LOCUS       AB811622               19477 bp    DNA     linear   BCT 13-DEC-2014
DEFINITION  Escherichia coli DNA, O-antigen biosynthetic locus, strain: U8-41.
ACCESSION   AB811622
VERSION     AB811622.1  GI:733166393
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. (2014) In press
   PUBMED   25428893
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 19477)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..19477
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="U8-41"
                     /db_xref="taxon:562"
                     /note="serogroup:O48"
     gene            <1..857
                     /gene="wcaM"
     CDS             <1..857
                     /gene="wcaM"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="BAQ00964.1"
                     /db_xref="GI:733166394"
                     /translation="ITNCKFSDLQGDAIEWNVAINDHDILISDHVIERINCTNGKINW
                     GIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGKHFVIRNIKARNITP
                     DFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGKYLSIPQNFRVNNIQ
                     MDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQHLFMRNIKVMQESSV
                     GPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNEKGQSSVDIDRINHHIVNVEKIN
                     FRLPERRE"
     gene            1020..1925
                     /gene="galF"
     CDS             1020..1925
                     /gene="galF"
                     /note="O048_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ00965.1"
                     /db_xref="GI:733166395"
                     /translation="MDEIMTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVT
                     IMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGR
                     YVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQA
                     FVKYGLRNLKEGAKFRKGIEKLLSE"
     gene            2298..3383
                     /gene="rmlB"
     CDS             2298..3383
                     /gene="rmlB"
                     /note="O048_02"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6 dehydratase"
                     /protein_id="BAQ00966.1"
                     /db_xref="GI:733166396"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLA
                     DVSDSERYVFEHADICDAAAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSALDGDKKNSFRFHHISTDEVYGDLPHPDEVNNKEELPLFTETTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KALPIYGKGDQIRDWLYVEDHARALYTVVTEGKAGETYNIGGHNEKKNIDVVLTICDL
                     LDEIVPKEKSYREQITYVADRPGHDRRYAIDAEKISRELGWKPQETFESGIRKTVEWY
                     LANAKWVENVKSGAYQSWIEQNYEGRQ"
     gene            3383..4282
                     /gene="rmlD"
     CDS             3383..4282
                     /gene="rmlD"
                     /note="O048_03"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAQ00967.1"
                     /db_xref="GI:733166397"
                     /translation="MNILLFGKTGQVGWELQRALAPLGNLIALDVHSTDYCGDFSNPE
                     GVAETVKKIRPDVIVNAAAHTAVDKAESEPEFAQLLNATSVESIAKAANEVGAWVIHY
                     STDYVFPGNGDTPWLETDATAPLNVYGVTKLAGEKALQEHCAKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKEREELAVINDQFGAPTGAELLADCTAHAIRVALNKLEVAGLYHLVAS
                     GTTTWHDYAALVFEEARKAGIPLALNKLNAVPTSAYPTPARRPHNSRLNTEKFQQNFA
                     LVLPDWQVGVKRMLNELFTTTAI"
     gene            4340..5215
                     /gene="rmlA"
     CDS             4340..5215
                     /gene="rmlA"
                     /note="O048_04"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="BAQ00968.1"
                     /db_xref="GI:733166398"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTSQDTPRFQQLLGDGSQWGLNLQYKVQPTPDGLAQAFIIGEEFIGG
                     DDCALVLGDNIFYGHDLPKLMDVAVNKESGATVFAYHVNDPERYGVVEFDKNGTAISL
                     EEKPLQPKSNYAVTGLYFYDNDVVEMAKNLKPSARGELEITDINRIYMEQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDAEQVKALAEPL
                     KKNAYGQYLLKMIKG"
     gene            5223..5783
                     /gene="rmlC"
     CDS             5223..5783
                     /gene="rmlC"
                     /note="O048_05"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="BAQ00969.1"
                     /db_xref="GI:733166399"
                     /translation="MNVIKTDIPDVLIFEPKVFSDERGFFFESFNQKVFEEAVGRKIE
                     FVQDNHSKSSKGVLRGLHYQLEPYAQGKLVRCVVGEVFDVAVDIRKSSPTFGKWVGIN
                     LSAENKRQLWIPEGFAHGFITLSDNAEFLYKTTNFYSPKHEVCIRFDDEKIGIEWQRA
                     EYMRLSEKDSKGVSLDEYVHMVVDRL"
     CDS             5780..6694
                     /note="O048_06"
                     /gene="wffH"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ00970.1"
                     /db_xref="GI:733166400"
                     /translation="MNKVSILMPVYNVEKYIRAAITSILNQTYQNIELVIVDDASTDG
                     TSLIIDEIAKRNNNIIIVRNNVNSGITVALNKGLKYCSGDYIARADGDDIQDPLRIQK
                     QIDFLKENQEYGLVGCWIKNIDESGRQIASCKYPVSDLEVRQCVSYTSPVLHIWLAKK
                     DVYDKLNGYRNTNPAEDYDFILRCLDYGIRIGNVPYYGSMIRLRSGNTLTESSLKQRV
                     ISNYLCKKFKKGIINTIDIESELPKINEFNIITKIHSWSCFFLKKAIENKRTLKGAAY
                     LCLSLISPYTVQNIIKRQVFKRKYNKGY"
     CDS             6696..7739
                     /note="O048_07"
                     /gene="wekI"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ00971.1"
                     /db_xref="GI:733166401"
                     /translation="MIKIAIILPSLKNVGPNRVAHTLINRLSDKEGVYLKVFYIKKEL
                     GLNFTCDTEVLTLGNVRKLYTFDVLHSHMLRPDILVGLLPFYKGLKISTIHNIVTEDI
                     QYTHGSVISKIVSELWFRIWNRFDKIVVLSKVAKKYYTEHELKPKKLEVIYNGIDLCI
                     GSNISSEDKEIIKKFKGNSTLLGTLCLANHRKGIEQILYALPFLPNCKFIIIGDGPAR
                     EYLENLAISLNVRKRFFILGYRENAKDLLKYIDIYLMPSRSEGFSLALLEAVAAKKTV
                     VCSNIPIFKETFTERQVSFFDLDNTNSLIQAIKNSINNDINDAYIRLKQNYSSDSMAQ
                     SYHELYMTCKEVK"
     CDS             7736..8518
                     /note="O048_08"
                     /gene="wdaC"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ00972.1"
                     /db_xref="GI:733166402"
                     /translation="MRVFISVVSHGHGELIESLRCLEKLSEKFSVVLKDNKNESNLKE
                     YCKHNNIIYLSSDIPKGFGENNNIIFNYCISELKMQSDDIFIIMNPDVIVEENELIKL
                     KNKMICENIEFATINLYKDRDYKIYDPSIRNYPGILDFVSGYLGFSNKTIINKSSINS
                     NTTVAWAAGSFLALKSYIYKEVGGFDIRYFMYCEDIDICMRINSYGYKLVYIPTIKAI
                     HIARHNNRRFLSKHFYWHLRSALIYLSEKRKYVSKKNKYHHK"
     gene            8484..9707
                     /gene="wzx"
     CDS             8484..9707
                     /gene="wzx"
                     /note="O048_09"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAQ00973.1"
                     /db_xref="GI:733166403"
                     /translation="MSLKKISTTISKVIGGNALAQIIVILGTPLLTRIYQPSDFGIYS
                     TIMAVVLILGVIACGRYDQIMYNFDDKYSWYICFCNGLVIAICISLLCLITTGALFYF
                     FKFDISYLVIAPSIFTFAILQLYTSYFSLYSYYRTIIILNIIRTSSLVVLQLILFKFS
                     KNGLIVSFLLSQIICILFCLKLGRKLNRKFKFKVSFLKIREAGLSSVQSLASSFSSQL
                     PVLFISGQYGFYIVSLYGLAVRLTQVPIIFFTNAVRPYILGELNRNKRNYRLLSNIIW
                     RSSILLLSLSMIGIILINLFATDFFKIYAGEEWEGAGEIASALAWWLLVSFANVTSTS
                     YLTVIGRFRSLFIYDMFLLVFRVMAVCYSFYMKLSFIDFIYIYSIIGMLFNLGIIGYA
                     IKCSIRDAKNSDCYI"
     CDS             9917..10975
                     /note="O048_10"
                     /gene="wcdK"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ00974.1"
                     /db_xref="GI:733166404"
                     /translation="MKVIHIVHNYYGFSGASLQAKNLAKALKKHAPNIEQIFVTRCQN
                     RISKLSEDVQFSVMEISSSYKRFWQFFLLCKSIKPDVVHFHGADFGLLGICAIFKIPV
                     YWKSTLLDCDDFHTLINRGSLRSLKHWLLRFISINNTLSKQIYEINSKYIPITRLVTI
                     PNGVSAPDCMYGNEQIKEKIVLIISAIIPRKKIIEGIKFYKDNFENQGYKLLIIGPDN
                     ESLDGFEAGYVLNCKQFSSNNIHFLGKIEHQKINEIMCRSQFLIHLSEREGMPNVVLE
                     ALANGVYPIIGEMGGLAYEMINNGSCGFICNNKDKFDINKYMGVNITGIDMVNEKYSF
                     DVISEKTFNIYMKLIGEK"
     gene            10972..12093
                     /gene="wzy"
     CDS             10972..12093
                     /gene="wzy"
                     /note="O048_11"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAQ00975.1"
                     /db_xref="GI:733166405"
                     /translation="MKLENNNADKKISFIGLLWLISCGLYITQITAISPVYFIFILSM
                     ILVFLTNVSCRKWDVSFFTLISLIISLLSTFLFINSHFSLVINLCMVLLSPMLVDFYY
                     KGRSITKRNLLNVFLFYSFVFILDGFWRIQHPYLANVDKLEELGIGFQIYKVNSLMYA
                     DSNFVGLEAVFILSCFLYFFRDIKIVGLLRVRYFLVFCALFVGVVLTFSRAAIIAMIL
                     LFVLSVLMKNKRIKAFSYMLMPVLLIVLSWFVFKKFTDDISFESKFDLIRYSLEYIKN
                     NNVEVILLGVGLGNAVDVIGMGAHNLFLTFLIETGMIGLFLFLVLLCIMCIYLKEDAI
                     VIVLPFLIASMSLGTTAIPYFFTFTWLCILFKRKLFNVI"
     CDS             12112..13122
                     /note="O048_12"
                     /gene="gne"
                     /codon_start=1
                     /transl_table=11
                     /product="putative UDP-glucose 4-epimerase"
                     /protein_id="BAQ00976.1"
                     /db_xref="GI:733166406"
                     /translation="MNILVTGGLGYIGSHTLIRLIELKYNVIVVDNFSNSKASVIDRI
                     KALSGGEFVFYDYDICNAESLQEIFSKHDINKVIHFAGLKSVSESSRAPLTYYHNNVV
                     GTLNLLQLMCINGIKDIIFSSSATVYGLPDNMPLTEKCVTGGTTNPYGTSKHMVEQIL
                     MDLIQSDGDWNITILRYFNPIGAHPSGEIGEDPLGVPNNLVPYVTKVAIGDLPYLTIY
                     GDDYSTPDGTGIRDFIHVCDLAEGHIAALNNKKTNGLHIYNLGTGVGSSVLEIVNTFE
                     RVNNVSVPYRISKRRKGDVPECWADPSLIRAELSWSAKYNLEDMLKHAWLWQLKNPKG
                     YD"
     gene            13227..14633
                     /gene="gnd"
     CDS             13227..14633
                     /gene="gnd"
                     /note="O048_13"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ00977.1"
                     /db_xref="GI:733166407"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPFLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKIRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKDGVFHTEWLD"
     gene            14882..16048
                     /gene="ugd"
     CDS             14882..16048
                     /gene="ugd"
                     /note="O048_14"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ00978.1"
                     /db_xref="GI:733166408"
                     /translation="MKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVNMLNKKQSP
                     IVDKEIEEYLATKDLNFRATTDKYDAYKNADYVIIATPTDYDPKTNYFNTSSVEAVIR
                     DVTEINPNAVMIIKSTIPVGFTESIKERFGIENVIFSPEFLREGKALYDNLHPSRIVI
                     GEQSDRAERFAALLQEGAIKQDIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNSRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADSILARKPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGVPVIV
                     YEPAMKEVDFFRSRVVRDLDAFKQEADVIISNRMSADLADVADKVYTRDLFGND"
     CDS             16153..16662
                     /note="O048_15"
                     /codon_start=1
                     /transl_table=11
                     /gene="IS1"
                     /product="transposase of IS200c"
                     /protein_id="BAQ00979.1"
                     /db_xref="GI:733166409"
                     /translation="MRSGNCKCQTRNQKGVPMGNEKSLAHTRWNCKYHIVFAPKYRRQ
                     VFYREKRRAIGCILRKLCEWKSVRILEAECCADHIHMLVEIPPKMSVSGFMGYLKEKS
                     SLMLYEQFGDLKFKYRNREFWCRGYYVDTVGKNTAKIQDYIKHQLEEDKMGEQLSIPY
                     PGSPFTGRK"
     CDS             complement(16786..17790)
                     /note="O048_16"
                     /codon_start=1
                     /transl_table=11
                     /gene="IS2"
                     /product="putative nucleotide sugar epimerase"
                     /protein_id="BAQ00980.1"
                     /db_xref="GI:733166410"
                     /translation="MKFLVTGAAGFIGFYVSKQLLAAGHQVVGIDNLNDYYDVNLKQA
                     RLDLLKHDNFSFYKIDLADREIMAALFADERFDRVINLAAQAGVRYSLENPNAYADAN
                     LIGFLNILEGCRHNNVRHLLYASSSSVYGMNRKMPFSTDDSVDHPVSLYAATKKANEL
                     MAHTYSHLYGLPTTGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNFGKMKRDFT
                     YIDDIAEAIIRLQDVIPEKDPQWAVETGSPATSSAPYRVYNIGNSSPVELMDYINALE
                     EALGIEANKNMMPLQPGDVLETSADTKALYDVIGFKPETSVKEGVKNFVEWYRNFYKV
                     "
     gene            18159..19193
                     /gene="wzz"
     CDS             18159..19193
                     /gene="wzz"
                     /note="O048_17"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ00981.1"
                     /db_xref="GI:733166411"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLV
                     QLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGP
                     AVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQPLPLAVSYVGETP
                     EGAQKQLAKYIQQVDDQVNEELEKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQ
                     IQEALQYANQAQVTKPQVQQTEDVTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQT
                     RQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLG
                     RNALRNYNAK"
     gene            complement(19290..>19477)
                     /gene="hisI"
     CDS             complement(19290..>19477)
                     /gene="hisI"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="BAQ00982.1"
                     /db_xref="GI:733166412"
                     /translation="TKRIAQKVGEEGVETALAATVHDRFELTNEASDLMYHLLVLLQD
                     QDLDLTTVIENLRKRHQ"
BASE COUNT     5877 a   3433 c   4261 g   5906 t
ORIGIN
        1 acatcaccaa ttgtaagttc agcgacttac agggggacgc tattgaatgg aacgtggcga
       61 ttaacgacca tgatattttg atatctgacc atgtcatcga gcgcatcaac tgtactaacg
      121 gcaaaatcaa ctggggcatc ggcataggcc ttgcggggag tacttatgat aataactacc
      181 cggaagacca ggcagtgaaa aactttgtcg tggcgaatat cacgggatcg gattgtcggc
      241 agttgatcca tgttgaaaat ggtaaacatt ttgttattcg taatatcaaa gcccgcaata
      301 tcacgccgga tttcagtaag aaagcaggta ttgataacgc gacggtcgct atttacggtt
      361 gtgacaattt cgtgattgat aatattgaaa tgattaatag cgctgggatg ttaatcggct
      421 atggggtaat taaaggcaaa tatctctcga taccgcaaaa tttccgagtg aataatattc
      481 aaatggataa cacccatctt gcttataaat tgcgcggtat ccaaatctct gccgggaatg
      541 ctgtctcctt tgtggcgctg actaacattg agatgaagcg tgcgtcgctg gagttacaca
      601 acaaaccgca acatcttttt atgcgaaata tcaaggtgat gcaggaatcc tcagttggac
      661 cagcattgag catgaacttc gacatgcgca aagacgttcg cggcgtcttt atggcgaaaa
      721 aagaaacact gctgtcactt gcaaatgttc atgcggtgaa tgaaaaaggg caaagctccg
      781 tcgatatcga caggataaat caccatattg ttaatgtgga aaagattaac tttagattgc
      841 cggaacggag ggagtagatt tgcgaccatt cctggaaaaa tggagccata cttaggaaca
      901 atgctactgc aatccacaac gaagcggcgt aacatcacaa gtaattcagt aatcaattca
      961 gggtaattga tgctggcgaa aaaaatcgaa caagctataa ttcagcaacc attttacagg
     1021 tggatgaaat aatgacgaat ttaaaagcag ttattcctgt agcgggtctt gggatgcata
     1081 tgttgcctgc cactaaggcg attcccaaag agatgctacc gatcgtcgac aagccaatga
     1141 ttcagtacat tgttgacgag attgtggctg cagggatcaa agaaatcctc ctggtaactc
     1201 acgcgtccaa gaacgcggtc gaaaaccact tcgacacctc atatgaatta gaatctctcc
     1261 ttgagcagcg cgtgaagcgt caactgcttg cggaagtgca gtccatctgt ccaccgggcg
     1321 tgaccattat gaacgtgcgt cagggcgaac ctttaggttt aggccactcc attttgtgtg
     1381 cacgacccgc cattggtgac aacccatttg tcgtggtgct gccagacgtt gtgatcgacg
     1441 atgccagcgc cgacccgctg cgctacaacc ttgcagccat gattgcgcgc ttcaacgaaa
     1501 cgggacgcag ccaggtgctg gcaaaacgta tgccgggcga tctctctgaa tactccgtca
     1561 ttcagaccaa agaaccgctg gatcgcgaag gcaaagtcag ccgcattgtt gaatttatcg
     1621 aaaaaccgga tcagccgcag acgctggact cagacatcat ggccgttggt cgctatgtgc
     1681 tttctgcaga tatttggccg gaacttgaac gcactcagcc aggtgcatgg ggacgtatcc
     1741 aactgacaga tgccattgcc gaactggcga aaaaacagtc tgttgatgca atgctgatga
     1801 ctggtgacag ctacgactgc ggtaaaaaaa tgggttatat gcaggcgttt gtgaagtatg
     1861 gactacgcaa cctcaaagaa ggggcgaagt tccgtaaggg tattgagaag ctgttaagcg
     1921 aataatgaaa atctgaccga atgtaacggt tgataagaaa attataacgg cagtgaagat
     1981 tcgtggcgaa agtaatttgt tgcgaatatt cctgccgttg ttttatataa acaatcagaa
     2041 taacaacgag ttagcaatag gattttagtc aaagttttcc aggattttcc ttgtttccag
     2101 ggcggattgg taagacaatt agcgtttgaa tttttcgggt taagcgcgag tgggtaacgc
     2161 tcgtcacatc gtaggcatgc atgcagtgct ctggtagctg taaagccagg ggcggtagcg
     2221 tgcattaata cctctattaa tcaaactgag agccgcttat ttcacagcat gctctgaagt
     2281 aatatggaat aaattaagtg aaaatacttg ttactggtgg cgcaggattt attggttctg
     2341 ctgtagttcg tcacattata aataatactc aggatagtgt tgttaatgtc gataaattaa
     2401 cgtacgccgg aaacctggaa tcacttgctg atgtttctga ctctgaacgc tatgtttttg
     2461 aacatgcgga tatttgcgat gctgctgcaa tggcgcggat ttttgctcag catcagccgg
     2521 atgcagtgat gcacttggct gctgaaagcc atgtggatcg ttcaattaca ggccctgcgg
     2581 catttattga aaccaatatt gttggtactt atgtcctttt ggaagcggct cgcaattact
     2641 ggtctgctct tgatggcgac aagaaaaata gcttccgttt tcatcatatt tctactgacg
     2701 aagtttatgg cgatctgcct catcctgacg aagtaaataa taaagaagaa ttacccttat
     2761 ttactgagac aacagcttac gcaccaagta gcccatattc tgcttcgaaa gcatcaagcg
     2821 atcatttagt ccgcgcgtgg aaacgaacct atggtttacc gaccattgtg actaactgct
     2881 ctaacaatta tggtccttat catttcccgg aaaaattgat tccattggtt attctgaatg
     2941 ctctggaagg taaagcatta cctatttatg gtaaagggga tcaaattcgc gattggttgt
     3001 atgtcgagga tcatgctcga gcgttatata cagtcgttac tgaaggtaaa gcgggtgaaa
     3061 cttataacat tggtggacac aacgaaaaga aaaacatcga tgtagtgctc actatttgtg
     3121 atttgttgga tgagattgta ccgaaagaga aatcttaccg cgagcaaatt acttatgttg
     3181 ccgatcgccc gggacacgat cgccgttatg cgattgatgc agagaagatt agccgcgaat
     3241 tgggctggaa accgcaggaa acgtttgaga gtgggattcg taaaacggtg gaatggtacc
     3301 tggctaatgc aaaatgggtc gagaatgtga aaagtggtgc ctatcaatcg tggattgaac
     3361 agaactatga gggccgccag taatgaatat tctccttttc ggcaaaacag ggcaggtagg
     3421 ttgggaacta cagcgtgctc tggcaccttt gggtaatttg attgctcttg atgttcactc
     3481 cactgattat tgtggtgatt ttagtaatcc tgaaggtgtg gctgaaaccg tcaaaaaaat
     3541 tcgccctgat gttattgtta atgctgcggc tcacaccgca gtagataagg ctgagtcaga
     3601 acccgaattt gcacaattac tcaatgcgac tagcgttgaa tcaattgcaa aagcggctaa
     3661 tgaagttggg gcttgggtaa ttcattactc aactgactac gtattccctg gaaatggcga
     3721 cacgccatgg ctggagacgg atgcaaccgc accgctaaat gtttacggtg taaccaagtt
     3781 agctggagaa aaagcattac aagagcattg tgcgaagcac cttattttcc ggaccagctg
     3841 ggtctatgca ggtaaaggaa ataacttcgc caaaacgatg ttacgtctgg caaaagagcg
     3901 tgaagaatta gcggttatta acgatcagtt tggtgcacca acaggtgctg agctgctggc
     3961 tgattgtacg gcgcatgcca ttcgtgtggc attgaataag ctagaagtcg caggtttgta
     4021 ccatttggta gccagtggta ccacaacctg gcacgattat gctgcgcttg tttttgaaga
     4081 ggcgcgcaaa gcaggcattc cccttgcgct caacaagctc aacgcagtac caacatcagc
     4141 ctatcctaca ccagctcgtc gtccacataa ctctcgcctt aatacagaaa aatttcagca
     4201 gaactttgcg cttgtcttgc ctgactggca ggttggcgtg aaacgaatgc tcaacgaatt
     4261 gtttacgact acagcaattt aatagttttt gcatcttgtt cgtgatgatg gagcaagatg
     4321 aattaaaagg aatgatgaaa tgaaaacgcg taaaggtatt attttagcgg gtggttctgg
     4381 tacacgtctt tatcctgtga ctatggctgt cagtaaacag ctattaccta tttatgataa
     4441 gccgatgatc tattacccgc tctctacact gatgttggcg ggtattcgcg atattctgat
     4501 tattagtacg tcacaggata ctcctcgttt tcaacaactg ctgggtgacg gtagccagtg
     4561 ggggctaaat cttcagtaca aagtgcaacc gactccagat gggcttgcgc aggcgtttat
     4621 tatcggtgaa gagtttatcg gtggtgatga ttgtgctttg gttcttggtg ataatatctt
     4681 ctacggccac gatctgccga agttaatgga tgtcgctgtt aacaaagaaa gtggtgcaac
     4741 agtatttgct tatcacgtaa atgatcctga acgctacggt gtcgttgagt ttgataaaaa
     4801 cggtacggca attagtctgg aagaaaaacc gttacaacca aaaagtaatt atgcggtaac
     4861 tgggctttat ttttatgata acgacgttgt cgaaatggcg aaaaatctta agccttctgc
     4921 ccgtggtgaa ctggaaatta ccgatattaa ccgtatttat atggaacagg ggcgtttatc
     4981 cgttgccatg atggggcgtg gttatgcatg gcttgacacg gggacgcatc aaagtcttat
     5041 tgaagcaagc aacttcattg ccaccattga agagcgccag ggactaaagg tttcctgccc
     5101 ggaagaaatt gcttaccgta aagggtttat tgatgcagag caggtgaaag cattagctga
     5161 gccgctgaaa aaaaatgctt atggtcagta tctgctgaaa atgattaaag gttagtaata
     5221 aaatgaacgt aattaaaact gacattccag atgtgctaat ttttgaaccg aaagttttta
     5281 gcgatgagcg cggtttcttt tttgagagtt ttaaccagaa ggtttttgag gaagctgtcg
     5341 ggcggaagat cgagtttgtt caggacaacc attcgaagtc aagcaaaggt gttttacgcg
     5401 ggctacatta tcagctagaa ccttacgcac aaggaaaatt ggtgcgttgt gttgttggtg
     5461 aagtttttga tgtggcggtt gatatccgta aatcttcacc cacttttggt aaatgggtag
     5521 ggattaattt atctgctgaa aataaacggc aattgtggat cccggaaggg tttgcacatg
     5581 gattcataac gttgtcagat aatgcagaat ttctttataa aacaactaat ttttattctc
     5641 caaaacatga agtttgtatt cgatttgatg atgaaaaaat agggattgag tggcagcgtg
     5701 cagagtatat gagactctca gaaaaagatt caaaaggggt atctctcgat gaatacgtgc
     5761 atatggtggt tgatagatta tgaataaagt tagcatatta atgcctgttt ataatgtgga
     5821 aaaatatatt agggctgcga ttactagtat tttaaaccaa acatatcaga atatagaatt
     5881 agtgattgta gacgatgcgt ctactgatgg tacctcgctc attatagatg aaattgcgaa
     5941 aagaaataat aatataatta ttgttcgtaa taatgtaaac tcagggataa ctgtagcact
     6001 aaacaagggg cttaaatatt gtagcggtga ttatatagct agagctgatg gtgatgatat
     6061 acaagatcca ttacgaattc aaaagcaaat agattttcta aaggagaatc aagaatatgg
     6121 attggtcgga tgttggataa aaaacataga tgagtcaggc agacaaatag cttcatgtaa
     6181 atatccggtt tcagacttag aagtgagaca atgtgttagc tatacatctc ctgtacttca
     6241 tatatggtta gcaaagaaag atgtttacga taaacttaat ggatacagga atacaaatcc
     6301 agctgaagat tatgatttta ttttaagatg tttggattat ggtataagaa tagggaatgt
     6361 tccgtattat ggatcaatga tacgtttgcg ttcggggaat acactaactg aatcttctct
     6421 aaaacaaaga gttatatcaa actatctgtg caaaaaattt aaaaaaggca tcattaatac
     6481 aattgatatt gagtctgagt tacctaaaat aaatgaattt aacatcatca ctaaaataca
     6541 ttcttggtca tgtttctttt taaaaaaagc aatagagaat aaaagaacat taaaaggtgc
     6601 agcttattta tgtttgtcgc ttataagtcc ttatacagtt caaaatataa taaagcggca
     6661 ggtttttaaa agaaagtata acaagggtta ctaagttgat aaaaatagca ataatattac
     6721 catcattgaa aaacgttgga ccgaatagag ttgcacatac tcttattaat agattaagcg
     6781 ataaagaagg tgtgtacctt aaggttttct atataaaaaa agaattagga ttaaatttta
     6841 cttgtgatac agaagttttg actttaggta atgtgcgaaa attatacacc tttgatgttt
     6901 tgcattcaca tatgcttagg ccagatatct tggttgggtt acttccattt tataaaggac
     6961 ttaaaataag tacaatccat aatatagtaa cagaagatat acaatataca catgggagcg
     7021 tgatatctaa aattgtctct gaattatggt ttaggatttg gaatagattt gataagatag
     7081 tcgtgttatc aaaagtagca aaaaaatatt atacggaaca tgaactaaaa cctaagaaat
     7141 tagaggtgat atataatgga attgatctgt gtataggaag taatattagt tctgaagata
     7201 aggaaataat aaagaagttt aaaggaaaca gtactcttct gggaacactt tgcttagcaa
     7261 atcacaggaa aggtatagaa cagattctgt atgccttgcc attcttacca aattgtaaat
     7321 ttataattat tggtgatggg cctgcaagag aatatttaga gaatttagct ataagtctga
     7381 atgtgagaaa gcgatttttt attctgggct atagagaaaa cgctaaagat ttactaaagt
     7441 atatcgatat ttatttaatg ccaagtagat cggaaggatt tagtctcgca ttgcttgagg
     7501 ctgttgctgc aaaaaaaaca gtagtttgct caaatattcc aatatttaaa gaaaccttta
     7561 ctgaacgaca agtgtctttt tttgacctgg ataatacaaa ctcacttatt caagcgataa
     7621 agaattcaat aaataatgat ataaatgacg cgtatataag gctaaagcaa aattatagtt
     7681 cagattctat ggctcaatca tatcatgaat tatatatgac ttgtaaggaa gtaaaatgag
     7741 ggtttttata tctgttgtat cacatggaca cggggaatta attgagtcat taaggtgttt
     7801 agaaaaactt tcggaaaagt ttagtgttgt gcttaaagat aataaaaatg aatccaatct
     7861 taaagagtat tgcaagcata ataatataat ctatttaagt agcgatattc ctaaaggctt
     7921 tggtgagaat aataatatta tatttaatta ttgcatatct gaattgaaaa tgcagtcaga
     7981 tgatatattt ataataatga atccagatgt aattgttgaa gaaaatgaat tgataaaact
     8041 taaaaataag atgatatgtg aaaatataga gtttgctact ataaatcttt ataaagatag
     8101 agactataaa atatatgatc catcaatcag gaattatccg ggcatccttg actttgtaag
     8161 tggttatctt ggtttctcaa ataaaacaat aataaacaaa tcgtcaatta attcaaatac
     8221 taccgtagct tgggccgcag ggtcgttctt ggcattaaag tcatatatct ataaagaagt
     8281 aggtggtttt gatatccgat atttcatgta ttgtgaagat atagatatat gcatgaggat
     8341 aaattcttat ggctataagt tagtttacat accaactata aaagccatac atattgcgag
     8401 gcacaataat cggcgttttt tatcaaaaca tttttattgg catttgcgta gtgcacttat
     8461 atatttatcg gaaaagagaa agtatgtctc taaaaaaaat aagtaccacc ataagtaaag
     8521 taatcggtgg taatgcatta gcacaaatta ttgttatatt aggcaccccc ttacttacaa
     8581 gaatttatca accaagtgat tttggtatat attctactat catggcagtg gttttaatat
     8641 tgggagttat tgcgtgcggt agatatgatc agataatgta taatttcgat gacaaatatt
     8701 cgtggtacat atgtttttgt aatggacttg ttatcgcaat atgcatatcc ttattgtgtt
     8761 taattacgac tggagcatta ttttattttt ttaaatttga tataagttac cttgttattg
     8821 ctccatcaat atttaccttt gcgatattgc agttatatac gtcttacttt agtctgtatt
     8881 cttattacag aaccataata atattaaata tcattaggac ttcaagctta gttgtattac
     8941 aattaatttt gtttaagttt tctaaaaatg ggcttattgt gagctttcta ttatctcaaa
     9001 taatatgtat cctattttgc ttaaaactag gaagaaaact taatagaaaa tttaagttta
     9061 aagtgagttt tttgaagatc agagaagccg gtttgagctc tgttcagtct cttgctagtt
     9121 ctttttcttc acaattgcca gttcttttta tttctggaca atatggtttt tatattgtaa
     9181 gtctgtatgg cttggctgta agattaactc aggtaccaat tatttttttc acaaatgccg
     9241 ttagaccata tattctggga gagttaaata ggaataaaag aaattatcgt cttttatcaa
     9301 atataatatg gagaagctcg atcttattac tatctctaag tatgatcgga ataattctca
     9361 ttaatttatt tgcaactgat ttttttaaaa tttatgcagg tgaagaatgg gaaggcgctg
     9421 gtgaaatagc ttcagcttta gcatggtggc tcttggtatc ttttgctaat gttacttcaa
     9481 cttcatattt aactgttatt ggacgattca gatctttatt tatctatgat atgttcctat
     9541 tggtatttag agtaatggct gtatgctata gcttttatat gaagttatca tttatagatt
     9601 tcatatacat ttattctata attggtatgc ttttcaactt gggtattatc ggttatgcga
     9661 taaaatgtag cattcgagat gctaaaaata gcgattgtta tatttgagta cgcttgcttt
     9721 gtgtaaggtg aattcacttg aggtaaaggt gtattgaaga ccaaaaaact gacggtaata
     9781 aaatattatt aacgttattt caatggtttt accttttttg tgtgttgtgt gatagcaaaa
     9841 attttattat agacagcaca atagtaaata aatttaaaat gttttctatt aggttttcaa
     9901 agagaaaaat atataaatga aagtgatcca tatagtacat aattattatg gctttagcgg
     9961 cgcatctctt caagcaaaaa atttagcaaa ggctttaaaa aaacatgccc ccaatatcga
    10021 acaaattttt gtgactagat gccagaatcg tatttctaaa ttaagtgagg atgttcaatt
    10081 cagtgtaatg gaaatatctt catcatataa aagattttgg cagttctttc ttttgtgtaa
    10141 atctattaaa ccggatgttg ttcatttcca tggggctgat tttggtcttc ttggtatttg
    10201 tgctattttc aaaatacctg tctattggaa atcaacttta ttggattgtg atgatttcca
    10261 tacattgata aatcgtggtt ctttgaggtc tcttaagcac tggttgttga ggtttatttc
    10321 gataaacaat acgttatcga aacaaatata tgaaattaat agtaaataca ttcccatcac
    10381 taggttggtt actattccaa atggcgtcag tgcccctgat tgtatgtacg ggaatgaaca
    10441 gattaaggaa aaaatagttt taataatatc tgcaattata ccaagaaaaa aaataataga
    10501 aggaataaaa ttttataaag ataattttga aaaccaagga tataaacttt tgataattgg
    10561 ccccgataat gaaagtcttg atggttttga agcaggttat gtgctgaact gtaagcagtt
    10621 tagtagtaat aatatccatt ttttaggtaa aattgaacat caaaaaatta atgaaataat
    10681 gtgtcgttct caattcctaa tacatttatc ggagcgagaa ggtatgccaa atgttgtgtt
    10741 ggaggcactt gctaatggtg tctatccgat aattggggaa atgggagggc ttgcttatga
    10801 aatgataaat aacggttctt gtggatttat ttgcaataat aaagataagt ttgatataaa
    10861 taaatatatg ggtgttaata taactggaat agatatggtc aacgaaaaat attcgtttga
    10921 tgtgatttca gaaaagacat ttaatatata tatgaaactt attggtgaaa aatgaaactt
    10981 gaaaataata atgctgataa aaaaatctca tttatcggcc ttttatggtt gatatcttgt
    11041 ggtttatata taacccaaat aactgcgatt agtcctgttt attttatttt tattctttca
    11101 atgattttgg tttttcttac aaatgttagt tgcaggaaat gggatgtttc ttttttcaca
    11161 ctcataagtc ttattatatc actattgtca actttccttt ttataaactc gcatttttca
    11221 cttgtaatta atctgtgtat ggtgctgctt tctccaatgt tggtggattt ttattataag
    11281 ggacgaagca ttacaaaaag aaatttattg aatgttttct tgttttattc attcgttttc
    11341 attcttgatg gtttttggag aattcaacat ccgtatcttg caaatgttga taagttagaa
    11401 gaactgggta tcggctttca aatatataaa gtaaactcac ttatgtatgc cgattccaac
    11461 tttgttggtc tagaagctgt ttttatatta tcctgttttc tttatttctt cagagatatt
    11521 aaaattgttg gtttattgcg cgtaagatac tttcttgttt tttgtgcttt atttgttggg
    11581 gttgttttaa ctttctctag ggctgctatc atagcaatga tattgctttt tgtgctttct
    11641 gttctaatga aaaataagcg catcaaagct ttctcatata tgcttatgcc agtattactt
    11701 attgttcttt catggtttgt atttaaaaaa ttcacggatg atataagctt tgaaagtaaa
    11761 tttgatttaa ttaggtattc actcgaatac attaagaata ataatgttga ggtgatattg
    11821 ctgggggttg gtcttggaaa tgcagtcgat gttattggta tgggggcaca taatctgttt
    11881 ctgactttct taattgaaac tggcatgatt ggattatttt tatttttagt attattatgc
    11941 attatgtgca tttacctcaa agaggatgct attgtcatcg tgcttccatt tttgatagca
    12001 tcaatgtcac tcggaacaac tgcaattcct tactttttta cctttacttg gttatgtatt
    12061 ctttttaaaa gaaaattatt taatgtcatt tgacattgta aaggaaacaa catgaacata
    12121 ttagttactg gtggcttagg atatataggt tctcatactt taattcgatt gattgagtta
    12181 aaatataacg tcatagttgt tgataatttt tcaaactcta aagcaagtgt gattgacaga
    12241 ataaaagcgc tgagcggtgg agaatttgta ttttatgatt atgatatttg taatgctgaa
    12301 tctctgcaag aaattttttc taaacatgat attaataagg ttattcattt tgctggattg
    12361 aaatcagttt cagaatctag tagggcacct ttaacatatt atcacaacaa tgtagttgga
    12421 acgttaaact tattgcagtt aatgtgtata aatgggataa aggatattat atttagttct
    12481 tctgcgactg tatatggact gccagataat atgccattaa ctgaaaaatg tgtaactgga
    12541 ggaactacaa atccttacgg gaccagtaag catatggtcg aacaaatttt gatggattta
    12601 attcaatctg atggcgattg gaatataact attcttagat attttaaccc tattggtgcc
    12661 cacccttcag gagagattgg agaggatcct ctaggagttc ctaataatct agtaccttac
    12721 gtgactaaag tcgcaattgg ggatttgccg tatttgacca tttatggcga tgattatagt
    12781 acgcctgatg gaactggaat cagagatttt attcatgttt gcgatttagc tgaaggacat
    12841 atagctgcat tgaataataa aaaaacaaat ggtctacata tttataattt aggtacgggt
    12901 gttggttcat ctgtattaga gatagtaaat acatttgagc gagttaataa tgtctctgtt
    12961 ccttatcgta tctccaaacg acgaaagggt gatgtgcctg aatgctgggc cgatccatca
    13021 ttgattagag ctgaattaag ttggagcgca aaatataatc ttgaggacat gttgaagcat
    13081 gcttggcttt ggcaactcaa aaatccaaag ggttatgatt aatcgaggca acacttttat
    13141 tggttcatta tttatgataa taaaggtgta tgtttacatc attttaaata ccaccatcaa
    13201 agcggcaatc ctgacaggag taaacaatgt caaagcaaca gatcggcgtc gtcggtatgg
    13261 cagtgatggg gcgcaacctt gcgctcaaca tcgaaagccg tggttatacc gtctctattt
    13321 tcaaccgttc ccgtgaaaag acggaagaag tgattgccga aaatccaggc aagaaactgg
    13381 ttccttacta tacggtgaaa gagtttgttg aatctctgga aacgcctcgt cgcatcctgt
    13441 taatggtgaa agcaggtgca ggcacggatg ctgctattga ttccctcaag ccattcctcg
    13501 ataaaggtga catcatcatt gatggtggta ataccttctt ccaggacact attcgtcgta
    13561 accgtgagct ttctgcagaa ggctttaatt tcattggtac cggtgtttcc ggcggtgaag
    13621 aaggtgcgct gaaaggtcct tccattatgc ctggcggaca gaaagaagcc tatgaactgg
    13681 ttgcgccgat cctgactaaa atcgccgcag tggctgaaga cggtgagcca tgcgttacct
    13741 atattggtgc cgatggcgca ggtcactatg tgaagatggt tcacaacggt attgaatacg
    13801 gcgatatgca gctgattgct gaagcctatt ctctgcttaa aggtggcctg aatctttcta
    13861 acgaagaact ggcgcagacg tttaccgagt ggaataacgg tgaactgagc agttacctga
    13921 tcgacatcac caaagatatc ttcaccaaaa aagatgaaga cggtaactac ctggttgatg
    13981 tgattctgga tgaagcggct aacaaaggta ccggtaaatg gaccagccag agcgcgctgg
    14041 atctcggcga accgctgtcg ctgattaccg agtctgtgtt tgcacgttat atctcttctc
    14101 tgaaagatca gcgtgttgcc gcatctaaag ttctctctgg cccgcaagca cagccagcag
    14161 gcgacaaggc tgagttcatc gaaaaaattc gccgtgcgct gtatctgggc aaaatcgttt
    14221 cttacgctca gggcttctct cagctgcgtg ctgcgtctga agaatacaac tgggatctga
    14281 actacggcga aatcgcgaag attttccgtg ctggctgcat catccgtgcg cagttcctgc
    14341 agaaaatcac cgatgcatat gccgaaaatc cgcagatcgc taacctgctg ctggctccgt
    14401 acttcaagca aattgccgat gactaccagc aggcgctgcg tgatgtcgtt gcttatgcag
    14461 tacagaacgg tatcccggtt ccgaccttcg ccgctgcggt tgcctattac gatagctacc
    14521 gtgccgctgt tcttcctgcg aacctgatcc aggcacagcg tgactatttc ggtgcgcata
    14581 cttataagcg cattgataaa gacggtgtgt tccataccga atggctggat taatctgatt
    14641 taaatcaatt aaccaacaca aggcccggag aaaccctccg ggctttttta ttatacaaag
    14701 cggcaggtta tggccttttt ttataattta tagttaaaaa cgcgatataa tacagcgccg
    14761 cacagcagga tcgctgcctt gacagttcat ctacatcagc gttaaaaatc ccgcagtaga
    14821 tgaagttgtg gtggtggatt aatgaccact ctaaatgttt aaccggaaga agtcagagct
    14881 aatgaaaata acaatttcag gaacaggtta tgttggtctt tcaaatggta ttctgattgc
    14941 gcaaaatcac gaagtggttg cactggatat cgttcaggcc aaagtgaaca tgcttaacaa
    15001 gaagcagtca ccgattgttg ataaggagat tgaagagtat ctggcgacta aagatctcaa
    15061 tttccgcgct acgacagata agtatgacgc gtataaaaat gccgattacg ttattattgc
    15121 cacacctacc gattatgatc cgaaaacaaa ttattttaat acctcaagcg tggaagcggt
    15181 cattcgcgat gtgacagaaa ttaatcccaa tgctgtaatg attataaaat caactatccc
    15241 tgttggtttt acagagtcca ttaaagaacg gtttggtatt gaaaatgtga tcttttcgcc
    15301 tgagtttttg cgtgaaggta aagcacttta tgataactta cacccatcac gcattgtgat
    15361 tggcgagcaa tccgaccgcg cagaacgttt tgcagcgtta ttacaggaag gcgctattaa
    15421 gcaagacata ccaacattgt ttactgactc aaccgaggct gaggcgatta aactttttgc
    15481 caacacctat ctggcgatgc gtgtagcgta tttcaatgaa cttgatagtt atgctgaaag
    15541 cctggggctt aattcacgcc agattattga gggcgtatgc cttgacccgc gtatcggtaa
    15601 tcactacaac aacccgtcat tcggttatgg tggttattgt ctgccgaaag atactaagca
    15661 gttactggca aattaccagt ctgtgccgaa taacctgatc tcggcaattg ttgacgccaa
    15721 ccgcacgcgc aaagatttta ttgccgattc tatccttgca cgtaaaccga aagttgttgg
    15781 cgtctatcgt ttgattatga agagtggttc agacaatttc cgtgcttcct cgattcaggg
    15841 tattatgaag cgaatcaagg ctaaaggtgt gccagtaatc gtttatgagc cagcgatgaa
    15901 agaggtcgat tttttccgtt cgcgcgtggt acgtgatctg gatgcgttca aacaagaagc
    15961 tgatgttatt atttctaacc gtatgtctgc cgatctggct gatgtagcag ataaggttta
    16021 tacgcgcgac ttgtttggca atgattaatt attttgtttc atactaagaa aacccccagc
    16081 taggctgggg gttccggaaa gctttcagct ttgagccagt tattataacc ccttttgatt
    16141 tgttaaaaca ccttgcggtc tggcaactgc aagtgtcaaa caagaaatca aaagggggtc
    16201 ccaatgggga acgaaaagag cttagcgcac acccgatgga actgtaaata tcacatagtt
    16261 tttgcgccaa aataccgaag acaagtgttc tacagagaga agcgtagagc aataggctgt
    16321 attttgagaa agctgtgtga gtggaaaagc gtacggattc ttgaagctga atgctgtgca
    16381 gatcatatcc atatgcttgt ggagatcccg cccaaaatga gcgtatccgg ctttatggga
    16441 tatctgaaag agaaaagcag tctgatgctt tacgagcagt ttggtgattt gaaattcaaa
    16501 tacaggaaca gggagttctg gtgcagaggg tactacgtcg atacggtggg taagaacacg
    16561 gcgaagatac aggattacat aaagcaccag cttgaagagg ataaaatggg agagcagtta
    16621 tcgattccct atccgggcag cccgtttacg ggccgtaagt aacgaagttg gatgcaaatg
    16681 tcagatcgtg tgcgcctgtt agggcgcggc tggtaagaga gccttatagg cgcatttgaa
    16741 aaacctccgg ctatgccgga ggatatttat tatggtttta taaaatcaaa ctttatagaa
    16801 gttacgatac cattctacaa agttctttac cccctcttta actgacgttt caggtttgaa
    16861 tcctattacg tcatacagtg cttttgtatc agcactggtt tccagtacat caccgggttg
    16921 gagaggcatc atattcttgt tggcttcaat acccagagcc tcttctaagg cattgatata
    16981 atccattaac tccacaggcg aactattacc aatgttatag acacgatatg gtgctgaact
    17041 tgttgctggc gagcctgttt ctacagccca ctgtggatct ttttctggaa taacatcctg
    17101 taagcgaata atagcttcgg caatatcatc aatataagta aagtcacgct tcattttgcc
    17161 gaagttgtaa acatcaatgc ttttaccttc cagcatggct ttagtgaatt taaataatgc
    17221 catatctgga cgtccccatg gaccataaac cgtaaagaaa cgcagccctg tggtcggtaa
    17281 gccatacaaa tgagaatacg tatgggccat gagttcattc gcctttttag ttgctgcata
    17341 cagcgaaaca ggatgatcta cagagtcatc tgtagagaaa ggcatcttgc ggttcatgcc
    17401 ataaacagaa ctggaggaag cgtaaagtag atgccgaaca ttattatggc gacatccttc
    17461 cagtatgttc aggaatccaa tcaggtttgc atctgcatat gcattgggat tttcaaggga
    17521 gtaacgtaca ccggcttgcg cagcgaggtt tattacgcga tcgaaccgct cgtctgcaaa
    17581 cagtgccgcc attatctcgc gatcggccag gtcaatttta taaaaactga aattgtcgtg
    17641 cttgagtaaa tcaagtcgtg cttgtttgag gttgacatcg taataatcat ttaagttgtc
    17701 aatgcctaca acctgatgac cagctgcaag aagctgttta cttacataga aaccgataaa
    17761 gccagcagct cccgtaacca gaaatttcat ttataatcct cgctcaggct agaatatagc
    17821 caatcttcat ctggcataac tgaaagttaa atcataccgt tagacaagaa aaaaagataa
    17881 tcggtatcag ttctaaacct ggctgttttt tctggtaacg tgctcatttt acaatcaaag
    17941 ctgttccaag ctgactatta gaccaccttc aaacaacaag ccgacgtcat tatttccaac
    18001 cgtatggcag aagagcttaa ggatgtggca gacaaagtct acacccgcga tctttttggc
    18061 agcgactaac atcatgttat cagggcgatt ttcgccctga ttctcttatg ttccctttgt
    18121 aataattcat tatttttatc atttatccta tagcattcat ggcgattatc gctaaactat
    18181 ggcgacttaa aattatttcg tccgttaggg taatgatgag agtagaaaat aataatgttt
    18241 ctgggcaaaa ccatgacccg gaacagattg atttgattga tttactggtg cagttgtggc
    18301 gtggcaagat gacaattatc atctctgtca ttgtggctat tgccctggct atagggtatc
    18361 tggccgttgc caaagaaaag tggacttcca cagctatcgt tactcaacct gatgtggggc
    18421 aaatcgctgg ttataccaac gcgatgaatg tgatttacgg tccggctgta ccgaaagtct
    18481 ccgacattca ggcttcactt atcggacgtt acagcactgc attctcagca ttagcggaaa
    18541 cgctggataa ccaggaagaa gcagagaagc tgaccattga gcctaccgtt aaaaaccagc
    18601 cgttaccact ggcggtgtct tatgttggtg aaacacctga aggtgcgcag aagcagctgg
    18661 cgaagtatat ccagcaagtt gacgaccagg taaacgaaga actggaaaaa gacctgaaag
    18721 acaacatcgc gctgcgtatg aaaaacttgc aggattcgct gaagacccag gaagtggttg
    18781 cgcaggagca gaaagatctg cgtatccgtc agattcagga agcgttgcag tatgcgaatc
    18841 aggcgcaggt gacaaagcca caggttcagc agactgaaga tgtgacgcaa gatacgttgt
    18901 tccttttggg gagcgaagct ctggagtcga tgattaagca tgaggcgaca cgtccgttag
    18961 tgttctcacc aaactactat cagacacgtc aaaacctgct ggatatcgaa aacttaaagg
    19021 ttgatgatct tgatattcat gcttaccgtt atgtgatgaa accgacgtta cctattcgtc
    19081 gcgatagccc gaaaaaggca attaccttga ttctggcggt gctgctgggc ggcatggttg
    19141 gcgcggggat tgtcttgggg cgtaacgctc tgcgtaatta caacgcgaag taatcttttc
    19201 ggttttaaag aaaaagggca gggtggtgac accttgcccg ttttttttgc cggatgctac
    19261 aacaatatcg catccgctta ccccgcaact cactgatgcc gtttacgcag gttctcaatc
    19321 accgtcgtta agtccagatc ctgatcctgc aacagcacca gcaggtgata catcaaatca
    19381 gacgcctcgt tggtgagctc aaagcggtca tgtactgtcg ctgccagtgc ggtttccacg
    19441 ccttcttcgc ccactttctg cgcaatgcgt ttggtgc
//
