LOCUS       AB924562               25919 bp    DNA     linear   BCT 28-OCT-2015
DEFINITION  Klebsiella sp. 1680/49 DNA, capsular polysaccharide synthesis gene
            cluster, serotype: K24.
ACCESSION   AB924562
VERSION     AB924562.1
KEYWORDS    .
SOURCE      Klebsiella sp. 1680/49
  ORGANISM  Klebsiella sp. 1680/49
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella.
REFERENCE   1
  AUTHORS   Pan,Y.J., Lin,T.L., Chen,C.T., Chen,Y.Y., Hsieh,P.F., Hsu,C.R.,
            Wu,M.C. and Wang,J.T.
  TITLE     Genetic analysis of capsular polysaccharide synthesis gene clusters
            in 79 capsular types of Klebsiella spp
  JOURNAL   Sci Rep 5, 15573 (2015)
   PUBMED   26493302
  REMARK    DOI:10.1038/srep15573
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25919)
  AUTHORS   Pan,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2014) Contact:Yi-Jiun Pan National Taiwan
            University College of Medicine, Department of Microbiology; 1, Sec
            1, Jen-Ai Rd., Taipei 100, Taiwan
FEATURES             Location/Qualifiers
     source          1..25919
                     /organism="Klebsiella sp. 1680/49"
                     /mol_type="genomic DNA"
                     /strain="1680/49"
                     /serotype="K24"
                     /db_xref="taxon:1497802"
     gene            1693..2595
                     /gene="galU"
     CDS             1693..2595
                     /gene="galU"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase
                     subunit"
                     /protein_id="BAT23443.1"
                     /translation="MKMNMANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVT
                     IMNVRQAQPLGLGHSILCARPVVGDNPFVVVLPDIILDGGTADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGR
                     YVLSADIWAELERTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQA
                     FVTYGMRNLKEGAKFRESIKKLLA"
     gene            2988..3617
                     /gene="cpsACP"
     CDS             2988..3617
                     /gene="cpsACP"
                     /note="orf2"
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase homologue"
                     /protein_id="BAT23444.1"
                     /translation="MNWQLISFFGDSTVLLPSAAALFIVLMLRKTSRLLAWQWSLLFG
                     ITGAIVCASKLAFMGWGLGIRELDYTGFSGHSALSAAFWPIFLWLLSARFSAGLQKAA
                     VATGYILAAVVGYSRLVIHAHSVSEVIAGLLLGAAGSALFLVLQKRTPDPESVNISWG
                     GVACLVMVPLILLHSGSKAPTQSLLGQIATAVGPLDKPFTRTDLHKQAW"
     gene            4496..6010
                     /gene="wzi"
     CDS             4496..6010
                     /gene="wzi"
                     /codon_start=1
                     /transl_table=11
                     /product="surface assembly of capsule"
                     /protein_id="BAT23445.1"
                     /translation="MPRALSILVFPSFSLRYDSGAENGSCTMIKIARIAVTLGLLSSL
                     GAQAYAAGLVVNDNDLRNDLAWLSDRGVIHLSLSTWPLSQEEIARALKKAKPSYSSEQ
                     VVLARINQRLSALKADFRVTGYTSTDQPGTPQGFGQTQPADNSLGLAFNNSGEWWDVH
                     LQGNVEGGERISNGSRFNANGAYGAVKFWNQWLSFGQVPQWWGPGYEGSLIRGDAMRP
                     MTGFLMQRAEQAAPETWWLRWVGPWQYQISASQMNQYTAVPHTKIIGGRFTFSPFQSL
                     ELGASRIMQWGGEGRPESFSSFWDGFTGHDNTGTDNEPGNQLAGFDFKFKLEPTLGWP
                     VSFYGQMVGEDESGYLPSANMFLGGVEGHHGWGKDAVNWYLEAHDTRTNMSRTNYSYR
                     HHIYKDGYYQQGYPLGDAMGGDGQLVAGKVELITEDNQRWSTRLVYAKVNPENQSINK
                     AFPHADTLKGVQLGWSGDVYQSVRLNTSLWYTNANNSDSDDVGASAGIEIPFSL"
     gene            6381..7412
                     /gene="wza"
     CDS             6381..7412
                     /gene="wza"
                     /codon_start=1
                     /transl_table=11
                     /product="putative capsule polysaccharide export protein"
                     /protein_id="BAT23446.1"
                     /translation="MVELPDSDYDLDKLVNVYPMTPGLIDQLRPETVLARPNPQLDNL
                     LRSYEYRIGVGDVLMVTVWDHPELTTPAGQYRSASDTGNWVNSDGTIFYPYIGKVQVA
                     GKTLSQVRQDIASRLTTYIESPQVDVSVAAFRSQKAYVTGEVTKSGQQPITNIPLTVM
                     DAINAAGGLAPDADWRNVVLTHNGKDTKISLYALMQKGDLTQNHLLYPGDILFVPRND
                     DLKVFVMGEVGKQSTLKMDRSGMTVAEALGNAEGMSQAFSDATGVFVIRQLKGDKQGK
                     IANIYQLNAQDASAMVLGTEFQLQPYDIVYVTTAPLVRWNRVISQLVPTITGVHDMTE
                     TAKFIKDWP"
     gene            7415..7849
                     /gene="wzb"
     CDS             7415..7849
                     /gene="wzb"
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="BAT23447.1"
                     /translation="MFDSILVICTGNICRSPIAERMLRKCLPHKRIDSAGVGAMVDNP
                     ADDMAIYISSKHGLSLTGHKGRQFSSSMAREYELILVMENKHIEEISKIAPQARGKVM
                     LLGYWMNSKQIPDPYRKSEEAFESVYQLIEKSCELWAAKLAK"
     gene            7866..10019
                     /gene="wzc"
     CDS             7866..10019
                     /gene="wzc"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="BAT23448.1"
                     /translation="MNTKDNRQQRSEANELELGRIVGELIDCRKLIIGITTGFTVIAV
                     LYALMATPIYQANALIQVEQKQGNAILSSLSQMLPDGQLQSAPEISLLQSRMILGKTV
                     DDLNLQTQVEKEYFPIIGKGISRILNNKNESIKIDKLYIERKEDSTDPEIIITIKDDK
                     HFTVEGDGFKVDGIKGEMLDKDKLRILITEINAEPGASFEVKYLSRLKAINNLLEAFN
                     VSDQGKDTGMLGLTLTGTDPNLISKTLNSIANNYLEQNVERQAAQDAKSLDFLNQQLP
                     KVRADLDIAEDKLNSYRKEKDSVDLSMEAKSVLDQIVNVDNQLNELTFREAEISQLYT
                     KEHPTYKALIEKRQTLQQEKTKLNKRVSGMPSTQQEVLRLSRDVESGRAVYLQLLNRQ
                     QELSIAKSSAIGNVRIVDDSITDPKPIKPKKILICIIGFILGLFFSVALIMLRFLLRR
                     GIESPEQLEEMGINVYASIPVSEWLLKASDKRKRKNNESDKLLAVENPTDLAVEAIRS
                     LRTSLHFAMLEAKNNVLMISGVSPNAGKTFVSTNLAATISLANKSVLFIDADLRKGYV
                     HKMLGNEGKSGLSDILSGQANVEETIISVPDGQFDYIGRGQVPPNPAELLMHPRFEKL
                     LAWASAKYDLVIIDTPPILAVTDAAIIGRYAGTTLLVARFESNTVKEIEVSITRFEQS
                     GVNVKGCILNGVVKKASSYYGYGYNYYGYNYSNKS"
     gene            10091..11236
                     /gene="wcuD"
     CDS             10091..11236
                     /gene="wcuD"
                     /note="orf7"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23449.1"
                     /translation="MNIVLFNTLYYPYRIGGAEVSVQILAEELVAKGNNVTVVSLSEG
                     LKQERDNIGGVKIIKLPIKNLYWPFNQKKQSKFKRLLWHIIDIYNPAYIKTVKDIFTE
                     TEPDVVHTNNLSGFSTSVWAVAKKNKIKIVHTARDYYLMHPNCTLFKNNENMNVKSLN
                     VKAWSFFKKKKSAKIDVFIGISEFITNLHKNNGFFRESLCTTIYNPVVVNAIKQGEST
                     QLTNKRVGFIGRLSEEKGFLEYCELAKNNRNYTFFAAGNYISEKEKERLSKFSNDANV
                     NVLGYVPVEKFFNMVDIVILPIKWNEPFGRVVVESVLAGKLVISRKVGSLPELSQILP
                     NIRLVDSLIDEFDEVVNSAVMSEVSEDVKKMFSPDNVANKYISAYKM"
     gene            11269..12273
                     /gene="wcuC"
     CDS             11269..12273
                     /gene="wcuC"
                     /note="orf8"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="BAT23450.1"
                     /translation="MNKKIIFLIIALTVTFSNKGLSFERGVCAHFDSYSEDPVVYLKA
                     LKQIGASSIRVDYQWNKIERTKGKYVVSRPLEKTDAAINQSSLYGLNNLLILDYGNSL
                     YDNGGYPTTRDGINAFANYTKWVVKKNKGKIKYYEVWNEWKNGTGMPPAMKNTGTAKG
                     YFEIVKRVSRIIKENDPNAIILAGSFNPLTDSDNAWFYELIELGILDYIDGISIHPYS
                     YKNENIQLRTAEANLNAIDQFYDKLTNIANRKTAIYITEIGIPNYDGIGGVNEIESSI
                     FRKNYIKLASERSYIKGVWWYDLKDDGTNKSFNEHNFGIFKANMTLKKNTDENLSLKN
                     "
     gene            12321..13553
                     /gene="wcuV"
     CDS             12321..13553
                     /gene="wcuV"
                     /note="HG53; orf9"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAT23451.1"
                     /translation="MKTIYESKSNEINNKSNLLTVVSLFFYILLFFAVNDGLRDTFSK
                     NYFPLSFLRDMSIFIGGLFCFFVIRKTPLTKKAIFLLIPLIMICTYSLITTLLVNQND
                     VYVRNLTTGGGLGFWMKALGTIFCFFIIYIYINNFHLSKVINSYIYFSFFYSLLTITI
                     IFFFPSYYHSLPSRNWYGRLSIGYPTQDVFVLALSLFFLLHSTISKGFKILIFITNVI
                     CLMMQNNATGYVLLATVFILTFIKGKMHVKFVSIVFFFVIIVSVYYFYNNYYLFDTFG
                     QLVKLKIDSLIYGTADSSSIDERLLQVTNTMRTIYSDPIYFLVGYGGLGGFAVESGAY
                     SIIGFSGFIGMTIYVFILLYALYYTIRERDFFMFGVIVLYILGSVSISSLYLTSTSWI
                     YAFILAYLSLNARTNIEA"
     gene            13610..14785
                     /gene="wbaZ"
     CDS             13610..14785
                     /gene="wbaZ"
                     /note="HG16; orf10"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23452.1"
                     /translation="MNHGIIMLENNISVGIVADWLVTYAGAERVVKEMIELFPDSDVY
                     SIVDFLSDEARANFNHKKSTTTFIQHLPKAKQKYQTYLPLMPLAIEQIDVSKHDVVLS
                     SSHAVAKGVLTGPDQLHISYVHSPIRYAWDLQHQYLKEAKLDKGLKGLLAKYLLHKIR
                     MWDVRTSNGVDHFIANSKFISRRVKKVYGRDADVIYPPVEVERFDFNDNKEDFYLTAS
                     RMVPYKRMDLIVEAFANMPDKRLVVIGDGSEMPKVKKKAASNIEILGYQPDQVLHDYM
                     RRAKAFVFAAEEDFGITPVEAQACGTPVIAYGKGGVLETVRPYGISNPTGLFFERQSI
                     SSLVETVKKFDKIQNLILPSDCKENSQSFSSDRFKRELNTYIEQKWKFFSDKKKIEY"
     gene            14846..16243
                     /gene="wcaJ"
     CDS             14846..16243
                     /gene="wcaJ"
                     /note="HG10; orf11"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23453.1"
                     /translation="MSKLHHRTKSKTNASLISILQRFSDIIMIFMGMYITNAIYQKMY
                     DSTALINSLIVLVCFQMIGGITDFYRSWRGVKISTELKIIIQNWTLSIVFTSGILSFL
                     AGNDLEIEFFFCWYIIVSLFLIVSRFSIRALMNVIRKLGYNTRIVALAGNIPVGINLM
                     KSFAEEPWLGLKVKGIYCDCPPTNSIGLPYSGKYEDLICEARKGEIDRIYIAMDMQDD
                     KKLKKLVKGLADTTCSVLLIPDIFTFNILQSRTEEVNGVPVVPLFDTPLNGINSVLKR
                     LEDIVLSLIILILISPVLIVIACIVKYSSKGPILFRQTRYGMDGKSIQVWKFRTMVVQ
                     ENGNVVTQAVRGDVRVTNVGRFLRRTSLDELPQFFNVLFGSMSIVGPRPHAVAHNEQY
                     RTLIEGYMLRHKVKPGITGLAQIKGWRGETDTLEKMQKRVEYDLEYIREWSLWLDLKI
                     IFLTVFKGFVNKSAY"
     gene            16260..17252
                     /gene="wcuE"
     CDS             16260..17252
                     /gene="wcuE"
                     /note="of12"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23454.1"
                     /translation="MKNNIYIDTRWKNAGGIGTFFEGVNNINQYTPLPFSGSPASPID
                     TFRMAFQLRNIKKGVVFLPGYISPFKTRLPYAVTVHDLNHLDRPENSSPLKIAYYNTF
                     LKRGCLHAEYVFTVSEFSRKRIIEWAGIEPSKVVNVGNGVSPKFQPEGERINLGYEYI
                     LCVSNRKGHKNEFGTLEAFKHADIDESIKLVFTGKANSEILEKINLLKLSNRVVFTGF
                     IPETELPKLYRSAKALIFVSFYEGFGLPVIEAMASGVPVVTSNTSSLGEISGDAALLA
                     NPNDTMDISKKLTQVINDFNVAKSLMAKGLVHSKKYTWHKTAKLIDDYLNKIHI"
     gene            17292..18302
                     /gene="wcuG"
     CDS             17292..18302
                     /gene="wcuG"
                     /note="HG25; orf13"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="BAT23455.1"
                     /translation="MSQTMRESWVDYAKGIGILLVVFGHVNRGLQAAGIIMPSKLYHL
                     VDSIIYSFHMPLFFFLSGLFFIKSIEKKGKLLLFIDKFKTIAYPYLVWSLLQGTIEVL
                     LSRFTNSKTSFTDLLMLFSHPRAQFWFLYALLMIFVLSIIIYSKRFFERGIIVLFVIF
                     SCVYIYSDKIGTVYNINYINQYMVFFVLGVFFNKFKLDDFFSKQLSGRYLFAIAVFLF
                     MAFLYSQYYFHFELKLHYFNIGIASLCLAFISIFFIVSVSLAIGRIHFPLLSLLGEMS
                     MIIYLLHILVASGSRVILMKVLHVNDWIAHLTIGLLAGIIIPILIYQYIKNTKLKYLF
                     SL"
     gene            18322..19335
                     /gene="wzy"
     CDS             18322..19335
                     /gene="wzy"
                     /note="HG58; orf14"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAT23456.1"
                     /translation="MIKNIYYFPANSGSNSYPARIKEILSKFSIVHDLYFSLLIKELV
                     KLNFTRYDIVIVNWLESGIIKKNGKLSFSGVIKVFIKLALLKAKFKKIIFVQHNKYPH
                     NTNIRFIKVATRIVNLIASFSDHVIIHSPVVCGNKYHYIPHPLYIYPIKSTEDSACSF
                     SNDNYYIFGRVVKYKKYEDVISAFPANKNLIIMGSCEDDEYKIMIQELCKNRKNVTFM
                     PEYISDEKAKELLSTGAALIISHSDEDMIVSGSFFYGLTIGIKILAINTPFLGWASSV
                     LQRDVIETFDDLDSMMHHIKTAQKGQSSRYSFQSIEDVNKYFGDISIESKFMSLLDIN
                     EKK"
     gene            19356..20789
                     /gene="wzx"
     CDS             19356..20789
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAT23457.1"
                     /translation="MNLINSAKWVAFSQFFKVIVQLVNIVYLARLIPPSEYGIMAMAL
                     VVINFGLLIRDLGTAAAIIQRKEIDDGIINSIFWLNLFMGLFIAVAIIFASPLIASFF
                     HTPKLIYVLLLISLIFPISSSSAAHLALLERASKFRVISLIEIFSALIGLISALILAY
                     QGYGVYSLVIQTIVLNIISTILFWKISKWRPQLSMMFKFSGLKQIVGFSVNLSLFNFV
                     NYFSRNTDSFIIGRFMPSSVLGAYSLAYRVMLFPLQSLTFVVSRSLLPILSHHQNDNA
                     IIRKTYSNCVFSILYLVVPLMSGLAYLSSPFVSVIFGNQWTLTAEILKWLAPTAIIQA
                     VLSSTGTVFIAKGRTDLLLKLGILGTFLYVLSFLIGVNFDIITFSKLYFIANVLNFFP
                     AMILMMRLIEGSLFTLLNKCFVIFFINFGMLAFLYFIDGLDFINAINEQVVYLILMIS
                     LGGGFYVLSSVLLIGKLRRFLLARFVN"
     gene            20974..22380
                     /gene="gnd"
     CDS             20974..22380
                     /gene="gnd"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate-6-phosphate dehydrogenase"
                     /protein_id="BAT23458.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA
                     ENPGKKLVPYYTVQEFVESLETPRRILLMVKAGAGTDSAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILKQIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLALSNEELAQT
                     FTEWNEGELSSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGLSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAQNAGIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRSAILPANLIQAQRDYFGA
                     HTYKRTDKEGVFHTEWLE"
     gene            22605..24020
                     /gene="manC"
     CDS             22605..24020
                     /gene="manC"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase"
                     /protein_id="BAT23459.1"
                     /translation="MLLPVIMAGGTGSRLWPMSRELYPKQFLRLFGQNSMLQETITRL
                     SGLEIHEPMVICNEEHRFLVAEQLRQLNKLSNNIILEPVGRNTAPAIALAALQATRHG
                     DDPLMLVLAADHIINNQPVFHDAIRVAEQYADEGHLVTFGIVPNAPETGYGYIQRGVA
                     LTDSAHTPYQVARFVEKPDRERAEAYLASGEYYWNSGMFMFRAKKYLSELAKFRPDIL
                     EACQAAVNAADNGSDFISIPHDIFCECPDESVDYAVMEKTADAVVVGLDADWSDVGSW
                     SALWEVSPKDEQGNVLSGDAWVHNSENCYINSDEKLVAAIGVENLVIVSTKDAVLVMN
                     RERSQDVKKAVEFLKQNQRSEYKRHREIYRPWGRCDVVVQTPRFNVNRITVKPGGAFS
                     MQMHHHRAEHWVILAGTGQVTVNGKQFLLTENQSTFIPIGAEHSLENPGRIPLEVLEI
                     QSGSYLGEDDIIRIKDQYGRC"
     gene            24007..25413
                     /gene="manB"
     CDS             24007..25413
                     /gene="manB"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="BAT23460.1"
                     /translation="MVVANFIRDKRRMTQLTCFKAYDIRGELGEELNEDIAYRIGRAY
                     GEFLKPGKIVVGGDVRLTSESLKLALARGLMDAGTDVLDIGLSGTEEIYFATFHLGVD
                     GGIEVTASHNPMNYNGMKLVRENAKPISGDTGLRDIQRLAEENQFPPVDPARRGTLRQ
                     ISVLKEYVDHLMGYVDLANFTRPLKLVVNSGNGAAGHVIDEVEKRFAAAGAPVTFIKV
                     HHQPDGHFPNGIPNPLLPECRQDTADAVRAHQADMGIAFDGDFDRCFLFDDEASFIEG
                     YYIVGLLAEAFLQKHPGAKIIHDPRLTWNTVDIVTRSGGQPVMSKTGHAFIKERMRQE
                     DAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELLCLKNSSLKSLVADRQAAFPASGEI
                     NRKLGNAAEAIARIRAQYEPAAAHIDTTDGISIEYPEWRFNLRTSNTEPVVRLNVESR
                     ADTALMNAKTEEILALLK"
BASE COUNT     7529 a   5041 c   5907 g   7442 t
ORIGIN
        1 ccgaggtaca acgcgcgacg tcataatact gctgacgctg cgctgattaa ggttcagcac
       61 ccgctcaatc atcagtcgtt cctgcggatt aaacagagga tgttgatcct gatcggcgac
      121 cagcgacgcc gtgtcagcat ccagttcagc tttttctttc tgcccgctca gcagattcat
      181 caccgcttcg gtagtgcgct gacgcagcgt catattggcg gagaggaagc gacggcggtt
      241 aaactgcgcc agctgattaa gcgcttcaat catgaccgag aagccaatgg ccgcatatag
      301 atagcctttc ggaataataa agctgaagcc ttcagcaatc agactaaagc cgatcatcag
      361 caggaagctc agacagagga tcacgatggt cgggtggctg ttaacgaagc gcgtcagcgc
      421 cttgctggcc atcagcatca ggctgatggc gataaccacg gcggccatca tcaccgccag
      481 gtgatcgacc atgccgacgg cggtgatcac cgagtcaagc gagaagatgg cgtcgagcac
      541 cacgatctgc gccacgacgg cccagaattt cgcccctttg cgctgggtgg ggttatcgct
      601 gtctttcccc tccagccgct cattaagctc gacggtcgct ttaaacagca gaaacaggcc
      661 gccaaacagc ataattaaat cgcgggcgct aaagctgaag tcgtgaaaaa caatcagcgg
      721 tttggtcagg gtgaccagcc aggagataga ggccagcagc agaagacgca tgaccatcgc
      781 cagcatcagg ccagtgatcc gcgcgcggtc acgctgggcg ggagggagct tctcggcgag
      841 gatagcgata aagaccaggt tatcgatacc caacaccagt tcgataacca ccagcgtgac
      901 gagacctgcc cagattgacg gatcggcaat ccattccata tgtattaaaa cctgtacgac
      961 tgcggtatgt gttaccacga tcatggataa gatgagtcta aaatgcaata acgacgcgga
     1021 tatcgccctg ccgtgggtgg atatatttcc agcggattaa gcgaaccgat aagaattatg
     1081 ttccggaaaa gaacagtgaa aaaataacac catggcggcg accatggaat aagcttgccg
     1141 atatcagaac tttttccgct gcgtttcagc gagggcggca aaagggcttc ctcccgcggt
     1201 tcgtcacggc gagcgcggat gcgcagagca gaagcgaagc gcgaagcccg ctcacaaaac
     1261 cggcataatt catattatga agtgagtgca gaatagggcg gatcgcagtt caccgtcgcg
     1321 gattcaggct aatatgtcgt catatccggc tgtttatgct gaaatatatt gcctggcgaa
     1381 atttattatc tctatctatt ctttccaggc atacgcgcgg cgcggcgggg ccggcggcca
     1441 gcagaccccg atagacgggc ctctcagcca catcgcgcgg cgcaaaggaa catgccgctg
     1501 aataacctga acgaaaataa gattattctc acttctgact gttggtaaaa gggagttgtg
     1561 tgtattcttt tacgtgacag tgaatttaag aatttggcgg gcagatgccc gggcagtatc
     1621 cgtgtattat cagtttcaat ggatttgtga catgtacaat tttgcaaaac cgcgtgtttt
     1681 gcaaccaaac aggtgaagat gaatatggcg aatttgaaag cggttattcc ggtcgcagga
     1741 ctaggcatgc atatgctgcc ggccacaaag gcaattccaa aggagatgct gccgatcgtt
     1801 gataagccaa tgattcagta catcgttgac gaaatcgtcg ccgccgggat caaagagatt
     1861 gttctggtga cgcactcctc gaagaacgcg gtggaaaacc acttcgacac ctcctacgag
     1921 ctggaagccc tgctggaaca gcgcgtgaag cgccagctgc tggcggaagt gcaggccatt
     1981 tgcccgccgg gcgtgaccat catgaacgtg cgtcaggcgc agccgctggg cctgggccac
     2041 tccatcctct gcgcccgccc ggtagtcggc gacaacccgt ttgtggtggt cctgccggat
     2101 atcatccttg acggcggcac cgctgacccg ctgcgctata acctcgccgc tatgatcgcc
     2161 cgctttaacg agaccggccg cagccaggtg ctggcgaaac gcatgccggg cgatctctcc
     2221 gaatactccg tcatccagac caaagagccg atggtggctg aaggccaggt agcgcgtatc
     2281 gtcgagttta ttgaaaaacc ggacgaaccg cagaccctgg actccgatct gatggcggtg
     2341 gggcgctacg tgctgtcggc ggatatctgg gccgaactgg aacgtaccga gccgggcgca
     2401 tggggccgta tccaactgac cgacgccatt gccgaactgg cgaagaagca gtccgtcgac
     2461 gcgatgctga tgaccggcga aagctacgac tgcgggaaga aaatgggcta catgcaggcc
     2521 ttcgtcacct acgggatgcg taacctgaaa gaaggcgcca aattccgcga aagcattaaa
     2581 aaactgctgg cctgagcgcc agcctgaaac cgagcggcaa ggctgaagca ttcgtcctgc
     2641 cgctcataac gttatgcaga aattattcat aacgcgaatg ttataacgat tgtaaagaaa
     2701 cgtatggctt cggagacttc tggtagtttg tctctggcct ctgtggtgca atggtcggag
     2761 tagcggcaat aatgctttat gaatagtcac ttagtgcgac aattcctaaa gcgaagggaa
     2821 agcggtcaac gacagccaaa aataaaactt gactgcgatc atgtttccgc tttaaacatc
     2881 tcacttgcat gcataaaaat gtgaaatgaa ttggcatgcg agctggtaca gacattacgg
     2941 ataatccctg agcacggcag tggacatcat cgaaggatca caggtatatg aactggcaac
     3001 tcatctcatt ttttggcgat agcaccgttt tgctgcccag cgcagcggcg ctgtttattg
     3061 tcctgatgct gcgtaaaacg tcgcggttac tggcgtggca gtggagtttg ctgttcggca
     3121 tcaccggcgc tatcgtgtgc gcctccaaac tggcctttat gggctggggt ctgggtattc
     3181 gcgagctgga ttacaccggc ttcagcggcc actccgcgct ctccgcggcc ttctggccta
     3241 tctttctgtg gctgctcagc gctcgttttt ccgcgggttt gcaaaaagca gccgtcgcca
     3301 ccggctatat tctggccgcc gtggtgggct attcgcggct ggtcatccat gcgcattccg
     3361 tctcggaagt gattgccggc ctgctgctgg gcgctgctgg cagcgctttg ttcctggtgt
     3421 tgcaaaaacg tacccctgat ccggaaagcg tgaatatctc atggggcggt gttgcatgcc
     3481 tggtgatggt tccgcttatc cttttacata gcggcagcaa agcgccgact cagtccctgc
     3541 tgggacaaat cgccaccgcg gtggggccgc tggataaacc ctttacgcgt accgatctcc
     3601 acaagcaggc ctggtaatcg ccatttgttt tacaggggaa attaagtttt cgccggttaa
     3661 ttagacaaat aagaaaataa tctactatat acccggtaat tgataattca tatttatgaa
     3721 ataatgaagt gctactacat tgttattgca tatttgcctg gatatagcct tgatcagacg
     3781 tttcttaaat gcgctgagac gttacctgat gcacattcaa tgaatatcca gacacaggaa
     3841 actattagaa attgtagttg actataacgc catcatctga tttttgcatg atgatgagct
     3901 atggaaaaag acgttttttt acagtcagtt agctgcatgt gtgatgttgt agcagtaccg
     3961 ggaagatttc taaccctgga aatcagtgaa taatcttaat tggtgacccg cttatttttt
     4021 gtcagtagaa cgacaggcgg cattaattgg cagatattcg gtaacaacac tcccaattgt
     4081 gaccgaaatc ccgtaaactt aacgccgcca aaaataatgg cctgaccaat tattcatcca
     4141 caggtcgata aaaattaagt cgttcaggta gtcagtgcgc tggtagctgt taagccaggg
     4201 gcggtagcgt cgctgaagcc gcttgctgct gcacagaggt tctcttcaac ggctgtaagt
     4261 atcgacccgg tcaggatgat catcatcaat agatatctac caattttcta cggatatcct
     4321 cagaagttgg ccaggagcgg ctgctaatat cgcctggata ttaactttcc tgtctcatcc
     4381 atagcctgta gggtaaaatt cgcctacatt gtgagctgag tggatgttat aaggctaaca
     4441 agcagcttag ggtaaatgta cttgcctcgc cggtgttgca cagcgaagtc agctggtgcc
     4501 gcgagcgctt tctatcttgg tattcccctc attctcattg agatacgaca gcggggctga
     4561 aaatggatct tgtacaatga taaaaattgc gcgcattgcc gtgacgttgg gtttgctttc
     4621 ctccctggga gcccaggctt acgcggccgg gttagtggta aatgacaacg acttgcgtaa
     4681 cgacctggcc tggctttccg atcgcggggt catccatctg agcctgtcga cctggccgct
     4741 cagccaggaa gagattgccc gggcgctgaa aaaggccaaa ccgtcctatt cttctgaaca
     4801 agtggtgctg gcgcgtatta accagcgcct gtctgcctta aaagcggatt tccgggttac
     4861 cggctacact tcaaccgatc agccgggcac tccgcagggg tttggtcaga cacagccggc
     4921 agataactcg ttaggcctgg cgttcaacaa cagcggcgag tggtgggatg tccacctcca
     4981 gggcaacgtc gaaggagggg agcggatcag caacggctcg cgcttcaacg ccaacggcgc
     5041 atacggcgcg gtgaagttct ggaaccagtg gctctctttt ggtcaggttc cgcagtggtg
     5101 gggacctggc tatgaaggta gcctgatccg cggggatgcg atgcggccga tgaccggttt
     5161 cctgatgcag cgcgcagagc aggcggcgcc ggaaacctgg tggttacgct gggtggggcc
     5221 atggcagtac cagatctccg ccagccagat gaatcaatat accgctgtgc cacatacaaa
     5281 aattatcggc ggtcgtttta ctttctcacc tttccagtca ctggaattag gtgcttcgcg
     5341 cattatgcaa tggggcgggg aagggcgtcc tgagtcattt agcagcttct gggatggctt
     5401 cactggccat gataataccg ggacggataa cgaaccgggt aaccagctgg ccggatttga
     5461 ctttaaattc aaactcgagc cgactctagg gtggccggtg agtttctatg ggcaaatggt
     5521 cggcgaggat gagtctggct acctgccttc cgcgaatatg ttccttggtg gagtggaagg
     5581 gcaccacggc tggggtaagg atgcagtgaa ctggtatctg gaagcgcatg atacacgtac
     5641 aaatatgagt cgaaccaatt acagctaccg tcaccatatt tataaagatg gatattatca
     5701 gcagggttat ccgctgggtg acgcaatggg cggtgatggt caactcgttg ccggtaaggt
     5761 tgagctaatt acggaggata accagcgctg gagtacgcgc ctggtttacg ccaaagttaa
     5821 cccggagaat cagtcgatca ataaagcatt cccccatgcc gataccttga aaggtgtaca
     5881 gctcggttgg agcggggatg tgtatcagtc ggtacgtttg aatacatcac tgtggtacac
     5941 caacgcgaac aacagcgaca gcgatgacgt tggggccagc gcagggatag agataccgtt
     6001 tagtttataa ggctgaatgc tgaaaatagg ggagagaggg tggtagcgct gcaggacgcg
     6061 gtcagttttt ttctctccgt aagcctgcag ggaagtaacg gctaacacag ctgctcagga
     6121 attggcaaat tttggtttac tgatgatgtg acattatgaa gaaaaaactt gttagatttt
     6181 cggcattagc attggcaatt gaaaccaata atgaatttaa ttaatagcgc aaaatgggtt
     6241 gccttttctc agttcttcaa agttattgtt cagttagtaa atattgttta tctggcaaga
     6301 ttaatacccc ctagtgaata tggtttttat cgggttgtac aatcatccct ggtcagggat
     6361 taaacagtct gcgtaagaac gtggttgaac tcccagatag tgattacgat ttggataagt
     6421 tggtcaatgt atatccgatg acaccaggat tgattgatca acttcgccca gaaaccgttc
     6481 tggctcgtcc caatccgcaa ctggataact tactccgtag ttatgaatat cgcattgggg
     6541 taggtgacgt actgatggtt accgtatggg accaccctga actaactact cctgcaggcc
     6601 aataccgcag cgccagcgat accggcaact gggttaactc cgacggtacc attttctatc
     6661 cttatatcgg taaagtgcag gtggcgggga aaacgcttag ccaggtacgc caggatatag
     6721 ctagccgttt gacaacatat attgaaagtc ctcaagtaga tgtaagtgtg gctgcatttc
     6781 gttcgcaaaa agcctatgtg acaggtgagg ttactaaatc aggacagcag ccaattacca
     6841 atatcccatt aacggtgatg gatgccatta atgcggcagg tgggcttgca cctgatgccg
     6901 actggcgaaa tgttgtatta acacataacg gaaaagacac aaaaatctca ttatatgcat
     6961 taatgcagaa aggggatttg acccaaaatc atctgttata tccaggcgat attctttttg
     7021 tgccgcgtaa tgacgatcta aaagtatttg tcatgggtga ggttggtaaa caaagtactt
     7081 taaaaatgga tcgcagtggt atgacagttg ctgaagcctt aggaaatgct gaaggaatgt
     7141 cgcaggcctt cagtgatgct actggggtat ttgttattcg ccagttgaag ggtgataagc
     7201 aaggtaaaat agctaacatt taccagctaa atgcacaaga tgcttcagca atggttctgg
     7261 gaacagaatt tcaattacaa ccgtacgata ttgtttatgt tacaacagca ccattggtac
     7321 gatggaatcg tgtaatctcg caacttgtac caacaattac cggcgttcat gacatgacag
     7381 aaacagcaaa attcatcaag gattggccat agtaatgttt gattcaatat tagtaatttg
     7441 tactggcaat atttgtcgct ctccaattgc tgagagaatg ttgcgtaaat gcttacctca
     7501 taaaagaatt gattctgctg gagttggcgc aatggtcgat aatccagcgg atgatatggc
     7561 aatatatata tctagtaaac atggattaag tttaactggt cacaaaggta ggcagttttc
     7621 ttcttcaatg gcaagagaat atgaactcat cttagttatg gagaataagc acatagaaga
     7681 aatatctaag atagcacctc aagcaagagg taaggtaatg ctattaggat attggatgaa
     7741 ttcaaagcaa atacccgatc catatcgtaa aagcgaggaa gcatttgaat cggtatacca
     7801 actgatagaa aaatcttgcg aactatgggc tgctaaatta gcaaagtaat tctgggaaac
     7861 atataatgaa cacaaaagat aataggcaac agcgttctga agcaaacgaa cttgagcttg
     7921 ggcgtatcgt tggtgagctt atcgattgta gaaagcttat tattggcatc actacagggt
     7981 ttactgttat cgcagtattg tacgctttaa tggctacccc tatctatcaa gcaaatgcgc
     8041 ttattcaagt cgaacaaaag caaggcaatg caatattaag tagtttgagt cagatgttac
     8101 ctgatggtca acttcagtca gctcccgaaa tatcattatt acaatcacga atgatactgg
     8161 gaaaaacagt tgacgatttg aatttacaaa ctcaagtgga aaaggaatac tttccaataa
     8221 tagggaaagg tatctcgaga atcttaaata ataaaaatga atctattaaa atagataagt
     8281 tgtatattga gagaaaagaa gattcaacag accctgaaat aattatcacg attaaggatg
     8341 ataaacactt tactgttgaa ggtgatggtt ttaaagtgga tggtattaaa ggggaaatgt
     8401 tagacaagga taaattacgg atcttaatca ctgaaattaa tgctgagccg ggtgcaagtt
     8461 ttgaagtaaa atatttaagc cgtctaaaag caataaataa tttacttgag gcgtttaacg
     8521 tatccgatca aggaaaagat acgggaatgc taggcctgac tctcacaggt acagatccga
     8581 atttaatatc taaaacttta aatagtatag ctaataatta tttggaacaa aatgttgagc
     8641 gacaagcagc acaagatgcg aaaagtttag atttcttgaa ccagcagttg cctaaagttc
     8701 gcgctgattt agatattgca gaagataaac tgaattctta tagaaaagaa aaagattctg
     8761 ttgacctttc tatggaagct aaatctgttt tagatcaaat agttaatgtc gataatcaac
     8821 taaatgaatt aacatttaga gaagctgaga tttcacaact atacaccaaa gaacatccaa
     8881 catataaagc gttgattgaa aaacggcaaa ctttgcagca agaaaaaact aaactaaata
     8941 aacgcgtaag cggaatgcca tcaactcaac aagaagtcct gaggttaagc cgtgatgttg
     9001 aatcaggaag agctgtatac ctacaacttt taaatcgtca acaggaacta agtattgcaa
     9061 aatcgagcgc gattgggaat gtcagaattg ttgatgattc aattacagat ccgaagccaa
     9121 ttaagcctaa aaaaatattg atttgcataa tcggatttat tctgggtctc tttttttcag
     9181 tcgcattaat aatgttgcga ttccttctca gaagaggtat tgaatctcca gaacaattag
     9241 aagaaatggg aattaatgtt tatgcaagta ttccggtttc tgagtggtta ttgaaagctt
     9301 cagataagag gaaaaggaaa aataatgaat cagataaatt actggcagtg gagaatccta
     9361 ctgacttggc tgttgaagct ataaggagtc taaggactag tttgcatttt gctatgttag
     9421 aggcaaaaaa taatgttcta atgatttctg gtgtaagccc aaacgcaggc aaaacattcg
     9481 ttagtaccaa tttagccgca acaatttcgc tagcaaataa gtcagtacta tttatagatg
     9541 cggatttaag gaaaggctat gtgcataaaa tgttaggtaa cgaaggcaaa tctggcttat
     9601 ctgacatact ttcggggcag gctaatgtcg aggaaacaat tatctctgta cccgatgggc
     9661 aattcgacta tatagggcgc gggcaagtgc ctcctaatcc tgctgaactt ttgatgcatc
     9721 cacggttcga aaagttgctt gcttgggcat ctgcaaaata tgatttagtc attatcgata
     9781 cacctccaat tttggcagtt acagacgcag caataattgg tcgatatgct ggaaccacac
     9841 tacttgtggc acggtttgaa tctaatacag ttaaagaaat tgaagtaagt ataacgcgtt
     9901 ttgaacagag tggcgtcaac gtaaaaggat gtatattaaa cggagtagtc aaaaaagcta
     9961 gtagttatta tgggtatgga tacaattact atggatacaa ttattcaaat aaatcttaat
    10021 atttaatatt aactttaaac aaattaggca tgttaatgag catgcctaac aagtttttat
    10081 aggtgataaa gtgaacattg tgttatttaa tacgctatat tatccatata gaattggcgg
    10141 tgctgaggtt tcagttcaaa tacttgctga agaattagtc gctaaaggaa ataatgttac
    10201 agtagtttct ttatctgaag gattgaaaca ggaaagagat aatattggtg gtgtgaaaat
    10261 cataaagtta ccaataaaaa atctctattg gccatttaat caaaagaagc aaagtaaatt
    10321 taagagatta ttatggcata taattgatat ttataaccct gcatatatta aaactgtaaa
    10381 agatattttt acggaaacag aacctgatgt tgtgcatacc aataatctat cagggttttc
    10441 aacctcagta tgggccgttg ctaaaaaaaa taaaataaaa atagtccaca cagcaagaga
    10501 ctattatctc atgcacccta attgtacact ttttaaaaac aatgaaaata tgaacgttaa
    10561 gtctcttaac gtaaaagcat ggtcattttt taagaagaaa aaaagcgcaa aaatagatgt
    10621 tttcattgga atcagtgagt ttataacaaa tctacataaa aataatggct tttttagaga
    10681 atctttatgt acaacaatat ataatcccgt agtggtaaat gctatcaagc aaggcgaaag
    10741 cactcagtta acaaataaac gtgtaggatt tatagggcga cttagtgaag aaaaaggatt
    10801 tctggaatac tgcgaactag ctaaaaataa tcgaaattat actttttttg cggctggtaa
    10861 ttatataagt gagaaagaaa aggagaggct aagtaagttt tctaatgatg ccaatgtcaa
    10921 tgtccttggg tatgttccgg ttgaaaaatt ctttaatatg gttgatattg tgatactacc
    10981 cataaaatgg aatgaacctt tcggaagagt ggttgttgag agtgtattag caggtaaact
    11041 agttatatct agaaaggttg gctctctacc tgagttaagt caaatcctgc caaatattag
    11101 attggttgat tcgttaattg atgagtttga tgaagttgtt aatagcgctg taatgtcaga
    11161 agtttctgaa gatgtaaaaa aaatgttttc gccagataat gtggcaaata aatatatttc
    11221 tgcatacaaa atgtagtttt taactaccaa taatatcaag aggagctgat gaataaaaaa
    11281 attatctttc tcataatagc gttaactgtt acttttagta ataaaggctt gtcctttgaa
    11341 cgtggtgtgt gtgctcattt tgatagttat tcagaagatc cggtagttta cttaaaggca
    11401 ttaaaacaaa tcggtgcaag ttcaataaga gttgattatc aatggaataa aattgaacga
    11461 accaaaggta agtatgttgt ttcgaggcct ttagagaaaa cggatgctgc tattaaccaa
    11521 tcatcgttat acggtctaaa taatctcctt attttagatt atggtaattc tctatacgat
    11581 aatggaggat atccaacgac cagagatggt atcaatgcat ttgctaatta tacaaaatgg
    11641 gttgtaaaaa aaaataaagg taagattaaa tattatgaag tatggaatga atggaagaat
    11701 ggcactggca tgccgccagc aatgaaaaac acaggcactg caaaaggata ttttgaaatt
    11761 gtaaaaagag ttagtcgtat catcaaagaa aatgatccca atgctattat tctggctgga
    11821 tcatttaatc ctcttaccga cagtgataac gcatggttct atgaattgat agaactagga
    11881 atacttgatt atattgatgg tatatcaatc catccgtatt cttacaaaaa tgaaaacatt
    11941 caattgagga ctgctgaagc aaacttaaat gcaattgatc aattttatga taaattaaca
    12001 aacattgcta atagaaaaac tgctatctat attacagaaa ttggaatacc aaattatgat
    12061 ggaataggag gtgtcaatga aattgaatca tctattttcc gaaaaaatta tattaaatta
    12121 gcgtcagaac gctcatatat caaaggcgta tggtggtatg atttaaaaga tgatggaact
    12181 aataaatctt ttaatgagca caattttgga atttttaaag ccaacatgac tttgaaaaag
    12241 aatactgacg agaatttatc tttaaaaaat taaagtatac attcacatta aagttttatc
    12301 tattatatga caatgacatt atgaaaacaa tatatgagtc aaagagtaac gaaattaata
    12361 ataaaagtaa tttactaacc gtagtaagtt tattttttta tattttacta ttctttgctg
    12421 tcaatgatgg attacgagat acgttttcaa aaaactattt cccattgtca tttctaagag
    12481 atatgtctat ttttattggc gggctatttt gcttctttgt gataaggaaa acgccattaa
    12541 ccaaaaaggc gatcttttta ctcattccac tcataatgat ctgtacatat tctttgatca
    12601 caacattgct agtaaaccaa aatgatgtgt atgtgcgaaa tcttacaact ggtggagggc
    12661 ttggattttg gatgaaggca ctagggacaa ttttttgctt ttttattata tatatttata
    12721 taaataactt tcatttatca aaagttatta attcttatat atatttttca ttcttttatt
    12781 cattgttgac aattactata attttctttt ttccatcata ttatcatagt ctcccctcaa
    12841 ggaactggta tggaagacta tcaattggct atcctacaca agatgtattt gtattagcac
    12901 tttcattgtt ttttttgtta cattcaacga tttccaaggg ttttaaaata ctaattttta
    12961 taacgaatgt tatttgccta atgatgcaaa acaatgccac aggctatgtt ttattggcaa
    13021 ccgtattcat tcttactttt attaaaggta aaatgcatgt caagtttgta tcaattgttt
    13081 tcttttttgt cataatagtt agcgtgtatt acttctataa taattattat ttattcgaca
    13141 catttggaca gttagtaaaa ttaaaaattg attccttaat ttatggtact gcggacagtt
    13201 cttcaattga tgaaagactt cttcaagtaa ctaatacaat gagaacgata tattctgatc
    13261 ccatttattt tttagtaggg tatggtggct taggcggatt cgctgtggag tcaggagcat
    13321 attctattat cggtttctct gggttcattg gtatgacaat ttatgtgttc atattacttt
    13381 acgctttata ctatacaatt agagaaagag atttttttat gtttggtgta attgtattat
    13441 atatattggg aagtgtttca attagttctt tatatcttac atcaacatca tggatatatg
    13501 catttattct tgcatatcta tctctgaatg caagaacgaa tattgaagca tgaggattaa
    13561 ttttaaataa aatatatctg agtaaagccg gtttccgaat acacatcata tgaatcatgg
    13621 aattattatg ttagaaaaca atataagtgt tggaatagtt gctgattggt tagttacgta
    13681 tgcaggggct gaacgtgttg taaaagagat gatagaattg ttccctgatt ctgatgtcta
    13741 ttctattgtg gacttcttat ctgatgaagc tagggctaat tttaatcaca agaagtccac
    13801 aacaaccttt atacagcatt taccgaaagc gaaacagaaa taccaaactt atctaccact
    13861 gatgccatta gcaatagaac agatcgatgt atcaaaacat gatgtcgttt tgtcaagtag
    13921 ccatgccgta gcaaagggtg ttttgactgg accagatcaa ttacatatca gttatgtgca
    13981 ttcacctatc cgatacgcat gggacttaca gcatcagtat ctaaaagaag ccaaactaga
    14041 taaagggctc aaaggtttac tagctaagta tttacttcat aagattagaa tgtgggatgt
    14101 gagaacttca aatggagttg atcattttat tgcgaactca aaatttatct caaggcgtgt
    14161 aaaaaaagtc tatggtagag atgcggatgt tatttatcct cctgtcgaag tagagcggtt
    14221 tgattttaat gacaacaaag aggattttta tttaacggct tcacgcatgg tgccttataa
    14281 aagaatggat ctcatagttg aagctttcgc taacatgccg gataaaagat tagtggtcat
    14341 tggtgatggc agtgaaatgc ccaaggtaaa gaaaaaagca gcatctaata ttgaaatttt
    14401 aggctatcaa cctgatcagg ttcttcatga ctatatgagg agagcaaaag cttttgtttt
    14461 tgcagcagaa gaagattttg ggattacacc agttgaagca caagcgtgtg gaacacctgt
    14521 tattgcatat ggcaaaggag gtgtgcttga aacggtgaga ccctatggaa taagcaaccc
    14581 aacagggctc ttctttgaaa ggcaatctat atcttcctta gttgagacag ttaaaaaatt
    14641 tgataaaatc cagaatttaa tattaccttc agattgtaaa gaaaattcac aatctttttc
    14701 ttccgaccgc tttaaaagag aactcaatac atatatagag cagaaatgga aatttttttc
    14761 agataagaaa aaaatagaat actaattctt agctgaacgt tatgaatgag ttatagatgt
    14821 ctaaacaaag aaatttggac cgaatatgag taaactacat catagaacga agtcaaagac
    14881 taatgcatca ttgatatcaa tactacaaag attctccgac ataattatga tatttatggg
    14941 gatgtatatt acaaatgcaa tatatcaaaa aatgtatgat tctactgcat taataaatag
    15001 cctgattgta cttgtttgtt tccagatgat tggtggtatt acagattttt atagatcctg
    15061 gcgcggggtg aaaatttcta cggaattgaa gattataatt caaaattgga cattaagtat
    15121 tgtatttacg tcaggtattt tatcatttct agcaggtaat gatttagaaa tagagttttt
    15181 cttttgttgg tatattattg taagcctttt ccttattgtc agtcgttttt ccattcgggc
    15241 actaatgaat gttattagga aattaggcta taacacgcgt attgtagctc tagcgggaaa
    15301 tatacctgtt ggtattaatc tgatgaaaag ttttgccgag gaaccatggc ttggattaaa
    15361 agtaaaaggt atttactgtg attgcccccc aacgaactca ataggtctac cttatagtgg
    15421 gaaatatgag gatttaatat gcgaagcccg taaaggagag attgacagga tatatatagc
    15481 aatggatatg caggacgata aaaaattaaa gaaattagta aaaggattgg ctgataccac
    15541 atgttctgta ttgctaattc ctgatatctt cacatttaac atccttcaat cacgtactga
    15601 agaagttaat ggtgtccctg ttgtaccgtt attcgacact cccctaaacg gcataaacag
    15661 tgttttgaaa agactggaag atattgtcct ttctttgata attttgatat taatatcccc
    15721 tgtattgata gtcattgcat gcatagtaaa atattcctcc aaaggaccta ttttattccg
    15781 acaaacgcgg tatgggatgg acggaaaatc tatacaagta tggaaattca ggactatggt
    15841 tgtacaagag aacggcaatg ttgttacgca ggcggtacgt ggagatgtgc gtgttactaa
    15901 tgttgggcgg tttttaagaa gaacatcact tgatgagtta ccgcagtttt ttaatgtttt
    15961 atttggtagc atgtctattg ttgggccgag accccacgcg gtggctcata atgagcaata
    16021 tagaacatta attgaagggt atatgcttag gcataaagtt aaaccaggaa ttacaggctt
    16081 agcacaaatt aaaggatgga ggggggaaac tgatacactt gaaaaaatgc aaaaacgagt
    16141 ggagtatgat cttgaataca ttcgtgagtg gagtttatgg ttggatttaa aaattatatt
    16201 tttgacggtg tttaaagggt tcgtcaataa atcagcatat taatacatgt gagacagaaa
    16261 tgaaaaataa tatttacatt gataccagat ggaaaaatgc tggaggtatt ggtacatttt
    16321 ttgagggagt taacaatata aatcagtata cacctttacc attcagcggt agccccgcgt
    16381 caccaataga tacattcagg atggcgttcc agttgaggaa cataaaaaaa ggagtggttt
    16441 ttttgccggg ttatatttct ccttttaaaa caagacttcc atacgctgta acagttcatg
    16501 atttaaatca cttagatcga ccagaaaaca gtagcccttt aaaaatagct tattataaca
    16561 cctttctcaa aagaggctgt ttgcatgcgg aatatgtatt tactgtttcc gaattctctc
    16621 gtaaaagaat tattgaatgg gcaggcatcg agccaagtaa agtcgtgaat gtcggaaatg
    16681 gtgtatcacc aaagttccaa ccagaaggtg agagaataaa tttaggatat gagtatatat
    16741 tatgcgtaag taatagaaaa ggacataaaa acgaatttgg tactctagag gcctttaaac
    16801 atgcagatat tgacgaaagt attaagttag tctttacagg aaaagctaac tctgaaatct
    16861 tagaaaaaat aaatttatta aaacttagta atagagtggt cttcactggt tttattcctg
    16921 aaactgaact tccaaaatta taccgatctg caaaggcttt aatctttgtg tcattttatg
    16981 aagggttcgg cttgcctgta attgaggcga tggctagcgg tgtaccggtg gtcacttcaa
    17041 atacatcttc tctaggtgag atttctggtg atgctgctct attagctaat ccaaatgata
    17101 caatggatat ttcaaaaaaa ctcactcaag tcataaatga ttttaatgtc gctaaatcat
    17161 taatggcaaa aggattagtt cattcgaaaa aatatacatg gcacaaaaca gcaaaactta
    17221 ttgatgatta tcttaacaag atacatatat aaatagtaaa ctattatctt acttaataag
    17281 gctgttaatt aatgagtcaa actatgcgtg aaagttgggt cgactatgct aagggaatag
    17341 gtatcctact ggttgtcttt ggacatgtta atagaggatt gcaagcagct ggaattatta
    17401 tgccatcaaa actttatcat ttggttgata gtataatata ttctttccac atgcctttgt
    17461 ttttttttct gtctggcttg ttttttatta agtcgattga gaagaaagga aagttgcttc
    17521 ttttcattga taaatttaaa acgattgctt atccttattt agtatggtca ctacttcaag
    17581 gcacgattga ggttttattg tcaaggttta caaactcaaa gacctcgttt accgatctgt
    17641 tgatgctatt ttcacatccg cgtgcgcaat tttggttttt atatgctctt ttgatgatat
    17701 ttgtactatc aatcataata tactcaaaac gattttttga acgcggcata atagttttgt
    17761 tcgttatttt ttcttgcgtg tatatatata gtgataaaat tggaactgtc tataatatca
    17821 attatatcaa tcaatatatg gttttttttg ttttaggggt attttttaat aaatttaagt
    17881 tagatgattt tttttctaag caattaagcg gacgttattt atttgcgata gctgtgtttt
    17941 tattcatggc atttctttat tcgcaatatt attttcactt tgaattaaaa ttgcattatt
    18001 tcaatattgg aattgctagt ttatgtctcg catttatatc aatttttttc attgtttctg
    18061 tatcgttagc aataggtcgt attcatttcc cgttactatc gcttctagga gaaatgagta
    18121 tgattattta tttattacat atcttagttg ctagtggttc aagagtgatt ttaatgaaag
    18181 ttcttcatgt taatgattgg attgcacatc taacgattgg tttgcttgcg ggtataatta
    18241 ttcccattct catttatcaa tacattaaaa atactaagct taagtacttg ttttctcttt
    18301 aagatatacg gggcgtataa aatgattaag aatatttact attttcctgc aaatagtggt
    18361 tcaaatagtt atccagcgcg aataaaagag attttatcga agtttagtat tgttcatgat
    18421 ttatatttta gccttcttat taaagagttg gtgaaactaa attttacacg atatgatatc
    18481 gtaattgtaa actggttaga atcgggaata attaagaaaa atggtaaatt gtctttttct
    18541 ggtgtgatta aggtttttat taaattagcc ttattgaagg caaaatttaa aaaaataata
    18601 tttgtccagc acaataaata tccacacaat acaaatatta ggtttatcaa agtagctaca
    18661 agaatcgtta atttgatagc ttcattctct gatcatgtga taatccattc tcctgttgtt
    18721 tgtggtaata aatatcatta tattccccat cctttatata tttatcctat taagtctact
    18781 gaggatagtg cctgctcttt ttctaatgat aattattata tttttgggcg agttgtaaaa
    18841 tataaaaagt atgaagatgt tattagtgca ttccccgcca ataaaaatct aataattatg
    18901 ggatcatgtg aagatgatga atataaaata atgatacaag aactatgtaa aaatagaaaa
    18961 aatgttactt ttatgcctga atatatttca gacgaaaaag caaaggaatt actttctaca
    19021 ggtgctgctt taatcattag ccattctgat gaggatatga ttgtatccgg aagtttcttt
    19081 tacggtttga caattggtat taagatatta gcaataaata caccattttt aggttgggca
    19141 agttctgttt tacaaagaga cgtaatagag acctttgatg atttagattc tatgatgcat
    19201 catattaaaa ctgctcaaaa aggacaatca tcacgttatt catttcaatc aatagaggat
    19261 gttaataaat attttggtga tataagtatt gaatctaagt ttatgagttt attagatatt
    19321 aatgagaaga agtaatatgt tatgagaaac caataatgaa tttaattaat agcgcaaaat
    19381 gggttgcctt ttctcagttc ttcaaagtta ttgttcagtt agtaaatatt gtttatctgg
    19441 caagattaat accccctagt gaatatggta ttatggccat ggctttggtt gtaattaact
    19501 tcggactatt aataagagac ttgggtactg ccgctgcaat tatccaacgg aaagaaattg
    19561 atgatggtat tattaattcg attttctggt tgaatttatt tatggggctt tttattgctg
    19621 ttgctataat ttttgcctct ccattaatag caagcttttt tcataccccc aaactgattt
    19681 atgtattatt attgatttct ttaatatttc caatatctag tagttcagct gctcaccttg
    19741 ctcttttgga acgagcatcg aaattccgtg ttatttcctt gattgaaatt ttttcagcat
    19801 tgataggttt gatatctgca ttaattttgg cctatcaagg atatggtgtt tatagcctag
    19861 ttattcaaac gatcgtccta aatataattt caacgattct tttttggaaa atatctaaat
    19921 ggcgacctca gttgtctatg atgttcaaat tttcagggtt aaaacaaata gttggattta
    19981 gcgttaatct ttctttattt aattttgtta attatttttc aaggaataca gatagtttca
    20041 ttataggacg ctttatgcca tcttcagttc ttggtgcata cagcctcgcc tatagagtca
    20101 tgctttttcc tttacagagt cttacatttg ttgtatcgcg atcgcttttg ccaattttaa
    20161 gtcatcatca aaatgataat gcgattataa ggaaaaccta ctccaattgt gtattctcga
    20221 ttttatatct tgtagtaccg ttgatgagcg ggcttgctta tttaagttca ccttttgtat
    20281 ctgtaatttt tgggaatcaa tggaccttaa ctgcagaaat tttgaaatgg ttagcgccaa
    20341 ccgcaattat tcaagcagtg cttagtagta ctgggacagt tttcattgcc aagggccgca
    20401 ctgatttatt actcaaatta ggcattttgg gtacttttct atatgtcctc tcttttttaa
    20461 ttggtgttaa ttttgatatt atcacatttt ctaagttgta ttttatagct aatgtattaa
    20521 atttttttcc tgcaatgatt ctaatgatgc gattaatcga agggtcactc tttactttgc
    20581 ttaataaatg ttttgtaata ttttttatta atttcggaat gctggccttt ttatacttta
    20641 ttgatggttt ggatttcata aatgcaatta atgagcaagt tgtttattta atattaatga
    20701 tttctttagg tggagggttt tatgttttgt catctgtttt acttattggt aaattaagaa
    20761 ggttcctgtt ggcacgtttt gttaattaat actttcggta taatgttgag ttggatttgt
    20821 tgtgttctta ttaccaaggt atttgtatta aatttcattt atatgtctta catgaacgta
    20881 atctcctatg cgtgcttaca ttcttgagtt aggatataga gtgattttcg ttctaagtag
    20941 ttgtaaaaat ccttatattg ataggagaat gtaatgtcca agcaacagat cggggttgtc
    21001 ggtatggctg tgatggggcg taaccttgcg ctgaacatcg aaagccgtgg ttataccgtc
    21061 tccgttttca accgctcccg tgaaaagacc gaagaagtga ttgccgagaa tccaggcaag
    21121 aaactggttc cttactacac agtacaagag ttcgttgaat ccctcgaaac acctcgtcgt
    21181 atcctgttaa tggtgaaggc cggggctggc accgacagcg ccatcgattc cctgaagcct
    21241 tacctcgata aaggcgacat catcattgat ggcggcaata ccttcttcca ggacactatt
    21301 cgccgtaacc gtgaactatc tgccgaaggt ttcaatttta tcggcaccgg tgtctccggc
    21361 ggtgaagaag gggctctgaa aggcccttcc atcatgcctg gtgggcagaa agaagcctat
    21421 gagctggttg ctccaattct gaagcagatc gcggcggttg ctgaagacgg tgagccatgt
    21481 gtgacctata tcggtgctga tggtgctggc cattatgtga agatggttca taatggtatc
    21541 gagtatggtg acatgcaact gattgctgaa gcctatgcgc tgttgaaagg cggtctggca
    21601 ctttccaacg aagagttggc gcaaaccttc accgaatgga acgaaggcga gttaagcagc
    21661 tacctgatcg acattaccaa agatatcttc accaaaaagg atgaagaagg taaatacctc
    21721 gttgatgtca ttcttgatga agctgcaaac aaaggtacag gtaagtggac cagccagagc
    21781 tcactggatc tcggcgaacc tctgtctctg atcaccgagt ctgtatttgc tcgctatatt
    21841 tcttcgctta aagaccagcg tgttgccgcg tcgaaagtac tgagtggtcc gcaggcccag
    21901 ccggccggtg ataaagctga atttatcgaa aaagtgcgtc gcgcgttgta cctcggtaaa
    21961 atcgtttcct atgctcaggg cttatcccag ctgcgtgctg cttctgatga atacaactgg
    22021 gatcttaact acggcgaaat cgctaagatt ttccgcgctg gctgcatcat tcgtgcgcag
    22081 ttcctgcaaa agatcaccga tgcttatgcg caaaacgctg gcattgctaa cctcctgctg
    22141 gcgccgtact tcaaacagat cgctgatgac tatcagcaag cgctgcgtga tgtggtggct
    22201 tatgccgtgc agaatggtat tccggtaccg acgttctctg ccgcaattgc ctactatgat
    22261 agctaccgtt ccgcaattct gccggctaac ctgattcagg ctcagcgtga ttactttggc
    22321 gcgcatactt acaagcgtac cgataaggaa ggtgtattcc ataccgagtg gctggaataa
    22381 tttttcctgc agtcaggcca tttggcctga ctgtttaaat attcatacct aattttaaaa
    22441 aattaactaa attacttctt tcagcaaata atttaaatat tttattctca agcattttaa
    22501 gaatttgcca tatttattat cttgtgctcc tatattagtc tgcttctggc ctcagtaaat
    22561 tactgggtgt ttaataacag ggtttttaat taaaggaaat taatatgtta cttcctgtga
    22621 taatggctgg tggtaccggc agtcgtctct ggccgatgtc tcgcgagctt tacccgaaac
    22681 agttcctccg cctgttcggg cagaactcca tgctgcagga aaccatcacc cgactctcgg
    22741 gccttgaaat ccatgaaccg atggtcatct gtaacgaaga gcaccgcttc ctggtggccg
    22801 aacagctgcg ccagctcaac aagctgtcca acaacattat tcttgagccg gtcgggcgca
    22861 acaccgcccc ggccatcgcc ctggcggccc ttcaggccac ccgtcacggc gatgacccgc
    22921 tgatgctggt cctcgccgcc gaccatatca tcaataacca gccggtcttc cacgacgcca
    22981 tccgcgtcgc cgagcagtat gccgatgaag gccatctggt caccttcggt atcgtgccga
    23041 acgccccgga aaccggctac ggctacatcc agcgcggcgt ggccctcacc gacagcgccc
    23101 atactccgta ccaggtggcc cgcttcgtgg agaagccgga ccgcgagcgc gccgaggctt
    23161 acctcgcctc cggggagtac tactggaaca gcggcatgtt tatgttccgc gccaaaaaat
    23221 acctttccga gctggccaaa ttccgcccgg atatcctcga agcctgccag gccgcggtga
    23281 atgccgccga caacggcagc gacttcatca gcattccgca tgacattttc tgcgagtgcc
    23341 cggacgagtc cgtggactac gcggtgatgg agaaaaccgc cgacgcggtg gtggtcggtc
    23401 tcgatgccga ctggagcgac gtcggctcct ggtccgccct gtgggaggtc agcccgaaag
    23461 atgaacaggg taacgtcctc agcggcgacg cgtgggtgca caacagcgaa aactgctaca
    23521 tcaacagcga cgagaagctg gtggcggcca tcggtgtgga gaacctagtg attgtcagca
    23581 ccaaggacgc cgtgctggtg atgaaccgcg agcgttccca ggacgtgaag aaggcggttg
    23641 agttcctcaa gcagaaccag cgcagcgagt acaagcgcca ccgcgagatt taccgtccct
    23701 ggggccgctg cgacgtggtg gtccagaccc cgcgcttcaa cgtcaaccgc attacggtga
    23761 aaccgggcgg cgccttctcg atgcagatgc accaccaccg cgccgagcac tgggtcatcc
    23821 tcgccggcac cggccaggtg acggtcaatg gcaagcagtt cctgctgacc gagaaccagt
    23881 ccacctttat tccgattggc gccgagcaca gcctggaaaa cccgggccgt attccgctgg
    23941 aagtgctgga gatccagtcg gggtcgtacc tcggcgagga cgacattatt cgtattaaag
    24001 accagtatgg tcgttgctaa ttttattcgg gacaaacgta gaatgacaca gttaacatgc
    24061 tttaaggctt atgacatccg tggtgaactg ggcgaggagc tgaacgagga catcgcctac
    24121 cgtatcggtc gcgcctacgg cgaatttctg aaacccggga agatagtggt ggggggcgat
    24181 gtgcgcctca ccagcgagtc gctgaagctg gcgctggccc gcgggctgat ggacgccggc
    24241 accgacgtgc tggatatcgg cctgagcggc acggaagaga tttacttcgc caccttccac
    24301 ctcggggtgg acggcggtat cgaagtgacg gcgagccaca acccgatgaa ctacaacggc
    24361 atgaagctgg tgcgcgagaa cgcgaagccc atcagcggcg acaccggcct gcgggatatc
    24421 cagcgcctgg cggaggagaa ccagttcccg ccggtggacc cggcgcgtcg cgggaccctg
    24481 cgccagatat cggtgctgaa ggagtacgtc gaccacctga tgggctacgt ggacctggcg
    24541 aacttcaccc gtccgctgaa gctggtggtg aactccggca acggggcggc ggggcacgtg
    24601 attgatgaag tggagaaacg cttcgcggcg gccggggcgc cggtgacctt tatcaaggtg
    24661 catcaccagc cggacggcca tttcccgaac ggtatcccga acccgctgct gccggagtgc
    24721 cgccaggaca ccgccgacgc ggtgcgtgcg catcaggcgg acatggggat cgcctttgac
    24781 ggcgacttcg accgctgctt cctgttcgat gacgaggcgt cgtttatcga ggggtactac
    24841 attgtcggcc tgctggcgga ggcgttcctg cagaagcacc cgggggcgaa aatcattcac
    24901 gacccgcgtc tgacgtggaa cacggtggac atcgtgaccc gcagcggcgg ccagccggtg
    24961 atgtcgaaga ccgggcatgc gttcatcaag gagcggatgc gccaggaaga cgccatctac
    25021 ggcggggaga tgagtgcgca ccattacttc cgcgacttcg cctactgcga cagcgggatg
    25081 atcccgtggc tgctggtggc ggagctgctg tgtctgaaga acagttcgct gaaatcgctg
    25141 gtggcggacc gccaggcggc gttcccggcg tcgggggaga tcaaccgcaa gctggggaat
    25201 gcggcggagg cgatagcccg catccgggcg cagtatgagc cggcggccgc acacatcgac
    25261 acaacggacg gtatcagtat tgaataccct gagtggcgct ttaacctgcg cacgtccaat
    25321 accgagccgg tggtgcgtct gaacgttgag tccagagcgg atactgcgtt aatgaatgca
    25381 aaaaccgaag agattttagc tcttctcaag taatgcatta tccataatgg aagccatagg
    25441 gtcagatttt aatcgtattt ttgaccttat ggcttattct tgacatccca ctggtcaaag
    25501 cgtaaaaccg cgcacagcat tattaaaatt cgtggctagc cgccattacc cagttaactg
    25561 attaaagtgt aatcgaatga aaattactat ttccggtaca ggttatgttg gtttatcgaa
    25621 cggtatcctg attgcgcaaa accacgaagt ggtggccctg gatatcgtac aggccaaagt
    25681 ggatatgctt aaccagaaga tctctccgat tgtggataaa gagattcagg aatatctggc
    25741 agaaaaaccg ttaaatttcc gtgccaccac ggataagcac gacgcctatc gtaatgcgga
    25801 ctacgtgatc attgcgacgc cgaccgatta tgatcccaaa actaactact tcaacacctc
    25861 tacggtggaa gcggttattc gcgatgtcac agagatcaac ccgcgttcgg gttgatctc
//
