LOCUS       AB924560               24813 bp    DNA     linear   BCT 28-OCT-2015
DEFINITION  Klebsiella sp. 1702/49 DNA, capsular polysaccharide synthesis gene
            cluster, serotype: K21.
ACCESSION   AB924560
VERSION     AB924560.1
KEYWORDS    .
SOURCE      Klebsiella sp. 1702/49
  ORGANISM  Klebsiella sp. 1702/49
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella.
REFERENCE   1
  AUTHORS   Pan,Y.J., Lin,T.L., Chen,C.T., Chen,Y.Y., Hsieh,P.F., Hsu,C.R.,
            Wu,M.C. and Wang,J.T.
  TITLE     Genetic analysis of capsular polysaccharide synthesis gene clusters
            in 79 capsular types of Klebsiella spp
  JOURNAL   Sci Rep 5, 15573 (2015)
   PUBMED   26493302
  REMARK    DOI:10.1038/srep15573
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24813)
  AUTHORS   Pan,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2014) Contact:Yi-Jiun Pan National Taiwan
            University College of Medicine, Department of Microbiology; 1, Sec
            1, Jen-Ai Rd., Taipei 100, Taiwan
FEATURES             Location/Qualifiers
     source          1..24813
                     /organism="Klebsiella sp. 1702/49"
                     /mol_type="genomic DNA"
                     /strain="1702/49"
                     /serotype="K21"
                     /db_xref="taxon:1497800"
     gene            195..1097
                     /gene="galF"
     CDS             195..1097
                     /gene="galF"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose pyrophosphorylase"
                     /protein_id="BAT23407.1"
                     /translation="MKMNMANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVT
                     IMNVRQAQPLGLGHSILCARPVVGDNPFVVVLPDIILDGGTADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGR
                     YVLSADIWAELERTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQA
                     FVTYGMRNLKEGTKFRESIKKLLA"
     gene            1490..2119
                     /gene="cpsACP"
     CDS             1490..2119
                     /gene="cpsACP"
                     /note="orf2"
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase homologue"
                     /protein_id="BAT23408.1"
                     /translation="MNWQLISFFGDSTVLLPSAAALFIVLMLRKTSRLLAWQWSLLFG
                     ITGAIVCASKLAFMGWGLGIRKLDYTGFSGHSALSAAFWPIFLWLLSARFSVGLRKAA
                     VITGYVLAAVVGYSRLVIHAHSVSEVIAGLLLGAAGSALFLVLQKRTSDPESVNISWG
                     GVACLVMVPLILLHSGSKAPTQSLLGQIATAVGPLDKPFTRTDLHKQAW"
     CDS             2998..4518
                     /note="orfX"
                     /codon_start=1
                     /transl_table=11
                     /product="surface assembly of capsule"
                     /protein_id="BAT23409.1"
                     /translation="MPRALSILVFPSFSLRYDSGAENGSCTMIKIARIAVTLGLLSSL
                     GAQAYAAGLVVNDNDLRNDLAWLSDRGVIHLSLSTWPLSQEEIARALKKAKPSYSSEQ
                     VVLARINQRLSALKADFRVTGYTSTDQPGTPQGFGQTQPADNSLGLAFNNSGEWWDIH
                     LQGNVEGGERISNGSRFNANGAYGAVKFWNQWLSFGQVPQWWGPGYEGSLIRGDAMRP
                     MTGFLMQRAEQAAPETWWLRWVGPWQYQISASQMNQYTAVPHAKIIGGRFTFSPFQSL
                     ELGASRIMQWGGEGRPESLSNFWDGLTGKDNTAANDPNEPGNQLAGFDFKFKLEPTLG
                     WPVSFYGQMIGEDESGFLPSSNMFLGGVEGHHGWGKDAVNWYVEAHDTRSNMSRTNYS
                     YTHHIYKDGYYQQGYPLGDAMGGDGQLIAGKVELITEDNQRWSTRLVYAKVNPENQSI
                     NKAFPHADTLKGVQLGWSGDVYRSVRLNTSLWYTNANNSDSDDVGASAGIEIPFSL"
     gene            4664..5800
                     /gene="wza"
     CDS             4664..5800
                     /gene="wza"
                     /codon_start=1
                     /transl_table=11
                     /product="putative capsule polysaccharide export protein"
                     /protein_id="BAT23410.1"
                     /translation="MKKKLVRFSALALAIGFLSGCTIIPGQGLNSLRKNVVELPDSDY
                     DLDKLVNVYPMTPGLVDQLRPEAVLAKSNPDLDRLLGNYEYRIGVGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNSDGTIFYPYIGKIKVAGKTLSQVRQEIASRLTTYIESPQ
                     VDVSIAAFRSQKVYVTGEVAKSGQQPITNIPLTIMDAINAAGGLAPEADWRNVVLTHN
                     GKDIKISLYALMQKGDLTQNHLLYPGDILFIPRNDDLKVFVMGEVGKQTTLKMDRSGM
                     TLMEAVGRAEGISQAMSDATGIFVIRQLKNNNGGKIANIYQLNAQDASAMVLGTEFQL
                     EPYDIVYVTAAPIVRWNRVISQLVPTITGVHDMTETVRYIKNWN"
     gene            5803..6237
                     /gene="wzb"
     CDS             5803..6237
                     /gene="wzb"
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="BAT23411.1"
                     /translation="MFDSILVVCTGNICRSPMGERYLQSLLPNKKIDSAGTGALVGHE
                     ADPTASRIAQNYGISLSNHCAKQFTSTLGRKYDLILAMEKEHIEKISQIAPEVRGKTM
                     LFGHWAEYKDIPDPYRKSEEVFTLIFELIKQSGDIWAKKLSV"
     gene            6255..8417
                     /gene="wzc"
     CDS             6255..8417
                     /gene="wzc"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="BAT23412.1"
                     /translation="MSSLKNKPENKDADEIDLSRLYGELIDHRKLIISVTAFFTLIAL
                     VYSLFSTPIYQADSLIQVEQKQANAILSNLSQMLPDSQPQSAPEITLLQSRMILGKTV
                     DDLNLQAKIKQNYFPILGRGFSRLSGDKPGIINVSRLYLPKTDDDIPELTLTVIDANK
                     FTIQTDSFEAEVKVGELFEKNNISIKVDEIQAKPGTSFTVEYLSKLKAINDLRDVLTV
                     SDQGKDTGMLTLSLTGDDPVQIRKILDSISNNYLMQNIDRQAAQDAKSLEFLNRQLPQ
                     VRHDLDISEDKLNKYRQQKDSVDLSLEAKAVLDQIVNVDNQLNELTIRESEVSQHFTK
                     EHPTYKALMEKRVTLLEEKAKLNKRVSAMPETQQEVLRLSRDVDSGRAVYMQLLNRQQ
                     ELNIAKSSAIGNVRVIDEAVTQPRPVAPKKILIVIGGIIFGLIVSVAIIALRVFLRRG
                     IESPEQLEVLGINVYASIPVSETFAKNITKGLKSNKKKSLEYDEFLAIQNPADLAIEA
                     IRGLRTSLHFAMMEARNNILMISGASPNAGKTFVSSNLAAIISQTGKKVLFLDADLRK
                     GYTHKLFNVSNENGLSDYLAGKVDIKNCVKQIKTAGFDFISRGMVPPNPAELLMHSRF
                     QNLLSWASDNYDLVIVDTPPILAVTDAAIIGNYAGTTLLVARFEQNTVKEIEVSAKRF
                     EQSGVMIKGCILNGVVKKASSYYGYGYSHYGYSYSNKE"
     gene            8456..9637
                     /gene="wcuD"
     CDS             8456..9637
                     /gene="wcuD"
                     /note="HG19; orf7"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23413.1"
                     /translation="MVDSNFNESDLFMRIMILNSLYYPYRVGGAEISVQLLAEQLVKL
                     ENEVKVITLHDKKEIKTDFVNGVEVTYLPLKNIYWGFPNTTTSKFKKAIWHFIDCYNF
                     EMKKMVSVQIAQFKPDIVHTNNICGFSVSAWDAVKKAKVKLVHTSRDYYLFHPNSTLF
                     KSGKVMSPSSLSVLFWSWFKKIKSNKVDNYIGISKYITNLHKDCGFFKKATSDFIYNS
                     VTPYVPKKNESDKIRIGFIGRLSVEKGFDVYCKVARQYKDVNELKFYAAGNFQAGNDS
                     NLLKKDAIENSVEVLGYMDLAEFLELVDIVILPLKWNEPFGRTVVECALAGKYVITTS
                     MGAMIELAQIMPNVAIINDIEHELDIFQRYTLHQDLADDVKQLFDPDNIAKQYINHYK
                     K"
     gene            9656..10879
                     /gene="wzy"
     CDS             9656..10879
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAT23414.1"
                     /translation="MTLQSFESRLINFSLLLFLLFEFFAGPLRWLFHLLGAELLFSIP
                     KLLILITILVSVLNIIYKRKITKNGLIASISIIYILLVSIVHVELAAGFVAFWGIIPI
                     FLGYHSARIIFESVQNNKTNNIIYFVFYVSCIGVFCNIIFNYPWYDVSYEIAGMDVSS
                     AQMGTTGGYTRYAGFFKSSLQASSNILILLVYIVASTKNKFFILVCFILSLLVSIITI
                     SKTTFALHLILLFYVFMKILPVKLLWRSTLIFAIVVTFFTIMSTNYSFEMNNDPATTM
                     LLGSLNARLTTTWPDGVESILKFGSLTFGAGLGTIGVGSKLGSGTYNPGDSMYLYIIA
                     TGGYILGIYLLGWLYYQSNILNNSAISRFLSMTLIILCLFGISMTTPEYPLMGFALGV
                     IFNSRASNLQYKEAE"
     gene            10876..11877
                     /gene="wcuE"
     CDS             10876..11877
                     /gene="wcuE"
                     /note="HG20; orf9"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23415.1"
                     /translation="MIMKKIVNFDSRWIGEHGIGRFAKEIQDGIPALNRIKVAIKPTS
                     PFDVFFVTLYLMFNRGYYFTPGYNAPFFHLNRTAITIHDLNHIDIDFNSSVLKRLYYN
                     LVLKRACRKARVILTVSEFSKKRICEWAKINQDKVKVVGNGVSKEFNLEVNGLKENYI
                     LSVGNRKKHKNEIAVLNAFCSANIPEAVMLYFTGERSEELLNHAKKLNISNRIKFMGR
                     VDNETLAKLYKGANMLLFPSLYEGFGLPVIEAMACGTPVITSNVTSLPEIAGDAALLV
                     DPINHGDISLAIEKIYYDIALRQKLVEEGLKQVKKFTWQKTINNVKNELETAFTIKL"
     gene            11886..12917
                     /gene="wcuC"
     CDS             11886..12917
                     /gene="wcuC"
                     /note="HG18; orf10"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAT23416.1"
                     /translation="MLKNTMNKLLFSVSIILSLNSPVASSLEIGIGTHFQSYSSTPET
                     YISLIKELGFTSFRDDYPWSKTEGSEGVYSVSKFLKKTDYALLNADRDGLNPLVILDY
                     GNKLYNNGGYPTTERDIQAFANYAGWVSHRYKGKVKYYEIWNEWTIATGMVKYRNQVP
                     SANVYYNLVKKTSEVIKRNDPNAIILAGSINPLDLRARYIDVNDWKWFEQLVNLGILN
                     YIDGVSLHTYSFMNGNPLLRTPQGNLNRIDAFHTYFTKKTGRSIDVYITEAGVTNYDG
                     PGGMDLIQSANFIKEYTSLVKKRSYIKGLWWYDLIDDGTDIKNKEHNFGFFKNNLEPK
                     ASAEFMMAK"
     gene            13190..14341
                     /gene="wbaZ"
     CDS             13190..14341
                     /gene="wbaZ"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23417.1"
                     /translation="MHNLNIGIVADWLVTYAGSEKVIKEFLEVFPESELYSIVDFLSD
                     EDRVNFKGKKATTSFIQKFPFSKVKYQKYLPFMPLAIEQLDVSKHDIILSSSHAVAKG
                     IITGPDQLHISYIHSPIRYAWDLQHQYIKEAGLDKGMKGMVARWLLHKIRLWDCRTSN
                     GVDHFIANSEFISRRIRKVYGRESKVIYPPVDVNRFGLCENKDDYYFTASRMVPYKRM
                     DLIVEAFSQMPDKKLVVIGDGSEMSKIKAKASSNIELLGYQPNSVMQEYMQKAKGFVF
                     AAEEDFGITPVEAQACGTPVIAFGKGGALETVRPCGVNKATGVFFYKQEIKSLVNAVQ
                     EFEKNIDVFNPQHCRENAIRFSEERFKQEITQFVDQKWSAFKNNKQIIY"
     gene            14447..15877
                     /gene="wbaP"
     CDS             14447..15877
                     /gene="wbaP"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23418.1"
                     /translation="MSRLARNFWTSILLAISDFTGFTVAIAFAIFFVKSFMNDGGQII
                     ANSNINDWVILHTCLGICCVAWYSIRLRHYFYRKTFWFELKEILRTLVIFAIIEIAVL
                     SFAYWDFSRYILAVTWIFVLFFVPTFRMLTKKCLNFFGLWKRETIIIGDGNNAVEAWK
                     AINSESNLGFNVTSFVSSTSKDHLKNHINDIPVISLNPKEVTKHFDKRTQFIVALETS
                     ESSIRNDWLREFLINGFRYVSVIPTLRGVPLDSTDMSFIFSHEVMIFRVQQNLAKLSS
                     RILKRLFDIIGSLTIILVSSPLLIYIALKVKKDHGPAIYGHERIGNGGRPFKCLKFRS
                     MVVNSKEVLEQLLNTDPAARKEWDATFKLKDDPRITDIGKFLRKTSLDELPQLFNVLK
                     GEMSLVGPRPIITAELERYSDEVDYYLLSKPGMTGLWQVSGRSDVDYETRVYLDAWYV
                     KNWSMWNDIAILFKTISVVLRKDGAY"
     gene            15921..17183
                     /gene="wcuA"
     CDS             15921..17183
                     /gene="wcuA"
                     /note="HG357; orf13"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvyl transferase"
                     /protein_id="BAT23419.1"
                     /translation="MKILLVGNHTCGNRGDGAILRGLVDSIKQINPDVEVDILSRYAR
                     SSAFLLGTAIKQDVLYSSRMNKNGGLVKKVIWKIKNSILPDILVSHAKGKGFLKYFPL
                     PNNVVEFIKDLEKYDAVIQVGGSFFVDLYGTGQFEHILCSNIAGKPIYLVGHSVGPFE
                     NPKFQHIAKYCFTKAEKIILREDVSLSLMEKDNFNLNNVTLGVDTAFLVDTEKDVNDY
                     AVSHWKKIIKEQKTVALTVRKLAPFDKRLGVSQDEYEASIARIVDYLNQLGYQVIIFS
                     TCTGIESYHSDDRMVALSVKNKVHDSQCCHVVMDEFNDYQLGILLSNCVFTIGTRLHS
                     AIISINFGTPAIAINYEHKSLGVMRGLKMDVLSADVSDVIDGTLINKIEDLIANMADI
                     EISLKNNLQDAKIIGRTMIENILSEIDR"
     gene            17183..18412
                     /gene="wcaL"
     CDS             17183..18412
                     /gene="wcaL"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23420.1"
                     /translation="MKILFFCIRFPLASETFVLNQVISFIKKGYDVKVLSLYPGDTEK
                     VHGDFEKYNIGALIENIFDADEIPGNKLSLIFSRAKIVLKSSSFSIIKAFNFERFKFL
                     SYSLLLPAIFAKLRNNKISADVIIAHFGHCGVLANAIRNIGLINGKLLTVFHGYDIST
                     ISLLKKYKILYKNLFSQGEYFLPISNLWRDKLISMGCDKDKISVIRMGIKIDEFKYEF
                     HARDQSTLNIISVCRLTEKKGLVYAIDACNALKNKGCKFKYKIIGYGELENVLAEKIK
                     ALGLQDYVYLLGFQPQSVVKTALAESNVFLLPSVTASNGDMEGIPVALMEAMASGLPV
                     ISTYHSGIPELIDDHKNGYLCPERNSEAIAKILYEIYEGKDNLSLIASEARDKIYSQF
                     NEEVEFNKIVTLLESIK"
     gene            18409..19734
                     /gene="wzx"
     CDS             18409..19734
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAT23421.1"
                     /translation="MSGIKKQAIWLLGSNTISAILQILQISLLAHHLKLSELGVLAIV
                     NMVLMVAMILQDMGMSSYIVHMQEMTRRDQSTIYWINLLLSFLTGCLVFVASWPIASF
                     YNMPDLTFLVMLASFNFLFLGSLSQYQSHYIKAKKVILLAKIEIISKIISFLFVLFSI
                     LKMDLRTEAVIYGLIINSFARLFLMSLLGDKSWRPTFEFNSAICKPVFKYGIFQLGSQ
                     ILNQFRTQLDVIVIGKMLGADSLGLYSLAKDLIMQPLKLISPVINRLALPRFAEVQNQ
                     SDKLGGAYLRGTSVILLFSMITFFSIYLLGPVIIKILYGSSRMGVFNILPYMLLFGVL
                     RPMGGLTGAVAQANGKTNIEFRWNVIATSIVLGVTTTVFFIPQLWYVSLSLSLSQLLI
                     SFFVFPCFIKPIVDVSFKSYLYKWFPQALCFICLIYIVKFFDLVLYPFW"
     gene            19867..21273
                     /gene="gnd"
     CDS             19867..21273
                     /gene="gnd"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate-6-phosphate dehydrogenase"
                     /protein_id="BAT23422.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA
                     ENPGKKLVPYYTVQEFVESLETPRRILLMVKAGAGTDSAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILKQIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLALSNEELAQT
                     FTEWNEGELSSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAAFIEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAQNAGIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRTDKEGVFHTEWLE"
     gene            21516..22931
                     /gene="manC"
     CDS             21516..22931
                     /gene="manC"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase"
                     /protein_id="BAT23423.1"
                     /translation="MLLPVIMAGGTGSRLWPMSRELYPKQFLRLFGQNSMLQETITRL
                     SGLEIHEPMVICNEEHRFLVAEQLRQLNKLSNNIILEPVGRNTAPAIALAALQATRHG
                     DDPLMLVLAADHIINNQPVFHDAIRVAEQYADEGHLVTFGIVPNAPETGYGYIQRGVA
                     LTDSAHTPYQVARFVEKPDRERAEAYLASGEYYWNSGMFMFRAKKYLSELAKFRPDIL
                     EACQAAVNAADNGSDFISIPHDIFCECPDESVDYAVMEKTADAVVVGLDADWSDVGSW
                     SALWEVSPKDEQGNVLSGDAWVHNSENCYINSDEKLVAAIGVENLVIVSTKDAVLVMN
                     RERSQDVKKAVEFLKQNQRSEYKRHREIYRPWGRCDVVVQTPRFNVNRITVKPGGAFS
                     MQMHHHRAEHWVILAGTGQVTVNGKQFLLTENQSTFIPIGAEHSLENPGRIPLEVLEI
                     QSGSYLGEDDIIRIKDQYGRC"
     gene            22918..24324
                     /gene="manB"
     CDS             22918..24324
                     /gene="manB"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="BAT23424.1"
                     /translation="MVVANFFGTKRRMTQLTCFKAYDIRGELGEELNEDIAYRIGRAY
                     GEFLKPGKIVVGGDVRLTSESLKLALARGLMDAGTDVLDIGLSGTEEIYFATFHLGVD
                     GGIEVTASHNPMNYNGMKLVRENAKPISGDTGLRDIQRLAEENQFPPVDPARRGTLRQ
                     ISVLKEYVDHLMGYVDLANFTRPLKLVVNSGNGAAGHVIDEVEKRFAAAGAPVTFIKV
                     HHQPDGHFPNGIPNPLLPECRQDTADAVRAHQADMGIAFDGDFDRCFLFDDEASFIEG
                     YYIVGLLAEAFLQKQPGAKIIHDPRLTWNTVDIVTRSGGQPVMSKTGHAFIKERMRQE
                     DAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELLCLKNSSLKSLVADRQAAFPASGEI
                     NRKLGNAAEAIARIRAQYEPAAAHIDTTDGISIEYPEWRFNLRTSNTEPVVRLNVESR
                     ADTALMNAKTEEILALLK"
BASE COUNT     7273 a   4669 c   5613 g   7258 t
ORIGIN
        1 tgaataacct gaacgaaaat aagattattc tcacttctta ctgttggtaa aagggagttg
       61 tgtgtattct tttacgtgac agtgaattta agaatttggc gggcagatgc ccgggcagta
      121 tccgtgtatt atcagttcca atggatttgt gacatgtaca attttgcaaa accgcgtgtt
      181 ttgcaaccaa acaggtgaag atgaatatgg cgaatttgaa agcggttatt ccggtcgcag
      241 gactaggcat gcatatgctg ccggccacaa aggcaattcc aaaggagatg ctgccgatcg
      301 ttgataagcc aatgattcag tacatcgttg acgaaatcgt cgccgccggg atcaaagaga
      361 ttgttctggt gacgcactcc tcgaagaacg cggtggaaaa ccacttcgac acctcctacg
      421 agctggaagc cctgctggaa cagcgcgtga agcgccagct actggcggaa gtgcaggcca
      481 tttgcccgcc gggcgtgacc atcatgaacg tgcgtcaggc gcagccgctg ggcctgggcc
      541 actccatcct ctgcgcccgg ccggtagtcg gcgacaaccc gtttgtggtg gtcctgccgg
      601 atatcatcct tgacggcggc accgctgacc cgctgcgcta taacctcgcc gctatgatcg
      661 cccgctttaa cgagaccggc cgcagccagg tgctggcgaa acgtatgccg ggcgatctct
      721 ccgaatactc cgtcatccag accaaagagc cgatggtggc tgaaggccag gtggcgcgta
      781 tcgtcgagtt tattgaaaaa ccggacgaac cgcagaccct ggactccgat ctgatggcgg
      841 tggggcgcta cgtgctgtcg gcggatatct gggccgaact ggaacgtacc gagccgggcg
      901 catggggccg tatccaactg accgacgcca ttgccgaact ggcgaagaag cagtccgtcg
      961 acgcgatgct gatgaccggc gaaagctacg actgcgggaa gaaaatgggc tacatgcaag
     1021 ccttcgtcac ctacgggatg cgtaacctga aagaaggcac caaattccgc gaaagcatta
     1081 aaaaactgct ggcctgagcg ccagcgtagt gccggggggc agggcgtgaa cattcgtcct
     1141 gccgctcata acgttatgca gaaattattc ataacgtgaa tgttataacg attgtaaaga
     1201 aacgtatggc ttcggagact tctggtagtt tgtctctggc ctctgtggtg caatggtcgg
     1261 agtagcggca ataatgcttt atgaatagtc acttagtgcg acaattccta aagcgaaggg
     1321 aaagcggtca acgacagcca aaaataaaac ttgactgcga tcatgtttcc gctttaaaca
     1381 tctcacttgc atgcataaaa atgtgaaatg aattggcatg cgagctggta cagacattac
     1441 ggataatccc tgagcacggc agtggacatc atcgaaggat cacaggtata tgaactggca
     1501 actcatctca ttttttggcg atagcaccgt tttgctgccc agcgcagcgg cgctgtttat
     1561 tgtcctgatg ctgcgtaaaa cgtcgcggtt gctggcgtgg cagtggagtt tgctgttcgg
     1621 catcaccggc gctatcgtct gcgcctccaa actggccttt atgggctggg gtctgggtat
     1681 tcgcaagctg gattacaccg gcttcagcgg ccactccgcg ctctccgcgg ccttctggcc
     1741 tatctttctg tggctgctca gcgcccgttt ctccgtcggt ctgcgtaaag cggccgttat
     1801 taccggctat gttctggccg ccgtggtggg ctattcgcgg ctggtcatcc atgcgcattc
     1861 cgtctcggaa gtgattgccg gcctgctgct gggcgctgct ggcagcgctt tgttcctggt
     1921 gttgcaaaaa cgtacctctg atccggaaag cgtgaatatc tcatggggcg gcgtcgcatg
     1981 cctggtgatg gttccactta tccttttaca tagcggtagc aaagcgccga ctcagtccct
     2041 gctgggacaa atcgccactg cggtggggcc gctggataaa ccctttacgc gtaccgatct
     2101 gcacaagcag gcctggtaat cgccatttgt tatacagggg aaattaagtt ttcgccggtt
     2161 aattagacaa ataagaaaat aatctactat atacccggta attgataatt catatttatg
     2221 aaataatgaa gtgctactac attgttattg catatttgcc tggatatagc cttgatcaga
     2281 cgtttcttaa atgcgctgag acgttacctg atgcacattc aatgaatatc cagacacagg
     2341 aaactattag aaattgtagt tgactataac gccatcatct gatttttgca tgatgatgag
     2401 ctatggaaaa agacgttttt ttacagtaag ttagctgcat gtgtgatgtt gtagtagtac
     2461 cgggaagatt tctaaccctg gaaatcagtg aataatctta attggtgacc cgcttatttt
     2521 ttgtcagtag aacgacaggc ggcattaatt ggcagatatt cggtaacaac actcccaatt
     2581 gtgaccgaaa tcccgtaaac ttaacgccgc caaaaataat ggcctgacca attattcatc
     2641 cacaggtcga taaaaaatta agtcgttcag gtagtcagtg cgctggtagc tgttaagcca
     2701 ggggcggtag cgtcgctgaa gccgcttgct gctgcacaga ggttctcttc aacggctgaa
     2761 aaatcgtccc ggtcaggatg atcgccctca ctagatatct atcagttttc tacggatatc
     2821 ctcagaagtt ggccaggagc ggctgctgat atcgcctgga tattaacttt cctgtctcat
     2881 cgatagcctg tagggtaaaa ttcgcctaca ttgtgagctg agtggatgtt ataaggctaa
     2941 caagcagctt agggtaaatg tacttgcctc gccggtgttg cacagcgaag tcagctggtg
     3001 ccgcgagcgc tttctatctt ggtattcccc tcattctcat tgagatacga cagcggggct
     3061 gaaaatggat cttgtacaat gataaaaatt gcgcgcattg ccgtgacgtt gggtttgctt
     3121 tcctcactgg gagcccaggc ttacgcggcc gggttagtgg taaatgacaa cgacttgcgt
     3181 aacgacctgg cctggctttc cgatcgcggg gtcatccatc tgagcctgtc gacgtggccg
     3241 ctgagccagg aagagatcgc ccgggcgctg aaaaaggcca aaccgtccta ctcttctgag
     3301 caagtggtgc tggcgcgtat caaccagcga ctgtctgcct taaaagcgga tttccgggtt
     3361 accggctaca cttcaaccga tcagccgggc actccgcagg ggtttggtca gacgcagccg
     3421 gcggataact cgttaggcct ggcattcaac aacagcggcg agtggtggga tatccatctc
     3481 cagggcaacg ttgaaggggg agagcggatc agcaacggat cgcgcttcaa cgccaacggc
     3541 gcatacggcg cggtgaagtt ctggaaccag tggctctctt ttggccaggt accacagtgg
     3601 tgggggcctg gctatgaagg tagcctgatt cgcggggatg caatgcgacc gatgaccggt
     3661 ttcctgatgc aacgagccga gcaggcggcg ccagagacct ggtggctgcg ctgggtgggg
     3721 ccatggcagt accagatctc cgccagccag atgaatcaat ataccgcagt gccccatgcc
     3781 aaaattatcg gcggtcgttt cactttctca ccattccagt cactggaatt aggtgcgtcg
     3841 cgcattatgc aatggggtgg ggaagggcgg cctgaatcac tcagtaactt ctgggatggt
     3901 ttaacaggca aggataatac cgccgcgaat gatcccaatg aaccgggcaa ccagctggcc
     3961 ggttttgact ttaagttcaa actggagccg acactaggct ggcctgtaag cttttacgga
     4021 cagatgattg gcgaggatga gtcgggtttt cttccatcgt ctaatatgtt cctcggtggt
     4081 gtcgaagggc accacggctg gggtaaggat gctgttaact ggtacgtgga agcacatgac
     4141 acgcgcagca atatgagccg aaccaattac agttataccc atcatatcta taaggatggc
     4201 tactatcagc agggctatcc gctgggtgac gcaatgggcg gggatggtca gcttatcgca
     4261 ggaaaagttg agcttattac ggaggataac cagcgctgga gcacgcgctt agtatacgcg
     4321 aaggttaacc ctgagaatca gtcgatcaac aaagcgttcc ctcatgcgga tactctgaaa
     4381 ggtgtacagc tgggctggag cggagatgtt tatcggtcag ttcgtttgaa tacatccctc
     4441 tggtacacca atgctaacaa tagcgacagc gacgacgttg gagccagcgc agggatagaa
     4501 ataccgttta gtttataagg ctgaatgctg aaaacagggg agagagggtg gtagccctgc
     4561 aggacgcagt cagcttttat ctctccacaa gccggcaggg aagtaacggc tatgacagct
     4621 gctcaggaat tggcaaattt tgatttactg atgatgtgac attatgaaga aaaaacttgt
     4681 tagattttcg gcattagcat tggcaattgg gtttttatcg ggttgtacga ttatccctgg
     4741 tcaaggatta aacagtctgc gtaagaacgt agtcgaactt ccggatagcg actacgacct
     4801 ggataaactc gttaacgttt atccgatgac acctggattg gttgatcaat tacgacccga
     4861 agcagtatta gcaaaatcaa atcccgattt agatagactg cttggcaact atgagtatcg
     4921 aattggtgta ggcgatgtgt taatggtgac tgtttgggac catcctgaat tgactacgcc
     4981 agctgggcag taccggagtg caagtgatac aggcaactgg gtgaactcag atggcacgat
     5041 attttacccg tatataggta agattaaagt tgcaggtaaa actttatcac aagtacgtca
     5101 ggaaatcgca agtcgtctaa ctacttacat agaaagccca caagtcgacg taagcattgc
     5161 agcgttccgt tcacaaaagg tatacgtaac gggggaagtt gcaaagtctg gacaacaacc
     5221 tataacaaat attcccctta cgataatgga tgcaattaat gccgctggcg gtttagcacc
     5281 ggaggcggat tggcggaatg tagtattaac acataatgga aaagacataa aaatttcatt
     5341 atatgcttta atgcaaaaag gcgacctaac acagaaccat ttattgtatc cgggtgatat
     5401 actttttatt cctcgaaacg atgatttaaa agtatttgtc atgggggaag ttggtaagca
     5461 aacaacactc aaaatggatc gcagtggtat gacccttatg gaggctgtcg gaagggctga
     5521 gggaatatca caggcgatga gcgatgcaac tgggatattt gttatacgtc agttaaaaaa
     5581 taataatggc ggtaaaatag ctaatatcta tcaactcaat gcgcaagacg catcagccat
     5641 ggtattaggc actgaatttc aattagaacc ttatgatata gtttatgtta ctgcagcgcc
     5701 tattgtaagg tggaatcgcg ttatatcaca acttgttcca accataacag gtgttcatga
     5761 tatgactgaa actgtccgtt atattaaaaa ttggaattga ttatgtttga ctcgattctt
     5821 gttgtttgta ctggtaatat ttgtcgctct ccaatgggag agcgatattt acaaagtttg
     5881 ctacctaaca aaaaaataga ttcggcagga actggagcct tggtagggca tgaagctgat
     5941 cctactgctt ctcgtatagc acaaaattat ggcatatcct tatcaaatca ttgtgcaaaa
     6001 caattcacaa gtactttagg aagaaaatac gatctcatat tagctatgga gaaggaacac
     6061 atagagaaaa taagtcaaat tgcacctgaa gttagaggga aaacgatgct gtttggccat
     6121 tgggcagaat ataaggatat acctgacccg tatcgcaaaa gtgaagaggt atttactttg
     6181 atttttgaat taattaaaca gtccggtgat atctgggcca aaaaactgag cgtataacaa
     6241 ccggggttta atacatgtca tcacttaaaa ataagccaga aaacaaagat gcagatgaaa
     6301 tagatttgag tcgtttatat ggtgaactta tcgatcatcg taaactaatt atatcagtaa
     6361 ctgctttttt tactttgatt gctttagtct attcattatt ttcaactccg atctatcaag
     6421 ctgattctct aatccaagtt gaacaaaagc aggcgaatgc catattgagc aatttgagcc
     6481 aaatgcttcc ggatagtcag ccacaatctg cacctgagat cactcttctc caatcaagaa
     6541 tgattttagg gaaaacggtt gacgatttga atctgcaagc caaaattaaa caaaattatt
     6601 ttccgatttt ggggagagga ttttcacgtc tctcaggaga taaaccaggt attataaatg
     6661 tatcaagatt atatttacct aaaaccgatg atgacatacc agaattaacg ctaacagtta
     6721 ttgacgcaaa taaattcact attcagaccg attcatttga agctgaagta aaagttggag
     6781 agttatttga gaaaaataac atttcgataa aggtagatga aattcaagca aagccaggta
     6841 cttcatttac ggttgaatat ctaagcaagc taaaagctat taatgattta agggatgtgt
     6901 tgacagtaag cgatcaaggt aaagatactg gaatgcttac attgtcattg acaggagatg
     6961 atcctgtaca gattaggaaa atattagata gcatcagtaa taattatttg atgcaaaata
     7021 ttgacagaca agcagctcaa gatgctaaaa gcctagagtt tttaaatagg cagttaccac
     7081 aagtacgtca tgatttagat atttcagaag ataaattaaa taaatacagg caacagaaag
     7141 attctgtaga tttatcgctt gaagcaaaag cagttttgga tcaaatagtc aatgttgata
     7201 atcagcttaa tgaactaacc atacgtgaat cagaggtatc acaacatttc acgaaagagc
     7261 atcctactta taaggctctt atggagaaaa gagtgacgct tcttgaagag aaagccaagc
     7321 tcaataaaag agtatcggcc atgccagaaa cacaacaaga ggtgttacga ctaagtcgtg
     7381 atgttgattc tggtcgcgct gtgtatatgc agttattaaa tcgtcaacaa gaattgaata
     7441 ttgctaagtc aagtgctatt ggaaatgtaa gagttattga tgaagctgta acacaaccaa
     7501 gaccagtagc acctaaaaaa atattaatag ttataggtgg tattatattt ggcctgattg
     7561 tttcagttgc aattattgct ttgagagttt tcttgcgccg tggaattgaa tcgccagagc
     7621 aattggaggt actaggcatt aatgtatatg ctagtattcc agtttctgag acatttgcaa
     7681 agaatatcac aaagggttta aaatctaata agaaaaagag tctggagtat gacgagtttc
     7741 tggccatcca aaatccagct gacctcgcaa ttgaagccat caggggatta agaacaagtt
     7801 tacattttgc tatgatggaa gcgaggaata atatacttat gatttcaggg gctagcccaa
     7861 atgcaggcaa gactttcgta agttcaaatt tagcagcaat tatttctcaa acaggtaaaa
     7921 aagttctctt ccttgatgct gacttaagaa aaggttatac gcataagtta ttcaatgtat
     7981 ctaacgaaaa cggtctttcg gattatttag caggaaaagt agatataaaa aattgcgtga
     8041 aacaaattaa aacagctggc tttgatttca tatccagagg gatggtgccg cccaacccag
     8101 cagaattatt aatgcattca agattccaga atcttctttc atgggcgagt gacaattatg
     8161 atttagtaat tgtagatact ccgccgattt tggcagtaac agatgcagct attattggca
     8221 attatgcagg tactactctt ttagtcgcaa gatttgaaca aaatacagta aaagaaatag
     8281 aagtcagtgc aaagcgcttt gaacagagcg gagtaatgat taaaggctgt atattaaatg
     8341 gagtggtaaa gaaagcaagc agttattatg ggtatggtta tagccattat ggctattctt
     8401 actccaataa agagtaaagc acaaaccatc agtacagtat tcacaaattg tactgatggt
     8461 tgattctaac tttaatgaaa gtgatttgtt tatgagaata atgattttaa actctcttta
     8521 ttatccttat agagtcggag gtgcagaaat atcagttcaa ttattagctg aacaattagt
     8581 taaattagag aatgaagtaa aggtaataac acttcatgat aaaaaagaaa taaaaacaga
     8641 ttttgtcaat ggagttgagg tcacttatct tcctcttaag aatatttatt ggggtttccc
     8701 caacacaaca acatcaaaat ttaaaaaggc catctggcat ttcattgatt gttataattt
     8761 tgaaatgaaa aaaatggtga gcgtacagat cgcgcaattt aaaccagata tagttcacac
     8821 aaataatata tgtgggtttt cggtatcggc atgggatgct gtaaaaaaag cgaaggttaa
     8881 gcttgtacat acttctcgtg attattactt attccatccg aacagtacac tgtttaaaag
     8941 tggtaaagta atgtcaccaa gttctttatc agttctattt tggagttggt ttaaaaaaat
     9001 aaaaagtaac aaagtagata attatattgg cattagtaaa tatattacta atttacataa
     9061 ggattgtggc ttttttaaaa aagccacttc ggattttata tataactcag ttactccgta
     9121 tgtgccgaaa aaaaatgaga gcgataaaat aaggatcggt tttattggtc gattgtcggt
     9181 tgaaaaaggg tttgatgtat attgtaaagt agctagacaa tataaagacg taaatgaact
     9241 gaagttttat gccgcaggga attttcaggc tggaaatgat agcaatttac ttaaaaaaga
     9301 tgccattgaa aactccgttg aggttttggg ttatatggat ttggcggaat tcttggaact
     9361 ggttgacatt gttattctac cgttgaagtg gaatgaacct tttggccgta cagttgttga
     9421 atgtgcattg gcaggaaagt atgttatcac aacttctatg ggagcaatga ttgaattggc
     9481 tcagataatg ccaaatgttg ccatcataaa tgatatcgag catgaattag atatctttca
     9541 aagatataca cttcatcaag atttagcaga tgatgtcaaa cagctatttg atccagataa
     9601 tattgccaaa caatatataa atcattataa aaaatagcct aaatgagagt ttaatatgac
     9661 attgcaatca tttgaatcaa gattaataaa cttctcatta cttttatttt tactatttga
     9721 gtttttcgca ggaccattac gctggttgtt ccatttgtta ggtgctgagc ttttattttc
     9781 tatacctaaa ttgttaattt taattactat cctagtttct gttttaaata ttatttacaa
     9841 aagaaaaata acaaaaaacg gattaatagc ctcaatttcc atcatataca tattattagt
     9901 gagtatagta catgttgaac ttgcagcagg ttttgttgct ttttggggaa ttatacccat
     9961 attccttggg tatcactcag ctaggattat atttgaaagt gtacaaaata ataaaactaa
    10021 taatataatt tattttgttt tttatgtttc atgtattggt gtattttgta atattatatt
    10081 taattatcct tggtatgatg tttcatatga gattgcaggc atggatgtgt catctgctca
    10141 aatgggaacg actggtggat atacaagata tgcgggtttt tttaaaagtt cgcttcaagc
    10201 ttcatcaaat attttaatat tgttggttta tattgttgca tcaacaaaaa ataaattctt
    10261 tattcttgtg tgttttattc ttagtttgtt ggtgtcaata ataacaatat caaagacaac
    10321 atttgcattg catttgatat tgctgtttta cgtatttatg aaaattttac ctgttaaact
    10381 tttatggaga agtactctta tatttgcaat tgttgtcacg tttttcacca ttatgtccac
    10441 gaactattcc tttgaaatga ataatgatcc tgcaactact atgttattag gatctttaaa
    10501 tgcacgttta accactacgt ggccagatgg tgtcgagtca atattaaaat ttggcagctt
    10561 aacgttcggt gctggactag gtacaatcgg ggttggctca aaactgggat cagggactta
    10621 caatcctggt gatagcatgt atctttatat tattgctaca ggaggatata tattaggtat
    10681 atatttattg ggatggttat attatcagtc taatatttta aataattctg ctatttctcg
    10741 attcctttct atgactctta ttatactttg tttattcgga atttcgatga ccacgccaga
    10801 gtatcctctt atggggtttg cattaggtgt aatatttaac agcagagcaa gtaatttaca
    10861 atataaagaa gctgagtgat tatgaaaaaa atagttaatt ttgattctcg ttggattggt
    10921 gaacatggta tagggcgttt tgcgaaggag attcaagatg gtatacctgc tttaaataga
    10981 ataaaagtag ctattaaacc aacaagccct ttcgatgttt tttttgttac tctatatctt
    11041 atgtttaata gaggttatta tttcacacca gggtataatg ctcctttttt ccatcttaat
    11101 cgtacagcca taacaattca tgatcttaat cacatagaca ttgattttaa ctcaagtgtt
    11161 cttaaacggt tgtattacaa tttagtatta aaaagagcat gccggaaagc acgagttata
    11221 ttaaccgttt cagagttttc aaagaaacga atatgtgaat gggctaaaat taatcaagat
    11281 aaagtaaagg tagtagggaa tggtgtttca aaagaattta atttagaggt taacgggctt
    11341 aaagaaaatt atattttaag tgttggtaat cggaagaagc ataaaaatga aattgcagtg
    11401 ttgaatgctt tctgttctgc aaatattcca gaggctgtca tgctttattt tactggcgag
    11461 agaagtgagg aactattaaa tcatgcaaaa aaattaaata tatcgaatcg aataaaattc
    11521 atggggcgag ttgataatga aacattagct aaattatata aaggagcaaa tatgcttctt
    11581 ttcccatctc tgtatgaagg ttttggttta cccgttatag aagcaatggc ttgtggaact
    11641 ccggtaatta cctctaatgt cacatcttta cctgagattg ctggtgatgc tgcattatta
    11701 gttgatccta taaatcacgg agatataagc ttggcaattg aaaaaattta ttatgacata
    11761 gcgttgaggc aaaaattagt tgaggaagga ttaaaacaag ttaagaaatt tacttggcaa
    11821 aaaaccataa ataatgtcaa gaacgaacta gagacagcat ttactattaa attataggta
    11881 ttacaatgct aaaaaatact atgaataagt tattattttc agtatctata attctcagtt
    11941 taaactctcc tgttgcttca tcgttggaaa ttggaattgg tactcatttt caatcatata
    12001 gttcaactcc cgaaacatat atttcattaa tcaaagaatt aggttttaca tcttttcgcg
    12061 atgattatcc atggtcgaaa acagaaggca gtgaaggagt ttattctgtt tctaaatttt
    12121 tgaaaaaaac agattatgct ttacttaatg ctgacaggga tggtttgaat ccactcgtta
    12181 ttcttgatta tggtaataag ttgtataata acggaggtta tcctacaact gaacgtgaca
    12241 ttcaagcatt tgctaattat gcgggatggg tatcgcatcg ttataaaggg aaagttaaat
    12301 attatgagat atggaatgaa tggacgatag ctactggcat ggttaaatac cgaaatcaag
    12361 ttccttcggc caatgtctat tataatttag taaaaaaaac tagtgaagta ataaaaagga
    12421 atgacccgaa tgccatcatt cttgcgggtt ctataaatcc tctcgattta agagcaagat
    12481 atattgatgt taatgattgg aaatggtttg agcaactagt aaacttagga attttgaatt
    12541 atattgatgg tgtatcattg cacacatatt catttatgaa tggtaatccg ctgttacgta
    12601 caccacaggg taatcttaat cgtatagatg cattccatac ttactttact aaaaaaacag
    12661 ggaggagcat agatgtatat ataactgaag caggggtgac gaattatgat gggcctggag
    12721 gaatggattt aatacagtct gcaaatttta ttaaagaata tactagccta gtcaagaaac
    12781 gatcttatat taaggggctt tggtggtacg atcttattga tgatggaaca gatattaaaa
    12841 acaaagagca taattttggt ttcttcaaaa ataatttgga accaaaagcc tcagctgaat
    12901 ttatgatggc aaagtaataa ggcacgatta aatgtattat ataaaatgca ttttttatat
    12961 ttcttaatgc cgcatcacta taacgagaac aaaaaataat gagatcaaaa aaaatgactt
    13021 cattttgttg ttttgcataa atttttgtaa caacactcat tgttaaagaa aggttattga
    13081 ctcacaaagt ttttttagtt tatgaatgta acatgtttat attgtaatag attgagttat
    13141 tgacttttta gaataaaaat tgaatatttt cacaattaag gattaattca tgcataattt
    13201 gaatattgga attgttgctg actggttggt cacgtacgca ggttcagaaa aagtaattaa
    13261 agaattttta gaagtgtttc ctgaaagtga attgtattca attgttgatt ttttatccga
    13321 tgaggataga gttaatttca agggaaagaa agcaactact agctttatac aaaaattccc
    13381 tttttctaaa gttaaatacc aaaagtatct accattcatg ccattagcta tagagcaact
    13441 tgatgtttca aaacatgata ttatattatc tagcagtcat gctgttgcaa aaggtatcat
    13501 aacaggtcct gaccaattac atatatctta catacattcg ccaattagat atgcctggga
    13561 tttacaacac caatatatta aagaggcggg tttggataaa ggtatgaaag gaatggttgc
    13621 tcgatggtta ttacataaaa tacgtttatg ggattgccgt acatcaaatg gagtagatca
    13681 tttcattgct aattctgagt ttatatctag aagaatcaga aaagtatatg gacgtgaatc
    13741 aaaagtaatt tatccaccgg ttgatgttaa tagattcggg ttatgtgaaa acaaggatga
    13801 ttattatttt acagcatcca gaatggttcc ttataaaaga atggatttga tagttgaggc
    13861 gttctcacaa atgcctgata aaaagcttgt agtaataggt gatggttcag agatgtcaaa
    13921 gattaaggca aaagcttcaa gtaatattga actattagga tatcaaccaa attcagtgat
    13981 gcaagagtat atgcaaaaag caaaagggtt cgtatttgca gctgaagaag atttcggcat
    14041 tacgccagtt gaagcgcaag cgtgtggaac tcctgtaata gcttttggca agggtggagc
    14101 attggaaaca gttcgtccat gcggggttaa taaagctact ggtgtatttt tttataaaca
    14161 agaaattaag tctcttgtaa atgctgttca ggaatttgaa aaaaatatcg atgtatttaa
    14221 tccacaacat tgcagagaaa atgcaattcg cttttctgag gaaaggttta agcaagaaat
    14281 aacccagttc gttgatcaaa aatggtccgc ctttaaaaat aacaaacaaa ttatatacta
    14341 gttactacta tcattacttc tgttattatt tgtttttata caaaaagagt tgataagtaa
    14401 tattattttt atattacttg ggaaataatt tactcggtga ggatatatgt ctcgtctagc
    14461 tcgaaatttt tggacaagta ttttattagc gatatctgat ttcactggtt ttacggttgc
    14521 tattgcattc gcaatctttt ttgtgaaatc ttttatgaat gatggcggac aaattattgc
    14581 taatagcaat attaatgatt gggttattct ccacacttgt ttaggcatat gttgtgtggc
    14641 gtggtattcc attcgcctaa ggcattattt ttacaggaag acattctggt tcgaattaaa
    14701 agaaatatta cgcaccttag ttatttttgc aataattgaa attgcagtgt tatcatttgc
    14761 ttattgggat ttctcacgtt atattttggc agttacatgg attttcgtat tattttttgt
    14821 ccctacattt cgtatgctca ctaaaaagtg tttgaatttt tttggattat ggaagcgtga
    14881 aacaataata attggtgatg gaaataacgc agtagaagcg tggaaagcaa taaatagtga
    14941 atcaaactta ggttttaatg taactagttt tgtttcaagc acatcaaaag atcacctcaa
    15001 aaatcacatt aacgatattc ctgtaatatc tttaaatcca aaagaagtaa caaagcattt
    15061 tgataaaaga acacaattca ttgtcgcttt agaaactagt gaaagttcga tacgtaatga
    15121 ttggcttaga gaatttctta ttaatggttt tagatatgta tcagttattc ctacgttgcg
    15181 tggtgtgcca ttggatagta ctgatatgtc ttttattttt agccatgaag ttatgatttt
    15241 ccgtgtacaa cagaatttag cgaaattatc atcgcgtatt cttaaacgtt tgtttgatat
    15301 tataggttca ctcaccataa ttcttgttag ttcaccatta ttaatttaca ttgctttgaa
    15361 agtaaaaaaa gatcatgggc ctgccattta tggtcacgag cgtataggta atggcggaag
    15421 gccttttaaa tgtctaaaat ttagatctat ggtagtcaat tctaaagaag tgcttgagca
    15481 acttttaaat actgatcctg ctgcacgtaa agaatgggat gcgactttta agttaaaaga
    15541 tgatcctcga ataacggata ttggtaaatt tttacgcaaa actagtttag atgagctacc
    15601 ccaacttttt aatgtactta aaggtgaaat gagtttggtt ggacctcgac caattataac
    15661 cgcagagctt gaacgttatt ctgacgaagt tgactattac cttcttagta aaccaggtat
    15721 gactggtctt tggcaagtta gtggaagaag cgatgttgac tatgaaaccc gtgtctattt
    15781 ggatgcatgg tatgttaaaa actggtctat gtggaatgat atagctatct tatttaaaac
    15841 tataagtgtt gttttaagaa aagatggagc ctattaattg ttttttgaat atttgatcta
    15901 atttaattgt cgagggaata atgaaaatat tactagttgg aaatcatact tgcggtaatc
    15961 gaggtgatgg tgcaattctc agaggattag tggattctat aaaacagatc aatccagatg
    16021 tagaagttga tattttgagt cgttatgcaa ggagttcagc ctttttacta ggaactgcta
    16081 ttaagcaaga tgtcctatat tcatcaagaa tgaataaaaa tggtgggctt gttaaaaaag
    16141 ttatttggaa gatcaagaat agtattcttc ctgatatatt agtttcgcat gcaaaaggca
    16201 aaggtttttt aaagtatttt cctttgccaa ataatgttgt tgaatttatt aaagatcttg
    16261 aaaaatatga tgctgtcatt caggtcggtg gttctttctt tgtcgattta tatggcactg
    16321 gacagttcga acatatctta tgttcaaata tagcgggtaa accaatatat ttagttgggc
    16381 acagtgttgg tccttttgag aatcctaaat tccagcatat cgcaaaatat tgttttacta
    16441 aagcagagaa gataatacta cgtgaagatg ttagtttatc tttgatggaa aaggataact
    16501 tcaacttaaa caatgtaaca ttgggtgttg atacggcttt tttggtggat acagaaaaag
    16561 atgttaatga ttatgctgtt tctcattgga aaaagataat taaagaacag aaaacggtag
    16621 ctttaacagt taggaaacta gcacctttcg ataaacgttt aggtgtttct caagatgagt
    16681 atgaggcttc aatcgcccgt attgttgatt atttgaacca attaggttat caggttataa
    16741 tattttcaac atgcactggc attgaaagtt atcatagtga tgaccgaatg gtagcccttt
    16801 ctgttaaaaa taaagttcat gatagtcaat gttgccatgt cgtaatggat gaattcaatg
    16861 attatcaatt agggatttta ttatctaatt gcgtctttac aataggtaca agattgcatt
    16921 ctgctatcat ttctatcaat tttggaacac ctgcaatagc aattaattat gagcataaat
    16981 cgttgggtgt tatgcgtgga ttaaaaatgg atgtgctatc agctgatgtt agcgatgtca
    17041 ttgatgggac attgattaat aaaatagaag atttaattgc taatatggct gatattgaaa
    17101 tttccttaaa aaataactta caagatgcaa aaataattgg ccgcacaatg attgaaaaca
    17161 ttctttctga gattgataga taatgaaaat actttttttt tgtattcgat tcccactcgc
    17221 ttctgaaact tttgttttaa atcaagttat ttcctttatt aaaaagggtt atgatgtaaa
    17281 agtattgtct ttatatccgg gagatactga aaaagtacat ggcgattttg aaaaatacaa
    17341 cataggtgct cttatagaaa atatttttga cgctgatgaa ataccgggta ataaattatc
    17401 ccttatcttc tcgagagcaa aaattgtttt aaaatcaagt tcatttagta ttattaaagc
    17461 attcaacttt gagagattta aatttttatc ctactcatta ttattacctg cgatttttgc
    17521 aaagttaagg aataataaaa tttcagcgga tgttataatt gctcactttg gtcattgtgg
    17581 tgtgcttgct aacgcaatca ggaatatcgg gttaattaat ggtaagcttt tgactgtatt
    17641 ccatgggtat gatatttcta caattagcct tcttaaaaaa tataagattt tatataaaaa
    17701 tttattttct cagggtgaat acttcttacc tataagtaac ttatggcgag ataagttaat
    17761 cagtatgggg tgtgataaag ataaaatatc ggttataaga atgggaatta aaatagacga
    17821 atttaaatat gaatttcatg cacgtgatca atcaacttta aacattattt ccgtctgcag
    17881 attaactgaa aaaaaagggc tggtatatgc tattgatgct tgtaatgcgc ttaagaataa
    17941 aggatgcaaa tttaaatata aaataattgg ttatggagaa ttagagaatg tgctagccga
    18001 aaaaattaaa gcactaggac ttcaggatta tgtctatctt ttaggatttc agccacaatc
    18061 agtagtaaaa acagctcttg ctgagagcaa tgtctttttg cttccatccg taactgctag
    18121 taatggtgat atggaaggaa tacctgttgc acttatggaa gcaatggcgt caggcttacc
    18181 agttatttcc acttatcata gtggtatacc ggagttaatt gatgatcata agaatggtta
    18241 tctttgccca gagcgtaatt ctgaagctat agcaaaaatt ttatatgaaa tatatgaagg
    18301 aaaagataat ctatcattaa ttgcttctga agcgcgtgat aagatttatt ctcagtttaa
    18361 cgaggaggtt gagttcaaca aaatcgtcac tttgctggag agcattaaat gagtggcatt
    18421 aaaaaacaag caatttggtt attaggatcc aatacaattt ctgccattct tcagattcta
    18481 caaattagtt tgctagctca ccatcttaaa ctaagtgagt taggagtact agctatagtc
    18541 aatatggtat tgatggttgc gatgatcttg caggatatgg gaatgagcag ttatatagtt
    18601 catatgcaag aaatgacaag aagagatcag agtactattt attggatcaa cctgttactt
    18661 agtttcctga cagggtgcct tgttttcgtt gcgtcttggc ctatagcatc tttttacaat
    18721 atgcctgact taactttttt agtaatgttg gcaagcttta attttctttt tctaggatct
    18781 ctatcgcaat atcaatcgca ctacataaaa gcaaaaaaag ttatactttt ggctaaaata
    18841 gaaatcattt ctaaaattat ttctttttta ttcgttttgt tctcaatttt aaagatggat
    18901 ctgagaactg aggctgtgat ttatggtctg attattaatt cttttgctcg tcttttttta
    18961 atgtcattat taggtgataa atcttggcga cctacttttg agtttaattc tgctatatgt
    19021 aagccggttt ttaaatatgg gatctttcaa ttaggctcac agattctaaa tcaatttcgc
    19081 acacaattag atgttattgt aattggtaaa atgctaggtg cggattcact tgggttatat
    19141 tctttagcta aagatctcat catgcaacct ctaaagctga ttagtcccgt aataaataga
    19201 ttggctttgc ccagatttgc agaggttcaa aatcaatctg ataaacttgg tggtgcatat
    19261 ctgcgtggaa catctgtaat tctgttgttt agcatgataa cttttttctc tatttatttg
    19321 ttggggccag ttataatcaa aattttatat ggttcaagtc gcatgggggt ttttaatatt
    19381 ctaccatata tgcttttgtt tggtgtttta agacctatgg gtgggttaac aggcgctgtg
    19441 gctcaagcaa atggcaagac taacattgag ttcagatgga atgttatagc aacttcgatt
    19501 gttttgggtg ttactactac tgtttttttt attcctcagt tatggtatgt ttcgttaagt
    19561 ctttcacttt ctcagttatt gattagtttt tttgtttttc cttgttttat aaaacctatt
    19621 gtagatgtga gttttaaatc atatttatat aaatggtttc cacaagcttt atgctttata
    19681 tgcttgattt atattgtcaa gttttttgat ctcgtgcttt accccttttg gtgaatttca
    19741 gaccaaaaat tttaaaagca ctaaacatct aaagatgtcc tttgccatac gttgacctta
    19801 cgttaatatt atatgtactt taccctgcga gaatttcgca tagagcacac ctgacaggag
    19861 tatgtaatgt ccaagcaaca gatcggggtt gtcggtatgg ctgtgatggg gcgtaacctt
    19921 gcgctgaaca tcgaaagccg tggttatacc gtctccgttt ttaaccgctc ccgtgaaaag
    19981 accgaagaag tgattgccga aaatccaggc aagaagctgg ttccttacta cacagtacaa
    20041 gagtttgttg aatccctcga aacaccacgt cgtatcctgt tgatggtgaa ggctggagct
    20101 ggcaccgaca gcgccatcga ttccctgaag ccttacctcg acaaaggcga catcatcatt
    20161 gatggcggca acaccttctt ccaggacacc atccgtcgta accgtgagct gtctgccgaa
    20221 ggttttaact ttatcggtac cggtgtttcc ggtggtgagg agggggctct gaaagggcct
    20281 tccatcatgc ctggtgggca gaaagaagcc tatgagctgg ttgctccgat tctgaagcag
    20341 attgctgcag ttgctgaaga cggtgagcca tgtgtaacct atatcggtgc tgacggtgct
    20401 ggccattatg tgaagatggt tcataacggc atcgagtatg gtgacatgca gctgattgct
    20461 gaagcttatg cgctgttgaa aggcggtctg gcactttcca acgaagagct ggcgcaaacc
    20521 ttcaccgaat ggaacgaagg tgagctaagc agctacctga tcgacattac caaagatatc
    20581 ttcaccaaga aagatgaaga aggtaagtac ctcgttgatg tcattcttga tgaagcagca
    20641 aacaaaggta ccggtaagtg gaccagccag agctcactgg atctcggcga acctctgtct
    20701 ctgataaccg agtccgtatt tgctcgctat atttcttcgc ttaaagacca gcgtgtagcc
    20761 gcgtcgaaag tgctgagtgg tccgcaggcc cagccggccg gtgataaagc tgcatttatc
    20821 gaaaaagtgc gtcgcgcctt gtacctcggt aaaatcgtct cctatgctca gggcttctcc
    20881 cagctgcgtg ctgcttctga tgaatacaac tgggatctta actacggcga gatcgctaag
    20941 attttccgcg ctggctgcat cattcgtgcg cagttcctgc agaagatcac tgatgcttat
    21001 gcgcaaaacg ctggcattgc taacctcctg ctggcgccgt acttcaaaca gatcgctgat
    21061 gactatcagc aggcgctgcg tgatgtcgtg gcgtatgccg tacagaatgg tattccggta
    21121 ccgacgttct ctgccgcaat tgcctactac gacagctacc gttccgcagt tctgcccgct
    21181 aacctgattc aggctcagcg tgattacttt ggtgcgcaca cctataagcg cactgataaa
    21241 gaaggtgtgt tccataccga gtggttggaa taatctttat attccacagt caggccaatt
    21301 ggcctgactg ttagctattg ttagttattc tacaataatc tgatcaaagt tatcttattt
    21361 gcacgtcttc gtcatttatc cagctctaat aaagcaaatt cgtatctttt aagaatttgc
    21421 catatttata cttttgtata cctataataa gctacttctg gcctcagaat atatctgggt
    21481 gttaaataac agggttttaa ttaaaggaaa ttaatatgtt acttcctgtg ataatggctg
    21541 gcggtaccgg cagtcgtctc tggccgatgt ctcgcgagct ttacccgaaa cagttcctcc
    21601 gcctgttcgg gcagaactcc atgctgcagg aaaccatcac ccgactctcg ggccttgaaa
    21661 tccatgaacc gatggtcatc tgtaacgaag agcaccgctt cctggtggcc gaacagctgc
    21721 gccagctcaa caagctgtcg aacaacatta ttcttgagcc ggtcgggcgc aacaccgccc
    21781 cggccatcgc cctggcggcc cttcaggcca cccgtcacgg cgatgacccg ctgatgctgg
    21841 tcctcgccgc cgaccatatc atcaataacc agccggtctt ccacgacgcc atccgcgtcg
    21901 ccgagcagta tgccgatgaa ggccatctgg tcaccttcgg tatcgtgccg aacgccccgg
    21961 aaaccggcta cggctacatc cagcgcggcg tggccctcac cgacagcgcc cacaccccgt
    22021 accaggtggc ccgcttcgtg gagaagccgg accgcgagcg tgccgaggcc tacctcgcct
    22081 ccggggagta ctactggaac agcggcatgt ttatgttccg cgccaaaaaa tacctctccg
    22141 agctggccaa attccgcccg gatatcctcg aagcctgcca ggccgcggtc aatgccgccg
    22201 ataacggcag cgacttcatc agcattccgc atgacatttt ctgcgagtgc ccggacgagt
    22261 ccgtggacta cgcggtgatg gagaaaaccg ccgacgcggt ggtggttggt ctcgatgccg
    22321 actggagcga tgtcggctcc tggtccgccc tgtgggaggt cagcccgaaa gatgagcagg
    22381 gtaacgtcct cagcggcgac gcgtgggtgc acaacagcga aaactgctac atcaacagcg
    22441 acgagaagct ggtggcggcc atcggcgtgg agaacctggt gattgtcagc accaaggacg
    22501 ccgtgctggt gatgaaccgc gagcgttccc aggacgtgaa gaaggcggtc gagttcctca
    22561 agcagaacca gcgcagcgag tacaagcgcc accgcgagat ttaccgtccc tggggccgct
    22621 gcgacgtggt ggtccagacc ccgcgcttca acgtcaaccg catcaccgtg aaaccgggcg
    22681 gcgccttctc gatgcagatg caccaccacc gcgccgagca ctgggtcatt ctcgccggca
    22741 ccggccaggt gaccgtcaac ggcaagcagt tcctgctgac cgagaaccag tccaccttta
    22801 ttccgattgg cgccgagcac agcctggaaa acccgggccg cattccgctg gaagtgctgg
    22861 agatccagtc ggggtcgtac ctcggcgagg acgacattat tcgtattaaa gaccagtatg
    22921 gtcgttgcta attttttcgg gacaaaacgc agaatgacac agttaacatg ctttaaggct
    22981 tatgacatcc gtggtgaact gggtgaggag ctgaacgagg acatcgccta ccgtatcggc
    23041 cgcgcctacg gcgaatttct gaaacccggg aagatagtgg tggggggcga tgtgcgcctc
    23101 accagcgagt cgctgaagct ggcgctggcc cgcgggctga tggacgccgg caccgacgtg
    23161 ctggatatcg gcctgagcgg cacggaagag atttacttcg ccactttcca cctcggggtg
    23221 gacggcggta tcgaggtgac ggcgagccac aacccgatga actacaacgg catgaagctg
    23281 gtgcgcgaga acgcgaagcc catcagcggc gacaccgggc tgcgggatat ccagcgcctg
    23341 gcggaggaga atcagttccc gccggtggac ccggcgcgtc gcgggaccct gcgccagatt
    23401 tcggtgctga aggagtacgt cgaccacctg atgggctacg tggacctggc gaacttcacc
    23461 cgtccgctga agctggtggt gaactccggc aacggggcgg cggggcacgt gattgatgaa
    23521 gtggagaaac gcttcgcggc ggccggggcg ccggtgacct ttatcaaggt gcatcaccag
    23581 ccggacggcc atttcccgaa cggtatcccg aacccgctgc tgccggagtg ccgccaggac
    23641 accgccgacg cggtgcgtgc gcatcaggcg gacatgggta tcgcctttga cggcgacttc
    23701 gaccgctgct tcctgttcga tgacgaggcg tcgtttatcg aggggtacta cattgtcggc
    23761 ctgctggcgg aggcgttcct gcagaagcag ccgggggcga aaatcattca cgacccgcgt
    23821 ctgacgtgga acacggtgga catcgtgacc cgcagcggcg gccagccggt gatgtcgaag
    23881 accgggcatg cgttcatcaa ggagcggatg cgccaggaag acgccatcta cggcggggag
    23941 atgagcgcgc accattactt ccgcgacttc gcctactgcg acagcgggat gatcccgtgg
    24001 ctgctggtgg cggagctgct gtgcctgaag aacagttcgc tgaaatcgct ggtggcggac
    24061 cgccaggcgg cgttcccggc gtcgggggag atcaaccgca agctggggaa tgcggcagag
    24121 gcgatagcgc gcatccgggc gcagtatgag ccggcggccg cacacatcga cacaacggac
    24181 ggtatcagta ttgaataccc tgagtggcgc tttaacctgc gcacgtccaa taccgagccg
    24241 gtggtgcgtc tgaacgttga gtccagagcg gatactgcgt taatgaatgc aaaaaccgaa
    24301 gagattttag ctcttctcaa gtaatgcatt atccataatg gaagccatag ggtcagattt
    24361 taatcgtatt attgacctta tggcttattc ttgacatccc actggtcaaa gcgtaaaacc
    24421 gcccacagca atatttaaat tcgtggctat ccgccattac ccagttaact gattaaagtg
    24481 taatcgaatg aaaattacta tttccggtac aggttatgtt ggtttatcga acggtgtcct
    24541 gattgcgcaa aaccacgaag tggtggccct ggatatcgta caggccaaag tggatatgct
    24601 taaccagaag atctctccga ttgtcgataa agagattcag gaatatctgg cagaaaaacc
    24661 gttaaatttc cgtgccacca cggataagca cgacgcatac cgtaatgccg actacgtgat
    24721 cattgccacg ccgaccgact acgatcccaa aaccaactac ttcaacacct ctacggtgga
    24781 agcggttatt cgcgatgtca cagagatcaa ccc
//
