LOCUS       AB924559               24376 bp    DNA     linear   BCT 28-OCT-2015
DEFINITION  Klebsiella sp. 1754/49 DNA, capsular polysaccharide synthesis gene
            cluster, serotype: K19.
ACCESSION   AB924559
VERSION     AB924559.1
KEYWORDS    .
SOURCE      Klebsiella sp. 1754/49
  ORGANISM  Klebsiella sp. 1754/49
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella.
REFERENCE   1
  AUTHORS   Pan,Y.J., Lin,T.L., Chen,C.T., Chen,Y.Y., Hsieh,P.F., Hsu,C.R.,
            Wu,M.C. and Wang,J.T.
  TITLE     Genetic analysis of capsular polysaccharide synthesis gene clusters
            in 79 capsular types of Klebsiella spp
  JOURNAL   Sci Rep 5, 15573 (2015)
   PUBMED   26493302
  REMARK    DOI:10.1038/srep15573
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24376)
  AUTHORS   Pan,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2014) Contact:Yi-Jiun Pan National Taiwan
            University College of Medicine, Department of Microbiology; 1, Sec
            1, Jen-Ai Rd., Taipei 100, Taiwan
FEATURES             Location/Qualifiers
     source          1..24376
                     /organism="Klebsiella sp. 1754/49"
                     /mol_type="genomic DNA"
                     /strain="1754/49"
                     /serotype="K19"
                     /db_xref="taxon:1497799"
     gene            217..1119
                     /gene="galF"
     CDS             217..1119
                     /gene="galF"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose pyrophosphorylase"
                     /protein_id="BAT23387.1"
                     /translation="MKMNMANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVT
                     IMNVRQAQPLGLGHSILCARPVVGDNPFVVVLPDIILDGGTADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGR
                     YVLSADIWAELERTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQA
                     FVTYGMRNLKEGTKFRESIKKMLA"
     gene            1512..2141
                     /gene="cpsACP"
     CDS             1512..2141
                     /gene="cpsACP"
                     /note="orf2"
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase homologue"
                     /protein_id="BAT23388.1"
                     /translation="MNWQLISFFGDSTVLLPSAAALFIVLMLRKTSRLLAWQWSLLFG
                     ITGAIVCASKLAFMGWGLGIRELDYTGFSGHSALSAAFWPIFLWLLSARFSAGLQKAA
                     VATGYILAAVVGYSRLVIHAHSVSEVIAGLLLGAAGSALFLVLQKRTSDPESVNISWG
                     GVACLVMVPLILLHSGSKAPTQSLLGQIATAVGPLDKPFTRTDLHKQAW"
     CDS             3020..4540
                     /note="orfX"
                     /codon_start=1
                     /transl_table=11
                     /product="surface assembly of capsule"
                     /protein_id="BAT23389.1"
                     /translation="MPRALSILVFPSFSLRYDSGAENGSCTMIKIARIAVTLGLLSSL
                     GAQAFAAGLVVNDNDLRNDLAWLSDRGVIHLSLSTWPLSQEEISRALKKAKPSYSSEQ
                     VVLARINQRLSALKADFRVTGYTSTDQPGTPQGFGQTQPADNSLGLAFNNSGEWWDIH
                     LQGNVEGGERISNGSRFNANGAYGAVKFWNQWLSFGQVPQWWGPGYEGSLIRGDAMRP
                     MTGFLMQRAEQAAPETWWLRWVGPWQYQISASQMNQYTAVPHAKIIGGRFTFSPFQSL
                     ELGASRIMQWGGEGRPESLSNFWDGLTGKDNTAANDPNEPGNQLAGFDFKFKLEPTLG
                     WPVSFYGQMVGEDESGYLPSANMFLGGVEGHHGWGKDAVNWYVEAHDTRTNMSRTNYS
                     YTHHIYKDGYYQQGYPLGDAMGGDGQLIAGKVELITEDNQRWSTRLVYAKVNPENQSI
                     NKAFPHADTLKGVQLGWSGDVYQSVRLNTSLWYTNANNSDSDDVGASAGIEIPFSL"
     gene            4686..5819
                     /gene="wza"
     CDS             4686..5819
                     /gene="wza"
                     /codon_start=1
                     /transl_table=11
                     /product="putative capsule polysaccharide export protein"
                     /protein_id="BAT23390.1"
                     /translation="MKKKLVRFSALALAIGFLSGCTIIPGQGLNSLRKNVVELPDSDY
                     DLDKLVNVYPMTPGLIDQLRPETVLARPNPQLDNLLRSYEYRIGVGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNSDGTIFYPYIGKVQVAGKTLSQVRQDIASRLTTYIESPQ
                     VDVSVAAFRSQKVYVTGEVAKSGQQPITNIPLTVMDAINAAGGLAPDADWRNVVLTHN
                     GIDTKISLYALMQKGDLTQNHMLYPGDILFVPRNDDLKVFVMGEVGKQSTMKMDRSGM
                     TLAEALGNAEGMSQAFSDATGVFVIRQLKNDKTGKIANIYQLNAQDASAMVLGTEFQL
                     QPYDIVYVTTAPLVRWNRVISQLVPTITGVHDITETVKYVKDM"
     gene            5816..6256
                     /gene="wzb"
     CDS             5816..6256
                     /gene="wzb"
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="BAT23391.1"
                     /translation="MIMFDSILVVCTGNICRSPIGERLLRTLLPNKKIDSAGTNALID
                     HAADDSAIRISESHGLSLDGHRGKQFTQTLGRQYDLILVMEKHHIEQVCHSGPELRGK
                     TMLFAHWMNQRDIPDPYRKSDEAFVSVYKLIEQAGMLWAQKLNA"
     gene            6272..8434
                     /gene="wzc"
     CDS             6272..8434
                     /gene="wzc"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="BAT23392.1"
                     /translation="MPSVINKNSLKEKDEIDLGRLIGEFIDHRKLIISVSSLFTLLAL
                     LYAIFGTPIYQADALIQVEQKQANAILSNLSQMLPDSQPQSAPEIALLQSRMILGKTV
                     DDLNLQTRIKQKYFPLIGRGFSRLSGEKSGIVTISRLYLPDNGKDESDLLLTVKDSNH
                     YIISNDDFEIEGKVGELLDEKGISLKVDAIDAIPNTQFIITYVSRLKAITDLQEKLAV
                     NDQGKDTGILTISMTGDNPQLIEKIVDSISENYLAQNIARQAAQDAKSLDFLSKQLPQ
                     VRSDLDQAEDKLNQYRRQSDSVDLSLEAKSVLDQIVNVDNQLNELTFRESEISQLYTK
                     EHPTYKALMEKRKTLQDEKLKLNKRVSAMPETQQEILRLSRDVESGRAVYMQLLNRQQ
                     ELNIAKSSAIGNVRIIDNAVTQPKPVKPKKIIIVLIGIFLGIVVSAGIVLLKVLLRRG
                     IETPEQLEELGINVYASIPVAEAFARKKVNDKGWGNRNSEQSQSFLAIENPADLAIEA
                     IRGLRTSLHFAMMEARNNVLMISGVSPNAGKTFVSSNLAAIIAQTGKKVIFIDTDMRK
                     GYTHKLFNVKNDKGLSDILSGKSDINGAVRTIEQANFDYISRGAVPPNPAELLMHRRF
                     GELLNWASERYDIVVLDTPPILAVTDAAIIGNYAGTTLLVARFELNTAKEIDISVKRF
                     EQTGVNVKGCILNGVVKKASSYYGYGYNHYGYSYTDKK"
     gene            8478..9971
                     /gene="wbaP"
     CDS             8478..9971
                     /gene="wbaP"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23393.1"
                     /translation="MLLGCCIISPINLNIFMIREGSMTLLVRNIIVSITLALSDFISF
                     VLSLYISLGILKLAITDYDRLIPYQEIDSWIILHWLLACCCVAWYSMRLRHYFYRKTF
                     WFELKEILRTLVIFAVIEIAVMAFTTWTFSRYIWVLTWVFIMLLLPLARMTTKRILDS
                     FGLWRRDTWIIGNGSNAQEAYKAINSERNLGLVVVGYISSESDVPKGETIGNIPVLPN
                     NPDWLSTVDKKTQFIVAVESNQSEMRNNWLRNFMIKGYRYVSVIPTLRGMPLDSTDMS
                     FIFSHEVMIFRVQQNLAKLSSRILKRIFDIIGAISIIIVLSPLLLYISLKVKKDGGPA
                     IYGHERIGKGGVSFKCLKFRSMVMNSKEVLEELLIRDPMAKKEWDETFKLKNDPRVTK
                     IGGVLRRTSLDELPQLFNVLKGEMSLVGPRPIITAELERYNEEVDYYLLSKPGMTGLW
                     QVSGRSDVDYETRVYLDAWYVKNWSMWNDIAILFKTIGVVLKKDGAY"
     gene            10032..11141
                     /gene="wcuF"
     CDS             10032..11141
                     /gene="wcuF"
                     /note="HG23; orf8"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23394.1"
                     /translation="MKVLHIAETAKGGVGTIINSLMEMDSIESSVLVPDTQCEMILTG
                     KKYLFNRTGRNAISLFKLALESYKLIKKNKPDVIHLHSTFSGMVVRFLYLIHILKKSD
                     VTIVYTPHAFSFLMNVSESRKKIYSIIEKVLTKVTDYIVCTSQYEMDTAILYGINNGK
                     LKVIYNGVNIPIIDDSNLKEEYPLSENAEKIKILFLGRFDYQKGYDILLELIKILDVN
                     KFEFDIIGDSVTGEAFILNKTNVKYHGWLNHSQLEVFFKEADFLVMPSRWESFGLVAV
                     EAQSYGLPVLANNCSSLPEVIDNNNTGILLDFSNIKAVASFISIKDKTFWNSKRCACI
                     KFVENTFLIEKMKLQYFSLYMNEFDYKEGRGSNGK"
     gene            11098..12018
                     /gene="wcmY"
     CDS             11098..12018
                     /gene="wcmY"
                     /note="HG131; orf9"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23395.1"
                     /translation="MSLIIKKVEVVMENKIVSAIIVTYNPDVDVLTTLIEGLEKQISN
                     IIVVDNFSQNVSTIEKINKEFKFIKLDKNIGLASAQNIGIREAFNYSTHIVIFDQDSE
                     ITVDFVANQLKCESLLLSRGIKVSAVGPKFYDKDSGYEYPATVYKGPFIKKIPVVDEP
                     VEATFVIASGSLMRTEVLKDVGLMLDDFFIDFVDVEWCLRASSKGYKCFINPYETMKH
                     SIGDLRIDVFGRKISLHSDFRKFYIYRNGVYMTRLGYVPVGYKIRVFVFNLIRTCIGL
                     VLSKQKSKTLKASIKGWINGMGRFNKKSPL"
     gene            12214..13653
                     /gene="wzx"
     CDS             12214..13653
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAT23396.1"
                     /translation="MGILSNTKWVAVSQLFKIGVQLLNIVVLARLIPPSEYGLMAMAL
                     VVTNFATLVRDLGTSAAIIQRKDLSNQTINAIFWLNVSMGVGIGVIIVILSPLISFLF
                     HQEKLITVLCLLAISFPLASSSSSHLALLERDSKFRSIAFIEITSSATAVILAITLAY
                     MNWGVYSLVIQAITLACMSTFQLWYKSKWRPNVRKIFDFDEIKGLLGFSGNLTLFNFI
                     NYFSRNADSMIIGHYMSSAILGAYSLAYRVMLFPIQNLTFVITRALFPVFSTYQEDNV
                     KLKETYLNTLYYILMLVLPLMIGLMALNEPFVKLVFGDKWNETAFILSWLAPTGIIQA
                     VLSTSGTIFMAKAKTNMLMKLGIIGAILQVGAFIIGAHFNIITFAKLYFFANVINFFP
                     VMLSVMYCINGNLIDLFKKIYPLLICAIALFYIITLLILRVSYFTNINSLSKLFIVSI
                     FSAVVYIIMVFAVNPKLCLSIIRKYNGNH"
     gene            13660..14523
                     /gene="wctW"
     CDS             13660..14523
                     /gene="wctW"
                     /note="HG349; orf11"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23397.1"
                     /translation="MRGNVMVDNLILVVLYNKKIEDSATLMSLLACNTVISSKVIVWN
                     NGPNTISLNDFHEKFEDHGYQFEYVEALNNSSLAMIYNNVLNIPATRYIILDHDSTLN
                     DEYLSDIVHISSNEVGMPKIYSGDALVNPCVNMLPIFNLSKVLPGQLVTTIGSGLVIG
                     NGIASSIRNKFGDVFDERFMLYGVDTTFCYRLHNLHKKNVVKIINGFEHSLSRLESNI
                     ESKETLMFRKKERSCDLGLRIRFYKNGRFKELTSLILSFCKRFILRREQQYSLYIVFY
                     CLFTGAHIRNN"
     gene            14533..15318
                     /gene="wctX"
     CDS             14533..15318
                     /gene="wctX"
                     /note="HG350; orf12"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23398.1"
                     /translation="MSLMDKIVVYTAVTGSYDDLQPVCCVESCFDYICFTDYDFSGKV
                     PSPWKHIRLPKSSFDNKDIARYCKLNPHKLLPMYASSIWIDGNISIKCEIANLAKDIL
                     ASSDVASYQHWWRDATEQEFYECARYGFDFAWQLKSQLQRYYKEGYRSVDFFENNVIF
                     RNHMKQSLILMHDIWWSEYLQGGKRDQYSFTYAAYKAGVHIRSLGMHDPRINKIYFDY
                     FQHAKKRPFKQTIIKIINRIYIFATQWRVSEPKRENALAKKSK"
     gene            15324..16370
                     /gene="wzy"
     CDS             15324..16370
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAT23399.1"
                     /translation="MFMNNNIIRYVIGFSCVFLLSVAAGLRVFGIDRDYYQYVYFYNS
                     ISHNDLSNLPNLEIGFFYIAKINALLGGSLNTFFILYAFLAISIKLFGIYKASPSPLL
                     SFLYYLGGFYFLHEMMQIRIGLAGAFIFLSFYYLTNNDKKRFLLFTFIGLLFHYSVLM
                     SLFMIFISGKKKAGILYLILPASALVFSLFNSFLSNILDSILIYFPSFIYAKVSMYIY
                     TQENYGANRALIIYGFGAVFIYVTMFFLWFRLRNAMLDEYYVRLNFLIKSTSLVLTIS
                     LFLSFNIELSNRFYSYLGLLCFCLLPAYVINEFKQKIIVILILLIVPLKQFYTSYNEL
                     LANEKDAIYNNIRY"
     CDS             16474..18507
                     /note="HG352; orf14"
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="BAT23400.1"
                     /translation="MNRSRRLLMRGIGYLTLFPLLFLFSKKVSSAPNGLTEKVKNRKI
                     EKDVSELPNQISYLEDIYSLVPRIDGQLITSKHAIKSGPLLNSQIFYDKDDTVSTADG
                     YSVFVSHDKLRWKADVSNGVDVRLAGLLSDGSNLGSCINKIILGEIAKVKAGKSIFEC
                     VTTIYIPSKFNGRANPNYILDEPIVLPSFFCLKTNGFVYISVPDNITYAIKVTNDILD
                     FSTNTLDKSPTDIQGCKTFDAGGGRFVFSGSGSHNSTTGLYIGNQRQHSFAVRDLLIN
                     DITLQYFENGIEFAPNNNFINTFDKINVVMCKYGFLVSADNSVSAGEKIVFNDCVFGN
                     NDIAHFRLAAQVNYYIINCSLDYTGQHVFFIDETCALSRLIIDKGHIEGVPQYLVYCP
                     KKLPLPLKIQFRDVMLYMNGAIYNSMRQLIFSPEGNCHIIFDGCDWTFINYYEHSPYI
                     SLTGYRDKTDINNRIVINNPLPRVTGLRSNCILPQYKSSLLGAIPISHAKKGASVLNK
                     FVDSSNVIFISETSGVEIIYGDIDDDNAQIIEVISYSNDTVVDLISAFYHSGSIGSFW
                     SGGCSIELVDVKSKHCNMFFIIDSYNENYKKVINFDEYKDAKNNIVESYFSDVIDLNK
                     IFSTAKNANKHSGFIGVWQSVNQPKCAVTFQPKIRIQEFKGVIRVKLPVFWRE"
     gene            18774..20180
                     /gene="gnd"
     CDS             18774..20180
                     /gene="gnd"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate-6-phosphate dehydrogenase"
                     /protein_id="BAT23401.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA
                     ENPGKKLVPYYTVQEFVESLETPRRILLMVKAGAGTDSAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILKQIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLALSNEELAKT
                     FTEWNEGELSSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAQNAGIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRTDKEGVFHTEWLD"
     gene            20403..21467
                     /gene="rmlB"
     CDS             20403..21467
                     /gene="rmlB"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose-4,6-dehydratase"
                     /protein_id="BAT23402.1"
                     /translation="MKILVTGGAGFIGSAVVRHIIENTRDEVRVMDCLTYAGNLESLA
                     PVAGSERYSFSQTDITDAAAVAAQFSEFRPDIVMHLAAESHVDRSIDGPAAFIQTNVI
                     GTFTLLEAARHYWSGLGEEQKQAFRFHHISTDEVYGDLHGTDDLFTEETPYAPSSPYS
                     ASKAGSDHLVRAWNRTYGLPVVVTNCSNNYGPYHFPEKLIPLTILNALAGKPLPVYGN
                     GEQIRDWLYVEDHARALYKVATEGKSGETYNIGGHNERKNIDVVRTICAILDKVVAQK
                     PGNITHFADLITFVTDRPGHDLRYAIDAAKIQRDLGWVPQETFESGIEKTVHWYLNNQ
                     TWWQRVLDGSYAGERLGLNN"
     gene            21494..22363
                     /gene="rmlA"
     CDS             21494..22363
                     /gene="rmlA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyl-transferase"
                     /protein_id="BAT23403.1"
                     /translation="MKGIVLAGGSGTRLYPITQGVSKQLLPIYDKPMIFYPVSVLMLA
                     GIRDILIISTPDDMPSFQRLLGDGSQFGVNFSYAIQPSPDGLAQAFIIGEKFIGNDAC
                     ALVLGDNIYFGQSFGKKLEAAAAKTSGATVFGYQVLDPERFGVVEFDENFKALSIEEK
                     PLKPKSDWAVTGLYFYDNNVVEMAKDVKPSERGELEITTLNQMYLERGDLQVELLGRG
                     FAWLDTGTHDSLIEASQFIHTIEKRQGMKVACLEEIAYRNQWLSAEGVAAQAERLKKT
                     EYGAYLKRLLSED"
     gene            22353..23285
                     /gene="rmlD"
     CDS             22353..23285
                     /gene="rmlD"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-L-mannose dehydrogenase/
                     dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAT23404.1"
                     /translation="MKTEPARPLKENNKMKILLIGKNGQVGWELQRSLSTLGDVVAVD
                     YFDKELCGDLTNLDGIAQTVRTVRPDVVVNAAAHTAVDKAESERELSDLLNDKGVAVL
                     AAESAKLGALMVHYSTDYVFDGAGSHYRREDEATGPLNVYGETKRAGELALEQGNPRH
                     LIFRTSWVYATRGANFAKTMLRLAGEKETLSIIDDQHGAPTGAELLADCTATAIRETL
                     RDPALAGTYHLVASGETSWCDYARYVFEVARAHGAELAVQEVKGIPTTAYPTPAKRPL
                     NSRLSNEKFRQAFGVTLPDWRQGVARVVTEVLGK"
     gene            23300..23854
                     /gene="rmlC"
     CDS             23300..23854
                     /gene="rmlC"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-D-glucose-3,5-epimerase"
                     /protein_id="BAT23405.1"
                     /translation="MNIIKTDIPEVLIFEPRVFGDARGFFFESFSSKVFNEAVGRQVE
                     FVQDNHSQSQKGVLRGLHYQLDPHAQGKLVRCVEGEVFDVAVDIRRSSPTFGKWVGAV
                     LSAENKRQLWIPEGFAHGFMALSDTVQFVYKATNYYAPQSERSIIWNDPEIGIDWPAL
                     SDCALSLSEKDLQAHTLATAEVYK"
     gene            24034..24372
                     /gene="ugd"
     CDS             24034..24372
                     /gene="ugd"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAT23406.1"
                     /translation="MKITISGTGYVGLSNGVLIAQNHEVVALDIVQAKVDMLNQKISP
                     IVDKEIQEYLAEKPLNFRATTDKHDAYRNADYVIIATPTDYDPKTNYFNTSTVEAVIR
                     DVTEINPRSG"
BASE COUNT     6966 a   4594 c   5589 g   7227 t
ORIGIN
        1 gagaataatc ttattttcgt tctgaataac ctgaacgaaa ataagattat tctcacttct
       61 gactgttggt aaaagggagt tgtgtgtatt cttttacgtg acagtgaatt taagaatttg
      121 gcgggcagat gcccgggcag tatccgtgta ttatcagttc caatggattt gtgacatgta
      181 caattttgca aaaccgcgtg ttttgcaacc aaacaggtga agatgaatat ggcgaatttg
      241 aaagcggtta ttccggtcgc aggactaggc atgcatatgc tgccggccac aaaggcaatt
      301 ccaaaggaga tgctgccgat cgttgataag ccaatgattc agtacatcgt tgacgaaatc
      361 gtcgccgccg ggatcaaaga gattgttctg gtgacgcact catcgaagaa cgcggtggaa
      421 aaccacttcg acacctccta cgagctggaa gccctgctgg aacagcgcgt gaagcgccag
      481 ctgctggcgg aagtgcaggc catttgcccg ccgggcgtga ccatcatgaa cgtgcgtcag
      541 gcgcagccgc tgggcctggg ccactccatc ctctgcgccc ggccggtagt cggcgacaac
      601 ccgtttgtgg tggtcctgcc ggatatcatc cttgacggcg gcaccgctga cccgctgcgc
      661 tataacctcg ccgctatgat cgcccgcttt aacgagaccg gccgcagcca ggtgctggcg
      721 aaacgcatgc cgggcgatct ctccgaatac tccgtcatcc agaccaaaga gccgatggtg
      781 gctgaaggcc aggtggcgcg tatcgtcgag tttattgaaa aaccggacga gccgcagact
      841 ctggactccg atctgatggc ggtggggcgc tacgttctgt cggcggatat ctgggccgaa
      901 ctggaacgta ccgagccggg cgcatggggc cgtatccagc tgaccgacgc cattgccgaa
      961 ctggcgaaga agcagtccgt cgacgcgatg ctgatgaccg gcgaaagcta tgactgcggg
     1021 aagaaaatgg gctacatgca ggccttcgtt acctacggaa tgcgtaacct gaaagaaggc
     1081 accaaattcc gcgaaagcat taaaaaaatg ctggcctgag cgccagcgta gtgccggggg
     1141 gcagggcgtg aacattcgtc ctgccgctca taacgttatg cagaaattat tcataacgtg
     1201 aatgttataa cgattgtaaa gaaacgtatg gcttcggaga cttctggtag tttgtctctg
     1261 gcctctgtgg tgcaatggtc ggagtagcgg caataatgct ttatgaatag tcacttagta
     1321 cgacaattcc taaagcgcag ggaaagcggt caacgacagc caaaaataaa acttgactgc
     1381 gatcatgttt ccgctttaaa catctcactt gcatgcataa aaatgtgaaa tgaattggca
     1441 tgcgagctgg tacagacatt acggataatc cctgagcacg gcagtggaca tcatcgaagg
     1501 atcacaggta tatgaactgg caactcatct cattttttgg cgatagcacc gttttgctgc
     1561 caagcgcagc ggcgctgttt attgtcctga tgctgcgtaa aacgtcgcgt ttgctggcgt
     1621 ggcagtggag tttgctgttc ggcatcaccg gcgctatcgt ctgcgcctcc aaactggcct
     1681 ttatgggctg gggtctgggt attcgcgagc tggattacac cggcttcagc ggccactccg
     1741 cgctctccgc ggccttctgg cctatctttc tgtggctgct cagcgctcgt ttttccgcgg
     1801 gtttgcaaaa agcagccgtc gccaccggct atattctggc cgccgtggtg ggctattcgc
     1861 ggctggtcat ccatgcgcat tccgtctcgg aagtgattgc cggcctgctg ctgggcgctg
     1921 ctggcagcgc tttgttcctg gtgttgcaaa aacgtacctc tgatccggaa agcgtgaata
     1981 tctcatgggg cggtgtcgca tgcctggtga tggttccact tatcctgtta catagcggta
     2041 gcaaagcgcc gactcagtcc ctgctgggac aaatcgccac cgcggtgggg ccgctggata
     2101 aaccctttac gcgtaccgat ctccacaagc aggcctggta atcgccattt gttttacagg
     2161 ggaaattaag ttttcgccgg ttaattagac aaataagaaa atattctact atatatccgg
     2221 taattgataa ttcatattta tgaaataatg aagtgctact acattgttat tgcatatttg
     2281 tctggatata gctttgatca gacgtttctt aaatgcgctg agacgttacc tgaggcacat
     2341 tcaatgaata tccagacaca ggaaactatt agaaattgta gttgactata acgccatcat
     2401 ctgatttttg catgatgatg agctatgtaa aaagacgttt ttttacagtc agttagctgc
     2461 atgtgtgatg ctgtagcagt accgggaaga tctctaaccc tggaaatcag tgaataatct
     2521 taattggtga cccgcttatt ttttgtcagt agaacgacag acggcattaa ttggcagata
     2581 ttcggtaaca acactcccaa ttgtgaccga aatcccgtaa acttaacgcc gccaaaaata
     2641 atggcctgac caattattca tccacaggtc gataaaaatt aagtcgttca gatagtcagt
     2701 gcgctggtag ctgttaagcc aggggcggta gcgtcgctga agccgcttgc tgttgcacag
     2761 aggttctctt caacggctgt aaatatcgac ccggtcagga tgatcatcat caatagatat
     2821 ctatcaattt tctacggata tcctcagaag ttggccagga gcggctgctg atatcgcctg
     2881 gacattaact ttcctgtctc atccatagcc tgtagggtaa aattcgccta cattgtgagc
     2941 tgagtggatg ttataaggct aacaagcagc ttagggtaaa tgtacttgcc tcgccggtgt
     3001 tgcacagcga agtcagctgg tgccgcgagc gctttctatc ttggtattcc cctcattctc
     3061 attgagatac gacagcgggg ctgaaaatgg atcttgtaca atgataaaaa ttgcgcgcat
     3121 tgccgtgacg ttgggtttgc tttcctcact gggagcccag gctttcgcgg ccgggttagt
     3181 ggtaaatgac aacgacttgc gtaacgacct ggcctggctt tccgatcgcg gggtcatcca
     3241 tctgagcctg tcgacctggc cgctgagcca ggaagaaatc tcccgggcgc taaaaaaggc
     3301 caaaccgtcc tattcttctg agcaagtggt gctggctcgt attaaccagc gactgtctgc
     3361 cttaaaagcg gatttccggg ttaccggcta cacttcaacc gatcagccgg gcactccgca
     3421 ggggtttggt cagacacagc cggcagataa ctcgttaggc ctggcgttca acaacagcgg
     3481 cgagtggtgg gatatccacc tccagggcaa cgtcgaagga ggggagcgga tcagcaacgg
     3541 atcgcgcttc aacgccaacg gcgcatacgg cgcggtgaag ttctggaacc agtggctctc
     3601 ttttggtcag gttccgcagt ggtggggacc gggctatgaa ggtagcctga tccgcgggga
     3661 tgccatgcgg ccgatgaccg gtttcctgat gcagcgcgca gagcaggcag cgccggaaac
     3721 ctggtggttg cgctgggtcg gcccatggca gtaccagatc tccgccagcc agatgaatca
     3781 atataccgcg gtaccccatg ccaaaattat cggcggtcgt tttacctttt caccattcca
     3841 gtctttagaa ttaggcgcat cacgcattat gcagtggggt ggggaagggc ggcctgaatc
     3901 actcagtaac ttctgggatg gtttaacagg caaggataat accgccgcaa acgatcccaa
     3961 tgaaccaggg aaccaactgg ccggttttga ctttaagttc aaactcgagc cgactctagg
     4021 gtggccggtg agtttctatg ggcaaatggt cggcgaggat gagtcaggct acctaccatc
     4081 ggcgaatatg ttccttggtg gagtggaagg gcaccacggt tggggtaaag atgcggtgaa
     4141 ctggtacgtg gaagcgcatg atactcgtac caatatgagc cggacgaatt acagctatac
     4201 ccaccacatc tataaagatg gttattacca acaagggtat ccactggggg atgcgatggg
     4261 tggggatggt caactcattg ccgggaaggt tgagctgatt actgaagata accagcgctg
     4321 gagtacgcgc ctcgtttacg ccaaggttaa cccggagaac cagtcgatca acaaagcatt
     4381 cccacatgcc gataccttga aaggtgtaca gctaggctgg agcggggatg tttatcagtc
     4441 tgttcgtctg aatacctctt tgtggtacac caacgctaac aacagcgaca gcgatgacgt
     4501 tggggcaagc gcagggatag aaataccgtt tagtttataa ggctgaatgc tgaaaataga
     4561 ggagagaggg tggtagtgct gcaggaggca gtcagttttt atctctccac aagccggcag
     4621 gtaagcaacg gcgatgacag ctgctcagga attggcaaat tttgatttac tgatgatgtg
     4681 acattatgaa gaaaaaactt gttagatttt cggcattagc gttggcaatt gggtttttat
     4741 cgggttgtac aatcatccct ggtcagggat taaacagtct gcgcaagaac gtggttgagc
     4801 ttccagacag cgactacgat ctggataagt tagtgaacgt gtatccaatg acaccaggcc
     4861 tgatcgatca actccgtccg gagacagtac tcgctcgtcc aaatccgcag ctggataatt
     4921 tactacgcag ttatgaatat cgcatcgggg ttggcgacgt attaatggta accgtttggg
     4981 atcacccgga gctgacaaca ccggcaggtc agtaccgtag cgccagtgac accggtaact
     5041 gggttaactc cgatggtacc attttctatc catatattgg taaggttcag gtggcgggca
     5101 aaacgcttag ccaggtacgc caggatatag ctagtcgttt aaccacttat attgagagcc
     5161 cgcaggttga tgtaagcgtt gcggccttca gatctcaaaa agtatatgtg actggtgaag
     5221 ttgcaaaatc tggtcagcag ccaattacca atattccgtt aacagtcatg gatgcgatca
     5281 atgctgctgg tgggctggca ccggatgcag attggcgaaa tgttgtacta acgcacaatg
     5341 gaatagatac taaaatctct ctatatgcat taatgcagaa aggtgatctt acccaaaatc
     5401 atatgcttta tccgggagat attttatttg taccacgtaa tgatgacctt aaagttttcg
     5461 tcatgggtga agtcggtaaa cagagcacga tgaagatgga tcgtagtggc atgactcttg
     5521 ctgaagcatt gggtaatgct gaaggtatgt ctcaagcttt cagcgatgca acaggtgttt
     5581 ttgtaatacg ccaattaaaa aatgataaga ccggtaaaat tgcaaatatt tatcaattga
     5641 atgctcaaga tgcctcagcc atggtgcttg gtactgaatt ccaattacaa ccttatgata
     5701 ttgtatacgt cactacagca ccattggttc gctggaatcg tgtaatatca caattagttc
     5761 ctacaatcac aggggtacat gatattacag aaactgtgaa gtacgttaag gatatgtgat
     5821 tatgtttgat tcgatacttg ttgtttgtac aggaaatatc tgtcgttcgc cgatcggcga
     5881 gcgtttgctg aggacattat tgccaaataa aaagatagat tcagcgggta caaacgcttt
     5941 aattgatcat gctgccgatg atagtgcaat aaggatttct gaaagccatg gcctttcttt
     6001 agatggccat cgaggtaaac agtttaccca gacacttggg agacaatatg atttaatttt
     6061 ggttatggaa aaacaccata tcgagcaggt atgccatagt ggtccagaat tgcgcggaaa
     6121 aaccatgctt ttcgctcact ggatgaatca gcgtgatatt ccagacccat atcggaaaag
     6181 tgatgaggca tttgtatctg tctataaact tattgaacag gctggaatgc tttgggccca
     6241 aaaattaaat gcataattca ggaatagacg catgccatca gttataaata agaattccct
     6301 taaagaaaaa gatgagattg atttaggacg cctgatcggt gaatttatag atcatcgaaa
     6361 gcttattatt tctgtgagct cacttttcac tctcttagca ttgctgtatg ctattttcgg
     6421 gacaccgata tatcaggctg atgcattaat tcaggtcgag cagaaacaag caaatgcaat
     6481 tcttagtaat ttgagtcaaa tgttaccgga tagtcaacca caatccgccc ccgaaatagc
     6541 attacttcaa tccagaatga tattagggaa gacagttgat gatcttaatt tgcaaacgcg
     6601 tattaagcag aagtacttcc ctttaattgg tagagggttt tcacgcttat ccggggaaaa
     6661 aagtggtatt gtaacaattt ctcgcttgta tttgcctgat aatggtaagg atgaatctga
     6721 cttactattg actgtaaaag attcgaatca ttacattata tcaaatgatg attttgaaat
     6781 tgaaggcaaa gttggggaat tattggatga gaagggaatt tcccttaaag ttgatgcgat
     6841 agatgcaatt cctaatactc agtttattat aacatatgta agtcgtttaa aagcaataac
     6901 agacttacaa gaaaaactgg cagtaaatga ccaaggcaaa gacactggca tactaacaat
     6961 atctatgaca ggtgataacc cacagttaat agaaaaaatt gtggatagca ttagtgagaa
     7021 ttatttagct caaaatattg caagacaggc cgctcaagat gcgaaaagtt tagatttttt
     7081 aagtaaacag ttaccccaag tccgcagtga tttagatcag gcggaagaca aacttaatca
     7141 atatcggaga caaagtgatt cagtagattt atcgcttgaa gcaaagtctg ttcttgatca
     7201 aattgtaaat gtcgataatc aattaaatga actaacattc cgtgagtcag aaatatcaca
     7261 gctttatact aaggaacatc ctacttataa ggcgttgatg gagaaaagaa aaactttaca
     7321 ggatgagaaa cttaaactta acaagcgcgt tagtgcaatg ccggaaacac agcaggaaat
     7381 acttcgatta agtcgggatg ttgaatccgg tagagctgta tatatgcagc tgttgaatag
     7441 gcaacaagaa ttaaatattg caaaatcaag tgctattgga aatgttcgta ttattgataa
     7501 tgcagttaca cagccaaaac ctgttaaacc taaaaaaata ataattgtcc tcatagggat
     7561 ttttttggga atagttgtat ctgctggaat tgtattatta aaagtactat tacgtcgtgg
     7621 gattgaaacg ccagaacaat tagaagagct tggtataaat gtatatgcta gtatacctgt
     7681 agcagaagca ttcgccagaa aaaaagttaa tgataaagga tggggtaaca gaaattctga
     7741 gcaaagtcag agcttcttgg cgatagagaa tcccgccgat cttgcaattg aggctatacg
     7801 aggtttaagg acaagtttgc attttgcgat gatggaagca cgtaacaatg tgctgatgat
     7861 atctggtgtt agcccaaatg caggtaagac tttcgtcagt tctaatttag cagctataat
     7921 tgcccaaact ggcaagaaag taatattcat tgatacagat atgaggaaag gatatactca
     7981 caaacttttt aatgtaaaaa atgataaagg gctttctgat atcttatctg gtaagtcaga
     8041 tattaatggt gctgttagaa ctatagaaca ggcgaatttt gattatatat ctagaggtgc
     8101 tgtaccacct aatcctgctg agttgttaat gcatcgtcgc tttggtgaat tgctcaattg
     8161 ggctagtgaa agatatgata tagtagtact tgacacacca cctatcttgg ctgttacaga
     8221 tgctgcgatt ataggtaatt atgcgggcac gacattatta gttgccagat ttgaattaaa
     8281 taccgctaaa gagatcgata ttagtgttaa gcgttttgaa caaaccggtg ttaatgtcaa
     8341 aggatgcatt ttgaatggtg ttgtcaaaaa ggcaagtagc tattatggtt atggttataa
     8401 tcattatggt tattcctata ccgacaaaaa atgacatgta aatatattta agcaattacc
     8461 aagagcatga aattttaatg ctcttgggtt gttgtatcat aagtccaata aatttaaaca
     8521 tttttatgat tagagagggg agtatgacgc ttctcgtcag aaatattata gtcagtataa
     8581 cattggcttt atctgatttt atcagttttg tactatcatt atatatttcg ttaggaattt
     8641 tgaagttagc aataacggat tatgacagac ttattccata ccaggaaata gacagttgga
     8701 taatacttca ttggctatta gcttgctgtt gtgttgcatg gtactcgatg agattgcgtc
     8761 attattttta tcgcaaaaca ttttggtttg aacttaaaga aattttgaga acattagtca
     8821 tttttgctgt aatagaaatt gcagttatgg catttaccac atggacattt tcaagatata
     8881 tatgggtact aacatgggtt ttcataatgt tattactccc gctagcgaga atgacaacaa
     8941 agcgaatact tgactctttc ggcttatgga gacgagatac ttggataata ggaaacggat
     9001 ccaatgctca agaggcatat aaagcgataa atagtgagcg taacttaggt ttagtagttg
     9061 ttggttatat ctcatcggag tctgatgtcc caaagggaga aactattgga aatattccag
     9121 tattacccaa caatcctgat tggttgtcga ctgtagataa aaaaactcag ttcattgtag
     9181 cagtagagtc taatcaaagt gaaatgcgta ataattggtt acgcaatttt atgataaaag
     9241 gatatcgcta cgtatcagtt atcccaacat tacgcggtat gccacttgat agcactgata
     9301 tgtctttcat tttcagccat gaagtcatga tttttcgtgt ccaacaaaac cttgcaaagt
     9361 tgtcctctcg aatcctcaag cgaatttttg atataattgg tgctatttca ataataatag
     9421 tattatcacc attattactt tatattagtc taaaagtaaa aaaagatggt ggaccagcaa
     9481 tttatggtca tgagcgtata gggaaaggtg gggtatcatt taaatgccta aaatttagat
     9541 ccatggttat gaattcaaaa gaagttcttg aggaattatt aattcgagac cctatggcaa
     9601 aaaaagagtg ggatgaaaca tttaaattaa agaatgatcc aagagtaacc aagatcggtg
     9661 gcgttttaag gcgtactagt ttagatgaat tacctcaatt gtttaatgtt ctcaaaggcg
     9721 aaatgagttt agttggacct agaccaataa ttacagccga attagagaga tataacgaag
     9781 aagtcgatta ttatctttta agtaagccgg gaatgactgg tttatggcaa gtaagtgggc
     9841 gaagtgatgt cgactacgaa acaagagtat atttagatgc atggtatgtt aaaaactggt
     9901 ccatgtggaa tgatatcgct atccttttta aaactattgg tgttgttttg aagaaagatg
     9961 gagcatatta acactcaatc agtagctgat acagattcaa ataccatcat ggcaaaagga
    10021 agtcttagca gatgaaagta ttgcacattg ctgaaacagc gaagggcggt gtagggacta
    10081 taattaattc tctcatggaa atggattcta tcgaaagtag tgtattagtt cctgatacgc
    10141 agtgtgagat gatattaacg ggaaagaaat atctatttaa ccgaactgga aggaatgcaa
    10201 tttctctttt taagctggca ttggaaagtt ataagctaat aaagaagaat aagccagacg
    10261 tgattcatct acacagtacc ttttcgggga tggttgttag atttttatat ctcattcata
    10321 tattgaaaaa aagtgatgtg actattgttt atactccaca tgcattttca tttttgatga
    10381 atgtttcaga atctaggaaa aaaatttatt caataataga aaaagtatta actaaagtaa
    10441 ctgactatat tgtatgcacc agtcaatacg agatggacac agccatatta tatggaatta
    10501 ataacggtaa attgaaggta atttataatg gagttaatat accaattata gatgattcaa
    10561 atttaaaaga agaatatcca ttaagtgaaa atgcagaaaa aataaaaatt ttatttcttg
    10621 gtcgctttga ttatcaaaaa ggatatgata ttttacttga gttaattaag atattagacg
    10681 tcaacaaatt tgagtttgat ataatagggg actctgttac tggtgaagcg tttatcttga
    10741 acaagacaaa tgtaaaatat catggctggt taaatcatag tcaattagag gttttcttta
    10801 aagaagctga ttttttagtt atgccaagta gatgggaatc gtttggatta gttgcagttg
    10861 aggcgcaatc atatggttta cctgtattag ccaataactg tagttctttg ccggaagtta
    10921 tcgataataa taatactggt atattgcttg atttctctaa tatcaaagct gttgcaagtt
    10981 ttatttctat aaaagataag actttctgga actcaaagag atgcgcttgt ataaaatttg
    11041 ttgaaaatac atttcttatt gaaaaaatga aattacaata tttttctttg tatatgaatg
    11101 agtttgatta taaagaaggt cgaggtagta atggaaaata aaattgtatc agcaattatt
    11161 gttacttata atccagatgt tgatgttctt acgacattaa ttgaaggact tgaaaaacaa
    11221 ataagtaata taattgtggt cgataatttc tcacaaaatg tttcaacaat agaaaaaatt
    11281 aacaaagagt ttaaatttat aaaactagat aagaatatag gattggcgtc cgctcaaaat
    11341 ataggtatca gggaagcttt taattacagc actcacatcg taatattcga tcaagatagt
    11401 gaaattactg ttgatttcgt tgctaaccaa ctcaagtgtg aatctttatt attaagtaga
    11461 ggtattaaag tttctgctgt tggtccaaag ttttatgata aggatagtgg atatgaatat
    11521 cctgctactg tttataaggg accatttatt aaaaaaattc ctgtggttga cgagcctgta
    11581 gaagcgactt ttgttattgc atcaggctca ttgatgcgaa cagaagtttt aaaagatgtt
    11641 ggtttaatgt tagatgattt tttcattgac tttgttgatg tagagtggtg tctgcgagct
    11701 agctctaaag gatataaatg ttttataaat ccttatgaaa ctatgaaaca ttcaattggc
    11761 gatctcagaa tagatgtatt tggtagaaaa atttctttac attcggactt taggaagttt
    11821 tatatatatc gtaatggggt atatatgaca aggcttgggt atgttccagt aggttataaa
    11881 attcgtgtgt ttgtatttaa tttgataagg acatgtattg gcttagtctt aagtaaacaa
    11941 aaaagcaaaa ctctcaaagc atccatcaaa ggatggatta atggtatggg gagatttaat
    12001 aaaaagagcc cactataaaa tcaccatcta tatttagtga attccttatt aaggccaatc
    12061 agtataaaaa tcattgtatt tggtattcta gatgtgttca ttaagatgca ttgattggca
    12121 atatacaatt tagttgtcgt gcatttatat ctttcattaa aaactataaa tgttaatgac
    12181 ttaaattatt ataattatat tcattgaggg gttatgggga ttttatctaa cacaaaatgg
    12241 gttgcggttt ctcaactatt caaaattggc gtacaactat taaacatcgt tgtattagct
    12301 agattgatcc ctccgagtga gtatgggcta atggcaatgg ctcttgttgt tacaaatttt
    12361 gcaacgttag taagagacct aggtacgtct gccgcaatta ttcagcgtaa ggatttgtcg
    12421 aaccaaacta tcaatgctat tttttggcta aatgtgagta tgggcgtggg gatcggagtc
    12481 ataattgtta tcttatctcc attaatatca tttctgttcc atcaagaaaa gttaataaca
    12541 gtactatgcc ttcttgcaat tagttttcct ttagcaagtt catcatcatc acatttagcc
    12601 cttcttgagc gagattcgaa atttagatct atagctttta ttgaaataac atcatctgct
    12661 actgcagtaa tattggcaat tacgttggcg tatatgaatt ggggagtgta tagccttgtt
    12721 attcaagcga taacattagc atgcatgtcg acttttcaat tatggtataa atccaagtgg
    12781 cgtcctaatg taagaaagat atttgatttt gatgaaataa aaggtttatt aggttttagt
    12841 ggtaatttaa ctctttttaa ttttatcaat tatttttcaa gaaatgctga tagcatgatt
    12901 atcggacatt atatgagttc tgctattttg ggggcttatt cattagcata tagggtaatg
    12961 ctttttccga tccagaattt aacatttgtt attacaagag ctttgtttcc tgtatttagt
    13021 acatatcaag aagataatgt taagttaaaa gaaacatatt tgaatacctt gtattatata
    13081 ttaatgcttg ttttaccctt aatgataggt ttaatggcgt taaatgaacc tttcgtaaaa
    13141 ttagttttcg gtgacaaatg gaatgaaaca gcttttattt tatcatggct agcgcctaca
    13201 ggaattattc aagctgtgct aagtacatca ggcactattt tcatggcaaa agcaaaaaca
    13261 aacatgctta tgaagttagg cattattgga gccattctcc aagtgggggc gtttataatt
    13321 ggagctcatt ttaatatcat cacttttgca aaattatact tcttcgctaa cgtcattaat
    13381 ttttttccag taatgttaag cgtaatgtat tgtataaacg gtaatttgat agatcttttt
    13441 aaaaaaatat atcctctttt aatatgcgca atcgcgctat tttatataat aactctttta
    13501 attttaaggg tttcttattt tacgaatatt aatagtcttt cgaagttatt tatcgtaagc
    13561 atattttcag ctgtggttta tataattatg gtttttgctg taaacccaaa attatgcttg
    13621 tccataatcc gtaaatataa tgggaatcat tgatgtggta tgagaggtaa tgtaatggtc
    13681 gataatttga ttcttgtcgt tttatataat aaaaaaattg aagacagcgc taccttgatg
    13741 agtttattag cgtgtaatac tgtaataagc tcgaaagtca ttgtttggaa caatggtcct
    13801 aatactatat ctttgaatga tttccatgaa aaatttgaag atcatggata tcaatttgag
    13861 tatgttgagg ctttaaataa ctcttcatta gcgatgattt ataataatgt attaaacatc
    13921 cctgcaacta ggtacattat ccttgaccat gactcaaccc tcaatgacga gtatttaagt
    13981 gatattgtcc atatttcctc aaatgaagtt ggaatgccca aaatttactc aggagatgcc
    14041 ttggttaatc cctgtgtaaa tatgttacct attttcaatt tatcaaaagt attaccgggt
    14101 caattagtaa ctacgatcgg gagtggatta gttattggga atggtatagc atcatctata
    14161 agaaataaat ttggtgatgt ttttgatgag cgctttatgc tctatggtgt cgacactact
    14221 ttctgttata gattacataa tcttcataag aaaaatgtgg taaaaattat caacgggttc
    14281 gaacactcat tatctcgtct tgaaagtaat attgagtcta aagaaacgtt aatgttcagg
    14341 aaaaaagaac gcagttgtga tttaggactt agaattagat tctataaaaa tgggcgtttt
    14401 aaagaactaa cctctttgat attaagtttt tgtaaaaggt ttattttaag aagagaacaa
    14461 caatattctt tatatatcgt tttctattgc ttatttactg gtgcgcatat taggaataat
    14521 taattatata gggtgagtct aatggataaa atagtcgttt ataccgcagt tacaggtagc
    14581 tatgatgatt tgcaacctgt ttgctgtgtg gagtcttgtt ttgactatat ttgttttacc
    14641 gattacgatt ttagcgggaa agttccttct ccttggaagc atatacgtct accaaaatca
    14701 tcttttgata ataaagatat tgctcgatat tgtaagctta atcctcataa attgcttcct
    14761 atgtatgcaa gtagtatttg gattgatggg aatatttcta ttaaatgtga aattgctaat
    14821 ttagcgaagg atatattagc ttcatcagat gttgcatcat accagcattg gtggcgtgat
    14881 gcgactgaac aagagtttta tgaatgcgct agatatggtt ttgattttgc atggcaatta
    14941 aaatcccaac tgcaaagata ttataaagaa ggttatagat cagttgattt tttcgaaaat
    15001 aatgtaatat ttagaaatca tatgaagcaa tcattaatac tcatgcatga catttggtgg
    15061 agtgaatatt tacagggtgg aaaaagagat cagtactctt ttacatatgc agcgtataaa
    15121 gcaggcgtac atataagatc attaggtatg catgatccaa ggattaataa aatctatttt
    15181 gattattttc aacacgctaa aaaacggccc tttaaacaga ctattatcaa aataatcaat
    15241 cgcatataca tatttgctac tcaatggcga gtctcagaac ccaaaagaga aaatgcttta
    15301 gccaaaaaaa gtaaataatc agggtgttta tgaacaataa tattatacgt tatgtaatag
    15361 gcttttcctg tgttttttta ctttcagttg cagctggact gagagttttt ggtatagaca
    15421 gggattatta ccaatatgtg tatttctaca attcaatctc acataacgat ttaagtaatt
    15481 tacctaattt agaaattggt tttttttata tcgctaaaat caacgcattg ttaggaggta
    15541 gtttaaacac tttttttata ttatatgcgt ttctggctat atctataaag ctcttcggca
    15601 tatataaagc ttcgccttca ccgttattaa gttttctata ttatctggga gggttttatt
    15661 tcttgcatga gatgatgcag ataaggatag gacttgctgg tgcttttatc tttctttctt
    15721 tttactatct aactaataat gataaaaaaa gatttctgtt atttactttc attggtcttt
    15781 tgtttcacta ttccgttctt atgtcattgt ttatgatttt tatttctggt aagaaaaaag
    15841 ctggtattct atatttgatt cttccggcaa gtgcattggt ctttagtctt tttaattctt
    15901 tcctttcaaa tatattagac tctatattaa tatattttcc ttcttttatt tatgctaaag
    15961 tctcaatgta tatatatact caagagaact atggtgcgaa tagagctttg attatttacg
    16021 ggtttggtgc tgtatttatt tatgttacca tgtttttttt atggtttaga ttaagaaatg
    16081 ccatgctcga tgaatattat gttcgtctaa atttccttat aaaatcaacc tcactagttt
    16141 taactatatc tttatttcta tcttttaata ttgagttgtc aaatcgattc tattcttact
    16201 taggcttgct ttgtttctgc ttgttgccgg cctatgttat taatgaattc aaacaaaaaa
    16261 taattgtaat tctgattcta ttaatagttc ctttaaagca attttatact agttacaatg
    16321 aactattagc aaatgaaaaa gatgctatat ataataatat ccgatattga gtttttttgt
    16381 tattaacgtt ttattaagta tggttcaaat gctatggtaa gtaatattgg ttatactatt
    16441 aatgctatta aataaattta tttaggggca tccatgaata gatcaagaag actacttatg
    16501 agaggtattg gttacctaac tttgtttcct ttgctttttt tattttctaa aaaagtatcc
    16561 tctgccccga atggattaac tgaaaaagtt aaaaatagaa agattgagaa ggatgtgagt
    16621 gaattaccta atcagatttc ctatttggag gatatttata gtttggttcc caggattgat
    16681 gggcagctaa taacatcaaa acatgcaata aaaagtgggc cattactaaa tagccaaatt
    16741 ttttatgata aagacgatac ggtaagtacg gctgatggat attccgtttt tgtcagccat
    16801 gacaaattaa gatggaaagc tgatgtatct aatggagtag atgtaagact agcgggtttg
    16861 ctctcagatg gttctaatct tggcagttgt attaataaaa taattctcgg tgaaattgcc
    16921 aaagttaaag ctgggaaatc tatttttgaa tgtgttacta cgatttatat cccctcaaag
    16981 tttaatgggc gtgcgaaccc taattacata ttggatgaac caatagtact tccttctttt
    17041 ttttgcttga aaacaaatgg atttgtttat atctcagttc cagataatat tacttatgct
    17101 ataaaagtca ctaatgatat tcttgacttt tcaactaata cacttgataa gtcccctact
    17161 gatatccaag gatgtaaaac ttttgatgca ggtggggggc gttttgtatt tagtggttct
    17221 ggaagtcata attcaacaac tggtttgtat attggaaacc aacgccaaca tagttttgct
    17281 gtaagggatt tgcttattaa tgatattacc cttcagtatt tcgaaaatgg aattgagttt
    17341 gcacctaata ataattttat taatacattt gataaaatca atgttgtaat gtgcaaatat
    17401 ggatttttag tttcagctga taactcagtt agtgctggtg aaaaaatagt atttaatgat
    17461 tgtgtcttcg gtaataatga catagctcat tttcgtctcg ctgctcaagt aaattattat
    17521 attattaact gttctttaga ttatacaggg cagcatgtgt tttttataga tgaaacatgt
    17581 gccctatcaa ggcttattat cgacaaggga catatagaag gcgttccgca atatttagtt
    17641 tattgtccca aaaaactacc gttaccttta aaaatccaat tccgtgatgt catgctttat
    17701 atgaatggtg caatttataa ctcaatgcgt caattaatct tttcaccaga aggtaattgc
    17761 catataattt tcgatggttg cgattggacc ttcatcaatt attatgaaca ctctccatat
    17821 atttcgctta caggttatag ggataaaact gatattaata atagaattgt aattaataat
    17881 ccactgccta gggttacagg tttaagatca aattgtattt taccacaata taaaagtagt
    17941 ttattgggtg ctattcctat ttctcatgca aaaaagggcg catccgtttt gaataagttc
    18001 gttgattctt ctaatgttat atttataagt gaaacatctg gtgtcgaaat tatctatggt
    18061 gatatagatg atgacaatgc tcaaattatt gaagtgattt cttattctaa tgatacagtc
    18121 gtagacttaa ttagcgcgtt ttatcattct ggttctattg ggtcattttg gagtggtggt
    18181 tgctctatag aattggttga cgttaaatca aagcattgca atatgttttt tattattgac
    18241 tcatataatg agaactataa aaaagttatt aatttcgatg agtacaaaga tgctaaaaat
    18301 aatattgtag agtcctattt ttccgacgtc attgatttaa ataagatatt ttctactgct
    18361 aagaatgcaa ataaacactc tggttttata ggtgtttggc aaagtgttaa tcagccaaaa
    18421 tgtgcggtaa cctttcaacc caaaattcgc attcaagaat ttaaaggggt aattagagtt
    18481 aaattacctg ttttttggcg tgagtgaatt tgtttttgaa ttgtttttat ttcagaagtg
    18541 acctgaaata ttcgtaatgg tatttttatc gtttttgtcg ttcgtttact tttgtgtgag
    18601 tttttacttt gactacgtac ttttattcta aataaagctt tattttcaac tttagctcaa
    18661 aatgatgatt ttcattttgc tatgctaatt actttctttg cgctaaaata tacatcatat
    18721 ttacatttca gctgcgaaca tgtcgcagtg accacacctg acaggagtat gtaatgtcca
    18781 agcaacagat cggggttgtc ggtatggccg tgatggggcg taaccttgcg ctgaacatcg
    18841 aaagccgagg ttataccgtc tccgttttca accgctcccg tgaaaagacc gaagaagtta
    18901 ttgccgaaaa tccaggcaag aaattggttc cttactacac agtacaagag tttgttgaat
    18961 ctctcgaaac accacgtcgt atcctgttga tggtgaaggc cggtgctggc accgacagcg
    19021 ccatcgattc cctgaagcct tacctcgaca aaggcgacat catcattgat ggcggtaata
    19081 ccttcttcca ggacaccatc cgtcgtaacc gtgagctgtc tgctgaaggt ttcaacttta
    19141 tcggtaccgg tgtttccggt ggtgaagagg gggctctgaa aggaccttcc atcatgcctg
    19201 gtgggcagaa agaagcctat gagttagttg ctccaattct gaagcagatc gcggcggttg
    19261 cagaagacgg tgagccatgt gtgacctata tcggtgctga cggtgctggc cattatgtga
    19321 agatggttca taacggcatc gagtatggtg acatgcagct gattgccgaa gcttatgcgc
    19381 tgttgaaagg cggtcttgca ctttccaacg aagagctggc gaaaactttt accgaatgga
    19441 atgaaggtga gctaagcagc tacctgatcg acattaccaa agatatcttc accaagaagg
    19501 atgaagaagg taagtacctc gttgatgtca ttcttgatga agctgcaaac aaaggtaccg
    19561 gtaagtggac gagccagagt tcactggatc tcggcgaacc tctgtctctg atcaccgagt
    19621 ccgtgtttgc tcgctatatt tcttcgctta aagaccagcg tgtagccgct tcgaaagtgc
    19681 tgagtggtcc gcaggcccag ccggccggtg ataaagctga atttatcgaa aaagtgcgtc
    19741 gcgcgttgta cctcggtaaa atcgtctcct atgctcaggg cttctcccag ctgcgtgctg
    19801 cttctgatga atacaactgg gatcttaact acggcgagat cgctaagatt ttccgcgctg
    19861 gctgcatcat tcgtgcgcag ttcctgcaaa agatcaccga tgcttatgcg caaaatgctg
    19921 gcattgctaa ccttttgctg gcgccgtact tcaaacagat cgctgatgac tatcagcagg
    19981 cgctgcgtga tgtcgtagcc tatgccgtgc agaatggtat tccggtaccg acgttctctg
    20041 ccgcaattgc ctattacgac agctatcgtt ccgcagttct gccagctaac ctgattcagg
    20101 ctcagcgcga ttactttggt gcgcacacct ataagcgtac cgataaggaa ggcgttttcc
    20161 acactgagtg gttagattaa tatttatatt attagacctt catgacttta ttggaggtct
    20221 aataaaaagc ttgagtatta tcaagatcta ttatgatgaa tagtgaaaaa ttaagaattt
    20281 cgctatttgt ttttaaagtg ttcctccgat attatcccca tgaaattaca tctcaatcat
    20341 tttaatatgg agatgtatgc aattattttc tttttgcatg agtaatcaaa ggtaaataaa
    20401 atatgaagat tcttgtcacc ggtggcgcag gctttatcgg ctctgccgtg gttcgtcata
    20461 tcattgaaaa tacccgggat gaagtccgcg tgatggactg cctgacctac gccggcaacc
    20521 tcgaatccct ggcgccggtg gccgggagcg aacgctactc gttttcccag actgatatca
    20581 cggatgctgc tgccgtggcg gcccagttca gcgagttccg cccggatatc gtgatgcacc
    20641 tggcggcaga aagccatgtg gaccgttcca ttgatggccc ggcagctttc atccagacca
    20701 acgtgatcgg caccttcact ctgctggagg cggcccgtca ctactggtcc gggcttgggg
    20761 aggagcagaa gcaggctttc cgcttccacc acatctccac cgatgaggtg tacggcgacc
    20821 tgcacggcac cgatgacctg ttcaccgaag aaaccccgta cgcgccgagc agcccgtact
    20881 ctgcctccaa agcgggcagc gaccatctgg ttcgcgcctg gaaccgcacc tacggcctgc
    20941 cggtggtggt gaccaactgc tccaacaact atggtccgta tcacttcccg gagaaactga
    21001 tcccgctgac tatccttaac gccctggcgg gtaaaccgct gccggtatat ggcaacgggg
    21061 agcagatccg tgactggctg tatgtcgagg atcatgcccg tgcgctgtac aaagtggcga
    21121 ccgaaggcaa gagcggcgag acctacaata tcggcggtca taacgagcgt aaaaatatcg
    21181 atgtggtgcg caccatctgc gccattctcg acaaggtggt ggcgcagaag ccgggcaaca
    21241 tcacccactt tgctgacctg atcacttttg tcaccgaccg tccggggcac gacctgcgct
    21301 acgccattga tgccgcgaaa attcagcgcg atctgggctg ggtgccgcag gagacgttcg
    21361 agagcgggat tgaaaaaacc gtgcactggt atctgaacaa ccagacctgg tggcagcgcg
    21421 tgctggacgg ctcctatgcc ggtgagcgtc tgggcctcaa taactgatat ctgactgatt
    21481 aaggaataga tttatgaaag gtattgttct ggccggcggc tccggcacgc gtttatatcc
    21541 gatcactcag ggcgtctcca agcagctgct gccgatctat gacaagccga tgattttcta
    21601 cccggtgtcc gtcctgatgc tggcgggtat tcgcgacatc ctgatcatct ccaccccgga
    21661 cgatatgcct tccttccagc gcctgctggg tgacgggtcg cagttcgggg tgaacttcag
    21721 ctacgccatc cagccgtcgc cggacggcct ggcgcaggcc tttatcattg gcgagaagtt
    21781 catcggcaac gatgcctgtg ccctggtgct gggagataac atctactttg gccagagctt
    21841 cggtaaaaag ctggaagcgg cggcggcgaa gacttccggt gccacggtgt ttggttatca
    21901 ggtgctggat ccggagcgtt tcggggtggt ggagtttgat gagaatttta aggcgctgtc
    21961 catcgaggag aaaccgctga agccgaaatc ggactgggcg gtgaccgggc tctacttcta
    22021 cgacaacaac gtggtggaga tggcgaagga cgtcaagcct tctgaacgcg gagagctgga
    22081 gatcaccacc ctgaaccaga tgtatctgga gcgcggcgat ttgcaggtgg aactgctggg
    22141 gcgcggattt gcctggctgg atacgggcac ccatgacagc ctgattgaag cttctcagtt
    22201 tattcatacc attgagaagc gccaggggat gaaggtcgcc tgtctggaag agatagccta
    22261 ccgtaatcag tggctgtcgg cggaaggggt ggcggctcag gcggagcgtc tgaagaaaac
    22321 cgagtacggt gcctacctga aacgtctgct cagtgaagac tgaacccgca cggccattaa
    22381 aggaaaataa caagatgaag atattactga ttggcaagaa tggtcaggtg ggctgggagc
    22441 tgcagcgctc cctgtccacg ctcggtgatg tggtcgcggt ggattacttt gataaagagc
    22501 tgtgcggcga tctgactaat ctggacggta tcgcgcagac cgtgcgtacc gtccgcccgg
    22561 acgtggtggt gaatgccgcc gcgcacacgg cagtggacaa ggccgaaagc gagcgggagc
    22621 tctccgacct gctgaacgac aaaggggtgg cggtgctggc ggcggagtcg gcgaagctgg
    22681 gtgccctgat ggtgcactat tccacggact atgtgttcga cggcgccggc agccattatc
    22741 gccgggaaga tgaggcaacc ggcccgctga acgtctacgg tgaaaccaaa cgtgccggtg
    22801 aactggcgct ggagcagggc aacccgcgtc acctgatttt ccgtaccagc tgggtatatg
    22861 ccacccgcgg cgccaacttt gccaaaacca tgctccgcct ggcgggtgag aaagagacgc
    22921 tctccatcat tgacgaccag cacggggcgc ccaccggcgc agagctgctg gcagactgca
    22981 cggcgacggc aatccgtgaa acgctgcgtg atccggcgct ggccggtacc tatcatctgg
    23041 tggccagcgg cgagaccagc tggtgcgact acgcccgcta tgtgtttgag gtggcgagag
    23101 cgcacggtgc agagctggcg gttcaggaag tgaagggcat tccgacgacg gcctatccga
    23161 cgccggcgaa gcgtccgctc aactctcgcc tgtcgaatga aaaattccgg caggcatttg
    23221 gggtgactct cccggactgg cgtcagggtg tggctcgcgt ggtaacagaa gtcctgggta
    23281 aataaacggg tggcaaaaga tgaacattat taaaacagat attcctgagg tgctgatttt
    23341 tgaaccgcgc gtgtttggtg atgcgcgggg tttcttcttt gagagcttca gcagcaaggt
    23401 gtttaatgag gctgtgggcc gccaggtgga attcgtccag gacaaccact cccagtccca
    23461 gaaaggcgta ttgcgcgggc tgcactatca gctggatccg cacgctcagg gcaaactggt
    23521 ccgctgcgtg gaaggtgagg tatttgacgt ggcggtggat atccgtcgtt catcgccaac
    23581 ctttggcaaa tgggtgggcg cggtgctcag cgcagagaat aaacgtcagc tgtggatccc
    23641 ggaagggttc gcccacgggt ttatggcgct gagcgacacg gtgcagtttg tctacaaggc
    23701 gacgaactac tacgcgccac agtcagagcg gagcatcatc tggaacgatc cggagatagg
    23761 gattgactgg ccggcgctga gcgactgcgc gctgtcgctg tcggagaaag atctgcaggc
    23821 acatactctg gccactgcag aagtttataa ataattaggt tgtttttcct aaaatggcgg
    23881 gttccaaatg gaactcgtca tgtttattcg tttacaagct tggtcaaccg accgacttga
    23941 cttaccttcc ttctcagcgt aaaaccgcgc acagcattat ttaaattcgt ggctagccgc
    24001 cattacccag ttaactgatt aaagtgtaat cgaatgaaaa ttactatttc cggtacaggt
    24061 tatgttggtt tatcgaacgg tgtcctgatt gcgcaaaacc acgaagtggt ggccctggat
    24121 atcgtacagg ccaaagtgga tatgcttaac cagaagatct ctccgattgt cgataaagag
    24181 attcaggaat atctggcaga aaaaccgtta aatttccgtg ccaccacgga taagcacgac
    24241 gcataccgta atgccgacta cgtgattatt gccacgccga ccgactacga tcccaaaacc
    24301 aactacttca acacctctac ggtggaagcg gttattcgcg atgtcacaga gatcaacccg
    24361 cgttcgggtt gatctc
//
