LOCUS       AB812078               19016 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli genes for O-antigen biosynthetic locus, partial
            sequence, strain: 92-1250.
ACCESSION   AB812078
VERSION     AB812078.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 19016)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..19016
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="92-1250"
                     /db_xref="taxon:562"
                     /note="serogroup:O181"
     gene            <1..904
                     /gene="wcaM"
     CDS             <1..904
                     /gene="wcaM"
                     /codon_start=2
                     /transl_table=11
                     /product="colanic acid biosynthesis protein"
                     /protein_id="BAQ01990.1"
                     /translation="YAILRQGFHNQLIGANITNCKFSDLQGDAIEWNVAINDRDILIS
                     DHVIERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVEN
                     GKHFVIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIT
                     GKYLSIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKP
                     QHLFMRNIKVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNERGQSSV
                     DIDRINHHIVNVEKINFRLPERRE"
     gene            1079..1972
                     /gene="galF"
     CDS             1079..1972
                     /gene="galF"
                     /note="O181_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ01991.1"
                     /translation="MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNV
                     RQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRS
                     QVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSEIMAVGRYVLS
                     ADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFRKGIEKLLSE"
     CDS             2371..3414
                     /note="O181_02"
                     /gene="weuM"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01992.1"
                     /translation="MKIAFVGYNPGKIGGIEAFSRNMKNDIFPESEFVYEYDEAGTFK
                     VDNCVPLLKRNLFNRVLNRLTNGNYTKSKIKKKLKEKKYDIIILNSPKYLDVSPDLCR
                     TILVQHTTLDNWWKSKYNFGSNRNLAKLVKKVGKVVALSEMEGQVIKNFFRVEANKIR
                     VINFSAGIPFLYGKKEPGKNLIMLARFQNEIKRIDLVIEAMDDLPDYTLNVYGDGKDR
                     DYLIELSKHKKNVKIHSSITDKTSVLDKNNIYVLSSEYEGYPVSVIEAISRKLPVVAR
                     NTFYSASELVKDNGILLDKTWSKDEFCNAVRSCYENYEQYSNNSESYFYKYDITTIKN
                     NWVSLVQELNYAQ"
     CDS             3404..4408
                     /note="O181_03"
                     /gene="wfgC"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01993.1"
                     /translation="MRNDIDVVITWVDGNEPDWIKEYTYYKGCEPGRFRDIGVLKYIF
                     RSLEKNMPWVRKIHFVTNGQYPTWLNLEHPKIYFHAHKDFFIYKDALPVFNSNAIELN
                     FANIPDLSERFILFNDDMLVLKQVKEERFFDNGLPVDYCKLSYPRKGRLYKWLKPQNY
                     LACELINNNYLYLKNTRVNQINKKNLYNKDYNLSTNISNFIFSIFRKVKWFEVYHHPQ
                     PHLKSTWLDKTSELRNAVVRNTIYTKFRAKTDVSHYLYRYQNLLNNKFTPRQYNDHYS
                     IYVKNVNEFNKNIKKYFSNTFLCICEDENMGDTEFIKLRRILIKELEIMFPNKCSYEL
                     "
     gene            4462..5499
                     /gene="fnlA"
     CDS             4462..5499
                     /gene="fnlA"
                     /note="O181_04"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase"
                     /protein_id="BAQ01994.1"
                     /translation="MFKSKVLLITGGTGSFGNAVLKRFLETDIKEIRIFSRDEKKQDD
                     MRKFYRSEKLKFYIGDVRDYQSISNAMRGVDYVYHAAALKQVPSCEFYPLEAVKTNVL
                     GTENVLEAAINHSVKRVVCLSTDKAVYPINAMGISKAMMEKVIVAKGRNLSESNTVIC
                     CTRYGNVMASRGSVIPLFIRQAVNGQPITITDPNMTRFMMTLDDAVDLVLHAFKNGKS
                     GDTFVQKAPAATIDILVKSLLSFLNKEDHPITVIGSRHGEKQFEALCSREEMLVAEDQ
                     GRYYRIPADNRDLNYSKYFEVGEKNLHLIQDYNSNNTEQLDVMGMKNLLRKLDFMREI
                     EAGNIVIPEGV"
     CDS             5502..6380
                     /note="O181_05"
                     /gene="qnlA"
                     /codon_start=1
                     /transl_table=11
                     /product="putative dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAQ01995.1"
                     /translation="MKVLILGASGMLGYSLYANMSEYHEFEVFGTVRDIAGKEHYYNK
                     PKGYIIKNVNILDLDKVKQIVAELKPDVVINCIGLIKQLSISKKYTSAITINALLPHQ
                     LAEICSSYEAKLIHFSTDCVFDGKKGNYKEDDLPTATDLYGKTKHMGEVYYGGHITLR
                     TSIIGHELISSISLVEWFLNQEKEVKGFTKAIFSGLPTAYIAKLLAEKIIPNKSLSGL
                     YHLSTFPINKYDLLTKISKVYDKNINIYKSDEVIIDRSLNSEKLRSEIGFVPPDWDEL
                     IEYMNADFKKWYTLCR"
     CDS             6389..7510
                     /note="O181_06"
                     /gene="qnlB"
                     /codon_start=1
                     /transl_table=11
                     /product="putative UDP-glucose 4-epimerase"
                     /protein_id="BAQ01996.1"
                     /translation="MKVATIVGTRPEIIRLSRIISRLDECTEHTLIHTGQNYDYELNQ
                     IFFNDLNIRAPNIFLECAGDTPAETIANVISKSDQLFEKLKPEALLILGDTNSALSAI
                     SAKRRKIPIFHMEAGNRCFDLRVPEEINRKIVDHIADINLPYSSIAREHLLREGLNPD
                     LVIKTGSPMDEVLNFYASKIDASLSLQKMNVEENKYFLVSVHREENVDSDVNINNFVV
                     LLNTLAKKYSLPIIVSTHPRTRKKIDSLDLKFSPLVQLMKPLGFSDYVKLQQHAKVVL
                     SDSGTITEESSILNFPAINIREAHERPEGFEEASVMFTGMNIDRILQVIAILDQQPKG
                     EKRILRKVYDYEAPNVSEKIVRIIHSYTDYVNRVVWKKY"
     CDS             7510..8712
                     /note="O181_07"
                     /gene="wbwH"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01997.1"
                     /translation="MHLALIIDDYLPDSTRVASKMFHELACAFVNGGHRVTVITPYYG
                     RGNRLKKNHLDGVEVWYFKNPRIKDVGKIKRAFAETVLSLNAWIAIKHEPEIKNFDAV
                     IYYSPSIFFGPLVRKIKEKSKCYAYQILRDMFPQWSVDAGLIRAGSLIEKYFRFFEKI
                     NYSQADYIGLMSQKNVELFNSKYNFCATGVLHNWARFECISYEPKYKKCLGLNDKVIF
                     LYGGNIGHAQDMGNLLRLVRNMLPYDKAHFLFVGQGDEVELVNSLVKQWKLENLTYLP
                     PLTQSEFKVLLSEVDVGLFSLAKNHTAHNFPGKILGYMVNSIPILGSVNDGNDLMPLI
                     NDANAGMVYVNGDDEHLFQAALTLLNDKSIRNNMGKCALALLRKEFDVEGVVIEIINK
                     INGFYEKN"
     CDS             8699..9103
                     /note="O181_08"
                     /gene="wbuC"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAQ01998.1"
                     /translation="MKKIDSEIIDKLFNQAKDSDRKRAHYLLHQSYEEKVQRLLIAFL
                     KNSYVEPHFHKNSNQWEMFIVIQGVFELTKYSEGGSIIERIIIEAGADILAVEIYPCE
                     IHSVRCLSEKGLLMEVKEGPFNPLEAKEYLVN"
     gene            9169..10419
                     /gene="wzy"
     CDS             9169..10419
                     /gene="wzy"
                     /note="O181_09"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAQ01999.1"
                     /translation="MNILDKKKNSTSFNYYKITTGLYIILTMYSLLVSIYLSIPLLLY
                     GIITNKKGTPLFIALFFSILGYSFTPPFEFDLYRHYESYEYYLQYNEFLYPIKDFYLS
                     FLFLIGKNLSLKKEFLYFISILIYYTSILTVVLKLKKNVPLTGTYFFIIFVLFILNNT
                     VVEITGLRFTTALGFISLFIYYNYIESRKKTSYFFLFLSVLSHFSVIILPIVIILLRL
                     LYKLFNSRLNAIIMIFTSVIAGLYFVEPIVAFAVIGVEKLFNIYIGAETYTSGLWGAD
                     RVTLHGFSQTGIMFENIKLGISILIPVIISITFILNKDYGKNELTKLFVACSIIFFIF
                     IPFDTVYLRYQYLLIVTALIIFATKNYKFKYLDGQFIGISMIFLKISMQITVGLLSTY
                     VFYIRGLKFDFINTNLVAVLFNIM"
     gene            10438..11709
                     /gene="wzx"
     CDS             10438..11709
                     /gene="wzx"
                     /note="O181_10"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAQ02000.1"
                     /translation="MNIFKTAILSLISTIIKLLSALIINKVISIFIGPSGIALIGQFQ
                     NLIQMTNTLSQGGILSGVTKYTAEYNKHSPENLENLWGTALRIITFLSIIIGLLLFFF
                     AGTLSSYLFSTQGYSVFIQLLGCVTIFTSVNNYALAILNGLKKIKLYVLVNIYQSIIS
                     LILSILFVILYSLKGAFLALILNQSVVFITLLFVFYKNSKLINIKKIIRHMSNEEVKK
                     LFSFSLMALTSAIVGPVSLMLIRNYIQGNISINASGYWQSMWYISSMYLLVVTTTLSI
                     YYLPRLSELVSNDDLKIELIKGIKIIVPLVVAASLTVYLLRDFIISLLFTSEFLSMRN
                     LFQWQVCGDVLKITAWLFSYVLIAKAQSKIFIILEVINFSLFTALSIFMIHIYGLIGG
                     SYGYFLSNLIYLILVSIAVKIRFFKQHNANI"
     CDS             11721..12848
                     /note="O181_11"
                     /gene="weiN"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ02001.1"
                     /translation="MAKYIFIARNTIPLANPAGLVIYRIAKALSNLKHNVEIFSLNKP
                     SGEQQIPKWLTESDDIHVNGVNLTKKNILFSYLKFLFSLSGTIKKELKKNETIYIVTH
                     TNPLYTHWIGFICKLIFNKRIKWISSFTDPYVRSPFSGYAKFTLGTCVRILEQRLSFF
                     FSDKIVFVTDTMRDFICNGNKKALNKSIVVPFFYLSNWKEKILNYDKIKEKRNEQRLL
                     IMHAGSIYGNRDASKFIDALSDHESTIIFKNFGVVNQKIQYSSANIVITSPLPYDDMM
                     VNLKKADYILIIDSFFKDIKNPYMPSKVVDAMYLHKPIIGITESNSELDFFLRKTGNI
                     SIPNDRKIISSVLSNLKQNSKCDFSMYADLNLSDKFRELEC"
     CDS             12921..13919
                     /note="O181_12"
                     /gene="gne"
                     /codon_start=1
                     /transl_table=11
                     /product="putative UDP-glucose 4-epimerase"
                     /protein_id="BAQ02002.1"
                     /translation="MILVTGGLGYIGSHTVVELLSRGYEVIILDNFSNSHPGVGSKIQ
                     TISGVKPLIFEGDIRDVRLLNKIFSDNKISGVIHFAGLKSVSESIRNPLEYYSNNVAG
                     TLNLIEYVLRYRINNFIFSSSATVYGSPEKIPLDESCDIGRTTNPYGTSKYLVERILQ
                     DISKAHKELNVTILRYFNPVGAHPSGLIGESPVGVPNNLMPFISLVANGKFEYVSVYG
                     NDYDTPDGTGVRDFIHVMDLATGHVAALENQNTENNLHIYNLGAGIGYSVLDIINKFE
                     EVNGVKVNYKFCDRREGDIGECWSDPSLAFEELKWKATKTLDDMVMDAWKWQKNNS"
     gene            14037..15443
                     /gene="gnd"
     CDS             14037..15443
                     /gene="gnd"
                     /note="O181_13"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ02003.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            15691..16857
                     /gene="ugd"
     CDS             15691..16857
                     /gene="ugd"
                     /note="O181_14"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ02004.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDEIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            16947..17981
                     /gene="wzz"
     CDS             16947..17981
                     /gene="wzz"
                     /note="O181_15"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ02005.1"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLV
                     QLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGS
                     AVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQSLPLAVSYVGETP
                     EGAQKQLAKYIQQVDDQVNEELGKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQ
                     IQEALQYANQAQVTKPQIQQTQDVTQDTMFLLGSEALESMIKHEATRPLVFSSNYYQT
                     RQNLLDIDNLDVDKLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLG
                     RNALRNYNAK"
     gene            complement(18078..18689)
                     /gene="hisI"
     CDS             complement(18078..18689)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ02006.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVSIAPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ"
BASE COUNT     5976 a   3246 c   3879 g   5915 t
ORIGIN
        1 ttacgccatc ttacgccagg gatttcataa ccagcttatc ggtgccaaca tcaccaactg
       61 taagttcagc gacttacaag gcgacgccat tgaatggaac gtggcgatta acgaccgtga
      121 tattttgata tctgaccatg tcatcgagcg catcaactgt accaacggca aaatcaactg
      181 gggtatcggc ataggccttg cgggaagtac ctacgataat aactacccgg aagaccaggc
      241 agtgaaaaac tttgtcgtgg cgaatatcac gggatcggat tgtcggcagt tgatccatgt
      301 tgaaaatggt aaacattttg ttattcgtaa tatcaaagcc cgcaatatca cgccggattt
      361 cagtaagaaa gcaggtattg ataacgccac agtcgctatt tacggttgtg acaatttcgt
      421 gattgataat attgaaatga ttaatagcgc cgggatgtta atcgggtatg gagtaattac
      481 aggcaaatat ctctcgatac cgcaaaattt ccgagtgaat aatattcaac tggataacac
      541 ccatcttgct tataaattgc gcggtatcca aatctccgcc gggaatgctg tctcctttgt
      601 ggcgctgact aacattgaga tgaagcgtgc ctcgcttgag ctacacaata aaccgcaaca
      661 cctttttatg cgtaatatca aggtgatgca ggaatcctct gttggaccag cattgagcat
      721 gaacttcgac atgcgcaaag acgttcgcgg cgtctttatg gcgaaaaaag aaacactgct
      781 gtctcttgca aatgttcatg cggtgaatga aagagggcaa agctccgtcg atatcgacag
      841 gataaatcac catattgtta atgtggaaaa gattaacttt agattgccgg aacggaggga
      901 gtagatttgc gaccattcct ggaaaaatgg agccatactt aggaacaatg ctactgcaat
      961 ccacaacgaa gcggcgtaac atcacaagta attcagtaat caattcaggg taattgatgc
     1021 tggcgaaaaa aatcgaacaa gctataattc agcaaccatt ttacaggtgg atgaaataat
     1081 gacgaattta aaagcagtta ttcctgtagc gggtcttggg atgcatatgt tgcctgccac
     1141 taaggcgatt cccaaagaga tgctaccgat cgtcgacaag ccaatgattc agtacattgt
     1201 tgacgagatt gtggctgcag ggatcaaaga aatcctcctg gtaactcatg cgtccaagaa
     1261 cgcggtcgaa aaccacttcg acacctctta tgaattagaa tctctccttg agcagcgcgt
     1321 aaagcgtcaa ctactggcgg aagtacagtc catttgcccg ccgggcgtga ccattatgaa
     1381 cgtgcgtcag ggcgaaccct taggtttagg ccactccatt ttgtgtgcac gacccgccat
     1441 tggtgacaac ccatttgtcg tggtattgcc agacgttgtg atcgacgacg ccagcgccga
     1501 cccgctgcgc tacaaccttg ctgccatgat tgcgcgtttc aatgaaacgg gccgtagcca
     1561 ggtgctggca aaacgtatgc cgggtgacct ctctgaatac tccgttattc agaccaaaga
     1621 accactggat cgtgaaggta aagtcagccg cattgttgaa tttatcgaaa aaccggatca
     1681 gccgcagacg ctggactcag agatcatggc cgttggtcgc tatgtgcttt ctgcagatat
     1741 ttggccggaa cttgaacgca cgcagccagg tgcatggggg cgtattcagc tgactgatgc
     1801 catcgctgaa ctggcgaaaa aacagtccgt tgacgccatg ctgatgactg gagacagcta
     1861 cgactgtggt aaaaaaatgg gctatatgca agcgttcgtg aagtatgggc tgcgcaacct
     1921 gaaagaaggg gcgaagttcc gtaaaggcat tgagaagctg ttaagcgaat aatgaaaatc
     1981 tgaccggatg taacggttga taagaaaatt ataacggcag tgaagattcg tggcgaaagt
     2041 aatttgttgc gaatattcct gccgttgttt tatataaaca atcagaataa caacgagtta
     2101 gcaataggat tttagtcaaa gttttccagg attttccttg tttccagggc ggattggtaa
     2161 gacaattagt gtttgaattt ttcgggttta gcgcgagtgg gtaacgctcg tcacatcgta
     2221 ggcatgcatg cagtgctctg gtagctgtaa agccaggggc ggtagcgtgc tcatttgtta
     2281 taacgactta caacgtattc acagtatagt ttcggctgtg taaacatggt gtgttgatac
     2341 acaaaagtta taagaataaa ggcgtcagga atgaaaatag catttgttgg atataatccc
     2401 gggaaaattg gtggtataga ggctttttca aggaatatga aaaacgacat tttccctgag
     2461 tctgaatttg tgtatgaata tgatgaagct ggtacattta aagttgataa ctgcgtgccc
     2521 ttattaaaac gtaatctttt taatagagta cttaacagat taacaaacgg aaattacaca
     2581 aaaagtaaaa tcaaaaaaaa attaaaagaa aaaaaatatg atattatcat cttgaactca
     2641 ccaaaatact tagatgtgtc accagatttg tgtagaacaa ttttagttca gcatacgaca
     2701 ctagataatt ggtggaaatc aaaatataat ttcgggagta atcgaaatct ggctaaactt
     2761 gttaaaaaag ttggtaaggt agtagccttg tctgaaatgg aaggccaggt gataaaaaat
     2821 ttttttagag ttgaagctaa caaaattagg gtgataaatt tctcggctgg tatccctttt
     2881 ttatatggca agaaagagcc tggtaaaaac cttattatgc tagcaagatt tcaaaatgaa
     2941 attaaaagaa ttgatcttgt gattgaagct atggatgact tacccgacta tacgttaaat
     3001 gtttatggag atggaaaaga tcgtgattat cttatagaat tatcgaaaca taaaaaaaat
     3061 gtaaaaatac actctagtat aacagataaa acatcagtcc tggataaaaa taatatatat
     3121 gttttgagta gtgaatatga ggggtatcca gtaagtgtta tcgaagctat ttcaaggaaa
     3181 ctaccagtag tagcaagaaa tacattttac tcggcgtctg aacttgtgaa ggataatggt
     3241 atcttattgg ataaaacttg gagtaaggac gagttttgta atgcagtccg ttcttgttat
     3301 gaaaattatg agcaatattc aaataattca gagagctatt tttataaata tgatattacc
     3361 acaataaaaa ataattgggt tagtttggtt caggaactta actatgcgca atgatattga
     3421 tgtggtcatc acatgggttg atggaaatga acctgattgg attaaagaat atacttatta
     3481 taagggctgt gagccgggtc gtttccgaga tataggggta ttgaaatata tatttagaag
     3541 tcttgagaaa aatatgccat gggtgcgtaa aatacatttt gttactaatg gtcaatatcc
     3601 gacttggttg aacttagaac atccaaagat ttattttcat gctcacaaag atttttttat
     3661 ttacaaagat gctcttccag tgtttaattc aaatgcaatt gaattaaatt ttgcaaatat
     3721 tccagattta tctgagcgat ttattttatt taatgatgat atgcttgttt taaaacaagt
     3781 taaggaagag cgtttttttg ataatggact gccagtcgat tattgcaaat tatcataccc
     3841 tcgcaaaggt aggttatata aatggctaaa accgcaaaat tacctagcat gtgaattgat
     3901 taataataat tatttatatt taaaaaacac aagagtgaat caaataaata agaaaaacct
     3961 ttataataaa gattataacc taagtacaaa tatatccaat tttatatttt caatatttag
     4021 aaaagttaaa tggtttgaag tgtatcacca tccgcaacca catttaaaat caacttggct
     4081 ggataaaaca tccgaattgc gtaatgctgt agtcagaaat acaatatata cgaaatttcg
     4141 ggcaaaaact gatgtcagtc attatttgta tcgttatcaa aatctgttga ataataaatt
     4201 tacaccaagg caatataacg atcattattc aatatacgta aaaaatgtta atgaatttaa
     4261 taagaatata aaaaaatact tttcaaatac ttttctttgt atttgtgagg atgagaatat
     4321 gggagataca gaatttatta aattaagaag aatattaata aaggaattag agattatgtt
     4381 cccaaacaaa tgttcatatg aactataata cacttacgtt tgaataaaga taaatttgtt
     4441 attatcgaga gtagggttaa tatgtttaaa tcaaaggtgt tgttaataac tggtgggact
     4501 ggttcttttg gtaatgcagt tttgaagcgt tttcttgaaa cggatataaa agaaattcgt
     4561 atattttcta gggacgaaaa aaaacaagat gatatgcgca agttttatcg ttcggaaaaa
     4621 ctaaaatttt atattggtga tgtgagagat taccaaagca tctcaaatgc aatgcgtgga
     4681 gttgattacg tttatcatgc cgctgcgttg aaacaagttc cctcatgtga gttttatccg
     4741 cttgaagcag ttaaaactaa tgtgttaggt actgaaaatg ttttagaagc cgcaattaat
     4801 cattctgtga aacgtgttgt atgtttaagt acagataaag cagtttatcc cataaatgca
     4861 atggggatat ccaaagcaat gatggaaaaa gtgattgtag ctaaaggacg taatcttagt
     4921 gaaagtaaca ctgttatttg ttgcacgcgt tatggcaatg taatggcgtc gcggggatct
     4981 gtaattccat tattcatcag gcaagcagtt aatggtcaac caataaccat aactgatcca
     5041 aatatgacgc gttttatgat gacgcttgat gatgcagttg atctagttct acatgctttc
     5101 aagaatggta agagtgggga tacttttgtg caaaaagctc ctgctgctac gattgatatt
     5161 ttggttaaat cgctactttc ttttttaaat aaagaagatc atcctattac tgtaatcggt
     5221 tctcgccatg gcgagaaaca atttgaagca ctatgcagta gagaggaaat gttagtagcg
     5281 gaggatcaag gtcgctatta tcgcatccct gctgataatc gtgatttaaa ttactcaaaa
     5341 tattttgaag ttggtgagaa aaatcttcac ttgattcaag attataattc aaataacaca
     5401 gaacaacttg atgttatggg aatgaaaaat cttttaagaa agctagactt tatgcgtgaa
     5461 atagaggctg gaaacattgt aattcctgaa ggagtataga tatgaaagtg cttattttag
     5521 gggctagcgg catgttaggg tatagcctct acgcaaacat gagtgaatat catgaatttg
     5581 aagtatttgg aacagtacga gacatcgcag ggaaggaaca ttactacaat aaaccaaaag
     5641 gatacataat aaaaaatgtt aatatcttag atttagataa agtgaaacag atagttgctg
     5701 agttaaaacc tgatgttgtt attaattgca ttggtctaat taaacaactt tctatatcaa
     5761 aaaaatatac gtcagcaata acgattaatg cattattgcc tcatcagttg gctgaaatat
     5821 gttcctctta tgaagcaaaa ctcatccatt tttcaacgga ttgcgtattc gatggcaaaa
     5881 aaggtaacta taaggaggat gatttaccta cagccacaga tctatatggt aaaacaaaac
     5941 atatgggtga ggtttattat ggagggcaca ttacactaag aacatctata attgggcatg
     6001 aattgatatc ttctataagt ttagttgagt ggttcctgaa tcaagaaaaa gaagttaagg
     6061 gtttcactaa agctatattt tcaggactac ctacagcgta tattgcaaag ttgctagctg
     6121 aaaaaatcat ccctaataaa tccttaagtg gattatatca tttatccaca ttcccgatta
     6181 ataagtatga cctattaaca aaaatatcaa aagtatatga taaaaatata aatatttata
     6241 agtctgatga ggtaatcatt gatagaagtt taaattctga aaaattaaga agcgaaattg
     6301 gttttgttcc acctgattgg gatgaactta ttgaatacat gaatgctgat tttaaaaaat
     6361 ggtacacgtt atgcagatga ataaaaaaat gaaagttgct actattgtcg gaactcgtcc
     6421 tgaaatcatc agattatcaa gaataatatc tagactagat gagtgcactg aacatacgct
     6481 tatccatacc ggacaaaact atgattatga attgaaccaa atatttttta atgatttgaa
     6541 tatacgagct cctaatattt ttcttgaatg cgcaggcgat actcccgcag aaacaatcgc
     6601 taatgtaata agcaaatcag atcaattatt tgaaaaattg aaacctgaag cacttcttat
     6661 attaggggat accaatagtg cattatctgc tatatcagcc aaaagaagaa aaattcctat
     6721 ttttcatatg gaagctggaa atagatgttt tgatttaagg gttcctgagg aaatcaacag
     6781 aaaaatagta gaccatattg ctgacatcaa tttgccatat agctcaattg ctagagaaca
     6841 ccttttacgt gaaggtttaa atccagatct tgtaatcaaa acaggaagtc caatggatga
     6901 agtgttgaac ttttatgctt ctaaaattga tgcgtcttta tctttacaaa agatgaatgt
     6961 cgaagaaaat aaatatttcc ttgtaagcgt gcaccgtgag gaaaacgttg attctgacgt
     7021 aaacattaat aattttgttg tattattaaa tactttagcc aagaaatatt cattacctat
     7081 aatagtgtct actcatccta gaacgcgtaa aaaaattgat tctttagatc ttaagttttc
     7141 acctttagtt cagttaatga agcctcttgg atttagtgat tacgttaaac tacaacaaca
     7201 tgccaaagtt gtcttgagtg atagtggaac gattactgaa gaatcatcta ttttgaattt
     7261 tcccgcgatt aatattcgtg aagcccatga aagacccgaa ggatttgaag aggcatctgt
     7321 aatgtttaca ggtatgaata ttgatagaat ccttcaggtt attgctatat tagatcaaca
     7381 accaaaaggt gaaaaacgga tcttacgtaa agtttatgat tatgaggctc ctaatgtttc
     7441 agaaaagata gttcgtataa tccattccta tactgattat gtaaatcgag ttgtgtggaa
     7501 aaaatattaa tgcaccttgc tcttattatc gatgattatt taccggatag cacaagggtt
     7561 gcatcaaaaa tgttccatga actggcttgt gcatttgtta atggtgggca tagagttacg
     7621 gttataacgc catattatgg gagagggaat aggctaaaaa aaaatcattt ggatggggtt
     7681 gaagtttggt actttaaaaa ccctagaatt aaagatgttg gtaaaattaa gcgagcattt
     7741 gcagagaccg ttctttcgtt aaatgcatgg atagctataa agcatgaacc tgagataaaa
     7801 aattttgatg ctgttattta ttattcgcca tcaatttttt ttggtccatt agtcagaaaa
     7861 attaaggaga agtcaaaatg ttatgcatac caaattctta gagatatgtt tcctcaatgg
     7921 agtgtggatg ctggtctaat tagagcaggt tcattaatag aaaagtattt tcgtttcttt
     7981 gagaaaatta attactcgca ggccgattac atcggcctga tgtcccaaaa aaatgttgaa
     8041 ctcttcaata gtaagtataa tttttgcgca acaggggtat tacataactg ggctcggttt
     8101 gaatgtatat cttatgaacc aaaatacaaa aaatgtttgg gattaaacga caaagtaata
     8161 tttttatatg gcggtaatat tggccatgct caagatatgg gaaatttatt gcgactggtc
     8221 aggaacatgc ttccatatga taaagctcat tttttatttg ttggacaggg ggatgaagtt
     8281 gaactggtta attcattagt gaaacaatgg aaattagaaa atctaactta tctacctcca
     8341 ttaactcagt cagagtttaa agtgctactt tctgaagttg atgttggtct gttttccctt
     8401 gctaaaaatc atacggcgca caattttcca gggaaaatat tgggctatat ggttaactca
     8461 ataccaatat taggcagcgt aaacgatggt aatgatttaa tgcctttaat aaatgatgct
     8521 aatgctggca tggtatacgt aaatggggat gatgagcatc tttttcaggc tgcattaaca
     8581 ttattgaacg ataaaagcat aagaaacaat atgggcaaat gtgcattagc tcttcttcgg
     8641 aaggagtttg atgtagaagg cgttgtaatt gaaataataa ataagattaa tgggttttat
     8701 gaaaaaaatt gattctgaaa taatagataa attattcaat caggcaaaag atagtgatag
     8761 aaaaagagca cattatcttc tacatcaatc ctatgaagaa aaagtacagc gtctgttaat
     8821 agcttttctg aaaaatagtt atgttgagcc tcatttccat aaaaacagta atcaatggga
     8881 gatgtttatt gtaatccaag gtgtttttga attaactaaa tattctgaag gaggttctat
     8941 tattgagcga ataattattg aagctggcgc tgatatttta gctgttgaaa tttatccatg
     9001 tgaaatacat agtgtaagat gcctttctga aaaggggtta ctaatggagg ttaaagaagg
     9061 cccatttaat cctttagagg caaaagaata cttggtaaat tgaaaataca aaaaaagatt
     9121 gaatggtgtt gattgttaag ggtgtaatta catatactaa ataattttat gaatatatta
     9181 gacaagaaga aaaatagcac atcgtttaat tattataaga taactactgg attgtatatt
     9241 attttgacaa tgtatagtct gttggtaagt atttatctta gcatcccttt attattatat
     9301 ggtataataa caaacaaaaa aggaactcct ttatttatag cattattttt tagtattctt
     9361 ggttatagtt ttactcctcc atttgaattt gacttgtata gacattatga gtcatacgag
     9421 tattatttgc agtataatga gtttctttat ccaatcaaag atttctatct tagctttctt
     9481 tttttgatcg ggaaaaatct atccttaaaa aaagaatttt tatattttat ttcaatttta
     9541 atttactata caagcatatt aactgttgtt ttaaaattaa agaaaaatgt acctctaact
     9601 ggaacatatt ttttcataat tttcgttctt tttatattaa ataatactgt tgttgaaatc
     9661 acaggactcc gatttactac cgcgctgggg ttcatttctc tgtttatata ctataactat
     9721 attgaatcaa gaaaaaaaac atcatatttc tttctatttc tttctgtatt aagccatttt
     9781 tctgtaatca tacttcctat tgttatcatt ttattgcggt tgttatacaa attgtttaac
     9841 tctcggttaa atgcaataat aatgattttt acttcagtaa ttgctggttt atatttcgtc
     9901 gaaccaattg ttgcattcgc tgttataggt gtggaaaagt tatttaatat ttatattgga
     9961 gctgagacct atacgagtgg attatggggg gcagatcgag taacattaca cgggtttagt
    10021 caaacaggga taatgtttga aaatattaag ttaggaataa gcatacttat tcctgtaatt
    10081 ataagtataa cttttatttt gaacaaagac tatggtaaga atgaattaac taaattgttt
    10141 gtcgcgtgct ctattatttt cttcattttt attcctttcg atacagtata tctgcgttat
    10201 caatatcttt tgatcgtaac tgcattaata atttttgcaa caaaaaacta taaatttaaa
    10261 tatttagatg ggcaatttat tggtatttcc atgattttct taaaaatatc aatgcaaatt
    10321 acagtagggt tgttatccac atatgttttt tatatacgtg gattaaaatt tgattttatc
    10381 aatacaaacc ttgtggctgt tttgtttaat attatgtaaa gttataggga gggggggttg
    10441 aacattttta aaaccgcaat acttagctta atatctacaa taataaaatt attaagtgcg
    10501 ttaatcataa ataaagtcat ttccattttc attgggccat ctggaattgc tttaattggt
    10561 cagtttcaaa atcttatcca aatgacaaat actctttcgc agggaggtat attgtctgga
    10621 gtaacgaaat acaccgctga atataacaag cactcaccag aaaatctcga aaacttatgg
    10681 ggtaccgcac taagaataat aaccttcctt tcaattataa tcggtcttct tttgtttttt
    10741 tttgctggca cattgtcctc ctacttattt agcacacaag gttatagtgt ttttattcaa
    10801 ttgcttggct gtgttacaat attcacatca gtaaataatt atgcgcttgc aattcttaat
    10861 ggattaaaaa aaataaaact ttatgttttg gtgaatatat atcaaagcat tatttcacta
    10921 atcttatcta ttctttttgt tatattatat agtttaaaag gtgccttttt ggcattaata
    10981 ttaaaccaat ctgtcgtatt tatcactctc ctgtttgttt tttacaaaaa tagcaagcta
    11041 ataaatataa aaaaaattat tagacatatg tctaatgaag aagtaaaaaa actattctca
    11101 ttttctttaa tggctttgac ttctgcgatt gttgggcctg tgtcattaat gttgattaga
    11161 aattatattc aaggcaatat cagtattaat gcttctggtt attggcaatc tatgtggtac
    11221 atttcttcaa tgtacttatt agtagtaact actacattat caatatacta tttaccccga
    11281 ttgtctgagt tagtcagtaa cgatgatctc aaaattgaac ttataaaggg tattaagatt
    11341 attgtgcctc ttgttgtagc tgcctcactt acagtctatt tgctaaggga tttcattata
    11401 tcattacttt ttacgtctga gtttttaagc atgaggaatt tattccaatg gcaggtttgt
    11461 ggtgatgtat tgaaaattac agcttggctt ttctcttatg tattaattgc aaaggctcaa
    11521 tctaaaatat ttatcatatt agaagtgata aactttagtc tatttacagc cttgtcaata
    11581 tttatgattc atatttatgg tttgataggt ggttcatatg gttatttttt atccaattta
    11641 atttatctga tacttgtttc tatcgctgtt aaaatccgct tttttaagca acataatgcg
    11701 aatatttaag gaaataaact gtggctaaat atatatttat agcaagaaat acgattccac
    11761 ttgcaaatcc cgctggatta gtgatttatc gtattgcaaa agccctgtct aatttaaagc
    11821 ataatgtcga gattttttcc ttaaataaac catctggaga acaacaaatt cctaaatggt
    11881 tgactgagag tgatgatatt catgtgaatg gtgttaattt aactaaaaaa aatatattat
    11941 ttagttatct taagtttctt ttttcgctta gtggtaccat aaaaaaagaa ctaaagaaaa
    12001 atgaaacaat atatattgta actcatacta atccgctcta tactcattgg attggtttca
    12061 tatgtaagtt aatttttaat aaaagaatca aatggatttc ttcttttact gatccatatg
    12121 ttagatctcc atttagtggg tatgctaaat ttacgttggg gacttgtgtc cgaatccttg
    12181 agcaaaggct ttcatttttt tttagtgata aaattgtttt tgttacagac acaatgaggg
    12241 attttatatg taatggaaac aaaaaggctc ttaataaatc aattgttgtc ccctttttct
    12301 atttaagcaa ttggaaagaa aaaattctga actatgacaa aataaaagaa aaaaggaatg
    12361 aacagcggtt actgattatg catgcaggtt caatttatgg gaatagagat gcttctaaat
    12421 ttatagatgc cttaagtgac catgaatcaa caattatatt caagaatttt ggagtagtta
    12481 atcaaaaaat tcagtattct agtgctaata tagtaattac ttccccttta ccttatgacg
    12541 atatgatggt taatttaaaa aaggctgatt atatacttat tattgattcc ttttttaagg
    12601 atataaaaaa tccatatatg ccgtctaaag ttgtagacgc tatgtatctg cataaaccaa
    12661 ttatcggaat aacagagtca aactctgaat tggatttttt cttacgtaaa acagggaata
    12721 tatcaattcc taacgataga aaaataatat cgtcagtact atcaaatctt aaacaaaata
    12781 gtaagtgcga ctttagcatg tatgctgatt taaatctttc agataaattt agggaactgg
    12841 aatgttgaac accatccttt ttgtttctat gctctaataa gagaaatgtt tctccaaaat
    12901 gacggagagg aggagtacca atgattttag taacaggtgg tttaggttat attggatctc
    12961 ataccgtagt tgaattgcta tctcgtggtt atgaagtgat tattttggat aacttctcta
    13021 attcacaccc tggcgtagga tctaaaatac agactataag tggtgttaag cctctgatat
    13081 ttgaaggcga tattagggat gttaggttac ttaataaaat attctctgat aataaaattt
    13141 ctggcgttat tcattttgct ggcttaaaat cagtatcgga atcaattagg aatcctctgg
    13201 agtattacag caacaatgta gctggaacat taaatttgat tgaatacgtg ttacgctata
    13261 gaattaataa ttttattttt agttcttcgg ctacagtgta tgggagtcca gaaaaaatcc
    13321 cactggacga gagctgtgat attggtagaa caactaaccc atatgggacc tctaaatatc
    13381 ttgttgaacg aattctccag gatatatcta aagcacataa agaactaaat gtcacaatac
    13441 taagatattt taatccagta ggggctcatc cttcaggctt aattggtgag tctcctgtcg
    13501 gtgttcctaa caatttgatg ccgttcattt ccctcgtagc gaatggtaaa tttgaatatg
    13561 tctctgtgta tggaaatgat tatgacacac cggatggaac tggtgtaagg gacttcatcc
    13621 atgtaatgga tcttgctacg gggcatgttg cggcactaga gaaccagaat accgaaaata
    13681 atttgcatat ctataattta ggtgctggta taggatattc tgtgctagat attataaata
    13741 aatttgagga agttaatgga gttaaagtga attacaaatt ttgtgacaga cgagaaggag
    13801 atataggtga atgttggtca gatccaagtt tggcatttga agagctaaaa tggaaggcga
    13861 ctaaaacctt agatgacatg gttatggatg cttggaaatg gcaaaaaaat aattcttgaa
    13921 tattttaatc tatctttgta gcaaagatat tttaataatt atgtgtagca tttaaccaat
    13981 ttaccgtatc aggtaatttg cttattactc gctttaattc ctgacaggag taaacaatgt
    14041 caaagcaaca gatcggcgtc gtcggtatgg cagtgatggg gcgcaacctt gcgctcaaca
    14101 tcgaaagccg tggttatacc gtctctattt tcaaccgttc ccgtgaaaag acggaagaag
    14161 tgattgccga aaatccaggc aagaaactgg ttccttacta tacggtgaaa gagtttgttg
    14221 aatctctgga aacgcctcgt cgcatcctgt taatggtgaa agcaggtgca ggcacggatg
    14281 ctgctattga ttcccttaag ccatacctcg ataaaggtga catcatcatt gatggcggta
    14341 acaccttctt ccaggatact atccgtcgta accgtgagct ttctgccgaa ggctttaact
    14401 tcatcggtac cggtgtttcc ggtggtgaag agggcgcgct gaaaggtcct tccattatgc
    14461 ctggtggcca gaaagaagcc tatgaactgg ttgctccgat cctgaccaaa atcgccgcag
    14521 tagctgaaga cggtgagcca tgcgttacct atattggtgc cgatggcgca ggtcactatg
    14581 tgaagatggt tcataacggt attgaatacg gtgatatgca gctgattgct gaagcctatt
    14641 ctctgcttaa aggtggcctg aacctcacca acgaagaatt ggcgcagacc tttaccgagt
    14701 ggaataacgg tgaactgagc agctacctga tcgacatcac caaagatatc ttcaccaaaa
    14761 aagatgaaga cggtaactat ctggttgatg tgatcctgga tgaagcggct aacaaaggta
    14821 ccggtaaatg gaccagccag agcgcgctgg atctcggcga accgctgtcg ttgattactg
    14881 agtctgtgtt tgcacgttat atctcgtctc tgaaagatca gcgcgtggcc gcatctaaag
    14941 ttctctctgg cccgcaagca cagccagcag gcgacaaggc tgagttcatc gaaaaagttc
    15001 gccgtgcgct gtatctgggc aaaatcgttt cttacgctca gggcttttct cagctgcgtg
    15061 ctgcgtctga agagtacaac tgggatctga actacggcga aatcgcaaag attttccgtg
    15121 ctggctgcat catccgtgcg cagttcctgc agaaaatcac cgatgcatat gccgaaaatc
    15181 cgcagatcgc taacctgctg ctggctccgt acttcaagca aattgccgat gactaccagc
    15241 aggcgctgcg cgatgtcgtc gcttatgcag tacagaacgg tatcccggtt ccgaccttcg
    15301 ccgctgcggt tgcctattac gatagctacc gtgccgctgt tctgcctgcg aacctgatcc
    15361 aggcacagcg tgactatttc ggtgcacata cttataagcg cattgataaa gaaggtgtgt
    15421 tccatactga atggctggat taatcttatt taactaacaa taaattgagg cctggcgtat
    15481 attgcgccgg gctttttttt gccaattatc ttatagacta aatttcactg cttaatatta
    15541 acttaataaa tatcagctat tcttataaag aaaatctgaa ttgtttttcg ttgcgttgac
    15601 catctgacaa cgtagcgtta aaacttttag ctcttatcag gatgctaaaa acatcatgat
    15661 tcacagttaa gttaattctg agagcatgaa atgaaaatca ccatttccgg tactggctat
    15721 gtaggcttgt caaacgggct tctaatcgca caaaatcatg aggttgtggc attagatatt
    15781 ttaccgtcac gcgttgctat gctgaatgat cgaatatctc ctattgttga taaggaaatt
    15841 cagcagtttt tgcaatcaga tgaaatacac tttaatgcta cattagataa aaatgaagcc
    15901 taccgggatg ctgattatgt catcattgcc actccaaccg actatgatcc taaaactaat
    15961 tattttaata catccagtgt agaatcagta attaaagacg tagttgagat aaatccttat
    16021 gcggttatgg tgatcaaatc aacggttccc gttggtttta ccgcagcgat gcataagaaa
    16081 tatcgcactg aaaatattat attctccccc gaatttctcc gtgaaggtaa agccctttac
    16141 gataatcttc atccgtcacg tattgtcatc ggtgagcgtt cagaacgcgc agaacgtttt
    16201 gcggcgttat tacaggaagg cgcgattaag caaaatatcc ctacactgtt taccgactcc
    16261 actgaagcag aagcgattaa actgtttgct aatacctatc tggcgatgcg cgtagcatac
    16321 tttaatgaac tggatagcta tgcagaaagt ttagggctga atactcgcca gattatcgaa
    16381 ggcgtttgtc tcgatccgcg tattggcaac cattacaaca acccgtcgtt tggctatggt
    16441 ggttattgtc tgccgaaaga taccaagcag ttactggcga actaccagtc tgtgccgaat
    16501 aacctgattt cggcaattgt cgatgcaaac cgcacgcgta aagactttat tgccgatgcc
    16561 attttgtcac gcaaaccgca agtggtgggt atttatcgtc tgattatgaa gagcgggtca
    16621 gataacttcc gcgcgtcttc cattcagggg attatgaaac gtattaaggc gaaaggcgtt
    16681 gaagtgatca tctacgaacc agtgatgaaa gaagattcat tcttcaactc tcgcctggaa
    16741 cgtgatctcg ccaccttcaa acaacaagcc gacgtcatta tttccaaccg tatggcagaa
    16801 gagcttaagg atgtggcaga taaggtctac acccgcgatc tttttggcag cgactaacat
    16861 cctgttatca gggcgatttt cgccctgatt ctcttatgtt ccctttgtag taattcattc
    16921 tttttatcat ttatcctata gcattcatgg cgattatcgc taaactatgg cgacttaaaa
    16981 ttatttcgtc cgttagggta atgatgagag tagaaaataa taatgtttct gggcaaaacc
    17041 atgacccgga acagattgat ttgattgatt tactggtgca gttgtggcgc ggcaagatga
    17101 caattatcat ctctgtcatt gtcgctattg ccctggctat agggtatctg gccgttgcca
    17161 aagaaaagtg gacttccaca gctatcgtta ctcaacctga tgtggggcaa atcgctggtt
    17221 atacgaacgc gatgaatgtg atctacggat cggctgtacc gaaagtctcc gacattcagg
    17281 cttcgcttat cggacgttac agcactgcat tctcagcatt agcggaaacg ctggataacc
    17341 aggaagaagc agagaagctg accattgagc ctaccgttaa aaaccagtcg ttaccattgg
    17401 cggtgtctta tgttggtgaa acacctgaag gtgctcagaa gcagctggcg aagtatatcc
    17461 agcaagttga cgaccaggta aatgaagaac tgggaaaaga cctgaaagac aacatcgcgc
    17521 tgcgtatgaa aaacttgcag gattcgctga agacccagga agtggttgcg caggagcaga
    17581 aagatctgcg tatccgtcag attcaggaag cgttgcagta tgcgaatcag gcgcaggtga
    17641 caaagccgca gattcagcag acacaggacg taacccagga tactatgttc cttttgggga
    17701 gcgaagcgct ggagtcgatg attaagcacg aggcgactcg tccgttggtg ttctcatcaa
    17761 actactatca gactcgtcaa aacctgctgg atatcgacaa tcttgacgtt gataaacttg
    17821 atattcatgc ttaccgctat gtaatgaaac cgacgttacc tattcgtcgc gatagcccga
    17881 aaaaggcaat taccttgatt ctggcggtgc tgctgggcgg catggttggc gcggggattg
    17941 tcttggggcg taacgctctg cgtaattaca acgcgaagta atcttttcgg ttttaaagaa
    18001 aaggggcagg gtggtgacac cttgcccgtt tttttttccg gatgctacaa caatatcgca
    18061 tccgcttacc ccgcaactca ctgatgccgt ttacgcaggt tctcaatcac cgtcgttaag
    18121 tccagatcct gatcctgcaa cagcaccagc aggtgataca tcaagtcaga tgcctcgttg
    18181 gtcagctcaa agcggtcatg taccgttgct gccagtgcgg tttccacgcc ttcttcaccc
    18241 actttctgcg caatgcgttt ggtgccgctg gcatacagtt tggcggtata ggaggtttcc
    18301 ggatcggcag atttacgttc ggcgagcagt tgttccagtt gatacaggaa cagccactgg
    18361 tgagcggtgt cgccgaagca gctgctggtg cctttgtgac aggttggccc gatgggattc
    18421 gctagcacca gtaacgtgtc gttgtcgcag tccggcgcaa tgctcaccac attgaggaaa
    18481 ttgcccgacg tttcgccttt ggtccacagt cgctgtttag tgcgcgagaa gaaagtgact
    18541 ttgccgcttt cgatggtttt gtctaaggct tccgggttca tatagcccag cattaacact
    18601 tcgccggata ccgcgtgttg cacaatcacc ggcataagtc cgtcggtttt ttcccagtcc
    18661 agttcgcggc gttgttgttc tgttaacata tcctgatctc cacgccctgt gttgccaggt
    18721 acgcttttaa ttcaccaata ttgattattt gtttgtggaa tacggaagct gccagcgcac
    18781 cgtcaacgtc ggcatcgcgg aaagcttcga ggaagtgttc catggtgccc gcgccaccgg
    18841 aggcaattag cgggacgtgg caaacttcac gcactttttt cagttgttcg aggtcgtaac
    18901 cgttacgcac gccgtcctga ttcatcatgt tgaggacgat ttctccggca ccgcgttttt
    18961 gcacttcctg tacccagtcg agcgtttccc actgagtgac gcgggtgcgg ctttca
//
