LOCUS       LC177551               19834 bp    DNA     linear   BCT 15-DEC-2018
DEFINITION  Escherichia coli DNA, O-antigen biosynthesis gene cluster OgN14,
            strain: E167.
ACCESSION   LC177551
VERSION     LC177551.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., von Mentzer,A., Kikuchi,T. and Thomson,N.R.
  TITLE     An untypeable enterotoxigenic Escherichia coli represents one of
            the dominant types causing human disease
  JOURNAL   Microb Genom 3 (2017) In press
  REMARK    DOI:10.1099/mgen.0.000121
            Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 19834)
  AUTHORS   Iguchi,A., von Mentzer,A. and Thomson,N.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-AUG-2016) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuenkibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..19834
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="E167"
                     /db_xref="taxon:562"
                     /note="Escherichia coli O-antigen biosynthesis gene
                     cluster OgN14"
     gene            14..1408
                     /gene="wcaM"
     CDS             14..1408
                     /gene="wcaM"
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis protein"
                     /protein_id="BAV90491.1"
                     /translation="MPFKKLSRRTFLTASSALAFLHTPFARALPARQSVNINDYNPHD
                     WIASFKQAFGEGQTVVVPGGLVCDNINTGIFIPAGKTLHILGSLRGNGRGRFVLQDGS
                     QVTGEDGGSMHNITLDVRGSDCTIKGLAMSGFGPVTQIYIGGKNKRVMRNLTIDNLTI
                     SHANYAILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDSDILISDHIIERINCT
                     NGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGKHFVIRNIK
                     ARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGKYLSIPQNF
                     RVNNIQLDNTHLAYKLRGIQISAGNAVSFVSLTNIEMKRASLELHNKPQHLFMRNIKV
                     MQESSVGPALSMNFDMRKDVRGVFMAKEETLLSLANVHAVNERGQSSVDIDRINHHIV
                     NVEKINFRLPERRE"
     gene            1566..2561
                     /gene="gne"
     CDS             1566..2561
                     /gene="gnu"
                     /note="OgN14_1"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4-epimerase"
                     /protein_id="BAV90492.1"
                     /translation="MNDNVLLIGASGFVGTRLLETAIADFNIKNLDKQQSHFYPEITQ
                     IGDVRDQQALDQALAGFDTVVLLAAEHRDDVSPTSLYYDVNVQGTRNVLAAMEKNGVK
                     NIIFTSSVAVYGLNKHNPDENHPHDPFNHYGKSKWQAEEVLREWYNKAPTERSLTIIR
                     PTVIFGERNRGNVYNLLKQIAGGKFMMVGAGTNYKSMAYVGNIVEFIKYKLKNVAAGY
                     EVYNYVDKPDLNMNQLVAEVEQSLNKKIPSMHLPYPLGMLGGYCFDILSKITGKKYAV
                     SSVRVKKFCATTQFDATKVHSSGFVAPYTLSQGLDRTLQYEFVHAKKDDITFVSE"
     gene            2793..3686
                     /gene="galF"
     CDS             2793..3686
                     /gene="galF"
                     /note="OgN14_2"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAV90493.1"
                     /translation="MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNV
                     RQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRS
                     QVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLS
                     ADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFRKGIEKLLSE"
     gene            4058..5143
                     /gene="rmlB"
     CDS             4058..5143
                     /gene="rmlB"
                     /note="OgN14_3"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6 dehydratase"
                     /protein_id="BAV90494.1"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLA
                     DVSDSERYVFEHADICDAAAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSALDSDKKTSFRFHHISTDEVYGDLPHPDEVNNNEELPLFTETTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KALPIYGKGDQIRDWLYVEDHARALYTVVTEGKAGETYNIGGHNEKKNIDVVLTICDL
                     LDEIVPKEQSYREQITYVADRPGHDRRYAIDAEKISRELGWKPQETFESGIRKTVEWY
                     LSNTKWVDNVKSGAYQSWIEQNYEGRK"
     gene            5143..6042
                     /gene="rmlD"
     CDS             5143..6042
                     /gene="rmlD"
                     /note="OgN14_4"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAV90495.1"
                     /translation="MNILLFGKTGQVGWELQRSLAPLGNLIALDVHSTDYCGDFSNPE
                     GVAETVKKIRPDVIVNAAAHTAVDKAESEPEFAQLLNATSVESIAKAANEVGAWVIHF
                     STDYVFPGNGDTPWLETDATAPLNVYGETKLAGEKALQEHCAKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKEREELAVINDQFGAPTGAELLADCTAHAIRMALNKPEVAGLYHLVAS
                     GTTTWHDYATLVFEEARKAGIPLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFA
                     LVLPDWQVGVKRMLNELFTTTAI"
     gene            6100..6978
                     /gene="rmlA"
     CDS             6100..6978
                     /gene="rmlA"
                     /note="OgN14_5"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="BAV90496.1"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPTPDGLAQAFIIGEEFIGG
                     DDCALVLGDNIFYGHDLPKLMDVAVNKESGATVFAYHVNDPERYGVVEFDKNGTAISL
                     EEKPLQPKSNYAVTGLYFYDNDVVEMAKNLKPSARGELEITDINRIYMEQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDSEQVKVLAEPL
                     KKNAYGQYLLKMIKGY"
     gene            6983..7537
                     /gene="rmlC"
     CDS             6983..7537
                     /gene="rmlC"
                     /note="OgN14_6"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="BAV90497.1"
                     /translation="MNVIKTEIPDVLIFEPKVFGDERGFFMESFNQKVFEEAVGRKVE
                     FVQDNHSKSSKGVLRGLHYQLEPYAQGKLVRCVVGEVFDVAVDIRKSSPTFGKWVGVN
                     LSAENKRQLWIPEGFAHGFLVLSETAEFLYKTTNYYHPESDRGIIWNDQKIGIKWPNV
                     GNLPLLSEKDQAHHGIEYHANENH"
     gene            7568..8722
                     /gene="wzy"
     CDS             7568..8722
                     /gene="wzy"
                     /note="OgN14_7"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAV90498.1"
                     /translation="METIRRRLESKMLFLLLNIVLFISSLTNDKIIFRSSFIFTAVVC
                     SVSFGRGYDWINYYDVYTNIDDYLYNFPFEPGYFYVLRFFNWLNINYPIQNGITTLFL
                     FFCIYSFAKKTNYPSLTFFTIFCFMGHYVLSEQIRQALAICIILLFFDVFRHRKIIKG
                     TLVIFLAMSFHVSAMFCFIYFFMLNDRTRQPNTKFFIVCFIFILMAYSIWLNPNIISF
                     LPLIYKKFVGYTEAYTEGFISISRIVSSKVVLIYLSMLILLFHIYKKSKDRYVFFSTK
                     AIILMIITKLTVFLGRFQYYAIPLLIIGIDNYFYDKKRKGKILIYQLYYSICLFVISL
                     VPLWSPSTFDSINDPILINANSKYIEKKISERCMTLNHYDPENEAIIRCK"
     CDS             8765..9709
                     /note="OgN14_8"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf9"
                     /product="glycosyltranslocase"
                     /protein_id="BAV90499.1"
                     /translation="MNISNINVSAIIPTIGRESLFRSLDSVYKQQFKPTEIIISYDGD
                     NFEEFKNKIEVYLEKINENIPLYLINVGPFSGGNTARQAGINKSVSEYIALLDDDDIW
                     HTDHLLNYVKILCKSQNGKLKLLSCKANIIDITLHNNSIIVPPRLIHSNESIPDYLFK
                     VNNIKADLGFIQSSLILFSKDLALSVPFDINLKYHQDIDWLLRVSQSGIDFEFIQSDL
                     ITVTYYSTPLSVSKKISAVQSLRWSLNNFKDKRCLGDFILTQSYNYARKNGRVVDELY
                     ILYASFVYGKPGIYALARFMLKLFRIDNILKILKKNKK"
     CDS             9717..10808
                     /note="OgN14_9"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf10"
                     /product="glycosyltranslocase"
                     /protein_id="BAV90500.1"
                     /translation="MKRKWVTLFERYENFHFYKDVGQLPYNAHELLNYDVELWCKFRE
                     DYIYDDKKLKIVPIYSSGCNTKVSINIIKKLIKEAKDIDVLNLFHFRSYSLMYAAIYK
                     IFNRKGKVVIKCDGSDQEFPYNNRSLNGKLIFKILKKGKFVDLVLAEHLSLYSYFLQK
                     KIMTLHCPNGVSPEYYGQGLMTKTRNSNIIFVGKCGDVRKNAELAIKAVSKLKSECRI
                     FFLGGETSDFRTWFNDWIKTFPENVKKRFVFLGYINDPMKVISYYDSALIFLMTSKHE
                     GYPLSLAQAMWRCCFPVISEYSGGNDIQAAGCAEIYHDLDELVNILEKKISNSGETLD
                     LAIKARDYALLNNDWRKKLQKIQECLYDE"
     gene            10801..12066
                     /gene="wzx"
     CDS             10801..12066
                     /gene="wzx"
                     /note="OgN14_10"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen flippase"
                     /protein_id="BAV90501.1"
                     /translation="MNKQILKTASLYTGFSIINQFIGLLVQLILMRGSTIIDYGEYAI
                     NFEALALIQLVLANAYRNYYLQKIREDNSHENINKLIYYQAINGSLLIFLFSSIVCYV
                     YKLKLDVSIFLISVSVISSLLLPLQAKWLANNERSKLIIKDISISLLSLVVVYITMRI
                     MHYSVSVVTIFQYVGIGWVSLLLFIITAKGALKKIHYSEIRAISRTFDKKLYVFIMIF
                     IVNALHNKFGGIFLRNFSTEIETSLYLTAFKFINPLFFIQTSLVSAFMPSFVRDKEFN
                     FSGKVFLTFAVPGLLIALSLYLLFPDAIGFLGLKKYLESYQIIKIACLFVFIVFIYGS
                     MSNYISVTGGQRFILVTNVMALITLCLLSFVFKDIGNTSLNLIRIFVLVECLVCVLYF
                     FYLLKKMKISFFFFLSPLICILLVFLSLF"
     CDS             12103..12951
                     /note="OgN14_11"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf12"
                     /product="glycosyltranslocase"
                     /protein_id="BAV90502.1"
                     /translation="MLLTIIVVIYGKNFCDSTSLKSLRACQLNNIKLVVYNNGPIFLD
                     SNDCYDLFSDITKRYNFSLEVIQEISNRPLSKVYNHIIEKNMDSEYFMILDDDTEVPI
                     NYFPLRAFQLSYDIGIPMISVSNNHKVIYPEVNGEIITKEGFCEKVKNIKAISSGLVI
                     HNNVIIKIKNSYPDIFDTRFAFYGVDFTFLRRIVELNKLYHFRIYIENALTHSLSRVE
                     GDISQWRYKERVIDVVLTSLLYEKSKVKAWRCIMKLLLVNIIKLRYGVISVICSSIVK
                     KKHPRC"
     CDS             12962..13873
                     /note="OgN14_12"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf13"
                     /product="glycosyltranslocase"
                     /protein_id="BAV90503.1"
                     /translation="MDNIMNKITAIIVTFNPDLTIFGEILERIASQVDSVLLVDNASD
                     NAALLSKTIMLRENVSPVFLDDNIGLAAAQNLAISKIIDKTNFIILFDQDSLIQDNLI
                     KSLLDDAKKIHEKKDVLLGAIGPSFYDPNTMSIYPATIYYGPFIKQVKVFSEPVEATY
                     LIASGCLISADVLREVGLMKDELFIDYIDVEWSLRAKSKGYNLYISPNAKMAHTIGDA
                     RRKFLGRTISIHSPFRRYFLVRNSFYMIRLNYIPLGYKTRECIFNIARILISIIYSDQ
                     KMKTIKSAFYGIIDGIAGRFGPLKRKI"
     CDS             13885..14988
                     /note="OgN14_13"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf14"
                     /product="glycosyltranslocase"
                     /protein_id="BAV90504.1"
                     /translation="MKILYIITKADEIGGAQIHVRDLARRLHNDGNKVTVIVGEDGAL
                     VRQLKELHISVRIVENLVRQISPLNDIKAIFNIRRIIKDYSPDIIGLHSSKAGIVGRL
                     AACRLNIPVVFTAHGWAFAEGISDKKRKLFILIEKILSPFLDKIITVSEQDKKLALDL
                     GVASSEKQVVIHNGMPDITIKRNDFSNSTKVRLISVARFSEQKDHETLFHALKLISTD
                     NWTLTLVGKGPKLENIKKLASDLNIANNILFLGERDDVDNLLSESDVFCLITNWEGLP
                     LSIIEAMRASLPVVATDVGGVSELVDHKKTGLLHSPKNIQELANILDTIINDSDLRYK
                     LGNAGRVKYQNNFTFEHMYYATIDEYNKLIHTK"
     gene            15146..16552
                     /gene="gnd"
     CDS             15146..16552
                     /gene="gnd"
                     /note="OgN14_14"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAV90505.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELSQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRSASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            16774..17967
                     /gene="ugd"
     CDS             16774..17967
                     /gene="ugd"
                     /note="OgN14_15"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAV90506.1"
                     /translation="MFNRKKSELMKITISGTGYVGLSNGILIAQNHEVVALDIVQAKV
                     DMLNKKQSPIVDKEIEEYLATKDLNFRATTDKYDAYKNADYVIIATPTDYDPKTNYFN
                     TSSVEAVIRDVTEINPNAVMVIKSTIPVGFTKSIKERLGIDNLIFSPEFLREGKALYD
                     NLHPSRIVIGERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVA
                     YFNELDSYAESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQS
                     VPNNLISAIVDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRI
                     KAKGVEVIIYEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRD
                     LFGSD"
     gene            18057..19091
                     /gene="wzz"
     CDS             18057..19091
                     /gene="wzz"
                     /note="OgN14_16"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAV90507.1"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLV
                     QLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGS
                     AVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQSLPLAVSYVGETP
                     EGAQKQLAKYIQQVDDQVNEELGKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQ
                     IQEALQYANQAQVTKPQVQQTEDVTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQT
                     RQNLLDIESLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLG
                     RNALRNYNSK"
     gene            complement(19188..19799)
                     /gene="hisI"
     CDS             complement(19188..19799)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAV90508.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPQALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVNITPDCDNDTLLLLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ"
BASE COUNT     6007 a   3627 c   4212 g   5988 t
ORIGIN
        1 tagaggagaa cgtatgccat ttaaaaaact ctcccgacgc accttcctga cggcaagctc
       61 cgcgcttgcc ttcctccata cccctttcgc tcgcgcactt cccgcccgac aaagcgttaa
      121 cattaacgac tacaacccac acgactggat cgcctcattt aaacaagcct tcggcgaagg
      181 gcaaacggtc gtcgtgcctg gcggattggt ttgtgacaat atcaacaccg gcatcttcat
      241 tcctgcaggt aaaacgttac acatccttgg aagcctgcgc ggcaacggca gagggcgatt
      301 tgtcttacag gacggcagcc aggtgacagg ggaggatggc ggcagtatgc ataacatcac
      361 cctggatgtg cgtggttctg attgcaccat caaagggctg gcgatgagcg gctttggccc
      421 agtaacgcag atttatatcg gcggcaaaaa caaacgggtc atgcgcaacc tgaccatcga
      481 taacctgacc attagccacg ctaattacgc catcttacgc cagggatttc ataaccagat
      541 tatcggtgcc aacatcacca attgtaagtt cagcgactta cagggggacg ctattgaatg
      601 gaacgtggcg attaacgaca gtgatatttt gatctccgac cacatcatcg agcgcatcaa
      661 ctgtactaac ggcaaaatca actggggcat tggcataggt cttgcgggaa gcacttatga
      721 taataactac ccggaagacc aggcagtgaa aaactttgtc gtggcgaata tcacggggtc
      781 ggattgtcgg cagttgatcc atgttgaaaa tggtaaacat tttgttattc gtaatatcaa
      841 agcccgcaat atcacgccgg atttcagtaa gaaagcaggt attgataacg ccacagtcgc
      901 tatttacggt tgtgacaatt tcgtgattga taatattgaa atgattaata gcgccgggat
      961 gttaatcggc tatggggtaa ttaaaggcaa atatctctcg ataccgcaaa atttccgagt
     1021 gaataatatt cagctggata acacccatct tgcttataaa ttgcgcggta tccaaatctc
     1081 tgccgggaat gctgtctcct ttgtgtcgct aactaacatt gagatgaagc gtgcctcgct
     1141 ggagttacac aacaagccgc aacatctttt tatgcgaaat atcaaagtga tgcaggaatc
     1201 ctctgttgga cccgcattga gcatgaactt cgacatgcgc aaagacgttc gcggcgtctt
     1261 tatggcgaaa gaagaaacac tgctgtctct tgcaaatgtt catgcggtga atgaaagagg
     1321 gcaaagctcc gtcgatatcg acaggattaa tcaccatatt gttaatgtgg aaaagattaa
     1381 ctttagattg ccggaacgga gggagtagat ttgcgaccat tcataaactt actggatata
     1441 atgttctaaa agattataat cctcacacta actgttaaag ctggggctgg gcagcattga
     1501 ctactcaggg aaggtactca tctttatctt gtgtttctta cgtaacaacc agactaaagt
     1561 gatttatgaa cgataacgtt ttgctcatag gagcttccgg attcgtagga acccgactac
     1621 ttgaaacggc aattgctgac tttaatatca agaacctgga caaacagcag agccactttt
     1681 atccagaaat cacacagatt ggcgatgttc gtgatcaaca ggcactcgac caggcgttag
     1741 ccggttttga cactgttgta ctactggcag cggaacaccg cgatgacgtc agccctactt
     1801 ctctttatta tgatgtcaac gttcagggta cccgcaatgt gctggcggcc atggaaaaaa
     1861 atggcgttaa aaatatcatc tttaccagtt ccgttgctgt ttatggtttg aacaaacaca
     1921 accctgacga aaaccatcca cacgatcctt tcaaccacta cggcaaaagt aagtggcagg
     1981 cagaggaagt gctgcgtgaa tggtataaca aagcaccaac agaacgttca ttaactatca
     2041 tccgtcctac cgttatcttc ggtgaacgca accgcggtaa cgtctataac ttgctgaaac
     2101 agatcgctgg cggcaagttt atgatggtgg gcgcagggac taactataag tccatggctt
     2161 atgttggaaa cattgttgag tttatcaagt acaaactgaa gaatgttgcc gcaggttatg
     2221 aggtttataa ctacgttgat aagccagatc tgaacatgaa ccagttggtt gctgaagttg
     2281 aacaaagcct gaacaaaaag atcccttcta tgcacttgcc ttacccacta ggaatgctgg
     2341 gtggatattg ctttgatatc ctgagcaaaa ttacgggcaa aaaatacgct gtcagctctg
     2401 tgcgcgtgaa aaaattctgc gcaacaacac agtttgacgc aacgaaagtg cattcttcag
     2461 gttttgtggc accgtatacg ctgtcgcaag gtctggatcg aactctgcag tatgaattcg
     2521 tccatgccaa aaaagacgac ataacgtttg tttctgagta atgcagacga gtcagagaaa
     2581 aaaggaccag gttggactac gattattcgg aaagaggtac tgattaaatt atcagtatgt
     2641 ggatttccga gtaatccgag taacccagat gctgatggtg tgtagtgtta tcgtaaggtt
     2701 taatcaaagt tatgcttggt atatagccat accgtttggc taacctatga caataattta
     2761 cgcactatca gccacttaga ggtaggaaaa taatgacgaa tttaaaagca gttataccgg
     2821 tagcgggtct tgggatgcat atgttgcctg ccactaaggc gatacccaaa gagatgctac
     2881 cgatcgtcga caagccaatg attcagtaca ttgttgacga gattgtggct gcagggatca
     2941 aagaaatcct cctggtgact cacgcgtcca agaacgcggt cgaaaaccac ttcgacacct
     3001 cttatgaatt agaatctctt cttgaacaac gtgtgaagcg tcaactgttg gcggaagtac
     3061 aatctatctg tccaccgggc gtgacgatta tgaacgtgcg tcagggcgaa cctttaggtt
     3121 tgggccactc cattttatgt gcacgacccg ccattggtga caacccattt gtcgtggtgc
     3181 tgccagacgt tgtgatcgac gacgccagcg ctgacccgct gcgttacaac cttgccgcta
     3241 tgattgcgcg cttcaatgaa acgggacgca gccaggtgct ggcaaaacgt atgccgggtg
     3301 atctctctga atactccgtc attcagacca aagaaccgct ggatcgcgaa ggtaaagtca
     3361 gccgcattgt tgaattcatc gaaaaaccgg atcagccgca aacactggac tcagacatca
     3421 tggccgttgg tcgctatgtg ctttctgccg atatttggcc ggaacttgaa cgcactcagc
     3481 ctggtgcatg gggacgtatt caactgactg atgccattgc tgaattggcg aaaaaacagt
     3541 ccgttgatgc catgctgatg acaggtgaca gctacgactg cggtaaaaaa atgggttata
     3601 tgcaggcgtt tgtgaagtat gggctgcgca acctaaaaga aggggcgaag ttccgtaaag
     3661 ggattgagaa gctgttaagc gaataatgaa aatctgaccg gatgtaacgg ttgataagaa
     3721 aattataacg gcagtgagga ttcgtggcga aagtaatttg ttgcgaatat tcctgccgtt
     3781 gttttatata aacaatcaga ataacaacga gttagcaata ggattttagt caaagttttc
     3841 caggattttc cttgtttcca gagcagattg gtaagacaat tagcgtttga atttttcgag
     3901 ttaagcgcga gtgggtaacg ctcgtcacat cgtaggcatg catgcagtgc tctggtagct
     3961 gtaaagccag gggcggtagc gtgcattaat acctctatta atcaacctaa gagccgctta
     4021 tttcacagca tgctctgaag taatatggaa taataaagtg aagatacttg ttactggtgg
     4081 cgcaggattt attggttctg ctgtagttcg tcacattata aataatacgc aggatagtgt
     4141 tgttaatgtc gataaattaa cgtacgccgg aaacctggaa tcacttgctg atgtttctga
     4201 ttctgaacgc tatgtttttg aacatgcgga tatttgcgat gcagctgcaa tggcacggat
     4261 ttttgctcag catcagccag atgcagtaat gcacctggct gctgaaagcc atgttgaccg
     4321 ttcaattaca ggtcctgcgg catttattga aaccaatatt gttggtacat atgtcctttt
     4381 ggaagccgct cgcaattatt ggtctgctct tgatagcgac aagaaaacta gcttccgttt
     4441 tcatcatatt tctactgacg aagtctatgg tgatttgcct catccagatg aagtaaataa
     4501 taacgaagaa ttacccttat ttactgagac gacagcttac gcgccaagca gtccttattc
     4561 cgcatcaaaa gcatccagcg atcatttagt tcgcgcgtgg aaacgtacct atggtttacc
     4621 gaccattgtg actaactgtt cgaataacta cggcccttat cactttccgg aaaaattgat
     4681 tccgctggta attcttaatg ctctggaagg taaggcatta cctatttatg gcaaagggga
     4741 tcaaattcgc gattggctgt atgttgaaga tcatgcgcgt gcgttatata ccgttgtaac
     4801 cgaaggtaaa gcgggtgaaa cttataacat tggcggacac aacgaaaaga aaaacatcga
     4861 tgttgtgctg actatttgtg atttgttgga tgagattgta ccgaaagagc aatcttatcg
     4921 tgagcaaatt acttatgttg ccgatcgtcc gggacacgat cgccgttatg cgattgatgc
     4981 tgagaagatt agccgcgaat tgggctggaa accgcaggaa acgtttgaga gcgggattcg
     5041 gaagacagtg gaatggtacc tgtccaatac aaaatgggtt gataatgtga aaagtggtgc
     5101 ctatcaatcg tggattgaac agaactatga gggccgcaag taatgaatat cctccttttc
     5161 ggcaaaacag ggcaggtagg ttgggaacta cagcgttctc ttgctcctct gggtaacttg
     5221 attgctcttg atgttcactc cactgattat tgtggcgatt tcagcaaccc agaaggtgtg
     5281 gctgaaaccg tcaaaaaaat tcgcccagat gttattgtta atgctgcggc tcataccgca
     5341 gtagataaag ctgagtcaga acccgaattt gcacaattac tcaatgcgac cagcgttgaa
     5401 tcaattgcaa aagcggctaa tgaagttggg gcctgggtaa ttcatttctc aactgactac
     5461 gtattccctg gaaatggcga cactccatgg ctggagactg atgcaaccgc accactaaat
     5521 gtttacggtg aaaccaagtt agctggagaa aaagcattac aagagcattg tgcgaagcac
     5581 cttatttttc gtaccagctg ggtatatgca ggtaaaggaa acaattttgc caagacaatg
     5641 ttacgtctgg caaaagagcg cgaagaatta gctgtcatta acgatcagtt tggtgcacca
     5701 acaggtgctg aactgctggc tgattgtacg gcacatgcaa ttcgtatggc actgaataaa
     5761 ccagaagtcg caggcttgta ccatctggta gccagtggta ccacaacctg gcacgattat
     5821 gctacgctgg tttttgaaga ggcacgaaaa gcaggtattc cccttgcact caacaagctc
     5881 aacgcagtac caacaacagc ctatcctaca ccagctcgtc gtccacataa ctctcgcctt
     5941 aatacagaaa aatttcagca gaattttgcg cttgttttgc ctgactggca ggttggcgtg
     6001 aaacgaatgc tcaacgaatt atttacgact acagcaattt aatagttttt gcatcttgtt
     6061 cgtgatggtg gagcaagatg aattaaaagg aatgatgaaa tgaaaacgcg taaaggtatt
     6121 attttagcgg gtggttctgg tactcgtctt tatcctgtga ctatggctgt cagtaaacag
     6181 ctgttaccga tttatgataa accgatgatc tattacccgc tttctacact tatgttggcg
     6241 ggtattcgcg atattttgat tatcagtacg ccacaggata ctcctcgttt tcaacaactg
     6301 ctgggtgacg ggagccagtg ggggctaaat cttcagtaca aagtgcaacc gactccagat
     6361 ggtcttgcgc aggcatttat catcggtgaa gagtttatcg gtggtgatga ttgtgctttg
     6421 gttctaggtg ataatatctt ttacggtcac gatctgccga agttaatgga tgtcgctgtt
     6481 aataaagaaa gtggtgcaac ggtatttgcc tatcacgtta atgatcctga acgctacggc
     6541 gtcgttgagt ttgataaaaa cggtacggca ataagcctgg aagaaaaacc gttacaaccc
     6601 aaaagtaatt atgcggtaac cgggctttat ttctatgata acgacgttgt cgaaatggcg
     6661 aaaaacctta agccttctgc ccgtggtgaa ctggaaatta ccgatattaa ccgtatctat
     6721 atggagcagg ggcgtttatc cgttgccatg atgggacgtg gttatgcatg gctggatacg
     6781 gggacacatc aaagtcttat tgaagcaagc aacttcattg caacaattga agaacgtcag
     6841 gggctgaaag tatcctgccc ggaagaaatt gcttaccgta aaggatttat tgattctgag
     6901 caggtgaaag tattagctga accgctgaaa aaaaatgctt atggtcagta tctgctgaaa
     6961 atgattaaag gttattaata aaatgaacgt aattaaaaca gaaattccag acgtattaat
     7021 tttcgaacct aaagtttttg gtgacgagcg tggtttcttt atggaaagct ttaatcagaa
     7081 agtattcgaa gaagctgtag gacgtaaggt tgaatttgtt caggataacc attcgaagtc
     7141 tagtaaaggt gttttacgcg ggctgcatta tcagttagaa ccttatgcgc aagggaaatt
     7201 ggtacgttgc gttgttggtg aggtttttga tgtagctgtt gatattcgta aatcgtcgcc
     7261 tacctttggt aaatgggttg gggtgaattt atctgctgag aataagcggc aattgtggat
     7321 ccctgaggga tttgcacatg gttttttagt gctgagtgag actgcggaat ttttatataa
     7381 aacgacgaat tattatcatc ctgagagtga tagaggaatt atttggaatg atcagaagat
     7441 aggaataaaa tggccaaatg ttggaaattt gccattgtta tcagaaaaag accaagctca
     7501 tcatggaatt gaatatcacg ctaacgaaaa tcactaatga aatcatgtca ggttttttta
     7561 ttatgttgtg gaaaccattc gtagacgatt ggaatcgaaa atgttattcc ttttacttaa
     7621 tatagtactc tttatttcat cattgacaaa tgacaaaata atatttcgtt catcattcat
     7681 ttttacagct gtagtctgta gtgtatcatt tggaagaggt tatgattgga taaattatta
     7741 tgatgtatat acaaatatag atgattattt atataacttt ccatttgaac caggctattt
     7801 ttatgtttta cgttttttta attggttgaa tattaattac ccgatccaaa atggtataac
     7861 aactttattt ttgttttttt gcatttatag ttttgcaaaa aaaacaaatt atccatcatt
     7921 aacatttttt acaatatttt gttttatggg gcattatgtg ctttcggaac aaataaggca
     7981 ggctttagcc atatgtataa ttttattgtt ttttgatgtt tttcgacata gaaaaattat
     8041 aaaaggtaca ttggttattt ttttagccat gtctttccat gtttcggcca tgttctgttt
     8101 tatttatttt ttcatgctca atgataggac tcgacaacca aataccaaat ttttcattgt
     8161 ttgttttatt ttcatcttaa tggcatactc tatatggtta aaccccaata taatatcttt
     8221 cctacccctt atttataaaa aatttgtcgg ttatacggaa gcttatacgg aaggatttat
     8281 atccatatcg cgaattgttt catcgaaagt tgtattaata tatttatcaa tgcttatttt
     8341 gttgttccat atttacaaaa aaagcaaaga tagatacgtt ttctttagta caaaagcaat
     8401 cattttgatg attattacta aacttacagt tttcctgggg cgttttcaat actatgcaat
     8461 tcctttatta ataataggga ttgacaatta tttttacgat aaaaaaagga aaggcaaaat
     8521 cttaatatat cagctgtatt attcaatttg tttatttgta atatctttag tacctctttg
     8581 gagtccttct acatttgatt caataaatga tccgatctta ataaatgcaa attcaaaata
     8641 cattgaaaaa aaaataagtg aaagatgcat gactttaaat cattatgatc cggagaatga
     8701 agcaattata aggtgtaagt aatcacaaga gattaaccaa ctaaatatag aagttgaagt
     8761 gtaaatgaat atatcaaaca taaatgtttc agcaattatt ccgactattg gtagagagtc
     8821 tttattcaga tcacttgatt cagtatataa acaacaattc aaaccaactg aaattattat
     8881 atcttatgat ggagataatt ttgaagagtt taaaaataaa atagaagtat atttggaaaa
     8941 aattaatgaa aatattccat tatatcttat aaatgttggg ccattttctg gaggtaatac
     9001 agcaagacag gcaggaataa ataaatcagt atcagaatat atagcattgc tagatgatga
     9061 tgatatttgg catacagatc acttattaaa ttatgttaaa attttgtgta aatcccaaaa
     9121 tgggaagttg aaattacttt catgtaaagc caatattatt gatataaccc ttcataacaa
     9181 ttcaattatt gtaccaccta ggttaattca ttccaatgaa tcaataccag attatttatt
     9241 taaagtaaat aatatcaaag cagatttagg ttttattcaa tcgtcattga ttctattttc
     9301 aaaagattta gccttatcag ttccattcga tattaattta aaatatcatc aagatataga
     9361 ttggctactg cgagtatctc aaagtggtat tgatttcgag tttattcaat ctgacttaat
     9421 taccgtcact tattattcta cccctctaag cgtgtcgaaa aaaataagtg ctgtacaatc
     9481 acttcggtgg tcattgaata acttcaaaga caaacgttgt ttaggggatt ttatattgac
     9541 acagtcgtat aattatgcgc gtaaaaatgg aagagttgtc gatgagcttt atatactcta
     9601 tgcatctttt gtatatggta agccgggtat atatgcttta gctcgtttca tgttaaagtt
     9661 gtttagaatt gataatatat tgaagatact caaaaaaaac aaaaagtgat tttgatatga
     9721 aaagaaaatg ggttacttta tttgagcgtt atgaaaattt tcatttttac aaagatgtag
     9781 gccagttacc atataatgct catgaattat taaattatga cgtagaatta tggtgtaagt
     9841 ttagagaaga ttatatttat gatgataaaa aattaaaaat agttcctatt tattctagtg
     9901 gttgtaacac taaagtttca ataaatataa ttaaaaagtt gataaaggag gccaaagata
     9961 ttgatgtatt gaatctattt cattttagat catatagttt aatgtatgca gcaatctaca
    10021 aaatatttaa tagaaagggg aaggtagtaa ttaaatgcga tggttcggat caagagttcc
    10081 catataataa tagaagtcta aatggcaaat taatatttaa aatattaaaa aagggtaagt
    10141 ttgttgattt agttttagcc gaacatcttt ctctttatag ctacttcttg caaaaaaaaa
    10201 taatgacgtt acattgccct aatggagtat cgcctgaata ttatgggcaa ggtctaatga
    10261 caaaaacgag aaattcaaat ataattttcg taggtaaatg tggcgatgtt agaaaaaatg
    10321 cagaacttgc aatcaaggct gtttctaaat taaaatccga atgtcgtata ttttttcttg
    10381 gtggcgaaac ttcagatttc agaacgtggt tcaacgactg gatcaagaca tttcctgaaa
    10441 atgtgaaaaa aagatttgtt tttttgggat atataaatga tcctatgaaa gtaatttcct
    10501 attatgattc tgctttaatt tttttaatga cgtcaaaaca tgaaggctac cctttatctc
    10561 tagcacaagc aatgtggcgt tgctgctttc ctgtaatttc ggaatatagt ggaggaaatg
    10621 atatacaagc agcaggatgc gctgaaatat atcatgacct tgatgaactc gttaatattt
    10681 tagaaaaaaa aatatcaaat tccggagaga ctttagattt agcgattaaa gcaagagatt
    10741 atgcattgtt aaataatgat tggagaaaga aattacaaaa aatacaagag tgtttatacg
    10801 atgaataaac aaattttaaa aacagcttct ttatatactg ggttttcgat aattaatcaa
    10861 tttatagggt tgttagtcca gttaattttg atgagaggct caacaataat tgactacggg
    10921 gagtatgcaa ttaatttcga agccctcgcc ctgatacaat tggtattagc taatgcatac
    10981 agaaactatt atttgcagaa aatcagggaa gacaattctc acgaaaatat aaataagctc
    11041 atttattatc aagccattaa tggcagtctt ttaatatttt tatttagtag tattgtatgt
    11101 tatgtttata aattaaaact tgatgtttca atatttttaa tttcggttag tgtaatatct
    11161 tctctgcttc tacctctaca agcaaagtgg ttggcaaaca atgaacgttc aaaattaatt
    11221 attaaagata tttcaatttc gcttttatca cttgtggtcg tatacattac catgaggata
    11281 atgcattatt cagttagtgt ggtaactata tttcaatatg ttgggatagg ttgggtttct
    11341 cttctgctct ttattattac agccaaaggc gctttaaaaa aaattcatta ctctgaaata
    11401 agagctataa gcagaacctt tgacaaaaag ttatatgttt ttattatgat attcattgtc
    11461 aatgcattgc ataataagtt cggaggaatc tttttaagaa atttttctac agaaatagaa
    11521 acttccttat atttaacagc atttaaattt attaacccac ttttttttat acagacttcg
    11581 ctagtctcag catttatgcc ttcgtttgta agggataaag agtttaattt ttcaggtaaa
    11641 gtcttcctta catttgctgt tcccggactt cttatagccc tcagtcttta tttgttattc
    11701 cctgatgcaa ttggttttct tgggctaaaa aaatacttag aatcttacca aattataaaa
    11761 atagcttgtt tgtttgtgtt tattgttttt atctacggct caatgtcaaa ctatatatca
    11821 gtaacgggcg gccaaagatt tatactagta acaaatgtta tggcattaat aacattatgt
    11881 cttttatcat ttgtttttaa agatattggc aacaccagct taaacttaat tagaatattt
    11941 gttttagttg agtgtttagt atgtgtatta tacttttttt atttgctaaa aaaaatgaag
    12001 atctctttct ttttctttct ctcaccttta atttgtatct tattagtttt tttgagctta
    12061 ttttagatag aaataaaaca catcgtaact taagggtact atatgttatt gacaataatt
    12121 gttgtcatct atggcaaaaa cttttgcgat tcaacctcat taaaaagttt aagagcctgt
    12181 caattaaata atattaaatt agttgtttat aacaatgggc ctattttctt ggattcaaat
    12241 gattgttatg atttgttttc tgatataact aagcgttaca attttagctt agaggttatt
    12301 caggaaatat ctaataggcc attgagtaaa gtttacaacc atataattga aaaaaacatg
    12361 gactcagaat attttatgat attagatgat gatacagagg tacctataaa ttatttccct
    12421 ttaagggcat ttcaattgtc ttatgatatc ggtattccta tgatatctgt aagtaataat
    12481 cataaagtta tttatccaga ggtgaatggg gaaattatta ctaaagaagg tttttgtgaa
    12541 aaagtaaaaa atattaaggc aatttcgtca ggtttagtga ttcacaataa tgtaattatc
    12601 aaaattaaaa atagttatcc tgatatcttt gatactcgat tcgcttttta tggagttgat
    12661 tttacatttt taagacgtat agtggaatta aataaattat atcacttcag gatttatatt
    12721 gaaaatgctc taacccattc tctatctaga gtcgaggggg atataagtca atggcggtat
    12781 aaagaaagag tgattgatgt tgttttgacg tctttactct atgagaaaag taaagtaaag
    12841 gcatggcggt gcataatgaa actattatta gttaatataa ttaaattacg ttacggagta
    12901 atttctgtaa tttgtagttc tattgtgaaa aaaaaacacc caagatgtta gaagttatta
    12961 aatggataat ataatgaata aaataactgc gatcattgtt acatttaatc cggatttgac
    13021 tattttcgga gaaatacttg aaagaatagc ctctcaagta gattctgtat tattagttga
    13081 taatgcatct gataatgcag cattattaag taaaactata atgctacgcg aaaatgtatc
    13141 ccctgtgttt ctggatgata atattggcct cgcggctgct caaaatttag ctatttcaaa
    13201 aataatcgat aaaactaatt ttataatatt gtttgatcag gatagtttaa tccaagataa
    13261 tctcatcaag tcattacttg atgatgcaaa aaaaatacac gaaaaaaaag acgtattgct
    13321 gggagcaatt ggcccatctt tttacgaccc caacactatg tctatttacc ctgctactat
    13381 ttattacggc ccatttatta aacaagttaa ggttttttct gagccagttg aagctacata
    13441 tttaatcgcg tcaggctgtc taattagcgc tgatgtatta cgtgaagtcg gattaatgaa
    13501 agatgaactt tttattgatt acatcgatgt tgaatggagt ttaagagcaa agagtaaagg
    13561 ttataattta tatatatcac caaacgcaaa aatggcccat acaattggag acgcgaggcg
    13621 taaatttttg gggcggacaa tatctattca ctcccctttt agacgttact tcttggttag
    13681 aaatagtttt tacatgataa ggttaaatta tattccttta gggtacaaga ctagagaatg
    13741 tatttttaat attgctagga tattaatatc tatcatatat tccgatcaaa aaatgaaaac
    13801 aataaaatcg gctttttatg gaatcattga tggaattgca ggtcgatttg gccctctaaa
    13861 acgtaaaata taaagagaaa tttcatgaaa attttatata taatcacaaa agctgatgaa
    13921 atcggtgggg cacaaattca tgtaagagac cttgctcgtc gtttacacaa tgatggtaat
    13981 aaagttacag taatcgtagg agaggatggt gctttagtta gacaacttaa agagcttcac
    14041 atttcggtgc ggatagtaga aaatttagtt aggcaaattt cgccactaaa tgatataaaa
    14101 gccattttta acatcagaag aataattaaa gattattcac cggatattat tggtcttcac
    14161 tcctctaagg ctggaattgt tggtcgacta gcagcttgtc gattaaatat tccagtagta
    14221 tttaccgctc acggctgggc atttgcagag ggtattagtg acaaaaaaag gaagttgttt
    14281 attctcattg agaaaatact ttctcctttt ttggataaga taattactgt ttccgagcaa
    14341 gataaaaagt tggcgctaga tttaggcgtt gcatcctctg aaaaacaagt cgttattcat
    14401 aacggaatgc ctgatattac tattaagcgc aacgattttt cgaattcaac taaagttcga
    14461 ttaattagtg tagctcgttt ttcagagcaa aaagatcatg aaactttatt tcacgcactc
    14521 aagttaattt ctacagataa ctggacacta actctggttg ggaaaggtcc taagttagaa
    14581 aacataaaaa aacttgcatc tgatttgaat attgcaaata atattctctt tcttggggaa
    14641 agagatgatg tcgataattt attaagtgaa agcgatgttt tctgtttaat aacaaactgg
    14701 gagggattac cattaagtat tatcgaggct atgcgtgcgt ccttgccagt ggtagctaca
    14761 gatgttggag gtgtctctga gttagtagac cataaaaaaa ccggcttgct tcattctcct
    14821 aaaaacatac aagaacttgc taatatcttg gatactatta tcaatgatag tgacttaaga
    14881 tataaattgg gaaatgctgg gagagttaaa taccaaaata atttcacatt tgaacatatg
    14941 tattatgcaa caatagatga atataataaa ttaatacata ctaaatagtt aattacattt
    15001 tgcttgtgtt tgctcttttc taacagtttt aatttcttta atttcaagag ataaatatat
    15061 tagacaagtt attccaatat gagtaaattg gcataacttg tgactttaga ccgcaacccg
    15121 cagtaacccc tgacaggagt aaacaatgtc aaagcaacag atcggcgtcg tcggtatggc
    15181 agtgatgggg cgcaaccttg cgctcaacat cgaaagccgt ggttataccg tctctatttt
    15241 caaccgttcc cgtgaaaaga ccgaagaagt gattgccgaa aatccaggca agaaactggt
    15301 tccttactat acggtgaaag agtttgttga atctttggaa acgcctcgtc gcatcctgtt
    15361 aatggtgaaa gcaggtgcag gcacggatgc tgctattgat tcccttaagc catacctcga
    15421 taaaggcgac atcatcattg atggtggtaa taccttcttc caggatacta ttcgtcgtaa
    15481 ccgtgagctt tctgcagaag gttttaactt cattggtacc ggtgtctccg gtggtgaaga
    15541 aggcgcgctg aaaggtcctt ccattatgcc tggtgggcag aaagaagcct atgaactggt
    15601 tgcgccgatc ctgaccaaaa tcgccgcagt ggctgaagat ggcgaaccgt gcgttaccta
    15661 tattggtgcc gatggtgcag gtcattatgt gaagatggtt cacaacggta ttgaatacgg
    15721 tgatatgcag ctgattgccg aagcctattc tctgctaaaa ggtggcctga accttaccaa
    15781 cgaagaactg tcacagacct ttaccgaatg gaataacggt gaactgagca gctacctgat
    15841 cgacatcacc aaagatatct tcaccaaaaa agatgaagac ggtaactacc tggttgatgt
    15901 gattctggat gaagcagcaa acaaaggtac gggtaaatgg accagccaga gtgcgctgga
    15961 tctcggtgaa ccgctgtcgc tgattaccga gtctgtgttt gcacgttata tctcttctct
    16021 gaaagatcag cgtgttgccg catctaaagt tctctctggc ccgcaagcgc agccagctgg
    16081 cgacaaggct gagttcatcg aaaaagttcg tcgtgctctg tatctgggca aaatcgtttc
    16141 ttacgcccaa ggcttctctc agctgcgttc tgcgtctgaa gagtacaact gggatctgaa
    16201 ctacggcgaa atcgcgaaga ttttccgtgc tggctgcatc atccgtgcgc agttcctgca
    16261 gaaaatcact gatgcatatg ccgaaaatcc gcagatcgct aacctgctgc tggctccgta
    16321 cttcaagcaa attgccgatg actaccagca ggcgctgcgt gatgtcgttg cttatgcagt
    16381 acagaacggt atccctgttc ctaccttcgc tgctgcggtt gcctattacg acagctaccg
    16441 cgccgcagtt ctgcctgcaa acctgatcca ggcacagcgt gactatttcg gtgcgcatac
    16501 ttataagcgc attgataaag aaggtgtgtt ccataccgaa tggctggatt aatctgattt
    16561 aaatcaatta atcaatgcaa ggcccggaga aaacctccgg gcttttttat tatacaaagc
    16621 ggcaggttag ggcctttttt tataatttat agttaaaaac gcgatataat acagcgccgc
    16681 acagcaggat cgctgccttg acagttcatc tacatcagcg ttaaaaatcc cgcagtagat
    16741 gaagttgtgg tggtggatta atgaccactc taaatgttta accggaagaa gtcagagcta
    16801 atgaaaataa caatttcagg aacaggttat gttggtcttt caaatggtat tctgattgcg
    16861 caaaatcacg aagtggttgc actggatatc gttcaggcca aagtggacat gcttaacaag
    16921 aagcagtcac cgattgttga taaggagatt gaagagtatc tggcgactaa agatctcaat
    16981 ttccgtgcta cgacagataa gtatgacgcg tataaaaatg ccgattacgt tattattgct
    17041 acgcctaccg attatgaccc gaaaacaaat tattttaata cctcaagcgt ggaagcggtc
    17101 attcgcgatg tgacagaaat taatcctaat gctgtcatgg tgattaaatc tacaattccg
    17161 gtaggtttca ccaaatcaat taaagaacgt ctgggtatcg ataaccttat tttctctccg
    17221 gaattcctcc gcgaaggtaa agctctttac gataaccttc atccgtcacg tattgtaatc
    17281 ggtgagcgtt cggaacgcgc agaacgtttt gctgcgttat tacaggaagg cgcgattaag
    17341 caaaatatcc cgaccctgtt caccgattca accgaagcag aagcgattaa actgtttgct
    17401 aatacctatc tggcgatgcg cgtagcatac tttaatgaac tggatagcta tgcagaaagt
    17461 ttaggtctga atactcgcca gattatcgaa ggcgtttgtc tcgatccgcg tattggcaac
    17521 cattacaaca atccgtcgtt tggttatggt ggttattgtc tgccgaaaga taccaagcag
    17581 ttactggcga actaccagtc tgtgccgaat aacttgattt cggcaattgt cgatgcaaac
    17641 cgcacgcgta aagattttat tgccgatgcc attttgtcac gcaagccgca agtggtgggt
    17701 atttatcgtc tgattatgaa gagcggatca gataacttcc gtgcgtcttc cattcagggg
    17761 attatgaaac gtatcaaggc gaaaggcgtt gaagtgatca tctacgaacc ggtgatgaaa
    17821 gaagattcat tcttcaactc tcggctggaa cgtgatctcg ccactttcaa acaacaagcc
    17881 gacgtaatta tctccaaccg tatggcagaa gagcttaagg atgtggcaga caaagtctac
    17941 acccgcgatc tctttggcag tgactaacat cctgttatca gggcgatttt cgccctgatt
    18001 ctcttatgtt ccctttgtaa taattcatta tttttatcat ttatcctata gcattcatgg
    18061 cgattatcgc taaactatgg cgacttaaaa ttatttcgtc cgttagggta atgatgagag
    18121 tagaaaataa taatgtttct gggcaaaacc atgacccgga acagattgat ttgattgatt
    18181 tactggtgca gttgtggcgt ggcaagatga caattatcat ctctgtcatt gttgctattg
    18241 ccctggctat agggtatctg gccgttgcca aagaaaagtg gacttccaca gctatcgtta
    18301 ctcaacctga tgtggggcaa atcgctggtt ataccaacgc gatgaatgtg atctacggat
    18361 cggctgtacc gaaagtctcc gacattcagg cttcacttat cggacgttac agcactgcat
    18421 tctcagcatt agcggaaacg ctggataacc aggaagaagc agaaaagctg accattgagc
    18481 ctaccgtcaa aaatcagtca ttacctttag cggtgtctta tgttggtgaa acacctgaag
    18541 gtgctcagaa gcagctggcg aagtatatcc agcaagttga cgaccaggta aatgaagaac
    18601 tgggaaaaga cctgaaagac aacatcgcgc tgcgtatgaa aaacttgcag gattctctga
    18661 aaactcagga agtagttgcg caggagcaga aagatctgcg tatccgtcag attcaggaag
    18721 cgttgcagta tgcgaatcag gcgcaggtga caaagccaca ggttcagcag actgaagatg
    18781 tgacacaaga tacgttgttc cttttgggga gcgaagcgct ggagtcgatg attaagcatg
    18841 aagcgactcg tccgttggtg ttctcaccaa actactatca gacacgtcaa aacctgctgg
    18901 atatcgaaag cttaaaagtt gatgatcttg atattcatgc ttaccgttat gtaatgaaac
    18961 cgacgttacc tattcgtcgc gatagcccga aaaaggcaat cactttgatt ctggcggtgc
    19021 tgctgggcgg catggttggc gcggggattg tgttggggcg taatgctctg cgtaattaca
    19081 actcgaagta atcttttcgg ttttaaagaa aatgggcagg gtggtgacac cttgcccgtt
    19141 ttttttgccg gatgcgacga caatatcgca tccgcttacc ccgcaactca ctgatgccgt
    19201 ttacgcaggt tctcaatcac cgtcgttaag tccagatcct gatcctgcaa tagcaccagc
    19261 aggtgataca tcaaatcaga tgcctcgttg gtcagctcaa agcggtcatg tactgtcgct
    19321 gccagtgcgg tttccacgcc ttcttcgccc actttctgcg caatgcgctt ggtgccgctg
    19381 gcatacagtt tggcggtata ggaggtttcc gggtcggcag atttacgttc ggcgagcagt
    19441 tgttccagtt gatacaggaa cagccactgg tgagcggtgt cgccgaagca gctgctggtg
    19501 cctttgtggc aggtcgggcc gatgggattc gccagcaaca gtaacgtgtc gttgtcgcag
    19561 tccggcgtaa tatttactac gttgaggaaa ttgcccgacg tttcgccttt ggtccacagt
    19621 cgctgtttag tgcgcgagaa gaaggtgact ttgccgcttt cgatggtttt gtccagggct
    19681 tgcgggttca tatagcccag cattaacact tcaccggata ccgcgtgttg cacaatcacc
    19741 ggcataagtc cgtcggtttt ttcccagtcc agttcgcgac gttgttgttc tgttaacata
    19801 tcctgatctc cacgccctgt gttgccaggt acgc
//
