caacctgatg
    16141 tggggcaaat cgctggttat accaacgcga tgaatgtaat ctacggatcg gctgtaccga
    16201 aagtctccga cattcaggct tcacttatcg gacgttacag cactgcattc tcagcattag
    16261 cggaaacgct ggataaccag gaagaagcag agaagctgac cattgagcct accgttaaaa
    16321 accagccgtt accactggcg gtgtcttatg tgggtgaaac acctgaaggt gcgcagaagc
    16381 agctggcgaa gtatatccag caagttgatg accaggtaaa cgaagaactg gaaaaagacc
    16441 tgaaagacaa catcgcgctg cgtatgaaaa acttgcagga ttctctgaaa actcaggaag
    16501 tagtcgcgca ggagcagaaa gatctgcgta tccgtcagat tcaggaagcg ttgcagtatg
    16561 cgaatcaggc gcaggtgaca aagccacagg ttcagcagac tgaagatgtg acacaagata
    16621 cgttgttcct tttggggagc gaagcgctgg agtcgatgat taagcatgaa gcgactcgtc
    16681 cgttggtgtt ctcaccaaac tactatcaga ctcgtcaaaa cctgctggat atcgaaaact
    16741 taaaggttga cgatcttgat attcatgctt accgttatgt gatgaaaccg acgttaccta
    16801 ttcgtcgcga tagcccgaaa aaggcaatta ccttgattct ggcggtgctg ctgggcggca
    16861 tggttggcgc ggggattgtg ttggggcgta atgctctgcg taattacaac tcgaagtaat
    16921 cttttcggtt ttaaagaaaa tgggcagggt ggtgacacct tgcccgtttt ttttgccgga
    16981 tgcgacaaca acattgcatc cgcttaccgc gcaactcact gatgccgttt acgcaggttc
    17041 tcaatcaccg ttgttaaatc cagatcctga tcctgcaaca acaccagcag gtgatacatc
    17101 aaatcagatg cctcgttggt cagctcaaag cggtcatgta ccgttgctgc cagtgcggtt
    17161 tccacgcctt cttcgcccac tttctgcg
//
