LOCUS       AB811602               18945 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli DNA, O-antigen biosynthetic locus, strain:
            F10018-41.
ACCESSION   AB811602
VERSION     AB811602.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 18945)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..18945
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="F10018-41"
                     /db_xref="taxon:562"
                     /note="serogroup:O18ab"
     gene            <1..891
                     /gene="wcaM"
     CDS             <1..891
                     /gene="wcaM"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="BAQ00662.1"
                     /translation="RQGFHNKIIGANITNCKFSDLQGDAIEWNVAINDSDILISDHII
                     ERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGKHF
                     VIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGKYL
                     SIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQHLF
                     MRNINVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNERGQSSVDIDR
                     VNNHIINVEKINFRLPERRE"
     gene            1054..1959
                     /gene="galF"
     CDS             1054..1959
                     /gene="galF"
                     /note="O018ab_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ00663.1"
                     /translation="MDEIMTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVT
                     IMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGR
                     YVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQA
                     FVKYGLRNLKEGAKFRKGIEKLLSE"
     gene            2332..3417
                     /gene="rmlB"
     CDS             2332..3417
                     /gene="rmlB"
                     /note="O018ab_02"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6 dehydratase"
                     /protein_id="BAQ00664.1"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSIVNVDKLTYAGNLESLA
                     DVSDSERYVFEHADICDAAAMARIFALHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSALDSDKKNSFRFHHISTDEVYGDLPHPDEVNNKEELPLFTETTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     QALPIYGKGEQIRDWLYVEDHARALYTVVTEGKAGETYNIGGHNEKKNIDVVLTICDL
                     LDEIVPKEKSYREQITYVADRPGHDRRYAINAEKIGRELGWKPQETFESGIRKTVEWY
                     LANAKWVENVKSGAYQSWIEQNYEGRQ"
     gene            3417..4316
                     /gene="rmlD"
     CDS             3417..4316
                     /gene="rmlD"
                     /note="O018ab_03"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAQ00665.1"
                     /translation="MNILLFGKTGQVGWELQRALAPLGNLIALDVHSTDYCGDFSNPE
                     GVAETVRSIRPDIIVNAAAHTAVDKAESEPEFAQLLNATSVEAIAKAANEVGAWVIHY
                     STDYVFPGTGEIPWQETDATAPLNVYGETKLAGEKALQEHCAKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKEREELAVINDQFGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAS
                     GTTTWYDYAALVFEEAREAGIPLALNKLNAVPTTDYPTPARRPHNSRLDTEKFQQNFA
                     LVLPDWQIGVKRMLNELFTTTAI"
     gene            4374..5252
                     /gene="rmlA"
     CDS             4374..5252
                     /gene="rmlA"
                     /note="O018ab_04"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="BAQ00666.1"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLGDGNQWGLNLQYKVQPSPDGLAQAFIIGEEFIGG
                     DDCVLVLGDNIFYGHDLPKLMDAAVNKESGATVFAYHVNDPERYGVVEFDKNGTAISL
                     EEKPLQPKSNYAVTGLYFYDNDVVEMAKNLKPSARGELEITDINRIYMEQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKEFIDSGQVRVLAEPL
                     KKNAYGQYLLKMVKGY"
     gene            5257..5814
                     /gene="rmlC"
     CDS             5257..5814
                     /gene="rmlC"
                     /note="O018ab_05"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="BAQ00667.1"
                     /translation="MNVIKTEIPDVLIFEPKVFGDERGFFFESFNQKIFEEAVGRKVE
                     FVQDNHSKSRKGVLRGLHYQLEPYAQAKLVRCIEGEVFDIAVDIRKSSPFFGKWVGVT
                     LSAENKRQLWIPEGFAHGFVVISDTAEFVYKTNNYYSQQAERSIIFDDKDLGIAWPLN
                     THYILSEKDLNAPTFKKISSNEYFK"
     gene            5811..7058
                     /gene="wzx"
     CDS             5811..7058
                     /gene="wzx"
                     /note="O018ab_06"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAQ00668.1"
                     /translation="MSLIKNSFWNLCGYVLPAIVTLPALGIMGRKLGPELFGVFTLAL
                     AVVGYASIFDAGLTRAVIREVAIEKDNEENKLKIISSATVVIIYLSLAASLLLFFFSG
                     HIALLLNISETFFHNVSVSLKILAASIPLFLITQIWLSILEGEERFGLLNIYKSITGA
                     ILAISPALFILIKPSLMYAIIGLVLARFLCFILAFIICYDKVLKAKLTIDIPTIKRLF
                     MFGGWITVSNIISPVLSYFDRFIVSNQLGAANVAFYTAPSEIISRLSIIPGAFSRALF
                     PRLANANNSVERYKTKRLITISLLIIITPIFCIGVLFSEKIMVLWMGASFFGEPGLVL
                     SILLIGFIFNGLAQVPFASIQSRGHAKITAFVHLLELFPYLLLLFYLIKAHGVVGASI
                     AWSVRMIVDYIALSLLDGKYINK"
     gene            7158..8303
                     /gene="wzy"
     CDS             7158..8303
                     /gene="wzy"
                     /note="O018ab_07"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAQ00669.1"
                     /translation="MFSLLGTKSRITSPLPLHFLPWLLTLIVGISNYDQFYEFNEKSF
                     YSLLIWFTVIFIFYFIGELVNYKRENINVYYGLSHIKYECKKYWIIVIPISLYTIFEI
                     YMVGMGGADGFFLNLRLANTLEGYTGKKFILMPAVYPLMMAMFAIVCLTKTSKLNKYS
                     IYFWMLLYCIGTMGKFSILTPILTYLIIYDFKYRLKVKKTIKFTLLIIILALTLHFTR
                     MAENDHSTFLSILGLYIYSPIIALGQLNEVNSSHFGVYTFRFIYAITNKIGLIKELPV
                     NTILDYSYVPVPTNVYTVLQPFYQDFGYTGIIFGAVLYGLVYVSLYTAGVRGNNTQAL
                     LIYALFSVSSATAFFAETLVTNLAGNVKLVLCTILLWRFTVICKPVQ"
     CDS             8312..9220
                     /note="O018ab_08"
                     /gene="wbuG"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ00670.1"
                     /translation="MATYNGEAFIKNQILSLQQQTFSNWRLFIQDDGSTDNTISIIKN
                     FQKSDSRIRLVDDNLKGQGAGKNFLSLIKYSETDYTIYCDQDDIWLENKIFELVKYAN
                     EIKLNVSDAPSLVYADGYAYMDGEGTIDFSGISNNHADQLKDFLFFNGGYQGCSIMFN
                     RAMTKFLLNYRGFVYLHDDITTLAAYALGKVYFLPKYLMLYRQHTNAVTGIKTFRNGL
                     TSKFKSPVNYLLSRKHYQVKKSFFECNSSILSETNKKVFLDFISFCESNNKFTDFFKL
                     WRGGFRLNNSRTKLLLKFLIRRKFSE"
     CDS             9217..10005
                     /note="O018ab_09"
                     /gene="wclU"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ00671.1"
                     /translation="MISILTPTFNRQHTLSRLFNSLILQTDKDFEWIIIDDGSIDATA
                     VLVEDFRKKCDFDLIYCYQENNGKPMALNAGVKACRGDYIFIVDSDDVLTPDAIKLIK
                     ESIHDCLSERKSFSGVGFRRAYIKGGIVGNDLNNFSENIYYLNATEVSNLINGDVAYC
                     FKKESLVKNPFPRIEGEKFVPELYIWNKITDKAKIRFNISKVIYLCEYLDDGLTKNFH
                     NQLKKYPKGFKIYYKDQRKREKTYIKKIKMLIRYLQCCYYEKIK"
     CDS             10002..11108
                     /note="O018ab_10"
                     /gene="wbdM"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ00672.1"
                     /translation="MKILFVITGLGLGGAEKQVCLLADKLSLSGHHVKIISLGHMSNN
                     KVFPSENNVNVINVNMSKNISGVIKGCVRIRDVIANFKPDIVHSHMFHANIITRLSVI
                     GIKNRPGIISTAHNKNEGGYFRMLTYRITDCLSDCCTNVSKEAVDEFLRIKAFNPAKA
                     ITMYNGIDTNKFKFDLLARREIREGINIKNDDILLLAAGRLTLAKDYPNLLNAMTLLP
                     EHFKLIIIGDGELRDEINMLIKKLQLSNRVSLLGVKKNIAPYFSACDIFVLSSRWEGF
                     GLVVAEAMSCERIVVGTDSGGVREVIGDDDFLVPISDSTQLASKIEKLSLSQIRDHIG
                     FRNRERILKNFSIDTIIMQWQELYGTIICSKHER"
     CDS             11419..12546
                     /note="O018ab_11"
                     /gene="wdaW"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ00673.1"
                     /translation="MVRLVNYYMTARTTKVLHLQLLPLLSGVQRVTLNEISALYTDYD
                     YTLVCSKKGPLTKALLEYDVDCHCIPELTREITVKNDFKALFKLYKFIKKEKFDIVHT
                     HSSKTGILGRVAAKLARVGKVIHTVHGFSFPAASSKKSYYLYFFMEWIAKFFTDKLIV
                     LNVDDEYIAINKLKFKRDKVFLIPNGVDTDKFSPLENKIYSSTLNLVMVGRLSKQKDP
                     ETLLLAVEKLLNENVNVKLTLVGDGELKEQLESRFKRQDGRIIFHGWSDNIVNILKVN
                     DLFILPSLWEGMPLAILEALSCGLPCIVTNIPGNNSLIEDGYNGCLFEIRDCQLLSQK
                     IMSYVGKPELIAQQSANARSFILKNYGLFKRNNKVRQLYDN"
     gene            12690..14096
                     /gene="gnd"
     CDS             12690..14096
                     /gene="gnd"
                     /note="O018ab_12"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ00674.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYSVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            14346..15503
                     /gene="ugd"
     CDS             14346..15503
                     /gene="ugd"
                     /note="O018ab_13"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ00675.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDKIHFNATLDKNEAYRYADYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELSEPPRVSWRVFYL"
     CDS             complement(15506..16396)
                     /note="O018ab_14"
                     /codon_start=1
                     /transl_table=11
                     /gene="IS1"
                     /product="transposase of IS629"
                     /protein_id="BAQ00676.1"
                     /translation="MMPLLDKLREQYGVGPLCSELHIAPSTYYHCQQQRHHPDKRSAR
                     AQRDDWLKKEIQRVYDENHKVYGVRKVWRQLLREGIRVARCTVARLMAVMGLAGVLRG
                     KKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWRGFVYVAFIIDVFAGYI
                     VGWRVSSSMETTFVLDALEQALWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLAST
                     GSTGDSYDNAMAESINGLYKAEVIHRKSWKNRAEVELATLTWVDWYNNRRLLERLGHT
                     PPAEAEKAYYASIGNDDLAA"
     CDS             complement(16393..16719)
                     /note="O018ab_15"
                     /codon_start=1
                     /transl_table=11
                     /gene="IS2"
                     /product="transposase of IS629"
                     /protein_id="BAQ00677.1"
                     /translation="MTKNTRFSPEVRQRAVRMVLESQSEYDSQWATICSIAPKIGCTP
                     ETLRVWVRQHERDTGGGDGGLTTAERQRLKELERENRELRRSNDILRQASAYFAKAEF
                     DRLWKK"
     gene            16935..17948
                     /gene="wzz"
     CDS             16935..17948
                     /gene="wzz"
                     /note="O018ab_16"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ00678.1"
                     /translation="MRTWKFPSVRVMMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKM
                     TIIISVIVAIALAIGYLAVAKEKWTSTAIITQPDVGQIAGYNNAMNVIYGQAAPKVSD
                     LQGTLIGRFSSAFSALAETLDNQEEPEKLTIEPSVKNQQLPLTVSYVGQTAEGAQMKL
                     AQYIQQVDDKVNQELEKDLKDNIALGRKNLQDSLRTQEVVAQEQKDLRIRQIQEALQY
                     ANQAQVTKPQIQQTQDVTQDTMFLLGSEALESMIKHEATRPLVFSSNYYQTRQNLLDI
                     DNLDVDKLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALRNY
                     NAK"
     gene            complement(18045..18656)
                     /gene="hisI"
     CDS             complement(18045..18656)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ00679.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVNIAPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ"
BASE COUNT     5517 a   3628 c   4169 g   5631 t
ORIGIN
        1 cgccagggat ttcataacaa gattatcggt gccaacatca ccaactgtaa gttcagcgac
       61 ttacagggcg acgccattga atggaacgtg gcaattaacg acagtgatat tttgatctcc
      121 gaccatatca tcgagcgcat caactgtacc aacggcaaaa tcaactgggg catcggcata
      181 ggccttgcgg gaagcactta cgataataat tacccagaag atcaggcagt gaaaaacttt
      241 gtcgtggcga atatcacggg atcggattgt cggcagttga tccatgttga aaatggtaaa
      301 cattttgtta ttcgtaatat caaagcccgc aatatcacgc cggatttcag taagaaagca
      361 ggtattgata acgccacagt cgctatttac ggttgtgaca atttcgtgat tgataatatt
      421 gaaatgatta atagcgccgg gatgttaatc ggttatgggg taattaaagg caaatatctc
      481 tcgataccgc aaaatttccg agtgaataat attcaactgg ataataccca ccttgcttac
      541 aaattgcgcg gtatccaaat ctccgccggg aatgctgtct cctttgtggc gctgactaac
      601 attgagatga agcgtgcctc gctggagctt cacaataaac cgcaacatct ttttatgcga
      661 aatatcaatg tgatgcagga atcctcagtt ggacccgcat tgagcatgaa cttcgacatg
      721 cgcaaagacg ttcgcggcgt ctttatggcg aaaaaagaaa cactgctgtc tcttgcaaat
      781 gttcatgcgg tgaatgaaag agggcaaagc tccgtcgata tcgacagagt taataaccat
      841 attattaatg tggaaaagat taactttaga ttgccggaac ggagagagta gatttgcgac
      901 cattcctgga aaaatggagc catacttagg aacaatgcta ctgcaatcca caacgaagcg
      961 gcgtaacatc acaagtaatt cagtaatcaa ttcagggtaa ttgatgctgg cgaaaaaaat
     1021 cgaacaagct ataattcagc aaccatttta caggtggatg aaataatgac gaatttaaaa
     1081 gcagttattc ctgtagcggg tcttgggatg catatgttgc ctgccactaa ggcgattccc
     1141 aaagagatgc taccgatcgt cgacaagcca atgattcagt acattgttga cgagattgtg
     1201 gctgcaggga tcaaagaaat cctcctggta actcacgcgt ccaagaacgc ggtcgaaaac
     1261 cacttcgaca cctcttatga attagaatct ctccttgaac agcgcgtgaa gcgtcagctg
     1321 ctggcggaag tgcagtccat ctgtccgccg ggcgtgacca ttatgaacgt gcgtcagggc
     1381 gaacctttag gtttgggtca ctccatttta tgtgcacgac ccgccattgg tgacaatcca
     1441 tttgtggtgg tgctgccgga cgttgtgatc gacgacgcca gcgccgaccc gctgcgctac
     1501 aaccttgctg ccatgattgc acgattcaac gaaacgggtc gtagccaggt gctggcaaaa
     1561 cgtatgccgg gtgacctctc tgaatactcg gtcatccaga ccaaagaacc actggaccgt
     1621 gaaggtaaag tcagccgcat tgttgaattt atcgaaaaac cggatcagcc gcagacgttg
     1681 gactcagaca tcatggccgt aggtcgctat gtgctttctg ccgatatttg gccggaactt
     1741 gaacgcacgc agccaggtgc gtgggggcgt attcagctga ctgatgccat tgccgaactg
     1801 gcgaaaaaac agtctgttga cgcaatgctg atgacaggcg acagctacga ctgcggtaaa
     1861 aaaatgggct atatgcaggc atttgtgaag tatggactac gcaacctgaa agaaggggcg
     1921 aagttccgta aaggcattga gaagctgtta agcgaataat gaaaatctga ccggatgtaa
     1981 cgattgataa gaaaattata acggcggtga agattcgtgg cgaaagtaat ttgttgcgaa
     2041 ttttcctgcc gttgttttat ataaacaatc aggataacaa cgagttagca ataggatttt
     2101 agtcaaagtt ttccagggtt ttccttgttt ccagagcgga ttggtaagat aattagcgtt
     2161 tgaatttttc gggtttagcg cgagtgggta acgctcgtca catcgtaggc atgcatgcag
     2221 tgctctggta gctgtaaagc caggggcggt agcgtgcatt aatacctcta ttaaccaaac
     2281 tgagagccgc ttatttcaca gcatgctctg aaggaatatg gaataaatta agtgaaaata
     2341 cttgttactg gtggcgcagg atttattggt tctgctgtag ttcgtcacat tataaataat
     2401 acgcaggata gtattgttaa tgtcgataaa ttaacgtacg ccggaaacct ggaatcactt
     2461 gctgatgttt ctgattctga acgctatgtt tttgaacatg cggatatttg cgatgctgct
     2521 gcaatggcgc ggatttttgc tctgcatcag ccggatgcag tgatgcacct ggctgctgaa
     2581 agccatgtgg atcgttcaat tacaggccct gcggcattta ttgaaaccaa tattgttggt
     2641 acttatgtcc ttttggaagc cgctcgtaat tactggtctg ctcttgatag cgacaagaaa
     2701 aatagtttcc gttttcatca tatttctact gacgaagtct atggcgatct gcctcatcct
     2761 gacgaagtaa ataataaaga agaattaccc ctctttactg agacgacagc ttacgcgcca
     2821 agcagtcctt attccgcatc aaaagcatcc agcgatcatt tagtccgtgc ttggaaacgt
     2881 acctatggtt taccgactat tgtgactaac tgttcgaata actacggtcc gtatcatttc
     2941 ccggaaaaac ttattccatt ggttattctg aatgctctgg aaggtcaagc gttacctatt
     3001 tatggcaaag gggagcaaat tcgcgactgg ttgtatgttg aagatcatgc gcgtgcgtta
     3061 tataccgtcg taaccgaagg taaagcgggt gaaacttata acattggtgg acacaacgaa
     3121 aagaaaaaca tcgatgtagt gctcactatt tgtgatttgt tggatgagat tgtcccgaaa
     3181 gagaaatctt accgcgagca aattacttat gttgccgatc gtccgggaca cgatcgccgt
     3241 tatgcgatta atgctgagaa gattggtcgc gaattgggtt ggaaaccaca ggaaacgttt
     3301 gagagcggga ttcgtaaaac agtggaatgg taccttgcta atgcaaaatg ggtcgaaaat
     3361 gtgaaaagtg gtgcctatca atcgtggatt gaacagaact atgagggccg ccagtaatga
     3421 atattctcct tttcggcaaa acagggcagg taggttggga actacagcgt gctctggcac
     3481 ctctgggtaa tttgattgct cttgatgttc actccactga ttattgtggt gattttagta
     3541 atcctgaagg tgtagctgaa accgtaagaa gcattcggcc tgatattatt gtcaacgcag
     3601 ccgctcacac cgcagtagac aaagcagaat cagaaccgga gtttgcacaa ttacttaacg
     3661 cgacaagtgt cgaagcgatt gcgaaagcag ccaatgaagt cggcgcctgg gttattcact
     3721 actctactga ctacgtattt ccggggaccg gtgaaatacc atggcaggag acggatgcaa
     3781 ccgcaccgct aaatgtttac ggtgaaacca agttagctgg agaaaaagca ttacaagagc
     3841 attgtgcgaa gcaccttatt ttccgtacca gctgggtata tgcaggtaaa ggaaacaatt
     3901 ttgccaagac aatgttacgt ctggcaaaag agcgcgaaga attagctgtc attaacgatc
     3961 agtttggtgc accaacaggt gctgagttgc tggctgattg tacggcacat gccattcgtg
     4021 ttgcactgaa taaaccagaa gtcgcaggct tataccatct ggtagccagt ggtaccacaa
     4081 cctggtacga ttatgctgcg ctggtttttg aagaggcgcg cgaagcaggc attccccttg
     4141 cactcaacaa gctcaacgca gtaccaacaa cagactatcc tacaccagct cgtcgtccgc
     4201 ataactctcg ccttgataca gaaaaatttc agcagaactt tgcgcttgtc ttgcctgact
     4261 ggcagattgg cgtgaaacgc atgctcaacg aattatttac aactacagct atttaatagt
     4321 ttttgcatct tgttcgtgat ggtggagcaa gatgaattaa aaggaatgat gaaatgaaaa
     4381 cgcgtaaagg tattatttta gcgggcggtt ctggtactcg tctttatcct gtaactatgg
     4441 ctgtcagtaa acagctatta ccgatttatg ataaaccgat gatctattat ccgctctcta
     4501 cactaatgtt agcgggtatt cgcgatattc tgattatcag tacgccacag gatactcctc
     4561 gttttcaaca actgctgggt gacgggaacc agtggggcct gaatcttcag tacaaagtgc
     4621 aaccgagtcc ggatggtctt gcgcaggcat ttatcatcgg tgaagagttt atcggtggtg
     4681 atgattgtgt tttggtactt ggtgataata tcttctacgg tcacgacctg cctaagttaa
     4741 tggatgccgc tgttaacaaa gaaagtggtg caacggtatt tgcctatcac gttaatgatc
     4801 ctgaacgcta cggtgtcgtt gagtttgata aaaacggtac ggcgatcagc ctggaagaaa
     4861 aaccgctaca accaaaaagt aattatgcgg taaccgggct ttatttctat gataacgacg
     4921 ttgtcgaaat ggcgaaaaat cttaagcctt ctgcccgcgg tgaactggaa attaccgata
     4981 ttaaccgtat ttatatggaa caggggcgtt tatccgttgc catgatggga cgtggttatg
     5041 catggctgga cacggggaca catcaaagtc ttattgaagc aagcaacttc attgcaacaa
     5101 ttgaagagcg tcaggggctg aaagtttcct gcccggaaga aattgcttac cgtaaagagt
     5161 ttattgattc tggacaggtt agggtattag ccgagccact taagaaaaat gcttatggtc
     5221 aatatctgct gaaaatggtt aaaggttatt aataaaatga atgtaattaa aactgaaatt
     5281 ccagacgtac tgatttttga accgaaagta tttggtgatg aacgtggatt cttttttgaa
     5341 agttttaacc aaaagatttt tgaggaagcg gtaggtcgca aagttgagtt tgttcaggat
     5401 aaccattcta aatcgagaaa aggagtattg cggggattgc attatcaatt agagccgtat
     5461 gcgcaagcaa aacttgtgcg ttgcattgag ggtgaagtat ttgatattgc tgtagatata
     5521 cggaagtcat ctccattttt tggtaaatgg gttggtgtaa cattatccgc tgaaaataaa
     5581 cgtcaattat ggatccctga agggtttgct catggttttg tggtgattag tgatactgcg
     5641 gaatttgtct ataaaacgaa caattattac agtcaacaag cagagcgaag cataattttt
     5701 gatgataaag acttagggat tgcttggcca ttgaatactc attatattct ttcagaaaaa
     5761 gatttaaatg cgccaacatt taagaaaata tcgagtaatg agtattttaa atgagtttaa
     5821 tcaaaaacag tttttggaac ctttgcgggt atgtacttcc agctattgtg acactaccag
     5881 ctttgggtat tatggggcga aaattaggcc cagaattatt tggtgtattc actttggcat
     5941 tagctgttgt gggttatgca agcatttttg atgcaggcct tactcgcgca gtgatacgag
     6001 aagtcgcaat tgaaaaagat aatgaagaaa ataagttgaa aattatttct tcagcgacag
     6061 ttgtaattat ttatttgagt ttggccgcct cactcttatt attttttttt agtggtcata
     6121 tcgcattgct actgaatatt agtgagactt tttttcataa tgtaagtgtc tcgcttaaaa
     6181 ttctcgcagc atccatacca ttatttttga ttactcaaat atggttgtca attttagaag
     6241 gtgaagaaag atttggctta cttaatatct acaaatcaat taccggagcg atattagcaa
     6301 tctcaccggc attatttata cttattaaac cctctttgat gtatgcgata ataggcttag
     6361 ttctagcaag gtttttatgt tttattttgg cttttataat ttgttacgat aaagtgctta
     6421 aagctaaact aacaatcgat ataccaacaa ttaaaagatt gtttatgttc ggtggttgga
     6481 ttacagtaag taatatcatc agccctgtgc tatcatattt tgataggttt attgtttcaa
     6541 atcaacttgg ggctgctaat gttgcttttt atactgcacc atcagaaatt atttctcggc
     6601 ttagtataat tccaggtgca ttttcaagag ccttattccc aagattagct aatgcaaata
     6661 attccgttga aagatataaa acgaaaagat taattacaat ttcactttta ataatcatca
     6721 cccctatttt ttgtattggc gtgttatttt cagagaagat aatggtttta tggatggggg
     6781 catcattttt tggtgagcca ggtttggtat tatcaatatt actgattggc tttattttta
     6841 atggattagc acaagtacca tttgccagta ttcaatcccg aggtcatgct aagataactg
     6901 cattcgttca tctcttagag ttgtttcctt atttattact tttattttac ctcataaaag
     6961 cacatggggt tgttggcgcg agtattgcgt ggtcagtgag gatgatagta gattatatag
     7021 cattaagtct tttggacggt aagtatatta ataaataaaa ttcaaaatgc aagttaataa
     7081 ctcatggctt tatttgggta ggtgacaatt tataatgata tatattaact ttaactcttc
     7141 ttctagttat agccataatg ttttctcttc tcggcacaaa aagtaggatc acatctccat
     7201 tacctttgca ttttttacca tggttactaa ctttaattgt cgggataagt aattacgatc
     7261 aattttacga gtttaatgaa aaaagctttt actctttgtt gatttggttt acagttattt
     7321 ttatatttta tttcataggg gaactggtta attataaacg tgaaaatata aatgtttatt
     7381 atggtctttc acatattaaa tatgaatgta aaaaatattg gatcattgtc atcccaattt
     7441 cattatatac cattttcgaa atatatatgg ttggtatggg gggagcagat ggattctttc
     7501 tcaatttacg tcttgcaaat acattggagg gctatacggg taaaaaattt atcttaatgc
     7561 ctgctgtata tcctctaatg atggctatgt tcgcaattgt ttgtctaaca aaaacttcca
     7621 aattaaataa atactccatt tatttctgga tgcttttgta ttgtattggc acaatgggaa
     7681 aattttcaat attaacgcca atattgacat atttaattat ttatgacttc aaatacagat
     7741 taaaagtaaa aaaaacaata aagtttacat tgttgataat tatattagct ttgactttgc
     7801 attttacacg tatggctgag aatgaccact caacattttt atctatttta gggctctata
     7861 tttattcacc aataattgct ttaggccagt tgaatgaagt aaatagtagt cattttggtg
     7921 tgtatacgtt tagattcata tatgctataa ctaataaaat tggccttatt aaagaattgc
     7981 cagtaaatac tattcttgac tattcatacg ttcctgtacc aacaaatgta tatactgtac
     8041 ttcaaccatt ttaccaggat tttggttata ctggcatcat atttggagca gtattatacg
     8101 gactagtata tgtgagttta tacacggccg gtgttcgtgg aaataataca caggcattac
     8161 tgatttacgc attgttttca gttagcagtg caacggcttt cttcgctgaa acgctagtaa
     8221 cgaatttagc tggaaatgtg aagttagtat tatgtaccat cttactatgg cgatttacag
     8281 taatatgcaa accagtacag taaccattct aatggccacc tacaatggcg aggccttcat
     8341 caaaaatcag attttgtcac tacaacaaca aacattttct aactggcggt tatttattca
     8401 ggatgatggg tctacagaca atactatatc tataataaaa aacttccaaa aatctgactc
     8461 cagaattcgg ctagttgatg ataatttgaa aggtcaaggt gcaggaaaaa attttttatc
     8521 gctgataaag tacagcgaga cagattatac aatttattgt gaccaagatg atatttggtt
     8581 agaaaacaaa atatttgaat tagtgaagta tgcaaatgaa attaaattga atgtatcaga
     8641 tgcgccttcg ctagtttatg ctgatggcta tgcttatatg gatggtgagg gtacaatcga
     8701 tttttctggg atatctaaca atcatgctga tcaattaaag gattttcttt tttttaatgg
     8761 tggataccaa ggatgttcta ttatgttcaa tcgtgcaatg accaaatttc ttctgaatta
     8821 tcgaggattt gtatatctac atgacgatat cacaacatta gctgcatacg ctcttggtaa
     8881 agtttatttt ctcccgaaat accttatgtt atatagacag cacacgaatg cggtaactgg
     8941 tatcaaaaca ttccgcaatg gattgacttc taaatttaaa tcaccagtaa actatctttt
     9001 atcacgaaaa cattatcagg taaaaaaatc tttttttgaa tgtaacagct ctatcttatc
     9061 agagacgaat aaaaaagttt ttttggattt tatttcattt tgtgaatcaa ataataaatt
     9121 tacagatttt tttaagttat ggcgaggtgg gtttagatta aataacagta gaactaaatt
     9181 attattaaaa ttcttaatac ggagaaaatt tagcgaatga tttcaatact tacacctact
     9241 tttaatcggc aacatactct atcaaggcta ttcaattctc ttatattaca aactgataaa
     9301 gattttgagt ggataataat tgatgatggt agtatagatg caacagcggt acttgtagaa
     9361 gattttagaa aaaaatgtga ttttgacttg atttattgct atcaggaaaa taatggtaag
     9421 cccatggctt taaacgctgg tgttaaagct tgtagaggcg attatatctt tattgttgac
     9481 agtgatgatg tactaactcc cgatgccata aaattaatta aagaatcaat acatgattgc
     9541 ttatctgaga ggaaaagttt cagcggagtc ggttttagaa gagcatatat aaaagggggg
     9601 attgttggta atgatttaaa taatttttca gaaaacatat actatttaaa tgcgactgag
     9661 gttagcaatt taataaatgg tgatgttgca tattgtttta aaaaagaaag tttggtaaaa
     9721 aatccattcc cccgtataga aggtgaaaaa tttgttccag aattatatat ttggaataaa
     9781 ataactgaca aggcgaagat tcgatttaac ataagcaaag ttatatatct ttgtgagtat
     9841 cttgatgatg gtcttactaa aaatttccat aaccagctaa aaaaataccc aaaggggttt
     9901 aagatttatt acaaagatca aagaaaacga gagaaaactt atataaaaaa aataaagatg
     9961 ctaattagat atttgcaatg ttgttattat gagaaaataa aatgaaaata ctatttgtta
    10021 ttacaggttt aggccttgga ggtgctgaga agcaggtttg tcttttagct gataaattaa
    10081 gtttaagcgg gcaccatgta aagattattt cacttggaca tatgtctaat aataaagtct
    10141 ttcctagcga aaataatgtt aatgtcatta atgtaaatat gtcaaaaaac atttctggag
    10201 ttataaaagg ttgtgtcaga attagagatg ttatagctaa tttcaaacca gacattgtac
    10261 acagtcatat gtttcatgca aacattatca ctagattgtc tgtaattggc atcaaaaaca
    10321 gacctggtat tatatcaact gcacataata aaaatgaagg tgggtatttc agaatgctca
    10381 catatagaat aaccgattgt ttaagtgatt gttgtacaaa tgttagcaaa gaagcagtgg
    10441 atgagttttt acggataaaa gcctttaatc ccgctaaagc aattactatg tataatggga
    10501 tagataccaa taaatttaaa tttgatttat tggcaaggag ggaaattcga gaaggtatta
    10561 atataaaaaa tgatgatata ttattacttg ctgcaggtcg tttaacgtta gctaaagatt
    10621 atcctaattt attgaatgca atgactctgc ttcctgaaca ctttaaactt attattattg
    10681 gtgatggtga attgcgtgac gaaattaata tgctaataaa aaaattgcaa ttatctaata
    10741 gggtgtcctt gttgggagtt aaaaaaaata ttgctcccta tttttctgca tgtgatattt
    10801 ttgttctctc ttctcgttgg gaaggatttg gattagtcgt ggcagaagct atgtcatgtg
    10861 agcgaattgt tgttggcacg gattcggggg gagtaagaga agttattggt gacgatgatt
    10921 ttcttgtacc catatctgat tcaacacaac ttgcaagcaa aattgaaaaa ttgtctttga
    10981 gccagatacg tgatcacatt ggttttcgga atcgtgagcg tattttaaaa aatttctcaa
    11041 tagatactat tattatgcag tggcaagaac tctatggaac tataatttgc tcaaaacatg
    11101 aaaggtagat ttatatttgg aacgtgtctt ttgtttgaat ttaattcaat ctcaattgag
    11161 atttttgtat ttcaaaaata ccatcatagc taacgatgat tggtatttgt tttaagatgc
    11221 tttctataaa tatattgacg tttttaatgc gccgaaacga ttgggctggg aacagagaag
    11281 taaaactgtt ttgagaatga agagtttttg agatgtttat ggatattaaa aattgatcca
    11341 gtgaattaat tatttataat aaatcaagat ttaatgttaa taaatgataa ttttttctga
    11401 cactcatatt aattatgagt ggtacggttg gtaaactatt atatgacagc tagaacaact
    11461 aaagttttgc acttacaatt actcccactc ttaagtggcg ttcaaagggt aacattaaac
    11521 gaaattagtg cgttatatac tgattatgat tatacactag tttgctcaaa aaaaggtcca
    11581 ctaacaaaag cattgctgga atatgatgtc gattgtcatt gtatccccga acttacgaga
    11641 gaaattaccg taaagaatga ttttaaagca ttgttcaagc tttataagtt cataaaaaaa
    11701 gaaaaatttg acattgtgca tacacattct tcaaaaacag gtattttggg gcgagttgct
    11761 gccaaattag cacgtgttgg aaaggtgatc cacactgtac atggtttttc ttttccagcc
    11821 gcatctagta aaaaaagtta ttacctttat tttttcatgg aatggatagc aaagttcttt
    11881 acggataagt taatcgtctt gaatgtagat gatgaatata tagcaataaa caaattaaaa
    11941 ttcaagcggg ataaagtttt tttaattcct aatggagtag acactgataa gttttctcct
    12001 ttagaaaata aaatttatag tagcaccttg aatctagtaa tggttggtag attatccaag
    12061 caaaaagatc ctgagacatt attgcttgct gttgaaaaac tgctgaatga aaatgttaat
    12121 gttaagctga cacttgtagg agatggtgaa ctaaaagaac agttagaaag caggttcaaa
    12181 cggcaagatg gacgtataat ttttcatgga tggtcagata acattgttaa tattttaaaa
    12241 gttaatgatc tttttatatt accttctctt tgggagggta tgccattagc aattttagaa
    12301 gcattgagct gtggactacc atgtatagtc actaatattc caggtaataa tagcttaata
    12361 gaagatggct ataatggttg tttgtttgaa attagagatt gtcagttatt atctcaaaaa
    12421 atcatgtcat atgttggtaa gccagaactg attgcacagc aatccgccaa tgcacgatca
    12481 tttattctga aaaattatgg gttatttaaa agaaataata aggtcagaca gctatatgac
    12541 aattaagtga aaccgaaaat ttacagaaga acaggtcatt caaagtaata aataaaatta
    12601 cagttttttt attgcaatga ttcacgtaac atctgcatta catttaagcc gcgcaacccc
    12661 gcggtgacca cccctgacag gagtaaacaa tgtcaaagca acagatcggc gtcgtcggta
    12721 tggcagtgat ggggcgcaac cttgcgctca acatcgaaag ccgtggttat tccgtctcta
    12781 ttttcaaccg ttcccgtgag aagacggaag aggtgattgc cgaaaatcca ggcaagaaac
    12841 tggttcctta ctatacggtg aaagagtttg ttgaatctct ggaaacgcct cgtcgcatcc
    12901 tgttaatggt gaaagcaggt gcaggcacgg atgctgctat tgattccctc aagccgtacc
    12961 tcgataaagg tgatatcatc attgatggtg gtaatacctt cttccaggac accattcgcc
    13021 gtaaccgtga gctttctgcc gaaggcttta acttcatcgg taccggtgtt tccggcggag
    13081 aagagggggc gctgaaaggg ccgtccatca tgcctggtgg ccagaaagaa gcctatgaac
    13141 tggttgcgcc gatcctgacc aaaatcgccg ccgttgctga agatggcgaa ccgtgcgtta
    13201 cctatatcgg tgctgatggc gcaggccatt atgtgaagat ggttcacaac ggtattgaat
    13261 acggtgatat gcaactgatt gctgaagcct attctctcct gaaaggcggt ctgaatctct
    13321 ctaacgaaga actggcacag acctttaccg agtggaataa cggtgaactg agcagctacc
    13381 tgattgacat caccaaagac atcttcacta aaaaagatga agacggtaac tacctggttg
    13441 atgtgatcct ggatgaagca gcaaacaaag gtaccggtaa atggactagc cagagcgcac
    13501 tggatctcgg cgaaccgctg tcgctgatta ccgagtctgt gtttgcacgt tatatctctt
    13561 ctctgaaaga tcagcgtgtt gccgcgtcta aagttctctc tggtccgcaa gcgcagccag
    13621 caggcgacaa agctgaattc attgaaaaag ttcgccgtgc gctgtatctg ggcaaaatcg
    13681 tttcttacgc tcagggcttc tctcagctgc gtgcggcgtc tgaagagtac aactgggatc
    13741 tgaactacgg cgaaatcgcg aagattttcc gtgctggctg catcatccgt gcgcagttcc
    13801 tgcagaaaat caccgatgca tatgccgaaa atccgcagat cgctaacctg ctgctggctc
    13861 cgtacttcaa gcaaattgcc gatgactacc agcaggcgct gcgtgatgtc gttgcttatg
    13921 cagtacagaa cggtatcccg gttccgacct tcgccgctgc ggttgcctat tacgatagct
    13981 atcgtgccgc tgttctgcct gcgaacctga tccaggcaca gcgtgactat ttcggtgcac
    14041 atacttataa gcgcattgat aaagaaggtg tgttccatac tgaatggctg gattaatctg
    14101 atttaaccaa cagtaaaatt gaggcccggc gtatattgca ccgggctttt tttttgccat
    14161 ttatcttata gactaaattt cactgcttaa tattaactta ataaatatca gttattctta
    14221 taaagaaaat ctgaattgtt tttcgtagcg ttgaccatct aataacgtag cgttaaaaca
    14281 tttagctctt atcaggatgc taaaaacatc atgattcaca gttaagttaa ttctgagagc
    14341 atgaaatgaa aatcaccatt tccggtactg gctatgtagg cttgtcaaac gggcttctaa
    14401 tcgcacaaaa tcatgaggtt gtggcattag atattttacc gtcacgcgtt gctatgctga
    14461 atgatcggat atctcctatt gtggataagg aaattcagca gtttttgcaa tcagataaaa
    14521 tacactttaa tgccacatta gataaaaatg aagcctaccg gtatgctgat tatgtcatca
    14581 tcgccactcc aaccgactat gatcctaaaa ctaattattt caatacatct agtgtagaat
    14641 cagtaattaa agacgtagtt gagataaatc cttatgcggt tatggtgatc aaatcaacgg
    14701 ttcccgttgg ttttaccgca gcgatgcata agaaatatcg tactgaaaat attattttct
    14761 ctccggaatt tctccgtgaa ggtaaagctc tttacgataa tctccatcct tcacgtattg
    14821 tcatcggtga gcgttcagaa cgtgcagaac gttttgctgc gttgttacag gaaggcgcga
    14881 ttaagcaaaa tatcccgacc ctgttcaccg attcaaccga agcagaagcg attaaactgt
    14941 ttgctaatac ctatctggcg atgcgcgtag catactttaa tgaactggat agctatgcag
    15001 aaagtttagg tctgaatact cgccagatta tcgaaggcgt ttgtctcgat ccgcgaattg
    15061 gcaaccatta caacaatccg tcgtttggtt atggtggtta ttgtctgccg aaagatacca
    15121 agcagttact ggcgaactac cagtctgtgc cgaataacct gatttcggca attgtcgatg
    15181 caaaccgcac gcgtaaagat tttattgccg atgccatttt gtcacgcaag ccgcaagtgg
    15241 tgggtattta tcgtctgatt atgaagagcg gttcagataa cttccgcgcg tcttccattc
    15301 aggggattat gaagcgtatc aaggcgaaag gcgttgaagt gatcatatac gagccagtga
    15361 tgaaagaaga ctcattcttc aactctcgcc tggaacgaga tctcgccacc ttcaaacaac
    15421 aagccgacgt cattatttcc aaccgtatgg cagaagagct tagtgaaccg ccccgggttt
    15481 cctggagagt gttttatctg tgaactcagg ctgccagatc atcgtttccg atggaagcat
    15541 aataagcttt ttctgcttct gccggaggag tatggcccag cctttccagc aatcgtcgat
    15601 tgttatacca gtccacccac gtgagtgtgg ccagttccac ttctgcacgg tttttccagc
    15661 tcttacggtg tattacctcc gctttgtaaa gaccattgat gctctccgcc atcgcgttgt
    15721 catacgagtc gcctgtactt cctgttgatg ccagtaatcc ggcttcctta agccgctgtg
    15781 tgtaggccag cgatacatac tgagaacctt tatcactgtg atggaccgtg ccggacggtc
    15841 gacgggccca taacgcctgc tccagtgcat ccagcacgaa tgtcgtttcc atggacgatg
    15901 agacccgcca ccccacgatg tatccggcaa acacatcaat gatgaacgcc acatagacga
    15961 agccccgcca tgtgctgacg taagtaaaat cagccaccca cagctggtca ggtcgttctg
    16021 ccacgaactg acggtttacg cggtcgcctg cggcaacggc tttccggctg atggtcgtac
    16081 ggaccttttt accccggaga acaccggcaa gtcccataac cgccatgaga cgtgccacag
    16141 tgcatctggc cactctgata ccttcccgta acaactgacg ccagacttta cgcacaccgt
    16201 ataccttgtg attttcatcg tatacgcgct gtatctcttt cttcagccag tcatcgcgct
    16261 gcgcacgggc actgcgttta tccggatgat gtcgctgttg ctgacagtgg taatacgttg
    16321 acggggcaat atgcagttcg ctgcatagcg gtccgacccc gtactgctca cgcagcttat
    16381 ccagcagtgg catcattttt tccagaggcg gtcgaactcc gccttcgcaa aataagcgga
    16441 agcctggcga aggatatcgt tactgcggcg cagttcacga ttttcacgtt ccagctcttt
    16501 cagacgctga cgttcagcgg tggtgagccc tccatcaccg cccccggtat cccgctcatg
    16561 ctggcgaacc cagacacgca gagtctccgg cgtacagcca atctttggag caatggaaca
    16621 aattgtcgcc cattgtgagt catattcgct ctgactttcc agaaccatac ggactgcccg
    16681 ttgacggact tcgggggaaa aacgagtatt tttagtcatc ctgtttacct ctttctcagg
    16741 aagtttagtc tccaggattc ccggggcggt tcatagggat gtggcagata aggtctacac
    16801 ccgcgatctc tttggcagcg actaacatct tgttatcagg gctatttacg ccctgattgt
    16861 cttttgttac ttacgcaaca attcattatt tttatcactt atcctatagc attcacgggg
    16921 attatcgcta aactatgcgg acttggaaat ttccgtcagt tagggtaatg atgagagtag
    16981 aaaataataa tgtttctggg caaaaccatg acccggaaca gattgatttg attgatttac
    17041 tagtgcagtt gtggcgtggc aagatgacaa ttatcatttc cgtcattgtg gctattgccc
    17101 tggctattgg ttatttggca gtagcgaagg agaaatggac gtcaacagca attatcactc
    17161 agcccgacgt ggggcaaatt gctggctata acaatgccat gaatgttatc tatggtcagg
    17221 ctgcaccgaa agtatcggat ttgcagggga cgttaattgg tcgcttcagt tctgccttct
    17281 ctgcattagc agaaacgctg gataatcagg aagagccaga gaaacttacc atcgaacctt
    17341 ctgttaagaa ccagcaatta ccattgactg tttcttatgt tgggcaaact gcagagggag
    17401 cacaaatgaa gttggcccaa tacattcagc aagttgatga taaagtgaat caagagctag
    17461 aaaaggatct caaagacaac attgctttgg gacggaaaaa cttgcaggac tctttaagaa
    17521 cgcaggaagt agtcgcgcag gagcagaaag atctgcgtat ccgtcagatt caggaagcgt
    17581 tgcagtatgc gaatcaggcg caggtgacaa agccacagat tcagcagaca caggacgtaa
    17641 cccaggatac tatgttcctt ttggggagcg aagcgctgga gtcgatgatt aagcacgagg
    17701 cgactcgtcc gttggtgttc tcatcaaact actatcagac tcgtcaaaac ctgctggata
    17761 tcgacaatct tgacgttgat aaacttgata ttcatgctta ccgctatgta atgaaaccga
    17821 cgttgcctat tcgtcgcgat agcccgaaaa aggcaattac cttgattctg gcggtgctgc
    17881 tgggcgggat ggttggcgcg gggattgtct tggggcgtaa cgctctgcgt aattacaacg
    17941 cgaagtaatc ttttcggttt taaagaaaat gggcagggtg gtgacacctt gcccgttttt
    18001 ttttccggat gctacaacaa tatcgcatcc gcttaccccg caactcactg atgccgttta
    18061 cgcaggttct caatcaccgt cgttaagtcc agatcctgat cctgcaacag caccagcagg
    18121 tgatacatca aatcagatgc ctcgttggtc agctcaaagc ggtcatgtac agtcgcggcc
    18181 agtgcggttt ccacgccttc ttcgcccact ttctgcgcaa tgcgtttggt gccgctggca
    18241 tacagtttgg cagtgtaaga ggtttccggg tcggcagatt tgcgttcggc gagcagttgt
    18301 tccagttgat acaggaacag ccactggtga gcggtgtcgc cgaagcagct gctggtgcct
    18361 ttatggcagg ttggtccgat aggattcgcc agtaccagta gcgtgtcgtt gtcgcagtcc
    18421 ggcgcaatat ttactacgtt gaggaaattg cccgacgttt cgcctttggt ccacagtcgc
    18481 tgtttagtgc gcgagaagaa ggtgactttg ccgctttcga tggttttgtc taaggcttcc
    18541 gggttcatat agcccagcat taacacttcg ccggataccg cgtgttgcac aatcaccggc
    18601 atcagtccgt cggttttttc ccagtccagt tcgcggcgtt gttgttctgt taacatatcc
    18661 tgatctccac gccctgtgtt gccaggtacg cttttaattc accaatattg attatttgtt
    18721 tgtggaatac ggaagctgcc agcgcaccgt caacgtcggc atcgcggaaa gcttcgagga
    18781 agtgttccat ggtgcccgcg ccaccggagg caattagcgg gacgtggcaa acttcacgca
    18841 cttttttcag ttgttcgagg tcgtaaccgt tacgcacgcc gtcctgattc atcatgttga
    18901 ggacgatttc tccggcaccg cgtttttgca cttcctgtac ccagt
//
