LOCUS       AB812039               20886 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli genes for O-antigen biosynthetic locus, partial
            sequence, strain: H77.
ACCESSION   AB812039
VERSION     AB812039.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 20886)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..20886
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="H77"
                     /db_xref="taxon:562"
                     /note="serogroup:O90"
     gene            <1..893
                     /gene="wcaM"
     CDS             <1..893
                     /gene="wcaM"
                     /codon_start=3
                     /transl_table=11
                     /product="colanic acid biosynthesis protein"
                     /protein_id="BAQ01349.1"
                     /translation="RQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDRDILISDHVI
                     ERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGKHF
                     VIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGKYL
                     SIPQNFRVNNIQMDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQHLF
                     MRNIKVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNEKGQSSVDIDR
                     VNHHIVNVEKINFRLPERRE"
     gene            1051..2046
                     /gene="gne"
     CDS             1051..2046
                     /gene="gnu"
                     /note="O090_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4-epimerase"
                     /protein_id="BAQ01350.1"
                     /translation="MNDNVLLIGASGFVGTRLLETAIADFNIKNLDKQQSHFYPEITQ
                     IGDVRDQQALDQALAGFDTVVLLAAEHRDDVSPTSLYYDVNVQGTRNVLAAMEKNGVK
                     NIIFTSSVAVYGLNKHNPDENHPHDPFNHYGKSKWQAEEVLREWYNKAPTERSLTIIR
                     PTVIFGERNRGNVYNLLKQIAGGKFMMVGAGTNYKSMAYVGNIVEFIKYKLKNVAAGY
                     EVYNYVDKPDLNMNQLVAEVEQSLNKKIPSMHLPYPLGMLGGYCFDILSKITGKKYAV
                     SSVRVKKFCATTQFDATKVHSSGFVAPYTLSQGLDRTLQYEFVHAKKDDITFVSE"
     gene            2289..3182
                     /gene="galF"
     CDS             2289..3182
                     /gene="galF"
                     /note="O090_02"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ01351.1"
                     /translation="MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNV
                     RQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRS
                     QVLAKRMPGELSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLS
                     ADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFRKGIEKLLSE"
     CDS             3492..4511
                     /note="O090_03"
                     /codon_start=1
                     /transl_table=11
                     /gene="gne"
                     /product="putative UDP-glucose 4-epimerase"
                     /protein_id="BAQ01352.1"
                     /translation="MVIFVTGGAGYIGSHTILELLNNGHDVVSIDNFVNSSIESLKRV
                     EQITNKKIISYQGDIRDKNLLDEIFSRHHIDAVIHFASLKSVGESKLKPLEYYSNNVG
                     GTLVLLECMKRYNINKMIFSSSATVYGNNSIPPHTEDRRIGETTNPYGTSKFIIEIIL
                     SDYCDSDNNKSVIALRYFNPIGAHKSGMIGENPNGIPNNLVPYISKVAQNQLPVLNIY
                     GNDYPTKDGTGVRDYIHVCDLAKGHVKALEYMFLNDVNYEAFNLGTGQGYSVLEIVKM
                     FEIVTKKSIPVAICNRREGDVAESWASADLAHKKLSWKAEKKLKEMIEDVWRWQTNNP
                     NGYKK"
     CDS             4530..5546
                     /note="O090_04"
                     /codon_start=1
                     /transl_table=11
                     /gene="wcmB"
                     /product="glycosyltransferase"
                     /protein_id="BAQ01353.1"
                     /translation="MKNVGFIVTKSEIGGAQTWVNEISNLIKEECNIFLITSEEGWLT
                     HKDVFAGVFVIPGIKKYFDFLTLFKLRKILKENNISTLIASSANAGVYARLVRLLVDF
                     KCIYVSHGWSCLYNGGRLKSIFCIVEKYLSLLTDVIWCVSKSDEKKAIENIGIKEPKI
                     ITVSNSVPQMPRCNNKQLQYKVLFVGRLTHPKRPELLANVISKKPQYSLHIVGGGERL
                     ESLKKQFSECENIHFLGEVNNFYNYHEYDLFSLISDSEGLPMSGLEAHTAAIPLLLSD
                     VGGCFELIEGNGLLVENTEDDIGYKLDKIFDDYENYREQAIRASGKFVIENYASAYKS
                     IILG"
     gene            5573..6694
                     /gene="gmd"
     CDS             5573..6694
                     /gene="gmd"
                     /note="O090_05"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="BAQ01354.1"
                     /translation="MAKVALITGITGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERV
                     DHIYQDPHTCNPKFHLHYGDLTDTSNLTRILCEVQPDEVYNLGAMSHVAVSFESPEYT
                     ADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVA
                     KLYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYL
                     GNMDSLRDWGHAKDYVKMQWMMLQQEQPEDFVIATGVQYSVRQFVEMAAERVGIKLRF
                     EGTGVDEKGIVVSVNGEDAPAVKPGDVIVKVDPRYFRPAEVETLLGDPTKAHEKLGWK
                     PEITLREMVSEMVANDLEAAKKHSLLKSHGYDVAIALES"
     gene            6697..7662
                     /gene="fcl"
     CDS             6697..7662
                     /gene="fcl"
                     /note="O090_06"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthetase"
                     /protein_id="BAQ01355.1"
                     /translation="MSRQRIFIAGHRGMVGSAIRRQLEQRGDVELVLRTRDELNLLDS
                     RAVHDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKL
                     LFLGSSCIYPKLAKQPMAESELLKGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRS
                     VMPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMA
                     AASIHVMELAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASK
                     PDGTPRKLLDVTRLHQLGWYHEISLEAGLASTYQWFLENQDRFRG"
     gene            7662..8165
                     /gene="gmm"
     CDS             7662..8165
                     /gene="gmm"
                     /note="O090_07"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose mannosyl hydrolase"
                     /protein_id="BAQ01356.1"
                     /translation="MMFLRQEDFATVVRSTPLVSLDFIVENSRGEFLLGKRTNRPAQG
                     YWFVPGGRVQKDETLEAAFERLTMAELGLRLQITAGQFYGVWQHFYDDNFSGTDFTTH
                     YVVLGFRFRVAEEELLLPDEQHDDYRWLTPDALLASNNVHANSRAYFNHDPSAVIGLD
                     KKDVKNV"
     gene            8149..9606
                     /gene="manC"
     CDS             8149..9606
                     /gene="manC"
                     /note="O090_08"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="BAQ01357.1"
                     /translation="MSKMSDVPLIAVVMAGGTGSRLWPLSREHYPKQFLQLSGENTLL
                     QSTLLRLSPLSCETPLVITNEQHRFVVAEQLRQINQLSDNIILEPCGRNTAPAIALSA
                     FTALKRNEQQDPILLVLAADHVINKTDVFCNAIKNSISIVEQGNILTFGIIPDYAETG
                     YGYIEKGSIVKESQRGVGNTFYHVEQFVEKPNRSRAEEYISSGKYLWNSGMFMFKASV
                     YLEELKKYRPDIYDICEKTVSSSYHDLDFIRLSKDVFQNCPSESIDFAVMEKTKRCIV
                     YPVDIGWNDVGSWQSLWDVSDKTPTGDVCKGDILTYNTKNNYIHSESALVAAVGVEDI
                     VIVQTKDAILVSKKSEVQDVKKIVQMLKMQERSEYLSHREEFRPWGKFDAIEQGDRYK
                     VKKIVVKPGEGLSLRMHHHRSEHWIVLSGTAKVTLNNKTFLVTANESVYIPLGATYSL
                     ENPGIIPLNLIEVSSGDYLGEDDIVRQKERYKIDD"
     gene            9610..10983
                     /gene="manB"
     CDS             9610..10983
                     /gene="manB"
                     /note="O090_09"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="BAQ01358.1"
                     /translation="MKKLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLG
                     GDVRLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPM
                     DYNGMKLVREGARPISGDTGLRDVQRLAEANDFPPVDETKRGRYQQINLREAYVDHLF
                     GYINVKNLTPLKLVINSGNGAAGPVVDAIEARFKALGAPVELIKVHNTPDGNFPNGIP
                     NPLLPECRDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLE
                     KNPGAKIIHDPRLSWNTVDVVTAAGGTPIMSKTGHAFIKERMRKEDAIYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVAELVCLKGKTLGELVRDRMAAFPASGEINSKLTHPVEAINR
                     VEQHFSREALAVDRTDGISMAFANWRFNLRSSNTEPVVRLNVESRGDQLVMENNTAII
                     INLLKEK"
     gene            10996..12267
                     /gene="wzx"
     CDS             10996..12267
                     /gene="wzx"
                     /note="O090_10"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAQ01359.1"
                     /translation="MSIISSFKNNIFLRNTMFNYIGMIWMGGGIIVLIPFYIKLLGPH
                     GWGIVSACLSIQAMLLILDAGCSQIMPRDIAKTNTPENIFFAYFWIYIAVAFVGAVFL
                     TSSAGWLAFRWFNAGHSSRELEFCIRLLAIQFLFQFANNLNIGFWNGTQKQFNTNLSQ
                     VCFFSCKHCVALISLMVNPEPIVYIVSFAVVTCIEFIFNFLWITRNNIDLKGLIDNNI
                     LIQLIDLVKENYIFSFGVIVGVFVSQLDKILLSHYVETQLYGVYVIVAQLGLSFLQLQ
                     YPLMKSLLPALSSQGEKSIFNVLSLKKMIIMLLVLAFPIGLTIIFSSDILYLWTRNHY
                     IANHGGGALALICLSVLINIPYTFIYTNLVRLNAGGIILFSNIISALSMFILFHFMKG
                     NNSISIGGMMWIAYASISFSIGGIFLLMRAR"
     CDS             12264..12917
                     /note="O090_11"
                     /codon_start=1
                     /transl_table=11
                     /gene="werU"
                     /product="putative acetyltransferase"
                     /protein_id="BAQ01360.1"
                     /translation="MNIIKEYILLPICYLIKNIILCFQGVSVYPGARIRHVTFEENIK
                     VYNNTLLYNSNIGRHTYIQRNCTILNTSIGRYCSIAESVKMGLGKHPVSEYISTHPFC
                     YGKNSIHWLSKSCPPPDSHTFEETKRIMIGHDVCLGANTVILDGVTVGNGAIIGAGSV
                     VTKNIPPYAVAAGVPCKVLYYRFNDDTRNKLEKMKWWEKDYEELELILSEFKYPDSE"
     gene            12925..14082
                     /gene="wzy"
     CDS             12925..14082
                     /gene="wzy"
                     /note="O090_12"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAQ01361.1"
                     /translation="MMQITIPKSNDFRRFFNPVILILMSIVLNTFFQLYTSEEEWNSF
                     FIFNQKPDYTVFFISLVFYLFFLFGAFFAYLFNYQKHSNHRSHYLYNFSFYNGLLKFV
                     FYSNVISLIVTQYYMHEANIYISGGVSAQTIESQIASSPLGIHGISVMLGYFGIIMYG
                     ISRLIKDNRAIVFISILVIIIKFISYAKLQSLLYVLLALMLFSRRRISINKGVIIGGV
                     VIFLFSFTRIIRNPEQNLSLSFDFLFRFVGGFYFGSPVVNFNYVIQNNIQDVFYFFNW
                     FLPQKIIPASPISLEFPDVTSPIGFVGSAYVSLGIFSVIYAYLVGFIIQLIYLQRNTS
                     PFAFVFQPFVIMACIFAMMYNNFVNMIFFILPLIFSYLVVIKTICARKEDV"
     CDS             14083..14820
                     /note="O090_13"
                     /codon_start=1
                     /transl_table=11
                     /gene="wcmC"
                     /product="glycosyltransferase"
                     /protein_id="BAQ01362.1"
                     /translation="MISVIMCINKYDSYVMPAINSILNQTYKKYELIIVANGNEASDI
                     ARVLKNNIKQTENVNIIETNIGQLAFSLNLAISKAKYDIIARMDSDDIALPNRLQKQI
                     KYLIDNELDLIGTSINLIDENDGFLGVRLYPRQKLINRYIMFRNCFAHPSIMFRKDLF
                     LKTRGYNGGFNSEDYDLWLRMRSLKPRWDNMEEPLLNYRVHSNSTQKSKLAYYECAGY
                     SLREFLKKKSIMSFLSCTYHFIKALVK"
     CDS             14828..15727
                     /note="O090_14"
                     /codon_start=1
                     /transl_table=11
                     /gene="wcmD"
                     /product="glycosyltransferase"
                     /protein_id="BAQ01363.1"
                     /translation="MMYCCLSGGLGNQMFQYAAAYILKQHFPDTILVLDDSYYFNQPQ
                     KDTIRHLELDQFKIIFDRFSSKDEKVKINRLRKHKKIPLLNSFLQFTAIKLCNKYSLN
                     DASYYNPESIKNIDVACLFSFYQDSKLLNEHRDLILPLFEIRDDLRVLCHNLQIYSLI
                     TDSKNITSIHVRRGDYVNNKHAAKFHGTLSMDYYISAMEYIESECGSQTFIIFTDDVI
                     WAKEKFSKYSNCLVADADENKFSVIDMYLMSLCNNNIIANSTYSWWGAWLNRSEDKLV
                     IAPKQWYISGNECSLKNENWIAM"
     gene            15848..17254
                     /gene="gnd"
     CDS             15848..17254
                     /gene="gnd"
                     /note="O090_15"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ01364.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSIKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKEQRVAASKVLSGPQAQPAGDKGEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            17503..18669
                     /gene="ugd"
     CDS             17503..18669
                     /gene="ugd"
                     /note="O090_16"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ01365.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDNIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            18759..19793
                     /gene="wzz"
     CDS             18759..19793
                     /gene="wzz"
                     /note="O090_17"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ01366.1"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLV
                     QLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYNNAINVIYGS
                     AAPKVSEIQSMLIGRFSTTFSALAETLDNQEEPEKLTIEPTVKNQSLPLAVSYVGKTP
                     EGAQKQLAKYIQQVDDQVNEELEQDLKDNIALQMKNLQDSLKTQEVVAQEQKDLRIRQ
                     IQEALQYANQAQVTKPQIQQTQDVTQDTMFLLGSEALESMIKHEATRPLVFSSNYYQT
                     RQNLLDIDNLDVDKLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLG
                     RNALRNYNAK"
     gene            complement(19979..20590)
                     /gene="hisI"
     CDS             complement(19979..20590)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ01367.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVNIAPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ"
BASE COUNT     6030 a   4088 c   4697 g   6071 t
ORIGIN
        1 tacgccaggg atttcataac cagattatcg gtgccaacat caccaactgt aaatttagtg
       61 atttacaggg cgacgccatt gaatggaacg tggcgattaa cgaccgtgat attttgatat
      121 ctgaccatgt catcgagcgc atcaactgta ccaacggcaa aatcaactgg ggtatcggca
      181 taggccttgc gggaagtacc tacgataata actacccgga agaccaggca gtgaaaaact
      241 ttgtcgtggc gaatatcacg ggatcggatt gtcggcagtt gatccatgtt gaaaatggta
      301 aacattttgt tattcgtaat atcaaagccc gcaatatcac gccggatttc agcaagaaag
      361 caggcattga taacgcgaca gttgctattt acggttgtga caatttcgtg attgataata
      421 ttgaaatgat taatagcgct gggatgttaa tcggctatgg ggtaattaaa ggcaaatatc
      481 tctcaatacc gcaaaatttc cgagtgaata atattcaaat ggataacacc catcttgctt
      541 ataaattgcg cggtatccaa atctctgccg ggaatgctgt ctcctttgtg gcgctgacta
      601 acattgagat gaagcgtgcg tcgctggagt tacacaacaa accgcaacat ctttttatgc
      661 gaaatatcaa ggtgatgcag gaatcctcag ttggacccgc attgagcatg aacttcgaca
      721 tgcgcaaaga cgttcgcggc gtctttatgg cgaaaaaaga aacactgctg tcacttgcaa
      781 atgttcatgc ggtgaatgaa aaagggcaaa gctccgtcga tatcgacaga gttaatcacc
      841 acattgttaa tgtggaaaag attaacttta gattgccaga acggagggag tagatttgcg
      901 accattcata aacttactgg atataatgtt ctaaaagatt ataatcctca cactaactgt
      961 taaagctggg gctgggcagc attgactact cagggaaggt actcatcttt atcttgtgtt
     1021 tcttacgtaa caaccagact aaagtgattt atgaacgata acgttttgct cataggagct
     1081 tccggattcg taggaacccg actacttgaa acggcaattg ctgactttaa tatcaagaac
     1141 ctggacaaac agcagagcca cttttatcca gaaatcacac agattggcga tgttcgtgat
     1201 caacaggcac tcgaccaggc gttagccggt tttgacactg ttgtactact ggcagcggaa
     1261 caccgcgatg acgtcagccc tacttctctc tattatgatg tcaacgttca gggtacccgc
     1321 aatgtgctgg cggccatgga aaaaaatggc gttaaaaata tcatctttac cagttccgtt
     1381 gctgtttatg gtttgaacaa acacaaccct gacgaaaacc atccacacga tcctttcaac
     1441 cactacggca aaagtaagtg gcaggcagag gaagtgctgc gtgaatggta taacaaagca
     1501 ccaacagaac gttcattaac catcatccgt cctaccgtta tcttcggtga acggaaccgc
     1561 ggtaacgtct ataacttgct gaaacagatc gctggcggca agtttatgat ggtgggcgca
     1621 gggactaact ataagtccat ggcttatgtt ggaaacattg ttgagtttat caagtacaaa
     1681 ctgaagaatg ttgccgcagg ttacgaggtt tataactacg ttgataagcc agacctgaat
     1741 atgaaccagt tggttgctga agttgaacaa agcctgaaca aaaagatccc ttctatgcac
     1801 ttgccttacc cactaggaat gctgggtgga tattgctttg atatcctgag caaaattact
     1861 ggcaaaaaat acgctgtcag ctctgtgcgc gtgaaaaaat tctgcgcaac aacacagttt
     1921 gacgcaacga aagtgcattc ttcaggtttt gtggcaccgt atacgctgtc gcaaggtctg
     1981 gatcgaactc tgcagtatga attcgttcat gccaaaaaag acgacataac gtttgtttct
     2041 gagtaatgca gacgagtcag agaaaaaagg accaggttgg actacgatta ttcggaaaga
     2101 ggtactgatt aaattatcag tatgtggatt tccgagtaat ccgagtaacc cagatgctga
     2161 tggtgtgtag tgttatcgta aggtttaatc aaagttatgc ggaactaagc tatggtatat
     2221 agccataccg tttggctaac ctatggcaat aatttacgca ctatcagcca cttagaggta
     2281 ggaaaataat gacgaattta aaagcagtta taccggtagc gggtcttggg atgcatatgt
     2341 tgcctgccac taaggcgata cccaaagaga tgctaccgat cgtcgacaag ccaatgattc
     2401 agtacattgt tgacgagatt gtggctgcag ggatcaaaga aatcctcctg gtaactcatg
     2461 cgtccaagaa cgcggtcgaa aaccacttcg acacctctta tgaattagaa tctctccttg
     2521 aacagcgcgt gaagcgtcaa ctactggcgg aagtacaatc tatctgtccg ccgggcgtga
     2581 ccattatgaa cgtgcgtcag ggtgaacctt taggtttagg ccactccatt ttatgtgcgc
     2641 gacctgccat tggtgacaat ccatttgtcg tggtgctgcc agacgttgtg atcgacgacg
     2701 ccagcgccga cccgctacgc tacaaccttg ctgccatgat tgcgcgcttc aatgaaacgg
     2761 gacgcagcca ggtgctggca aaacgtatgc cgggtgagct ctctgaatac tcagtcattc
     2821 agacaaaaga accactggat cgtgaaggta aagtcagccg cattgttgaa ttcatcgaaa
     2881 agccggatca gccgcagacg ctggactcag acatcatggc cgttggtcgc tatgtgcttt
     2941 ctgccgatat ttggccggaa cttgaacgta ctcagcctgg tgcatgggga cgtattcagc
     3001 tgactgatgc cattgccgag ctggcgaaaa aacagtccgt tgatgccatg ctgatgaccg
     3061 gcgacagcta cgactgcggt aaaaaaatgg gttatatgca ggcgtttgtg aagtatggac
     3121 tacgcaacct gaaagaaggg gcgaagttcc gtaaagggat tgagaagctg ttaagcgaat
     3181 aaaaattaat catccatata tggtggattg aataaaaata gaacggcagt gaacattcaa
     3241 aagcagagat gcttacatta taagaatgtt cctgtctttt atttaaagta tttaataaca
     3301 ataagttacc gcaagtatcg ctcggacata gattttcctt gtatctgact tcgtttggtt
     3361 agacaattgg aaaatagtgg aaagtattaa atgcttagta cctatgattc attttcagtg
     3421 agttggtaac tgttaagcca agggcggtag cgtgtgtttt tctctcaatc ctcatggtaa
     3481 aggaggttta tatggtgatt ttcgtaacag gcggtgcagg atatattgga tcccatacca
     3541 tacttgagtt acttaataat ggtcatgatg tcgtttcgat agataatttt gtcaattcct
     3601 ctatagaatc attaaaaaga gtagagcaaa taactaataa gaaaattatt tcttatcaag
     3661 gtgatatccg tgataaaaat ctacttgatg agattttttc aagacaccat atcgatgctg
     3721 taattcactt tgcatcgtta aaatctgtag gtgagtctaa gttaaagccc ttagagtatt
     3781 attctaataa tgttggtgga actttagtat tacttgaatg catgaagaga tataacatta
     3841 ataaaatgat atttagctct tctgctactg tttatgggaa taacagtatc cctccccata
     3901 cggaagatag acgaattggt gaaactacaa acccatatgg gacatcgaaa tttataatag
     3961 aaataatttt gagtgattat tgtgatagtg ataataataa atcagtaatt gcactgcgtt
     4021 actttaatcc aatcggagca cataagtccg ggatgattgg tgaaaatcct aacgggattc
     4081 ctaataatct ggttccttat atatctaaag ttgcacaaaa tcaacttcct gtattaaata
     4141 tttatggcaa cgattatcca actaaagatg gtacaggagt aagagactat atacatgtct
     4201 gtgatttggc taaagggcat gttaaagcat tagaatatat gtttttaaat gatgtcaatt
     4261 atgaagcttt taatttaggc actggtcaag gttattctgt tttagagatt gtaaaaatgt
     4321 ttgagatagt cactaaaaag agtatacctg ttgctatttg taatagacgt gagggggatg
     4381 ttgcggagtc atgggcgtct gctgatttag cacataaaaa gctttcctgg aaagcggaaa
     4441 aaaaattgaa agaaatgatc gaagatgtat ggcgttggca aacaaacaat ccaaatggat
     4501 ataaaaaata atttttggaa ttttgatata tgaaaaatgt tggttttatt gttacaaaat
     4561 cagaaattgg tggtgcacaa acatgggtaa atgaaatatc taaccttatt aaagaggaat
     4621 gtaatatatt tcttattaca tctgaagaag gatggctcac acataaagat gtctttgccg
     4681 gagtttttgt cataccaggt attaaaaaat attttgactt ccttacattg tttaaattga
     4741 gaaaaatttt aaaagaaaat aacatttcaa cgttaatagc aagttctgct aatgccggag
     4801 tttatgccag gttagttcga ttactagtcg actttaaatg tatttatgtt tcgcatggat
     4861 ggtcttgttt atataatggt ggtcgcctaa aatcaatttt ttgcattgtg gaaaaatacc
     4921 tttctttatt aactgatgtt atatggtgtg tttccaaaag tgatgaaaaa aaggcaattg
     4981 agaatattgg tataaaagaa ccaaagataa tcacagtatc gaattcagtg cctcagatgc
     5041 cgagatgtaa taataaacaa ctccagtata aggttctgtt tgttggtagg ttaacacacc
     5101 ctaagcgccc cgagttgtta gcgaatgtaa tatcgaaaaa gccccagtat agcctccata
     5161 tcgtaggagg gggggaaagg ttagaatcat tgaagaaaca attcagtgaa tgtgaaaata
     5221 ttcatttttt gggtgaggtc aataattttt ataactatca tgagtatgat ttattttcac
     5281 tgatatccga tagtgaaggt ttgcctatgt caggccttga ggctcacaca gctgcaatac
     5341 cactcctgtt aagtgatgtg ggcggatgtt ttgaattaat tgagggtaat gggttacttg
     5401 tggaaaatac tgaagacgac attggatata aattggataa aatattcgat gactatgaaa
     5461 attatcggga acaggcaatt cgtgcctccg ggaaatttgt tatcgagaac tatgcttcag
     5521 catataaaag cattatttta ggttgagtat ttttaagaac aggaaatgta aaatggctaa
     5581 agtcgctctc attactggca taaccggaca agacggttct tacctggcag agtttctgct
     5641 ggaaaaaggt tacgaggtgc atggtattaa gcgtcgtgca tcgtcattca acaccgagcg
     5701 cgtggatcac atttatcagg atccgcacac ctgcaacccg aaattccatc tgcattatgg
     5761 cgatctgaca gatacctcca acctgacgcg cattttgtgt gaagtgcagc cggatgaagt
     5821 gtacaacctg ggcgcaatga gtcacgttgc ggtttctttt gagtcaccgg aatataccgc
     5881 tgacgtcgat gcgatgggta cgctgcgcct gctggaggcg atccgcttcc tcggtctgga
     5941 aaagaaaacc cgtttttatc aggcttccac ttctgaactg tacggtctgg tgcaggaaat
     6001 tccgcagaaa gaaaccacgc cgttctaccc acgctctccg tatgcggtcg ccaaactgta
     6061 tgcctactgg atcaccgtta actaccgcga atcctacggc atgtacgcct gtaacggtat
     6121 tctcttcaac catgaatccc cgcgccgcgg cgaaaccttc gttacccgca aaatcacccg
     6181 cgcaatcgca aacatcgccc aggggctgga atcgtgcctg tacctcggca atatggattc
     6241 cctgcgtgac tggggccatg ccaaagacta cgtaaaaatg cagtggatga tgctgcaaca
     6301 ggaacagccg gaagatttcg tcatcgcgac cggcgttcag tactccgtgc gtcagttcgt
     6361 ggaaatggcg gcggagcgag tcggaatcaa actgcgtttt gaaggcacag gtgtagatga
     6421 gaaggggata gtggtttctg ttaatggtga ggatgctcca gcagttaaac ctggagatgt
     6481 aatcgttaag gttgatccgc gctacttccg tccggctgaa gttgaaacgc tgctcggcga
     6541 cccgaccaaa gcgcacgaaa aactgggctg gaaaccggaa atcaccctca gagagatggt
     6601 gtctgaaatg gtggctaatg acctcgaagc ggcgaaaaaa cactctctgc tgaaatctca
     6661 cggctacgac gtggcgatcg cgctggagtc ataagcatga gtagacaacg catttttatc
     6721 gctggccatc gcggaatggt cggttctgcc atcaggcggc agctcgaaca gcgcggtgat
     6781 gtggaactgg tattacgcac ccgcgacgag ctgaacctgc tggacagccg cgcggtgcat
     6841 gatttctttg ccagcgaacg cattgaccag gtctatctgg cggcggcgaa agtgggcggc
     6901 attgttgcca acaacaccta tccggcggat ttcatctacc agaacatgat gattgagagc
     6961 aacatcattc acgccgcgca tcagaacgac gtgaacaaac tgctgtttct tggatcgtcc
     7021 tgtatctacc cgaaactggc aaaacagccg atggcagaaa gcgagctgtt gaagggcacg
     7081 ctggagccga ctaacgagcc ttatgctatt gccaaaatcg ccgggatcaa actgtgcgaa
     7141 tcttacaatc gccagtacgg acgcgattac cgctcagtca tgccgaccaa cctgtacggg
     7201 ccgcatgaca acttccaccc gagtaactcc catgtgatac ctgcattgct gcgtcgcttc
     7261 cacgaggcga cggcacagaa tgcaccggac gtggtggtgt ggggcagcgg tacaccgatg
     7321 cgcgaatttc tgcacgtcga tgatatggcg gcggcaagca ttcatgtgat ggagttggcg
     7381 cacgaagtct ggctggaaaa cacccagccg atgttgtcgc acattaacgt cggcacgggc
     7441 gttgactgca ccatccgtga actggcgcaa accatcgcca aagtggtggg ttacaaaggt
     7501 cgggtggttt ttgatgccag taaaccggat ggtacgccgc gcaaactgct ggatgtgacg
     7561 cgcctgcatc agcttggctg gtatcacgaa atctcactgg aagcggggct tgccagcact
     7621 taccagtggt tccttgagaa tcaagaccgc tttcgggggt aatgatgttt ttacgtcagg
     7681 aagactttgc cacggtagtg cgctccactc cgcttgtctc tctcgacttt attgtcgaga
     7741 acagtcgcgg cgagtttctg cttggcaaaa gaaccaaccg cccggcgcag ggttactggt
     7801 ttgtgccggg agggcgcgtg cagaaagacg aaacgctgga agccgcattt gagcggctga
     7861 cgatggcgga actggggctg cgtctgcaga taacagcagg ccagttttac ggtgtctggc
     7921 agcactttta tgacgacaac ttctccggca cggatttcac cactcactat gtggtgctcg
     7981 gttttcgctt cagggtagcg gaagaagagc tgttactgcc ggatgagcag catgacgatt
     8041 accgctggct gacgccggac gcgctgctcg ccagtaacaa tgttcacgct aacagccgag
     8101 cttattttaa tcatgatcca agtgctgtta ttggtttaga taaaaaggat gtcaaaaatg
     8161 tctgatgtac cgttgattgc tgttgtaatg gctggtggta cgggtagccg tctttggccc
     8221 ctctcaagag agcactatcc gaagcaattt ctgcaattat caggtgagaa tactttatta
     8281 cagtcaactt tattacgact atccccgctt tcttgcgaaa ctccattagt aataactaac
     8341 gagcagcatc gttttgtggt cgcagaacaa ttgcgtcaaa taaaccaatt aagcgataac
     8401 attattcttg aaccatgtgg aagaaatact gcaccagcta tagcactttc agcatttaca
     8461 gccttaaagc gtaatgaaca acaagatcct atacttttag ttcttgcagc tgaccatgtt
     8521 ataaacaaaa cagatgtttt ttgtaatgct attaaaaatt ccatttcaat tgttgaacaa
     8581 ggaaatattt taacatttgg tattattcct gattatgcag aaactggtta cggttatata
     8641 gaaaaaggga gtatagttaa agaatcacaa cgtggagttg gtaatacatt ctatcacgtg
     8701 gaacaatttg ttgaaaaacc taatcgctca agggctgaag agtatatctc ctcaggtaaa
     8761 tatctctgga atagtgggat gtttatgttc aaagcatcag tatatttaga ggagttaaaa
     8821 aaatacagac ctgatatata cgatatatgt gaaaaaacag tttcttcgtc ctaccatgat
     8881 cttgatttta tacgactttc gaaagatgtt tttcaaaatt gtccatcgga atcaattgat
     8941 tttgcagtaa tggaaaaaac aaagcgttgt atagtctatc ccgttgatat tggttggaac
     9001 gatgttggat cttggcaatc attgtgggac gttagtgata aaactcctac aggggacgtt
     9061 tgcaaaggtg atatcctgac ttataataca aaaaataatt atattcattc ggagtcagcc
     9121 ttagtagccg ctgtaggtgt ggaggatatt gttattgttc agacgaaaga tgcaattcta
     9181 gtttcaaaaa aatccgaagt tcaggatgtt aagaaaattg ttcaaatgct taaaatgcaa
     9241 gaacgttctg aatatctatc acatcgcgag gaatttcgtc cttggggaaa gtttgatgct
     9301 atagaacagg gagatcgata taaggtcaaa aagattgtcg ttaaaccagg ggaagggcta
     9361 tccttacgta tgcatcatca tcgttcagag cattggattg tcctttcagg tacagcaaaa
     9421 gtaacgttaa ataataaaac tttcttagtt actgctaatg aatccgttta tattcctctg
     9481 ggtgctactt atagccttga aaatccaggt ataattcctc tcaatcttat tgaagttagt
     9541 tcaggagatt atttaggtga ggatgatatt gttcgtcaaa aagaacgtta caaaatagat
     9601 gactaataaa tgaaaaaatt aacctgcttt aaagcctacg atattcgcgg aaaattaggc
     9661 gaagaactga atgaagatat tgcctggcgt attgggcgtg cctatggcga atttctcaaa
     9721 ccgaaaacta ttgttttagg tggtgatgtc cgcctcacca gcgaaacctt aaaactggcg
     9781 ctggcgaaag gtttacagga tgcgggcgtc gatgtgctgg atatcggcat gtccggcacc
     9841 gaagagatct atttcgctac gttccatctc ggcgtggatg gcggcatcga agttactgcc
     9901 agccataacc cgatggatta caacggcatg aagctggtgc gcgagggggc tcgcccgatc
     9961 agcggtgata ccggactgcg cgatgtccag cgtctggcag aagccaacga cttccctccc
    10021 gtcgatgaaa ccaaacgcgg tcgctatcag caaatcaatc tgcgtgaagc ttacgttgat
    10081 cacctgttcg gttatatcaa cgtcaaaaac ctcacgccgc tcaagctggt gattaactcc
    10141 gggaacggcg cggcgggtcc ggtggtggac gccattgaag cccgctttaa agccctcggc
    10201 gcaccggtgg agttaatcaa agtgcataac acgccggacg gcaatttccc caacggtatt
    10261 cctaacccgc tactgccgga atgtcgcgac gacacccgca atgcggtcat taaacacggc
    10321 gcggatatgg gcattgcttt tgatggcgat tttgaccgct gtttcctgtt tgacgaaaaa
    10381 gggcagttta ttgagggtta ctacattgtc ggtttgctgg cagaggcgtt cctcgaaaaa
    10441 aatcccggcg cgaagatcat ccacgatcca cgtctctcct ggaacaccgt tgatgtggtg
    10501 actgccgcag gcggtacgcc aataatgtcg aaaaccggac acgcctttat taaagaacgt
    10561 atgcgtaagg aagacgctat ctacggtggc gaaatgagcg cccaccatta cttccgtgat
    10621 ttcgcttact gcgacagcgg catgatcccg tggctgctgg tcgccgaact ggtgtgcctg
    10681 aaagggaaaa cgctgggcga actggtgcgc gaccggatgg cggcttttcc ggcaagtggt
    10741 gagatcaaca gcaaactcac gcaccccgtt gaggcgatta accgcgtgga acagcatttt
    10801 agccgtgagg cgctggcggt ggatcgcacc gatggcatca gtatggcctt tgccaactgg
    10861 cgctttaacc tgcgctcctc caacaccgaa cctgttgtgc gtttgaacgt tgaatcaaga
    10921 ggtgatcagc tcgtgatgga aaataatacg gcaattatta ttaatttatt aaaagaaaaa
    10981 taaaaaaaca tctatatgtc aataatatcc tcttttaaaa ataatatatt cttacgaaac
    11041 acaatgttta attacattgg tatgatttgg atgggggggg ggataatagt ccttataccc
    11101 ttttatatca agctactagg tccccatgga tggggtatcg tctctgcttg tttaagtatc
    11161 caggctatgt tacttattct ggatgctggg tgttcgcaga ttatgcctcg cgatattgct
    11221 aaaacgaata cgccagaaaa catatttttt gcatattttt ggatatatat tgctgttgct
    11281 tttgttgggg cggtttttct aaccagttcg gctggttggt tggcatttag atggtttaat
    11341 gcagggcata gcagtaggga gttagagttt tgtataagat tgcttgcaat tcaattccta
    11401 tttcaatttg caaataatct caatataggt ttttggaatg gtactcaaaa gcaatttaat
    11461 actaatttaa gccaagtgtg ttttttttca tgtaaacatt gtgtcgcgct gatttcattg
    11521 atggtaaatc cagaacctat agtatatata gtttccttcg cagtggttac ctgtatagaa
    11581 tttattttta attttttatg gattactcgc aataatatag atcttaaagg cttaatagat
    11641 aataatatat tgattcaatt aattgatttg gttaaagaga actatatatt ttcatttggt
    11701 gtgattgttg gtgtgtttgt ttcacagtta gataaaatat tattatcaca ctacgtggaa
    11761 acacagttat atggagtata tgttattgtt gcacaactgg gattatcttt tttacagcta
    11821 caatatcctt tgatgaagtc attgttacca gctttatcat cacaagggga aaagagtata
    11881 tttaatgttc tatcgttaaa aaaaatgata attatgctat tggtattagc tttccctatt
    11941 ggtctgacaa taatattttc atctgatatt ttatatttat ggacaagaaa tcattatata
    12001 gctaatcatg gagggggggc tttagctctt atttgcctct cagttttaat aaatatacca
    12061 tatacattta tctatacaaa ccttgttcga ttaaacgcag ggggaattat actgttcagt
    12121 aatattattt ctgcattaag catgtttatt ttatttcatt tcatgaaagg aaataactct
    12181 atttcaattg gcggcatgat gtggatagca tatgcaagta tatctttttc aattggcgga
    12241 atatttttat taatgagagc aagatgaata taataaaaga atatatactg ttacctatat
    12301 gctatttaat taaaaacatt attctatgtt ttcaaggcgt tagtgtttat cccggagcga
    12361 gaataaggca tgtaacattt gaggagaata taaaagtgta taacaataca ttgctttata
    12421 attcaaatat tggacgtcat acttatattc agaggaattg tacaatattg aacacgtcaa
    12481 tcggtcggta ttgttctatt gcagaaagtg tgaaaatggg attaggtaaa catcctgtgt
    12541 cggaatatat atcgacgcat ccattctgtt atgggaaaaa ttcaatacat tggctttcta
    12601 aaagctgtcc acctccggat tcgcatacat ttgaagaaac caaaagaatt atgattggtc
    12661 atgatgtatg tttgggtgcg aatacggtta tattggatgg agtaactgta ggtaatggcg
    12721 ctattattgg ggctggctca gttgttacta agaatatacc tccttatgct gttgctgcag
    12781 gggttccttg taaagtactt tattatcgtt ttaatgatga tacaagaaat aagttggaaa
    12841 aaatgaaatg gtgggaaaaa gattatgaag aactagaact gattctttca gaatttaaat
    12901 atccagactc ggaataagat taagatgatg cagataacaa ttccaaaaag taatgatttt
    12961 agacgtttct ttaatcccgt tatattaatt ttaatgtcaa tcgttttaaa cacttttttt
    13021 caattatata ccagtgaaga agaatggaat tcattcttta tatttaatca aaaacctgat
    13081 tatacggtgt tttttatatc tttagttttt tatttgtttt ttctttttgg ggcttttttt
    13141 gcgtatttat ttaattatca aaaacatagc aaccatagaa gccactactt atacaacttt
    13201 tctttttata atgggttatt aaagtttgtt ttttattcaa atgtaataag tttaattgta
    13261 acccagtatt acatgcacga agctaatata tatattagcg gtggtgtctc tgctcaaaca
    13321 atagagtctc agattgcttc atctccgctg ggaatacatg gaatatctgt aatgttgggc
    13381 tattttggta ttattatgta tggtatatct cgtttgataa aagataatcg agctattgtt
    13441 tttataagta tattggttat aataatcaaa tttattagtt atgcgaaatt gcaatcttta
    13501 ttatatgttt tattagcttt gatgctattt tccagacgga gaatatctat taataaagga
    13561 gttataatag gaggtgtagt cattttttta ttttcattta cgcgcataat tcgaaatcct
    13621 gaacaaaatt tatcattgag ttttgatttt ttatttagat ttgttggcgg tttttatttc
    13681 ggttcacctg ttgttaattt taactatgtt attcaaaata atatacagga tgtgttttat
    13741 ttcttcaatt ggtttttacc tcaaaaaatc attccagcgt caccaattag cttggagttt
    13801 ccagatgtta cctcacctat aggttttgta ggaagtgctt atgtttcatt gggtatattc
    13861 agcgtaatat atgcctattt ggttgggttc ataattcaat taatatattt acagcgaaat
    13921 acgtctcctt ttgcatttgt ttttcaacca tttgtcatta tggcctgcat atttgcgatg
    13981 atgtataata attttgtaaa tatgatattt ttcatattgc cgcttatatt ttcatattta
    14041 gtggttataa aaactatatg cgctagaaag gaagatgttt aaatgatttc tgtaattatg
    14101 tgtataaata aatatgattc atatgtaatg cctgcgataa atagcatatt gaatcaaact
    14161 tataaaaaat atgagttaat aattgttgct aatggcaatg aagccagtga cattgcccgt
    14221 gtcttaaaaa ataacataaa acaaacagag aatgttaata ttattgaaac caatataggg
    14281 caattggctt tttctttaaa tttggcaata tccaaagcta aatatgatat catcgcgagg
    14341 atggattctg atgacatagc cttacctaac cgacttcaaa agcaaattaa atatcttata
    14401 gataatgaac ttgatttaat tggaacctca ataaatctaa ttgatgaaaa tgatggtttt
    14461 ttaggtgtaa ggctttaccc cagacaaaaa ttaataaata gatatataat gtttcgaaac
    14521 tgtttcgcac atccttcaat aatgttcaga aaagatttgt ttcttaaaac aagagggtat
    14581 aatggtggtt ttaactctga agattatgat ttgtggttaa gaatgcgaag cttaaaacca
    14641 cgttgggata atatggaaga gcctttgtta aattaccgtg ttcactcaaa ttcaacacag
    14701 aagtctaaac tggcatatta tgaatgtgct gggtattctt tgcgagaatt tcttaaaaag
    14761 aaaagtataa tgagttttct ttcttgtaca tatcatttta ttaaagcatt agttaaataa
    14821 ggacttaatg atgtattgct gtctatccgg tgggttaggt aatcaaatgt tccaatatgc
    14881 tgcagcctat atccttaagc aacattttcc tgatactata ttagtgcttg atgatagtta
    14941 ttatttcaac cagcctcaaa aagatactat acgacatctt gagcttgatc aatttaaaat
    15001 tatttttgat aggtttagtt ctaaagatga aaaagtaaaa ataaatcgtt tgaggaaaca
    15061 taaaaaaata ccactgctta acagttttct tcagttcact gcaattaaac tgtgtaataa
    15121 atattcatta aatgatgctt cttattacaa tccggaatca attaaaaaca ttgatgttgc
    15181 gtgtctattc tcattttacc aagattctaa attattaaat gaacataggg atttaatttt
    15241 gccccttttt gaaatacgtg atgatcttcg cgtgttatgt cataacctac aaatatattc
    15301 cttaattact gactctaaga atataacgtc aattcatgtg cgacgtggag attatgtaaa
    15361 taataaacat gctgcaaaat ttcacggcac tctaagtatg gattattata ttagtgcaat
    15421 ggaatacatt gaaagtgaat gtggctctca gacatttata atctttacag atgatgtcat
    15481 atgggcaaag gaaaaattct caaaatatag caattgcttg gttgctgatg ctgatgaaaa
    15541 caaatttagt gtaattgata tgtatttaat gtcattgtgt aataataata ttattgcaaa
    15601 cagcacatat agttggtggg gggcatggct aaacaggtca gaagataagc tagtcatcgc
    15661 gcctaaacaa tggtacatat ccggaaatga atgctctctt aaaaatgaaa actggatagc
    15721 aatgtagagt tttcattgtt tcaattctca ttgacattac atgtgagatt tacctgtatt
    15781 tatattaaca tctgcatcat atccaagccg cacacttggc ggtaaccacc cctgacagga
    15841 gtaaacaatg tcaaagcaac agatcggcgt agtcggtatg gcagtgatgg ggcgcaacct
    15901 tgcgctcaac atcgaaagcc gtggttatac cgtctctatt ttcaaccgtt cccgtgaaaa
    15961 gacggaagaa gtgattgccg aaaatccagg caagaaactg gttccttact atacggtgaa
    16021 agagtttgtt gaatctctgg aaacgcctcg tcgcatcctg ttaatggtga aagcaggtgc
    16081 tggcacggat gctgctattg attccatcaa gccgtacctc gataaaggtg acatcatcat
    16141 tgatggtggt aatacattct tccaggacac cattcgccgt aaccgtgagc tttctgccga
    16201 aggctttaac ttcatcggta ccggtgtttc cggtggtgaa gagggcgcgc tgaaaggtcc
    16261 ttccattatg cctggtggcc agaaagaagc ctatgaactg gttgctccga tcctgaccaa
    16321 aatcgccgca gtagctgaag acggtgagcc atgcgttacc tatattggtg ccgatggcgc
    16381 aggtcactat gtgaagatgg ttcacaacgg tattgaatac ggtgatatgc agctgattgc
    16441 tgaagcctat tctctgctta aaggtggcct gaatctctct aacgaagaac tggcacagac
    16501 ctttaccgag tggaataacg gtgaactgag cagctacctg atcgacatca ccaaagacat
    16561 cttcactaaa aaagatgaag acggtaacta cctggttgat gtgatcctgg atgaagcggc
    16621 taacaaaggt accggtaaat ggaccagcca gagcgcgctg gatctcggcg aaccgctgtc
    16681 gctgattacc gagtctgtgt ttgcacgtta tatctcttct ctgaaagagc agcgtgttgc
    16741 cgcatctaaa gttctctctg gcccgcaagc gcagccagct ggcgacaaag gtgagttcat
    16801 cgagaaagtt cgtcgtgcgc tgtatctggg caaaatcgtt tcttacgctc agggcttctc
    16861 tcagctgcgt gcggcgtctg aagagtacaa ctgggatctg aactacggcg aaatcgcgaa
    16921 gattttccgt gctggctgca ttatccgtgc gcagttcctg cagaaaatca ccgatgctta
    16981 tgccgaaaat ccgcagatcg ctaacctgct gctggctccg tacttcaagc aaattgccga
    17041 tgactaccag caggcgctgc gtgatgtcgt tgcttatgca gtacagaacg gtatcccggt
    17101 tccgaccttc gctgctgcgg ttgcctatta cgatagctac cgtgccgctg ttctgcctgc
    17161 gaacctgatc caggcacagc gtgactattt cggtgcgcat acttataagc gcattgataa
    17221 agaaggtgtg ttccatactg aatggctgga ttaatctgat ttaaccaaca ataaaattga
    17281 ggcccggcgt atattgcacc gggctttttt ttgccaatta tcttatagac taaatttcac
    17341 tgcttaatat taacttaata aatatcagct attcttataa agaaaatctg aattgttttt
    17401 cgttgcgttg accatcgaac aacgtagcgt taaaactttt agctcttatc aggatgctaa
    17461 aaacatcatg attcacagtt aagttaattc tgagagcatg aaatgaaaat caccatttcc
    17521 ggtaccggtt atgtaggctt gtcaaacggg cttctaatcg cacaaaatca tgaggttgtg
    17581 gcattagata ttttaccgtc acgcgttgct atgctgaatg atcggatatc tcctattgtt
    17641 gataaggaaa ttcagcagtt tttgcaatca gataacatac actttaatgc cacattagat
    17701 aaaaatgaag cctaccgtga tgctgattat gtcatcatcg ccactccaac cgactatgat
    17761 cctaaaacta attatttcaa tacgtctagt gtagaatcag taattaaaga cgtagtagag
    17821 ataaatcctt atgcggttat ggtcatcaaa tccacggttc ccgttggttt taccgcagcg
    17881 atgcataaga aatatcgtac tgaaaatatt attttctccc ccgaattcct ccgcgaaggt
    17941 aaagcccttt acgataacct tcatccgtca cgtattgtca tcggtgagcg ttcggaacgc
    18001 gcagaacgtt ttgcggcgtt attacaggaa ggcgcgatta agcaaaatat cccgaccctg
    18061 ttcaccgatt caaccgaagc agaagcgatt aaacttttcg ctaataccta tctggcgatg
    18121 cgcgtagcat actttaatga actggatagc tatgcagaaa gtttgggtct gaatacgcgt
    18181 cagattatcg aaggtgtttg tctcgatccg cgtattggca accattacaa caatccgtcg
    18241 tttggttatg gtggttattg tctgccgaaa gataccaagc agttactggc gaactaccag
    18301 tctgtgccga ataacctgat ttcggcaatt gtcgatgcta accgcacgcg taaagacttt
    18361 attgccgatg ccattttgtc acgcaaaccg caagtggtgg gtatttatcg tctgattatg
    18421 aagagcgggt cagataactt ccgtgcgtct tccattcagg ggattatgaa acgtatcaag
    18481 gcgaaaggcg ttgaagtgat catatacgag ccggtgatga aagaagattc attcttcaac
    18541 tctcgtctgg aacgtgatct cgccactttc aaacaacaag ccgacgtcat tatctccaac
    18601 cgtatggcag aagagcttaa ggatgtggca gacaaagtct acacccgcga tctctttggc
    18661 agcgactaac atcctgttat cagggcgatt ttcgccctga ttctctcatg ttccctttgt
    18721 aataattcat tgtttttatc atttatccta tagcattcat ggcgattatc gctaaactat
    18781 ggcgacttaa aattatttcg tccgttaggg taatgatgag agtagaaaat aataatgttt
    18841 ctgggcaaaa ccatgatccg gaacagattg atttgattga tttactggtc caactatggc
    18901 gcggcaagat gactatcatc atttctgtca ttgtggctat tgccctggct atagggtatc
    18961 tggccgttgc caaagaaaag tggacttcaa cagctatcgt tactcaacct gatgtgggac
    19021 aaatcgctgg ttataacaat gccataaatg tgatttatgg ttcggcagcg ccgaaagtgt
    19081 ctgagatcca gtcgatgtta attggtcgtt tcagcacgac attttctgca ttagcagaaa
    19141 cgctggataa tcaggaagaa cctgaaaaac tgaccattga gcctaccgtt aaaaatcagt
    19201 cattaccttt agcggtttct tatgtcggta aaacacctga aggtgcgcag aagcagctgg
    19261 cgaagtatat ccagcaagtt gacgaccagg taaatgaaga actggaacaa gacctgaaag
    19321 acaacatcgc gctgcaaatg aaaaacttgc aggattctct gaagacgcag gaagtggtcg
    19381 ctcaagaaca gaaagatctg cgtatccgtc agattcagga agcgttgcag tatgcgaatc
    19441 aggcgcaggt gacaaagccg cagattcaac agacacagga cgtaacccag gatactatgt
    19501 tccttttggg gagcgaagcg ctggagtcga tgattaagca cgaagcgacc cgtccgttgg
    19561 tgttctcatc aaactactat cagactcgtc aaaacctgct ggatatcgac aatcttgacg
    19621 ttgataaact tgatattcat gcttaccgct atgtaatgaa accgacgtta cctattcgtc
    19681 gcgatagccc gaagaaagca attaccttga ttctggctgt gctgctgggc ggcatggttg
    19741 gcgcggggat tgtgcttggg cgtaacgcgc tgcgtaatta caacgcgaaa taatattatt
    19801 gtgcatttaa gagaaacggg cagggtggtg acaccatgcc cgtttttttt gccggatgcg
    19861 atgctggcgc atcttatccg gcctacgtgt gttgagataa tgtgtaggca cgataagctt
    19921 gcgcatcggg caatggctcc gggtgtggca acaacatcac acctgctcag cacgccactc
    19981 actgatgccg tttacgcagg ttctcaatta ccgttgttaa atccagatcc tgatcctgca
    20041 acaacaccag caggtgatac atcaagtcag atgcctcgtt ggtcagctca aagcggtcat
    20101 gtaccgttgc tgccagtgcg gtttcaacgc cttcttcacc cactttctgc gcaatgcgtt
    20161 tggtgccgct ggcatacagt ttggcggtgt aggaggtttc cgggtcggcg gatttacgtt
    20221 ccgcgagcag ttgttccagt tgatacagga acagccactg gtgagcggta tcgccgaagc
    20281 agctgctggt gcctttgtgg caggttggcc cgatgggatt cgccagcacc agtaacgtgt
    20341 cgttgtcgca gtccggcgca atatttacta cgttgaggaa attacccgac gtttcgcctt
    20401 tggtccacag tcgctgttta gtgcgcgaga agaaggtgac tttgccgctt tcgatggttt
    20461 tgtccagagc ttccgggttc atatagccca gcattagcac ttcgccagat accgcgtgtt
    20521 gcacaatcac cggcatcagt ccgtcggttt tttcccagtc cagttcgcga cgttgttgtt
    20581 ctgttaacat atcctgatct ccacgccctg tgttgccagg tacgctttta attcaccaat
    20641 attgattatt tgtttgtgga atacggaagc agccagcgca ccgtcaacgt cggcatcgcg
    20701 gaaggcttcc aggaagtgtt ccatggtgcc cgcgccaccg gaggcaatca gcgggacgtg
    20761 gcaaacttca cgcacttttt tcagctgttc gaggtcgtaa ccgttacgca cgccgtcctg
    20821 attcatcatg ttgaggacga tttctccggc accgcgtttt tgcacttcct gcacccagtc
    20881 gagagt
//
