LOCUS       AB811596               19014 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli DNA, O-antigen biosynthetic locus, strain: U1-41.
ACCESSION   AB811596
VERSION     AB811596.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 19014)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..19014
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="U1-41"
                     /db_xref="taxon:562"
                     /note="serogroup:O5"
     gene            <1..902
                     /gene="wcaM"
     CDS             <1..902
                     /gene="wcaM"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="BAQ00558.1"
                     /translation="AILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDSDILISD
                     HLIERINCTNGKINWGIGIGLAGSTYDNNYPENLAVKNFVVANITGSDCRQLIHVENG
                     KHFVIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKG
                     KYLSIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQ
                     HLFMRNIKVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNERGQSSVD
                     IDRVNHHIVNVEKINFRLPERRE"
     gene            1060..2055
                     /gene="gnu"
     CDS             1060..2055
                     /gene="gnu"
                     /note="O005_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4-epimerase"
                     /protein_id="BAQ00559.1"
                     /translation="MNDNVLLIGASGFVGTRLLETAIADFNIKNLDKQQSHFYPEITQ
                     IGDVRDQQALDQALAGFDTVVLLAAEHRDDVSPTSLYYDVNVQGTRNVLAAMERNGVK
                     NIIFTSSVAVYGLNKHNPDENHPHDPFNHYGKSKWQAEEVLREWYNKAPTERSLTIIR
                     PTVIFGERNRGNVYNLLKQIAGGKFMMVGAGTNYKSMAYVGNIVEFIKYKLKNVAAGY
                     EVYNYVDKPDLNMNQLVAEVEQSLNKKIPSMHLPYPLGMLGGYCFDILSKITGKKYAV
                     SSVRVKKFCATTQFDATKVHSSGFVAPYTLSQGLDRTLQYEFVHAKKDDITFVSE"
     gene            2298..3191
                     /gene="galF"
     CDS             2298..3191
                     /gene="galF"
                     /note="O005_02"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ00560.1"
                     /translation="MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNV
                     RQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRS
                     QVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLS
                     ADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFRKGIEKLLSE"
     CDS             3315..3527
                     /note="O005_03"
                     /codon_start=1
                     /transl_table=11
                     /gene="IS1"
                     /product="transposase orfA of IS1X4"
                     /protein_id="BAQ00561.1"
                     /translation="MYDGVFEVLQWLLFLSAVPPVQLLKAWCVTVKVLPDISAISALT
                     AVKHGSYSSLTPLLNPVRIRKSLIWP"
     CDS             3538..4041
                     /note="O005_04"
                     /codon_start=1
                     /transl_table=11
                     /gene="IS2"
                     /product="transposase orfB of IS1X4"
                     /protein_id="BAQ00562.1"
                     /translation="MSRQCTHYGRWPQHGFTSLKKLRPQSVTSRIQPGSDVIVCAEMD
                     EQWGYVGAKSRQRWLFYAYDRIRRTVVAHVFGERTLATLERLLGLLSAFEVVVWMTDG
                     WPLYESRLKGELHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVIGHY
                     LNIKHYQ"
     gene            4341..5426
                     /gene="rmlB"
     CDS             4341..5426
                     /gene="rmlB"
                     /note="O005_05"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6 dehydratase"
                     /protein_id="BAQ00563.1"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLA
                     DVSDSERYIFEHADICDAAAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSALDSDKKNSFRFHHISTDEVYGDLPYPDEVNNKEELPLFTETTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KALPIYGKGDQIRDWLYVEDHARALYIVVTEGKAGETYNIGGHNEKKNIDVVLTICDL
                     LDEIVPKEKSYREQITYVADRPGHDRRYAIDAEKISRELGWKPQETFESGIRKTVEWY
                     LAKMQWVENVKTGNYQSWIEQNYMERN"
     gene            5426..6289
                     /gene="rmlA"
     CDS             5426..6289
                     /gene="rmlA"
                     /note="RmlA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="BAQ00564.1"
                     /translation="MKGIILAGGSGTRLYPITMGVSKQLLPIYDKPMVYYPLSVLMLA
                     GIKDILIITTPEDQAGFIRLLGDGSQFGIEIKYATQSSPDGLAQAFIIGESFIGNDSV
                     CLVLGDNIFFGQGFTPKLKLACERTQGATVFGYQVMDPERFGVVEFDSQFKALSIEEK
                     PIKPKSNWAVTGLYFYDNDVIDIAKYIEPSSRGELEITTVNEVYLKNDSLNVELLGRG
                     FAWLDTGTHDSLIEAGSFVETVQKRQGMMVACLEEIAWRNGWLSKENLYERGQLLSKN
                     HYGQYLLKLVG"
     CDS             6293..6688
                     /note="FdtA"
                     /codon_start=1
                     /transl_table=11
                     /gene="fdtA"
                     /product="putative dTDP-6-deoxy-3,4-keto-hexulose
                     isomerase"
                     /protein_id="BAQ00565.1"
                     /translation="MNIQLIPLQIHGDDRGALVSLERDKNIDFEIRRVYYIFDTKKGV
                     VRGYHAHKNLKQLVIAVKGSCRFTLDDGSERVSVFLDNPAQGLLVNSLIWREMSDFSE
                     DCVLMVLASNEYDESDYIRDYDAFKLAAK"
     CDS             6685..7152
                     /note="QdtC"
                     /codon_start=1
                     /transl_table=11
                     /gene="qdtC"
                     /product="putative acetyltransferase"
                     /protein_id="BAQ00566.1"
                     /translation="MMFIHKLSDVQSTSIGEGTNIWQFVVVLRKAIIGKDCNICANCF
                     IENDVVIGNSVTIKSGVFIWDGVRVHDNVFIGPCVAFTNDKYPRSKNYDAQFYETIIG
                     ENSSIGANSTILPGVKIGRNCMIGAGSVVTKDVPDNALVLGNPARIVKFLEAE"
     CDS             7149..8252
                     /note="QdtB"
                     /codon_start=1
                     /transl_table=11
                     /gene="qdtB"
                     /product="putative aminotransferase"
                     /protein_id="BAQ00567.1"
                     /translation="MIDFLNLQKSNARYNNELIEAAVRVIESGWYISGSELNAFENNF
                     AKYCKVKHAIGVANGLDALTLTLKAWQELGKLKRNDEVLVPANTYIASILAISEAGLK
                     PVLVEPNEFSYNLSVDNIRAKITANTRVILPVHLYGLISPMDEIMNFARENNLLVLED
                     SAQSHGASINGKKAGSWGDAAGFSFYPGKNLGALGDAGAVTTNDTDLADTVRYLRNYG
                     SKIKYKHEFKGVNSRLDEIQAAFLNVKLNYLDDDIRIRRNIANRYLNEIKNELIVLPT
                     ISSEENHVWHLFVIRIKDRDSLQHYLTKHNIQTVIHYPTPPHRQLAYKEFKDLCFPLS
                     EELHREVISIPMDPTLTEEQVSYVINVLNKFNC"
     gene            8255..9511
                     /gene="wzx"
     CDS             8255..9511
                     /gene="wzx"
                     /note="Wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAQ00568.1"
                     /translation="MNLIKVSFYNGISVIIKMLTMLGLNKVLAIYVGPSGYAIIGQYQ
                     SFVQTLATFSAGSISNGITKYTAQNVNVEKELIGVWKTAGTVSIVSSLFVSIMILIFF
                     KDINSVFFSNKIDNDLSYWLAASFVFMMLNSYLMAILNGMKQIKAYVLLNISSSILVL
                     VMTGLFAVTMGLKGALIALTINQSANFIITFSYFIKQKWFKIRFLAGNLNKTILKGLS
                     RFAFMALFSSLAVPLTQMFLRNFIGTNISWEISGYWEAINRISAINIMLATTTLTLYY
                     LPKLSETHEKKKYKHELINISKLLVPVTAFGCICVFYLKFYIINILFTPSFVNMSPLF
                     GWQMVGDFFKVFSWIFSFALLTKEKWKIFIACEILSAIVLAASTIIIVCFMSWHYLSA
                     AYAATYFIYLIFTSTFFYQSIYKKAS"
     gene            9512..10828
                     /gene="wzy"
     CDS             9512..10828
                     /gene="wzy"
                     /note="Wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAQ00569.1"
                     /translation="MEFTLNFIIIILSFIPGYYLGVFRFKRLNYYCVLYWSMLLFCVI
                     GSFIINSGVMDDSFFVGPIANNAEVKNLGLFITTISFFIFFLSAFIVEVFCSLYSGQS
                     SVMIHWNNYYSRPIIMSSYKVVLTLCILSCALVFYYIVSIYPAPLSMALQGASADEIA
                     VRRLEVTKNYSGIGYFKTLAGIIPIILSYYCFISYLKFKKHFLLFIFITCISTLTLAI
                     NGEKAPLVFYFLGLLVSYSSVREITKKIYVFSAFLIFSLILIMYVVLFQFDNSDYLLY
                     ILVERLFIAQEAAVFYAADYFSTHNLLGLSSMDTIFNKILSITPTARASEIFMYQYLP
                     GMAENGGWNVNGFFAHETFSNFGYIGIVLGSMYGGIVNGLLCIYFRAREKTVLTMSFY
                     SFYVVSVTTVLSSFNSMLFNTQLILVFIIFLILSVLDRRRKHAVPE"
     CDS             10812..11690
                     /note="WbuM"
                     /codon_start=1
                     /transl_table=11
                     /gene="wbuM"
                     /product="glycosyltransferase"
                     /protein_id="BAQ00570.1"
                     /translation="MQYQSDRVSIIIISYNHEQFIEKAIESVLFQTYKDIELIIVDNN
                     SSDNTREILNQYKDVYNIKVIYLENNTGITGGINEGLKYVSGEFVSFFASDDIMVSNR
                     IELQVNALRKEPEAIACFGNMLRINSDGSINKRGLLPMVGFKWWALNDILTNRICLYS
                     PTQLYRADVFTSDSINFPTEVRVEDIWLYFKLLNTGYKFITIPYLLTMYRVHDNNTHT
                     RYKMMMQEKIKILNDYKNEAFYKKALNFIYLEHFSNFGSTSKKDALRILPKVILNIKS
                     KYLYIGLIRLLFDWRK"
     CDS             11690..12358
                     /note="WbuN"
                     /codon_start=1
                     /transl_table=11
                     /gene="wbuN"
                     /product="putative hydrolase"
                     /protein_id="BAQ00571.1"
                     /translation="MFKHVYVDLCDTLIKGNTTFMFLDSFFSHHQNNRYWLYRKLSTS
                     FLMRVIFKLFFSAKIDLNRRIAIHFLNGYSIDFLREHVKWMLVNGIFIENKELVEVIQ
                     CAKSEHIPVTIVSASLDFIVEVVASHYSINYYSSKLAYKDGYCQGRIILDLLFNKNKI
                     FDDVEQNKSAYCFISDNIQDIQILKSCSYGFGVPNLKNEKAFIVNNIKLINYDRLINL
                     IKSE"
     CDS             12355..13149
                     /note="WbuO"
                     /codon_start=1
                     /transl_table=11
                     /gene="wbuO"
                     /product="hypothetical protein"
                     /protein_id="BAQ00572.1"
                     /translation="MIVKDYSIFYLPFWYSKQTRFRTIPRFFSWIIIYVIPVSLSFLF
                     VSPEFNYFNLFKSLLAILLVYNLYEIGYIYNDTETIKKEISPTLRLESHQLQFYENNK
                     NNIYSFRFLVALLITFALSFYDRVFIFLLASWAIIPAYALYNSVRSRLNIPLHFVLVT
                     LRYCSPVLLFTGGGGAYICFFMILLFPLINTLERCTESRFKFDYFKDLFLTNRKNGRY
                     VYYLILLIAGLTCCYIFGEYTFYVFSCYAFYYMAFRLLSAQVNLNE"
     CDS             13142..13969
                     /note="WbwC"
                     /codon_start=1
                     /transl_table=11
                     /gene="wbwC"
                     /product="glycosyltransferase"
                     /protein_id="BAQ00573.1"
                     /translation="MNDSSRSFSVLMSLYYKEDPVYLDSCFASLANQLLLPTEIVCVF
                     DGPLNAALESVVFKWSEKLNITIVRLPVNVGLGNALNNGLAHCSFDIVARMDSDDICL
                     PERFQKQIPLFFSDKDLILLGSNIDEFEVCENTIKSVRKVPLSEAQIRECCKIKNPFN
                     HMTVVFRKNEILSLGGYQHHFLMEDYNLWLRVIAKGYKVCNIDSSLVKARVGNGMVGR
                     RKGIEYIKSEWKLFMLKKKLGFQSVFSGICIFLMRSVPRLLPKTVLSMLYSISRTKN"
     gene            14146..15552
                     /gene="gnd"
     CDS             14146..15552
                     /gene="gnd"
                     /note="Gnd"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ00574.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKDFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKEQRVAASKVLSGPQAQPSGDKGEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            15801..16967
                     /gene="ugd"
     CDS             15801..16967
                     /gene="ugd"
                     /note="O005_17"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ00575.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNSRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPHVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELRDVADKVYTRDLFGSD"
     gene            17077..18090
                     /gene="wzz"
     CDS             17077..18090
                     /gene="wzz"
                     /note="O005_18"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ00576.1"
                     /translation="MRTWKFPSVRVMMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKM
                     TIIISVIVAIALAIGYLAVAKEKWTSTAIITQPDVGQIAGYNNAMNVIYGQAAPKVSD
                     LQETLIGRFSSAFSALAETLDNQEEPEKLTIEPSVKNQQLPLTVSYVGQTAEGAQMKL
                     AQYIQQVDDKVNQELEKDLKDNIALGRKNLQDSLRTQEVVAQEQKDLRIRQIQEALQY
                     ANQAQVTKPQVQQTEDVTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQTRQNLLDI
                     ENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALRNY
                     NAK"
     gene            complement(18187..18798)
                     /gene="hisI"
     CDS             complement(18187..18798)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ00577.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPQALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVNITPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ"
BASE COUNT     5503 a   3529 c   4144 g   5838 t
ORIGIN
        1 acgccatctt acgccaggga tttcataacc agataatcgg tgccaacatc accaactgta
       61 agttcagcga cttacagggc gacgctattg aatggaacgt ggcgattaac gacagtgata
      121 ttttgatatc cgaccatctc attgagcgca ttaactgtac caacggcaaa atcaactggg
      181 gcatcggcat aggccttgcg ggaagtacct acgataataa ttatccggaa aacctggcag
      241 tgaaaaactt tgtcgtggcg aatatcacgg gatcggattg tcggcaactg atccatgttg
      301 aaaatggtaa acattttgtt atccgtaata tcaaagctcg taatatcacg ccggatttca
      361 gtaagaaagc aggtattgat aacgccacag ttgctattta tggttgtgac aactttgtga
      421 ttgataatat tgaaatgatt aatagcgccg ggatgttaat cggctatggg gtaattaaag
      481 gcaaatatct ctcgataccg caaaatttcc gagtgaataa tattcaactg gataataccc
      541 accttgctta caaattgcgc ggtatccaaa tctccgccgg gaatgctgtc tcctttgtgg
      601 cactgactaa cattgagatg aagcgtgcct cgctggagct tcacaataaa ccgcaacatc
      661 tttttatgcg aaatatcaaa gtgatgcagg aatcctctgt tggaccagca ttgagcatga
      721 acttcgacat gcgcaaagac gttcgcggcg tctttatggc gaaaaaagaa accctgctat
      781 ctcttgcaaa tgttcatgcg gtgaatgaaa gagggcaaag ctccgtcgat atcgacaggg
      841 ttaatcacca tattgttaat gtggaaaaga ttaactttag attgccggaa cggagggagt
      901 agatttgcga ccattcataa acttactgga tataatgttc taaaagatta taatcctcac
      961 actaactgtt aaagctgggg ctgggcagca ttgactactc agggaaggta ctcatcttta
     1021 tcttgtgttt cttacgtaac aaccagacta aagtgattta tgaacgataa cgttttgctc
     1081 ataggggctt ccggattcgt aggaacccga ctacttgaaa cggcaattgc tgactttaat
     1141 atcaagaacc tggacaaaca gcagagccac ttttatccag aaatcacaca gattggcgat
     1201 gttcgtgatc aacaggcact cgaccaggcg ttagccggtt ttgacactgt tgtactactg
     1261 gcagcggaac accgcgatga cgtcagccct acttctctct attatgatgt caacgttcag
     1321 ggtacccgca atgtgctggc ggccatggaa agaaatggcg ttaaaaatat catctttacc
     1381 agttccgttg ctgtttatgg tttgaacaaa cataaccctg acgaaaacca tccacacgac
     1441 cctttcaacc actacggcaa aagtaagtgg caggcagagg aagtgctgcg tgaatggtat
     1501 aacaaagcac caacagaacg ttcattaacc atcatccgtc ctaccgttat cttcggtgaa
     1561 cgcaaccgcg gtaacgtcta taacttgctg aaacagatcg ctggcggcaa gtttatgatg
     1621 gtgggcgcag ggactaacta taagtccatg gcttatgttg gaaacattgt tgagtttatc
     1681 aagtacaaac tgaagaatgt tgccgcaggt tatgaggttt ataattacgt tgataagcca
     1741 gatctgaaca tgaaccagtt ggttgctgaa gttgaacaaa gtctgaacaa aaagatccct
     1801 tctatgcact tgccttaccc actaggaatg ttgggtggat attgctttga tatcctgagc
     1861 aaaattacgg gcaaaaaata cgctgtcagc tctgtgcgcg tgaaaaaatt ctgcgcaaca
     1921 acacagtttg acgcaacgaa agtgcattct tcaggttttg tggcaccgta tacgctgtcg
     1981 caaggtctgg atcgaactct gcagtatgaa ttcgtccatg ccaaaaaaga cgacataacg
     2041 tttgtttctg agtaatgcag acgagtcaga gaaaaaagga ccaggttgga ctacgattat
     2101 tcggaaagag gtactgatta aattatcagt atgtggattt ccgagtaatc cgagtaaccc
     2161 agatgctgat ggtgtgtagt gttatcgtaa ggtttaatca aagttatgcg gaactaagct
     2221 ttggtatata gccataccgt ttggctaacc tatgacaata atttacgcac tatcagccac
     2281 ttagaggtag gaaaataatg acgaatttaa aagcagttat accggtagcg ggtcttggga
     2341 tgcatatgtt gcctgccact aaggcgattc ctaaagagat gctaccgatc gtcgacaagc
     2401 caatgattca gtacattgtt gacgagattg tggctgcagg gatcaaagaa atcctcctgg
     2461 taactcatgc gtccaagaac gcggtcgaaa accacttcga cacctcttat gaattagaat
     2521 ctctccttga acagcgcgtg aagcgtcaac tactggcgga agtacaatct atctgtccgc
     2581 cgggcgtgac cattatgaac gtgcgtcagg gtgaaccttt aggtttaggc cactccattt
     2641 tgtgtgcgcg acctgccatt ggtgacaacc catttgtcgt ggtactgcca gacgtagtga
     2701 tcgacgacgc cagcgccgac ccgctgcgct acaaccttgc tgccatgatt gcgcgcttca
     2761 atgaaacggg ccgtagccag gtgctggcaa aacgtatgcc gggtgacctc tctgaatact
     2821 ccgttattca gaccaaagag ccgctggatc gtgaaggtaa agtcagccgc attgttgaat
     2881 tcatcgaaaa gccagatcag ccgcagacgc tggactcaga catcatggcc gttggtcgct
     2941 atgtgctttc tgccgatatt tggccggaac ttgaacgtac tcagcctggt gcatggggac
     3001 gtattcagct gactgatgcc attgccgagc tggcgaaaaa acagtccgtt gatgccatgc
     3061 tgatgaccgg cgacagctac gactgcggta aaaaaatggg ttatatgcag gcgtttgtga
     3121 agtatggact acgcaacctg aaagaagggg cgaagttccg taaaggtatt gagaagctgt
     3181 taagcgaata atgaaaatct gactggatgt aacggttgat aggaaaatta taacggcagt
     3241 gaagattcgt ggcaaaagta atttgttgcg aatattcctg ccgttgttgg taatggtgcc
     3301 aacttactga tttagtgtat gatggtgttt ttgaggtgct ccagtggctt ctgtttctat
     3361 cagctgtccc tcctgttcag ctactgaagg cgtggtgcgt aacggtaaaa gtactgccgg
     3421 acatcagcgc tatctctgct ctcactgccg taaaacatgg cagctacagt tcacttacac
     3481 cgcttctcaa cccggtacgc atcagaaaat cattgatatg gccatgaatg gcgtcggatg
     3541 tcgcgccagt gcacgcatta tgggcgttgg cctcaacacg gttttacgtc acttaaaaaa
     3601 ctcaggccgc agtcggtaac ctcgcgcata caaccgggca gtgatgtgat tgtctgcgct
     3661 gaaatggacg aacagtgggg ctacgtcggt gctaaatcac gccagcgctg gttgttttac
     3721 gcgtatgaca ggatacggag gacggttgtg gcgcacgtat tcggtgaacg cacgctggcc
     3781 acgctggagc gtcttctggg cctgctgtcg gcctttgagg tcgtggtatg gatgacggat
     3841 ggctggccgc tttatgaatc acgcctgaag ggagaactgc acgttatcag caagcgatat
     3901 acgcagcgca ttgagcggca taacctgaat ctgaggcagc atctggcaag gctgggcagg
     3961 aagtcactgt cgttctcaaa atcggtggag ctgcatgaca aagtcatcgg gcattatctg
     4021 aacataaaac actatcagta agttggagtc attaccgccg ttgttttata taaacaatca
     4081 gaataacaac gagttagcaa taggatttta gtcaaagttt tccaggattt tccttgtttc
     4141 cagagcggat tggtaagaca attaacgttt gaatttttcg ggtttagcgc gggtgggtaa
     4201 cgcccgtcac atcgtaggca tgcatgcagt gctctggtag ctgtaaagcc aggggcggta
     4261 gcgtgcatta atacctctat taatcaaact gagagccgct tatttcacag catgctctga
     4321 agtaatatgg aataaattaa gtgaaaatac ttgttactgg tggcgcagga tttattggtt
     4381 ctgctgtagt tcgtcacatt ataaataata cgcaggatag tgttgttaat gtcgataaat
     4441 taacgtacgc cggaaacctg gaatcacttg ctgatgtttc tgattctgaa cgctatattt
     4501 ttgaacatgc ggatatttgc gatgctgctg caatggcacg gatttttgct cagcatcagc
     4561 cggatgcagt gatgcacctg gctgctgaaa gccatgttga ccgttcaatt acaggtcctg
     4621 cggcatttat tgaaaccaat attgttggta cttatgtcct tttagaagcc gctcgcaatt
     4681 actggtctgc tcttgatagc gacaagaaaa atagtttccg ttttcatcat atttctactg
     4741 acgaagtcta tggtgattta ccttatcctg acgaagtaaa taataaagaa gaattaccct
     4801 tatttactga gacaacagct tacgcaccaa gcagccctta ttccgcatca aaagcatcca
     4861 gcgatcattt agtccgcgcg tggaaacgta cctatggttt accgaccatt gtgactaact
     4921 gctctaacaa ttatggtcct tatcatttcc cggaaaaatt gattccattg gttattctga
     4981 atgctctgga aggtaaagca ttacctattt atggtaaagg ggatcaaatt cgcgattggt
     5041 tgtatgtcga ggatcatgct cgagcgttat atatagttgt tactgaaggt aaagcaggcg
     5101 aaacctataa tattggcgga cacaacgaaa agaaaaacat cgatgtagtg cttactattt
     5161 gtgatttgct ggatgagatt gtaccgaaag agaaatctta tcgtgagcaa attacttatg
     5221 ttgccgaccg cccgggacat gatcgccgtt atgcgattga tgctgagaag attagccgcg
     5281 aattgggttg gaaaccacag gaaacgtttg agagcgggat tcggaagaca gtggaatggt
     5341 atctggcaaa aatgcagtgg gtggaaaacg tgaaaaccgg taattatcag tcttggattg
     5401 aacagaacta catggagcgt aactaatgaa gggtataatt ttagctggtg gctcaggtac
     5461 taggttatat ccaattacaa tgggtgtttc aaagcagtta ctcccgattt atgataagcc
     5521 gatggtttat tatccacttt cagtactgat gctggcaggt atcaaagata ttcttataat
     5581 taccacacca gaagatcagg ctggctttat ccgtttgctc ggggatggca gccaatttgg
     5641 tatagaaatc aaatatgcaa ctcaatcgag tccggatgga ttagcgcagg catttatcat
     5701 cggcgaaagt tttattggca atgattctgt ttgtcttgta ttaggtgata atattttctt
     5761 tggtcaagga ttcactccca aacttaaact tgcctgtgaa cgcacccaag gagcgactgt
     5821 atttggatat caggtaatgg atcctgaaag atttggtgtt gtcgagtttg atagccagtt
     5881 taaagcatta agcatcgaag aaaaaccaat aaaaccaaag tcaaattggg ctgttactgg
     5941 tttatatttt tatgacaacg atgtaataga tattgctaaa tatattgagc cttcttcacg
     6001 aggtgaactt gaaattacta ctgtgaatga agtttatttg aaaaatgatt cgttaaatgt
     6061 ggagttactt ggacgaggtt ttgcgtggct tgacacaggg acacacgata gtttaattga
     6121 agcaggcagt ttcgttgaga cagttcaaaa gagacaagga atgatggttg cttgtctgga
     6181 agaaatcgcc tggagaaatg gttggctctc aaaagaaaat ctttacgaaa gaggccaact
     6241 actgagtaaa aatcattacg ggcagtattt attaaaatta gtagggtgat atatgaatat
     6301 ccaacttatc ccattacaga ttcatggtga tgatagaggg gcccttgttt ctttagaaag
     6361 agataagaat atagacttcg aaattagacg tgtatattac atatttgata caaaaaaagg
     6421 ggtcgtcaga ggctatcatg cgcacaaaaa tttgaaacag ctagttatcg ctgttaaagg
     6481 atcgtgtcgt tttactttag atgatggaag cgaaagagta agtgtgtttt tagataatcc
     6541 tgctcaagga ttgcttgtta attctttaat ttggcgagag atgtcagatt tctctgaaga
     6601 ttgcgtctta atggttttag ctagcaatga atatgacgaa tctgattaca tcagggacta
     6661 tgatgcgttt aaattggcgg caaaatgatg tttatacaca aactaagtga cgttcagtca
     6721 acatctatcg gagaaggtac aaatatttgg caatttgtag tcgtccttag aaaagcaata
     6781 attggtaagg attgtaatat ttgtgctaat tgttttattg aaaatgatgt tgtcattgga
     6841 aattctgtaa ctataaaatc aggggttttt atctgggatg gagttagagt tcatgataat
     6901 gtgtttattg gtccttgcgt tgcatttact aatgataaat atccgcgttc taaaaattat
     6961 gatgcacaat tttatgaaac tataattggt gaaaattcat caataggggc aaattcgacc
     7021 attctgcctg gagtaaagat tgggcgcaat tgtatgattg gggcaggctc tgttgtaacg
     7081 aaagatgtgc ctgataatgc tttggttttg ggtaatccag caaggatcgt gaaatttttg
     7141 gaggcagaat gattgatttt cttaacttac agaaatccaa tgcgcgttat aataatgaat
     7201 taattgaagc tgcagtaaga gttattgaaa gtggatggta tatctcaggc tcagaactaa
     7261 atgcatttga gaataatttt gcgaagtact gtaaagttaa gcatgccata ggtgttgcta
     7321 atggacttga tgctctgacg ttgactctta aagcatggca agagctaggt aaattaaagc
     7381 ggaatgatga agtgcttgtg cctgcaaata cctacatagc ttcaattcta gccatcagtg
     7441 aggcaggttt aaagcctgtt ttagttgaac caaatgagtt cagctataat ttgtcagttg
     7501 ataatatcag agctaaaatc acagccaata cgcgagttat actccctgtt catctttatg
     7561 gcttgatttc tcctatggac gaaattatga attttgccag agaaaacaat ctattggtat
     7621 tggaagatag cgctcaatcg catggagctt caatcaatgg taaaaaagca ggaagttggg
     7681 gggatgcagc cgggtttagc ttttatcctg gcaagaatct aggtgcacta ggtgatgcgg
     7741 gagctgtaac gactaatgat acagacttag cagatacggt acgttatttg aggaattatg
     7801 gctcaaaaat aaaatacaaa catgagttta aaggtgtaaa tagtcgattg gatgaaattc
     7861 aggcagcttt cctaaatgta aaacttaatt atttagatga tgatattcgt attagacgta
     7921 atattgcaaa tcgatattta aatgaaataa aaaatgagtt aatcgtactt cctactattt
     7981 ccagtgaaga gaatcatgta tggcatcttt ttgtcatcag gataaaggat agggattcgc
     8041 tgcagcatta tcttacaaaa cataatattc aaacagtcat tcattatcct acaccacctc
     8101 atcgacaact ggcatataaa gaattcaaag acttgtgttt ccctcttagc gaagagttgc
     8161 accgtgaagt aatttcaatt ccaatggatc ccacacttac agaagagcaa gttagctatg
     8221 tcattaatgt actgaataaa tttaactgct aatcatgaat ttaattaaag tcagttttta
     8281 taatggtatt tctgtaataa ttaaaatgct gactatgcta ggacttaata aagtcctagc
     8341 tatttatgtc ggtcctagtg gttatgccat aataggtcag tatcagagtt ttgttcaaac
     8401 actcgctaca ttttcagcag gctcaatatc aaatggtatt acaaagtata cagctcaaaa
     8461 tgtaaatgtg gaaaaagaat taataggtgt ttggaaaact gctgggacag tcagtattgt
     8521 ttccagtttg tttgtttcaa tcatgatttt gatctttttc aaagatatca attctgtttt
     8581 ttttagtaac aaaattgata atgatctttc atactggctc gctgcctcat ttgtttttat
     8641 gatgttgaat agttatttaa tggctattct aaatggaatg aagcaaataa aagcatatgt
     8701 attgcttaat atatccagta gcatattagt gttagtgatg actggccttt ttgcggttac
     8761 catgggtctg aaaggtgctc tcatagcatt aacaatcaat cagtcagcaa attttataat
     8821 aaccttctca tattttatta agcaaaaatg gttcaagatt cgttttttag cggggaattt
     8881 aaataaaact attctcaaag ggcttagtcg atttgctttt atggctttgt tctcatcttt
     8941 agctgttcct ttaactcaga tgtttcttag gaatttcata ggtacaaata tttcttggga
     9001 gatatcaggt tattgggaag ccattaatcg gataagcgca ataaatatta tgttagcaac
     9061 cactacacta accctatatt atttgcccaa gctatctgaa acacatgaga aaaagaaata
     9121 taagcacgaa ttaatcaata tatccaaatt gttagtgcca gtcacagctt ttggttgtat
     9181 ttgtgttttt tatttaaagt tttatatcat aaatatactt tttactcctt catttgttaa
     9241 catgtcgccg ctgtttggct ggcaaatggt tggagatttt ttcaaggtat ttagctggat
     9301 tttttctttt gcactcttga cgaaagaaaa atggaagata tttatagcat gtgaaatttt
     9361 atcagcgatt gtccttgcag catcaacaat cataattgtt tgttttatgt catggcatta
     9421 tctgtctgca gcatatgcgg caacgtactt tatatatctg atatttacat caactttctt
     9481 ctatcagtcc atatataaaa aggcatctta gatggagttt actttaaatt ttattataat
     9541 aatattgagt tttattcctg ggtattactt gggtgtgttt cgttttaaaa ggctcaacta
     9601 ttattgcgtt ctttactggt ccatgctgct attttgtgtt attggatcat ttataataaa
     9661 ttcaggtgtc atggatgatt cgttttttgt aggaccaatt gcaaataatg ctgaggtaaa
     9721 aaaccttggc ttatttatta ctactatttc tttctttata ttctttctgt ctgcttttat
     9781 tgttgaagtt ttttgctcat tatactcagg gcaatcttcc gtaatgatac actggaataa
     9841 ttattactcg cgtcctataa ttatgagtag ttacaaggta gtattaacac tctgtatatt
     9901 atcatgcgca ttggtttttt attacatagt atcaatttat cctgcgccat tgtctatggc
     9961 tttacaggga gcttctgcgg atgaaatagc tgtccgacga ttagaagtga caaagaatta
    10021 ttcaggaatt gggtatttca aaacattagc aggtattata cctataattc tttcatatta
    10081 ttgttttata tcatatttaa aatttaaaaa acattttcta ctttttattt ttattacttg
    10141 tatttcaact ttaacattgg ctataaacgg ggaaaaagca cctttggttt tttatttttt
    10201 agggctttta gtttcatatt catctgtgag ggaaattact aaaaagattt atgtgttttc
    10261 cgcgttttta atattctcct tgatactgat aatgtatgtt gttctattcc agtttgataa
    10321 ttctgactat cttctttata ttcttgtcga aaggttgttt atagcccaag aggccgcagt
    10381 attttatgcg gcagattact tttctacaca taacttgctg ggtttatcta gcatggatac
    10441 tatttttaac aaaatactta gtattactcc aacagcaagg gcttcagaga tattcatgta
    10501 ccagtatttg ccaggtatgg cggagaatgg tggttggaat gtaaatggtt tttttgcaca
    10561 tgagactttc tctaatttcg gttacattgg gattgtgctt ggcagtatgt acggtggaat
    10621 agtaaatggt ttgttatgca tctactttag agcaagagaa aaaactgtgt taacaatgag
    10681 tttttatagt ttttacgttg tgtccgtaac aactgtacta agtagtttta attcaatgct
    10741 gtttaataca caactgattt tagtttttat tatttttttg atattatcag ttcttgacag
    10801 gagaagaaaa catgcagtac cagagtgata gggtctctat cattataata tcttataacc
    10861 atgaacaatt tatagaaaaa gcaatcgaaa gtgtattatt tcagacttat aaggatatag
    10921 agcttattat cgtcgataat aactcttcgg ataatactcg cgagatatta aaccaatata
    10981 aagatgtcta taacataaaa gtaatttatc ttgaaaacaa tacgggtatt acaggtggga
    11041 ttaatgaagg gttaaaatat gttagtgggg agtttgtaag tttctttgct agtgatgaca
    11101 ttatggtatc gaatagaatt gaactacaag ttaatgcttt aagaaaagaa ccagaggcca
    11161 ttgcttgctt tggtaatatg ctaagaatca acagtgatgg ctcaattaat aaacgaggtt
    11221 tgctaccaat ggtcggtttt aagtggtggg cactcaacga tatattgaca aacaggatat
    11281 gcttatactc tccaacgcaa ttgtatagag ctgatgtttt tacaagtgat tcaataaact
    11341 tcccaacaga agtcagggtt gaagatatct ggctatattt taaacttctc aacacaggtt
    11401 ataagtttat tactattcct tatcttctga ctatgtatcg agttcatgat aataacactc
    11461 atacgcgtta taaaatgatg atgcaagaga aaataaaaat cttaaatgat tataaaaatg
    11521 aagcctttta taaaaaagca ctcaatttta tctatcttga acatttctct aactttggtt
    11581 cgacttccaa aaaagatgcg ttaagaattc tacctaaagt tatattaaat attaagtcta
    11641 aatatttata catcggtctc atcaggctac tttttgattg gagaaagtaa tgtttaagca
    11701 tgtatacgtt gatttgtgtg atactttaat aaaaggcaac acaacgttca tgttcttgga
    11761 ttcctttttt agccatcacc aaaataatcg ctattggctt tacagaaaac tcagcacttc
    11821 atttttaatg agggtcatat ttaagttgtt cttttcagct aaaatagatc taaatcgaag
    11881 aattgcgatt cactttttaa atgggtacag catagatttt cttagagaac atgtaaaatg
    11941 gatgctagtc aatggtattt tcatagagaa taaggaactt gttgaagtta tacaatgtgc
    12001 taaaagtgaa catattccgg taacaattgt ttcggcttcc ttagatttca tagttgaggt
    12061 tgtagcatcc cattattcta ttaattatta cagtagcaaa cttgcatata aagatggata
    12121 ctgtcagggg cgtatcatcc ttgatcttct ttttaataag aataaaattt ttgatgatgt
    12181 agagcaaaac aaaagtgctt actgtttcat cagtgataat atccaagata ttcaaatatt
    12241 aaaatcttgt agctatggtt ttggtgttcc aaacctgaag aatgaaaaag cttttattgt
    12301 aaataatata aaacttatca actatgatag acttattaac ctgattaaga gtgagtgatt
    12361 gtgaaagact atagtatctt ttatcttcca ttctggtatt ctaagcaaac taggtttcga
    12421 acaattccaa gatttttttc atggattata atttatgtga ttcctgtctc tttgtctttt
    12481 ttatttgtgt ctccagaatt taattatttt aatttattta aatcacttct ggctatctta
    12541 ttagtctata atctatatga gattggatat atatataatg ataccgaaac aataaaaaaa
    12601 gaaatttcac caacactaag gcttgaatcc catcaattgc aattttatga aaataataag
    12661 aataatattt attcttttcg ttttttagtt gcattattaa taacctttgc gttatccttt
    12721 tatgataggg tattcatctt tttgctggct agttgggcta taataccagc atatgcatta
    12781 tataactcag tcagaagtag attaaatata ccattgcatt ttgtattggt cactttaaga
    12841 tactgttcgc cagtattatt gtttacgggg ggaggagggg cctatatttg tttttttatg
    12901 attttattat tcccccttat aaatacactt gaaagatgta ccgagagtag atttaaattt
    12961 gattatttta aagacttgtt tcttaccaat agaaaaaatg ggcgatacgt ctattatctt
    13021 attttgctca ttgcgggact tacttgttgt tatatttttg gtgaatatac attctatgtg
    13081 ttttcgtgtt atgcatttta ctatatggcc tttaggttat tatctgcgca ggtgaatctt
    13141 aatgaatgat agttcaagat catttagtgt attaatgtct ttatactaca aagaagatcc
    13201 agtctacctt gactcatgtt ttgcaagtct tgccaatcaa ttattacttc cgacagaaat
    13261 tgtttgtgtt tttgatggtc cacttaatgc tgcattagaa agtgttgtat ttaaatggtc
    13321 tgaaaaattg aatatcacta ttgtcaggct accggtaaat gttgggttag gtaatgcttt
    13381 aaataatggt cttgctcatt gctcatttga tatcgttgcg agaatggatt cagatgacat
    13441 ttgcctccct gaacgttttc aaaaacaaat acctcttttt tttagtgata aagaccttat
    13501 attgctaggt tctaacattg atgagtttga agtatgtgaa aatactatta aatcagtcag
    13561 gaaagttcca ttatccgagg ctcaaattcg tgagtgttgt aaaataaaga acccattcaa
    13621 tcatatgact gtggttttta gaaaaaatga aattttatcg cttggtggtt atcaacatca
    13681 tttccttatg gaggattata acctttggct tagagttatt gctaaaggat ataaagtatg
    13741 taatattgat agctcattag ttaaagctcg agtgggcaat gggatggtgg ggagaagaaa
    13801 gggaattgaa tatataaaaa gcgaatggaa gctttttatg ctcaagaaaa aacttggatt
    13861 tcagtctgtc ttttccggaa tatgcatttt cttgatgcgt tctgttcctc gcttactccc
    13921 taaaacagtg ctctcaatgc tttatagtat ttcaaggact aagaattaaa catttcggtt
    13981 attatccgta aacagtatct ctgagtaaat gaacgaaact gatgtttagc cgtatttgtt
    14041 cgttatctta aatgacgacg ctaccaagct aaacactatt gagttaatat caatagcaca
    14101 gtaaagccgc ttattagccg cggtaacccc tgacaggagt aaacaatgtc aaagcaacag
    14161 atcggcgtcg tcggtatggc agtgatgggg cgcaacctag cgctcaacat cgaaagccgt
    14221 ggttataccg tctctatttt caaccgttcc cgtgagaaga cggaagaagt gattgccgaa
    14281 aatccaggca agaaactggt tccttactat acggtgaaag attttgttga atctctggaa
    14341 acgcctcgtc gcatcctgtt aatggtgaaa gcaggtgcag gcacggatgc tgctattgat
    14401 tccctcaagc catacctcga taaaggtgac atcattattg atggtggtaa taccttcttc
    14461 caggatacta ttcgtcgtaa ccgtgagctt tctgcagaag gttttaactt cattggtacc
    14521 ggtgtttccg gcggtgaaga aggcgcgttg aaaggtcctt ccattatgcc tggtgggcag
    14581 aaagaagcct atgaacttgt tgcgccgatc ctgaccaaaa tcgccgccgt tgctgaagat
    14641 ggcgaaccgt gcgttaccta tattggtgcc gatggcgcgg gtcactatgt gaagatggtt
    14701 cacaacggta ttgaatacgg tgatatgcaa ctgattgctg aagcctattc tctcctgaaa
    14761 ggcggcctga atctttctaa cgaagaactg gcacagacct ttaccgagtg gaataacggt
    14821 gaactgagca gctacctgat cgacatcacc aaagacatct tcactaaaaa agatgaagac
    14881 ggtaactacc tggttgatgt gatcctggat gaagcggcta acaaaggtac cggtaaatgg
    14941 accagccaga gcgcgctgga tctcggcgaa ccgctgtcgc tgattaccga gtctgtgttt
    15001 gcacgttata tctcttctct gaaagagcag cgtgttgccg catctaaagt tctctctggc
    15061 ccgcaagcgc agccatctgg cgacaaaggt gagttcatcg agaaagttcg tcgtgcgctg
    15121 tatctgggta aaatcgtttc ttacgctcag ggtttctctc agctgcgcgc agcgtctgaa
    15181 gagtacaact gggatctgaa ctacggcgaa atcgcgaaga ttttccgtgc tggctgcatc
    15241 atccgtgcgc agttcctgca gaaaatcacc gatgcatatg ccgaaaatcc gcagatcgct
    15301 aacctgctgc tggccccgta cttcaagcaa attgccgatg actaccagca ggcgctgcgc
    15361 gatgtcgttg cttatgcagt acagaacggt atcccggttc cgaccttcgc cgctgcggtt
    15421 gcctattacg atagctaccg tgccgctgtt ctgcctgcga acctgatcca ggcacagcgt
    15481 gactatttcg gtgcacatac ttataagcgc attgataaag aaggtgtgtt ccatactgaa
    15541 tggctggatt aatctgattt aaccaacaat aaaattcagg cccggcgtat attgcaccgg
    15601 gctttttttt gccatttatc ttatagacta aatttcactg cttaatatta acttaataaa
    15661 tatcagctat tcttataaag aaaatctgaa ttgttttccg ttgcgttgac catctgacaa
    15721 cgtagcgtta aaacttttag ctcttatcag gatgctaaaa acatcatgat tcacagttaa
    15781 gttaattctg agagcatgaa atgaaaatca ccatttccgg taccggctat gtaggcttgt
    15841 caaacgggct tctaatcgca caaaatcatg aggttgtggc attagatatt ttaccgtcac
    15901 gcgttgctat gctgaatgat cggatatctc caattgttga taaggaaatt cagcagtttt
    15961 tgcaatcaga taaaatacac tttaatgcca cattagataa aaatgaagcc taccgggatg
    16021 ctgattatgt catcatcgcc actccaaccg actatgatcc taaaactaat tatttcaata
    16081 catccagtgt agaatcagta attaaagacg tagttgagat aaatccttat gcggttatgg
    16141 tcatcaaatc aacggttccc gttggtttta ccgcagcgat gcataagaaa tatcgtactg
    16201 aaaatattat tttctctccg gaatttctcc gcgaaggtaa agccctttac gataatctcc
    16261 atccttcacg tattgtcatc ggtgagcgtt cagaacgcgc agaacgtttt gctgctctgt
    16321 tacaggaagg cgctattaag caaaatatcc cgaccctgtt taccgactca accgaagcag
    16381 aagcgattaa actgtttgca aacacctacc tggcgatgcg cgtggcgtac tttaacgaac
    16441 tggatagcta cgcagaaagt ttaggtctga attcccgtca aataatcgaa ggcgtttgtc
    16501 tcgacccacg tattggcaac cattacaaca atccgtcgtt tggttatggt ggttattgtt
    16561 tgccgaaaga taccaagcag ttactggcga actatcagtc tgtgccgaat aacctgatct
    16621 cggcaattgt cgatgcaaac cgcacgcgta aagattttat tgccgatgcc attttgtcac
    16681 gcaaaccgca tgtggtaggt atttatcgcc tgattatgaa gagcggttca gataacttcc
    16741 gtgcgtcttc tattcagggg attatgaagc gtatcaaggc gaaaggtgtt gaagtaatca
    16801 tctacgagcc agtgatgaaa gaagactcat tcttcaactc tcgcctggaa cgtgatctcg
    16861 ccaccttcaa acaacaagcc gacgtcatta tctccaaccg tatggcagaa gagcttaggg
    16921 atgtggcaga taaggtctac acccgcgatc tctttggcag cgactaacat cttgttatca
    16981 gggctattta cgccctgatt gtcttttgtt acttacgcaa caattcatta tttttatcac
    17041 ttatcctata gcattcacga ggattatcgc taaactatgc ggacttggaa atttccgtca
    17101 gttagggtaa tgatgagagt agaaaataat aatgtttctg ggcaaaacca tgacccggaa
    17161 cagattgatt tgattgattt actagtgcag ttgtggcgtg gcaagatgac aatcatcatt
    17221 tccgtcattg tggctattgc cctggctatt ggttatttgg cagtagcgaa ggagaaatgg
    17281 acgtcaacag caattatcac tcagcccgac gtggggcaaa ttgctggcta taacaatgcc
    17341 atgaatgtta tctatggtca ggctgcaccg aaagtatcgg atttgcagga gacgttgatt
    17401 ggtcgcttca gttctgcctt ctctgcatta gcagaaacgc tggataatca ggaagaacca
    17461 gaaaaactta ccatcgaacc ttctgttaag aaccagcaat taccattgac tgtttcttat
    17521 gttgggcaaa ctgcagaggg agcacaaatg aagttggccc aatacattca gcaagttgat
    17581 gataaagtga accaagagct agaaaaggat ctcaaggaca acattgctct gggacggaaa
    17641 aacttgcagg actctttaag aacccaggaa gtagtcgcgc aggagcagaa agatctgcgt
    17701 atccgtcaga ttcaggaagc gttgcagtat gcgaatcagg cgcaggtgac aaagccacag
    17761 gttcagcaga ctgaagatgt gacgcaagat acgttgttcc ttttgggtag cgaagcgctg
    17821 gagtcgatga ttaagcatga agcgacccgt ccgttggtgt tctcgccaaa ctactatcag
    17881 actcgtcaaa acctgctgga tatcgaaaac ttaaaggttg atgatcttga tattcatgct
    17941 taccgttatg tgatgaaacc gacgttacct attcgtcgcg atagcccgaa aaaggcaatt
    18001 accttgattc tggcggtgct gctgggcggc atggttggcg cggggattgt cttggggcgt
    18061 aacgctctgc gtaattacaa cgcgaagtaa tcttttcggt tttaaggaaa aagggcaggg
    18121 tggtgacacc ttgcccgttt ttttttgccg gatgcgacaa caacatcgca tccgatcacc
    18181 cgcaactcac tgatgccgtt tacgcagatt ttcaattacc gtcgttaaat ccagatcctg
    18241 atcctgcaac agcaccagca ggtgatacat caagtcagat gcctcgttgg tcagctcaaa
    18301 gcggtcatgt accgttgctg ccagtgcggt ttccacgcct tcttcaccca ctttctgcgc
    18361 aatgcgcttg gtgccgctgg catacagttt ggcggtgtag gaggtttccg ggtcggcaga
    18421 tttgcgttcg gcgagcagtt gttccagttg atacaggaac agccactggt gagcggtgtc
    18481 gccgaagcag ctgctggtgc ctttgtggca ggtcgggccg atgggattcg ccagcaccag
    18541 taacgtgtcg ttgtcgcagt ccggcgtaat atttactacg ttgaggaaat tgcccgacgt
    18601 ttcgcctttg gtccacagtc gctgtttagt gcgcgagaag aaggtgactt tgccgctttc
    18661 gatggttttg tccagagctt gcgggttcat atagcccagc attagcactt cgccagatac
    18721 cgcgtgttgc acaatcaccg gcatcagtcc gtcggttttt tcccagtcca gttcgcgacg
    18781 ttgttgttct gttaacatat cctgatctcc acgccctgtg ttgccaggta cgcttttaat
    18841 tcaccaatat tgattatttg tttgtggaat acggaagctg ccagcgcgcc gtcaacgtcg
    18901 gcatcacgga aggcttccag gaagtgttcc atggtgcccg cgccaccgga ggcaatcagc
    18961 gggacgtggc aaacttcacg cacttttttc agctgctcga ggtcgtaacc gtta
//
