LOCUS       MN172357               18797 bp    DNA     linear   BCT 24-AUG-2019
DEFINITION  Escherichia coli strain 17-05676 O-antigen biosynthesis gene
            cluster, complete sequence.
ACCESSION   MN172357
VERSION     MN172357.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18797)
  AUTHORS   Lang,C., Hiller,M., Konrad,R., Fruth,A. and Flieger,A.
  TITLE     Whole genome-based public health surveillance of less common STEC
            serovars and untypable strains identifies four novel O genotypes
  JOURNAL   J. Clin. Microbiol. (2019) In press
   PUBMED   31366691
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 18797)
  AUTHORS   Lang,C., Hiller,M., Konrad,R., Fruth,A. and Flieger,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUL-2019) Division of Enteropathogenic Bacteria and
            Legionella (FG11), Robert Koch Institute, Burgstrasse 37,
            Wernigerode, Saxony-Anhalt 38855, Germany
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: A5 v. 2.1.3
            Assembly Name         :: OgN-RKI
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..18797
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="17-05676"
                     /isolation_source="food"
                     /db_xref="taxon:562"
                     /country="Germany"
     misc_feature    1..18797
                     /note="O-antigen biosynthesis gene cluster"
     gene            62..967
                     /gene="galF"
     CDS             62..967
                     /gene="galF"
                     /codon_start=1
                     /transl_table=11
                     /product="GalF"
                     /protein_id="QEE84037.1"
                     /translation="MDEIMTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVT
                     IMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGR
                     YVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQA
                     FVKYGLRNLKEGAKFRKGIEKLLSE"
     CDS             1340..2413
                     /codon_start=1
                     /transl_table=11
                     /gene="rmlB"
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="QEE84038.1"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLA
                     DVSDSERYVFEHADICDAAAMARIFALHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSALDSDKKNSFRFHHISTDEVYGDLPHPDEVNNTEELPLFTETTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KALPIYGKGDQIRDWLYVEDHARALYTVVTEGKAGETYNIGGHNEKKNLDVVHTVCDL
                     LDEIVPKEGSYRDQISYVADRPGHDRRYAIDSEKISRELGWKPQETFESGIRKTIDWY
                     LNNTEWCRRVQDGSYQRERLGLQ"
     CDS             2414..3289
                     /codon_start=1
                     /transl_table=11
                     /gene="rmlA"
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="QEE84039.1"
                     /translation="MKGIILAGGSGTRLYPITMGISKQLLPVYDKPMIYYPLSVLMLA
                     GIQDILVITTPEDQHGFIRLLGDGTQFGINLTYAIQPNPDGLAQAFIIGEKFIGQDSV
                     CLVLGDNIFFGQGFTPKLQAAAQRKKGATVFGYQVMDPERFGVVAFDNNFRAVSIEEK
                     PKIPKSNWAVTGLYFYDNDVIDHAKNTKPSSRGELEITSVNEAYLRNNLLTVELLGRG
                     FAWLDTGTHDSLIEAGSFVETVQKRQGMMVACPEEIAWRNGWLSKKDVLTLGEHLAKN
                     SYGQYLIDLVTKNEN"
     CDS             3279..3674
                     /codon_start=1
                     /transl_table=11
                     /gene="fdtA"
                     /product="WxcM-like domain-containing protein"
                     /protein_id="QEE84040.1"
                     /translation="MKIEFISFQKHGDERGILVALEENRNVPFEIKRVYYMFGTKENV
                     RRGYHAHKELRQLAITVSGSCKFLLDDGESKENVELSDPTRGLLIEPGIWHEMYDYSK
                     DCILMVLASDVYDESDYIRSYESFQEWSK"
     CDS             3671..4132
                     /codon_start=1
                     /transl_table=11
                     /gene="fdtC"
                     /product="N-acetyltransferase"
                     /protein_id="QEE84041.1"
                     /translation="MNKHKLSDVQSSNIGKGTRIWQFSVIFPGAIIGDDCNICAHTLI
                     ENDVVIGDRVTIKSGVYIWDGITLEDDVFIGPCVAFSNDKMPRSKKYPEKFARTVVKK
                     GASIGANATILPGLTIGMNSMVGAGAVVTKDVPDNVIVIGNPAIILKKMEY"
     CDS             4134..5237
                     /codon_start=1
                     /transl_table=11
                     /gene="fdtB"
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="QEE84042.1"
                     /translation="MISFLNLKKINGRYKKELIAACAKVIDSGWYIQGNELATFESEF
                     ASYCGTKYAVGVANGLDALTLVLRAWKIMGRLKDNDKIMVPANTYIASIISITQNNLV
                     PILVEPDSQTFNLTYDSLNKSWVDGIKAILPVHLYGQISPMQEIIEFARERNLLVLED
                     CAQAHGASIGGKKAGSWGDASGFSFYPGKNLGALGDAGIITSNDTELITTLRALRNYG
                     SHKKYENIYIGYNSRLDEIQAAMLSVKLKYIDKETERRREISKKYRCGIVNELITLPV
                     VLNEEGHVWHLFVIRCKEREKLVEYLDSHGIQTLVHYPIPPHKQIAYKDWNNLKFPIT
                     EDIHNTVLSIPLDPTMSDNEVEQVIKIINGFGK"
     gene            5234..6499
                     /gene="wzx"
     CDS             5234..6499
                     /gene="wzx"
                     /note="flippase"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="QEE84043.1"
                     /translation="MRKLLSVTTFTGMLTLLRMAAGFLMAKVIAVYLGPSGMAMLGQV
                     QNIVAILNGIISAPISPALIRYTAQYYDGGYRQCIPWWRASLGWVLIFMLILMPLMIL
                     FSHDLSLWLFSSKQYSYLVLAIVLCLPFSVLGIIINAVNNGVQNYKKYIGLGMLSVIA
                     STAIMIFLVIYGSVKGALLAISIQSGIIGVVLFICSVKEPWLKISYWVGAIDRDKFLY
                     IFRYILMALISALVFPLALLIIRNTLIDLEGWNVTGQWQAVWKISDAYLSVMTLALST
                     YYLPLLSKLDNLHDLRREIKSISKVIIPITILLSSVIYFSSGLIVRVLFTEEFKDAES
                     LFLIQLIGDNVKIIAWLYAYPLIAYGIAKWYIIAEISFALLFIFLGRLLISNYGVSGA
                     NWAYLLSYVIYFCFVFIVMNKVVIFSRKG"
     CDS             6504..7745
                     /codon_start=1
                     /transl_table=11
                     /gene="orf8"
                     /product="glycosyltransferase"
                     /protein_id="QEE84044.1"
                     /translation="MSSLIAIYHPSYHQGGTEVLFSRLVDVLIKSGNSIAVIDYENGI
                     LNTNLKKEGVTYYNVNSNEWYLLLDTYTFLISARNIMRFLFICKDHEINDPKVMFWQL
                     HPSELYSGHFPYTARIKSLLGYHFLRYFLKLIPGVTPFRKTIEQLTRNNNLKIMDEAC
                     LRESSWVLDCEIMENYLPLLTGLKQRNTVRYYSNSDKNTVDADFNVAIISRLDEFKTA
                     GVIKSITDILAYDSRILIHVVGDGKDRGLIQEKFKNVSNVFFHGFIINSELDDFFISY
                     NIRLLFAMGTSALEGVSRGVPTVLLPCADKPLKDNYVYKFIHDQCGYSLGEYLQTPFC
                     SKEYYSMVDVFNKYFENINKIHIDTLLFFNTYYAEENVNTKIINSISNVPVFNLRHEY
                     VNSTSRFLVNFMNSIKNKSGI"
     CDS             7789..8823
                     /codon_start=1
                     /transl_table=11
                     /gene="orf9"
                     /product="hypothetical protein"
                     /protein_id="QEE84045.1"
                     /translation="MTGAEHLSFNACIISDLLQQKKTIKLYCSDSQYSCLPESIRRKV
                     EFKKIPVIHGKSRSFVLKFLVDIFNILRIFFGNNEKIVLLSVFPPTLFVTSILAAIFR
                     KKVKIFLHGELNGLRDNVNRKITSYSFWVYWYFKLSLYNYLENYIVGEHIRESIDNVI
                     FIDSKKLKYINHPLTPKCFVSKKDIIYASIGYANGASYDALFSIMSEINKSCCHIGMV
                     SEELYEKYKSSCIIFHAKPGAGLEYEQYLKLVSRVQYGVFLYNHDYSFTTSGAMLDAM
                     SNDVVIVSKNNCFASYLENIKYPTIILKNTEELISLLEHLPEYYEMIEQYDTHLAKEN
                     FSKNSSSWIV"
     gene            8827..9873
                     /gene="wzy"
     CDS             8827..9873
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="QEE84046.1"
                     /translation="MEFYYLILLFLVIVSIISAGFDKKTHFNYFLAFTICVFFITISS
                     MRWERGTDWVSYYEIYQAAKNSTVCSNIYCLGVEPGYYFLNWVFSPFASYSIFLMILA
                     VLIIPIKTFFFYKMSDFPFLALLLYFCIMLYDVFPVRQSLATSLCLLYFLIYKEHKKL
                     SIAILIAALSIHYTSIIFFVSLFICTREKILTIKNIILLILSYATLTLIIMSPPEILA
                     SRINDYILNQKVYSEDITMTRNILKSIDQILIISICIGMLSKTGFSRTILNLSIFGSI
                     IFILGTFLAPQLARFGLFFVPFQIISISSSLLLVQKHSKFITFLIIVIYATIKLHLII
                     LPFYDLFVPFKIHI"
     CDS             9870..10682
                     /codon_start=1
                     /transl_table=11
                     /gene="orf11"
                     /product="glycosyltransferase"
                     /protein_id="QEE84047.1"
                     /translation="MNMNQHNQLVSIVTPIYNSAKWVKHLIKVVQEQTYQSWEMIIID
                     DCSNDETFSVLSEIARCDKRIKVFRNESNLGPGKTRNKAIEIARGRFIAFLDADDEWC
                     TNKLEVQVSAMLENGYYMSYHDYRHMSSDGKMIGDIVHGPDRLDWRTHHIHRGVGCLT
                     IMFDRTKGNLPFFPSIDNIIAEDFLAWSNLLNTGHVGHRIPYDLARYRLSKNTRSSNK
                     LKAVRSVWYIYRHIELIPFSQSLFFWLQYCKNAFLLHRRAVPYINVEKYDNE"
     CDS             10657..12093
                     /codon_start=1
                     /transl_table=11
                     /gene="manC"
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="QEE84048.1"
                     /translation="MLRSMIMNSIQPIILCGGSGTRLWPLSRELYPKQFLSITSEQSM
                     LQNTISRLKGLPVNDPILICNEKHRFIAAEQLRASKIKSGGIILEPVGRNTAPAVALA
                     ALSNLQNGKDPLLLVLAADHVFNDEIKFRAAVNNAMYHAELGKLVTFGINPLNPETGY
                     GYIKRGSLIDDIRPAYNVSAFVEKPDRNTAQKYVSSQEYYWNSGMFLFRASQYIEELN
                     KYRPDILEVCTAAIKTAQIDLDFIRINHEVFLDCPSDSIDYAVMERTSDAVVVPLDAG
                     WSDVGSWSSVWDVVTKNAENNVINGDVISLDTSNSYLHTESCLLTTIGINDLIIVCTR
                     DAVLVANKNVSQDVKHIVEAIKNGGRHEHHIHRVVYRPWGKYDSIDAGERYQVKRITV
                     KPGEGLSVQMHHHRAEHWVVVAGTAKVTINDNIMLLAENESVYIPVGATHCLENPGKI
                     PLDLIEVRSGSYLDEDDVVRFADRYGRA"
     CDS             12519..13889
                     /codon_start=1
                     /transl_table=11
                     /gene="manB"
                     /product="phosphomannomutase CpsG"
                     /protein_id="QEE84049.1"
                     /translation="MTILTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKSIVLG
                     GDVRLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPM
                     DYNGMKLVREGARPISGDTGLRDVQCLAEENEFAVLDETKRGRYQRITTRDAYIDHLL
                     GYINLANLKPMKLVFNSGNGAAGPVVDAIEARFKALGAPVEFIKVHNTPDGNFPNGIP
                     NPLLPECRDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLE
                     KNPGAKIIHDPRLSWNTVDVVTAAGGTPVMSKTGHAFIKERMRKEDAIYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVAELVCLKGKTLGELVRDRMAAFPASGEINSKLAQPVEAINR
                     VEQHFSREALAVDRTDGISMTFADWRFNLRSSNTEPVVRLNVESRGDVPLMEEKTKLI
                     LELLNK"
     gene            14053..15459
                     /gene="gnd"
     CDS             14053..15459
                     /gene="gnd"
                     /codon_start=1
                     /transl_table=11
                     /product="Gnd"
                     /protein_id="QEE84050.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWALNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            15708..16874
                     /gene="ugd"
     CDS             15708..16874
                     /gene="ugd"
                     /codon_start=1
                     /transl_table=11
                     /product="Ugd"
                     /protein_id="QEE84051.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDEIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELRDVADKVYTRDLFGSD"
     gene            16984..17997
                     /gene="wzz"
     CDS             16984..17997
                     /gene="wzz"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz"
                     /protein_id="QEE84052.1"
                     /translation="MRTWKFPSVRVMMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKM
                     TIIISVIVAIVLAIGYLAVAKEKWTSTAIITQPDVGQIAGYNNAMNVIYGQAAPKVSD
                     LQETLIGRFSSAFSALAETLDNQEEPEKLTIEPSVKNQQLPLTVSYVGQTAEGAQMKL
                     AQYIQQVDEKVNQELEKDLKDNIALGRKNLQDSLRTQEVVAQEQKDLRIRQIQEALQY
                     ANQAQVTKPQIQQTQDVTQDTMFLLGSEALESMIKHEATRPLVFSSNYYQTRQNLLDI
                     DNLDVDKLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALRNY
                     NAK"
     gene            complement(18093..18704)
                     /gene="hisI"
     CDS             complement(18093..18704)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="HisI"
                     /protein_id="QEE84053.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TIESGKVTFFSRTKQRMWTKGETSGNFLNVVSIAPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQGLDLTTVIENLRKRHQ"
BASE COUNT     5456 a   3484 c   4196 g   5661 t
ORIGIN
        1 cagggtaatt gatgctggcg aaaaaaatcg aacaagctat aattcagcaa ccattttaca
       61 ggtggatgaa ataatgacga atttaaaagc agttattcct gtagcgggtc ttgggatgca
      121 tatgttgcct gccactaagg cgattcccaa agagatgcta ccgatcgtcg acaagccaat
      181 gattcagtac attgttgacg agattgtggc tgcagggatc aaagaaatcc tcctggtgac
      241 tcatgcgtcc aagaacgcgg tcgaaaacca cttcgacacc tcttatgaat tagaatctct
      301 ccttgaacag cgcgtgaagc gtcaattgct ggcggaagtg caatctatct gcccgccggg
      361 cgtgactatt atgaacgtgc gtcagggcga acctttaggt ttaggccact ccattttgtg
      421 tgcgcgacct gccattggtg acaacccatt tgtcgtggta ctgccagacg ttgtgatcga
      481 cgatgccagc gccgacccgc tgcgttacaa ccttgctgcc atgattgcgc gcttcaacga
      541 aacgggccgc agccaggtgc tggcaaaacg tatgccgggc gatctctctg aatactccgt
      601 cattcaaacc aaagaaccgc tggatcgtga aggcaaagtc agccgcattg ttgaattcat
      661 cgaaaaaccg gatcagccgc agacgctgga ctcagacatc atggccgtgg gtcgctatgt
      721 gctttctgcc gatatttggc cggaactaga acgcactcaa ccaggtgcat ggggacgtat
      781 tcagctgact gatgccattg ccgaactggc gaaaaaacag tccgttgatg caatgctgat
      841 gactggtgac agttacgact gtggtaaaaa aatgggttat atgcaggcgt ttgtgaagta
      901 tggactacgc aacctgaaag aaggggcgaa gttccgtaaa ggcattgaga agctgttaag
      961 cgaataatga aaatctgacc gaatgtaacg gttgataaga aaattataac ggcagtgaag
     1021 attcgtggcg aaagtaattt gttgcgaata ttcctgccgt tgtcttatat aaacaatcag
     1081 aataacaacg agttagcaat aggattttag tcaaagtttt ccaggatttt ccttgtttcc
     1141 agagcggatt ggtaagacaa ttagcgtttg aatttttcgg gtttagcgcg agtgggtaac
     1201 gctcgtcaca tcgtaggaat gcatgcagtg ctctggtagc tgtaaagcca ggggcggtag
     1261 cgtgcattaa tacctctatt aatcaaactg agagccgctt atttcacagc atgctctgaa
     1321 gtaatatgga ataaattaag tgaaaatact tgttactggt ggagcaggat ttattggttc
     1381 tgctgtagtt cgtcacatta taaataatac gcaggatagt gttgttaatg tcgataaatt
     1441 aacgtacgcc ggaaacctgg aatcacttgc tgatgtttct gattctgaac gctatgtttt
     1501 tgaacatgcg gatatttgcg atgcagctgc aatggcgcgg atttttgctc tgcatcagcc
     1561 ggatgcagtg atgcacctgg ctgctgaaag ccatgttgac cgttcaatta ccggccctgc
     1621 ggcatttatt gaaaccaata ttgttggtac atatgtcctt ttggaagccg ctcgcaatta
     1681 ctggtctgct cttgatagcg acaagaaaaa tagcttccgt tttcatcata tttctactga
     1741 cgaagtctat ggtgatttgc ctcatcctga cgaagtaaat aatacagaag aattaccctt
     1801 atttactgag acgacagctt acgcgccaag cagtccttat tccgcatcca aagcatctag
     1861 cgatcattta gtccgcgcgt ggaaacgtac ctatggttta ccgaccattg taactaattg
     1921 ctctaacaat tatggtcctt atcatttccc ggaaaaattg attccattgg ttattctcaa
     1981 tgctctggaa ggtaaagcat tacctattta tggtaaaggg gatcaaattc gcgattggtt
     2041 gtatgtagag gatcatgctc gagcgttata taccgtcgta accgaaggta aagcaggtga
     2101 aacttataac attggtggac acaacgaaaa gaagaatctc gacgtggtac atacggtttg
     2161 cgacctgctg gatgaaatcg taccgaagga aggttcatac cgcgatcaga ttagctatgt
     2221 tgcggatcgt cctgggcatg accgtcgcta cgcgattgat tctgagaaaa ttagccgtga
     2281 acttggctgg aagccgcagg aaaccttcga gagcgggatc cggaaaacaa ttgattggta
     2341 tttaaataat acagagtggt gtcgtcgtgt acaagacggt agctatcaac gtgagcgttt
     2401 aggattacaa taaatgaaag gtattatttt agctggtggt tccggaacta ggctttatcc
     2461 catcacaatg ggtatttcca agcaattgct ccctgtctat gataaaccga tgatttacta
     2521 tcctttatca gttctgatgc tcgctgggat tcaagatatt ctggttatta ctacgccaga
     2581 agaccagcat ggatttatta gactactagg ggatggaacc caatttggta ttaatctcac
     2641 atatgcgata cagccaaatc ctgatggctt agctcaggct tttattatag gtgaaaaatt
     2701 tatcggtcaa gactctgtat gtttagttct tggggataat atattttttg ggcagggatt
     2761 tacccccaaa cttcaagcag cagctcagag aaaaaaaggt gctacagttt ttggatatca
     2821 agtaatggat cctgagcgat ttggtgtcgt tgcatttgat aataatttca gagcagtaag
     2881 cattgaggaa aaacctaaaa ttccgaagtc aaattgggca gtaaccggtc tttattttta
     2941 cgataatgat gttatcgacc atgcaaaaaa tactaaaccc tcatctcgtg gtgaattaga
     3001 gatcacatcg gtgaatgaag cttatctaag aaataattta ttgacagtag agttattagg
     3061 gcgcggtttt gcgtggcttg ataccggaac tcatgatagc ttaattgaag ccggtagttt
     3121 tgtagaaacg gttcagaagc ggcaaggcat gatggttgcg tgtcctgagg aaattgcatg
     3181 gcgaaatggt tggttgagta aaaaagatgt tctgacatta ggagaacatt tagccaaaaa
     3241 ctcttatgga caatatttaa tcgatttagt gactaagaat gaaaattgaa tttatatcat
     3301 ttcaaaagca tggcgatgaa cgcggcatat tagttgcact ggaagaaaat agaaatgttc
     3361 cttttgaaat aaaaagagtc tactacatgt tcggtacaaa agagaatgta cgtagaggat
     3421 atcatgcaca taaggaatta cgacaacttg ctattacggt aagtggatca tgtaaatttt
     3481 tgttggatga tggtgaaagt aaggaaaatg ttgagttgag cgatcctaca agaggtttac
     3541 ttattgaacc gggaatttgg catgaaatgt atgattattc aaaagattgc attcttatgg
     3601 tattagctag tgatgtatat gatgagagtg actatattag aagttacgaa tcctttcagg
     3661 aatggagtaa atgaataaac ataaattaag tgatgttcag tcctcgaata taggaaaggg
     3721 tactaggatt tggcaattct ctgtgatatt ccccggggcg attataggag atgattgcaa
     3781 tatttgtgca catacactta tcgaaaatga tgtcgtcata ggagatagag ttacaataaa
     3841 gtctggtgta tatatatggg atgggattac cttagaggat gacgttttta ttggaccatg
     3901 tgtggctttt agtaatgata aaatgccgag gtcaaaaaaa tatcccgaga aattcgctcg
     3961 aacagtagtc aaaaagggtg cgtctattgg agcaaatgca acgattttgc ccggcttaac
     4021 aataggaatg aatagtatgg ttggggctgg tgctgtggtt acaaaagatg taccggataa
     4081 cgttatagta attggcaatc cggcaataat ccttaagaaa atggaatatt aatatgatta
     4141 gctttctgaa tttgaagaaa attaatggaa gatataaaaa agagttaata gcagcctgtg
     4201 ctaaggtcat tgattcaggc tggtatatac aaggaaacga attagccacg ttcgaatctg
     4261 aatttgctag ttattgcggt acaaagtatg ccgtaggagt tgctaatggt ttagatgctc
     4321 taacattggt acttagggct tggaagataa tggggaggtt gaaagataat gataaaataa
     4381 tggtgcccgc caatacgtat atagcttcga ttatttcaat tacgcagaat aacttagttc
     4441 ctatattagt tgagccagac tctcaaactt ttaatcttac ctatgacagc ttgaataaat
     4501 cttgggtgga tggcataaaa gctatccttc ctgtacattt gtatgggcaa atatcaccaa
     4561 tgcaagaaat tatcgaattt gcccgtgaaa gaaatttgtt agtattagaa gactgtgctc
     4621 aggcgcatgg tgcttcaatt ggagggaaga aagctggttc atggggggat gcttcaggtt
     4681 tcagctttta tccaggcaaa aatcttgggg ctctgggaga tgctgggatt ataacatcca
     4741 atgatactga actgataaca accctaagag cattacgaaa ttatggatca cataaaaaat
     4801 atgaaaatat atatataggg tataatagtc gtcttgatga aattcaagcg gcaatgttat
     4861 ccgtcaagct taagtatatt gataaagaga ctgaaagacg tagggagata tcaaaaaaat
     4921 accgttgtgg gattgtaaat gaattaatta ctctacctgt tgtattaaat gaagaaggac
     4981 atgtatggca tctttttgtt attcgttgta aagaaagaga gaaacttgtt gaatatcttg
     5041 attctcatgg gatccaaacc ttggttcatt atccaattcc accacataaa caaattgcct
     5101 ataaagattg gaataattta aaatttccaa tcacagagga tattcataat acagttctat
     5161 caataccatt agatccaaca atgtcagata atgaagtcga gcaagttata aagattataa
     5221 acggctttgg taaatgagaa aattactatc tgtaacaacg ttcactggta tgttgaccct
     5281 gctgcgaatg gcagcagggt ttttaatggc gaaagttatc gctgtttatt taggaccatc
     5341 tggtatggca atgctcggtc aagtccaaaa tattgtagcc attcttaatg gtatcataag
     5401 tgctcctatt tctcctgcgt tgatacgcta tacagcacag tattatgatg gaggctatag
     5461 acaatgtata ccatggtgga gagcgagtct aggatgggtg ttaatattca tgctgatatt
     5521 aatgccatta atgattcttt tttcacatga tttatcattg tggttattta gctctaaaca
     5581 atatagctac ttagtattgg ctattgtgct ctgcctccca ttttcagttt tgggcattat
     5641 aattaacgct gtcaataatg gtgtccaaaa ttataagaaa tacattgggc ttggaatgct
     5701 ctcggttatt gcatctacag caataatgat attccttgta atatatggaa gtgtaaaagg
     5761 ggctttactg gctatttcta ttcaaagtgg aattattggt gttgttcttt ttatatgttc
     5821 agttaaagaa ccgtggctaa agatttcata ttgggttggg gcaatagata gagataaatt
     5881 tttatacatt ttccgttata ttttgatggc attgatcagc gcattagttt ttccacttgc
     5941 cttgcttatt atacgaaata cgcttataga tttagaaggg tggaatgtaa cagggcaatg
     6001 gcaggctgtt tggaaaatat cagatgctta tctttcagtt atgacgttag cattatcaac
     6061 atattatttg ccattattat caaaactaga taatctccat gatttaagga gggaaattaa
     6121 aagcatttct aaagtaatta tccctataac aattttatta tcatcagtta tatattttag
     6181 tagtggttta attgttaggg ttttatttac ggaggaattt aaagatgccg aatcattatt
     6241 cctgattcaa cttattggcg ataatgtaaa aattatagca tggctttatg cttatccatt
     6301 gatcgcatat ggtattgcta aatggtacat cattgccgaa atttctttcg ctcttttatt
     6361 cattttttta ggccgtctac ttatatcaaa ttatggcgtc agtggtgcga attgggcata
     6421 tcttctgtca tatgttattt atttttgttt tgtttttatt gtcatgaaca aagttgtgat
     6481 tttctctcgg aagggataaa tgaatgagtt cattaattgc tatttatcac cctagttatc
     6541 atcaaggcgg aacagaagtt cttttttcac gcttagtgga tgttctaatt aaatcaggga
     6601 actcaatagc ggtgattgat tatgaaaatg gtattcttaa taccaatcta aaaaaagaag
     6661 gagtaacata ttataatgtc aatagcaatg agtggtatct gttgcttgat acgtatacct
     6721 tcttgataag cgcaagaaat ataatgcgct ttttgtttat ttgtaaggat catgagataa
     6781 atgatcctaa agttatgttt tggcaattac atccatctga attatattct ggtcattttc
     6841 cttatactgc acgaattaaa tctttacttg gttatcattt cttgagatac tttttgaaat
     6901 taattccagg agtaactccc tttcgcaaaa caattgagca gctaacaaga aataataatc
     6961 ttaaaataat ggatgaagca tgtttaagag aatcctcttg ggtcctagac tgtgaaatta
     7021 tggaaaacta tcttccattg ctgactggat tgaagcaaag aaatactgtt cgctattact
     7081 ctaatagtga caagaataca gttgatgctg attttaatgt ggcaattatt agtcggttgg
     7141 acgaatttaa aaccgctggt gttataaaat caataacgga tattctcgca tatgactcta
     7201 ggatattaat ccatgtagtt ggagatggta aggatagggg attgatacag gagaaattta
     7261 aaaatgtgag caatgttttt tttcatggtt ttataattaa ttcagaattg gatgattttt
     7321 ttataagtta taatattaga ctattatttg caatggggac ttctgcactt gaaggtgttt
     7381 ctcgaggggt tcctactgtt ctattaccat gtgcagataa acctctaaaa gataactatg
     7441 tatataagtt tatacatgat caatgtggtt attccttagg ggagtatttg caaactcctt
     7501 tttgtagtaa ggaatattat tcgatggttg atgtttttaa taaatatttt gaaaatatca
     7561 ataaaatcca tattgacact ttgttgtttt ttaatacata ttatgcagaa gaaaatgtga
     7621 atacaaaaat tattaattct atcagcaatg tgcctgtgtt taatttgagg catgagtatg
     7681 tgaactcgac ttcgcgattc ttggttaatt tcatgaatag catcaaaaat aaatcgggaa
     7741 tttaataaag tgggaaatga taaaaaaatt gtaatcgctg agactaatat gacaggagca
     7801 gagcatctaa gcttcaacgc ttgtattata tctgatttac tacagcaaaa aaaaactatt
     7861 aaactttact gctctgattc tcaatatagt tgtttgccgg aaagcataag gagaaaggta
     7921 gaatttaaaa aaataccggt aatacatggg aaatctcgaa gttttgtcct taagtttctt
     7981 gttgatattt ttaatatttt aaggatattt ttcggtaata atgaaaaaat agttttgctt
     8041 tcagtatttc ctccaacgct tttcgtaact agtattcttg cggctatctt cagaaaaaaa
     8101 gtaaagattt ttttgcatgg tgaattaaac gggctaagag ataatgttaa tcgtaaaata
     8161 acatcatatt ctttttgggt gtattggtat tttaaactta gtttatacaa ttatcttgaa
     8221 aattatatcg taggtgagca tattagagaa agtatagata atgtcatatt tattgattca
     8281 aaaaaactga agtatataaa tcatccatta acgcctaaat gctttgtttc aaaaaaagat
     8341 atcatttacg catctattgg atatgcaaat ggggcttcat atgacgcctt gtttagtata
     8401 atgtctgaga ttaataagtc atgttgtcat attggtatgg ttagtgagga gttatatgaa
     8461 aaatataaat cctcatgcat tatatttcat gcaaaaccgg gggcggggtt ggaatatgag
     8521 caatatttaa agctggtttc tagagttcaa tatggggtgt ttttatataa tcacgattat
     8581 agctttacaa caagcggggc tatgcttgat gcaatgagta acgatgtagt tattgtttca
     8641 aagaataatt gttttgcatc ctatttagaa aatattaagt acccaactat tattttaaaa
     8701 aataccgagg agttaatttc cctattagag catctgcccg aatactatga gatgattgag
     8761 caatatgata cgcatctggc aaaagaaaat ttctcaaaaa actcatcctc atggatagta
     8821 tagcatatgg aattttatta tttaattttg ttattcttag taattgtaag tataatatca
     8881 gcaggatttg ataaaaaaac acactttaac tatttcttgg cttttacaat atgtgttttt
     8941 tttatcacta tttcttcaat gagatgggaa cgaggcactg attgggtctc ttattacgaa
     9001 atataccaag cagcaaaaaa tagtaccgta tgttctaata tatactgttt aggggtggaa
     9061 ccagggtatt attttttaaa ctgggtgttc tctccatttg catcatactc tattttttta
     9121 atgatcttag ccgttttgat tattccaatt aaaacgtttt ttttctataa gatgtcagat
     9181 tttccttttt tagccttatt attgtatttt tgcatcatgc tttatgatgt tttccctgtt
     9241 cggcaaagtt tggcaacttc attgtgttta ttatattttt tgatttataa ggaacataaa
     9301 aaattatcta tagccatatt gatagcagca ttatctattc actatacatc aataattttt
     9361 tttgttagcc tttttatatg cacaagagaa aagattctta ctataaaaaa tattatttta
     9421 ttaattttat catatgcgac attaacccta ataataatga gccctcccga aattcttgcg
     9481 agcaggataa atgattatat tttaaaccaa aaagtttact cagaagatat tactatgacc
     9541 cgtaatatac taaagtcgat tgatcaaatt ttaataatct ctatatgtat tggaatgctt
     9601 agtaaaacgg gttttagtag gacgattctt aatttgtcga tatttggctc gattattttt
     9661 atattaggta ctttccttgc tccacagtta gctcgttttg gtcttttttt tgtgccattc
     9721 cagattatct caatatcgtc ctcactatta cttgtacaaa aacactcaaa atttattacg
     9781 tttttaatta tcgttattta tgcaactatt aaattacatt taattatact tcctttttat
     9841 gatttatttg ttccgttcaa aatacacata tgaatatgaa tcagcataac caattggttt
     9901 cgattgtaac tccgatatat aactctgcta agtgggttaa gcatttaatt aaagtagttc
     9961 aagaacaaac ttatcagtca tgggagatga ttattattga tgactgttca aatgatgaaa
    10021 catttagtgt tcttagtgaa atagctagat gtgataaaag gattaaagta tttagaaatg
    10081 aatcaaattt gggcccagga aaaacaagaa acaaagctat tgaaattgct cgtgggcgtt
    10141 ttattgcttt ccttgatgca gatgatgagt ggtgcactaa taagttagaa gtgcaagtat
    10201 cagctatgtt agaaaatggt tattatatgt cttaccacga ttacaggcac atgagtagtg
    10261 atgggaaaat gatcggggat attgttcatg ggcctgacag gctggattgg cggacccatc
    10321 acattcacag gggagtaggc tgtttaacaa taatgttcga tagaacaaaa gggaatttac
    10381 catttttccc tagcatcgat aatataattg ctgaggattt tttggcatgg agtaacttgt
    10441 taaacactgg tcatgttgga catagaattc cttacgacct tgctcgatat agattatcaa
    10501 aaaatacaag gtcatctaat aaacttaagg cagtcaggtc tgtttggtat atttatagac
    10561 atattgaatt aattcctttt tcacagtctt tatttttttg gcttcagtat tgtaagaacg
    10621 cttttctatt acatagacga gcagtaccat atattaatgt tgagaagtat gataatgaat
    10681 agcattcaac caatcattct ctgtggtggg agtggtacaa gattgtggcc tctctctaga
    10741 gagttatatc ctaaacaatt tttgagcata acttctgaac aatcaatgct gcaaaataca
    10801 atatcccgct taaaaggatt gcctgtaaat gatccaattt taatttgtaa tgaaaagcac
    10861 agatttattg cggcagagca gttacgtgct tctaaaatta aatcgggggg tattattctt
    10921 gaaccagtag gaagaaatac agccccagca gttgcacttg ctgcattgtc taatcttcag
    10981 aatggaaaag atcccttact tttagtactg gcagctgatc atgtttttaa tgatgaaatt
    11041 aagttccggg cggcagtaaa taatgccatg tatcatgctg aacttggcaa gttagttaca
    11101 tttggcatta atcctttaaa tcctgaaact ggctatgggt atattaaacg tgggtcttta
    11161 atcgatgata ttcgtcctgc ttataatgta tctgctttcg ttgaaaaacc tgatagaaac
    11221 acagcccaaa aatatgtatc gagccaagag tattattgga atagtggcat gttcctattt
    11281 agagctagcc aatatattga agaattaaat aaatatcgac ccgatattct agaagtatgt
    11341 actgctgcga ttaaaacagc tcagattgat ttggatttta tccgtattaa tcatgaagta
    11401 tttttagact gcccatccga ttccattgac tatgcggtaa tggaaagaac atctgatgcg
    11461 gttgttgttc ctctggatgc aggatggagt gatgtaggct cttggtcctc tgtttgggat
    11521 gttgttacta aaaatgctga aaataatgta atcaatggtg atgtaattag cttagataca
    11581 tctaatagct atttacatac tgaaagctgt ctccttacaa cgataggtat aaatgatctc
    11641 atcattgtgt gtacgcgaga tgctgttttg gttgctaata aaaatgtcag tcaggatgta
    11701 aaacatattg ttgaggctat taaaaacggt ggccgccatg aacaccatat tcatcgcgta
    11761 gtttatcggc catggggcaa gtatgactct attgatgccg gagagcgtta tcaggtgaag
    11821 cgaattaccg ttaagcctgg cgagggattg tccgtgcaga tgcatcatca tcgggctgag
    11881 cactgggttg ttgtggctgg taccgcgaag gtgacaatca atgacaatat catgctgctt
    11941 gctgaaaacg agtctgtcta tattccagtg ggggcgaccc attgtcttga aaaccccggg
    12001 aaaatcccgc tcgatctgat tgaagtgcgc tctggatctt accttgatga ggatgatgtg
    12061 gtgcggtttg cggacagata cggccgcgct taacacaaca tcatcgttgc cggatggcgg
    12121 cctgtacgcc ttatccggct ttgtattatc cctcctgtgc agagaaaatc ggccagtttt
    12181 ctctgaccag cagtccgcat gccgtatccc gccttgggtt tctagcctgt gctgtagttt
    12241 tatatagcgg actgactttc tccaaaagtg ataaaccgga cagtatcatg gacgggtttt
    12301 tccagtaacc cgcttttgca aggtagattt cactatggaa catgagcttc attataatgg
    12361 tatcgacacc gctaaagaga aactggatgt cgatgtactg tgtactgatg gccgtcatcg
    12421 caccatataa ttcgctatac aaacgagcgg ttagtcattt gttgaaaaat tatctccatt
    12481 cagaaaatgg ctaattgtta cctgaagaag ggtaaattat gacgatatta acctgtttca
    12541 aagcctacga tattcgtggc aaacttggtg aagaattaaa cgaagatatc gcatggcgta
    12601 ttggccgcgc ttatggcgaa ttcctgaagc caaaatctat tgtcctgggc ggcgatgtgc
    12661 gcctgaccag cgagacgtta aagctggcgc tggcgaaagg actgcaggat gcgggggtgg
    12721 atgtgctgga tattggcatg tcgggcactg aagagattta cttcgctacc ttccatctcg
    12781 gcgtggatgg cggcatcgaa gttaccgcca gccataaccc gatggattac aacggcatga
    12841 aactggtgcg cgaaggggcg cggcccatca gcggtgatac tggtctgcgt gacgtgcagt
    12901 gcttggcgga agagaatgag ttcgcggttc tcgatgagac aaaacgtggc cgctaccagc
    12961 gaattactac ccgcgatgct tacattgatc acctgctggg ttacatcaat cttgccaacc
    13021 tgaaaccgat gaagttagtg ttcaactccg ggaacggcgc ggcgggtccg gtggtggacg
    13081 ccatcgaagc ccgctttaaa gccctcggcg caccggtgga attcatcaaa gtgcacaata
    13141 cgccggacgg caatttcccc aacggtattc ctaaccccct gctgccggaa tgccgcgacg
    13201 acacccgcaa tgcggtcatc aaacacggtg cggatatggg cattgccttt gatggcgatt
    13261 ttgaccgctg cttcctgttt gacgaaaaag ggcagtttat cgagggctac tacattgtcg
    13321 gtttgctggc agaagcgttc ctcgaaaaaa atcccggcgc gaagatcatc cacgatccac
    13381 gtctctcctg gaacaccgtt gatgtggtga ctgccgcagg cggcacgccg gtgatgtcga
    13441 aaaccggaca cgcctttatt aaagaacgga tgcgcaagga agacgccatc tacggtggcg
    13501 aaatgagcgc ccaccattac ttccgtgatt tcgcttactg cgacagcggc atgatcccgt
    13561 ggctgctggt ggccgaactg gtgtgtctga aaggaaaaac gctgggcgaa ctggtgcgcg
    13621 accggatggc agcgtttccg gcaagcggtg agatcaacag caaactggcg caacccgttg
    13681 aggcgattaa ccgcgtcgaa cagcacttta gccgcgaggc gctggcggtg gatcgtaccg
    13741 atggcatcag catgaccttt gccgactggc gctttaacct gcgctcctcc aacaccgaac
    13801 cggtggtgcg gttgaatgtg gaatctcgcg gtgatgtgcc gctgatggaa gaaaagacaa
    13861 agcttatcct tgagttactg aataagtaat tgagtaaatt catataaata ggttttaaaa
    13921 aacggaaaag atgagatatt cagtgtggta tagcaaaggt aatgctattc accatctcta
    13981 tgagtgagtt aacatctata ccacatttaa gccgcacact cggcggtgac caccccctga
    14041 caggagtaaa caatgtcaaa gcaacagatc ggcgtagtcg gtatggcagt gatggggcgc
    14101 aatcttgcgc ttaacatcga aagccgtggt tataccgtct ctattttcaa ccgttcccgt
    14161 gagaagacgg aagaggtgat tgccgaaaat ccaggcaaga aactggttcc ttactatacg
    14221 gtgaaagagt ttgttgaatc tctggaaacg cctcgtcgca tcctgttaat ggtgaaagca
    14281 ggtgctggca cggatgctgc tattgattcc ctcaagccgt acctcgataa aggtgacatc
    14341 attattgatg gtggtaatac cttcttccag gacaccattc gccgtaaccg tgagctttct
    14401 gccgaaggct ttaacttcat cggtaccggt gtttccggtg gtgaagaggg cgcgctgaaa
    14461 ggtccttcca ttatgcctgg tggccagaaa gaagcctatg aactggttgc tccgatcctg
    14521 accaaaatcg ccgcagtagc tgaagacggt gagccatgcg ttacctatat tggtgccgat
    14581 ggcgcaggtc actatgtgaa gatggttcac aacggtattg aatacggtga tatgcagctg
    14641 attgctgaag cctattctct gcttaaaggt ggcctgaatc tctctaacga agaactggca
    14701 cagaccttta ccgagtggaa taacggtgaa ctgagcagct acctgatcga catcaccaaa
    14761 gatatcttca ccaaaaaaga tgaagacggt aactacctgg ttgatgtgat tctggatgaa
    14821 gcagcaaaca aaggtaccgg taaatggacc agccagagcg cgctggatct cggcgaaccg
    14881 ctgtcgctga ttaccgagtc tgtgtttgca cgttatatct cgtctctgaa agatcagcgc
    14941 gttgccgcgt ctaaagttct ctctggcccg caagcacagc cagcaggcga caaggctgag
    15001 ttcatcgaaa aagttcgccg tgcgctgtat cttggcaaaa tcgtttctta cgctcagggc
    15061 ttctctcagc tgcgtgctgc gtctgaagaa tacaactggg ctctgaacta cggcgaaatc
    15121 gcgaagattt tccgtgctgg ctgcatcatc cgtgcgcagt tcctgcagaa aatcaccgat
    15181 gcttatgccg aaaatccgca gatcgctaac ctgctgctgg ctccgtactt caagcaaatt
    15241 gccgatgact accagcaggc gctgcgtgat gtcgtcgcat atgcagtaca gaacggtatc
    15301 ccggttccga ccttcgccgc tgcggttgcc tattacgata gctaccgtgc cgctgttctg
    15361 cctgcgaacc tgatccaggc acagcgtgac tatttcggtg cgcatactta taagcgcatt
    15421 gataaagaag gtgtgttcca tactgaatgg ctggattaat ctgatttaac caacaataaa
    15481 attgaggccc ggcgtatatt gcaccgggct tttttttgcc aattatctta tagactaaat
    15541 ttcactgctt aatattaact taataaatat cagctattct tataaagaaa atctgaattg
    15601 tttttcgttg cgttgaccat cgaacaacgt agcgttaaaa cttttagctc ttatcaggat
    15661 gctaaaaaca tcatgattca cagttaagtt aattctgaga gcatgaaatg aaaatcacca
    15721 tttccggtac tggctatgta ggcttgtcaa acgggcttct aatcgcacaa aatcatgagg
    15781 ttgtggcatt agatatttta ccgtcacgcg ttgctatgct gaatgatcgg atatctccta
    15841 ttgttgataa ggaaattcag cagtttttgc aatcagatga aatacacttt aatgccacat
    15901 tagataaaaa tgaagcctac cgggatgctg attatgtcat catcgccact ccaaccgact
    15961 atgatcctaa aactaattat ttcaatacat ccagtgtaga atcagtaatt aaagacgtag
    16021 ttgagataaa cccttatgcg gttatggtca tcaaatcaac ggttcccgtt ggttttaccg
    16081 cagcgatgca taagaaatat cgtactgaaa atattatatt ctccccggaa tttctccgtg
    16141 agggtaaagc cctttacgat aatctccatc cttcacgtat tgtcatcggt gagcgttcag
    16201 aacgcgcaga acgttttgct gcgctgttac aggaaggcgc gattaagcaa aatatcccga
    16261 ccctgtttac cgactccact gaagcagaag cgattaaact ttttgcaaac acctacctgg
    16321 cgatgcgcgt ggcgtacttt aacgaactgg atagctacgc agaaagttta ggtctgaata
    16381 ctcgccagat tatcgaaggc gtttgtctcg atccgcgtat tggcaaccat tacaacaacc
    16441 cgtcgtttgg ttatggtggt tattgcttgc cgaaagatac caagcagtta ctggcgaact
    16501 atcagtctgt gccgaataac ctgatctcgg caattgtcga tgcaaaccgc acgcgtaagg
    16561 attttattgc cgatgccatt ttgtcacgca aaccgcaagt ggtgggtatt tatcgtctga
    16621 ttatgaagag cggttcagat aacttccgtg cgtcttctat tcaggggatt atgaagcgta
    16681 tcaaggcgaa aggcgttgaa gtgatcatct acgagccagt gatgaaagaa gactcattct
    16741 tcaactctcg cctggaacgt gatctcgcca ccttcaaaca acaagccgac gtcattattt
    16801 ccaaccgtat ggcagaagag cttagggatg tggcagataa ggtctacacc cgcgatctct
    16861 ttggcagcga ctaacatctt gttatcaggg ctatttacgc cctgattgtc ttttgttact
    16921 tacgcaacaa ttcattattt ttatcactta tcctatagca ttcacgggga ttatcgctaa
    16981 actatgcgga cttggaaatt tccgtcagtt agggtaatga tgagagtaga aaataataat
    17041 gtttctgggc aaaaccatga cccggaacag attgatttga ttgatttact agtgcagttg
    17101 tggcgtggca agatgacaat catcatttcc gtcattgtag ctattgtcct ggctattggt
    17161 tatttggcag tagcgaagga gaaatggacg tcaacagcaa ttatcactca gcccgacgtg
    17221 gggcaaattg ctggctataa caatgccatg aatgttatat atggtcaggc tgcaccgaaa
    17281 gtatcggatt tgcaggagac gttaattggt cgcttcagtt ctgccttctc tgcattagca
    17341 gaaacgctgg ataatcagga agagccagag aaacttacca tcgaaccttc tgttaagaac
    17401 cagcaattac cattgactgt ttcttatgtt gggcaaacag cagagggcgc acaaatgaag
    17461 ttggcccaat acattcagca agttgatgaa aaagtgaatc aagagctaga aaaggatctc
    17521 aaagacaaca ttgctctggg acggaaaaac ttgcaggact ctttaagaac tcaggaagtg
    17581 gttgcgcagg agcagaaaga tctgcgtatc cgtcagattc aggaagcgtt gcagtatgcg
    17641 aatcaggcgc aggtgacaaa gccgcagatt cagcagacac aggacgtaac ccaagatact
    17701 atgttccttt tggggagcga agcgctggag tcgatgatta agcacgaggc gactcgtccg
    17761 ttggtgttct catcaaacta ctatcagact cgtcaaaacc tgctggatat cgacaatctt
    17821 gacgttgata aacttgatat tcatgcttac cgctatgtga tgaaaccgac gttacctatt
    17881 cgtcgcgata gcccgaaaaa ggcaattact ttgattctgg cggtgctgct gggcggcatg
    17941 gttggcgcgg ggattgtctt ggggcgtaac gctctacgta attacaacgc gaagtaatct
    18001 tttcggtttt aaagaaaatg ggcagggtgg tgacaccttg cccgtttttt tgccggatgc
    18061 gacaacaaca tcgcatccgc ttaccccgca actcactgat gccgtttacg caggttctca
    18121 attaccgtcg ttaagtccag cccctgatcc tgcaacaaca ccagcaggtg atacatcaag
    18181 tcagatgctt cgttggtcag ttcaaagcgg tcatgcaccg ttgctgccag tgcggtttcc
    18241 acgccttctt cgcccacttt ctgcgcaatg cgtttggtgc cgctggcata cagtttggca
    18301 gtgtaagagg tttccgggtc ggcagatttg cgttcggcga gcagttgttc cagttgatac
    18361 aggaacagcc actggtgagc ggtgtcgccg aagcagctgc tggtgccttt gtggcaggtc
    18421 gggccgatgg gattcgccag caccagtaac gtgtcgttgt cgcagtccgg cgcaatactc
    18481 accacattga ggaaattgcc agacgtttcg cctttggtcc acattcgctg tttagtgcgc
    18541 gagaagaagg tgactttgcc gctttcgatg gttttatcta aggcttccgg gttcatatag
    18601 cccagcatta acacttcgcc ggataccgcg tgttgcacaa tcaccggcat cagtccgtcg
    18661 gttttttccc agtccagttc gcgacgttgt tgttctgtta acatatcctg atctccacgc
    18721 cctgtgttgc caggtacgct tttaattcac caatattgat tatttgtttg tggaatacgg
    18781 aagctgccag cgcgccg
//
