LOCUS       AB811612               21470 bp    DNA     linear   BCT 13-DEC-2014
DEFINITION  Escherichia coli DNA, O-antigen biosynthetic locus, strain: H304.
ACCESSION   AB811612
VERSION     AB811612.1  GI:733166222
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. (2014) In press
   PUBMED   25428893
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 21470)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..21470
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="H304"
                     /db_xref="taxon:562"
                     /note="serogroup:O34"
     gene            <1..893
                     /gene="wcaM"
     CDS             <1..893
                     /gene="wcaM"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="BAQ00803.1"
                     /db_xref="GI:733166223"
                     /translation="RQGFHNQIIDANITNCKFSDLQGDAIEWNVAINDSDILISDHII
                     ERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGKHF
                     VIRNIKARNITSDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGKYL
                     SIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQHLF
                     MRNIRVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNEKGQSSVDIDR
                     INHHIVNVEKINFRLPERRE"
     gene            1056..1961
                     /gene="galF"
     CDS             1056..1961
                     /gene="galF"
                     /note="O034_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ00804.1"
                     /db_xref="GI:733166224"
                     /translation="MDEIMTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVT
                     IMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGR
                     YVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQA
                     FVKYGLRNLKEGAKFRKGIEKLLSE"
     gene            2333..3418
                     /gene="rmlB"
     CDS             2333..3418
                     /gene="rmlB"
                     /note="O034_02"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6 dehydratase"
                     /protein_id="BAQ00805.1"
                     /db_xref="GI:733166225"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLA
                     DVSDSERYIFEHADICDAAAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSALDSDKKNSFRFHHISTDEVYGDLPHPDEVNNNEELPLFTETTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KALPIYGKGDQIRDWLYVEDHARALYTVVTEGKAGETYNIGGHNEKKNIDVVLTICDL
                     LDEIVPKEKSYREQITYVADRPGHDRRYAIDAEKISRELGWKPQETFESGIRKTVEWY
                     LSNTKWVDNVKSGAYQSWIEQNYEGRQ"
     gene            3418..4317
                     /gene="rmlD"
     CDS             3418..4317
                     /gene="rmlD"
                     /note="O034_03"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAQ00806.1"
                     /db_xref="GI:733166226"
                     /translation="MNILLFGKTGQVGWELQRALAPLGNLIALDVHSTDYCGDFSNPE
                     GVAETVRSIRPDIIVNAAAHTAVDKAESEPEFAQLLNATSVEAIAKAANEVGAWVIHY
                     STDYVFPGTGEIPWQEADATAPLNVYGETKLAGEKALQEHCAKHLIFRTSWVYASKGN
                     NFAKTMLRLAKEREELAVINDQFGAPTGAELLADCTAHAIRMALNKPEVAGLYHLVAS
                     GTTTWHDYAALVFEEARKAGIPLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFA
                     LVLPDWQVGVKRMLNELFTTTAI"
     gene            4375..5253
                     /gene="rmlA"
     CDS             4375..5253
                     /gene="rmlA"
                     /note="O034_04"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="BAQ00807.1"
                     /db_xref="GI:733166227"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLSDGSQWGLNLQYKVQPTPDGLAQAFIIGEEFIGG
                     DDCALVLGDNIFYGHDLPKLMDAAVNKENGATVFAYHVNDPERYGVVEFNKNGTAISL
                     EEKPLQPKSNYAVTGLYFYDNDVVEMAKNLKPSARGELEITDINRIYMEQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDSGQVRVLAEPL
                     KKNAYGQYLLKMVKGY"
     gene            5258..5803
                     /gene="rmlC"
     CDS             5258..5803
                     /gene="rmlC"
                     /note="O034_05"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="BAQ00808.1"
                     /db_xref="GI:733166228"
                     /translation="MNVIKTEIPDVLIFEPKVFGDERGFFMESFNQKVFEEAVGRKVE
                     FVQDNHSKSCKGVLRGLHYQLEPYAQGKLVRCVVGEVFDVAVDIRKSSPTFGKWVGVN
                     LSAENKRQLWIPEGFAHGFLVLSEVAEFVYKTNNFYSPECERTIKWDDNDLNIKWPLQ
                     LIDNVIVSDKDNKGNALMVSD"
     gene            5805..7061
                     /gene="wzx"
     CDS             5805..7061
                     /gene="wzx"
                     /note="O034_06"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAQ00809.1"
                     /db_xref="GI:733166229"
                     /translation="MKFINLDKRLTSNIISLCLVQGAGYIIPLLTLPYLVKTLGPVSY
                     GVLGFSIAFTQYFLLIVDYGFNLSATKKIAGERNKIKVSEIFWNVMACKLILTIICCV
                     ILFTLLEFSSYLYSQKSVIYSSFLIVISSVVFPVWLFQGKECLTLSSLISIGIKLLAV
                     PLIFIYVERPSDAWLAAMITSITSILGGIASLIIIWKRKWIGMIDISLKSIVFELKDA
                     WHVFLSSAAVNLYTSSVTVILGFICGPVAVGYFVAADKLRQAVQGLIIPFSQAFYPRI
                     TSLYIKNKKNAVGLIRKLLLLQSMGTLLLSLILFIIGRQSIDYLYGEEYINSYFVLII
                     FSFCPFLIGVSNVLGIQTMLVMGYKREFSKILIRSGIIGLLLVFPFSFAWGEYGAALV
                     IVISELTVTICMIKFVTKKKLLSVEG"
     gene            7058..8146
                     /gene="glf"
     CDS             7058..8146
                     /gene="glf"
                     /note="O034_07"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="BAQ00810.1"
                     /db_xref="GI:733166230"
                     /translation="MKMYDYIIVGAGLFGSICARELKKKNKKVLVLERREHVGGNIYT
                     EEKHGIHIHKYGAHIFHTNDKYIWDYVNSLVEFNRFTNSPIAFYKGKLYNLPFNMNTF
                     YQLWGTITPEQAQAKINEQRSEMLGKIPRNLEEQAISLVGRDVYEILIKGYTEKQWGR
                     KANELPAFIIRRLPVRFTFDNNYFSDKYQGIPIGGYTKLINVLLEGVDVKLNYDFLKN
                     RGEFKAKKIIYTGPIDEYYDFCFGKLDYRTLSFEHEILSIPDYQGNAVINYTEREVPF
                     TRIIEHKHFDPVDNDITIITKEYPREWTEGDEPYYPVNDEKNMQLFKKYRELALKENV
                     IFGGRLAEYKYYDMHQIIRSALNTVEKL"
     CDS             8156..9148
                     /note="O034_08"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf9"
                     /product="hypothetical protein"
                     /protein_id="BAQ00811.1"
                     /db_xref="GI:733166231"
                     /translation="MFSKIIVCCPGNLVTGGPELLHQFVHQLRLNYIDAEIIYYPFDR
                     DFETPNAYKHYNVKVVSLSGIDKCDNNLVILPETGTKYYKYFKGCQIGIWWLSVDNYF
                     GYAKKDSGFINNLKNLIKIFLRRKISLNKMQMMLHFYQSEYAREFLEKHHLQSIPLSD
                     YLNVNHLINEGRKENVFREKIITYNPKKGIKTTALLKSRFPSFRFKALCDMTPREVRE
                     YLEKSMVYIDFGNHPGKDRFPREAAMAGCVIITGRQGSAANNVDVPIPDMYKLDENSD
                     CFITDFEKLINSIFDDFETHTSIFREYREIISKEESKFKQDVELFIRKYISHYQ"
     gene            9183..10205
                     /gene="wzy"
     CDS             9183..10205
                     /gene="wzy"
                     /note="O034_09"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAQ00812.1"
                     /db_xref="GI:733166232"
                     /translation="MTNTNYIYNEFIFRCLFFFLISGLITLSTIKPEGFDHDYKQYLY
                     LFELYKNSIDLGFGYEVEPLFIYLSRLVNFFNGGIVALLFIYTAVALICKCIFIKRCT
                     KKTSQLVFFVFLYSVIFYPIHELTQIRISLALGLLLWGSLQKNKIIFAMIMLLTMLSH
                     YSLIPSVIFISLFRYLNDKIVRTQVLAFIALLCFVICLLLIFYMSRQTIKYDGTNMPF
                     YFYFLHPYSLIMLFSLFYMRRYIKNHFYYQLLYILAMLYYFLFLSFLFLQSQIAAFRF
                     MEIALFFMFILIFIINSSFKSSIIKMLMLILVVTMFLYEHVIAIEPILNFDILHNSFS
                     KMDTFQ"
     CDS             10202..11143
                     /note="O034_10"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf11"
                     /product="glycosyltransferase"
                     /protein_id="BAQ00813.1"
                     /db_xref="GI:733166233"
                     /translation="MIDIIMATYNGEEYIEAQIYSLLSQSFKNWNLYVYDDCSVDSTA
                     DIVKKIVGLDKRIHLIENKKNMGCALTFLNGIKKSNAEYVVLCDQDDLWFDNKLEVLF
                     DNIHSLDKTCPVLLFGRGYQYDQYTKKIIGRINMNSPNTLSDYLILNGGIQGCSMIMN
                     RSLINLITKYKCDVAMHDHFISTLAFSFGLVRAVDADLILYRKHNNNITSAIHGGMIN
                     KALKYIKSRKYFIDELHYDAINSIYESIKEDISISKRNEFELYLKLPRESKIKKIKYL
                     ISNRVRVSNSIVIPVILCLLQDSFGKNVKGELHRWEP"
     CDS             11131..12240
                     /note="O034_11"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf12"
                     /product="glycosyltransferase"
                     /protein_id="BAQ00814.1"
                     /db_xref="GI:733166234"
                     /translation="MGTMKDFDEVVFVISSQDGGGGPKATETIMDSLAEYNIKRDLYI
                     FNQRGRKNLSLINFFSAFRYIKRLSNNQKLIVFNSGGLGIGFLLNLIILILNVLFKRK
                     IKSVQIYHNRIFSVETNKLNNLIRLAISDLIILMSDAFICVSNGIRNEILRSGFFRKK
                     KKSCGYTIYNPLRSLNSSLKESHSLYPFEGPVILAVGRLCKQKGFDTLIKAHANILNT
                     VKAHLVIVGEGTEYSKLENLVRNYSDSDYVHFWGYDNNIANHYSSADVFVLSSIHEGF
                     GLVLLEAMSCGLPVISTNCPYGPEEILNFGEYGDIVNVSDIVGLSKSIIDVLNLPSDI
                     LQIRIKNGIERASEFSISNIGEQYIRLIKEFSFEE"
     CDS             12244..13341
                     /note="O034_12"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf13"
                     /product="glycosyltransferase"
                     /protein_id="BAQ00815.1"
                     /db_xref="GI:733166235"
                     /translation="MKILHLSKYYYPYSGGIEQVVQDICEGISSKYTCSVLALSESKK
                     YYESNLNGVQVYNCPVQFSISSASFSIKYISTLIKIIKDFDIIHIHLPNPLANIALML
                     AKEKNKKIIVHWHSDIVKQRYLEKIYRPFQNWLLKRTNLIIATSPAYVQGSRALFPFK
                     EKVNIIPIGVNKRNADDELTQLIKNKYGNKKIIFSLGRHVYYKGFENLIKAGMYLSSE
                     YIILIGGKGPLTSKYRELIDDLNCSDKVKLIGRIDERELPSYFSAADIFCLPSVERSE
                     AFGVVQIEAFSHEKPVVSCDIRGSGVSWVNKDAVSGLVVEVNKPKAIANAIDEIFSSY
                     EKYSKCAYLRYINLFTASGMNKKIITLYENI"
     gene            13372..14802
                     /gene="manC"
     CDS             13372..14802
                     /gene="manC"
                     /note="O034_13"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="BAQ00816.1"
                     /db_xref="GI:733166236"
                     /translation="MMIYPVIMAGGSGTRLWPLSRELYPKQFLKLDGDFTMLQTTISR
                     LNNLACENPLVLCNERHRFIVAEQLRGIGKLAKNIILEPEGRNTAPAIALAALTAIYL
                     AKDRESNPLILVLAADHIIKNYKVFSAAIQDAISFAQNDKLVTFGIVPNKIETAYGYI
                     KRGMQVNINDVNAYKVDSFKEKPDYDTAEEYLYSGEYYWNSGMFLFRAKRYLDELKKF
                     RPDILDACEKAMSAIDPDLDFIRVNEEAFLACPEESVDYAVMERTADAVVVPMDAGWS
                     DVGSWSSLWEISAHTAEGNVCHGDVINHKTENSYVYAESGLVTTVGVKDLVVVQTKDA
                     VLIADRNAVQDVKKVVEQIKADGRHEHRVHREVYRPWGKYDSIDAGDRYQVKRITVKP
                     GEGLSVQMHHHRAEHWVVVAGTAKVTIDGDIKLLGENESIYIPLGATHCLENPGKIPL
                     DLIEVRSGSYLEEDDVVRFADRYGRV"
     gene            14994..16364
                     /gene="manB"
     CDS             14994..16364
                     /gene="manB"
                     /note="O034_14"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="BAQ00817.1"
                     /db_xref="GI:733166237"
                     /translation="MKKLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLG
                     GDVRLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPM
                     DYNGMKLVREGARPISGDTGLRDVQRLAEANGFPPVDETKRGRYQQINLRDAYVDHLF
                     GYINVKNLTPLKLVINSGNGAAGPVVDAIEARFNALGAPVELIKVHNTPDGNFPNGIP
                     NPLLPECRDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLE
                     KNPGAKIIHDPRLSWNTVDVVTAAGGTPVMSKTGHAFIKERMRKEDAIYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVAELVCLKGKTLGELVRDRMAAFPASGEINSKLAQPVEAINR
                     VEQHFSREALAVDRTDGISMTFADWRFNLRSSNTEPVVRLNVESRGDVPLMEEKTKLI
                     LELLNK"
     gene            16528..17934
                     /gene="gnd"
     CDS             16528..17934
                     /gene="gnd"
                     /note="O034_15"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ00818.1"
                     /db_xref="GI:733166238"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            18183..19349
                     /gene="ugd"
     CDS             18183..19349
                     /gene="ugd"
                     /note="O034_16"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ00819.1"
                     /db_xref="GI:733166239"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIATPTDYDPETNYFNTSSVESVLK
                     DVVEINPYAVMVIKSTVPVGFTEAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNSRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELRDVADKVYTRDLFGSD"
     gene            19459..20472
                     /gene="wzz"
     CDS             19459..20472
                     /gene="wzz"
                     /note="O034_17"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ00820.1"
                     /db_xref="GI:733166240"
                     /translation="MRTWKFPSVRVMMRVENNNVSGQNHDPEQIDLIDLLVQLWRVKM
                     TIIISVIVAIALAIGYLAVAKEKWTSTAIITQPDVGQIAGYNNAMNVIYGQAAPKVSD
                     LQETLIGRFSSAFSALAETLDNQEEPEKLTIEPSVKNQQLPLTVSYVGQTAEGAQMKL
                     AQYIQQVDEKVNQELEKDLKDNIALGRKNLQDSLRTQEVVAQEQKDLRIRQIQEALQY
                     ANQAQVTKPQVQQTEDVTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQTRQNLLDI
                     ENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIALGRNALRNY
                     NAK"
     gene            complement(20570..21181)
                     /gene="hisI"
     CDS             complement(20570..21181)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ00821.1"
                     /db_xref="GI:733166241"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVNIAPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ"
BASE COUNT     6323 a   3957 c   4836 g   6354 t
ORIGIN
        1 tacgccaggg atttcataac cagattatcg atgccaacat caccaactgt aagttcagcg
       61 acttacaggg cgacgccatt gaatggaacg tggcaattaa cgacagtgat attttgatct
      121 ccgaccacat catcgagcgc atcaactgta ctaacggcaa aatcaactgg ggcattggca
      181 taggccttgc ggggagtacc tacgataata actacccgga agaccaggca gtgaaaaact
      241 ttgtcgtggc gaatatcacg ggatcggatt gtcggcagtt gatccatgtt gaaaatggca
      301 aacattttgt tatccgtaat atcaaagccc gcaatatcac gtcggatttc agtaagaaag
      361 caggtattga taacgccaca gtcgctattt acggttgtga caatttcgtg attgataata
      421 ttgaaatgat taatagcgcc gggatgttaa tcggctatgg ggtaattaaa ggcaaatatc
      481 tctcgatacc gcaaaatttc cgagtgaata atattcaact ggataacact caccttgctt
      541 ataaattgcg cggcatccaa atctccgccg ggaatgctgt ctcctttgtg gcactgacta
      601 acattgagat gaagcgtgcc tcgcttgagc tacacaataa accgcaacat ctttttatgc
      661 gaaatatcag agtgatgcag gaatcctcag ttggaccagc attgagcatg aactttgaca
      721 tgcgcaaaga cgttcgcggc gtgtttatgg cgaaaaaaga aacactgctg tctcttgcaa
      781 atgttcatgc ggtgaatgaa aaagggcaga gctccgtcga tatcgacagg attaatcacc
      841 atattgttaa tgtggaaaag attaacttta gattgccgga acggagagag tagatttgcg
      901 accattcctg gaaaaatgga gccatactta ggaacaatgc tactgcaatc cacaacgaag
      961 cggcgtaaca tcacaagtaa ttcagtaatc aattcagggt aattgatgct ggcgaaaaaa
     1021 atcgaacaag ctataattca gcaaccattt tacaggtgga tgaaataatg acgaatttaa
     1081 aagcagttat tcctgtagcg ggtcttggga tgcatatgtt gcctgccact aaggcgattc
     1141 ccaaagagat gctaccgatc gtcgacaagc caatgattca gtacattgtt gacgagattg
     1201 tggctgcagg gatcaaagaa atcctcctgg taactcacgc gtccaagaac gcggtcgaaa
     1261 accacttcga cacctcttat gaattagaat ctcttcttga gcagcgcgtg aagcgtcaac
     1321 tgcttgcgga agtgcagtcc atctgtccac cgggcgtgac cattatgaac gtgcgtcagg
     1381 gcgaaccttt aggtttaggc cactccattt tatgtgcacg acccgccatt ggtgacaatc
     1441 catttgtcgt ggtgctgcca gacgttgtga tcgatgacgc cagcgccgac ccgctgcgct
     1501 acaaccttgc ggccatgatt gcgcgcttca acgaaacggg ccgcagccag gtgctggcaa
     1561 aacgtatgcc gggtgacctc tctgaatact ccgtcattca gaccaaagaa ccgctggatc
     1621 gtgaaggtaa agtcagccgc attgttgaat ttatcgaaaa accggatcag ccgcagacgc
     1681 tggactcaga tattatggcc gttggtcgct atgtgctttc tgccgatatt tggccggaac
     1741 ttgaacgtac tcagcctggt gcatgggggc gtattcagct gactgatgcc attgccgaac
     1801 tggcgaaaaa acagtccgtt gatgcaatgc tgatgactgg tgacagctac gactgcggta
     1861 aaaaaatggg ctatatgcag gcgttcgtga agtatgggct gcgcaacctc aaagaagggg
     1921 cgaagttccg taaagggatt gagaagctgt taagcgaata atgaaaatct gaccggatgt
     1981 aacggttgat aagaaaatta taacggcagt gaagattcgt ggcgaaagta atttgttgcg
     2041 aatattcctg ccgttgtttt atataaacaa tcagaataac aacgagttag caataggatt
     2101 ttagtcaaag ttttccagga ttttccttgt ttccagagcg gattggtaag acaattagcg
     2161 tttgaatttt tcgggtttag cgcgagtggg taacgctcgt cacatcgtag gcatgcatgc
     2221 agtgctctgg tagctgtaaa gccaggggcg gtagcgtgca ttaatacctc tattaatcaa
     2281 actgagagcc gcttatttaa cagcatgctc tgaagtaata tggaataaaa gagtgaagat
     2341 acttgttact ggtggcgcag gatttattgg ttctgctgta gttcgtcaca ttataaataa
     2401 tacgcaggat agtgttgtta atgtcgataa attaacgtac gccggaaacc tggaatcact
     2461 tgctgatgtt tctgattctg aacgctatat ttttgaacat gcggatattt gcgatgctgc
     2521 tgcaatggca cggatttttg ctcagcatca gccggatgca gtgatgcacc tggcagctga
     2581 aagccatgtt gaccgttcaa ttacaggtcc tgcggcattt attgaaacca atattgttgg
     2641 tacttatgtc cttttggaag ccgctcgcaa ttactggtct gctcttgata gcgacaagaa
     2701 aaatagcttc cgttttcatc atatttctac tgacgaagtc tatggtgatt tgcctcatcc
     2761 agatgaagta aataataacg aagaattacc cttatttact gagacgacag cttacgcacc
     2821 aagcagccct tattccgcat caaaagcatc cagcgatcat ttagtccgcg cgtggaaacg
     2881 tacctatggt ttaccgacca ttgtgactaa ctgttcgaat aactacggtc cttatcactt
     2941 tccggaaaaa ttgattccac tagtaattct taatgctctg gaaggtaagg cattacctat
     3001 ttatggcaaa ggggatcaaa ttcgtgactg gctgtatgtt gaagatcatg cgcgtgcgtt
     3061 atataccgtc gtaaccgaag gtaaagcggg tgaaacttat aacattggtg gacacaacga
     3121 aaagaaaaac atcgatgtag tgctcactat ttgtgatttg ttggatgaga ttgtaccgaa
     3181 agagaaatct tatcgtgagc aaattactta tgttgccgac cgcccgggac atgatcgccg
     3241 ttatgcgatt gatgctgaga agattagccg cgaattgggt tggaaaccac aggaaacgtt
     3301 tgagagcggg attcgtaaaa cagtggaatg gtacctgtcc aatacaaaat gggttgataa
     3361 tgtgaaaagt ggtgcctatc aatcgtggat tgaacagaac tatgagggcc gccagtaatg
     3421 aatatcctcc ttttcggcaa aacagggcag gtaggttggg aactacagcg tgctctggca
     3481 cctctgggta atttgattgc tcttgatgtt cactccactg attactgtgg tgattttagt
     3541 aatcctgaag gtgtagctga aaccgtaaga agcattcggc ctgatattat tgtcaacgca
     3601 gcagctcaca ccgcagtaga caaagcagaa tcagaaccgg agtttgcaca attacttaac
     3661 gcgacgagtg tcgaagcgat cgcgaaagca gccaatgaag tcggcgcatg ggttattcac
     3721 tactctactg actacgtatt tccggggacc ggtgaaatac catggcagga ggcggatgca
     3781 accgcaccgc taaatgttta cggtgaaacc aagttagctg gagaaaaagc attacaggaa
     3841 cattgcgcga agcatcttat tttccgtacc agctgggtat acgcaagtaa aggaaataac
     3901 ttcgccaaaa cgatgttgcg tctggcaaaa gagcgcgaag aactggctgt gattaatgat
     3961 caatttggtg cgccaacagg tgctgagctg ctggcagatt gtacggcaca tgcaattcgt
     4021 atggcactga ataaaccaga agtcgcaggc ttgtaccatc tggtagccag tggtaccaca
     4081 acctggcacg attatgctgc gctggttttt gaagaggcac gcaaagcagg tattcccctt
     4141 gcactcaaca agctcaacgc agtaccaaca acagcttatc ctacaccagc tcgtcgtcca
     4201 cataactctc gccttaatac agaaaaattt cagcagaact ttgcgcttgt cttgcctgac
     4261 tggcaggttg gtgtgaaacg aatgctcaac gaattattta cgactacagc aatttaatag
     4321 tttttgcatc ttgttcgtga tggtggagca agatgaatta aaaggaatga tgaaatgaaa
     4381 acgcgtaaag gtattatttt agcgggtggt tctggtacac gtctttatcc tgtgactatg
     4441 gctgtcagta aacagctatt acctatttat gataagccga tgatctatta cccgctctct
     4501 acactgatgt tggcgggtat tcgcgatatt ctgattatta gtacgccaca ggatactcct
     4561 cgttttcaac aactgctgag tgacggtagc cagtgggggc taaatcttca gtacaaagtg
     4621 caaccgactc cagatgggct tgcgcaggcg tttattatcg gtgaagagtt tatcggtggt
     4681 gatgattgtg ctttggtact tggtgataat atcttctacg gtcacgacct gcctaagtta
     4741 atggatgccg ctgttaacaa agaaaatggt gcaacggtat ttgcctatca cgttaatgat
     4801 cctgaacgct acggtgtcgt tgagtttaat aaaaacggta cggcaattag cctggaagaa
     4861 aaaccgctac agccaaaaag taattatgcg gtaactgggc tttattttta tgataacgac
     4921 gttgtcgaaa tggcgaaaaa tcttaagcct tctgcccgtg gtgaactgga aattaccgat
     4981 attaaccgta tctatatgga acaggggcgt ttatccgttg ccatgatggg acgtggttat
     5041 gcatggctgg acacggggac acatcaaagt cttattgaag caagcaactt cattgcaaca
     5101 attgaagagc gccaggggct gaaagtttcc tgcccggaag aaattgctta ccgtaaaggg
     5161 tttattgatt ctggacaggt tagggtatta gccgagccac ttaagaaaaa tgcttatggt
     5221 caatatctgc tgaaaatggt taaaggttat taataaaatg aatgtaatta aaactgaaat
     5281 tccagatgta ttaatatttg aaccaaaagt atttggggat gagcgtggtt tctttatgga
     5341 aagctttaat cagaaagttt tcgaagaggc tgtagggcgg aaggttgaat ttgttcagga
     5401 taaccattcg aagtcttgta aaggtgtttt acgcggactg cattatcagt tagagcctta
     5461 tgcgcaagga aaactggttc gctgcgtcgt tggtgaagtt tttgacgtag cggttgatat
     5521 tcgtaaatcg tcacctacct ttggcaaatg ggttggggtg aatttatctg ctgagaataa
     5581 gcgccagttg tggatacctg aaggatttgc gcatggattt ttggtattga gtgaggttgc
     5641 tgagtttgtt tataagacga ataattttta ctcgcctgaa tgtgagagaa caataaaatg
     5701 ggacgataat gatttaaata ttaaatggcc gctacagtta attgacaatg ttattgtgtc
     5761 ggataaagat aataaaggca atgctttgat ggtctcagat taatatgaaa tttattaact
     5821 tggataaaag attaactagt aatattatat ctttatgttt agtgcaaggg gccggttata
     5881 taataccact attaacttta ccatatttgg tgaaaacttt aggtccggtt tcatatggtg
     5941 tgttgggttt ttcaatagca tttactcaat attttcttct tattgttgat tatgggttta
     6001 atctgtctgc aacgaaaaaa atagcaggtg agagaaataa aataaaggta agtgaaatat
     6061 tttggaatgt catggcgtgt aaacttatac taactataat ttgctgtgtg atccttttca
     6121 ctcttttaga gttttcatct tatctttact cacaaaaaag cgtgatatat tccagttttt
     6181 taattgtgat tagtagtgtg gtatttcctg tatggttatt tcagggtaag gaatgtttaa
     6241 cgttatcatc tttaatatca ataggcatta aattactggc tgtgcctttg atatttatat
     6301 atgtggaaag gccatcagat gcatggcttg ctgcaatgat aacatcaata acatcgatat
     6361 tgggggggat agcctcatta attataatat ggaaaagaaa atggatcggg atgattgata
     6421 tttcgttaaa atcaatagtg tttgaattaa aagatgcgtg gcatgttttt ctttcatcgg
     6481 cagcagtaaa tttatatact tcaagtgtta ctgtgatatt agggtttatt tgcggccctg
     6541 ttgcggttgg ttattttgtg gctgctgata aattacgaca agccgtacag gggcttatta
     6601 ttccgttttc acaggcattc tatcctagaa taacatcctt atatataaaa aataaaaaaa
     6661 atgcagtagg tttaattaga aagttgttgc ttctccaaag tatggggact ttattgttaa
     6721 gtcttatact tttcatcatt ggcaggcaat cgatagatta tttatatggg gaagagtata
     6781 taaattctta ttttgtattg attattttct cattttgtcc gtttttgatt ggggttagta
     6841 atgtgttagg tatacaaact atgctcgtaa tgggatataa aagagaattt agcaaaattt
     6901 tgatacggtc agggattatt ggccttttat tggtttttcc attctctttt gcatggggag
     6961 aatatggcgc agcgttggtt attgttattt cagagttgac agtaactata tgtatgatta
     7021 aattcgtcac aaagaagaaa ttactatctg tagagggttg aaaatgtacg attatattat
     7081 tgttggagct gggttgttcg gttctatatg cgcaagagaa ctaaaaaaga aaaataagaa
     7141 agtcctggtg cttgagcgga gagagcatgt aggtggaaat atttatacgg aggaaaaaca
     7201 tggtattcat attcataaat atggggctca tatttttcat acaaacgata aatacatatg
     7261 ggattatgta aactcattag ttgaatttaa tagatttaca aattccccaa tagcatttta
     7321 taaaggcaaa ttatataacc ttccctttaa tatgaataca ttttatcaat tgtgggggac
     7381 tattacaccg gagcaagctc aagctaagat taatgaacag cgttcggaaa tgttaggtaa
     7441 aataccaaga aatctagaag agcaagctat atctctagta ggaagagatg tatacgaaat
     7501 tctaataaaa ggatatacgg aaaaacaatg gggacgaaag gctaatgaac tcccggcatt
     7561 tattattaga cgtttaccag tgaggtttac tttcgacaat aattattttt ctgataaata
     7621 tcaaggaata cctattggag gttatacgaa gctcataaat gttttgttgg agggggttga
     7681 tgttaagtta aattatgact ttctaaagaa taggggcgag tttaaggcca aaaaaattat
     7741 atatactggg ccaattgatg agtattatga tttttgtttt gggaaattgg attatcgtac
     7801 actctcattt gagcatgaga tactatctat tcctgactat caaggaaatg ctgttataaa
     7861 ttatactgaa agagaagttc catttactcg tattattgag cataaacact tcgatccagt
     7921 tgataatgat attacgatta ttacaaaaga atatcccaga gaatggactg aaggtgatga
     7981 gccatattat ccggttaatg atgaaaagaa tatgcagtta ttcaagaagt atagagaact
     8041 tgcactaaaa gaaaatgtta tatttggtgg gcgccttgct gagtacaagt attatgatat
     8101 gcatcaaata attcgttcgg cattaaatac agttgagaag ttataaggag gggagatgtt
     8161 ttctaagatt atagtatgct gtcctggaaa ccttgttact ggtggacctg agttgttaca
     8221 tcagtttgta catcaattac ggttaaatta cattgatgct gaaataatat attatccttt
     8281 tgatcgagat tttgaaacac ctaatgcgta caagcattat aatgtcaaag ttgtttctct
     8341 atcaggcatc gataaatgtg acaataattt agtaatattg cccgaaactg gtactaaata
     8401 ttataaatat tttaagggat gccaaatagg tatttggtgg ttatctgtcg ataactattt
     8461 tggttatgca aaaaaagatt ctggttttat taataatcta aagaacttaa ttaagatttt
     8521 tttacgtagg aagatttctc ttaataagat gcaaatgatg ttacactttt atcaaagtga
     8581 atatgcgcgg gaatttttag aaaaacacca cttacaatca atacctttgt ctgattattt
     8641 aaatgtaaat catcttatta atgaaggaag aaaggagaat gtgttcaggg aaaagattat
     8701 tacttataat cctaaaaaag ggattaaaac tacggcttta ctcaaaagta gatttccatc
     8761 gtttaggttc aaggcattgt gtgatatgac accgagagaa gttagggaat atcttgaaaa
     8821 aagtatggta tatatagatt tcggaaatca tccaggtaaa gatagatttc cacgtgaagc
     8881 tgcaatggct ggttgcgtca tcataactgg aagacaaggt agcgctgcta ataatgtaga
     8941 tgtccctatc ccagatatgt ataaacttga tgagaatagt gattgtttta taaccgattt
     9001 cgagaaatta attaatagca tattcgatga tttcgaaaca catacaagta tattcagaga
     9061 gtatagagaa ataatcagta aagaagaaag taaatttaaa caagatgtag agttatttat
     9121 aaggaaatac atttctcatt atcaataatt ttatattgtt aatattaatt aagaactatg
     9181 tgatgacaaa tacgaattat atctataatg aatttatatt tcgatgcctt ttcttttttc
     9241 ttatatctgg gctgattact ttgtccacta taaaaccaga aggatttgat catgattaca
     9301 aacagtatct gtatctattt gagttgtata aaaatagtat agacctagga tttggatatg
     9361 aagttgaacc attatttatt tatttgtcaa gattagtaaa tttctttaat ggggggattg
     9421 tagcattatt gttcatttat actgcagtag ctcttatatg taaatgtatt tttattaaga
     9481 gatgtacaaa aaaaacatct cagcttgtat tttttgtttt tttatattca gtcatttttt
     9541 atccaattca tgagttaact caaattagaa tttccttggc tttaggtctg cttctgtggg
     9601 ggagtttaca gaaaaataaa attatttttg cgatgatcat gttattaaca atgctaagcc
     9661 attattcctt gattccttct gtgatattca tttcattatt taggtatcta aatgataaaa
     9721 ttgtgcgcac acaggtttta gcatttatag cattattatg ttttgttatt tgtctgcttt
     9781 tgatttttta tatgagtagg cagactatta aatatgatgg cacgaatatg ccattttatt
     9841 tttatttctt gcatccttat tcattaatca tgttattttc attattttat atgaggcgtt
     9901 acataaagaa tcatttttat tatcagcttc tttatatttt ggctatgctc tattattttt
     9961 tatttttatc ctttcttttt cttcagagcc aaattgctgc ctttagattt atggaaattg
    10021 ctttattttt catgtttata ttaattttta ttattaattc ttcttttaag tcttctataa
    10081 taaaaatgtt aatgctaatt cttgttgtta ctatgttttt gtatgaacac gtaatagcga
    10141 ttgagcctat attgaacttt gatatactac ataatagctt ttctaaaatg gatacttttc
    10201 aatgattgat ataataatgg caacttacaa tggcgaggaa tatattgaag ctcagatata
    10261 ttcgttgctt tctcaaagtt ttaaaaattg gaacttatat gtatatgatg attgctcagt
    10321 tgatagtact gctgatatag ttaaaaaaat cgtaggtcta gataagagaa ttcatcttat
    10381 cgaaaataaa aaaaacatgg gatgtgcttt gacgttttta aatggtataa aaaaaagtaa
    10441 tgcagagtac gttgtcttat gtgatcagga tgatctttgg tttgacaata agctagaggt
    10501 gttatttgac aatattcata gtttggataa aacttgtcca gtgttattgt ttgggcgagg
    10561 ataccaatat gatcaatata ctaaaaagat aataggtaga attaacatga atagcccgaa
    10621 taccctaagt gattatttga ttcttaatgg tggtattcaa ggttgttcaa tgattatgaa
    10681 tagatcttta attaatttaa ttaccaaata taaatgcgat gttgctatgc atgatcattt
    10741 tatatctacc ttagcatttt cgtttggctt ggttcgtgct gttgatgctg atcttatttt
    10801 atatagaaaa cataacaaca acataacatc tgcgatacat ggtggaatga ttaataaagc
    10861 actaaaatat atcaaatcac gaaaatactt tattgatgaa ttacattatg atgctataaa
    10921 ttctatttat gagagtataa aagaggatat ttcaatatct aagagaaatg agtttgaatt
    10981 gtatctgaaa ttacccagag aaagtaaaat aaaaaagatt aaatatttaa tatcaaacag
    11041 ggtaagagtt agtaatagta ttgtgattcc tgttatatta tgtctgctac aagattcttt
    11101 tggtaaaaat gtgaaaggtg aattacatag atgggaacca tgaaagattt tgacgaagtt
    11161 gtttttgtta tttcctctca agatggaggt ggtggaccta aagcaacaga aacaataatg
    11221 gactctttag ctgaatacaa tataaaaagg gatttgtata tatttaatca gagaggaagg
    11281 aaaaatttat cattgataaa ttttttttcc gcttttagat atattaaaag attaagtaat
    11341 aatcaaaagc ttattgtatt caatagtggt gggcttggga tcgggtttct attgaatctt
    11401 attatattaa ttttaaatgt attgttcaaa cgaaaaatta aatccgttca gatatatcat
    11461 aataggattt tttcagtaga aactaataag ctaaataatc ttataagatt agctatttct
    11521 gaccttatca tattaatgtc tgatgcattt atttgtgttt caaatgggat acgaaatgaa
    11581 atactccgct cgggcttttt tcgaaagaaa aaaaaatcct gtggttatac gatttataat
    11641 cctctgcgaa gcctcaactc aagtttaaaa gaaagccact cattataccc atttgaaggc
    11701 cctgttattt tagctgttgg taggttatgt aaacaaaaag gatttgatac tttaattaaa
    11761 gcccatgcaa atatactaaa cactgttaaa gctcatctcg taattgttgg tgaaggtacc
    11821 gaatattcta aacttgaaaa tttagtaaga aattattcag attctgatta tgtacatttc
    11881 tggggatatg ataataatat agcgaatcat tattcatctg cggatgtttt tgttttatcc
    11941 tcaattcatg aaggatttgg tttggtatta ttagaagcaa tgtcctgtgg tctccctgta
    12001 atttcaacga attgtcctta tgggccagag gaaatattaa attttggcga gtatggtgat
    12061 attgtaaatg ttagtgatat agttggatta tccaaaagta ttattgatgt gttaaatttg
    12121 ccaagtgata ttttacagat cagaataaag aacggaattg agcgtgcgtc agagttttcg
    12181 attagcaata taggtgaaca atatataagg ttaattaagg aattttcttt tgaggagtaa
    12241 acattgaaaa tattacattt aagtaagtat tattatcctt atagtggtgg aatagagcaa
    12301 gttgtacagg atatatgcga aggtattagc tctaaatata catgctcagt tttggcttta
    12361 tcagaatcta aaaaatatta cgagagtaat ttgaatgggg ttcaggtata caattgccct
    12421 gtgcaatttt ctatatcgtc agcaagtttt tctataaagt atatttccac actaataaag
    12481 ataataaaag attttgatat aatccatata catcttccta atccattagc taatattgca
    12541 ttaatgttgg ccaaagaaaa gaataaaaaa ataatagttc attggcatag tgatatagtt
    12601 aagcagcgat atcttgagaa aatatatcgc ccgtttcaaa attggctctt aaaacgaacc
    12661 aatttaataa tcgctacatc tcccgcatat gtacaaggat ctcgtgcatt atttcctttt
    12721 aaagaaaaag taaatattat tccaatagga gttaacaaga gaaacgctga tgacgagtta
    12781 actcaactga taaaaaataa atatggaaat aaaaaaataa tcttctcact tggaagacat
    12841 gtgtattaca aaggatttga gaatttaatt aaggctggaa tgtatctttc atccgaatat
    12901 atcattttaa ttggagggaa aggcccactt acaagcaagt atcgtgagct tattgatgac
    12961 cttaattgta gtgataaagt aaaattaatt ggacgtattg atgagagaga attacctagc
    13021 tacttttctg ctgcggatat tttttgcttg ccttcagttg aacgctctga agcatttggg
    13081 gttgttcaaa ttgaagcctt ttcccatgaa aaaccagtag tttcttgtga tataagaggt
    13141 tcaggggtca gttgggtcaa taaagacgca gtttccggat tagtagttga ggtaaataaa
    13201 ccaaaggcta ttgctaatgc gatcgatgaa atattttcat cttatgaaaa atattcaaaa
    13261 tgtgcttatt taagatatat caatttattt acggcgagtg gtatgaataa aaaaattatt
    13321 actttgtatg aaaatattta aaatcgtata tgaattattt taacggagat attgatgatt
    13381 tatccagtaa tcatggcagg tggttcaggt actagacttt ggccattatc aagagaactt
    13441 tatcctaaac agttcctaaa gttagatggt gatttcacca tgctacagac tacaatatct
    13501 cgacttaata atcttgcctg tgagaatccc ttagttcttt gtaacgagcg gcaccgattt
    13561 attgttgctg aacaactgag agggatagga aaattagcta agaatataat tcttgagcct
    13621 gaggggcgga atactgcacc tgcgatagct ttggctgcat taactgcaat ttatttggca
    13681 aaagatagag aatctaaccc tcttatatta gttctggcag ctgatcatat aattaaaaac
    13741 tataaggtgt tttctgctgc gattcaagat gcaatatctt ttgcgcaaaa tgataagttg
    13801 gttacttttg gaattgttcc taataagata gaaacagcat acggctatat taagcgtggt
    13861 atgcaggtaa acatcaatga tgttaatgca tacaaagtgg actcttttaa agaaaaacca
    13921 gattatgata ctgctgaaga atatttgtac agcggtgagt attactggaa tagtggtatg
    13981 ttcttatttc gtgcaaagcg ttatcttgac gaattaaaaa aatttcgtcc ggatattctc
    14041 gatgcctgtg aaaaagcgat gagcgccatc gatccggatc tcgattttat tcgtgtgaat
    14101 gaagaagcgt ttctggcctg cccggaagag tcggtggatt acgcggtcat ggaacgtacg
    14161 gcagatgccg ttgtggtgcc gatggatgcg ggctggagcg atgtcggctc ctggtcctct
    14221 ttatgggaaa tcagcgccca caccgccgag ggcaacgttt gccatggcga tgtgattaat
    14281 cacaaaactg aaaacagcta tgtgtatgcc gaatctggcc tcgtaaccac cgtcggggtg
    14341 aaagatctgg tagtggtgca gaccaaagat gcggtgctga ttgccgaccg taacgcggtg
    14401 caggatgtga aaaaagtggt cgagcagatc aaagccgatg gtcgccatga gcatcgggta
    14461 catcgcgaag tctatcgccc gtggggcaaa tatgactcta tcgacgcggg cgaccgctac
    14521 caggtgaaac gcatcaccgt gaaaccgggc gaaggcttgt cggtacagat gcaccatcac
    14581 cgcgcggaac actgggtggt ggtcgcagga acggcaaaag tcactattga cggtgatatc
    14641 aaactgcttg gtgaaaacga gtccatttat attccgctgg gggcgacgca ctgcctggaa
    14701 aacccgggga aaattccgct cgatttaatt gaagtgcgct ccggctctta tctcgaagag
    14761 gatgatgtgg tgcgcttcgc ggatcgctac ggacgggtgt aaacgtcgca tcaggcgctg
    14821 tttgtcggat gcggcgtgaa cgccttatcc gacctacggt tcggttttgt aggcctgata
    14881 agacgcggag cgtcgcatca ggcaatgaat gcgaaaccgc ggtgtaaata acgacaaaaa
    14941 caaaattggc cgtttcggtc agggccaact attgcctgaa aaagggtaac aacatgaaaa
    15001 aattaacctg ctttaaagcc tatgatattc gcgggaaatt aggcgaagaa ctgaatgaag
    15061 atatcgcctg gcgcattggt cgcgcctatg gcgaatttct caaaccgaaa accattgtgt
    15121 taggcggtga tgtccgtctc accagcgaaa ccttaaaact ggcgctggca aaaggtttac
    15181 aggatgcggg cgttgacgtg ctggatattg gtatgtccgg caccgaagag atctatttcg
    15241 ccacgttcca tctcggcgtg gatggcggca ttgaagttac cgccagccat aatccgatgg
    15301 attataacgg catgaagctg gttcgcgagg gggctcgccc gatcagcgga gataccggac
    15361 tgcgcgacgt ccagcgtctg gctgaagcca acggctttcc tcccgtcgat gaaaccaaac
    15421 gcggtcgcta tcagcaaatc aacctgcgtg acgcttacgt tgatcacctg ttcggttata
    15481 tcaatgtcaa aaacctcacg ccgctcaagc tggtgatcaa ctccgggaac ggcgcagcgg
    15541 gtccggtagt tgacgccatc gaagcccgct ttaacgccct cggtgcaccc gtggaattaa
    15601 tcaaagtgca caacacgccg gacggcaatt tccccaacgg tattcctaac ccgctgctgc
    15661 cggaatgccg cgacgacacc cgcaatgcgg tcatcaaaca cggcgcggat atgggcattg
    15721 cttttgatgg cgattttgac cgctgcttcc tgtttgacga aaaagggcag tttattgagg
    15781 gctactacat tgtcggcctg ttggcagaag cattcctcga aaaaaatccc ggcgcgaaga
    15841 tcatccacga tccacgtctc tcctggaaca ccgttgatgt ggtgaccgcc gcgggcggca
    15901 ctccggtgat gtcgaaaacc ggacacgcct ttattaaaga acgtatgcgc aaggaagacg
    15961 ccatctacgg tggcgaaatg agcgcccacc actatttccg tgatttcgct tactgcgaca
    16021 gcggtatgat cccgtggctg ctggtcgccg aactggtgtg tctgaaagga aaaacgctgg
    16081 gcgaactggt gcgcgaccgg atggcggcgt ttccggcaag cggtgagatc aacagcaaac
    16141 tggcgcaacc cgttgaggcg attaaccgcg tggaacagca ttttagccgt gaggcgctgg
    16201 cggtggatcg caccgatggt atcagcatga cctttgccga ctggcgcttt aacctgcgct
    16261 cctccaacac cgaaccggtg gtgcggttga atgtggaatc gcgcggtgat gtgccgctga
    16321 tggaagaaaa gacaaaactt atccttgagt tactgaacaa gtaattcagt aatttcatat
    16381 aaatgggttt taaaaaacgg aaaagatgag atatccggtg tggtatagcc aaggtaatgc
    16441 tattcagtat ctctatgagt gagttaacat ctataccaca tttaagccgc acacttcgcg
    16501 gtgaccaccc cctgacagga gtaaacaatg tcaaagcaac agatcggcgt cgtcggtatg
    16561 gcagtgatgg ggcgcaacct tgcgctcaac atcgaaagcc gtggttatac cgtctctatt
    16621 ttcaaccgtt cccgtgaaaa gacggaagaa gtgattgccg aaaatccagg caagaaactg
    16681 gttccttact atacggtgaa agagtttgtt gaatctctgg aaacgcctcg tcgcatcctg
    16741 ttaatggtga aagcaggtgc aggcacggat gctgctattg attccctcaa accatatctc
    16801 gataaaggcg acatcatcat cgatggtggt aacaccttct tccaggacac cattcgtcgt
    16861 aaccgtgagc tttctgccga aggctttaac ttcatcggta ccggtgtttc cggcggagaa
    16921 gagggggcgc tgaaagggcc gtccatcatg cctggtggcc agaaagaagc ctatgaactg
    16981 gttgcgccga tcctgaccaa aatcgccgcc gttgctgaag atggcgaacc gtgcgttacc
    17041 tatatcggtg ctgatggcgc aggccattat gtgaagatgg ttcacaacgg tatcgaatac
    17101 ggtgatatgc agctgattgc tgaagcctat tctctgctta aaggcggcct gaatctctct
    17161 aacgaagaac tggcacagac ctttaccgag tggaataacg gtgaactgag cagctacctg
    17221 atcgacatca ccaaagacat cttcactaaa aaagatgaag acggtaacta cctggttgat
    17281 gtgatcctgg atgaagcggc taacaaaggt accggtaaat ggaccagcca gagcgcgctg
    17341 gatctcggag aaccgctgtc gctgattacc gagtctgtgt ttgcacgtta tatctcttct
    17401 ctgaaagatc agcgtgttgc cgcgtctaaa gttctctctg gtccgcaagc gcagcctgct
    17461 ggcgacaagg ctgagttcat cgaaaaagtt cgtcgtgctc tgtatctggg caaaatcgtt
    17521 tcttacgccc aaggcttctc tcagctgcgt gctgcgtctg aagagtacaa ctgggatctg
    17581 aactacggcg aaatcgcgaa gattttccgt gctggctgca tcatccgtgc gcagttcctg
    17641 cagaaaatca ccgatgctta tgccgaaaat ccgcagatcg ctaacctgct gctggctccg
    17701 tacttcaagc aaattgccga tgactatcag caggcgctgc gcgatgtcgt cgcttatgca
    17761 gtacagaacg gtatcccggt tccgaccttc gccgctgcgg ttgcctatta cgacagctac
    17821 cgtgccgctg ttctgcctgc gaacctgatc caggctcagc gtgactattt tggtgcgcat
    17881 acttataagc gcattgataa agaaggtgtg ttccatactg aatggctgga ttaatctgat
    17941 ttaaccaaca ataaattgag gcccggcgta tattacgccg ggcttttttt ttgccaatta
    18001 tcttatagac taaatttcac tgcttaatat taacttaata aatatcagct attcttataa
    18061 agaaaatctg aattgttttt cgttgcgttg accatcgaac aacgtagcgt taaaactttt
    18121 agctcttatc aggatgctaa aaacatcatg attcacagtt aagttaattc tgagagcatg
    18181 aaatgaaaat caccatttcc ggtaccggct atgtaggctt gtcaaacggg cttctaatcg
    18241 cacaaaatca tgaggttgtg gcattagata ttttaccgtc acgcgttgct atgctgaatg
    18301 atcggatatc tcctattgtt gataaggaaa ttcagcagtt tttgcaatca gataaaatac
    18361 actttaatgc cacattagat aaaaatgaag cctaccggga tgctgattat gtcatcatcg
    18421 ccactccaac cgactatgat cctgaaacta attatttcaa tacatccagt gtagaatcag
    18481 tacttaaaga cgtagttgag ataaatcctt atgcggttat ggtcatcaaa tcaacggttc
    18541 ccgttggttt taccgaagcg atgcataaga aatatcgtac tgaaaatatt attttctctc
    18601 cggaatttct ccgtgaaggt aaagcccttt acgataatct ccatccttca cgtattgtca
    18661 taggtgagcg ttcagaacgc gcagaacgtt ttgctgcgtt gttacaggaa ggcgcgatta
    18721 agcaaaatat cccgaccctg tttaccgact ccactgaagc agaagcgatt aaactttttg
    18781 caaacaccta cctcgcgatg cgcgtggcgt actttaacga actggatagc tacgcagaaa
    18841 gtttaggtct gaattcccgt caaataatcg aaggcgtttg tctcgaccca cgtattggca
    18901 accattacaa caatccgtcg tttggttatg gtggttattg tttgccgaaa gataccaagc
    18961 agttactggc gaactaccag tctgtgccga ataacctgat ctcggcaatt gtcgatgcta
    19021 accgcacgcg taaagatttt attgccgatg ccattttgtc acgcaagccg caagtggtag
    19081 gtatttatcg tctgattatg aagagcggtt cagataactt ccgtgcgtct tctattcagg
    19141 ggattatgaa gcgtatcaag gcgaaaggcg ttgaagtgat catctacgag ccagtgatga
    19201 aagaagactc attcttcaac tctcgcctgg aacgtgatct cgccaccttc aaacaacaag
    19261 ccgacgtcat tatttccaac cgtatggcag aagagcttag ggatgtggca gataaggtct
    19321 acacccgcga tctctttggc agcgactaac atcttgttat cagggctatt tacgccctga
    19381 ttgtcttttg ttacttacgc aacaattcat tatttttatc acttatccta tagcattcac
    19441 ggggattatc gctaaactat gcggacttgg aaatttccgt cagttagggt aatgatgaga
    19501 gtagaaaata ataatgtttc tgggcaaaac catgacccgg aacagattga tttgattgat
    19561 ttactagtgc agttgtggcg tgtcaagatg acaatcatca tttccgtcat tgtagctatt
    19621 gccctggcta ttggttattt ggcagtagcg aaggagaaat ggacgtcaac agcaattatc
    19681 actcagcccg acgtggggca aattgctggc tataacaatg ccatgaatgt tatctatggt
    19741 caggctgcac cgaaagtatc ggatttgcag gagacgttaa ttggtcgctt cagttctgcc
    19801 ttctctgcat tagcagaaac gctggataat caggaagagc cagagaaact taccatcgaa
    19861 ccttctgtta agaaccagca attaccattg actgtttctt atgttgggca aacagcagag
    19921 ggcgcacaaa tgaagttggc ccaatacatt cagcaagttg atgaaaaagt gaatcaagag
    19981 ctagaaaagg atctcaaaga caacattgct ctgggacgga aaaacttgca ggactcttta
    20041 agaactcagg aagtagtcgc gcaggagcag aaagatctgc gtatccgtca gattcaggaa
    20101 gcattgcagt atgcgaatca ggcgcaggtg acaaaaccac aggttcagca gactgaagat
    20161 gtgacgcaag atacgttgtt ccttttgggg agcgaagcgc tggagtcgat gattaagcat
    20221 gaggcgaccc gtccgttggt gttctcacca aactactatc agactcgtca aaacctgctg
    20281 gatatcgaaa acttaaaggt tgatgatctt gatatccatg cttaccgcta tgtgatgaaa
    20341 ccgacgttac ctattcgtcg cgatagcccg aaaaaggcaa ttaccttgat tctggcagtc
    20401 ctgctgggcg gcatggttgg cgcggggatt gcgctggggc gtaacgctct acgcaattac
    20461 aacgcgaaat aatctttgca gttttaaaga aaacgggcag agtggtgaca ccttgcccgt
    20521 ttttttttgc cggatgcgac tacaacatcg catccggtca gtccgcaact cactgatgcc
    20581 gtttacgcag gttctcaatc accgttgtta aatccagatc ctgatcctgc aacaatacca
    20641 gcaggtgata catcaaatca gatgcctcgt tagttagttc aaagcggtca tgtaccgttg
    20701 ctgccagtgc ggtttccacc ccttcttcgc ccactttctg cgcaatgcgt ttggtgccgc
    20761 tggcatacag tttggctgtg taagaggttt ccgggtcggc agatttacgt tcggcgagca
    20821 gttgttccag ttgatacagg aacagccact ggtgagcggt gtcgccgaag cagctgctgg
    20881 tgcctttgtg gcaggttgga ccgatgggat tagccagcac taataaagtg tcgttgtcgc
    20941 agtccggcgc aatatttact acgttgagga aattgcccga cgtttcgcct ttggtccaca
    21001 gtcgctgttt agtgcgcgag aagaaggtga ctttgccgct ttcgatggtt ttgtctaagg
    21061 cttccgggtt catatagccc agcattaaca cttcgccgga taccgcgtgt tgcacaatca
    21121 ccggcatcag tccgtcggtt ttttcccagt ccagttcgcg acgttgttgt tctgttaaca
    21181 tatcctgatc tccacgccct gtgttgccag gtacgctttt aattcaccaa tattgattat
    21241 ttgtttgtgg aatacggaag ctgccagcgc gccgtcaacg tcggcatcgc ggaaggcttc
    21301 gaggaagtgt tccatggtgc ccgcgccacc ggaggcaatc agcgggacgt ggcaaacttc
    21361 acgcactttt ttcagctgct cgaggtcgta accgttacgc acaccgtcct gattcatcat
    21421 gttgaggacg atttctccgg caccgcgttt ttgcactttc tgtacccagt
//
