LOCUS       AF461121               27730 bp    DNA     linear   BCT 02-MAY-2002
DEFINITION  Escherichia coli serotype O55:H7 O-antigen gene cluster, complete
            sequence.
ACCESSION   AF461121
VERSION     AF461121.1  GI:18266395
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 27730)
  AUTHORS   Wang,L., Huskic,S., Cisterne,A., Rothemund,D. and Reeves,P.R.
  TITLE     The O-antigen gene cluster of Escherichia coli O55:H7 and
            identification of a new UDP-GlcNAc C4 epimerase gene
  JOURNAL   J. Bacteriol. 184 (10), 2620-2625 (2002)
   PUBMED   11976290
REFERENCE   2  (bases 1 to 27730)
  AUTHORS   Wang,L., Huskic,S., Cisterne,A., Rothemund,D. and Reeves,P.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-DEC-2001) Microbiology, The University of Sydney,
            Sydney, NSW 2006, Australia
FEATURES             Location/Qualifiers
     source          1..27730
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /serotype="O55:H7"
                     /db_xref="taxon:562"
     gene            204..1199
                     /gene="gne"
     CDS             204..1199
                     /gene="gnu"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-GlcNAc 4-epimerase Gnu"
                     /protein_id="AAL67550.1"
                     /db_xref="GI:18266396"
                     /translation="MNDNVLLIGASGFVGTRLLETAIADFNIKNLDKQQSHFYPEITQ
                     IGDVRDQQALDQALAGFDTVVLLAAEHRDDVSPTSLYYDVNVQGTRNVLAAMEKNGVK
                     NIIFTSSVAVYGLNKHNPDENHPHDPFNHYGKSKWQAEEVLREWYNKAPTERSLTIIR
                     PTVIFGERNRGNVYNLLKQIAGGKFMMVGAGTNYKSMAYVGNIVEFIKYKLKNVAAGY
                     EVYNYVDKPDLNMNQLVAEVEQSLNKKIPSMHLPYPLGMLGGYCFDILSKITGKKYAV
                     SSVRVKKFCATTQFDATKVHSSGFVAPYTLSQGLDRTLQYEFVHAKKDDITFVSE"
     gene            1442..2335
                     /gene="galF"
     CDS             1442..2335
                     /gene="galF"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose pyrophosphorylase GalF"
                     /protein_id="AAL67551.1"
                     /db_xref="GI:18266397"
                     /translation="MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNV
                     RQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRS
                     QVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLS
                     ADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFLKNIEQLLAK"
     gene            2716..3810
                     /gene="wbgM"
     CDS             2716..3810
                     /gene="wbgM"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AAL67552.1"
                     /db_xref="GI:18266398"
                     /translation="MVKILHVHLSGDISGAQRVSLDEMHTLSQEFQQSMVCSKEGRLA
                     EQARCFGVCTHIIPTLTREISLFKDCASLFQLYKIIKKEKFDIVHTHSSKTGFLGRVA
                     AKLAGTKKIVHTVHGFAFPSTENKLIKFIYFLMELIASYCSNIIIVMNESDERIARKY
                     FVKNKKSKLLLINNAIDVDKYNKDKDKDKDKDIFKIVMVGRLCDQKNPLLLIEAIKDL
                     ESNIHVDIIGDGPLKVKLLEKINQYNIADKVSFLGWIDAVEEHLYKYDLFVLPSRWEG
                     MPLAMLEAMAAKVPVLSSDIEANKYLIEKTAGVVFKDEDSKDLKRKINVLHANPELRN
                     NLAHKAYQALIEDFDLTKRTKILESLYLNN"
     gene            3831..4949
                     /gene="gmd"
     CDS             3831..4949
                     /gene="gmd"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose dehydratase Gmd"
                     /protein_id="AAL67553.1"
                     /db_xref="GI:18266399"
                     /translation="MTKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERV
                     DHIYQDPHSAKPNFHLHYGDLTDTSNITRILQEVKPDEVYNLGAMSHVAVSFESPEYT
                     ADVDAIGTLRLLEAIRILGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVA
                     KLYAYWITVNYRESYGIYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYL
                     GNMDSLRDWGHAKDYVRMQWMMLQQEQPEDFVIATGVQYSVREFVEMTAEQLGIKLSF
                     EGKGVDEKGIVVSVTGDKAPGVKTGDVIVAVDPRYFRPAEVETLLGDPAKAHEKLGWK
                     PEITLREMISEMVANDLQTAKKHVLLKSHGFNANLAQE"
     gene            5588..7045
                     /gene="manC"
     CDS             5588..7045
                     /gene="manC"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-P guanosyltransferase ManC"
                     /protein_id="AAL67554.1"
                     /db_xref="GI:18266400"
                     /translation="MSDKSFIAVVMAGGTGSRLWPLSRELYPKQFLKIGGELSLLQST
                     LNRLSKLSFDAPLVITNDNHRFIVAEQLRQMNQLSGNIILEPCGKNTAPAIALAAFSA
                     LKRDKNKDPILLVLAADHIIKNEEAFCEAIKSAMFMAEEDKIVTFGIIPTYAETGYGY
                     INIGARVESNIEVDNAHFYVAKKFVEKPERELAEKYFSSKKYLWNSGMFMFKASVFLS
                     ELKKYRPDIFEVCEEAISASSKDLDFIRLPERMFEKCPSESIDFAVMENTKRCVVCPV
                     DIGWSDVGSWQSLWELSDKSPSGDVCKGDTLTYNTKNNYIYSDSALVAAVGVENIVIV
                     QTKDAVLVANKSEVQDVKKIVDLLKKNNRTEHVTHREVFRPWGKFDSIDQGDRYTVKK
                     IVVKPGEGLSLRMHHHRSEHWIVLSGTAKVILEGTEKLITVNESIYIPLGASYSLENP
                     GVIPLILIEVSSGDYLGEDDIVRQKERYKKKINHE"
     gene            7038..8420
                     /gene="manB"
     CDS             7038..8420
                     /gene="manB"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase ManB"
                     /protein_id="AAL67555.1"
                     /db_xref="GI:18266401"
                     /translation="MNKLTCFKAYDIRGRLGEELNEDIAWRIGRAYGEYLKPKTIVLG
                     GDARLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLDIDGGIEVTASHNPI
                     DYNGMKLVREGARPISGDTGLRDVQRLAELNDFPVIEETKRGRYQRITIRDAYIDHLL
                     GYINPAKLKPMKLVFNSGNGAAGPVVDAIEARFKALGVPVEFIKIHNTPDGNFPNGIP
                     NPLLPECRADTRNAVIEHGADMGVAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLE
                     KYPGEKIVHDPRLSWNTVDVVTAAGGKPVMSKTGHAFIKERMRREDAIYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVAELLCLKGLSLGELIHDRMLAYPASGEINRTLAEPKVAIER
                     VEQYFSHEALSVDRTDGISMSFVDWRFNLRSSNTEPVVRLNVESKGDSEIVIKMTKSI
                     LNILTSGDNK"
     gene            8417..9289
                     /gene="wbgN"
     CDS             8417..9289
                     /gene="wbgN"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AAL67556.1"
                     /db_xref="GI:18266402"
                     /translation="MSIVVARLAGGLGNQMFQYAKGYAESVERNSSLKLDLRGYKNYT
                     LHGGFRLDKLNIDNTFVMSKKEMCIFPNFIVRAINKFPKLSLCSKRFESEQYSKKING
                     SMKGSVEFIGFWQNERYFLEHKEKLREIFTPININLDAKELSDVIRCTNSVSVHIRRG
                     DYVSNVEALKIHGLCTERYYIDSIRYLKERFNNLVFFVFSDDIEWCKKYKNEIFSRSD
                     DVKFIEGNTQEVDMWLMSNAKYHIIANSSFSWWGAWLKNYDLGITIAPTPWFEREELN
                     SFDPCPEKWVRIEK"
     gene            9301..10278
                     /gene="wzy"
     CDS             9301..10278
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AAL67557.1"
                     /db_xref="GI:18266403"
                     /translation="MFNKKYVVIIWGGVLSLLCSLPLSIQGGFDDSLVYYEQAIYIWN
                     NGLLEGLSSIYHQTNKFEIGMGLFFYLQGFLGEGRFVFILLNLFLVNFLAVLIYLKIN
                     DEVRISPSLLCVTLMLMSYYVFSNNIYVWRSIICLYFLVLMIYSKTKYKKIIFIGLGL
                     LFHYTFILFLCVYYFCRVNKIGKFKFVIVSIIISFIISNFLYWMSYASLFVSGGELSL
                     FMSQDNEALKRLIISGTFLFLLLMINLESETNNWVLYKLSLFFCILSIFLCDNWQLSW
                     RVFVPAAILGTAIILSNIKKKDSVVLLGITLSIIPTFRLIFNLLILGHP"
     gene            10296..11573
                     /gene="wzx"
     CDS             10296..11573
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AAL67558.1"
                     /db_xref="GI:18266404"
                     /translation="MIKKMFSSGFIKNGISNYICVAWMGGVSIIVLPYYLHILGPQQW
                     GIVAICISIQSLMYLADAGMSQIMPRDIARCNGKSRELYVIYKSFLHAYSLLAIIVFS
                     LILVGSYFIIDFWLVLDFSLKKEVFICVVLLGLQFLFQFPNNANIGYWNGTLQQHKSN
                     IRQCFFFTLKHIVAICLVTKWPQAILYQSGFLLIAFLESTSNTIKILFSFDGNIKRQE
                     KLSIGINKIFRESGVLSIAVAIGLLVTQLDRIVLSKYVDISDFGYYVLASTLAQYFLQ
                     LQYPLLRLFFPRLTVALNKQNILRLLYSIIIFCVFPCLIMVLISPFFLSLWLDNAEAE
                     SIIIWPLRLILIAIAINSIYNIIYQIMLIKQKAIVILCINISSLLCVFPTIWLLSTRV
                     GVLAGGIGWVLCSLIQLFISLLWLFKRKESILL"
     gene            11570..12367
                     /gene="wbgO"
     CDS             11570..12367
                     /gene="wbgO"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AAL67559.1"
                     /db_xref="GI:18266405"
                     /translation="MIIDEAESAESTHPVVSVILPVNKKNPFLDEAINSILSQTFSSF
                     EIIIVANCCTDDFYNELKHKVNDKIKLIRTNIAYLPYSLNKAIDLSNGEFIARMDSDD
                     ISHPDRFTKQVDFLKNNPYVDVVGTNAIFIDDKGREINKTKLPEENLDIVKNLPYKCC
                     IVHPSVMFRKKVIASIGGYMFSNYSEDYELWNRLSLAKIKFQNLPEYLFYYRLHEGQS
                     TAKKNLYMVMVNDLVIKMKCFFLTGNINYLFGGIRTIASFIYCKYIK"
     gene            12372..13127
                     /gene="wbgP"
     CDS             12372..13127
                     /gene="wbgP"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AAL67560.1"
                     /db_xref="GI:18266406"
                     /translation="MIVKTISVVIPCFNCIQTIDKALQSVYDQDYKFIEIVCVDDCST
                     DNTYEHIKTNHPFVKLVKNDINLGPAASRNKGVRFCSGEFVAFLDADDIWFPNKTNIQ
                     IELMDKYGLDFIGASFTINTNDNPSTVSQFEIINLYNLAFKNYFPTPSVIMKRNLVCF
                     NELQRFSEDYDLWLRLAKDKCIMGYVKTPLISLGKPSYGHSGLSSNLIKMQLGEISSI
                     NKNLKGKWICFFAISWSFIKFIRRLCVVFIRKL"
     gene            13211..14617
                     /gene="gnd"
     CDS             13211..14617
                     /gene="gnd"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase Gnd"
                     /protein_id="AAL67561.1"
                     /db_xref="GI:18266407"
                     /translation="MSKQQIGVIGMAVMGRNLALNIESRGYTVSVYNRSREKTEEVVA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAINSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGAGVSGGEEGALKGPSIMPGGQKDAYEMVVPILTKIA
                     AIAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGALNLSNEELASI
                     FNEWNEGELSSYLIDITKDIFNKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAKLASDKAEFVEKVRRALYLGKIVSYA
                     QGFSQLRAASEQYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENKDIANLLLAPY
                     FKHIADEYQQALRDVVSYAVQNGIPVPTFSAAVAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLE"
     gene            14729..15652
                     /gene="wbdJ"
     CDS             14729..15652
                     /gene="wbdJ"
                     /codon_start=1
                     /transl_table=11
                     /product="WbdJ"
                     /protein_id="AAL67562.1"
                     /db_xref="GI:18266408"
                     /translation="MKILLTGSTGMVGRNIVDNNNSNKYELLCPTSSELNLLDNKAVH
                     DYITCHSPDLIIHAAGLVGGIQANIKRPVDFLVSNLKMGVNIVNEAKNCGVKNFINLG
                     SSCMYPKGIDTAISEDALLTGKLEHTNEGYALAKITVAKLCEYITKESEGYHYKTIIP
                     CNLYGKYDKFDEHSSHMIPAVINRIHNAKVNNIKLIEIWGDGESRREFMYAEDFANFI
                     YQAIPNIQRLPCMLNVGLGHDFSINDYYKVIAEEIGYKGSFTHDLTKPVGMRRKLVDI
                     TLLSEFGWKYQFELRDGIKETYKYYLENVYK"
     gene            15649..16815
                     /gene="wbdK"
     CDS             15649..16815
                     /gene="wbdK"
                     /codon_start=1
                     /transl_table=11
                     /product="WbdK"
                     /protein_id="AAL67563.1"
                     /db_xref="GI:18266409"
                     /translation="MINYPLASSTWDDLEYKAIQSVLDSKMFTMGEYVKQYETQFAKT
                     FGSKYAVMVSSGSTANLLMIAALFFTKKPRLKKGDEIIVPAVSWSTTYYPLQQYGLRV
                     KFVDIDINTLNIDIESLKEAVTDSTKAILTVNLLGNPNNFDEINKIIGGRDIILLEDN
                     CESMGATFNNKCAGTFGLMGTFSSFYSHHIATMEGGCIVTDDEEIYHILLCIRAHGWT
                     RNLPKKNKVTGVKSDDQFEESFKFVLPGYNVRPLEMSGAIGIEQLKKLPRFISVRRKN
                     AEYFLDKFKDHPYLDVQQETGESSWFGFSFIIKKDSGVIRKQLVENLNSAGIECRPIV
                     TGNFLKNTDVLKYFDYTVHNNVDNAEYLDKNGLFVGNHQIELFDEIDYLREVLK"
     gene            18730..19896
                     /gene="ugd"
     CDS             18730..19896
                     /gene="ugd"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose-6-dehydrogenase Ugd"
                     /protein_id="AAL67564.1"
                     /db_xref="GI:18266410"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVEINPYAVMVIKSTVPVGFTEAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELSDVADKVYTRDLFGSD"
     gene            19986..21023
                     /gene="wzz"
     CDS             19986..21023
                     /gene="wzz"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant Wzz"
                     /protein_id="AAL67565.1"
                     /db_xref="GI:18266411"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDSEQIDLIDLLV
                     QLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIITQPDVGQIAGYNNAVNVIYGQ
                     AAPKVSDLQETLIGRFSSAFSALAETLDNQEEPEKLTIEPSVKNQQLPLTVSYVGQTA
                     EGAQMKLAQYIQQVDDKVNQELEKDLKDIIALGRKNLQDSLRTQEVVAQEQKDLRIRQ
                     IQEALQYANQAQVTKPQIQQTGEDITQDTLFLLGSEALESMIKHEATRPLVFSPNYYQ
                     TRQNLLDIESLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVL
                     GRNALRNYNAK"
BASE COUNT     7834 a   5428 c   6406 g   8062 t
ORIGIN
        1 taatgtggaa aagattaact ttagattgcc ggaacggaga gagtagattt gcgaccattc
       61 ataaacttac tggatataat gttctaaaag attataatcc tcacactaac tgttaaagct
      121 ggggctgggc agcattgact actcagggaa ggtactcatc tttatcttgt gtttcttacg
      181 taacaaccag actaaagtga tttatgaacg ataacgtttt gctcatagga gcttccggat
      241 tcgtaggaac ccgactactt gaaacggcaa ttgctgactt taatatcaag aacctggaca
      301 aacagcagag ccacttttat ccagaaatca cacagattgg tgatgttcgt gatcaacagg
      361 cactcgacca ggcgttagcc ggttttgaca ctgttgtgct actggcagcg gaacaccgcg
      421 atgacgtcag ccctacttct ctctattatg atgtcaacgt tcagggtacc cgcaatgtgc
      481 tggcggccat ggaaaaaaat ggcgttaaaa atatcatctt taccagttcc gttgctgttt
      541 atggtttgaa caaacacaac cctgacgaaa accatccaca cgatcctttc aaccactacg
      601 gcaaaagtaa gtggcaggca gaggaagtgc tgcgtgaatg gtataacaaa gcaccaacag
      661 aacgttcatt aaccatcatc cgtcctaccg ttatcttcgg tgaacggaac cgcggtaacg
      721 tctataactt gctgaaacag atcgctggcg gcaagtttat gatggtgggc gcagggacta
      781 actataagtc catggcttat gttggaaaca ttgttgagtt tatcaagtac aaactgaaga
      841 atgttgccgc aggttacgag gtttataact acgttgataa gccagacctg aacatgaacc
      901 agttggttgc tgaagttgaa caaagcctga acaaaaagat cccttctatg cacttgcctt
      961 acccactagg aatgctgggt ggatattgct ttgatatcct gagcaaaatt acgggcaaaa
     1021 aatacgctgt cagctctgtg cgcgtgaaaa aattctgcgc aacaacacag tttgacgcaa
     1081 cgaaagtgca ttcttcaggt tttgtggcac cgtatacgct gtcgcaaggt ctggatcgaa
     1141 ctctgcagta tgaattcgtc catgccaaaa aagacgacat aacgtttgtt tctgagtaat
     1201 gcagacgagt cagagaaaaa aggaccaggt tggactacga ttattcggaa agaggtactg
     1261 attaaattat cagtatgtgg atttccgagt aatccgagta acccagatgc tgatggtgtg
     1321 tagtgttatc gtaaggttta atcaaagtta tgcggaacta agctttggta tatagccata
     1381 acgtttggct aacctatggc aataatttac gcactatcag ccacttagag gtaggaaaag
     1441 aatgacgaat ttaaaagcag ttataccggt agcaggtctt gggatgcata tgttgcctgc
     1501 cactaaggcg attcccaaag agatgctacc gatcgtcgac aagccaatga ttcagtacat
     1561 tgttgacgag attgtggctg cagggatcaa agaaatcctc ctggtaactc acgcgtccaa
     1621 gaacgcagtc gaaaaccact tcgacacctc ttatgaatta gaatctctcc ttgaacagcg
     1681 cgtgaagcgt caactactgg cggaagtaca atctatctgt ccgccgggcg tgaccattat
     1741 gaacgtgcgt cagggtgaac ctttaggttt aggccactcc attttatgtg cgcgacctgc
     1801 cattggtgac aatccatttg tcgtggtgct gccagacgtt gtgatcgacg acgccagcgc
     1861 cgacccgttg cgttacaacc ttgctgccat gattgcgcgc ttcaatgaaa cgggccgtag
     1921 ccaggtgctg gcaaaacgta tgccgggtga cctctctgaa tactccgtca tccagaccaa
     1981 agaaccgctg gatcgtgaag gtaaagtcag ccgcattgtt gaatttatcg aaaaaccgga
     2041 tcagccgcag acgctggact cagacataat ggccgttggt cgctatgtgc tttctgccga
     2101 tatttggccg gaacttgaac gcactcaacc tggtgcatgg gggcgtattc agctgactga
     2161 tgctattgcc gaactggcga aaaaacagtc cgttgatgcc atgctgatga ctggtgacag
     2221 ctacgactgt ggtaaaaaaa tgggctatat gcaggcgttc gtgaagtatg ggctgcgcaa
     2281 cctaaaggaa ggtgcgaaat ttctcaagaa tattgagcaa ttacttgcta aataattatg
     2341 tagcacatat gtgaaagcaa gtttaacgat gggggctttt aatatctctg tggtaaagtt
     2401 tgggatgtta ctactatttt ttatgtcaaa taaattgcat tgtgcagata ttgaccttaa
     2461 ctagattttg aacagtttta cacttgtttc taactgaaat tggttagata attgcggcca
     2521 accatgtggt ttgagtgctt catgtgcttt aaatttttgg tatgagaaca gtaatctggt
     2581 agctgttaag ccaggggcgg tagcgtgatg tttttttgaa taaaattaag tgtataaggt
     2641 ttgttcttta tcgctacaac gtactgaatg ttatcagtgt ttatagaatg accatgaatt
     2701 tggattatat ttattatggt aaaaattctg catgtgcacc tgagtggtga cattagtggt
     2761 gctcaacgtg tttcacttga tgagatgcat actttaagtc aagaatttca acaatcgatg
     2821 gtttgttcaa aggagggaag attagctgag caggcccgtt gttttggagt ctgcacacat
     2881 ataattccaa ctttgaccag ggaaatttca ttatttaaag attgtgcatc tctatttcaa
     2941 ttatataaaa taataaaaaa agaaaaattt gatattgtcc atactcattc ctctaaaaca
     3001 ggttttcttg ggcgtgttgc tgcaaaatta gctggtacga aaaaaatagt gcatacggtt
     3061 cacggcttcg catttccttc aactgaaaac aagcttatta agtttatata ctttttgatg
     3121 gagttgatag cctcttattg ttccaatatc attatagtca tgaatgagag cgatgaaaga
     3181 atcgcaagaa aatattttgt taaaaataaa aaatcaaaat tgcttttaat taacaatgca
     3241 atagatgtcg ataaatacaa taaagataaa gataaagata aagataaaga tatttttaaa
     3301 attgttatgg ttggacgatt atgtgaccaa aaaaatccat tgctattaat tgaggcaata
     3361 aaggatttgg aatccaatat ccatgtagat attattggag atggtccact caaggtcaag
     3421 ctattagaga aaataaatca atataacatt gccgataaag taagtttttt gggctggata
     3481 gatgctgtag aagaacattt atataaatat gatctttttg tcttaccgtc tagatgggag
     3541 gggatgccct tagcgatgtt agaggcaatg gcggcaaaag ttcctgtgct atcctcagat
     3601 atcgaagcaa ataaatatct tattgaaaaa acagctggtg tcgtttttaa ggatgaagat
     3661 agcaaggatc tgaaacgaaa aattaatgtt ttacacgcaa atcctgaact tagaaataat
     3721 ctcgcacata aagcgtatca ggcactaata gaagatttcg acctaacaaa acggactaaa
     3781 atattagagt cgttatattt aaataattga ttttataata taggtttttt atgactaaag
     3841 ttgctcttat tactggtgta accggacaag atggatcata cttggcagag tttctgctgg
     3901 aaaaaggtta tgaagttcat ggtattaagc gtcgtgcatc gtcgtttaat actgaacgtg
     3961 ttgatcatat ttatcaagat ccgcattcag ccaagccaaa cttccatttg cactatggtg
     4021 atctcacgga tacttccaac attacgcgta ttctgcaaga agttaaaccg gatgaagtct
     4081 acaacttggg ggctatgagt cacgtggctg tgtcatttga atcaccagag tataccgcgg
     4141 atgttgatgc tattggtaca ttacgcctac tggaagcgat ccgtatcctt ggcttagaga
     4201 agaaaacacg cttttatcaa gcgtccacat ctgaacttta tggtctggta caagaaatac
     4261 ctcagaaaga gacgacacct ttttacccac gttcaccgta tgctgtagcc aaactgtatg
     4321 cttactggat caccgttaac taccgtgagt cttacggtat atatgcttgt aacggaattc
     4381 tatttaacca tgaatctccg cgtcgtggcg aaactttcgt tacgcgcaaa attacccgtg
     4441 caattgccaa cattgctcag gggctagagt cttgccttta cttggggaat atggattcac
     4501 tacgtgactg gggacatgct aaagattatg tcaggatgca gtggatgatg ctacagcagg
     4561 aacaacctga agatttcgtt attgccactg gtgttcagta ctctgtacgt gagtttgtgg
     4621 aaatgactgc agagcaactt ggcatcaaat tgagctttga aggaaaaggt gtagatgaaa
     4681 aaggtattgt tgtttccgtg acgggcgata aagcacctgg cgtcaaaaca ggagacgtca
     4741 tagttgcggt tgacccgcgt tatttccgcc cggcagaagt agaaacattg ttgggtgatc
     4801 cagcaaaagc gcatgaaaaa cttggctgga agcctgaaat tactttacgt gagatgatct
     4861 cagaaatggt cgctaatgat ttgcagacag caaaaaaaca cgtactgttg aaatcgcacg
     4921 gttttaatgc caatttagcc caagagtaac aaactaactt cgtatcatct tggatgtgga
     4981 atttgccaag tggcaaattc cacaaataag aatacagttt actagttgtt aagtatgaaa
     5041 tgtttctttt gtactaaaca tatagtgctg gattgattat taaataatgg ggtcaggata
     5101 ttgttagact atgaggatct tgtaacagtc gtacggtatg cgccattaat ctcaatagac
     5161 ctgataattg agaatgaata tggtgaattt ttactaggca agagatgtaa tagacctgcg
     5221 cagggatatt ggtttgttcc cggagggagg atatataaga atgagacatt caagcaagct
     5281 ttttgccgga taactgaaaa agaaattggt gttaaaatag atattaagct gggggctttt
     5341 tatggtgttt ggcaacattt ttataaagat aatttttcga cggaaaattt ttcaacacac
     5401 tatgttgtta ttgcctttaa aataaaactt ttactatcga atatacaact tcctaaatta
     5461 cagcatgatg agtggaaatg gttttctcca gaacttgcat tgacttgcaa tgaagtacat
     5521 gaaaatactc gtgcttattt tagaactgat aataattttg ttggattaaa cgataaaggg
     5581 gcatgtgatg tctgataagt cattcatagc tgtagttatg gcaggaggga ctggaagtag
     5641 attatggccg ctatcacgtg agttatatcc taaacagttt ttaaaaattg gtggtgaatt
     5701 atcgctgctt cagtcaacgt tgaatagact ttctaaatta tcatttgatg cccccttggt
     5761 tattactaat gacaatcatc gctttattgt agcagagcag ttaaggcaga tgaatcaact
     5821 tagtggtaat ataatactcg aaccttgtgg caaaaatact gcaccagcga ttgctttagc
     5881 cgctttttca gcccttaagc gtgataaaaa taaagaccct atcttattag tgctcgctgc
     5941 agaccatata ataaaaaatg aagaagcatt ttgtgaagcg ataaaatcgg ctatgtttat
     6001 ggctgaagaa gataaaattg tcacttttgg tataatacca acttatgctg aaacgggata
     6061 tggttacata aatattggag cgagagttga atctaatatc gaagttgata acgctcattt
     6121 ttacgtggca aaaaagtttg tagaaaaacc tgaacgtgaa cttgctgaga aatatttttc
     6181 ttcaaaaaaa tatttatgga atagcgggat gtttatgttc aaagcttcag tcttcttatc
     6241 agagttgaaa aaatatcggc ctgatatttt tgaagtatgc gaagaagcca tatcggcatc
     6301 atctaaagat ttggatttta tacgtctacc tgagagaatg tttgagaaat gtccttctga
     6361 gtcaatcgat tttgctgtaa tggaaaacac aaaacgttgt gttgtgtgtc ctgttgatat
     6421 cggatggagt gatgttggct cgtggcaatc attatgggag ctcagtgata aaagtccatc
     6481 aggtgatgta tgtaaaggtg ataccttaac atacaacaca aaaaataatt atatttactc
     6541 tgattctgcg ctagttgctg ctgtaggtgt tgagaatatt gtcatagtgc aaactaagga
     6601 tgcagtatta gtagcaaata aatctgaggt tcaagatgta aagaaaatcg ttgatctcct
     6661 taaaaaaaac aatcgcacag agcatgttac tcatagagaa gtatttagac catgggggaa
     6721 gtttgactct atagatcagg gtgacagata tactgtaaaa aaaatagtag tgaaacccgg
     6781 cgaagggctt tctttgcgta tgcatcacca ccgttctgaa cattggattg ttttgtctgg
     6841 cacagcaaaa gtcattcttg aaggtacaga aaagctaatt acggtaaatg aatcaattta
     6901 tattcctctt ggggcatcct atagtttaga aaatccaggt gttataccat taatattaat
     6961 agaagtaagc tctggtgatt atcttggtga agatgatatt gtcaggcaga aagaaagata
     7021 taaaaagaag attaaccatg aataaattaa cttgtttcaa agcctacgat attcgcggca
     7081 ggctgggcga agagctgaat gaagatatcg cgtggcgaat tggccgcgct tacggcgagt
     7141 accttaagcc aaaaacgatt gtcctcggcg gtgacgcgcg cctgaccagc gagacgctaa
     7201 agttggcgct ggcgaaagga ctacaggatg cgggcgtcga tgtgctggat ataggcatgt
     7261 cgggaaccga agagatttac ttcgccacct ttcacttgga tattgatggc ggtattgaag
     7321 tgactgccag ccataatccg attgattaca acggtatgaa gctggtgcga gagggggcac
     7381 gacccatcag cggtgacacc ggtctgcgcg acgtgcagcg cttggcggaa ttaaatgatt
     7441 tccctgttat tgaagaaaca aaacgtggcc ggtaccagcg cattactatc cgcgatgcct
     7501 acattgacca cctgctgggt tacatcaatc ccgccaaact gaaaccgatg aagctggtgt
     7561 tcaattcagg taacggcgca gcaggtccgg tggttgatgc tattgaagcc cgttttaagg
     7621 cattgggagt gccggttgag ttcatcaaaa tccacaacac gccggatgga aatttcccca
     7681 atggtattcc taatcctctg ctgccggagt gccgggctga tacgcgcaat gcggtgattg
     7741 aacacggcgc ggatatggga gtcgccttcg acggtgattt tgaccgctgc ttcctgttcg
     7801 atgaaaaagg tcagtttatt gagggctatt atattgtcgg cctgttagca gaagcgtttc
     7861 tggagaagta tcccggggag aaaattgtcc acgatccgcg cctgtcctgg aataccgtgg
     7921 atgtggtgac ggcggcaggt ggtaaaccgg tgatgtcaaa aaccgggcat gcgtttatca
     7981 aagaacgcat gcgccgcgaa gatgccattt atggtggcga aatgagcgca caccactatt
     8041 tccgtgattt tgcctattgc gacagcggaa tgatcccctg gttgctggta gcagaattgc
     8101 tgtgtctgaa aggactgtca ctgggagaac tgatccatga ccggatgctg gcctacccgg
     8161 cgagcggaga aataaaccgt acgctggcag agccgaaggt agcaattgag cgtgtggaac
     8221 agtatttttc tcatgaggcg ctgtcggtgg acagaacgga cggtatcagt atgtcgtttg
     8281 tcgactggcg tttcaattta cgctcttcca ataccgaacc ggtggtgcgc ctgaatgtgg
     8341 aatcgaaagg agatagtgaa atcgtaatta aaatgactaa atcgatattg aatatattaa
     8401 catccggaga taataaatga gtatcgtggt tgcacgcttg gctggaggct taggaaatca
     8461 gatgttccag tatgcgaaag gttatgctga gtcagttgag cgaaatagct ctcttaaatt
     8521 agatttgagg gggtataaaa actatacact acatggtggt tttcgtttag ataagttgaa
     8581 tatagataat acatttgtca tgtcaaagaa agaaatgtgt atcttcccta atttcatagt
     8641 gcgtgccatt aataaatttc caaaattatc tttatgtagc aaaaggtttg agtcagagca
     8701 atactcaaag aagataaatg gcagcatgaa aggaagtgtg gagtttatag gtttttggca
     8761 aaatgagagg tattttttag agcataaaga aaaattaaga gagatattta cacctatcaa
     8821 tataaatttg gatgctaaag aattaagtga tgtaattcga tgcaccaatt cagtctccgt
     8881 gcatatacgc cgcggagatt atgtatcgaa cgtcgaagcg ttaaaaatac atgggttgtg
     8941 tactgaaaga tattatattg acagcattcg ttatttaaag gaaaggttta ataacttggt
     9001 tttttttgta tttagtgatg atatcgaatg gtgtaagaaa tataaaaatg aaatattttc
     9061 aaggagtgat gatgtgaagt ttattgaagg gaatactcaa gaggtagata tgtggttaat
     9121 gtcaaatgct aaatatcata taatagctaa tagttcattt agttggtggg gggcgtggct
     9181 aaaaaactat gatctaggta ttacaattgc gccaacgcct tggtttgaga gagaagaact
     9241 taatagtttt gatccatgcc cagagaaatg ggttcgaatt gaaaaataag agtcgtacta
     9301 atgtttaata aaaaatatgt agtgataatt tggggaggag tattatcatt actatgttct
     9361 ttacctctgt ctattcaggg tggttttgac gactcgcttg tttattatga acaagctatt
     9421 tatatttgga ataatggatt actggagggg ttgagttcta tttatcatca aaccaataaa
     9481 tttgaaattg gtatgggatt atttttttac ttgcagggct ttttggggga ggggcggttt
     9541 gtatttattc ttctaaattt gtttttggtg aattttcttg ctgttttaat atatcttaaa
     9601 ataaatgatg aggttagaat tagcccaagt ttgttatgtg ttacactaat gctaatgtct
     9661 tattatgttt tttcgaataa catttatgtg tggcgcagta ttatctgctt atattttctt
     9721 gtattgatga tctattcaaa aacaaaatat aagaaaatta tttttattgg tctcggttta
     9781 ttgtttcatt atacctttat attgtttctt tgtgtatatt atttttgtcg ggtaaataaa
     9841 ataggtaaat ttaaattcgt aattgtatct ataattatct cctttattat ctcaaacttt
     9901 ttatattgga tgagttatgc ttccttattt gtgtcggggg gggagttgtc tctatttatg
     9961 agtcaagata atgaagcttt aaaacgtcta attattagcg gaactttctt gtttttatta
    10021 ttaatgataa acttagagag tgagacgaat aattgggtgt tatataagct ctctttgttt
    10081 ttttgtatat tatcaatatt tttatgtgat aattggcagc tttcctggcg ggtttttgtt
    10141 cccgcggcga tattgggtac tgcaattata ttgtctaata ttaagaaaaa agatagcgtg
    10201 gtgcttttgg ggataacatt atcgataata ccgaccttta gattgatttt taatttatta
    10261 atattagggc atccttaata aagagatttt tatgtatgat aaaaaaaatg ttttcttcag
    10321 gctttattaa gaatgggata tcaaattata tttgtgtggc atggatgggg ggagttagta
    10381 ttattgttct gccatattat ctccacattc ttggtcccca gcaatggggt atagttgcta
    10441 tttgtatatc tatacaatca ttaatgtatt tggcagacgc tggcatgtcc caaataatgc
    10501 caagagatat tgcaagatgt aatggtaagt ctagagaact ttatgtaatc tataagtctt
    10561 ttctacatgc atattcgctt ttagctatta ttgtgttttc attgatttta gtggggagct
    10621 atttcatcat tgacttttgg ttagttttgg atttttcctt aaagaaagag gtttttattt
    10681 gcgttgtcct gttaggattg cagtttttat ttcagttccc taacaatgct aatataggtt
    10741 actggaatgg aacattgcaa cagcataaat caaatataag acaatgcttt ttttttacat
    10801 taaaacacat tgttgctatt tgtcttgtaa ctaagtggcc acaggcaatc ttatatcaaa
    10861 gtggttttct tttgattgct tttctggaat ccacaagtaa tactataaaa atacttttta
    10921 gttttgatgg caatattaaa aggcaggaaa aactatcaat tggcataaat aaaatttttc
    10981 gtgaaagtgg tgttttatca atcgctgtag ctataggatt gctagttaca cagcttgata
    11041 gaattgttct tagtaaatat gttgacatta gtgattttgg gtattacgta ttggcatcta
    11101 cgttggctca atattttctt cagttacaat atcctttatt aaggctcttt ttcccacgat
    11161 tgacagtggc cttgaataaa caaaatattt tgaggttgct atatagcata attatatttt
    11221 gtgttttccc ttgtctcatt atggttctga tttctccatt tttcctaagt ttatggcttg
    11281 ataatgctga agcagaatct ataattattt ggccattgcg gttaatttta atcgcaattg
    11341 caataaactc tatttataac ataatttatc agattatgtt aataaaacaa aaagcaatag
    11401 taatactgtg tatcaatatc tcttcgttac tgtgtgtatt tccaacaatt tggcttttat
    11461 ctactagagt tggggtttta gcgggaggta taggttgggt gttatgttcg ttaattcaat
    11521 tatttatatc actgttatgg ttatttaaaa ggaaagagag tatattgtta tgataatcga
    11581 tgaagctgaa tctgccgaat caactcatcc tgttgtttct gttattctgc cagttaataa
    11641 aaaaaaccct tttcttgatg aggcaataaa tagtatttta tcgcaaacat tttcgtcatt
    11701 cgagataata atagttgcaa attgttgtac ggatgatttt tataatgagt tgaaacacaa
    11761 agttaatgac aaaattaagt tgattcgtac aaatattgct tatttaccgt actcattaaa
    11821 taaagccatc gatttgtcca atggtgagtt tattgcaagg atggattccg atgatatttc
    11881 tcatcctgat agattcacga aacaagttga ttttttaaaa aataatcctt atgtggatgt
    11941 cgtcggtact aatgcaatat ttattgatga taaaggtcga gaaataaaca aaacaaagct
    12001 acctgaagaa aatttggata ttgtaaaaaa cttaccgtat aaatgttgca ttgttcatcc
    12061 atctgtaatg tttaggaaga aagtaatcgc ttcaattggc ggttatatgt tttcaaacta
    12121 ttctgaggat tatgagttat ggaatagatt aagtttagca aaaataaaat ttcaaaattt
    12181 accggaatat ttattctatt acaggttgca tgaaggtcag tcaactgcta aaaaaaactt
    12241 gtatatggtt atggtaaatg atttggtaat aaagatgaaa tgcttttttt tgacaggtaa
    12301 tatcaactat ctcttcggag ggattagaac tattgcttct tttatatact gtaaatacat
    12361 aaagtgagat attgattgtg aaaacaataa gtgtcgttat tccttgcttt aattgcattc
    12421 aaactataga taaagcattg caatcagtat acgatcaaga ctacaaattt atagagatcg
    12481 tttgcgttga tgattgttcg acagataata cgtatgaaca tattaaaaca aatcaccctt
    12541 tcgtaaagct tgtgaagaat gacattaatt taggtccggc agcaagtcga aataaaggtg
    12601 ttcgcttttg ttctggcgag tttgtggcat ttttagatgc tgacgacata tggtttccta
    12661 ataaaacaaa tattcaaatt gagttgatgg ataaatatgg gttggatttc attggtgcat
    12721 catttaccat taatactaat gataatccaa gcactgtgtc ccagttcgaa attataaatc
    12781 tttataacct tgcgttcaag aattatttcc caactccatc agtaataatg aaaaggaatt
    12841 tggtttgctt taatgaatta caaagatttt ctgaagacta tgatttatgg ctaaggttag
    12901 ctaaagataa atgtataatg ggttatgtca aaacaccatt aatatctctt ggcaaaccaa
    12961 gttatggaca ctctgggctc agttcaaatt tgatcaagat gcaacttggt gagatatctt
    13021 cgataaataa aaatcttaaa ggaaagtgga tctgtttttt tgccatatct tggtctttta
    13081 ttaaatttat tcgtagatta tgtgtggttt ttatccggaa gttataaatg aagccagtat
    13141 ttttacctgg aataatattg aattaaagta tttacattag ctggttaaag ataaataata
    13201 ggagtatgta atgtccaagc aacagatcgg cgtcatcggt atggctgtga tggggcgcaa
    13261 cttggctcta aacatcgaga gccgtggtta taccgtatcc gtctataatc gctcgcgtga
    13321 aaaaactgaa gaggttgttg ccgaaaaccc aggtaagaaa ctggtccctt attacacggt
    13381 taaagagttc gtcgagtctc ttgaaactcc acgccgtatc ctgttaatgg tcaaagcggg
    13441 tgctggcact gatgctgcga ttaattccct gaagccctat ctagataaag gcgacatcat
    13501 cattgatggc ggtaatacct tctttcagga cacaattcgt cgtaaccgtg aactttccgc
    13561 ggaaggcttt aactttatcg gggccggggt ttcaggtggt gaagagggcg cgctgaaagg
    13621 cccatctatc atgcctggtg gccagaaaga tgcgtatgaa atggttgtgc caatcctgac
    13681 caagattgcc gcgatagctg aagatggtga accgtgcgtg acgtatattg gtgcggatgg
    13741 tgcaggtcat tacgtgaaga tggtgcacaa cggtatcgaa tatggcgata tgcaattgat
    13801 agctgaagcc tattctctgc tgaaaggtgc cctaaatctg tctaatgaag agttagcctc
    13861 tatctttaat gaatggaatg aaggcgagct gagcagctat ctgattgaca tcactaagga
    13921 tatcttcaac aaaaaagatg aagagggtaa atacttggtt gatgtgattt tggacgaagc
    13981 tgcgaacaaa ggtacaggca aatggaccag ccagagctct cttgatctag gcgaaccgct
    14041 gtcgttgatc accgaatccg tatttgcccg ctacatctcc tctctgaaag accagcgtgt
    14101 tgcggcctct aaagtgctgt ctggcccgca ggctaaactg gctagtgata aagctgagtt
    14161 tgttgagaaa gtacgccgtg ccttgtacct aggcaaaatt gtctcttatg cccaaggctt
    14221 ttctcaactt cgtgccgcat cagagcaata caactgggat ttgaactacg gtgaaatcgc
    14281 gaaaattttc cgcgcaggct gcattattcg tgcacagttc ctccagaaaa tcaccgacgc
    14341 ttatgctgaa aacaaagata ttgcaaacct gctgcttgct ccgtatttca aacatatcgc
    14401 tgatgaatat caacaagccc tccgtgatgt agtgtcttat gctgtgcaga acggtattcc
    14461 ggtaccgact ttctccgccg ctgtagctta ctacgacagc taccgttctg cggttctgcc
    14521 ggctaacttg atccaagcac agcgtgatta tttcggtgcg cacacgtata aacgcattga
    14581 taaagaaggt gtttttcata cagaatggct agaataacga tgcaataatc ttaaatttgc
    14641 gatcttaaga ggagctaatg atgtcacgga tcgcgatttt gaaatcttta agttagatat
    14701 attcatcagg ttatatgtta gaggtcatat gaaaattctg ttgacgggct caactgggat
    14761 ggtcggtcgt aatattgttg ataataataa ttcaaacaag tatgagctat tatgcccgac
    14821 tagttctgag ctaaatttgc ttgataataa agctgttcat gactacatca catgtcattc
    14881 tcctgatttg attattcatg cggcaggttt agtcggtgga attcaagcga atataaaacg
    14941 ccctgttgat tttcttgtct caaacctgaa aatgggtgtt aacattgtaa atgaggctaa
    15001 aaattgtggt gttaagaact ttataaattt aggaagctct tgcatgtacc ctaaaggtat
    15061 tgacactgca atttctgaag atgctttgct tacaggtaag ttagaacaca ctaatgaagg
    15121 gtatgcactt gctaaaatca cagtggcaaa attgtgcgag tatataacta aagagagtga
    15181 aggttatcat tataaaacga ttataccatg taatttatat gggaaatatg ataagtttga
    15241 tgagcattcc tcacacatga ttcctgctgt tataaataga atacataatg ctaaagttaa
    15301 taatataaaa ttgattgaaa tttgggggga cggtgagtcc cgtcgtgaat ttatgtatgc
    15361 cgaagacttt gcgaatttta tttaccaagc gattccaaat attcagcgat taccatgtat
    15421 gttaaacgtt gggttaggtc atgatttctc gattaatgat tattataaag ttatagctga
    15481 agaaatagga tataaaggta gttttactca tgatttaaca aagcctgttg gtatgagaag
    15541 aaaacttgtt gatattacct tgctgagtga gtttggttgg aaatatcagt ttgaattgag
    15601 agatggtata aaagaaacct ataagtatta tttggagaat gtgtataaat gattaactac
    15661 ccattagcaa gtagcacttg ggatgattta gaatataaag caatccaatc agttttagac
    15721 tctaaaatgt tcacgatggg ggagtatgta aaacaatacg aaacccaatt tgcaaagact
    15781 tttggaagta aatatgccgt gatggtgagt tcagggtcta cagcaaattt attaatgatt
    15841 gctgcattgt ttttcacaaa aaaaccgaga ttaaaaaagg gggatgaaat aatagttcct
    15901 gctgtttctt ggtcaactac ttattatccg ttgcaacaat atggattgag ggtgaagttt
    15961 gttgatatcg atattaatac cttaaatatt gatattgaaa gtttgaaaga agctgtaaca
    16021 gatagtacaa aagcaatact cacggtaaat ttattaggta atcctaataa cttcgatgaa
    16081 attaataaaa ttattggagg tagagatatt atcttattgg aagataactg tgagtctatg
    16141 ggagcaacct ttaataataa atgcgccggc acttttggtc tgatgggaac atttagctct
    16201 ttctattctc atcatatagc taccatggaa gggggatgca ttgtcactga tgatgaagaa
    16261 atttatcata tcttgctgtg cattcgagct catggttgga cgcgtaattt accgaaaaaa
    16321 aataaagtta caggtgtgaa gagtgatgat caatttgaag agtcattcaa attcgtttta
    16381 cccggctata atgttaggcc attggaaatg agtggtgcaa taggcataga acaattaaaa
    16441 aaattgccaa gatttatttc tgttagaaga aaaaatgcag agtattttct tgataaattt
    16501 aaggatcatc catacttgga cgtgcagcag gaaactggcg agagtagctg gtttggtttc
    16561 tcatttatca taaaaaaaga ttctggtgtc attaggaaac aacttgttga aaatttaaat
    16621 tctgctggta ttgagtgtag accaattgtc actggtaact ttctgaaaaa tacagatgtt
    16681 cttaaatatt tcgactatac cgttcataac aatgtagata acgctgagta tttagataaa
    16741 aatggtcttt ttgttggaaa tcatcagata gaactatttg atgagattga ttatctcaga
    16801 gaggttttga aatgataaaa agtgaatgac tcttgattta atgcttatgg gtaattttta
    16861 tttgaatacg ttccatttat ttagattata ttgagtttat ccatacaata gctgttataa
    16921 acactaatat tatagtttaa gttacgaact ctatctgtct atagatagtt gtttatattt
    16981 tttgccagcg caagttagag gcggcatttt atagctgttg cgtttaatac gtctagctgg
    17041 aagtttgttt tatgactaga tacagtagca atatggttac ttgagaattt atgcagttta
    17101 attgtggcat tgaagaaatc atggttgcta tggcatagct agattaatct ggtttagtct
    17161 tactgtgaat ctaggcctgg agcgctcctc cgggcttttt tgtgcacaga aaactgatct
    17221 tacccagcaa tagtggacac acggctaagt gagtaaactc tcagtcagag gcagggaaag
    17281 atcatgtaac gctgcttttt tgtactaaat aattcgcatt ttatgttcaa aaattgagat
    17341 attcctcatc acctgaagct gttttttatt gcttatacat gatcaaatac tccttacata
    17401 attaaggaga acaaagtgga acttaaaaaa ttgatggagc atatttctat tatccccgat
    17461 tacagacaag cctggaaaat ggaacataaa ttatcggata ttctactgtt gactatttgt
    17521 gccgttattt ctggtgcaga aggttgggaa gatatagagg attttgggga atcacatctc
    17581 gattttttga agcaatatgg tgattttgaa aatggtattc ctgttcacga taccattgcc
    17641 agagttgtat cctgtatcag tcctgcaaaa tttcacgagt gctttattaa ctggatgcgt
    17701 gacggccatt cttcagatga taaagacgtc attgcaattg atggaaaaac gctccagcac
    17761 tcttatgaca agagtcgccg caggggagcg attcatgcca ttagtgcgtt ctcaacaatg
    17821 cacagtctgg tcatcggaca gatcaagacg gatgagaaat ctaatgagat tacagctatc
    17881 ccggaaattc ttaacatgct ggacattaat ggaaaaatca tcaaaactga tgcgatgggg
    17941 tgccagaaag atattagtga aaaaagtcac ggcagagaag aaatccgtct tcatattgtt
    18001 tgcgatgtcc ctgatgaact tattgatttc acgttttaat ggaaagggct gaagaaatta
    18061 tgcgtggcag tctcctttcg gtccataata gcagaacaaa agaaagagcc agaaatgacg
    18121 gtcagatatt atatcagttc tgctgattta accgcagaga agttcgccac agcaatccga
    18181 aaccactggc acgtggagaa taagttgcac tggcgtctgg acgtggtaat gaatgaagac
    18241 gactgcaaaa taagaagagg aaatgcagcc gaattatttt cagggatacg gcacattgca
    18301 ttaatatttt gacgaatgat aaggtattca aggcagggtt aagacgtaag atgagaaaag
    18361 cagccatgga cagagactat ctcgcgtcag tccttgcggg gtgcgggctt tcgtaagctt
    18421 gccctgtaac gaagttggat gcaaatgtca gatcgtgtgc gcctgttagg gcgtggttgg
    18481 taagatagcc ttataggcgc atttgaaaaa cctccggcta tggtggagga tatttatttg
    18541 ccaattatct tataaactaa atttcacggc ttaatattaa cttaataaat atcagctatc
    18601 tttataaaga aaatctgaat tgtttttcgt tgcgttgacc atcgaacaac gtagcgttaa
    18661 aacttttagc tcttatcagg atgctaaaaa catcatgatt cacagttaag ttaattctga
    18721 gagcatgaaa tgaaaatcac catttccggt actggctatg taggcttatc aaacgggctt
    18781 ctaatcgcac aaaatcatga ggttgtggca ttagatattt taccgtcacg cgttgctatg
    18841 ctgaatgatc ggatatctcc tattgttgat aaggaaattc agcagttttt gcaatcagat
    18901 aaaatacact ttaatgccac attagataaa aatgaagcct accgggatgc tgattatgtc
    18961 atcatcgcca ctccaaccga ctatgatcct aaaactaatt atttcaatac atccagtgta
    19021 gaatcagtaa ttaaagacgt agttgagata aatccttatg cggttatggt catcaaatca
    19081 acggttcccg ttggttttac cgaagcgatg cataagaaat atcgtactga aaatattatt
    19141 ttctctccgg aatttctccg tgaaggtaaa gccctttacg ataatctcca tccttcacgt
    19201 attgtcatcg gtgagcgttc agaacgcgca gaacgttttg ctgcgttgtt acaggaaggc
    19261 gcgattaagc aaaatatccc gaccctgttc accgattcga ccgaagcaga agcgattaaa
    19321 ctttttgcaa acacctacct ggcgatgcgc gtggcatact ttaacgaact ggatagctac
    19381 gcagaaagtt taggtctgaa tactcgccag attatcgaag gcgtttgtct cgatccgcgt
    19441 attggcaacc attacaacaa cccgtcgttt ggttatggtg gttattgctt gccgaaagat
    19501 accaagcagt tactggcgaa ctatcagtct gtgccgaata acctgatctc ggcaattgtc
    19561 gatgcaaacc gcacgcgtaa ggattttatt gccgatgcca ttttgtcacg caaaccgcaa
    19621 gtggtgggta tttatcgtct gattatgaag agcggttcag ataacttccg tgcgtcttct
    19681 attcagggga ttatgaaacg tatcaaggcg aaaggcgttg aagtgatcat ctacgagcca
    19741 gtgatgaaag aagattcatt cttcaactct cgcctggaac gtgatctcgc caccttcaaa
    19801 caacaagccg acgtcattat ttccaaccgt atggcagaag agcttagtga tgtggcagat
    19861 aaggtataca cccgcgatct ctttggcagt gactaacatc ctgttatcag ggcgattttc
    19921 gccctgattc tcttatgttc cctttgtaat aattcattat ttttatcatt tatcctatag
    19981 cattcatggc gattatcgct aaactatggc gacttaaaat tatttcgtcc gttagggtaa
    20041 tgatgagagt agaaaataat aatgtttctg ggcaaaacca tgactcggaa cagattgatt
    20101 tgattgattt actagtgcag ttgtggcgtg gcaagatgac aatcatcatt tccgtcattg
    20161 tggctattgc cctggctatt ggatatttgg cagtagcgaa ggagaaatgg acgtcaacag
    20221 caattatcac tcagcccgac gtgggacaaa ttgctggcta taacaatgcc gtgaatgtta
    20281 tctatggtca ggctgcaccg aaagtatcgg atttacagga gacgttaatt ggtcgcttca
    20341 gttctgcctt ctctgcatta gcagaaacgc tggataatca ggaagaacca gaaaaactta
    20401 ccatcgaacc ttctgttaag aaccagcaat taccattgac tgtttcttat gttgggcaaa
    20461 ctgcagaggg agcacaaatg aagttggccc aatacattca gcaagttgat gataaagtga
    20521 atcaagagct agaaaaggat ctcaaagaca tcattgctct gggacggaaa aacttgcagg
    20581 actctttaag aacgcaggaa gtggttgcgc aggagcagaa agatctgcgt atccgtcaga
    20641 ttcaggaagc gttgcagtat gcgaatcagg cgcaggtgac aaaaccgcaa attcaacaga
    20701 ctggcgaaga tatcacgcaa gatacgttgt tccttttggg gagcgaagcg ctggagtcga
    20761 tgattaagca tgaggcgacc cgtccgttgg tgttctcacc aaactactat cagactcgtc
    20821 aaaacctgct ggatatcgaa agcttaaaag ttgatgatct tgatattcat gcttaccgtt
    20881 atgtaatgaa accgacgtta cctattcgtc gcgatagccc gaaaaaggca atcaccttga
    20941 ttctggcggt gctgctgggc ggcatggttg gcgcggggat tgtgttgggg cgtaatgctc
    21001 tgcgtaatta caacgcgaag taatcttttc ggttttaaag aaaatgggca gggtggtggc
    21061 accttgcccg ttttttttgc cggatgcgac gacaacatcg catccgctta tccctcaact
    21121 cactgatgcc gtttacgcag gttctcaatc accgtcgtta aatccagccc ctgatcctgc
    21181 aacagcacca acaggtgata catcaaatca gatgcctcgt tggtcagctc aaagcggtca
    21241 tgtaccgtcg cggccagtgc ggtttccacg ccttcttcgc ccactttctg cgcaatgcgt
    21301 ttggtgccgc tggcatacag tttggcggtg taagaagttt ccgggtcggc agatttgcgt
    21361 tcggcgagca gttgttccag ttgataaagg aacagccact ggtgagtggt gtcgccgaag
    21421 cagctgctgg tgcctttgtg gcaggtcggg ccgatgggat tcgccagcaa cagtaacgtg
    21481 tcgttgtcgc agtccggcgt aatatttact acgttgagga aattgcccga cgtttcgcct
    21541 ttggtccaca gtcgctgttt agtgcgcgag aagaaggtga ctttgccgct ttcgatggtt
    21601 ttatctaagg cttccgggtt catatagccc agcattaaca cttcaccgga taccgcgtgt
    21661 tgcacaatca ccggcataag tccgtcagtt ttttcccagt ccagttcgcg acgttgttgt
    21721 tctgttaaca tatcctgatc tccacgccct gtgttgccag gtacgctttt aattcaccaa
    21781 tattgattat ttgtttgtgg aatacggaag ctgccagcgc accgtcaacg tcggcatcgc
    21841 ggaaagcttc gaggaagtgt tccatggtgc ccgcgccacc ggaggcaatt agcgggacgt
    21901 ggcaaacttc acgcactttt ttcagttgtt cgaggtcgta accgttacgc acgccgtcct
    21961 gattcatcat gttgaggacg atttctccgg caccgcgttt ttgcacttcc tgtacccagt
    22021 cgagcgtttc ccactgagtg acgcgggtgc ggctttcatc gccggtatat tgattcacat
    22081 gatatttacc ggtttcagtg tcgtaccagg tatcaatccc caccacaata cactgcacgc
    22141 caaaacgatc cgccaggcga gtaattaacg tcggatccgc cagcgcaggc gagttgatgg
    22201 aaattttatc cgcgccaaag gaaagaattt tcgcggcatc ttccagagac ttaatcccac
    22261 ccgccacaca aaacggaatg tcgattactt ccgccacgcg agatacccag cttttatcta
    22321 ccacacggcc atcgctggaa gcggtgatat cgtagaacac cagttcgtct gcaccttcct
    22381 cagcgtagcg ttttgccagc ggtacaatat cgccaatgat ttcatggttg cgaaactgta
    22441 cgcctttcac cacctgacca tcgcgaacgt cgagacacgg aattatacgt tttgccagca
    22501 tgcgatggcc tccttcacgg tgaatttacc ttccagtaat gcacgaccaa ctattacgcc
    22561 gcgcacgcca gtgccacgca gggcagcaac atcgttaatg tcgccaatac cgccggagga
    22621 ctgaaatgcc acctgcgggt atctggcgca cacttcttca tataaagaga cgttagagcc
    22681 tgccagcgtg ccgtcgcgcg agatatcggt acacagcaca tgtttcaggc cgacgggcag
    22741 ataggtttcc accagttgtt ccagtgaaac gcccgaattc tcttgccagc cgctgaccgc
    22801 cacctgcttg ttgccttgct cgtcaatacg gacatccagc gccagcacta aggcatcggc
    22861 accgaagcgt tcaaaccagc ctttcaccct ttctggtgat ttcaccgcgg tggagccaac
    22921 caccacgcgc gcaacgcccg cttccagtaa cgccgccacg tcttcttcgc tacgcacacc
    22981 gccgccaacc tgcaccggaa cgttaacgcc cgcgaccagg gttttaatca gcgggatttg
    23041 acgttttgcc ggatcttttg ccccggtcag atccaccaga tgcaacactt cggcaccttg
    23101 cgcagcgtaa tcctgtaagc gtggcagcgg gtcgttaccg taatcgcgtt gtttgccata
    23161 atcgccctga tggagacgca ccacggtgcc gtcaattaaa tctaatgccg gaataatcat
    23221 cacatctcca ggaagttttt cagcaactta gcgccagcgg caccagaacg ctccgggtgg
    23281 aactgcacgc cgtagaagtt atctttttgt accgccgcag tgaacggttc gccgtaatta
    23341 ctctgggcga tggtccacgg attgactggc attgcgtagc tgtgaacaaa gtaaaagtac
    23401 gcgccatctt caatcccctg aaacaggcgg ttgcctgcct gcgggtaaac gcggttccag
    23461 cccatatgcg gcagcggcag accaaagtcg gtcattttcg gcacgtcttc gtcaatgatg
    23521 cccagcaagt cgacgccgtt gctctcttcg ctgcgccgcc caagcagttg catccctaag
    23581 cagatgccca gcaccggttg ggtacaggct ttgatgagat caaacagctc gcgctcacgc
    23641 acctgatcca tcgctgcttg tgcagtgcca acgccgggta aaaatagttt atcggccagc
    23701 aacacgacgt ccgggtcacg gctgactttg ggttcataac cgtggcgcgc aatggcagac
    23761 ttcaccgagt tcaggttggc gcagccagta tcaaggatca ccacgttcat tacagcactc
    23821 ctttcgacga gggcagggta tcgccttcca cgcggatggc ctggcgcagg gtgcgaccaa
    23881 aagctttgaa caggctctct acacggtggt gatcgttttt acctttggtt ttcaggtgca
    23941 gggtcacgcc catggtgtat gagagcgaac ggaagaagtg ctcgatcatt tcggtgctga
    24001 gatcgcccac gcgctggtag gtaaattcgg ccttatattc caggtgcggg cgaccagaga
    24061 tatccagtgc acagcgggca aggcattcgt ccatcggtag cacaaaacca aagcgacaaa
    24121 taccgcgttt atcgccgagg gcaattttta acgcttcgcc cagcgccagg ccggtatctt
    24181 cgacggtgtg gtgatcgtcg atatagaggt cgcctttgac gttgatttcc atgcggaaac
    24241 cgccgtgggt ggcgatctga tccagcatgt gatcaaagaa gccaacgccg gtgttaatct
    24301 tgctgccacc ttcgcgatcc agccacacct ggacgtcaat ttgcgtctct ttggtgttgc
    24361 gcactacatg ggcgtaacgg tctcgtttag tgagctgctc gccaatcatt ggccagttca
    24421 gggtttcgcg gtcatagcgt aaaccattaa tgcccatgtt ttccgccagc tgaatatcgg
    24481 tcgcgcgatc gccaatcaca taactattgg cacgatccat cgcttgctca gcgagataac
    24541 gctccaccag ttttactttc ggcttacggc agtcgcactc atcggcgggc aggtgcggac
    24601 aaatcagcac ttcatcaaac tgcacgcctt gcgaggtgaa gatctgcatc atcaggttgt
    24661 gcgggccatc aaaatccgcc tgcgggaaac tttgtgttcc aagaccatct tgattggtga
    24721 tcatcaccag cttgtagccc gctttttgca gcttcagcag ctccgggatc acgcccggtt
    24781 caaaggcgag tttgtcaaaa cggtccacct gaaaatcact cggcggttcg ctaatcaggg
    24841 ttccatcgcg atcgataaaa agatacttct gactcattaa acttgctccg cacgtaaggc
    24901 gtcaatgacg cgctggcttt cttcacgggt tccgacggta attcgcaggc agccgcttaa
    24961 agagggttgt ttattctgat cacgtaagat aatgccctga tcccacaaag atttaaacac
    25021 tgcgctggag gctttaaagc gcgccagaat gtagttggtt tcagagttaa aaacctgctc
    25081 cacgcagggg atctctttca gtgcggcaat caggtattcg cgttctgcaa taatttgcgc
    25141 tacccgttcg cgcatggcga cgatcccctg cgggcttaac gcctgggccg caatgtcggc
    25201 aaccggcgtc gagagcgggt agggggcgat cactttcatc aacaggttga tgacttcttc
    25261 gtttgccagc gtaaacccac aacgaaggcc cgccagagca aaagctttcg acagtgtgcg
    25321 caaaatagcc aggtgcggat attccgtcag ccagccagcc agcgatgcct gtgggcaaaa
    25381 ctctatatag gcttcatcgg caactacaat cgccttaccg cgggttaact ccagcagggt
    25441 gcgaaaatcc tgcggattga tcagttgccc ggtcgggttg ttggggctgc aaacatagac
    25501 cacttttacg ccgtccagct tgtcggaaat gccctgcaag tccagttgcc agttgtccag
    25561 cgtcggcact gtgcggcact cgacgccaat ggtttcagcg ctgacgctgt acatgccgta
    25621 cgttggcggg cagtagagga tggcgtcttt acctggttcg caaaaagcgc gaatcagtag
    25681 ttcaatacct tcgtccgcgc cacggctgac cagcacctgc tccggtttta cgcctgcata
    25741 ctgcgcgtaa ttttcaatca ccgctttcgg ctgacattcc gggtagcggt tgagcgtttg
    25801 ctgagtaagc tgaaactcca cggttgtggg gtattcgttg gcgttcagcc agacgtcgcc
    25861 gttaccgccc agacgacgcg ccgactgata cggcgtcagg ttgcggacgt tttcacgcgc
    25921 taaatcggta atagtcacgg tgctcatgct tgctccttaa gggcgttaac acgcaaagta
    25981 acggcatttt tatgggcggt caggcgctcg gcggcggcca gtgtttctat ggtcgaagcc
    26041 agctcggaga aaccttcttt cgacagttcc tgcacggtca tacgcttctg gaaatctgcc
    26101 agcccgaggc tggaacaggt ggcggtgtaa ccgtaagtcg gcagtacgtg gttggtgccg
    26161 gaggcgtaat cacccgccga ttcgggtgac cagtcaccaa gaaataccga accggcgctg
    26221 gtgatgccat cgaccagatc gcgggcgttg cgggtctgga tgatcaggtg ctccgggccg
    26281 tactggttgg agatctctac gcactgcgct aaatctttag tcacgatcag acggctggcg
    26341 ctcagtgcct gacgggcggt ttcggcacgc ggcagctctg ccaactggcg ttcgacagct
    26401 tcggctacgc cacgcgccat atcagcagcg ggtgtcagta aaatcacctg agagtccggg
    26461 ccgtgttcag cctgggagag caaatcagaa gccacgaaat caggcgtagc accgctgtcg
    26521 gcaatgacca gcacttccga cgggcctgcg ggcatatcga tcgccgcacc gtccagacgc
    26581 tggcttacct ggcgttttgc ttcggtgaca aaggcgttgc ctggcccgaa gattttgtcc
    26641 acttttggca cagattccgt accaaacgcc agtgcggcaa tggcctgtgc gccgccgacg
    26701 ttaaacacgt cctgcacgcc gcacagctgc gccgcgtaaa gaatttcatc ggcaatcggc
    26761 ggcggtgagc acagcaccac ttttttacag cccgctatac gcgccggagt cgccagcatt
    26821 aataccgttg agaagagcgg ggcggagccg ccaggaatat acaaacccac tgaagccacc
    26881 gggcgcgtga cttgctggca acgtacgcct ggctgcgttt ctacatctac tggcggcagt
    26941 ttttgcgcag tgtggaaggt ttcaatattc tttactgcca ccgccatcgc ctgttttagc
    27001 tcgtcgctca ggcgttcgca ggcggcggca atttcctcag cagacatctt cagcgcggta
    27061 accgtggttt tatcaaactt cgcgctgtat tcccgcaggg cgtcatcacc gcgtgctttc
    27121 acgttatcga gaatatcgtt aacagtgcgg gtaatgcttt cagaagcgga gatcgccggg
    27181 cgcattaaca gctggcgttg ttgctctgca gtacagctat tccagtcaat gattgtgtta
    27241 aagctcatgg cgatcactcc atcatcttct caatcggcag gaccaggatt gaactggcac
    27301 ccagcgcttt cagtttttcc atcgtttccc agaacagggt ttcgctactg accatgtgca
    27361 tcgctacgcg ttgttggtca cccgccagcg gcagaatggt tgggcgttcg gcacctggca
    27421 gcagggcgat gacttcatcc aggcgttcgg tcggtgcgtg catcatgatg tattttgatt
    27481 cgcgcgcctg gataacaccc tgaatacggg tcagcagttt gtcgatcagt tgctgtttag
    27541 attcttccat ttcgccatcg cgctggatca ggcaggcttt cgagcggtag ataacttcga
    27601 cttcgcgcag gccgttagct tccagcgtgg caccggtgga aaccagatca caaatcgcat
    27661 ctgccagtcc ggcacgcggg gcgacttcga cagaaccgtt cagtaagcag gatttaaaag
    27721 agatgccttt
//
