LOCUS       AB812044               19827 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli genes for O-antigen biosynthetic locus, partial
            sequence, strain: H320a.
ACCESSION   AB812044
VERSION     AB812044.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 19827)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..19827
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="H320a"
                     /db_xref="taxon:562"
                     /note="serogroup:O97"
     gene            287..1375
                     /gene="rmlB"
     CDS             287..1375
                     /gene="rmlB"
                     /note="O097_01"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6 dehydratase"
                     /protein_id="BAQ01427.1"
                     /translation="MKILVTGGAGFIGSAVIRHIINNTLDAVVNIDKLTYAGNLESLV
                     DIENSERYIFEQVDICDSEAIARIFACHQPDAVMHLAAESHVDRSITGPAAFIETNII
                     GTYVLLEETRKYWLSLDEARKAAFRFHHISTDEVYGDLPHPDKQIPGTALPLFTENTP
                     YAPSSPYSSSKASSDHLVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLIILNALAG
                     KQLPVYGNGEQIRDWLYVEDHARALYKVVTEGTVGETYNIGGHNERKNIEVVKTICAI
                     LDEIVTAKPKGIQRFEQLITYVADRPGHDLRYAIDASKIKRELGWVPAETFESGIRKT
                     VNWYLNNDGWWKRVIDGSYAGERLGLVD"
     gene            1386..2255
                     /gene="rmlA"
     CDS             1386..2255
                     /gene="rmlA"
                     /note="O097_02"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="BAQ01428.1"
                     /translation="MMKGIVLAGGSGTRLYPITQGVSKQLLPVYDKPMIFYPISVLML
                     AGIRDILIITTPEDMPSFKRLLGNGSQFGIRLSYEVQPSPDGLAQAFIIGEEFINNEP
                     CALVLGDNIYFGQSFGKKLETAAQLTRGAMVFGYQVLDPERFGVVEFDKSFKALSIEE
                     KPLKPKSNWAVTGLYFYDSNVVEMAKQVKPSGRGELEITTLNQMYLERGELQVELLGR
                     GFAWLDTGTHDSLVEASQFIHTIEKRQGMKVACLEEVAYRKGWLSKEQVSEQATKMAK
                     NDYGRYLRMLINE"
     gene            2278..3168
                     /gene="rmlD"
     CDS             2278..3168
                     /gene="rmlD"
                     /note="O097_03"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAQ01429.1"
                     /translation="MKILLIGKNGQVGWELQRSLSTLGELVAIDYFDTGMCGDLTDPE
                     GIAETIRLVRPDVVVNAAAHTAVDKAESERKLSQLLNADSVEVIARETARLGALVIHF
                     STDYVFNGEGEHYRLEDEEPAPLNVYGETKLAGEAAIIKYNPRHFIFRTSWVFATRGA
                     NFVKTMLRLAKEKETLSIINDQHGAPTSAELIADCTAIAIRVEHNNKSLHGTYHLVAS
                     GETTWYEYAKYVFSVAHQFNEILAVKEVKAVDTSAYPTPAKRPHNSRLANSKFQNAFL
                     VTLPDWKIGVQRVVTELLGK"
     gene            3186..3731
                     /gene="rmlC"
     CDS             3186..3731
                     /gene="rmlC"
                     /note="O097_04"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="BAQ01430.1"
                     /translation="MNVIKTEIQDVLILEPKVFGDERGFFFESFNQHVFEEAVGKKVS
                     FVQDNHSKSKKGVLRGLHYQLAPHSQGKLVRCTMGAVFDVAVDIRIGSETFGKWVGVE
                     LSAENKRQLWIPEGFAHGFVTLTDTAEFLYKATNYYAPCAERCIIWNDSQLSIAWPEI
                     NEISLSSKDVTGLPLKDSELN"
     CDS             3738..4664
                     /note="O097_05"
                     /gene="wekN"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01431.1"
                     /translation="MKHEPKIAILLCSYNGGAYIRRQLDSIISQSYSNWVLYISDDGS
                     TDETLDIVYEYKKRLGDGRVQVFSGPGQGFAWNFISLVDKVPGDFDYYAFSDQDDEWL
                     NFKLDKAVQLLITDDSIPQLYCGRTQLVDEDNCRLGLSPLFTRKPCFRNALVQSIAGG
                     NTMIFNRASKNIILKTPSNSKIISHDWWIYILVTGCGGRVIYDKQPTILYRQHQNNII
                     GANKGISARLSRLLGVIDGRYKKWIQANLDVLEEIEINFTEDNRFVLNNFIRARKSGF
                     FKRIYIFSKIKLFRQTLVGSFAFIIAIMMNKV"
     CDS             4733..5494
                     /note="O097_06"
                     /gene="wesB"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ01432.1"
                     /translation="MINIVIPMAGAGSRFAKAGYADPKPLIPINGTPMIKLVINNLKP
                     AVPHRFIFICQKEHSQKYDLQQKLKSWAPGSEVIEIDGLTEGAACTVLTAKDLINNED
                     ALMIANSDQYVDIDIDDYLRYQEEENLDGLIMTMTADDPKWSFVKIDVNNLVRDVVEK
                     VVISDEATVGIYNFKHGRDFIAAAELMIKNNLRVNNEFYVAPTYNQLINDYNSKIGIY
                     NIGSEANGMYGLGIPDDLNLFLSLPVCKKALEKSK"
     CDS             5491..6123
                     /note="O097_07"
                     /gene="wesN"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAQ01433.1"
                     /translation="MKIISHRGYWKSTEEKNKEVAFTRSFALNYGTETDVRDYLGDLV
                     ISHDIADENAITLNSFLENANKYGSEDNKITLALNIKADGLASSVSIAISKFNNLDCF
                     VFDMAVPDMRSYFEHSVPVFTRCSEVESQPVWLEKSTGIWLDAFDKEWFTSDLIITLL
                     ATGKRVCIVSSELHGRDKTRLWEMLLPLRSQPNLILCTDVPEDASEYFSR"
     CDS             6134..6751
                     /note="O097_08"
                     /gene="wesO"
                     /codon_start=1
                     /transl_table=11
                     /product="putative hydrolase"
                     /protein_id="BAQ01434.1"
                     /translation="MTIKAILFDMDGVLIDAKEWHYEALNKALDLFGMKISRFDHLTT
                     FDGLPTKKKLEMLSKERHLPRELHDFINEMKQQYTMEIVHTECKPQFIHEYALSRLKS
                     EGYKIAVCSNSIRNTVTTMMDKASLTGYIDLMISNEDVTHGKPDPEMYKLAMKTLGLK
                     PDECLIVEDNENGIKAAKGAGGNLLVVRDVYDTNYTNISSRIKAL"
     CDS             6777..7514
                     /note="O097_09"
                     /gene="wesH"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01435.1"
                     /translation="MAVNILILAAGPTTNDQRDGGYPLCLTETDGVSLIERIVENTKN
                     IENAKYSFALLEQDIEKYHLDRIVQLLAADCIVSKIPEGTKGSACTALLASSQLNGDN
                     ELLIISANELVDLDFTDVLSEFRNKKLDGGTLIFKSIHPRYSYVSLGLDELVIEAAQQ
                     KPISQHATAGVFWFARTSDFQDAAKNLIRKNASVNERFYVAPTFNELILRQMRVGVRA
                     LKLSDYKPLKTERQVNQFENSASYEKF"
     CDS             7492..7821
                     /note="O097_10"
                     /gene="wesQ"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAQ01436.1"
                     /translation="MLLMKNFKLDDMIKGWFVGGFSPTAFATEDCEVAVKKYKCGDKE
                     EAHYHKLATEITVIISGTVKMLDKEWHQGDIIVLSPGEITSFEAITDAINVVVKLPGA
                     LNDKYVV"
     gene            7964..8704
                     /gene="wzm"
     CDS             7964..8704
                     /gene="wzm"
                     /note="O097_11"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ABC transporter permease"
                     /protein_id="BAQ01437.1"
                     /translation="MLYSSLRLAIFEIQKRSLNTYAGWTWSLMNPLSQMAILYFIMTH
                     VFKSNIENILLWLISGLNCWIVIQSALLRSCQSLISRRALLQNNNISHNLLVMSDILS
                     EVIILIPFYLFAIALAIFHGVPFSNLILVPLMLLILLVFLLGLGMILATLTPILRDLP
                     YLLGIFMQIAFWLTPIAYAKSSMKGFAASIINFNPFTYFILLSQSIFMGSPVSMKLVV
                     IPAGLAIIAVSVGFMLSNAVGKKTVINL"
     gene            8701..9426
                     /gene="wzt"
     CDS             8701..9426
                     /gene="wzt"
                     /note="O097_12"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen export system, ATP-binding protein"
                     /protein_id="BAQ01438.1"
                     /translation="MKKSVEFKNVELLVPEADRPQSLKSLLLNFRKLNSKKKTILSIP
                     HFTAHDGDKICIVGRNGNGKTTFLKVLAGIYPVTRGIIWTEKKPTVVLAAGIGLEEEL
                     SVIENINLSLIIKNVKKSDIPALAESILEFCELKDDRYKQYKHLSTGFKSRLAFAIAV
                     SEKPDILILDEVLGGGDEFFMKKANAKLIETINVSSTAFIATHAPDQMQGICNRLVMI
                     EKGQILFDGAFEEGVNFYRNSYV"
     CDS             9448..10743
                     /note="O097_13"
                     /gene="wesR"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAQ01439.1"
                     /translation="MAISVVICGLVRSQEKLLTKLQNYFDWREQGRVDEIVYSTWIGE
                     IDSYSGLRKILETKNVKMIEVEEPRLVLKGGHQLHQMLAFYYGLSALKNQDQFVLKTR
                     VDLADNHASMLHEFEFGTSEANDFAGVGIKKRILVEYAQMLYPFLCGDAQFFGHINDL
                     KKLVNLSAEMELLYNRLAVEQTFFFNPFKELALFKQHFYWNLPHISEISDRRNEQIAD
                     VITNESIVRAIQGWWFILDNYFKIGWGPTLPDTIPFTSIQDAFKYKGHDKLIGDDFSD
                     VIVNQSFVTSLIGLFTEEEANSILEDVSNNENYNMLAIPKNVFNDYQGFLKKFSDLPA
                     AKAVCCQNNRLIISGATQHFFVKDENDSASKRYHEQITALRRENEILRKTQNINFSNS
                     LIHRVLNRHLSRKTIDFLKYKCPQLTDFYARHFMRKREK"
     CDS             10745..11773
                     /note="O097_14"
                     /gene="wesS"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ01440.1"
                     /translation="MRLQGYFEILRLTIQFQEYKNKTDFIINHPWRLLLLALLKIIRR
                     FHNLLNRGAMKKLIISNKPNGVYVDDSFLRIEYNNGNYEVIIENVNDVTTPVVNNIKS
                     TALQTFSSNRKVVFVHAFYHEEAIYIFNQLSMFFDYDIIISSPHADIINRAKEKFGSE
                     RVIGLITPNHGRDVLPFLICLKFINVENYSHFVKLHTKKSKHLRDKGRWFRLNVEFLI
                     GNKSVTDKIFQLMPDNAPIILGESVLEIQDHLENNVHWLAFLLAKDPSCIDSKFIPGT
                     MFLGTGSFLRLVKSLNLHRYKIEKEAGQLDGCCVHAMERYFGYLASVHGGNCDALEAF
                     VGKEEAKL"
     CDS             11770..13422
                     /note="O097_15"
                     /gene="wesT"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAQ01441.1"
                     /translation="MKKTILINGAVRDIEEFVLIIDCLLEQRKKSEEKIEIIISTWHE
                     DINKNLQLFRWIASNDIKVVGSAGIDSGGPANIFRQWRTLEAGLSIVSSDSLILKGRT
                     DKFLLRKDVIEAFVKAEGSDPALQMAIKQDKLAVEHISLSLPFMAKDMIYIGTVTAIR
                     KIMHYSVRTKYVADHIFHGIGPECFLWLESCSSDQELMQLIQKIDFRFISNELMKNNC
                     IFEYDWSQIKPQICLLYSKWYHSFDSNFTFLSDIIKCHKSPSWVINEGLYKYQTGDRE
                     DYERLRFILESVTPTSLLNCASELCFLNSTDTFTLESNSDNSYLEWKPELPFLEDIDR
                     IRNDYSREYSDIVLLRSKLIQRMLVSQNPDPKKLTQALKWNIRQRDNETLNMVYNWMM
                     SADDNIKYVSHDDRLFVLERILDSFTFIADNVAIENTIEILKDYFKKSPQLSVRVAES
                     YFRKGKLYYSLYWFWLSYKGLPGHLGVNHGLGCTLLDLGFPRLALKYLRQANAIQPQD
                     QTASFTLIRCLARCNKKSEAKILMNNLSGHLRVEAERILNAD"
     CDS             13391..14851
                     /note="O097_16"
                     /gene="wesU"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAQ01442.1"
                     /translation="MKQRGSSMLIKMIRKKRWLKKFDGALRAAYEASNYLNHYSYQWF
                     SENVYSLALGLDSAIDFDEEFYLSHNADIARAVKNGGLCCGYVHFCTLGKYELRVWSS
                     KKIYEIRPGGPILGAGLAEPKNIFPLPHYTPDLSALPESSEKSLVILIPFLVDDLFFA
                     GYTSFFNDMTLIFPLFSDVKVIVSNAHYNEHLLDKYGGNIQVLPFSDISLLTVKPTLV
                     YCFDTETFFQAKQVFGELKRVVYYCQDYESGFYPYGSMYARSQSAIYLSKNIVFSTGI
                     LASSIESKGLLGDDVNIYITSPKIEPFSVKNVKSKKLFFYYRPEFFNSRNMPELILRT
                     VIDFCQKHTGYEIYLVGAVGTSFSQNINGTNVVILSKLAKDEYLDLISSCDAVVALIY
                     SDHPGVIAYQAAASGIPTVTNTFEIRNADFIHSISSNLVPFDPVRDSLVDKLEFALSM
                     PKGNCDFNSAMYEQRSLLSFYDFNSKIIGNDRSYTR"
     CDS             14848..15756
                     /note="O097_17"
                     /gene="wesV"
                     /codon_start=1
                     /transl_table=11
                     /product="putative methyltransferase"
                     /protein_id="BAQ01443.1"
                     /translation="MKTSDNKNDFYPSAYSLRFTPARLSKAIDWHGHLSFAAWLMELV
                     RPEILVELGVFRGDSLSTFSQASRDLNIKCEITGVDSWGGDNTTGAYGEEVYSEVKDY
                     FSSSFPNTKLYRALFDEALSEFSDDSVNVLHIDGCHHYDAVKHDYETWLPKVSTENGI
                     ILFHDTNVVAHGFGSKQFWEEINSTYPSFSFNHSNGLGVLLVGKRQPNEFIALSQDER
                     FLDKVRSIYELSGNMFIHKAKEQWWKDEADKHAAYVNHLTGDVGKQIADTINHHFVNH
                     LTAHRQTGVFSNNNYAKRLVKKIFHR"
     gene            15936..17342
                     /gene="gnd"
     CDS             15936..17342
                     /gene="gnd"
                     /note="O097_18"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ01444.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVVA
                     ENPGKKLVPHYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELATT
                     FTEWNEGELSSYLIDITKDIFTKKDEDGKYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLTGPQAKLAGDKAEFVEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENAGIANLLLAPY
                     FKNIADEYQQALRDVVAYAVQNGIPVPTFSAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRTDKEGVFHTEWLD"
     gene            17546..18712
                     /gene="ugd"
     CDS             17546..18712
                     /gene="ugd"
                     /note="O097_19"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ01445.1"
                     /translation="MKITISGTGYVGLSNGILIAQHHEVVALDIVQAKVDMLNQKQSP
                     IVDKEIEEYLATKPLNFRATTDKHDAYRDADYVIIATPTDYDPKTNYFNTSSVESVIR
                     DVVEINPNAVMVIKSTIPVGFTNSIKEKLGIDNIFFSPEFLREGRALYDNLHPSRIVI
                     GERSERAERFAALLQEGAVKKDIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNSRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYASVPNNIVGAI
                     VDANRTRKDFIADSILARKPKVVGVYRLVMKSGSDNFRASSIQGIMKRIKAKGIPVIV
                     YEPAMKEDEFFNSRVVRDLDAFKQEADVIISNRMAEELADVKEKVYTRDLFGND"
     gene            complement(18769..19368)
                     /gene="hisI"
     CDS             complement(18769..19368)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ01446.1"
                     /translation="MLTEQLDWQKTDGLMPAIIQHAVSGEVLMLGYMNEEALTKTQET
                     GKVTFFSRTKQRLWTKGETSGHFLNVVSIAPDCDNDTLLVLVNPIGPTCHKGTSSCFG
                     DTSHQWLFLYQLEQLLAERKNADPASSYTAKLYASGTKRIAQKVGEEGVETALAATVH
                     DKFELKNEASDLMYHLLVLLQDQELDLTAVIENLRERHK"
BASE COUNT     5810 a   3660 c   4317 g   6040 t
ORIGIN
        1 acactaaatc agtaagttgg cagcatcacc ggataaatag gtatgatgat tgtaagattt
       61 ttccttgttt tcaggtgcat ttaagaagaa aatagcttgc gaggtcatgg tcagaattct
      121 gccatatctt gctccgacac ccttggttgc taacattatt ggtcgttgca cacagtgtac
      181 tggttgctgt agagctaggg gcggtagcat gtctgaaatt tgtctcgcgc acttgtctat
      241 gtttttatac gattatcaag tcaaatagta atagtggaaa attcacgtga aaatactggt
      301 tacaggtgga gcaggattta ttgggtctgc agttattcgt catattatta ataatactct
      361 ggatgctgtg gtcaatattg ataaattaac ctatgcgggt aatcttgaat ctctggtcga
      421 tattgaaaat agtgaacgat atatttttga acaagtggac atctgtgaca gcgaggcgat
      481 agctcgtatc tttgcctgcc accaacctga tgccgtgatg catcttgctg ctgagagcca
      541 tgttgaccgt tctattaccg ggccagctgc atttattgag acgaatatca ttggtacgta
      601 tgtgctcctg gaagaaactc gcaagtactg gttatctctg gatgaggcgc gtaaagctgc
      661 gttccgcttc catcatatct caaccgatga ggtgtatggc gacttgccgc acccggataa
      721 gcaaatccca ggtactgcgt tgccgttgtt taccgaaaat acaccatatg caccaagtag
      781 cccttattcg tcgtctaaag catcaagtga ccatttagtt cgtgcctggc gacggactta
      841 tgggttgcca acgatcgtga ccaactgttc taacaactac ggcccttatc attttcctga
      901 gaagttaatc ccgctaatta ttctcaatgc gcttgcgggc aaacaactgc cggtttacgg
      961 caatggcgag caaattcgtg attggctcta tgttgaggat catgcgcggg cactgtataa
     1021 agttgtgacg gagggaactg tcggggaaac gtataatatt ggtggccata atgaacgtaa
     1081 aaatattgaa gttgttaaaa ctatttgcgc cattcttgat gagatagtca ctgctaaacc
     1141 gaaaggtatt caacgttttg aacaacttat cacctacgtt gccgatcgcc cggggcatga
     1201 tttgcgttat gcaattgatg ccagcaaaat caaacgtgaa ttaggctggg tgcctgctga
     1261 gacatttgaa tctggtatcc gtaaaacagt taactggtat ttgaataatg acggctggtg
     1321 gaaacgtgta atagatggct cctacgcggg agaacgttta gggctggtgg attaattaag
     1381 gaataatgat gaaaggtatt gtgcttgctg ggggatctgg aactcgccta tatccgatta
     1441 cgcagggggt atccaagcag ttgctgccag tttacgacaa gccaatgatt ttctatccga
     1501 tatcggttct gatgttggct ggaattcgtg atattttaat tataacaact cccgaagata
     1561 tgccttcctt taaacgtctg ttgggtaacg gatcgcagtt tggcattcgc ctctcctatg
     1621 aagtgcagcc atctccggat ggcttggccc aggcatttat tattggtgag gagttcatca
     1681 ataacgaacc gtgcgcactg gtattggggg ataatattta tttcggtcag agctttggta
     1741 aaaagctcga aaccgcagcg caattgaccc gtggggcaat ggtttttggt tatcaggtgt
     1801 tggatcctga acgttttggt gtggttgagt ttgataagag tttcaaagcg ctttctattg
     1861 aggaaaaacc gctcaaaccg aaatctaact gggcagtaac aggactttat ttctatgaca
     1921 gtaatgttgt ggaaatggca aaacaggtta aaccttctgg aagaggtgaa ttggagatta
     1981 ctacgctgaa ccaaatgtat cttgagcgcg gtgagctgca ggtagaattg ctaggacgtg
     2041 gttttgcttg gttggataca ggtactcatg acagccttgt agaagcatcg cagtttattc
     2101 ataccattga gaagcgtcag gggatgaaag ttgcatgctt ggaagaagtc gcttaccgta
     2161 aaggatggtt gagcaaagag caagtttccg agcaggcgac gaaaatggct aaaaacgatt
     2221 atggccgcta tttgcgcatg ttaatcaatg aataactcac cataaagaaa atcttgtatg
     2281 aaaattttgc tgattggaaa aaatgggcaa gttggttggg aacttcagcg ctctctttca
     2341 acattaggcg agttagttgc aatagattat ttcgatactg gtatgtgtgg tgatctaact
     2401 gatcctgagg gtattgctga gactatacgt cttgtaaggc ctgatgttgt tgtcaatgca
     2461 gcggctcata cagcagtgga taaagctgag agtgaaagaa aactatctca attgctaaat
     2521 gccgatagcg ttgaagtaat tgctcgggag accgcaagat taggtgcctt ggttattcat
     2581 ttttctactg actacgtttt caatggggag ggggaacact atcgtcttga agatgaagag
     2641 cctgctccgt tgaatgtgta cggagaaact aaattagcgg gggaagcagc tataatcaaa
     2701 tataatcctc gtcattttat tttccgcaca agttgggtct ttgctacacg tggtgctaat
     2761 tttgttaaga caatgctgcg gcttgcaaag gaaaaagaaa ccttgtcaat catcaacgat
     2821 caacatggtg cgcctactag cgcagaactt attgccgact gcacagcaat agccatccga
     2881 gttgagcata ataataaatc attgcatggt acataccatt tagtggcaag tggagagact
     2941 acttggtatg aatatgctaa atatgtattt tctgtagctc atcagtttaa tgaaattttg
     3001 gctgttaaag aggttaaggc tgtagatacc tctgcgtatc cgacacctgc aaaaaggcca
     3061 cataattctc gccttgcaaa ttcgaagttt caaaatgctt ttttggtaac attacctgat
     3121 tggaaaattg gtgtacaaag agttgttact gaactgctgg gaaaataagc taggagagta
     3181 ctaaaatgaa tgtaatcaaa acagaaattc aagatgtatt aattttagaa cctaaagttt
     3241 ttggtgatga acgtggtttc ttctttgaaa gtttcaatca gcatgttttc gaagaggcgg
     3301 ttgggaaaaa agtttctttc gtccaggata atcattcaaa atcaaaaaaa ggggtcttga
     3361 gaggacttca ttatcaattg gcaccacatt cacagggtaa attagttcgc tgtacaatgg
     3421 gggccgtatt tgatgtggca gtagatattc gaattgggtc tgaaacattc ggcaagtggg
     3481 ttggggtaga attaagtgca gagaataagc gtcaattgtg gattcctgaa ggcttcgctc
     3541 atgggtttgt cacattaact gatacggctg aatttttgta taaagctaca aattattatg
     3601 cgccatgtgc cgagcgttgc ataatctgga acgactctca actttctatt gcatggccag
     3661 aaataaatga aatttcctta tcttctaaag atgtgactgg cctgccatta aaagattccg
     3721 agctcaatta ataaaatatg aaacatgaac caaaaatagc aatattgtta tgtagttata
     3781 atggtggcgc ttatattaga cggcaacttg attcaattat aagtcaatct tatagtaatt
     3841 gggtgctgta tatatcagat gatggttcaa ccgatgagac tttggacatt gtctacgagt
     3901 acaaaaaacg cttaggtgat ggacgtgtac aggtattttc tggtccaggg cagggatttg
     3961 catggaactt tatttcactt gtcgataaag tcccgggaga ttttgattat tatgccttta
     4021 gcgatcaaga cgatgagtgg ttgaacttta aacttgataa agcagttcaa ctcttaatta
     4081 ctgatgacag tattccacag ttatattgcg ggcgtacaca attagttgac gaggacaatt
     4141 gtagattagg gctttcgcca ctttttacga gaaaaccttg cttccggaat gcattagtac
     4201 aaagcattgc tggtggcaat acaatgatat ttaatagggc ctcaaaaaat attattttaa
     4261 aaacaccgtc aaattcaaaa attatatcgc atgactggtg gatctatata ttagtcactg
     4321 gttgtggtgg tagagttata tatgataaac aaccaacaat tctctaccgt cagcatcaaa
     4381 ataatattat tggggccaac aagggtattt cagcacggct gagtcgtttg cttggcgtta
     4441 tagacggacg ctataaaaaa tggatacaag caaatcttga tgttctagaa gaaatagaaa
     4501 taaattttac ggaagataat cgattcgttt taaataattt tatacgtgct cgtaaatctg
     4561 gtttcttcaa aagaatatac atcttttcca aaattaaatt attccgtcaa acattggttg
     4621 gcagttttgc ttttataata gcaataatga tgaacaaagt ataattattt atatggagat
     4681 ggttgtctta aatgacagtc gtcccttact tttatataac gataggtgaa aaatgattaa
     4741 tattgttatt cctatggctg gcgccggaag ccgttttgcg aaagctggtt atgctgatcc
     4801 taaaccatta atacctatca atggtacgcc aatgatcaaa ttggttataa ataatttaaa
     4861 gcccgcagtc cctcatcgat ttatttttat ctgtcaaaaa gaacattcac aaaaatatga
     4921 tttgcaacaa aaattgaagt catgggctcc tggttcggaa gttatagaaa ttgatggttt
     4981 gactgaaggt gctgcatgta ccgtacttac ggcgaaagat ttaattaata acgaagatgc
     5041 tttaatgatt gctaatagcg atcaatatgt tgatatcgat attgatgatt acttgagata
     5101 ccaggaggaa gaaaatttag atggtctgat tatgactatg actgctgatg atcctaaatg
     5161 gtctttcgta aaaatagatg ttaataattt agttcgcgat gttgttgaaa aagtcgttat
     5221 ttctgatgag gcgacagtag gtatctataa tttcaaacat ggccgtgact ttattgctgc
     5281 cgctgagttg atgattaaga ataatcttcg ggtaaacaac gagttttatg ttgcaccaac
     5341 atataatcaa ttaattaatg attataactc caagattgga atctataata ttggctctga
     5401 agctaatggt atgtatgggc ttggaattcc tgatgattta aatttatttt tatcgctacc
     5461 tgtatgcaaa aaagcattgg agaaaagtaa atgaaaatta tttcccatag aggttattgg
     5521 aaaagtacgg aagagaaaaa taaagaggta gcatttactc gttcttttgc tctaaattat
     5581 ggtacggaaa cagatgttcg tgattacctt ggggatttag tcatttcgca tgatattgct
     5641 gatgaaaatg caataacttt aaattcattt cttgaaaatg cgaacaaata tggttcagaa
     5701 gataataaaa tcacattagc tcttaatata aaagcggatg gtctggcaag tagcgtctca
     5761 atagcaatta gcaaatttaa taatctcgac tgctttgtat ttgatatggc agtgccagat
     5821 atgcgaagct actttgaaca ctcggtacca gtcttcactc ggtgtagcga ggttgaatca
     5881 caacctgtat ggctcgaaaa atctactggc atttggttag acgctttcga taaggaatgg
     5941 tttacctctg accttatcat tacgttatta gcgactggta agcgggtatg tatcgtctca
     6001 tcagagttac atgggcgtga taaaaccaga ttgtgggaaa tgctgttacc tttaagatca
     6061 caacccaatt tgattctttg cacagatgtt cctgaagacg caagtgagta tttttcgcga
     6121 taatgaggcg agtatgacta ttaaagcaat tttatttgat atggatggtg tgcttatcga
     6181 tgctaaagaa tggcattatg aagctttaaa taaagcactt gatttgtttg gaatgaaaat
     6241 atcccgtttt gaccatctaa caacttttga tggattgcct accaaaaaaa aattagaaat
     6301 gcttagtaaa gagagacatt taccgaggga gttgcatgat tttattaatg agatgaaaca
     6361 acagtataca atggaaattg ttcatactga atgtaaacct caatttattc atgaatatgc
     6421 tctttctaga cttaaatcag aaggttataa gatcgccgta tgttctaatt ctatcagaaa
     6481 tacagtgaca acaatgatgg ataaggcatc tttaactggt tatattgatt taatgatttc
     6541 gaatgaggac gtaactcatg gtaaaccaga tcctgaaatg tataagctgg ctatgaaaac
     6601 cctaggtctg aaacctgatg agtgtctcat tgttgaagat aatgaaaacg gtatcaaagc
     6661 agccaaagga gcaggtggta acttactagt tgtccgtgat gtgtatgata caaactatac
     6721 aaacatctct tcgcggataa aggcgttgta atccgattct gattaggaga aatatcatgg
     6781 cggttaatat acttattctt gctgcgggtc caacaactaa cgatcagcgg gatggcgggt
     6841 atcctctgtg tttgacagaa acagatggcg tatctttaat tgagaggata gttgaaaata
     6901 ctaagaacat tgagaatgca aaatatagtt ttgcattact agaacaggat atagaaaaat
     6961 atcatttgga tcgtattgtc caattactcg ctgcagactg tattgtgtcg aaaattccgg
     7021 agggaactaa aggatctgct tgtacagcat tattagcatc gagccaattg aatggtgata
     7081 acgaactact aatcatcagt gcgaacgaac ttgttgatct tgattttact gatgtactca
     7141 gcgaatttag aaataagaag cttgacggag ggactcttat atttaaatca atacatcctc
     7201 gctattcata tgtctcctta ggcttggatg agcttgtgat tgaagctgcg cagcaaaaac
     7261 cgattagtca gcacgcgacc gctggtgttt tttggtttgc acgtacttct gattttcaag
     7321 atgctgctaa aaatcttatc aggaaaaatg caagtgtaaa tgaacgattt tatgttgcac
     7381 caacatttaa tgaactgatt cttcgtcaga tgcgtgtagg agttcgtgca ttaaagctta
     7441 gcgattacaa gcccctcaaa actgaaagac aagttaacca attcgaaaat agtgcttctt
     7501 atgaaaaatt ttaaacttga tgatatgatt aaaggatggt ttgtaggtgg tttttcacca
     7561 acagcctttg ctactgaaga ctgtgaagtt gcagttaaga aatacaaatg tggtgataaa
     7621 gaagaagctc attatcataa gctagctact gaaattactg taataatcag cggtactgtt
     7681 aagatgttag ataaagaatg gcatcaagga gatattattg tattgtctcc tggtgagatt
     7741 acttcttttg aggcaattac tgacgctatt aatgtagtag tgaaattacc tggtgcattg
     7801 aacgataaat acgtagttta attttattat ctatttgtca agttagcttt ctttatatta
     7861 aaaagaaagt tcctatcgct gcattttaaa ttaaatgtgc acactgtaat tggtaaagag
     7921 atatcgtttg taaatatgat atcaattgct aaggtattag ataatgttat atagtagttt
     7981 gcggcttgcg atatttgaga tacaaaaaag atctctgaac acttatgctg gttggacttg
     8041 gagtctaatg aatccattat cgcaaatggc cattttgtat tttattatga cgcatgtttt
     8101 caaaagtaat atcgaaaaca ttttgctttg gctcataagt ggacttaact gttggatcgt
     8161 tattcagagt gctctattga gaagttgtca gagccttatc tccagaagag cacttttgca
     8221 aaataataat atatcacata atcttcttgt tatgtccgat attctctcag aagttattat
     8281 tttaattcct ttttacttat tcgcaatagc attagcaatt tttcatggtg taccattctc
     8341 taatctaatc ttagttccct taatgcttct aattttgctc gtattccttt tgggtttagg
     8401 aatgatactt gcaacattaa ctcctatatt acgtgattta ccttacctac tgggaatctt
     8461 catgcagata gcattttggt taacaccaat tgcttatgct aaatcctcaa tgaaaggttt
     8521 tgcagcatca attattaatt tcaatccttt tacctatttt attcttctat cgcaatccat
     8581 tttcatgggc agcccggtct caatgaaatt ggtcgttata ccagctggcc tagctattat
     8641 cgccgtttca gtcggtttta tgctttcaaa tgcagtaggt aaaaagacgg taattaattt
     8701 atgaaaaaat ctgttgaatt taaaaacgtt gaattacttg tacccgaggc agatcgtcca
     8761 cagtcactta aaagcttgtt acttaatttc agaaaactga atagcaagaa aaaaacgatt
     8821 ttatcaatac cacatttcac tgcccatgat ggcgataaaa tttgtatcgt agggcgtaat
     8881 ggtaatggta aaacaacttt cttgaaggtc ttggctggca tttatcctgt gacgagagga
     8941 attatttgga ctgaaaaaaa accgacggta gttttagccg cggggatagg tctcgaggaa
     9001 gaactgagtg tcattgaaaa tatcaaccta tcactgataa ttaaaaatgt gaagaaatct
     9061 gatattcctg ctcttgctga atcgatatta gaattttgtg agctaaaaga tgatcgctat
     9121 aagcaatata agcacttatc gactggtttt aaaagtcgat tagcatttgc cattgcagtg
     9181 agtgagaaac ctgatattct cattcttgat gaagtattag gcgggggaga tgagtttttc
     9241 atgaagaagg ctaatgcaaa gctaatagaa acaattaatg tgtcttccac tgcatttatt
     9301 gccactcatg caccagacca aatgcaaggg atttgtaatc gtttggtcat gatcgaaaaa
     9361 ggacaaattc tctttgatgg cgcttttgaa gagggcgtta atttttatag aaatagttac
     9421 gtataaatat aaatggaata aataaccatg gccatttctg ttgttatctg cggcttagta
     9481 agaagccagg aaaaattact tactaaactt caaaattatt tcgactggcg cgaacaaggt
     9541 agagttgatg agattgtcta ttctacttgg attggcgaaa ttgatagtta ttcaggcctt
     9601 agaaaaattc ttgagaccaa aaatgttaag atgatagaag ttgaagaacc acgcttagtt
     9661 cttaaaggtg gacatcaact tcaccaaatg ctggctttct attacggttt aagcgcatta
     9721 aagaatcaag atcagtttgt tttaaaaact cgagtagacc ttgctgataa tcatgcctcg
     9781 atgttgcatg agtttgaatt tggcacatct gaagcaaacg actttgcagg tgtaggtata
     9841 aaaaaaagaa ttcttgttga atatgcgcag atgctttatc catttttatg tggtgatgca
     9901 caattttttg ggcatattaa tgatctcaaa aaactggtta acttgtcagc tgaaatggag
     9961 ttgctttata atcgtttagc agtggagcaa actttctttt ttaacccatt taaagaatta
    10021 gctctgttca aacaacattt ctattggaat ctgccacata ttagtgaaat ttctgatcgc
    10081 cgcaatgaac aaattgcaga tgttatcact aacgaaagta tagttcgggc gattcaagga
    10141 tggtggttta ttcttgataa ttacttcaag attggttggg ggccaacact acccgacact
    10201 atcccgttca catctataca ggatgcgttt aagtataaag gccatgataa gcttattggt
    10261 gatgatttca gcgatgtgat tgttaaccaa agctttgtga cttctttgat tggtcttttt
    10321 acggaagaag aagctaactc aatattagag gacgtaagca ataatgaaaa ctacaacatg
    10381 cttgctatcc caaaaaatgt ttttaatgat tatcaaggat tcctgaaaaa gttcagtgat
    10441 ctccctgcag cgaaggccgt gtgttgtcaa aataataggc tcattatttc tggtgctacg
    10501 caacatttct ttgtaaaaga tgaaaatgac tctgccagta agcgttatca tgaacaaatt
    10561 acagcattac gtcgtgaaaa cgagattcta aggaaaacac aaaatatcaa tttcagtaac
    10621 tcactcatac accgggtact taatagacat ctatcgcgta aaacaattga ttttcttaag
    10681 tataagtgtc ctcagttaac tgacttttat gcccgtcatt tcatgaggaa gagagaaaaa
    10741 taatatgcgt cttcaagggt attttgaaat attacgattg actattcaat ttcaggaata
    10801 taaaaataaa acggacttta ttattaatca tccgtggcga ttattgctgc tcgcacttct
    10861 taaaattatt agacgttttc ataacctcct aaatagaggt gcgatgaaga agttgatcat
    10921 ttcaaataaa cctaacgggg tctatgttga tgattctttt cttcgtattg aatacaataa
    10981 tgggaactat gaagttatta tagaaaatgt aaatgacgtc acaactcctg tggtcaataa
    11041 tattaaatcc acagcgttgc aaacattttc tagtaatagg aaagtcgttt ttgttcatgc
    11101 tttctatcat gaagaagcta tatatatttt taatcagctt tcaatgttct tcgactatga
    11161 tattattatt tcatcaccac atgctgatat tattaatcgc gcaaaagaaa aatttggctc
    11221 tgaacgagta attggactta taactcctaa tcatggccga gatgttttac cttttctaat
    11281 ttgtttaaag tttattaatg tagaaaatta tagccacttc gttaagttac ataccaaaaa
    11341 atccaagcat cttagagaca agggacgttg gtttagactt aacgttgaat ttttaattgg
    11401 taataaaagt gtcactgata aaatctttca gttaatgcct gataatgccc ctataattct
    11461 tggtgaatca gtattggaaa ttcaggacca tcttgaaaat aatgttcatt ggctagcatt
    11521 tttattagct aaagatccct cctgcattga tagcaaattt attcctggaa ctatgttcct
    11581 tggcactgga agttttttac gtcttgttaa atctttaaac ttacatcgtt acaagataga
    11641 gaaagaggca gggcaacttg atggatgctg tgtgcatgcc atggaaagat atttcggcta
    11701 tttagcgagt gtgcatggtg gaaattgcga tgcgcttgag gcctttgtgg ggaaagaaga
    11761 ggcgaaacta tgaaaaaaac aattttaatt aatggtgcgg tgcgcgacat tgaagagttt
    11821 gttttaataa ttgattgtct cctggaacaa aggaaaaaaa gcgaagaaaa aatcgaaatc
    11881 atcatttcta cttggcatga agatatcaat aaaaatttac aacttttccg atggattgcg
    11941 tcgaatgata ttaaagttgt tgggagcgca ggcattgatt ctggaggacc tgctaacata
    12001 tttcgccagt ggcgtacact tgaagctggc ttaagcattg tctcatcgga ttctttgatt
    12061 cttaaaggac gtactgataa atttttatta cgtaaagatg taatcgaagc ttttgtcaaa
    12121 gcagaaggaa gtgatcccgc tttgcaaatg gcaataaaac aagataaact ggctgtagag
    12181 catatttctt taagtcttcc gttcatggct aaagatatga tctatatagg gacagtaaca
    12241 gcgatcagaa aaatcatgca ctattcggta agaacaaagt atgtcgctga ccatatattt
    12301 catggaattg gtcctgaatg tttcctttgg cttgaatcat gtagttctga ccaggagtta
    12361 atgcagttaa tacaaaaaat tgactttcgg tttatctcta atgaattaat gaaaaataat
    12421 tgtatatttg agtatgattg gtctcaaatc aaaccacaga tttgcctgct ttattcaaaa
    12481 tggtatcatt cgtttgatag taattttaca tttttgtcag atataattaa atgccacaaa
    12541 tctccttctt gggtaataaa cgaaggtcta tataagtatc agactgggga tcgtgaggat
    12601 tatgaacggc tgcgctttat tcttgaaagt gttacgccga catcgcttct taattgtgct
    12661 tctgagctat gctttttaaa ttctactgac acctttaccc ttgaaagtaa tagtgataac
    12721 tcttatctgg agtggaaacc tgaattacct ttcttggaag atattgatag aataagaaat
    12781 gactattctc gggaatattc tgatatcgtc ttgctaagaa gcaaattgat tcagagaatg
    12841 ctagtgtcac agaatccaga tcctaaaaaa ctaactcaag cccttaaatg gaatattagg
    12901 cagcgtgaca atgagacttt aaatatggtc tataactgga tgatgtctgc agacgataat
    12961 ataaagtatg tatcacacga tgaccgtctt tttgttcttg aaagaatatt ggattctttt
    13021 acatttattg ctgacaatgt cgctattgaa aacacgatag aaatattaaa ggattatttt
    13081 aaaaagtctc ctcaactttc cgttcgtgtt gctgagagtt attttagaaa gggtaagtta
    13141 tattattcat tatactggtt ctggctgagt tataaaggct tgcctggtca tttgggtgtc
    13201 aatcatggtt taggctgcac actacttgat ttaggctttc ctagacttgc cttaaaatac
    13261 ttgcgtcaag ctaatgcaat tcaaccgcaa gaccaaactg cttctttcac acttattcgc
    13321 tgcttggcta gatgtaataa gaaatcagaa gcaaaaatat taatgaataa tctttccggt
    13381 catttacggg ttgaagcaga gaggatcctc aatgctgatt aaaatgataa gaaaaaagag
    13441 atggttaaaa aaattcgatg gtgctttacg tgctgcttat gaggcttcga attatttaaa
    13501 ccactattct taccaatggt tttccgaaaa tgtatattcg ttggcactgg gccttgactc
    13561 agcaatagat tttgatgagg aattttatct tagtcacaat gctgatatcg ctcgcgcagt
    13621 aaaaaatggt ggcctttgtt gtggttacgt acatttttgc acccttggaa aatatgagtt
    13681 aagggtatgg agttccaaaa aaatatatga gattagacca ggtggtccta tattaggtgc
    13741 cggtttggca gagcctaaaa atatttttcc attacctcac tatacacctg atcttagtgc
    13801 actgcctgag tcatcagaga aatctctagt cattctcatt ccttttttag ttgacgacct
    13861 tttcttcgct ggttatacga gtttctttaa tgatatgact cttattttcc ctcttttttc
    13921 tgacgttaaa gtcatagtga gtaatgctca ttataatgag catttacttg ataaatatgg
    13981 gggtaacatt caggtccttc ctttctctga tatttcactg ttaacagtga aaccaacttt
    14041 ggtatattgc ttcgatacag agaccttctt ccaggcaaag caggtgttcg gtgagcttaa
    14101 gagagtggtt tattattgtc aggattatga atccggattt tatccatacg ggtcaatgta
    14161 tgccagaagt cagtccgcta tctatttaag taaaaacatt gttttttcga ctggtatact
    14221 tgcaagttct atcgagagta aaggattgct tggagatgat gtaaatattt atataacgtc
    14281 tccaaaaata gaaccttttt cggttaaaaa tgttaagagt aagaagcttt ttttctatta
    14341 tcgacctgag tttttcaata gtagaaatat gccggagttg atattacgaa cagttattga
    14401 tttttgccaa aagcatactg gatatgaaat ttatcttgtt ggtgctgtcg gtacatcatt
    14461 ctcgcaaaat atcaacggaa ctaatgttgt tattcttagt aaactagcca aagatgagta
    14521 tcttgattta atttcatcat gtgatgctgt agttgcgctg atatattcag accatcccgg
    14581 tgttattgcg tatcaagctg ccgcctcagg aatcccgaca gtaacaaaca catttgaaat
    14641 tcgtaatgct gattttattc attcaatatc ctctaatttg gtgccttttg accctgtcag
    14701 agattcattg gtcgataaat tagagtttgc tctttcgatg ccgaaaggaa actgtgattt
    14761 taattcggcg atgtacgagc aaaggagtct attaagcttt tatgacttca attcaaaaat
    14821 tataggaaat gacaggagct atactagatg aaaacatctg ataataaaaa tgatttctat
    14881 ccctctgctt acagtttacg ttttacaccg gcacgtctca gtaaagctat tgactggcat
    14941 gggcatctat catttgctgc atggctcatg gaactcgtcc gccctgaaat attagttgag
    15001 ttaggtgtgt ttcgcggaga tagtctatcg actttctctc aggcatcccg agatctgaat
    15061 attaaatgtg agattactgg tgttgactct tggggagggg ataacacaac tggagcttat
    15121 ggcgaagaag tctattccga ggttaaagat tatttctcat catcttttcc taatacaaaa
    15181 ttgtatcgtg cattgttcga tgaggcttta tctgaatttt ctgatgattc tgttaatgtt
    15241 ctgcacattg atggttgcca tcactatgac gcggtaaagc atgattacga gacttggctc
    15301 ccgaaagtct caactgagaa tggtattatt ctatttcatg ataccaatgt tgttgctcat
    15361 gggtttggtt ctaagcaatt ttgggaagaa attaatagca cctatccttc ctttagtttc
    15421 aatcattcta atggattagg tgttctttta gtcggcaaaa gacagcctaa tgagttcatt
    15481 gcactgtctc aggatgaaag attccttgac aaagttaggt ctatttatga attatcaggt
    15541 aatatgttta ttcataaggc taaagaacaa tggtggaaag atgaagcaga taaacatgct
    15601 gcatatgtta atcatttaac aggtgatgtt gggaaacaaa tcgctgatac gataaatcat
    15661 cattttgtta accaccttac tgctcatcga caaactggtg tattctcaaa taataattat
    15721 gcaaaacggt tggtgaaaaa aatatttcac agataaccat aaggtattaa tggcatttta
    15781 ttgattatct gtgttgcttt agtattgact aatgtgtgtt ttgttttttt acttacttta
    15841 gacttttata tgtaaaaact tggaggggat aataatataa aaaccctcca gaatgtttta
    15901 tcatgagtgt tgttcacacc tgacaggagt acataatgtc caagcaacaa atcggcgtag
    15961 tcggtatggc tgtgatgggg cgcaacctgg cgctcaacat cgaaagccgt ggttataccg
    16021 tctctatctt caaccgctcc cgtgaaaaaa ccgaagaagt tgtcgctgag aatccaggca
    16081 aaaagctggt tcctcactac acggtcaagg agttcgtcga gtctcttgag accccacgtc
    16141 gtatcctgtt aatggtgaaa gctggcgcgg gcaccgatgc tgccatcgat tccctgaaac
    16201 cgtaccttga taaaggcgac atcatcattg atggtggtaa caccttcttc caggacacca
    16261 ttcgccgtaa ccgtgagctg tcagctgaag gctttaactt catcggtacc ggcgtatccg
    16321 gtggtgaaga gggcgcgctg aaggggccat ccatcatgcc aggcggccag aaagaagcgt
    16381 atgagctggt tgcgcctatc ctgaccaaaa ttgccgctgt ggcggaagac ggcgaacctt
    16441 gtgtaaccta catcggcgct gacggtgcgg gccattatgt gaaaatggtg cacaacggta
    16501 tcgaatacgg cgacatgcag ctgattgctg aagcctattc tctgctgaaa ggcggcctga
    16561 acctgtctaa cgaagagctg gcaaccacct tcaccgagtg gaatgaaggc gagctgagca
    16621 gctacctgat cgacatcacc aaagacatct tcaccaaaaa agatgaagac ggtaaatacc
    16681 tggttgatgt gatcctcgac gaagcggcga acaaaggcac cggtaaatgg actagccaga
    16741 gctctctgga cctcggcgaa ccgctgtcgc tgatcactga atccgttttc gcgcgctaca
    16801 tctcctccct gaaagaccag cgcgtggcgg catctaaagt gctgactggc ccgcaggcta
    16861 aactggctgg cgataaagca gagttcgttg agaaagtgcg tcgcgcactg tacctgggta
    16921 aaatcgtctc ttacgcgcag ggcttctctc agctgcgtgc cgcgtctgac gagtataact
    16981 gggatctgaa ctacggcgaa atcgcgaaga tcttccgcgc gggctgcatc attcgtgcac
    17041 agttcctgca gaaaatcacc gacgcctacg ctgaaaatgc gggcattgcc aacctgctgc
    17101 tggcgccgta cttcaaaaat atcgctgacg aataccagca ggcgctgcgt gacgtcgtgg
    17161 cctatgctgt gcagaacggt attccggtac cgaccttctc tgcagcagtc gcgtactacg
    17221 acagctaccg cgctgcggta ctgccggcga acctgattca ggctcagcgt gactacttcg
    17281 gtgcgcatac ctataaacgc actgataaag aaggtgtgtt ccacaccgaa tggctggatt
    17341 aatctgaatt agttcatccg taaagccagg cccggagcgc atctccgggc ttttttattg
    17401 tctgaaaaca gcattcagtc aggtctgata ggcggcgaca cggtaattcg cgatatactg
    17461 gccgcaagcc gatccgacaa cgttgggtcc cacggtggtg atgcattcac cctcaaatgt
    17521 ttaaccggaa gaagttacag agcgaatgaa gataactatt tcaggaacag gttacgtcgg
    17581 cctgtcgaac ggcattctga tcgcccagca ccatgaagtg gtggccctgg atatcgttca
    17641 ggctaaggtc gacatgctga atcagaaaca gtcgccgatc gtcgataaag agatcgaaga
    17701 gtatctggcg accaaaccgc tgaatttccg tgcgaccact gataagcacg atgcttatcg
    17761 cgatgcagac tatgtgatca tcgccactcc gaccgattac gatcccaaaa ctaactattt
    17821 caatacctcc agcgttgagt ctgttatccg tgacgttgtt gaaatcaatc ccaatgcggt
    17881 gatggttatc aaatctacca ttccggtagg ctttaccaat tcgattaaag aaaaactggg
    17941 tatcgacaat attttcttct caccggaatt cctgcgtgaa ggccgtgcgc tgtacgacaa
    18001 cctgcatccg tcgcgtatcg ttatcggcga acgttccgag cgcgccgagc gttttgccgc
    18061 gctgctgcag gaaggggcag tgaagaagga tatcccgacg ctgttcaccg actcgaccga
    18121 agccgaagct attaagctat ttgcgaacac ttacctcgcg atgcgtgtgg cttatttcaa
    18181 cgagctggat agctatgcgg aaagcctggg cctgaattcc cgccagatta ttgaaggtgt
    18241 gtgcctggac ccgcgcatcg gtaatcacta taacaatcca tcttttggtt atggtggtta
    18301 ttgcctcccg aaagatacta aacaactgct ggcgaattat gcgtctgtgc cgaataacat
    18361 cgtcggtgcg attgttgacg ctaaccgtac ccgcaaagat tttatcgccg attctatcct
    18421 cgcccgcaaa ccaaaagtgg ttggggtata tcgccttgtc atgaagtcag gctccgacaa
    18481 tttccgcgca tcttcgattc aagggattat gaaacgaatc aaagcgaaag gcattccagt
    18541 gattgtgtat gaacctgcga tgaaagaaga tgaattcttt aattctcgcg tcgtacgcga
    18601 tctggatgca tttaagcaag aagcggatgt catcatttct aaccggatgg cggaagaatt
    18661 ggctgatgtg aaagagaagg tgtatacacg cgatctgttt ggtaatgatt gacaggttcg
    18721 tgcagcaata ataaagcccg gtgttatcgc cgggctttaa tctatccgtt acttatgtcg
    18781 ttcccgcaaa ttctcaatca ccgccgtcaa atccagctcc tgatcctgca acagcaccag
    18841 caggtgatac atcaaatccg acgcctcatt cttcagctca aacttatcgt gcaccgtggc
    18901 cgccagcgca gtttccacgc cttcttcacc cactttctgc gcgatacgct tggtgccgct
    18961 ggcgtacagc ttagcggtgt acgagcttgc cgggtcggcg tttttacgct cggcaagcag
    19021 ttgctcaagc tgatacagga acagccattg gtggctggtg tcgccaaagc agcttgaggt
    19081 gcctttatgg caagtcgggc caatcgggtt aaccagcacc agcagagtgt cgttgtcgca
    19141 gtcgggcgca atgcttacca cattcaggaa gtggccggag gtttcaccct tggtccacag
    19201 gcgctgtttg gtgcgcgaga aaaaggtcac tttgcccgtt tcctgcgttt tggtcagcgc
    19261 ttcctcattc atatacccca gcatcagcac ttcgccggat accgcgtgtt gaataatggc
    19321 gggcatcagt ccgtcggttt tttgccagtc cagttgttca gttaacatac ccgaatctcc
    19381 acgccctgcg ttgccaggta cgcttttagt tcaccaatat taataatctg tttgtggaat
    19441 accgaggccg ccagcgcgcc gtcgacgtcg gcgtcacgga aggcttcgag gaaatgttcc
    19501 atggtccccg caccaccaga ggcgatcagc ggtacgcggc aaacctcgcg cacttttttc
    19561 aactgctcca ggtcgtagcc gttacgcacg ccgtcctggt tcatcatatt gaggacgatc
    19621 tcgcccgcgc cgcgtttctg cacttcctgt acccagtcca gcgtttccca ttgggtcact
    19681 cgggtgcggc tttcatcgcc ggtgtattga ttgacgtgat atttgccggt gtcagcgtca
    19741 taccaggtat caatacccac tacgatgcac tgcacgccga agcggtccgc caggcgggtg
    19801 atcagctccg ggtccgccag tgccggg
//
