LOCUS       AB812028               20114 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli genes for O-antigen biosynthetic locus, partial
            sequence, strain: P9b.
ACCESSION   AB812028
VERSION     AB812028.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 20114)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..20114
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="P9b"
                     /db_xref="taxon:562"
                     /note="serogroup:O69"
     gene            <1..906
                     /gene="wcaM"
     CDS             <1..906
                     /gene="wcaM"
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis protein"
                     /protein_id="BAQ01159.1"
                     /translation="NYAILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDRDILI
                     SDHVIERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVE
                     NGKHFVIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVI
                     KGKYLSIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAASFVALTNIEMKRASLELHNK
                     PQHLFMRNIKVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNERGQSS
                     VDIDRINHHIVNVEKINFRLPERRE"
     gene            1069..1974
                     /gene="galF"
     CDS             1069..1974
                     /gene="galF"
                     /note="O069_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ01160.1"
                     /translation="MDEIMTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLELRVKRQLLAEVQSICPPGVT
                     IMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGR
                     YVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQA
                     FVKYGLRNLKEGAKFRKGIEKLLSE"
     gene            2346..3431
                     /gene="rmlB"
     CDS             2346..3431
                     /gene="rmlB"
                     /note="O069_02"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6 dehydratase"
                     /protein_id="BAQ01161.1"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLA
                     DVSDSERYVFEHADICDAAAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSALDGDKKNSFRFHHISTDEVYGDLPHPDEVNNKEQLPLFTETTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KALPIYGKGDQIRDWLYVEDHARALYIVVTEGKAGETYNIGGHNEKKNIDVVLTICDL
                     LDEIVPKEKSYREQITYVADRPGHDRRYAIDAEKISRELGWKPQETFESGIRKTVEWY
                     LSNTKWVDNVKSGAYQSWIEQNYEGRQ"
     gene            3431..4330
                     /gene="rmlD"
     CDS             3431..4330
                     /gene="rmlD"
                     /note="O069_03"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAQ01162.1"
                     /translation="MNILLFGKTGQVGWELQRALAPLGNLIALDVHSTDYCGDFSNPE
                     GVAETVKKIRPDVIVNAAAHTAVDKAESEPEFAQLLNATSVESIAKAANEVGAWVIHY
                     STDYVFPGTGEIPWQEADATAPLNVYGETKLAGEKALQEHCAKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKEREELAVINDQFGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAS
                     GTTTWHDYAALVFEEARKAGIPLALNKLNAVSTTAYPTPARRPHNSRLNTEKFQQNFA
                     LVLPDWQVGVKRMLNELFTTTAI"
     gene            4388..5266
                     /gene="rmlA"
     CDS             4388..5266
                     /gene="rmlA"
                     /note="O069_04"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="BAQ01163.1"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGG
                     DDCALVLGDNIFYGHDLPKLMDAAVNKESGATVFAYHVNDPERYGVVEFDKNGTAISL
                     EEKPLQPKSNYAVTGLYFYDNDVVEMAKNLKPSARGELEITDINRIYMEQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFINAEQVKILAEPL
                     KKNAYGQYLLKMIKGY"
     gene            5271..5816
                     /gene="rmlC"
     CDS             5271..5816
                     /gene="rmlC"
                     /note="O069_05"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="BAQ01164.1"
                     /translation="MNVIKTEIPDVLIFEPKVFGDERGFFFESFNQKVFEEAVGRKVE
                     FVQDNHSKSCKGVLRGLHYQLEPYAQGKLVRCVVGEVFDVAVDIRKSSPTFGKWVGVN
                     LSAENKRQLWIPEGFAHGFLVLSDEAEFVYKTNNYYYQKHERSILWNDKILNVEWPFT
                     SNLILSSKDMSASLFTVAEKF"
     CDS             5834..7189
                     /note="O069_06"
                     /gene="lar"
                     /codon_start=1
                     /transl_table=11
                     /product="putative coenzyme F420 hydrogenase/dehydrogenae
                     beta subunit"
                     /protein_id="BAQ01165.1"
                     /translation="MSIQNVIDNGYCVGCGACKLALGESVEIKMYEDGFYNASIKPNA
                     NIEIAEKICPFSDSSTNETILGASLYGDKKFDKRVGYFDDIYIGYVVDNQDRLTSSSG
                     GLTTWFAKKLLINKEVDAVIHVGHGTHMFDYIITENILDLDLQNNKKSRYYPVSFSEL
                     INKINQSDKKYLFIGIPCFVKSIRLAQKEGMVQNIKFVISLLCGHMKSKDFATSLAWQ
                     IGVKPDDLGSVDFRVKEDNKKANDYNIEVEDTCNKKYMHQSSSLFGTNWGLGFFKHHA
                     CDFCDDIAGELADATLGDAWLPKYINDSQGTNILIVRNDVLNKLLEQYQEEIVLETAN
                     VEDFYESQAGNFRNRREGLLVRVQNEKKWTPRKRLEIINSDIPLQRRKLYLVRQKLSE
                     QSIKKFQIAKKIGSIYSFKLLMVPDIFRYKMIEKNLISALKETIRIVAPRKLVKIFKK
                     R"
     gene            7194..8708
                     /gene="wzx"
     CDS             7194..8708
                     /gene="wzx"
                     /note="O069_07"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAQ01166.1"
                     /translation="MHRQVFRNVFLNVTTFLFNVVTGLYLTPFLIKYLGLEVYGILPL
                     ALFLTFYIGVITQALTASVNRFFIANLQTNNIKEANVVFNTAFCIIVTYSVLQFALLY
                     YPIQNIDQYFSIPTHSRDDARRLFESVLLSFSLALLTSIFSVSLFALNRLDLIQCVQL
                     IKIIIKFITIILFFEHHCIGIQFVGIAMILSELIALILTICLWRKLTPEINLKLFYFS
                     KKKVGELSKFAMWLIIDQVGYVLFIKMDLLLVNKFFGAKESGRYSIATQFSDLLRSFA
                     GLMAGVLAPVIMILHAKNELERIVTVTKTFVMILSLTIAIPISIICVFSQELIHFWLG
                     QDINIQTLIWIVTFPLIINLGVLPLFSINVAFKKVKLPSVLNIVLALVGVFVSIILIR
                     NTELGLLAVAAGFGFSLTLKNAVFIPIYAALNLRIDKLTFLTVHVRTILFTFFYVCFL
                     ILVKSKLSSNLYGFLAELTVLIIFGFIISIFFYSRDERKYITNTLSDKLKAKVK"
     CDS             8705..9838
                     /note="O069_08"
                     /gene="lat"
                     /codon_start=1
                     /transl_table=11
                     /product="putative pyruvyl transferase"
                     /protein_id="BAQ01167.1"
                     /translation="MKNKIGILNFQYSDHNYGAVLQAVALENVLKQLGKNAEHINFIP
                     KKKGNKNIKQFIIEFLASIGLKPFIYRVFNKKVIIKNKVEGSEIFEDFRNKYLNRTKA
                     FHSLNDLMELEDSYSSVIVGSDQVWRPKMYSDLTEIEIYFLSFISQKTKKISYAASFG
                     VERWEYDKNDNVTHKAQKYLNKFNSISVREKSGVDICNSVFDIRAEHVLDPTLLIGRD
                     FFDNLIKDKQPLVQKTISYYKLDLCESFLAGIEHLANLTGYETNNIYYKQLNNGSYEY
                     YPVLDWLSMINSSSIIITDSFHCVCFSILFNKSFYCCLNKERGASRLESLLNELGLQD
                     RLISEEELSRIYTIVDINYSPVEDILNKHRKQSIEFLVSAIDG"
     CDS             9843..10727
                     /note="O069_09"
                     /gene="wfgH"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01168.1"
                     /translation="MSHIIPVVIMTRNEGAYLLKCVQSIINTVTIPYHIYIIDNNSST
                     LEQEEVLKIIEYKFNDKVNIIRNRTNRWVLGLNKTLIELSKNKEQPYFFLTDGDIDFS
                     RCTAKPCWLSYLVTHMNSNVSLGKIGLSLNWDYISTTKELAAVYEQERSLYNESKKIN
                     DLYVSPVDTTAALFRWDWSIEGRPSLYPDHIRYLRPELYSCRTPLDINVEHMGWYKYC
                     AESGDTKNLEEKIVCFTMVGGDVKNEILDKVRFFYKVIYKSLSGPVKKAWYFRRYYYL
                     LKYFLFKGVRRFDGQNCL"
     gene            10756..11871
                     /gene="wzy"
     CDS             10756..11871
                     /gene="wzy"
                     /note="O069_10"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAQ01169.1"
                     /translation="MYIFRSEFVLAIFIFHLLFIILALYARKLDNKVLDYIFLILATT
                     LALIISLFRPGFGVDEPSYLEAFINFKNNADTFPFDYSFKVLYEILSNTGIQIEYFNN
                     TVSSLYIILLSITAIVTSSKNNKCFYFLMLLFSFTSLDLMFNAYRQAFAFIFIYNSLF
                     LFLREKKIKGALLAVISFGFHWSAVILILFYFLSRFLKNKYSYLILLLLFPFVLISMF
                     YPLGLMGIGYNVLLFLPLNELFKAHVLAYLEVDNISSASFYILNLFGRLPLAISVLTF
                     YAFILIFYKKIRMKRIIAMIVLMAVYCLVFMEMAYSFRNYYWVLPFFPIIALDYAESN
                     QAKIHSRMIGIAALHILIALPTFYSSGINSMIFNTGN"
     CDS             11891..12799
                     /note="O069_11"
                     /gene="wbbQ"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01170.1"
                     /translation="MCSLKVSALLVSYNPDINRLSEVLNSIHSQVDHLVLVDNGSKNK
                     NDILALIADYEGVYTLLNDNNIGLASAQNVGIDYIIDNNLSDFIVFFDQDSVLQSGFI
                     SALLETYTNLVTQNIKLAAVGPSFIDPVNNKQYPATVYAGPFIKRVDLERKPVEATFI
                     IASGCFVAIEALKKIGKMKDELFIDYIDVEWCLRARSLGYKIYISPKAVMKHTIGDNR
                     VSIFGRTISVHSPLRRYYLVRNSFYMIRLDYIPIGYKIREIFFNVVRICISLALSDDK
                     KKILHYTITAIKDGVSKKFGPCKKIL"
     CDS             12802..13950
                     /note="O069_12"
                     /gene="wdaW"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01171.1"
                     /translation="MIKIAHIQLLPMLSGVQRVCLDELSRLDKKKYQRYLICKEPGKL
                     SDEATAIGVQCIFLPELQRNISFKMDLIALYKLYRIIKIYKFDIVHTHSSKPGVLGRI
                     AARLNGVKLILHTVHGFSFPAAQNRFQYYIFWIMEKIGSICGDKLICLHKDDAVIAQE
                     KLFIHKNKISIIENGVDTNKFKKRNNNEIDKLSTYFNIDRNSDVVVGMIGRLWPQKNP
                     MLLLYAAKNIINNNKRVKFLFVGDGELKDSMNDYIIQNKLTQNITICGWCNDVSSYLN
                     IFDIFVLPSLWEGMPLAILEAESSSLPCIVSNIPGNRSIIRHTVDGYLFSLDNPSELE
                     SYINILIEDKERRIILGNNARVKILESYKIENRILKLDELYSSISLKE"
     CDS             13970..14995
                     /note="O069_13"
                     /gene="wceW"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyltransferase"
                     /protein_id="BAQ01172.1"
                     /translation="MRIKILDHMKGAAILAVVFIHSSGYLAVSNIGTFEWYIGIISRQ
                     FVNFAVPIFLFISGFLSFSRDIHDTPYYLKKKLLRIIIPYLSWSCFYFFLLFIFNNQS
                     FAVKNIIAQLILGTGIGVGYFVIVLVQFIMLTPLINAITSIKIHIMIICGFTIIGVGI
                     NYMSVKIDCLKLFSQFPYSAIPFFVWYPFYHLGFVFNKYNISCSKWSNSSILFWILSF
                     SLTLAISEGIFWGYTGNYSFAVSQLKLSSLVLSLCVCMVVYFYLNHDINYKYLSQLGT
                     MSYGIYLTHMLFVWFYHYLFSYTSVFIRHLVISCGFIFILSTISSVTLVFFIRKILGR
                     YSVYIVG"
     gene            15134..16540
                     /gene="gnd"
     CDS             15134..16540
                     /gene="gnd"
                     /note="O069_14"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ01173.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQGQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            16789..17955
                     /gene="ugd"
     CDS             16789..17955
                     /gene="ugd"
                     /note="O069_15"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ01174.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIATPTDYDPNTNYFNTSSVESVIK
                     DVVEINPYAVMVIKSTVPVGFTAAMHKKYRTKNIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPHVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            18045..19079
                     /gene="wzz"
     CDS             18045..19079
                     /gene="wzz"
                     /note="O069_16"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ01175.1"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLV
                     QLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGS
                     AVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQSLPLAVSYVGETP
                     EGAQKQLAKYIQQVDDQVNEELGKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQ
                     IQEALQYANQAQVTKPQVQQTEDVTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQT
                     RQNLLDIESLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLG
                     RNALRNYNAK"
     gene            complement(19176..19787)
                     /gene="hisI"
     CDS             complement(19176..19787)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ01176.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVNIAPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ"
BASE COUNT     5988 a   3538 c   4243 g   6345 t
ORIGIN
        1 aattacgcca tcttacgcca gggatttcat aaccagatta tcggtgccaa catcaccaac
       61 tgtaaattta gtgatttaca gggcgacgcc attgaatgga acgtggcgat taacgaccgt
      121 gatattttga tctccgacca tgtcatcgag cgcatcaact gtactaatgg caaaatcaac
      181 tggggcattg gcataggcct tgcggggagt acttatgata ataactaccc ggaagaccag
      241 gcagtgaaaa actttgtcgt ggcaaatatc acgggatcgg attgtcggca gttgatccat
      301 gttgaaaatg gcaaacattt tgttatccgt aatatcaaag cccgcaatat cacgccggat
      361 ttcagtaaga aagcaggcat agataacgcc acagtcgcta tttatggttg tgacaatttc
      421 gtgattgata atattgaaat gattaatagc gccgggatgt taatcggcta tggggtaatt
      481 aaaggcaaat atctctcgat accgcaaaat ttccgagtga ataatattca actggataac
      541 acccatcttg cttataaatt gcgcggcatc caaatctccg ccgggaatgc tgcctccttt
      601 gtggcactga ctaacattga gatgaagcgt gcctcgctgg agcttcacaa taaaccgcaa
      661 catcttttta tgcgtaatat caaagtgatg caggaatcct cagttggtcc cgcattgagc
      721 atgaacttcg acatgcgcaa agacgttcgc ggcgtcttta tggcgaaaaa agaaacactg
      781 ctgtctcttg caaatgttca tgcggtgaat gaaagagggc aaagctccgt cgatatcgac
      841 aggattaatc accatattgt taatgtggaa aagattaact ttagattgcc ggaacggagg
      901 gagtagattt gcgaccattc ctggaaaaat ggagccatac ttaggaacaa tgctactgca
      961 atccacaacg aagcggcgta acatcacaag taattcagta atcaattcag ggtaattgat
     1021 gctggcgaaa aaaatcgaac aagctataat tcagcaacca ttttacaggt ggatgaaata
     1081 atgacgaatt taaaagcagt tattcctgta gcgggtcttg ggatgcatat gttgcctgcc
     1141 actaaggcga ttcccaaaga gatgctaccg atcgtcgaca agccaatgat tcagtacatt
     1201 gttgacgaga ttgtggctgc aggtatcaaa gaaatcctcc tggtaactca cgcgtccaag
     1261 aacgcggtcg aaaaccactt cgacacctct tatgaattag aatctcttct tgaactgcgc
     1321 gtgaagcgtc aactactggc ggaagttcag tccatctgcc cgccgggcgt gaccattatg
     1381 aacgtacgtc agggcgaacc tttaggttta ggtcactcca ttttgtgtgc acgacccgcc
     1441 attggtgaca acccatttgt cgtggtgctg ccagacgttg tgatcgacga cgccagtgcc
     1501 gatccgctgc gttacaacct tgctgccatg attgcgcgtt tcaatgaaac gggccgtagc
     1561 caggtgctgg caaaacgtat gccgggtgac ctctctgaat actccgttat tcagaccaaa
     1621 gaaccactgg atcgtgaagg taaagtcagc cgcattgttg aatttatcga aaaaccggat
     1681 cagccgcaga cgctggactc agacatcatg gccgttggtc gctatgtgct ttctgcagat
     1741 atttggccgg aacttgaacg cactcagcca ggtgcatggg gacgtatcca actgacagat
     1801 gccattgccg aactggcgaa aaaacagtct gttgatgcaa tgctgatgac tggtgacagc
     1861 tacgactgcg gtaaaaaaat gggctatatg caggcatttg tgaagtatgg actacgcaac
     1921 ctgaaagaag gggcgaagtt ccgtaaaggt attgagaaac tgttaagcga ataatgaaaa
     1981 tctgaccgga tgtaacggtt gataagaaaa tcataacggc agtgaagatt cgtggcgaaa
     2041 gtaatttgtt gcgaatattc ctgccgttgt tttatataaa caatcagaat aacaacgagt
     2101 tagcaatagg attttagtca aagttttcca ggattttcct tgtttccagg gcggattggt
     2161 aagacaatta gcgtttgaat ttttcgggtt aagcgcgagt gggtaacgct cgctacatcg
     2221 taggcatgca tgcagtgctc tggtagctgt aaagccaggg gcggtagcgt gcattaatac
     2281 ctctattaat caaactaaga gccgctaatt tcacagcatg ctctgaagta atatggaata
     2341 aaaaagtgaa gatacttgtt actggtggcg caggatttat tggttctgca gtagttcgtc
     2401 acattataaa taatacgcag gatagtgttg ttaatgtcga taaattaacg tacgccggaa
     2461 acctggaatc acttgctgat gtttctgatt ctgaacgcta tgtttttgaa catgcggata
     2521 tttgcgatgc tgctgcaatg gcgcggattt ttgctcagca tcagccggat gcagtgatgc
     2581 acctggctgc tgaaagccat gtggatcgtt caattacagg ccctgcggca tttattgaaa
     2641 ccaatattgt tggtacttat gtccttttgg aagcggctcg caattactgg tctgctcttg
     2701 atggcgacaa gaaaaatagc ttccgttttc atcatatttc tactgacgaa gtctatggcg
     2761 atctgcctca tcctgacgaa gtaaataata aagaacaatt acccctcttt actgagacga
     2821 cagcttacgc gcctagtagt ccttattccg catcaaaagc atccagcgat catttagtcc
     2881 gtgcgtggaa acgtacctat ggtttaccga ccattgtgac taactgttcg aataactacg
     2941 gtccttatca ctttccggaa aaattgattc cactagtaat tcttaatgct ctggaaggta
     3001 aggcattacc tatttatggc aaaggggatc aaattcgtga ctggctgtat gttgaagatc
     3061 atgcgcgtgc gttatatatc gtcgtaaccg aaggtaaagc gggtgaaact tataacattg
     3121 gtggacacaa cgaaaagaaa aacatcgatg tagtgctcac tatttgtgat ttgttggatg
     3181 agattgtacc gaaagagaaa tcttaccgtg agcaaattac ttatgttgcc gatcgcccgg
     3241 gacacgatcg ccgttatgcg attgatgcag agaagattag ccgcgaattg ggctggaaac
     3301 cgcaggaaac gtttgagagc gggattcgta aaacggtgga atggtacctg tccaatacaa
     3361 aatgggttga taatgtgaaa agtggtgctt atcaatcgtg gattgaacag aactatgagg
     3421 gccgccagta atgaatattc tccttttcgg caaaacaggg caggtcggtt gggaactaca
     3481 gcgtgctctg gcacctttgg gtaatttgat tgctcttgat gttcactcca ctgattattg
     3541 tggtgatttt agtaatcctg aaggtgtagc tgaaaccgtc aaaaaaattc gccctgatgt
     3601 tattgttaat gctgcggctc ataccgcagt agataaggct gagtcagaac ccgaatttgc
     3661 acaattactc aatgcgacca gcgttgaatc aattgcaaaa gcggctaatg aagttggggc
     3721 ctgggtaatt cattactcaa ctgactacgt atttccgggg accggtgaaa taccatggca
     3781 ggaggcggat gcaaccgcac cgctaaatgt ttacggtgaa accaagttag ctggagaaaa
     3841 agcattacaa gagcattgtg cgaagcacct aattttccgt accagctggg tctatgcagg
     3901 taaaggaaat aacttcgcca aaacgatgtt gcgtctggca aaagagcgtg aagaattagc
     3961 cgttattaat gatcagtttg gtgcgccaac aggtgctgaa ctgctggctg attgtacggc
     4021 acatgcaatt cgtgtggcac tgaataaacc agaagtcgca ggcttgtacc atctggtagc
     4081 cagtggtacc acaacctggc acgattatgc tgcgctggtt tttgaagagg cgcgcaaagc
     4141 aggcattccc cttgcactca acaagctcaa cgcagtatca acaacagcct atcctacacc
     4201 agctcgtcgt ccgcataact ctcgccttaa tacagaaaaa tttcagcaga actttgcgct
     4261 tgttttgcct gactggcagg ttggtgtgaa acgcatgctc aacgaattat ttacgactac
     4321 agcaatttaa tagtttttgt atcttgttcg tgatggtgga acaagataaa ttaaaaggaa
     4381 tgatggaatg aaaacgcgta aaggtattat tttagcgggt ggttctggta cacgtcttta
     4441 tcctgtgact atggctgtca gtaaacagct attacctatt tatgataaac cgatgatcta
     4501 ttatccgctc tctacactga tgttggcggg tattcgcgat attctaatta taagtacgcc
     4561 acaggatact cctcgttttc aacaactgtt gggtgacggg agccagtggg gcctgaatct
     4621 tcagtacaaa gtgcaaccaa gtccagatgg tcttgcgcaa gcatttatca tcggtgaaga
     4681 atttatcggt ggtgatgatt gtgctttggt tcttggtgat aatatttttt acggtcacga
     4741 tctgccgaag ttaatggatg ccgctgttaa caaagaaagt ggtgcaacgg tgtttgccta
     4801 tcacgttaat gatcctgaac gctatggtgt cgttgagttt gataaaaacg gtacggcaat
     4861 tagcctggaa gaaaaaccgc tacagccaaa aagtaattat gcggtaactg ggctttattt
     4921 ctatgataac gacgttgtag aaatggcgaa aaatcttaag ccttctgccc gcggtgaact
     4981 ggaaattacc gatattaacc gtatctacat ggaacaaggg cgtttatctg ttgccatgat
     5041 gggacgtgga tatgcatggt tagacacggg gacacatcaa agcctgattg aggcaagcaa
     5101 cttcattgct acaattgaag agcgtcaagg gttgaaagtt tcctgtccag aagaaattgc
     5161 ttaccgtaaa gggtttatca atgctgagca ggtgaaaata ttagctgaac cgttgaagaa
     5221 aaatgcttat ggtcagtacc tgctaaaaat gattaaaggt tattaataaa atgaacgtaa
     5281 ttaaaacaga gattccagac gtattaattt tcgaaccgaa agtttttggt gacgagcgcg
     5341 gtttcttttt cgagagcttt aaccagaagg tttttgagga agctgtaggc cgcaaagttg
     5401 aatttgtcca ggataaccat tcgaagtctt gtaaaggtgt tttacgcgga ctgcattatc
     5461 agttagaacc ttatgcacaa ggaaagttgg tgcgctgcgt tgttggtgaa gtttttgacg
     5521 tagctgttga tattcgtaaa tcgtcgccta cctttggtaa atgggttggg gtgaatttat
     5581 ctgctgagaa taagcggcaa ttgtggatcc ctgagggatt tgcgcatggg tttttggtgc
     5641 tgagcgacga ggcagaattt gtttataaga caaacaatta ttattatcaa aagcatgaaa
     5701 gaagcattct ttggaacgat aaaattctca acgtagaatg gccatttact tctaacttaa
     5761 ttctttcttc aaaagatatg agcgcgtcat tattcactgt tgcagaaaaa ttttaattgg
     5821 ttttggaaat aaaatgtcta tacaaaatgt aatagataat ggttactgcg tcggatgtgg
     5881 tgcttgtaaa ttggctcttg gagagtcagt ggaaataaaa atgtatgaag atggctttta
     5941 taatgcttcg ataaaaccta atgcaaatat tgaaattgcc gagaaaattt gtccattttc
     6001 tgatagttca acaaatgaaa ctatcttagg cgcatcactt tatggagata aaaaatttga
     6061 caagcgtgta ggatattttg acgacattta tattgggtat gtagttgata atcaggaccg
     6121 actaacttcc agttcaggtg gacttactac ctggtttgct aaaaagttat taataaataa
     6181 agaggttgat gcggtaattc atgtagggca tgggacgcat atgtttgact acattattac
     6241 tgagaatatt ttagatcttg atttacagaa taataaaaaa tccagatatt atcctgtaag
     6301 tttttctgaa ttgataaata aaataaacca atcagataaa aaataccttt tcattggcat
     6361 tccatgtttt gttaaatcaa taagattagc gcagaaagaa ggaatggttc agaatattaa
     6421 atttgtgatt tcattactct gcggacatat gaagtccaaa gatttcgcta cgagtcttgc
     6481 gtggcagatt ggcgttaaac ctgatgatct gggtagtgta gactttcgtg tcaaggagga
     6541 taataaaaaa gcaaatgatt ataatataga agttgaagat acttgtaata agaaatatat
     6601 gcatcaaagc tcttcgttgt ttggcactaa ttgggggcta ggctttttca aacatcatgc
     6661 atgtgatttt tgtgatgaca ttgcaggtga attggcggat gcaactttag gtgatgcttg
     6721 gttaccgaag tatataaatg attcacaagg tactaatata cttattgtaa gaaacgatgt
     6781 tttaaataaa ttacttgaac aatatcaaga agaaatagtg cttgaaactg cgaatgtcga
     6841 ggatttttat gaaagtcaag ctgggaattt tcgtaatcga cgtgaagggt tacttgttcg
     6901 tgtccaaaat gaaaaaaaat ggactcctag aaaaaggttg gaaattatta actccgatat
     6961 tccattacaa cgtcgtaaat tgtatttagt tcgtcagaag ttaagtgaac aaagtataaa
     7021 gaaatttcaa atagctaaaa agataggttc aatatattca ttcaaattgt taatggttcc
     7081 tgatattttt agatataaaa tgattgagaa gaatttaata tcggcgttaa aagaaactat
     7141 aagaatagtg gcgccaagaa aacttgtaaa aatattcaaa aaacggtagc tttatgcata
     7201 ggcaagtttt tcgaaacgta tttctaaatg tgacgacatt tttatttaat gtagttactg
     7261 gattatattt aactccattt ttgattaaat atttagggtt ggaagtgtat ggtatacttc
     7321 ctttagcatt gtttttaacc ttttatattg gcgtgataac tcaggccctt acggcatcag
     7381 taaatcgatt ttttattgca aatttacaaa ctaataacat taaagaggct aatgttgttt
     7441 ttaacactgc tttttgtatc atagttacat attcggtatt gcagtttgct ctcctatact
     7501 atcctataca aaatatagac cagtattttt ctataccgac gcatagcaga gatgatgccc
     7561 ggagattgtt tgaatcagtt ttactcagtt tctctcttgc gcttttaaca tccattttta
     7621 gtgtttcgct ttttgcatta aacaggttgg atttgattca atgcgtccag ttaatcaaaa
     7681 ttattataaa gttcattacc ataatattat tctttgaaca tcattgcata ggtatccagt
     7741 ttgtaggaat agcaatgatt ctgtcagagt taatagcttt aattttgacg atttgtttat
     7801 ggagaaaatt gacaccggaa ataaatttaa aactatttta cttcagtaaa aagaaagtag
     7861 gagagctttc aaagtttgca atgtggttga ttattgatca ggttggatat gttcttttta
     7921 ttaaaatgga tttattattg gtaaacaaat tctttggggc gaaggaatct gggcgctatt
     7981 caattgcaac gcaatttagt gatttactaa gatcatttgc agggcttatg gcgggagttc
     8041 ttgcacctgt aataatgata ctacacgcca agaatgaatt agaaagaatt gtaaccgtta
     8101 ccaaaacgtt tgtgatgatt ctatcgctga caatagcgat accaatttct ataatctgtg
     8161 tattttctca agagctgatt catttctggc taggacaaga tataaatatc caaactttaa
     8221 tttggattgt gacttttcca ttaataatta atttgggcgt cttaccatta ttttctataa
     8281 atgtagcgtt taaaaaagtt aaactaccta gtgttctaaa tatcgtattg gcactagttg
     8341 gcgtatttgt ctcaattata cttattcgaa atactgaact gggtttactt gcagtagcgg
     8401 ctgggtttgg tttttccctg accctcaaaa atgcggtatt tatacctatt tacgcggcac
     8461 taaatttaag aatagataaa ttaacatttc taactgtaca tgtaagaact attttattta
     8521 cattttttta tgtatgtttt ctgattttag ttaagtcaaa actgtctagt aatctttacg
     8581 ggtttttagc tgaattaaca gtgcttatta tatttggctt tataattagt atcttttttt
     8641 attctcggga tgaaaggaag tatattacta atacactttc agataaatta aaagcgaagg
     8701 taaaatgaaa aataaaattg gtattctaaa ttttcaatat tcggatcata attatggtgc
     8761 agtcttacaa gctgttgcac tagaaaatgt tttaaaacag ctagggaaaa atgctgaaca
     8821 tattaatttt attccaaaga agaaaggtaa caaaaatatc aaacaattta taattgaatt
     8881 tttagcttct attggtttaa aacctttcat ttatcgggta tttaacaaaa aagttattat
     8941 aaaaaataaa gttgaaggat ctgagatttt tgaggatttc aggaataaat atttgaacag
     9001 aacaaaagcg tttcattccc tcaatgacct tatggaatta gaggatagtt acagttctgt
     9061 tatcgttgga agtgatcaag tctggcgccc caaaatgtac tcagacctta cagaaattga
     9121 aatttatttc ctttctttta tttcacagaa aacaaaaaaa atttcttatg cagcaagttt
     9181 tggtgttgag cgatgggaat atgacaaaaa tgataatgtg acacataaag cacaaaaata
     9241 tctgaacaaa tttaattcta tttctgttag agaaaaatca ggagtagaca tttgtaatag
     9301 tgtatttgat attagagctg agcatgttct ggatccaaca ctattgatcg gacgtgattt
     9361 tttcgacaat cttattaaag acaaacaacc attagttcaa aagacaataa gttattataa
     9421 gttagatctt tgtgagtctt ttttagcggg aatagagcat cttgctaatc taaccggcta
     9481 tgagactaat aatatttact acaaacaact gaataatggg agttatgaat attatccagt
     9541 tttagattgg ctaagcatga ttaattcatc ttcgataata ataacagact cttttcattg
     9601 tgtatgcttc tcaattttat ttaataaaag cttctattgt tgtcttaata aagaaagagg
     9661 agcatcgagg cttgaaagtt tattgaatga actggggttg caagacagat taatctctga
     9721 agaagaacta tcgagaattt atacaatagt tgatatcaat tattctcctg tagaagatat
     9781 tttgaataag cacaggaaac agtcaataga atttttagtt tcagcaattg atggataatt
     9841 aaatgagtca tataattcca gtagttatta tgacacggaa tgaaggtgct taccttttga
     9901 aatgtgtcca atcaatcatt aatactgtta ctatacccta tcatatatat attattgata
     9961 acaattcttc aacattggag caagaagaag ttctaaaaat tattgaatat aagtttaatg
    10021 ataaagtaaa tattattaga aatcgtacta acaggtgggt tctgggttta aataagacac
    10081 ttattgaatt gagtaaaaat aaagaacaac cctatttctt tttaactgat ggtgatattg
    10141 acttttcaag atgcaccgct aagccatgtt ggttatcata tttggttacc catatgaatt
    10201 ctaatgtatc tctggggaaa attggcttat ctctcaattg ggattacatt tcaactacaa
    10261 aagaattggc ggctgtttat gaacaggaga gaagtctata taatgaaagt aaaaaaataa
    10321 atgatttata tgtgtctcct gttgatacaa cagcggcatt atttcgatgg gattggtcta
    10381 tagaaggaag accaagctta tatccagacc atattagata ccttagacca gaactttatt
    10441 catgtcgaac accattagat attaatgtag agcatatggg atggtataaa tattgtgcag
    10501 aatctggaga tacaaaaaat ttagaggaaa aaatagtctg cttcactatg gttggtggtg
    10561 atgttaaaaa cgaaatttta gataaggttc gttttttcta taaggttata tataaatcat
    10621 tgtctggtcc agtaaaaaaa gcatggtatt tcaggagata ttattatctt ttgaaatatt
    10681 ttctttttaa gggcgttcgc agattcgatg gtcaaaactg tctttgaaat gtaatgtaat
    10741 tattggagtg taactttgta tatatttcga agtgagtttg tactagcgat atttattttt
    10801 catttgttat tcataatatt ggccttatat gcacgaaaac ttgataataa ggtattagat
    10861 tatatatttc ttatattggc aactacatta gccttaatta tttcactctt tagacctggc
    10921 tttggagttg atgaaccttc ttatcttgag gcatttatta atttcaaaaa taatgctgac
    10981 acatttccat tcgattattc atttaaagta ttatatgaaa tattatctaa tacgggcata
    11041 caaattgagt atttcaataa cacagtcagc tctttatata ttattttact tagtataacg
    11101 gcgatagtaa catcgagtaa aaataataag tgtttttatt tcttgatgtt attgttcagt
    11161 tttacttcat tagatctaat gtttaatgct tacaggcaag catttgcatt tatatttatt
    11221 tataactctt tatttctttt tttgagagaa aagaaaatca agggggcttt attagctgta
    11281 atctcttttg ggtttcattg gtcagcagtt atcctgatct tattttattt tttatcgagg
    11341 tttcttaaga ataaatattc ttaccttatt ttacttttat tatttccatt tgtattaatc
    11401 tcgatgtttt atccattagg tttgatgggg ataggatata atgtgttgtt atttcttcct
    11461 ttgaatgaat tattcaaagc tcatgtgtta gcgtatttag aagttgataa catttctagc
    11521 gcgtcgtttt atatacttaa tctctttggt cgactaccat tggctatatc ggtattaact
    11581 ttttatgctt ttatactgat tttttacaaa aaaataagaa tgaagcgtat aatagcaatg
    11641 attgtcttga tggctgttta ttgtctagtg tttatggaga tggcatatag ttttagaaat
    11701 tattattggg ttctaccatt tttccctatt attgctttag attacgcaga atctaatcaa
    11761 gcgaaaattc attcaagaat gataggcatt gctgctcttc atatcttgat agcattgcct
    11821 actttttaca gttcaggtat aaactctatg attttcaata ctggcaatta gtattgaata
    11881 tggaaaaaaa atgtgttcat taaaagttag cgctttactc gttagttaca atccagatat
    11941 taatagatta agtgaggttc ttaatagtat tcattctcaa gtagatcatc tagttttagt
    12001 tgataatggt tcaaaaaata aaaatgatat acttgctctc attgccgatt atgagggggt
    12061 ttatacactg cttaatgata ataatatagg tttagcctct gctcaaaatg ttggtattga
    12121 ttatattatt gacaataacc tttccgattt tatcgtgttc ttcgaccaag atagtgtatt
    12181 gcagtcaggt tttattagtg cgctactcga aacgtatact aatttagtaa ctcagaatat
    12241 taaattagca gcagtaggac catcatttat tgatcctgta aataataaac aatatcctgc
    12301 gactgtttat gcaggaccat ttattaaacg agtagatctt gaaagaaaac ctgtagaagc
    12361 taccttcata attgcttctg gatgctttgt tgccattgag gcattgaaaa aaattgggaa
    12421 aatgaaggat gaattgttta tagactatat cgatgttgaa tggtgtctca gagctaggag
    12481 tttaggatac aaaatatata tttcacctaa agctgtaatg aaacatacta ttggagataa
    12541 tcgagtatct atctttgggc gaacaatatc tgttcattca ccattacgtc gatattatct
    12601 tgtaaggaat agcttttata tgattagatt ggattatata ccaattggat ataaaattag
    12661 agaaatattt tttaatgtag ttcgtatttg tatcagctta gctctatctg atgataaaaa
    12721 aaagatactt cattatacaa taactgcaat taaagatggt gttagtaaaa aattcggacc
    12781 ttgtaaaaaa atactctaat tatgatcaaa atagctcata ttcaattatt gccaatgctt
    12841 agtggtgttc agagagtgtg tttggatgag ctctcaagat tggacaaaaa aaaatatcaa
    12901 agatacttaa tttgtaaaga accaggtaaa ctcagtgatg aggctactgc tattggcgtt
    12961 caatgtatct ttcttcccga gcttcagcgc aatatcagct ttaagatgga cttaatagcg
    13021 ttgtacaaat tatatcggat aataaagata tataaattcg atattgttca tacacactct
    13081 tctaagccag gtgttttagg gcgtattgca gccaggctga atggtgttaa actgatactt
    13141 cacactgtgc acggtttttc ttttcctgct gcacaaaata ggttccaata ttatatattt
    13201 tggatcatgg aaaaaattgg ctcaatatgt ggagataaat taatatgtct gcataaagat
    13261 gatgcagtga ttgctcagga aaaattattt attcataaga ataaaatttc cataattgaa
    13321 aatggcgtcg acactaacaa attcaagaag agaaataata atgaaataga taaattatct
    13381 acatatttta acatagatag aaattcggat gttgtggtcg ggatgatagg tagactgtgg
    13441 ccacaaaaaa accccatgct tttattatat gcagcaaaaa atataatcaa caataataaa
    13501 agagtaaaat tcttgtttgt cggcgatggt gagttaaaag actcaatgaa cgattatatt
    13561 attcaaaata aacttaccca gaatattacc atttgtggct ggtgtaatga tgttagttct
    13621 tatttgaata tatttgatat ttttgtatta ccatctttat gggagggtat gcctttggca
    13681 attttagaag ccgaaagtag ttcgttgccc tgtattgttt caaatatccc gggaaacagg
    13741 agtataatca ggcatacagt tgatggctat ctcttttcat tagataaccc atctgaactt
    13801 gaatcttaca ttaatatatt aattgaggat aaagaaagac gtattatctt gggtaataac
    13861 gccagagtca aaattcttga aagctataaa atagaaaata ggattttgaa attagatgaa
    13921 ctgtatagtt caatttcttt aaaagaatag cgttgtatgt tgaggggata tgcggataaa
    13981 aatactcgac catatgaaag gtgctgctat tttagctgtg gtatttattc attcttcagg
    14041 ttatcttgct gtttctaata taggaacatt tgaatggtac atcggtataa tatcgcggca
    14101 atttgttaat tttgcagtgc ctattttttt atttatatct ggttttttat ctttttctcg
    14161 agatatacat gatacaccat actatctcaa gaaaaaatta ttaagaatta ttatacctta
    14221 tctctcatgg tcttgttttt acttctttct tttattcata tttaataacc aaagtttcgc
    14281 tgtcaaaaat attatagctc agttgattct tggtacggga ataggtgtgg gatattttgt
    14341 gatcgtttta gtgcaattta ttatgctgac accgttaatt aatgcgatta catctataaa
    14401 aatacatatt atgattatat gtggttttac tatcataggt gtggggatta attatatgtc
    14461 tgtgaagatt gattgcttga aactgttttc acagtttcct tattccgcca ttcctttttt
    14521 tgtatggtat cctttttatc atttgggctt tgttttcaat aagtataata tatcttgttc
    14581 aaagtggtct aatagttcca tcttattttg gattttatct ttttcactta cattagccat
    14641 ttctgaaggg atattttggg gttatactgg gaactattca tttgctgtgt ctcaacttaa
    14701 actatcatct ttggttctct ctttatgcgt ttgtatggtt gtttattttt atctaaacca
    14761 tgatataaat tataaatacc tttctcaatt agggacaatg tcctacggga tttatcttac
    14821 tcatatgttg tttgtttggt tctatcatta tctcttttcg tatacgagtg tgtttataag
    14881 gcatttagtt atctcgtgtg gctttatctt tatattaagt acaatatcat cagttacctt
    14941 agtttttttt ataagaaaaa ttttggggag atattccgta tatattgtag ggtaggtgat
    15001 tgcttgatat ttatactgtt ttaagaagaa gcctaattta tctcaatact gggcatttca
    15061 ctagagctgt attagtatat ttgtcacatt ctcatccgta tttctaatgt atttttcaga
    15121 gcaggagact taaatgtcaa agcaacagat cggcgtcgtc ggtatggcag tgatggggcg
    15181 caaccttgcg ctcaacatcg aaagccgtgg ttataccgtc tctattttca accgttcccg
    15241 tgaaaaaacg gaagaagtga ttgccgaaaa tccaggcaag aaactagttc cttactatac
    15301 ggtgaaagag tttgttgaat ctctggaaac gcctcgtcgc atcctgttaa tggtgaaagc
    15361 aggtgcaggc acggatgctg ctattgattc cctcaaacca tatctcgata aaggcgacat
    15421 catcattgat ggtggtaata ccttcttcca ggacaccatt cgtcgtaatc gtgagctttc
    15481 tgcagaaggt tttaacttca ttggtaccgg tgtttccggc ggtgaagaag gtgcgctgaa
    15541 aggtccttcc attatgcctg gtgggcagaa agaagcctat gaacttgttg cgccgatcct
    15601 gaccaaaatc gccgcagtgg ctgaagacgg ggagccatgc gttacctata ttggtgccga
    15661 tggtgcaggt cactatgtga agatggttca caacggtatt gaatacggtg atatgcagct
    15721 gattgctgaa gcctattctc tcctgaaagg cggcctgaat ctctctaacg aagaactggc
    15781 acagaccttt accgagtgga ataacggtga actgagtagc tacctgatcg acatcaccaa
    15841 agatatcttc accaaaaaag atgaagacgg taactacctg gttgatgtga ttctggatga
    15901 agccgctaac aaaggtaccg gtaaatggac cagccaaagt gcgctggatc tcggcgaacc
    15961 gctgtcgctg attaccgagt ctgtgtttgc acgttatata tcttctttga aagatcagcg
    16021 tgttgccgcc tctaaagtac tgtctggtcc gcaaggacag ccagcaggcg acaaagctga
    16081 gttcattgaa aaagttcgcc gtgcgctgta tttgggcaaa atcgtttctt acgcccaggg
    16141 cttctctcag ctgcgtgcgg cgtctgaaga gtacaactgg gatctgaact acggcgaaat
    16201 cgcgaaaatt ttccgtgctg gctgtattat ccgtgcgcag ttcctgcaga aaatcaccga
    16261 tgcttatgcc gaaaatccgc agatcgctaa cctgctgctg gctccgtact tcaagcaaat
    16321 tgccgatgac taccagcagg cgctgcgtga tgtcgttgct tatgcagtac agaacggtat
    16381 cccggttccg accttcgccg ctgcggttgc ctattatgac agctaccgtg ccgctgttct
    16441 gcctgcgaac ctgatccagg ctcagcgtga ctattttggt gcgcatactt ataagcgcat
    16501 tgataaagaa ggtgtgttcc atactgaatg gctggattaa tctgatttaa ccaacaataa
    16561 attgaggccc ggcgtatatt acgccgggct ttttttttgc caattatctt atagactaaa
    16621 tttcactgct taatattaac ttaataaata tcagctattc ttataaagaa aatctgaatt
    16681 gtttttcgtt gcgttgacca tcgaacaacg tagcgttaaa acttttagct cttatcagga
    16741 tgctaaaaac atcatgattc acagttaagt taattctgag agcatgaaat gaaaatcacc
    16801 atttccggta ccggctatgt aggcttgtca aacgggcttc taatcgcaca aaatcatgag
    16861 gttgtggcat tagatatttt accgtcacgc gttgctatgc tgaatgatcg gatatctcct
    16921 attgttgata aggaaattca gcagtttttg caatcagata aaatacactt taatgccaca
    16981 ttagataaaa atgaagccta ccgggatgct gattatgtca tcatcgccac tccaaccgac
    17041 tatgatccta acactaatta tttcaataca tcgagtgtag aatcagtaat taaggacgta
    17101 gtagagataa atccttatgc ggttatggtc atcaaatcaa cggtacccgt tggctttacc
    17161 gcagcgatgc ataagaaata tcgtactaaa aatattattt tctctccgga atttctccgt
    17221 gagggtaaag ccctttacga taatctccat ccttcacgta ttgtcatcgg tgagcgttca
    17281 gaacgcgcag aacgttttgc tgctctgtta caggaaggcg cgattaagca aaatatcccg
    17341 accctgttta ccgactcaac cgaagcagaa gcgattaaac ttttcgctaa tacctatctg
    17401 gcgatgcgcg tagcgtactt taatgaactg gatagctacg cagaaagttt aggtctgaat
    17461 actcgccaga ttatcgaagg cgtttgtctc gatccgcgta ttggcaacca ttacaacaat
    17521 ccgtcgtttg gttatggtgg ttattgtctg ccgaaagata ccaagcagtt actggcgaac
    17581 tatcagtctg tgccgaataa cctgatctcg gcaattgtcg atgcaaaccg cacgcgtaaa
    17641 gattttattg ccgatgccat tttgtcacgc aaaccgcatg tggtgggtat ttatcgcctg
    17701 attatgaaga gcggttcaga taacttccgt gcgtcttcta ttcaggggat tatgaagcgt
    17761 atcaaggcga aaggtgttga agtaatcatc tacgagccag tgatgaaaga agactcattc
    17821 ttcaactctc ggctggaacg tgatctcgcc actttcaaac aacaagccga cgtaattatc
    17881 tccaaccgta tggcagaaga gcttaaggat gtggcagaca aagtctacac ccgcgatctc
    17941 tttggcagtg actaacatcc tgttatcagg gcgattttcg ccctgattct cttatgttcc
    18001 ctttgtaata attcattatt tttatcattt atcctatagc attcatggcg attatcgcta
    18061 aactatggcg acttaaaatt atttcgtccg ttagggtaat gatgagagta gaaaataata
    18121 atgtttctgg gcaaaaccat gacccggaac agattgattt gattgattta ctggtgcagt
    18181 tgtggcgtgg caagatgaca attatcatct ctgtcattgt tgctattgcc ctggctatag
    18241 ggtatctggc cgttgccaaa gaaaagtgga cttccacagc tatcgttact caacctgatg
    18301 tggggcaaat cgctggttat accaacgcga tgaatgtgat ctacggatcg gctgtaccga
    18361 aagtctccga cattcaggct tcacttatcg gacgttacag cactgcattc tcagcattag
    18421 cggaaacgct ggataaccag gaagaagcag aaaagctgac cattgagcct accgtcaaaa
    18481 atcagtcatt acctttagcg gtgtcttatg ttggtgaaac acctgaaggt gctcagaagc
    18541 agctggcgaa gtatatccag caagttgacg accaggtaaa tgaagaactg ggaaaagacc
    18601 tgaaagacaa catcgcgctg cgtatgaaaa acttgcagga ttctctgaaa actcaggaag
    18661 tagttgcgca ggagcagaaa gatctgcgta tccgtcagat tcaggaagcg ttgcagtatg
    18721 cgaatcaggc gcaggtgaca aagccacagg ttcagcagac tgaagatgtg acacaagata
    18781 cgttgttcct tttggggagc gaagcgctgg agtcgatgat taagcatgaa gcgactcgtc
    18841 cgttggtgtt ctcaccaaac tactatcaga cacgtcaaaa cctgctggat atcgaaagct
    18901 taaaagttga tgatcttgat attcatgctt accgctatgt gatgaaaccg acgttaccta
    18961 ttcgtcgcga tagcccgaaa aaggcaatca ctttgattct ggcggtgctg ctgggcggca
    19021 tggttggcgc ggggattgtg ctggggcgta acgctctgcg taattacaac gcgaagtaat
    19081 ctttttggtt ttaaagaaaa cgggcagggt ggtgacacct tgcccgtttt ttttgccgga
    19141 tgcgacaaca acatcgcatc cgcttacccc gcaactcact gatgccgttt acgcaggttc
    19201 tcaatcaccg ttgttaaatc cagatcctga tcctgcaaca acaccaacag gtgatacatc
    19261 aagtcagacg cctcgttggt gagttcaaag cggtcatgta ccgttgctgc tagtgcggtt
    19321 tccacgccct cttcgcccac tttctgtgca atgcgtttgg tgccgctggc atacagtttg
    19381 gctgtgtaag aggtttccgg atcggcagat ttgcgttcgg cgagcaattg ttccagttga
    19441 tacaggaaca gccactggtg agcggtgtcg ccgaagcagc tgctggtgcc tttgtggcag
    19501 gttggcccga tgggattcgc cagtaccagt agcgtgtcgt tgtcgcagtc cggcgcaata
    19561 tttactacgt tgaggaaatt gcccgacgtt tcgcctttgg tccacagtcg ctgtttagtg
    19621 cgcgagaaga aagtgacttt gccgctttcg atggttttgt ctaaggcttc cgggttcata
    19681 tagcccagca ttagcacttc gccagatacc gcgtgttgca caatcaccgg catcagtccg
    19741 tcggtttttt cccagtccag ttcgcgacgt tgttgttctg ttaacatatc ctgatctcca
    19801 cgccctgtgt tgccaggtac gcttttaatt caccaatatt gattatttgt ttgtggaata
    19861 cggaagccgc cagcgcgccg tcaacgtcgg catcacggaa ggcttcgagg aagtgttcca
    19921 tggtgcccgc gccaccggag gcaatcagcg ggacgcggca aacttctcgc acttttttca
    19981 gctgctcgag gtcgtaaccg ttacgcacgc cgtcctgatt catcatgttg aggacgattt
    20041 ctccggcacc gcgtttttgc acttcctgta cccagtcgag tgtttcccac tgagtgacgc
    20101 gggtgcggct ttca
//
