LOCUS       AB812037               21331 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli genes for O-antigen biosynthetic locus, partial
            sequence, strain: H53.
ACCESSION   AB812037
VERSION     AB812037.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 21331)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..21331
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="H53"
                     /db_xref="taxon:562"
                     /note="serogroup:O88"
     gene            <1..910
                     /gene="wcaM"
     CDS             <1..910
                     /gene="wcaM"
                     /codon_start=2
                     /transl_table=11
                     /product="colanic acid biosynthesis protein"
                     /protein_id="BAQ01306.1"
                     /translation="ANYAILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDSDIL
                     ISDHVIERINCTNGKINWGIGIGLAGSTYDNNYPEDQSVKNFVVANITGSDCRQLIHV
                     ENGKHFVIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGV
                     IKGKYLSIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHN
                     KPQHLFMRNIKVMQESSVGPALIMNFDMRKDVRGVFMAKKETLLSLANVHAVNEKGQS
                     SVDIDRVNHHIINMEKINFRLPERRE"
     gene            1073..1978
                     /gene="galF"
     CDS             1073..1978
                     /gene="galF"
                     /note="O088_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ01307.1"
                     /translation="MDEIMTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVT
                     IMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNE
                     TGRSQVLAKRMAGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGR
                     YMLSADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQA
                     FVKYGLRNLKEGAKFRKGIEKLLSE"
     CDS             2504..3640
                     /note="O088_02"
                     /gene="ISAs1"
                     /codon_start=1
                     /transl_table=11
                     /product="trasnposase od ISEc1"
                     /protein_id="BAQ01308.1"
                     /translation="MELKKLMEHISIIPDYRQAWKVEHKLSDILLLTICAVISGAEGW
                     EDIEDFGETHLDFLKQYGDFENGIPVHDTIARVVSCISPAKFHECFINWMRDCHSSDD
                     KDFIAIDGKTLRHSYYKSRRRGAIHVISAFSTMHSLVIGQIKTDEKSNEITAIPELLN
                     MLDIKGKIITTDAMGCQKDIAEKIQKQGGDYLFAVKGNQGRLNKAFEEKFPLKELNNP
                     EHDSYAISEKRHGREEIRLHIVCDVPDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKE
                     PEMTVRYYISSADLTAEKFATAIRNHWHVENKLHWRLDVVMNEDDCKIRRGNAAELFS
                     GIRHIAINILTNDKVFKAGLRRKMRKAAMDRNYLASVLAGSGLS"
     CDS             3677..4297
                     /note="O088_03"
                     /gene="werO"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyltransferase"
                     /protein_id="BAQ01309.1"
                     /translation="MILQRVGDDMKQALSRMKIKLLSYFYKRKNRSTQFGRYTVLFCR
                     ANITNSIVGDYTYFAGTASVNNCEIGKFCSIAEGVKIGLGKHPVDFLSTHPVFYSENT
                     CFPYRLKNYRVNEKVIESITESERVIIGNDVWIGVNAIVMDGVTIGDGAVIGAGAVVT
                     KDVQPYTIVGGVPARVIRTRQNINCSWWEFDVDTLVDFSSNFKKRL"
     CDS             4297..4881
                     /note="O088_04"
                     /gene="werP"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyltransferase"
                     /protein_id="BAQ01310.1"
                     /translation="MYELMLKVKRKIATLLSSFIFRVSFKNFGTKSSIFKPDILQGVK
                     YIEVGDRVVIQPGLWALALKIDNNEPILNIGNNVYIGRFLHIVSVRRVVIEKDVLIAD
                     KVYISDNLHEYKDIHIPVSQQPVVFKGDVVIKEGVWIGENVSIIGACIGRNSVVAANS
                     VVTKDIPDYSVCAGVPAKVIKKYCFERNEWISVS"
     gene            4914..5996
                     /gene="rmlB"
     CDS             4914..5996
                     /gene="rmlB"
                     /note="O088_05"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6 dehydratase"
                     /protein_id="BAQ01311.1"
                     /translation="MKILVTGGAGFIGSALTRYIINSTNDSVVNVDKLTYAGNLHSLK
                     DIDNCDRYVFVHADICDAKALDAILSTHKPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARKYWQTLEGEKKQGFRFHHISTDEVYGDLPHPDDWDNKNSPPLFTENTA
                     YAPSSPYSASKASSDHLVRAWHRTYNLPTIVTNCSNNYGPYHFPEKLIPLVILNALQD
                     KSLPIYGKGDQIRDWLYVEDHARALYTVITKGIVGETYNIGGYNEKKNIEVVETICDI
                     LDEIKPKNTSYREQIIYVADRPGHDRRYAIDASKITLDLGWKPQETFESGIKKTIHWY
                     LDNQEWVQNVMSGAYQDWINKNYGQL"
     gene            6023..6904
                     /gene="rmlA"
     CDS             6023..6904
                     /gene="rmlA"
                     /note="O088_06"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="BAQ01312.1"
                     /translation="MNMSKRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLS
                     TLMLAGIRDILIISTPQDTPRFEQLLGNGEKWGLNIEYKVQESPDGLAQAFIIGEEFI
                     GNDSCALVLGDNVFYGHDLPKELEIAMNQEKGATVFAYHVKDPERYGVVDFDENGKAL
                     SLEEKPLKPKSNYAVTGLYFYDNEVIEMAKQLKPSARGELEITDINRLYLEKNSLSVA
                     IMGRGYAWLDTGTHESLIEAGNFIQTIESRQGLKVSCPEEIAFRKGFIDKKQLAKLAK
                     ELNKNDYGKYLQHLAKD"
     gene            6931..7491
                     /gene="rmlC"
     CDS             6931..7491
                     /gene="rmlC"
                     /note="O088_07"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="BAQ01313.1"
                     /translation="MKIIETPLKDAVIIEPKIFGDERGYFFEVYQKKRYQELGFALEF
                     VQDNRSKSTKNVLRGLHFQKTKPQGKLVSVTQGAVFDVAVDLRPESLTFGQHHSVILS
                     EENFLQFYIPPGFAHGFCVLSDTASFQYKCTDYYDPTDESGLIWNDPDLGIEWPVSHP
                     VVSAKDCFLPSLASIKEQILKGWKNV"
     CDS             7484..8308
                     /note="O088_08"
                     /gene="tll"
                     /codon_start=1
                     /transl_table=11
                     /product="putative nucleotide sugar epimerase"
                     /protein_id="BAQ01314.1"
                     /translation="MSKYTIIGGNGFIGSHIVTLLKEQGHNVVVPDRNSCNSLNGELG
                     KIIYCAGNGDCAESYFSVLEANTVLLAKLLKNAQFEKLVYISSTRVYMNHHSANETDD
                     LLVTAGDNRKLFNLTKLVAEELCIKSERDVTVVRPSNVYGLALNSKLFLPSIIRHAIN
                     NGEINMFVAPEYAKDYVSVNDVAKACVWLAEKQNTNKEIYNVASGFNVTAKQITDVIE
                     KETACKVNWHDGNFPREEFPVTNINKLTNEIPDYKPQHVLDDLKMMIASYKEELAR"
     gene            8311..9768
                     /gene="wzx"
     CDS             8311..9768
                     /gene="wzx"
                     /note="O088_09"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAQ01315.1"
                     /translation="MSGFKRLLKNSLSNIINGFSNVILGIVISPVLLHNLSKVDFSIW
                     SLTIQVGVLIGIFGIGLQVTVGRFVALHLNNQQKLQKTMHQSLFFVLLLSLVCMGGIF
                     FLAKFFFSFFPEVSETSTNAKHILILIGGSFVINNMFSPFVGYFTGIERNDITAGINI
                     LFKVILGTSILLLVHHGLEVIAWIYFAINTFNQLAFYILYKLKNRTQKIKLSLDKNLF
                     RTIVVFFSGLLVWNIAQFLISGIGTFIVGKYSFQELAGFAVLMTLVNAGVGILGAMIN
                     PIIQPMIRMHNLENNHHVELLVNKLIFIFSMIVFIGVFIAWFASVYILGVWLGYQQAT
                     NLHIMFSLLLTAYLIRMIAAPYGLMLVAYGKQLSIAWLPVLEGVLNFALSIFFVRIYG
                     AIGIAYSTFISGVLIMAVYACKYQAEAEYKSKLIFISFLIIPMMIAICLISLVMTQSE
                     IIHCVIYGIQVAFIIVFIIFLIKQVKSIKNLLNQY"
     CDS             9787..10683
                     /note="O088_10"
                     /gene="werQ"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01316.1"
                     /translation="MKKVGLVTVLFNSPGVLPEFYSSVEKQNYQNKHLYIVDNSTNQD
                     SFNLTQEILLGTDIKYTYINNEGNNVGVAHANNQGIEQALKDGCEYILLTNNDLFFQQ
                     EDTISKMISVAEGRQCKIVSPVILSYPEKKVWYAGAFFNKKKATAPHIFEGVNYNDIC
                     AHIPKECDYAPTCFLLVHASVFTTIGMMDSRYFAYYDDTDFLYRANIAGTRVTIINEP
                     LVFHKVSTSTGGGLSVFGAYYLTRNRIFFARKNIETPYCIISIFFTIATRLVYPLFHK
                     TPYKVYKAFVKGIIDGLMLKNK"
     gene            10697..11971
                     /gene="wzy"
     CDS             10697..11971
                     /gene="wzy"
                     /note="O088_11"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAQ01317.1"
                     /translation="MNEISSSTLVNNYNLSTTFIVKSLVGLLLINSLFSGVDFYQIGL
                     MKGLSSIADFGLKIILVFVLLVLFKIRSFNLVKIFFFAFMLLIGAALGAFYHGAEYDK
                     TFALLLNMILWFVIFSYAKELEHNFDIYRFSVKISSLFLGITLILYIMAKFGFHVKVL
                     GGAWLYDENFRFAGTFSEPSLNGYYYGLMFLMVMLSNQKYRLILAFVFAITTYISGAK
                     FSFLIIPVLLGLVYFFKVKGFYNYTYQLIPLSFIVLFVSLAFIYYDLFALIAAHLSNS
                     ETMTYVTRLGFPIVSIWHLSDYPLGSGVYGFKSTLSPFIQNYCQALSGLDVNCNEMRS
                     YISSDDPSAYESFAPKDVLSFIILSFGLPGLLVFVLSISLLSARLKENKNYFIILMYI
                     VASMLFTLPFRFILFYSFFMFQCYIYRMPSNK"
     CDS             11968..13023
                     /note="O088_12"
                     /gene="wbaX"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01318.1"
                     /translation="MIYINARFLTQRKTGVQQYALVLCRELVKHIPDICFLTPKTDLI
                     DENWRDEFNILQIGNRNGHFWEQIELPRYLRSVGNPLLLCFTGLSPAFYKNCYFTIHD
                     MSLYAHPKWFRLLYRAVYKVNYAIQARFARGIFTVSDFSKSEIEKYLAVDSDKITVLR
                     NSVDTSINIKNNIENKAVRRKEILLVGTLEPRKNIEFIINSFLNSQIKGYKLIVVGGL
                     GAAFSKVTFSQHENIIFCGYLSDDDLELKYRQASVFVYPSLYEGFGLPPLEAMQRGCP
                     VMASDRASIPEVCGDAAYYFNPEDSSDFSSKLRELIENYDELSPVLICNGYRRLEQFD
                     VRDVASKLMDVISQRNI"
     CDS             13024..14133
                     /note="O088_13"
                     /gene="wejO"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01319.1"
                     /translation="MKVLQFSKFYPPVHGGIEQVAFDISEGITKSNGQPVDVLCVDPI
                     GERKDDGKFRYKVYRQKLFAQLFSTPLSFSLILRWRAIRNNYDVIHVHLPNPMAVLAL
                     FLFPPKGKIVLHWHSDIVKQKKLLLLFAPLQKWILDKCTCIIVTSPVYGQSSPTLQPY
                     QDKIVCIPIGVDTHVMPLNDELEKSIKKRYQNKKIVFSLGRLVYYKGMEYLIDAAKEL
                     PPDYIVLIGGTGPLIDTLKQKVANDGLSDKVVLLGSINYSDLASYYKSCDVFCLPSIH
                     ESEAFGVVQLEAMSFSRPLVSTNIPRSGVAWVNQHNETGIVVEPNDAKALAKGIVSVV
                     QNSATFSKGAKARFDTMFTKELMVKNIINLYSSLK"
     gene            14142..15569
                     /gene="manC"
     CDS             14142..15569
                     /gene="manC"
                     /note="O088_14"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="BAQ01320.1"
                     /translation="MPLFPVVMAGGSGSRLWPLSRVLYPKQFLCLEGELTMLQATIHR
                     LQGIVCESPVVICNEQHRFIVAEQLRQMNKLTENIILEPIGRNTAPAIALAALAATRA
                     QPEGKALMLVLAADHVIKNEEAFRDSVRKALPYAENGKLVTFGIVPNKAETGYGYIRR
                     GVPCDGVEHADAFDVAQFVEKPNLETAEAYVSCGEYYWNSGMFLFRADRYLEELKKYR
                     PDILEACEKAMSAVEPDLNFIRVDEDAFRACPDESVDYAVMEQTSDAVVVPMDAGWSD
                     VGSWSSLWDISHKTPEGNVVTGDVLSCNTKNSFLYSESGLLTTVGVKDLVVVQTKDAV
                     LIANRNAVQDVKKIVESIKANGRHEHHTHREVYRPWGKYDSIDTGSRYQVKRLTVKPG
                     ESISLQMHHHRAEHWIVVAGAAQVTINEQTKLLGENESIYIPVGSTHCLENPGKIPLE
                     LIEIRSGSYLGEDDIVRFADKYGRV"
     gene            15588..16958
                     /gene="manB"
     CDS             15588..16958
                     /gene="manB"
                     /note="O088_15"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="BAQ01321.1"
                     /translation="MEKLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLG
                     GDVRLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPM
                     DYNGMKLVREGARPISGDTGLRDVQRLAEANDFPPVDETKRGRYQQINLRDAYVDHLF
                     GYINVKNLTPLKLVINSGNGAAGPVVDAIEARFKALGAPVELIKVHNTPDGNFPNGIP
                     NPLLPECRDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLE
                     KNPGAKIIHDPRLSWNTVDVVTATGGTPVMSKTGHAFIKERMRKEDAIYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVAELVCLKGKTLGELVRDRMAAFPASGEINSKLAQPVEAINR
                     VEQHFSREALAVDRTDGISMTFADWRFNLRSSNTEPVVRLNVESRGDVPLMEEKTKLI
                     LALLNK"
     gene            17121..18527
                     /gene="gnd"
     CDS             17121..18527
                     /gene="gnd"
                     /note="O088_16"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ01322.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRLAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            18775..19941
                     /gene="ugd"
     CDS             18775..19941
                     /gene="ugd"
                     /note="O088_17"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ01323.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTFSVESVIK
                     DVVAINPYAIMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLAAFKQQADVIISNRMAEELRDVADKVYTRDLFGSD"
     gene            20051..21064
                     /gene="wzz"
     CDS             20051..21064
                     /gene="wzz"
                     /note="O088_18"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ01324.1"
                     /translation="MRTWKFPSVRVMMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKM
                     TIIISVIVAIALAIGYLAVAKEKWTSTAIITQPDVGQIAGYNNAMNVIYGQTAPKVSD
                     LQETLIGRFSSAFSALAETLDNQEEPEKLTIEPSVKNQQLPLTVSYVGQTAEGAQMKL
                     AQYIQQVDDKVNQELEKDLKDNIALGRKKLQDSLRTQEVVAQEQKDLRIRQIQEALQY
                     ANQAQVTKPQVQQTEDVTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQTRQNLLDI
                     ESLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALRNY
                     NAK"
     gene            complement(21161..>21331)
                     /gene="hisI"
     CDS             complement(21161..>21331)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ01325.1"
                     /translation="QKVGEEGVETALAATVHDRFELTNEASDLMYHLLVLLQDQDLDL
                     TTVIENLRKRHQ"
BASE COUNT     6098 a   4139 c   4750 g   6344 t
ORIGIN
        1 cgctaattac gccatcttac gccagggatt tcataaccag attatcggtg ccaacatcac
       61 caactgtaag ttcagcgact tacaaggcga cgccattgaa tggaacgtgg caattaacga
      121 cagtgatatt ttgatatctg accatgtcat cgagcgcatc aactgtacta acggcaaaat
      181 caactggggc atcggcatag gtcttgcggg aagcacttat gataataatt acccggaaga
      241 ccagtcagtg aaaaactttg tcgtggcaaa tatcacggga tcggattgtc ggcagttgat
      301 ccatgttgaa aatggtaaac attttgttat tcgtaatatc aaagcccgca atatcacgcc
      361 ggatttcagt aagaaagcag gcattgataa cgcgacagtt gctatttacg gttgtgacaa
      421 tttcgtgatt gataatattg aaatgattaa tagcgccggg atgttaatcg gctatggggt
      481 aattaaaggc aaatatctct cgataccgca aaatttccga gtgaataata ttcaactgga
      541 taacacccat cttgcttata aattgcgcgg catccaaatc tccgccggga atgccgtctc
      601 ctttgtggca ctgactaaca ttgagatgaa gcgtgcctcg ctggagcttc acaataaacc
      661 gcaacatctt tttatgcgaa atatcaaagt gatgcaggaa tcctcagttg gaccagcatt
      721 gatcatgaac ttcgacatgc gcaaagacgt tcgcggcgtc tttatggcga aaaaagaaac
      781 cctgctgtct cttgcaaatg ttcatgcggt gaatgaaaaa gggcaaagct ccgtcgatat
      841 cgacagagtt aatcaccata ttattaatat ggaaaagatt aactttagat tgccggaacg
      901 gagggagtag atttgcgacc attcctggaa aaatggagcc atacttagga acaatgctac
      961 tgcaatccac aacgaagcgg cgtaacatca caagtaattc agtaatcaat tcagggtaat
     1021 tgatgctggc gaaaaaaatc gaacaagcta taattcagca accattttac aggtggatga
     1081 aataatgacg aatttaaaag cagttattcc tgtagcgggt cttgggatgc atatgttgcc
     1141 tgccactaag gcgattccca aagagatgct accgatcgtc gacaagccaa tgattcagta
     1201 cattgttgac gagattgtgg ctgcagggat caaagaaatc ctcctggtaa ctcacgcgtc
     1261 caagaacgcg gtcgaaaacc acttcgacac ctcttatgaa ttagaatctc tccttgagca
     1321 gcgcgtgaag cgtcaactgc ttgcggaagt gcagtccatc tgtccaccgg gcgtgaccat
     1381 tatgaacgtg cgtcagggcg aacctttagg tttgggccac tccattttat gtgcacgacc
     1441 tgctattggt gacaatccat ttgtcgtggt gctgccagac gttgtgatag atgacgccag
     1501 cgccgacccg ctgcgctaca accttgctgc catgattgcg cgcttcaacg aaacgggccg
     1561 cagccaggtg ctggcaaaac gtatggcggg cgatctctct gaatactccg tcattcagac
     1621 caaagagccg ctggaccgtg aaggcaaagt cagccgcatt gttgaattta tcgaaaaacc
     1681 ggatcagccg cagacgctgg actcagacat catggccgtt ggtcgctata tgctttcagc
     1741 agatatttgg ccggaacttg aacgcactca gcctggtgca tggggacgta ttcagctgac
     1801 tgatgccatc gctgaactgg cgaaaaaaca gtccgttgat gccatgctga tgacaggtga
     1861 cagctacgac tgcggtaaaa aaatgggtta tatgcaggcg tttgtgaagt atggactacg
     1921 caacctcaaa gaaggggcga agttccgtaa agggattgag aagctgttaa gcgaataatg
     1981 aaaatctgac cggatgtaac ggttgataag aaaattataa cggcagtgaa gattcgtggc
     2041 gaaagtaatt tgttgcgaat attcctgccg ttgttttata taaacaatca ggataacaac
     2101 gagttagcaa taggatttta gtcaaagttt tccaggattt tccttgtttc cagagcggat
     2161 tggtaagaca attagcgttt gaatttttcg ggtttagcgc gagtgggtaa cgctcgtcac
     2221 atcgtaggca tgcatgcagt gctctggtag ctgtaaagcc aggggcggta gcgtgtctag
     2281 gggaaggtca tcgcgtgcgt taagcacaaa aagaaaaaat gaacgtttgc atgtaataag
     2341 cataagtttg tgaatagatc agggaaagat catcagaagt tcactttttg tactaaataa
     2401 ttcgcatttt atgtttaaaa attgagatat tccttattac ctaaagctgt tttttattgc
     2461 ttatacatga tcaaatactc cttacataat taaggagaac aaaatggaac ttaaaaagtt
     2521 gatggaacat atttctatta tccccgatta cagacaagcc tggaaagtgg aacataaatt
     2581 atcggatatt ctactgttga ctatttgcgc cgttatttct ggtgcagaag gttgggaaga
     2641 tatagaggat tttggggaaa cacatctcga ttttttgaag caatatggtg attttgaaaa
     2701 tggtattcct gttcacgata ccattgccag agttgtatcc tgtatcagtc ctgcaaaatt
     2761 tcacgagtgc tttattaact ggatgcgtga ctgccattct tcagatgata aagacttcat
     2821 tgcaattgat ggaaaaacgc tccgacactc ttattacaag agtcgccgca ggggagcgat
     2881 tcatgtcatt agtgcgttct caacaatgca cagtctggtc atcggacaga tcaagacgga
     2941 tgagaaatct aatgagatta cagctatccc agaacttctt aacatgctgg atattaaagg
     3001 aaaaatcatc acaactgatg cgatgggttg ccagaaagat attgcagaga agatacaaaa
     3061 acagggaggt gattatttat tcgcggtaaa aggaaaccag gggcggctaa ataaagcctt
     3121 tgaggaaaaa tttccgctga aagaattaaa taatccagag catgacagtt acgcaattag
     3181 tgaaaagcgt cacggcagag aagaaatccg tcttcatatt gtttgcgatg tccctgatga
     3241 acttattgat ttcacgtttg aatggaaagg gctgaagaaa ttatgcgtgg cagtctcctt
     3301 tcggtccata atagcagaac aaaagaaaga gccagaaatg acggtcagat actatatcag
     3361 ttccgctgat ttaaccgcag agaagttcgc cacagcaatc cgaaaccact ggcacgtgga
     3421 gaataagctg cactggcgtc tggacgtggt aatgaatgaa gacgactgca aaataagaag
     3481 aggaaatgca gcagaattat tttcagggat acggcacatt gctattaata ttttgacgaa
     3541 tgataaggta ttcaaggcag ggttaagacg taagatgcga aaagcagcca tggacagaaa
     3601 ctatctggcg tcagtccttg cggggagcgg gctttcgtaa tcttgcctta agtagcgtag
     3661 atttttccaa atcacattga tattacaaag agtcggtgac gatatgaagc aagctttgtc
     3721 gagaatgaaa ataaaattgt tatcatattt ttataaaaga aaaaatcggt ctacacaatt
     3781 cggtcgctac actgttttat tctgtcgtgc aaatataact aattctatag taggtgatta
     3841 tacgtatttc gcaggcaccg cctccgttaa taattgtgaa attggtaaat tttgttctat
     3901 tgcagaaggc gttaaaatag gccttggaaa acacccagtt gattttcttt caacacatcc
     3961 ggtattttac tcggaaaata cctgcttccc ttatagattg aaaaattata gagttaatga
     4021 aaaagtgatt gaatcaatca ccgaatcaga gagagtcatc ataggcaatg atgtttggat
     4081 tggcgtaaat gccatcgtaa tggatggtgt gacaattggt gatggagcag ttattggagc
     4141 tggggcggtt gttaccaaag atgttcaacc ttatactatc gtaggtggtg ttcctgcgag
     4201 agtcattagg accagacaaa atataaattg ttcttggtgg gaatttgatg tagataccct
     4261 tgtagatttt tcctcaaatt ttaaaaagag gttgtaatgt acgagttaat gttgaaggtc
     4321 aaacgtaaaa tagctactct tctttcttca tttatatttc gcgtttcatt taaaaatttc
     4381 ggaacaaaaa gtagtatttt taaacctgat atattacaag gggtgaaata tatagaagtt
     4441 ggcgatagag tagtaattca accgggatta tgggctttag cattgaaaat tgataacaat
     4501 gaaccgatcc tgaatatagg aaataacgtt tatattggtc gcttcttaca tattgtaagt
     4561 gtgcgccgtg tagttatcga aaaggatgtt ctcatcgccg ataaggtata tatatcagac
     4621 aaccttcatg agtataaaga tattcatatt ccagtaagcc agcagcctgt tgtattcaaa
     4681 ggtgatgtgg ttattaagga aggcgtctgg ataggggaaa atgtttccat cattggtgct
     4741 tgcattggca gaaatagtgt ggtagcggca aactctgtag tgacgaagga tatacctgat
     4801 tattctgttt gtgcaggtgt acctgcaaaa gttatcaaaa aatactgttt cgaacgaaat
     4861 gaatggataa gtgtttctta atgtatacca tttttactta tttgagataa aaaatgaaaa
     4921 tattagttac tggtggtgcc gggttcatcg gttcggcatt aacgcgatac attattaact
     4981 caacaaatga ctctgttgtg aatgttgata agttaaccta cgcaggtaat cttcattctt
     5041 taaaagacat tgataattgc gatcgttatg tttttgttca tgctgatatt tgcgatgcga
     5101 aagcattaga cgcaatctta tcaacacata aacctgatgc agtaatgcat ttggcagcag
     5161 aaagtcatgt tgaccgttca atcaccggcc ctgctgcgtt tattgaaacg aatattgttg
     5221 gaacatacgt tttgcttgaa gcagccagaa aatactggca aaccctagag ggggaaaaga
     5281 aacagggatt ccgtttccat cacatttcta ctgatgaagt atatggtgat ctccctcatc
     5341 cggatgactg ggataataaa aatagtccac cactgtttac tgagaatacc gcatatgctc
     5401 ctagcagtcc atactctgcc tctaaagcat caagcgatca tttggttcgc gcgtggcatc
     5461 gtacttataa tctcccaact attgtgacta actgttcaaa caattatggt ccttaccatt
     5521 tcccagaaaa gttaattccg ctggtgatcc ttaatgcgtt gcaagacaaa tctttgccaa
     5581 tttatggcaa aggcgatcaa atccgtgatt ggttatacgt tgaggatcat gctcgcgcac
     5641 tctataccgt tatcacgaaa ggtatcgtag gtgaaactta caatatcggc ggttataatg
     5701 agaaaaagaa tattgaagtg gtagagacta tttgcgatat ccttgacgaa ataaagccga
     5761 aaaatacctc gtatcgcgaa caaatcattt atgttgccga tcgcccaggt cacgatcgcc
     5821 gctatgccat tgatgccagt aaaatcactc tggacctcgg ttggaaacct caagagacct
     5881 ttgaatctgg tattaagaaa actattcatt ggtatcttga taaccaggag tgggtccaga
     5941 atgttatgag cggtgcctat caggactgga ttaacaaaaa ttacgggcaa ctttaatctt
     6001 ttcaactctg tcataagaag cattgaacat gtcaaaaaga aaaggaatta ttttagccgg
     6061 tggttcgggt actcgccttt accccgtgac gatggcggtt agtaaacagc tgctgccaat
     6121 ctatgataaa ccgatgattt attatccatt aagcacgttg atgcttgcgg gtattcggga
     6181 tattctcatc attagcacac ctcaggatac ccctcgcttt gagcaattac ttggtaacgg
     6241 tgaaaaatgg gggctgaaca tcgaatataa agtccaggaa agtcctgatg gtcttgccca
     6301 ggcatttata attggtgaag aatttatcgg taacgattct tgtgctttag tcctcggcga
     6361 caatgttttc tatggtcacg atttgccaaa agaacttgaa atagcaatga atcaggaaaa
     6421 aggtgctacg gtctttgcct accatgttaa agaccctgaa cgctatggtg tggtagattt
     6481 cgatgagaat ggcaaagcgc tttctttaga agagaaaccg ctgaaaccaa aaagtaatta
     6541 tgctgtgact gggctctatt tttatgataa cgaggtcatt gagatggcta aacaactgaa
     6601 accgtcagct cgcggtgaat tagaaatcac tgatattaat cgcctctacc tggaaaaaaa
     6661 ctcgctctca gttgctatta tgggccgtgg ctatgcctgg cttgatacag gtacgcatga
     6721 gagtcttatt gaggcaggta actttattca gacgatcgaa tcacgtcaag gactcaaagt
     6781 ttcttgcccg gaagagattg ctttccgtaa aggtttcatt gataagaaac agcttgcaaa
     6841 attagccaaa gaactcaata aaaatgatta cggtaaatat ttgcagcatt tagccaaaga
     6901 ttaaaaatta acattaatta gttaacacat atgaaaatta tagaaactcc tttgaaagat
     6961 gctgttatta tcgagcctaa aatttttggt gacgaacgag gctatttttt tgaagtctat
     7021 cagaaaaaac gttatcagga attgggattc gctctggaat ttgtacagga taatcgttcc
     7081 aaatcgacta aaaatgtcct gcgagggctt cattttcaga aaacaaagcc tcagggaaaa
     7141 ctagtttcag taacccaggg ggctgttttt gatgttgccg ttgatctccg tccagagtca
     7201 ctgacatttg gtcagcatca ttcagttatt ctatccgaag aaaattttct tcagttttat
     7261 attcctccag gtttcgctca tggtttctgc gtattaagtg acactgctag tttccagtac
     7321 aaatgcactg attattatga tccaaccgat gaaagcggtc ttatctggaa cgatcccgat
     7381 ctgggcatag aatggcctgt ttctcatcct gtagtttctg ctaaagattg ttttttacct
     7441 tcactagcaa gtatcaaaga acagattctt aaaggctgga aaaatgtcta agtatacaat
     7501 tattggcggt aacggtttta ttggttccca tatcgttaca ttgctaaaag aacaagggca
     7561 taatgtcgtt gttcccgatc gtaatagctg caattcccta aatggtgagt taggtaaaat
     7621 tatttattgt gctggtaatg gtgattgtgc ggaaagctat ttctctgtgc tggaagcaaa
     7681 tacagttttg ttggcaaagt tactgaagaa tgcacagttt gaaaagctgg tatatatttc
     7741 ctcaactcga gtttatatga accaccatag cgcaaatgaa actgatgatc tgctagtaac
     7801 agcgggtgat aacaggaagc tttttaacct gaccaaactg gtggctgagg agctgtgtat
     7861 taagagcgaa cgtgatgtta ctgtggttcg accaagcaat gtctatggtt tagctcttaa
     7921 tagtaaatta tttcttccgt ctattatccg tcatgccatt aacaatggtg aaatcaacat
     7981 gtttgttgca cctgaatatg ctaaggacta tgtttcagtc aatgatgttg ctaaagcatg
     8041 tgtgtggcta gctgaaaaac aaaacaccaa caaagaaata tataatgtcg catctggatt
     8101 taacgtaaca gctaaacaaa tcactgatgt catcgaaaaa gaaacggctt gtaaggtaaa
     8161 ctggcatgat ggtaatttcc ctcgtgaaga gtttcctgtt actaacataa ataaattaac
     8221 taatgagatt ccggattata aaccacaaca tgtgcttgat gatttgaaaa tgatgatagc
     8281 tagttataaa gaagaactgg cgagataaat atgagtggtt ttaagcggtt acttaaaaac
     8341 tctttgtcta atataataaa tggattttca aatgtaattc ttggaatagt gatctctcca
     8401 gttttactgc ataatctttc aaaggtagat ttttctattt ggtcccttac aattcaggtt
     8461 ggggttttga tcggtatttt tggcattggt cttcaggtta cagtagggcg ttttgtcgcc
     8521 cttcatttaa ataatcaaca gaaacttcaa aagacaatgc atcagtcatt gttttttgtg
     8581 ttactgctca gtttggtatg tatgggggga atattctttt tagcaaaatt ctttttctca
     8641 tttttccctg aagtatcaga aaccagtact aatgctaagc acattcttat attaattggt
     8701 ggttcatttg ttattaataa tatgttctct cccttcgttg gctattttac tggtattgag
     8761 cgtaatgata taacagctgg cataaatata ttgtttaaag taattctggg tacgtcgatt
     8821 ctgttgcttg tccaccatgg tcttgaagtt attgcatgga tttattttgc aataaacact
     8881 tttaatcaac ttgcttttta tattttatat aaattaaaaa acagaactca aaaaataaag
     8941 ttatcactag ataaaaattt atttcgaact atagttgtct tttttagcgg actcttggta
     9001 tggaatattg cccagttctt aatttctggt ataggcacct ttatcgtcgg taaatattca
     9061 tttcaggagc tcgctggttt tgccgtatta atgacacttg ttaatgctgg tgtgggaatt
     9121 ttgggagcaa tgatcaatcc tataattcaa cctatgataa ggatgcacaa tctggagaat
     9181 aaccatcatg ttgaacttct ggtcaacaaa ctgatcttca ttttctcaat gattgtcttt
     9241 attggtgttt ttattgcctg gtttgcctct gtatatattc ttggcgtctg gttgggatat
     9301 cagcaagcaa caaacctgca cattatgttt tctttgctgc ttactgctta tcttattaga
     9361 atgattgcag cgccctatgg gcttatgtta gtcgcttatg gcaaacaatt gtcaatcgct
     9421 tggcttccgg tgctcgaagg ggtattgaac tttgcgttat cgattttctt tgtgcgtata
     9481 tatggtgcca ttggaattgc ctactcgacg tttatttcag gcgtattaat catggctgtt
     9541 tacgcttgca agtatcaggc tgaagctgag tataagtcga aactgatatt tatctcgttt
     9601 ctgataatac ctatgatgat agccatttgc ctgatcagtt tggtgatgac tcagtcggaa
     9661 atcatccatt gtgttattta tggcatccag gtggctttta taatagtatt tattatcttc
     9721 ttaataaaac aagtaaaaag catcaagaat ctgttaaatc aatactaata ttgctatggt
     9781 gaaagtgtga aaaaagttgg actcgttact gttttgttca attctccagg tgtgcttcct
     9841 gaattttatt cgagtgttga aaaacaaaat tatcagaaca agcatcttta tattgtagat
     9901 aacagcacta atcaggattc ttttaactta acgcaagaaa ttctcttagg aacagacata
     9961 aagtatacct atattaataa tgaaggaaat aatgttgggg ttgcacatgc caataaccaa
    10021 ggcattgaac aagctttaaa agatgggtgc gagtatatat tgctcactaa taatgatctg
    10081 ttttttcaac aggaagatac tatcagcaaa atgattagtg ttgctgaggg acgacaatgt
    10141 aaaattgttt cacctgtcat attaagttat ccagaaaaaa aagtttggta tgcaggtgca
    10201 ttttttaata agaaaaaagc tacggcacct catatttttg aaggagtcaa ctacaatgat
    10261 atttgcgctc atattccaaa agagtgcgat tacgcaccaa catgtttttt acttgtccat
    10321 gcttcggtgt ttaccactat aggtatgatg gattctcgtt actttgctta ttacgacgat
    10381 actgattttc tctatcgtgc aaacatagcc ggcactcggg taacaattat taatgaacct
    10441 ctagtgtttc ataaagttag tacttctacc ggaggagggt taagtgtatt cggcgcatat
    10501 tatttaacga ggaaccgtat atttttcgcc agaaaaaata ttgaaacacc ttattgtatt
    10561 attagtattt tctttaccat tgcgacccgt ttggtttatc ctcttttcca caaaacaccg
    10621 tataaagtat acaaggcttt tgttaaagga attatcgacg gcctaatgtt aaaaaataaa
    10681 taactaaggg gttaaggtga acgagatttc cagtagcaca cttgtcaata actataattt
    10741 atcgacaact tttattgtca agtcacttgt tggattgtta ttaattaatt ctctttttag
    10801 tggtgttgac ttttatcaga ttggtttgat gaaaggcctt tccagtattg ctgattttgg
    10861 cctgaagatt atccttgtgt tcgtattgct cgtgcttttc aagattcgca gttttaactt
    10921 ggtaaagata ttcttttttg cttttatgct tctcatcggt gctgcgcttg gagcattcta
    10981 tcatggtgct gaatatgata aaacttttgc gcttttacta aatatgatat tatggtttgt
    11041 tatattcagt tatgctaaag aacttgaaca taactttgat atatatcgtt ttagtgtaaa
    11101 aatatcaagt ttatttcttg gtatcacgtt gatactttac atcatggcaa agtttggttt
    11161 tcatgttaaa gtattaggtg gagcttggtt atatgatgag aattttcgct ttgcaggtac
    11221 tttctctgag ccaagtttaa atggctatta ttatggttta atgttcttga tggtcatgct
    11281 gtctaatcaa aagtacagac taattttggc gtttgtgttt gctattacta cctatatttc
    11341 aggtgcgaaa ttttcattcc taataatacc agtgctcctt gggctggttt atttcttcaa
    11401 ggtgaaaggc ttttataatt atacatacca gctcattccg ttatctttta ttgttctttt
    11461 tgttagtctt gcgttcatct actatgacct ttttgcactg attgcagctc atttgtcaaa
    11521 ttctgaaaca atgacttatg ttactcgtct tgggttccca attgtcagca tctggcatct
    11581 tagtgattat ccattaggaa gtggagtata tggctttaag agcacgctat caccttttat
    11641 acagaactac tgtcaggctc tttctggtct ggacgtaaat tgtaacgaga tgaggtccta
    11701 tatatcctcg gatgatccca gtgcatatga aagtttcgcg cctaaagatg ttttaagttt
    11761 cattatatta agttttgggc ttccgggctt gcttgtgttt gtcctgagta tatccttatt
    11821 atcagctaga cttaaggaaa ataagaatta ctttatcatt ctaatgtata ttgtcgcatc
    11881 aatgctcttt acattacctt ttagatttat tcttttttat tctttcttca tgtttcagtg
    11941 ttatatttac agaatgccga gtaataaatg atctatatta atgcaagatt cttgactcag
    12001 cgtaaaaccg gtgtgcagca atatgcatta gttttatgcc gggaactcgt taaacacatt
    12061 cctgatatct gttttttgac accgaaaact gatctcattg atgagaattg gcgggacgag
    12121 tttaatatcc ttcaaatagg aaatcgtaat ggacattttt gggaacaaat cgaactccct
    12181 cgttatctaa gaagcgttgg taatccgttg ctgctctgtt ttactggctt atcacctgct
    12241 ttttataaaa attgttactt tactatccat gatatgtcat tgtacgcaca tcccaagtgg
    12301 ttccgtttgt tatatcgtgc agtatacaag gttaactatg ctattcaggc aagattcgct
    12361 agaggtatct tcacggttag tgatttttcg aaatcagaga tagagaaata tctggcggta
    12421 gactctgaca agatcactgt attacgaaat tcagtagaca catctattaa tatcaagaat
    12481 aatattgaaa ataaagcggt taggcgtaaa gagattttat tggttggtac cttagaacct
    12541 agaaaaaata tagagtttat tattaattct tttttaaatt cgcaaatcaa aggttataag
    12601 ctcatcgttg ttggagggtt aggagctgct ttctcaaagg tgactttttc tcagcatgag
    12661 aacattatat tctgtggcta tctatcagac gatgacttag agttaaagta tagacaagct
    12721 tcagtttttg tctatccttc actgtatgaa ggtttcggcc ttcctccact tgaagcgatg
    12781 caacgtggct gtcccgtaat ggcttctgac cgcgcaagca tccctgaagt ttgtggtgat
    12841 gctgcttact atttcaatcc agaggactca tcagatttta gtagtaagtt acgtgagctg
    12901 atcgaaaatt atgatgagct cagccctgta ttgatttgca atggatatcg tagactggaa
    12961 caatttgacg tacgggatgt tgcatcgaaa cttatggatg tcatctctca aaggaatatt
    13021 tgaatgaagg ttttacaatt tagtaaattt tatcctccag tacacggggg aattgagcag
    13081 gttgcatttg atattagcga aggaattaca aaaagtaatg gtcagcctgt tgacgttctc
    13141 tgtgttgatc ctattgggga aagaaaagac gacggaaagt ttcgttataa ggtttaccgc
    13201 cagaaattgt ttgcacagct tttctcgaca ccgctatctt tctccttgat tttacgctgg
    13261 agagcgatca gaaataacta tgatgttatt cacgttcatc ttccaaatcc aatggctgtg
    13321 ttggcgcttt ttttatttcc accaaaagga aaaatagttc tccactggca cagcgatatt
    13381 gttaagcaaa aaaaactatt attgcttttt gcgccgttgc aaaaatggat tttagataaa
    13441 tgtacctgta ttatagttac aagtcctgtt tatgggcagt cttctccaac tttgcaacct
    13501 tatcaggata aaattgtttg tattcctatt ggagttgata ctcatgttat gccgctaaat
    13561 gatgagcttg aaaaaagtat aaaaaaacgc tatcaaaata aaaagatagt tttttctctt
    13621 gggcgtcttg tttattacaa aggtatggaa tatctgattg atgctgcgaa ggagcttcct
    13681 ccggattaca ttgttcttat tggtggaaca ggcccactaa ttgacacatt aaagcaaaag
    13741 gttgctaatg atggattgtc agataaagtc gttcttcttg gtagcatcaa ttattcggat
    13801 ttagcatcct attacaaatc atgcgacgtt ttttgtttgc catctattca tgaatctgaa
    13861 gcatttggtg tagtccagtt agaggctatg agtttctcca gaccgcttgt gtcgacaaat
    13921 attccccgaa gtggcgtggc ttgggttaat cagcataacg agactggtat tgttgttgag
    13981 cctaatgatg ccaaagcact tgctaaaggt atagtttctg ttgttcaaaa cagtgcaacg
    14041 tttagtaaag gcgctaaggc cagatttgat accatgttta ctaaagaatt gatggttaaa
    14101 aatataatta atttatattc atctttaaag tgagtgcaat tatgccatta tttcctgttg
    14161 ttatggccgg aggctctggt agtcgtttat ggccgctttc tcgtgttctc tatccaaaac
    14221 aatttctttg tctggaaggt gaactgacta tgttacaagc gacaatacac cgactgcagg
    14281 gcatcgtgtg tgaaagtcct gtcgttattt gtaatgaaca gcaccgcttt attgttgctg
    14341 agcaacttcg ccagatgaat aaactcaccg agaatattat cctcgaaccg attggtcgta
    14401 atactgctcc ggcgatagcg ttggctgcac tagccgcaac tcgtgcccag cccgaaggta
    14461 aggcgctcat gctggttctt gccgccgacc acgtcataaa aaatgaagaa gcattccgtg
    14521 attccgttcg taaggcgctt ccttatgctg aaaatggaaa gcttgtgaca tttggtatag
    14581 tcccgaataa agcagagact ggctatggtt acattcgccg cggtgtgccg tgcgatggtg
    14641 ttgaacatgc agatgcattc gacgtcgcgc aattcgttga gaaacctaat cttgaaacgg
    14701 ctgaagccta cgtttcctgc ggtgaatact actggaatag tgggatgttc ctgttccgcg
    14761 ccgatcgcta tcttgaggaa ctaaaaaaat accgcccgga tattcttgaa gcatgcgaaa
    14821 aggcaatgag tgctgttgag cctgacctta attttattcg cgttgatgaa gatgctttca
    14881 gggcttgtcc tgatgagtca gttgactatg ctgtgatgga gcagacttcc gatgctgttg
    14941 ttgtgccaat ggatgcgggc tggagtgatg tcggttcctg gtcttcgcta tgggatatta
    15001 gccataagac gccagagggt aatgtcgtca caggtgatgt attatcctgc aataccaaaa
    15061 acagcttcct gtattctgaa tcagggcttt tgactacagt tggcgtgaaa gatttggttg
    15121 ttgtgcagac taaggatgct gtattgattg ccaatcgtaa cgccgttcag gatgtgaaga
    15181 aaatagtcga atcgataaaa gctaacgggc gccacgaaca tcatactcat cgcgaagttt
    15241 atcgtccctg gggtaaatat gactcgattg ataccgggag ccgttatcag gttaagcgat
    15301 tgacggtaaa accaggtgaa agtatctcac ttcagatgca tcaccatcgt gctgagcatt
    15361 ggattgtcgt cgcaggagct gcacaagtaa caattaacga acaaactaaa ctcctcggtg
    15421 aaaacgagtc tatctatatt cctgttgggt caacacactg tctggagaat cctggaaaga
    15481 tccctttaga actgattgag attcgctcag gttcttatct gggagaggat gacattgtac
    15541 gttttgctga caaatatggt cgtgtctgag attacggtaa aattagtatg gaaaaattaa
    15601 cctgttttaa agcctacgat attcgcggaa aattaggcga agaactgaat gaagatattg
    15661 cctggcgcat tggtcgcgcc tatggcgaat ttctcaaacc gaaaaccatt gtgttaggcg
    15721 gtgacgtccg cctcaccagc gaaaccttaa aactggcgct ggcgaaaggt ttacaggatg
    15781 cgggcgtcga tgtgctggat atcggtatgt ccggcaccga agagatctat ttcgccacgt
    15841 tccatctcgg cgtggatggc ggcattgaag ttaccgccag ccataacccg atggattata
    15901 acggcatgaa actggtgcgc gaaggggctc gcccgatcag cggtgatacc ggactgcgcg
    15961 atgtccagcg cctggctgaa gccaacgact ttcctcccgt cgatgaaacc aaacgcggtc
    16021 gctatcagca aatcaacctg cgtgacgctt acgttgatca cctgttcggt tatatcaatg
    16081 tcaaaaacct cacgccgctc aagctggtga tcaactccgg gaacggcgca gcgggtccgg
    16141 tagttgacgc catcgaagcc cgctttaaag ccctcggcgc accggtggaa ttgatcaaag
    16201 tgcacaacac gccggacggt aatttcccca acggtattcc taacccgcta ctgccagaat
    16261 gccgcgacga cacccgcaat gcggtcatca aacacggcgc ggatatgggc attgcctttg
    16321 atggcgattt tgaccgctgc ttcctgtttg acgaaaaagg gcagtttatc gaaggctact
    16381 acattgtcgg cctgctggca gaagcgttcc tcgaaaaaaa tcccggcgcg aagatcatcc
    16441 acgatccgcg tctctcctgg aacaccgttg atgtggtgac ggccacaggt ggcaccccgg
    16501 taatgtcgaa aaccggacac gcctttatta aagaacggat gcgcaaggaa gacgccatct
    16561 acggtggcga aatgagcgcc caccattact ttcgtgattt tgcttactgc gacagcggca
    16621 tgatcccatg gctgctggtc gccgaactgg tgtgtctgaa aggaaaaacg ctgggagagc
    16681 tggtgcgcga ccggatggcg gcgtttccgg caagcggtga gatcaacagc aaactggcgc
    16741 aacccgttga ggcgattaac cgcgtggaac agcattttag ccgtgaggcg ctggcggtgg
    16801 atcgcaccga tggcatcagc atgacctttg ccgactggcg ctttaacctg cgctcctcca
    16861 acaccgaacc ggtggtgcgg ttgaatgttg aatcgcgcgg tgatgtgccg ctgatggaag
    16921 aaaagacaaa acttatcctt gcgttattga acaagtaatt cagtaatttc atataaataa
    16981 gttttaaaag acggaaaaga tgagatattc agtgtggtat agcaaaggta atgctattca
    17041 ccatctctat gagtgagtta acatctatac cacatttaag ccgcacactc ggcggtgacc
    17101 acccctgaca ggagtaaaca atgtcaaagc aacagatcgg cgtcgtcggt atggcagtga
    17161 tggggcgcaa ccttgcgctc aacatcgaaa gccgtggcta taccgtctct attttcaacc
    17221 gttcccgtga aaagacggaa gaagtgattg ccgaaaatcc aggcaagaaa ctggttcctt
    17281 actatacggt gaaagagttt gttgaatctc tggaaacgcc tcgtcgcatc ctgttaatgg
    17341 tgaaagcagg tgctggcacg gatgctgcta ttgattccct caagccatac ctcgataaag
    17401 gtgacatcat cattgatggt ggtaatacct tcttccagga caccattcgc cgtaaccgtg
    17461 agctttctgc cgaaggcttt aacttcatcg gtaccggtgt ttccggtggt gaagagggcg
    17521 cgctgaaagg tccttccatc atgcctggtg ggcagaaaga agcctatgaa ctggttgcac
    17581 caatcctgac caaaatcgct gcagtagctg aagacgggga gccatgcgtt acctatattg
    17641 gtgccgatgg tgcaggtcac tatgtgaaga tggttcacaa cggtattgaa tacggcgata
    17701 tgcagctgat tgctgaagcc tattctctgc ttaaaggtgg cctgaatctc tctaacgaag
    17761 aactggcaca gacctttacc gagtggaata acggtgaact gagcagctac ctgatcgaca
    17821 tcaccaaaga tatcttcacc aaaaaagatg aagacggtaa ctacctggtt gatgtgattc
    17881 tggatgaagc agcaaacaaa ggtaccggta aatggaccag ccagagcgcg ctggatctcg
    17941 gcgaaccact gtcgctgatt accgagtctg tgtttgctcg ttatatttct tctctgaaag
    18001 atcagcgcct tgccgcgtct aaagttctct ctggcccgca agctcagcca gcaggcgaca
    18061 aggctgagtt tatcgagaaa gttcgtcgtg cgctgtatct gggcaaaatc gtttcttacg
    18121 ctcagggctt ctctcagctg cgtgctgcgt ctgaagagta caactgggat ctgaactacg
    18181 gcgaaatcgc gaagattttc cgtgctggct gcatcatccg tgcgcagttc ctgcagaaaa
    18241 tcaccgatgc atatgccgaa aatccgcaga tcgctaacct gctgctggcc ccgtacttca
    18301 agcaaattgc cgatgactat cagcaggcgc tgcgtgatgt tgttgcttat gcagtacaga
    18361 acggtatccc ggttcccacc ttcgccgctg cggttgccta ttatgacagc taccgtgccg
    18421 ctgttctgcc tgcgaacctg atccaggcac agcgtgacta tttcggtgca catacttata
    18481 agcgcattga taaagaaggt gtgttccata ctgaatggct ggattaatct tatttaacta
    18541 acaataaatt gaggcctggc gtatattgcg ccgggctttt ttttgccaat tatcttatag
    18601 actaaatttc actgcttaat attaacttaa taaatatcag ctattcttat aaagaaaatc
    18661 tgaattgttt ttcgttgcgt tgaccatctg acaacgtagc gttaaaactt ttagctctta
    18721 tcaggatgct aaaaacatca tgattcacag ttaagttaat tctgagagca tgaaatgaaa
    18781 atcaccattt ccggtactgg ctatgtaggt ttgtcaaacg ggcttctaat cgcacaaaat
    18841 catgaggttg tggcattaga tattttaccg tcacgcgttg ctatgctgaa tgatcggata
    18901 tctcctattg ttgataagga aattcagcag tttttgcaat cagataaaat acactttaat
    18961 gccacattag ataaaaatga agcctaccgg gatgctgatt atgtcatcat cgccactcca
    19021 accgactatg atcctaaaac taattatttc aatacattca gtgtagaatc agtaattaaa
    19081 gacgtagtag cgataaatcc ttatgcaatt atggtcataa aatcaacggt tcccgttggt
    19141 tttaccgcag cgatgcataa gaaatatcgt actgaaaata ttattttctc ccccgaattc
    19201 ctccgtgaag gtaaagccct ttacgataat ctccatccgt cacgtattgt catcggtgag
    19261 cgttcagaac gcgcagaacg ttttgcggcg ttgttacagg aaggcgcgat taagcaaaat
    19321 atcccgaccc tgttcaccga ttcgaccgaa gcagaagcga ttaaactttt tgcaaacacc
    19381 tacctggcga tgcgcgtggc atactttaac gaactggata gctacgcaga aagtttaggt
    19441 ctgaatactc gccagattat cgaaggcgtt tgtctcgatc cgcgtattgg caaccattac
    19501 aacaacccgt catttggtta tggtggttat tgtttgccga aagataccaa gcagttactg
    19561 gcgaactatc agtctgttcc gaataacctg atctcggcaa ttgtcgatgc taaccgcacg
    19621 cgtaaagatt ttattgccga tgccattttg tcacgcaagc cgcaagtggt cggtatttat
    19681 cgtctgatta tgaagagtgg ttcagataac ttccgtgcgt cttctattca ggggattatg
    19741 aaacgtatca aggcgaaagg tgttgaagtg atcatctacg agccagtgat gaaagaagac
    19801 tcattcttca actctcgcct ggaacgtgat ctcgccgcct tcaaacaaca agccgacgtc
    19861 attatttcca accgtatggc agaagagctt agggatgtgg cagataaggt ctacacccgc
    19921 gatctctttg gcagcgacta acatcttgtt atcagggcta tttacgccct gattgtcttt
    19981 tgttacctcc gcaataattc attattttta tcacttatcc tatagcattc acggggatta
    20041 tcgctaaact atgcggactt ggaaatttcc gtcagttagg gtaatgatga gagtagaaaa
    20101 taataatgtt tctgggcaaa accatgaccc ggaacagatt gatttgattg atttactagt
    20161 gcagttgtgg cgtggcaaga tgacaatcat catttccgtc attgtggcta ttgccctggc
    20221 tattggatat ttggcagtag cgaaggagaa atggacgtca acagcaatta tcactcagcc
    20281 cgacgtgggg caaattgctg gctataacaa tgccatgaat gttatctatg gtcagactgc
    20341 accgaaagta tcggatttgc aggagacgtt aattggtcgc ttcagttctg ccttctctgc
    20401 attagcagaa acgctggata atcaggaaga gccagagaaa cttaccatcg aaccttctgt
    20461 taagaaccag caattaccat tgactgtttc ttatgttggg caaacagcag agggcgcaca
    20521 aatgaagttg gcccaataca ttcagcaagt tgatgataaa gtgaatcaag agctagaaaa
    20581 ggatctcaaa gacaacattg ctctgggacg gaaaaaattg caggattctt taagaaccca
    20641 ggaagtggtt gcgcaggagc agaaagatct gcgtatccgt cagattcagg aagcgttgca
    20701 gtatgcgaat caggcgcagg tgacaaagcc acaggttcag cagactgaag atgtgacgca
    20761 agatacgttg ttccttttgg ggagcgaagc gctggagtcg atgattaagc atgaggcgac
    20821 ccgtccgttg gtgttctcgc caaactacta tcagactcgt caaaacctgc tggatattga
    20881 aagcttaaaa gttgatgatc ttgatattca tgcttaccgt tatgtgatga aaccgacgtt
    20941 acctattcgt cgcgatagtc cgaaaaaggc aatcaccttg attctggcgg tgctgctggg
    21001 cggcatggtt ggcgcgggga ttgtgctggg gcgtaacgct ctgcgtaatt acaacgcgaa
    21061 gtaatctttt cggttttaaa gaaaaagggc agggtggtga caccttgccc gttttttttg
    21121 ccggatgcga caacaatatc gcatccgctt accccgcaac tcactgatgc cgtttacgca
    21181 ggttctcaat caccgttgtt aaatccagat cctgatcctg caacaatacc agcaggtgat
    21241 acatcaagtc agatgcctcg ttggtcagct caaagcggtc atgtaccgtt gctgccagtg
    21301 cggtttccac gccttcttcg cccactttct g
//
