LOCUS       AB924566               25618 bp    DNA     linear   BCT 28-OCT-2015
DEFINITION  Klebsiella sp. 5758 DNA, capsular polysaccharide synthesis gene
            cluster, serotype: K28.
ACCESSION   AB924566
VERSION     AB924566.1
KEYWORDS    .
SOURCE      Klebsiella sp. 5758
  ORGANISM  Klebsiella sp. 5758
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella.
REFERENCE   1
  AUTHORS   Pan,Y.J., Lin,T.L., Chen,C.T., Chen,Y.Y., Hsieh,P.F., Hsu,C.R.,
            Wu,M.C. and Wang,J.T.
  TITLE     Genetic analysis of capsular polysaccharide synthesis gene clusters
            in 79 capsular types of Klebsiella spp
  JOURNAL   Sci Rep 5, 15573 (2015)
   PUBMED   26493302
  REMARK    DOI:10.1038/srep15573
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25618)
  AUTHORS   Pan,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2014) Contact:Yi-Jiun Pan National Taiwan
            University College of Medicine, Department of Microbiology; 1, Sec
            1, Jen-Ai Rd., Taipei 100, Taiwan
FEATURES             Location/Qualifiers
     source          1..25618
                     /organism="Klebsiella sp. 5758"
                     /mol_type="genomic DNA"
                     /strain="5758"
                     /serotype="K28"
                     /db_xref="taxon:1497805"
     gene            1676..2578
                     /gene="galF"
     CDS             1676..2578
                     /gene="galF"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose pyrophosphorylase"
                     /protein_id="BAT23512.1"
                     /translation="MKMNMANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVT
                     IMNVRQAQPLGLGHSILCARPVVGDNPFVVVLPDIILDGGTADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGR
                     YVLSADIWAELERTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQA
                     FVTYGMRNLKEGAKFRESIKKLLA"
     gene            2971..3600
                     /gene="cpsACP"
     CDS             2971..3600
                     /gene="cpsACP"
                     /note="orf2"
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase homologue"
                     /protein_id="BAT23513.1"
                     /translation="MNWQLISFFGDSTVLLPSAAALFIVLMLRKTSRLLAWQWSLLFG
                     ITGAIVCASKLAFMGWGLGIRELDYTGFSGHSALSAAFWPIFLWLLSARFSVGLRKAA
                     VITGYVLAAVVGYSRLVIHAHSFSEVIAGLLLGAAGSALFLVLQKRTPDPESVHISWG
                     GVACLVMVPLILLHSGSKAPTQSLLGQIATAVGPLDKPFTRTDLHKQAW"
     gene            4479..5993
                     /gene="wzi"
     CDS             4479..5993
                     /gene="wzi"
                     /codon_start=1
                     /transl_table=11
                     /product="surface assembly of capsule"
                     /protein_id="BAT23514.1"
                     /translation="MPRALSILVFPSFSLRYDSGAENGSCTMIKIARIAATLGLLSSL
                     GAQAYAAGLVVNDNDLRNDLAWLSDRGVIHLSLSTWPLSQEEIARALKKAKPSYSSEQ
                     VVLARINQRLSALKADFRVTGYTSTDQPGTPQGFGQTQPADNSLGLAFNNSGEWWDIH
                     LQGNVEGGERISNGSRFNANGAYGAVKFWNQWLSFGQVPQWWGPGYEGSLIRGDAMRP
                     MTGFLMQRAEQAAPETWWLRWVGPWQYQISASQMNQYTAVPHAKIIGGRFTFSPFQSL
                     ELGASRIMQWGGEGRPQSFSSFWDGFTGKDNTGTDNEPGNQLAGFDFKFKLEPTLGWP
                     VSFYGQMIGEDESGYLPSANMFLGGVEGHHGWGKDAVNWYVEAHDTRTNMSRTNYSYT
                     HHIYKDGYYQQGYPLGDAMGGDGQLIAGKIELITEDNERWSTRLVYAKVNPENQPINK
                     AFPHADTLKGVQLGWSGDVYQSVRLSTSLWYTNANNSDSDDFGASAGIEIPFSL"
     gene            6138..7277
                     /gene="wza"
     CDS             6138..7277
                     /gene="wza"
                     /codon_start=1
                     /transl_table=11
                     /product="putative capsule polysaccharide export protein"
                     /protein_id="BAT23515.1"
                     /translation="MKKKLVRFSALALAIGFLSGCTIIPGQGLNSLRKNVVELPDSDY
                     DLDKLVNVYPMTPGLIDQLRPETVLARPNPQLDNLLRSYEYRIGVGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNSDGTIFYPYIGKVQVAGKTLAQVRQDIASRLTTYIESPQ
                     VDVSIAAFRSQKAYVTGEVAKSGQQPITNIPLTVMDAINAAGGLSAEADWRNVVLTHN
                     GKDTKISLYALMQKGDLTQNHLLYPGDILFIPRNDDLKVFVMGEVGKQTTLKMDRSGM
                     TLAEALGNAEGMSQAFSDATGVFVIRQMKGDKKGKIANIYQLNAQDASAMVMGTEFYL
                     QPYDIVYVTSAPLVRWNRVISQLVPTITGVHDMTETVRYIKRWPN"
     gene            7277..7705
                     /gene="wzb"
     CDS             7277..7705
                     /gene="wzb"
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="BAT23516.1"
                     /translation="MFDSILVICTGNICRSPIAERILRKIFPNKKIDSAGVGAMVGYP
                     ADDSASHVANIYNISLQGHKAQQFTSNLARQYELILVMEKKHIEDVSRIAPEARGKTM
                     LLGQWLNKSIPDPYRKSDEVFNLVFKLIDEACQSWAKKLN"
     gene            7724..9868
                     /gene="wzc"
     CDS             7724..9868
                     /gene="wzc"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="BAT23517.1"
                     /translation="MTSLKNEKKIASENDDFDINRFIGEIIDHKKLIIAFTTGFTLIA
                     ILYAVLARPIYQANALLQIEQKQGNVLLNSLSQMLPDSQPQSAPEIALLQSRMILGKT
                     VDDLNLQAKVRREFFPLIGEGLARINGEEFGTIAISHIKYNNDDDKIPKIKITIINKE
                     QYKLEVADRVFKGKVNALLNTGDFDIVISSLKGTPGSVYNVTYMPHLKAIGMLQNALT
                     VADQGKDTGILNLTLLGDDPKQTSIILQTIVENYISQNIARQAAQDEKSLEFLNKQLP
                     IVRNDLDIAEDKLNSYRKMKDSVDLSMEAKSVLDQIVNVDNQLNELTFREAEISQLYT
                     KEHPTYKALLEKRNTLQEEKNKLNKKVSSMPSTQQEVLRLSRDVESGRPVYLQLLNRQ
                     QELNIAKSSAIGNARIIDNAVTDPKPVKPKKILIVLFGFVLGLGFSVFFVLLRVFMHR
                     GIESPEELEEIGVTVYASIPVSQWLMKKTNKKNNESNVLLATDNPADLAIEAIRGLRT
                     SLHFAMMESKNNILMISGASPSAGKTFISSNLASVIASTGKKILFIDADMRRGYVHKL
                     FNVTSEVGLSNILSGGCSIEQAIFHIENSGFDFIPRGIAPPNPAELLMSDKLEYVLKT
                     VSGKYDLIIIDTPPILAVTDAAIIGRYAGTSLLVARFEENTAKEIAVSIKKFIQSGIN
                     IKGCILNGIVKKASSRYGEGYNYYSYSYKGKD"
     gene            9901..10896
                     /gene="wckC"
     CDS             9901..10896
                     /gene="wckC"
                     /note="HG60; orf7"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23518.1"
                     /translation="MHGIIKQESVMEIMPKLVDVICPVYNKAELVVDFINSFIKFLDV
                     ENFNLIIVDDGSTDNLKEKIINIISPYENIYLLRKDNGGVSTARNYGFKYSSSKYVWF
                     CDPDDLIAKDSNYLLAELTKHNCDVYVFGYNIFDVQKRRITETFSFSSEKEVKSTDYL
                     INYDYFQNKNGISTIWNKIYNRNILEQVKFNELLSNAEDRVFNIEVLMLNVNCYLSTI
                     IIYQHNRYKDGTLSTTRNIKKIDDLRYANEFNIKALSKFKNVDFEKKKNVIIICSEML
                     SLGKFNMLKEYIYEHKRININIMPFISSKELIFFIPYASFFYNQLRRVYHKYKAP"
     gene            10937..11962
                     /gene="wcuC"
     CDS             10937..11962
                     /gene="wcuC"
                     /note="HG18; orf8"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAT23519.1"
                     /translation="MKGKIIKNCSYLILFITLFFFYQKNVFSLEIGVSTHIDSYSKEP
                     DYYINLVKEIGVTSIRNDYWWSQLEGEKKKFIVSSKLKKSTQLFNNLYDNNLSGLLVL
                     GYGNKLYNNGDYPRTEKDIDDFLDYISWVVIRFKGKVKYYEIWNEWYQGTSMEPFSKN
                     KPTDKQYLNLIKKVRDRIKDLDPAAIVLAGGFNPFDVKQNKWFSGLIDKGFLKYVDGV
                     AIHPYSYYRGSKFKSAYLNISEIDKFYNFYKNKGIDFQIYITEIGVPNGYLINSFSEQ
                     DSANFIREYIQLASKKQYIKGIWFYDLLDDGQNPFNYEHNFGLFKYDGSMKEVSALMR
                     KNNKSWR"
     gene            11967..13064
                     /gene="wckD"
     CDS             11967..13064
                     /gene="wckD"
                     /note="HG61; orf9"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23520.1"
                     /translation="MIKEVIILHDVDGRIYFDGIKQLLENGEIDEIKYYESIVIKRLL
                     KKVVSRNISASDIRTFKNNLLFRLKIPFIKNKTILLGMAPYNVRFVWYGLLARKNNVI
                     YHTSWPYWWTNNVPCKIPFFTNFLKNIFINYFKRFNFYYCGISKKSCESLGLHIANKN
                     RIYTIPHAVDLSIFKGSTALSLERKSIKIAFVGRMVKEKGIHDLITLVKRCDSYFEFT
                     FIGDGELLDLVKRELGEYKNVKITGRISDKNKIANLLSLSDVFILPSRKIEGWEELFG
                     ISLIEAMSAGLVVISTNHIGPTEIITNHVNGFIVNDDEKLVDNIYDLLKNMDFNSSCI
                     QEVKRQARLKANEYSIDSISRKWGDLFDSIK"
     gene            13175..14434
                     /gene="wzy"
     CDS             13175..14434
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAT23521.1"
                     /translation="MKTEKLFFNEPILHKKYIPIYISYIVCVFFSVFDGVRGVQFPSY
                     FPFSLMRDTSLFTLFILSLGFYKNIKFDKEFSIIFISQIFILFYTLFTSVLVSNHSVY
                     VRSNNVVLYQEYGAGVGVWMKMLTFIMLTYSTYCIAKVIKVSFLYKTMKWFVIAAFLY
                     SIITIIIYTVFPQIAIKLSHWGGRLSLGYPTEDVCFLALSLVFIYYINMPSIYKIIIV
                     LSNTLALFFQNTLTGFLLFAFVLFFYFLKGGVRLKFIVIVILVCIFVGAGVVYNNSEQ
                     FSDFGMLLHNKIDSILYFSSSENDPSFYLRMQQKELMLKSIFSDPIFFLFGYGGIGGM
                     AVESGLYSILGFAGTAGVIIYGVTLFYYIMRALVLKDMLLFCLVSMYCISSVSIAPLY
                     LMTTYWLFSFIIVYSSVYILKEQESNQ"
     gene            14452..15579
                     /gene="wclS"
     CDS             14452..15579
                     /gene="wclS"
                     /note="HG115; orf11"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAT23522.1"
                     /translation="MSMNTIKYHIAYSDLKSFFGNNPLFIFPTNTFGGHEVMTIGIIE
                     SLLISGCNVTVAIEPNNVSLKKKISQYDKLNNFILPLKQGRFEFLHALFNIYKIYKAN
                     RFLKKISQDGYSSIIIVQGDIELGSIYVNAAHTLNLPFISYIPYAHTAKKMGKKLSFL
                     RDLYYPFIYRRIKEYLTISDIFKDEIKAFSPSSNIYVLKNKVRDVSAFHERRKLHNSK
                     DNKKLYHIAVIGRVNFKQKGHDILLEAINRLSNESRKYIIVDIVGTGPDLKRLQSLVS
                     SSDLEKHFIFHGWQTEPWEKVYLDDALIIPSRFEGVPLVMLEGISIGMDILASNADGM
                     RDYLPENVLFNDSKELSILLEKKINQKLQKLKIAKGGNNNE"
     gene            15572..16561
                     /gene="wcuE"
     CDS             15572..16561
                     /gene="wcuE"
                     /note="HG20; orf12"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23523.1"
                     /translation="MNKIYIDSRWENYGGIGTFYSEINKINNYEDAKLRGKPMSPFDC
                     LSTTIQLFFRKNGVFFFPGYIPPVFLKNNYIFTIHDLNHLDRPENSSLIKRLFYRTIV
                     RRGCKKAKYVFTVSEFSRKKIIEWANISPEKVINVSNGVSHKFRPEGERSCYDFKYFL
                     CVSNRKGHKNEIGLLEAFKKARIDKNVKLVFTGKKNDFIANKIIELNLEDRIVFTGFV
                     HEDELPKIYRSAIGLVFVSFYEGFGLPVIEAQASGIPVITSNTTALCEIAGNGAILVN
                     PYNKNEISDAIEKIYNNDNNICELLIEAGYINCANYTWSKTAERVDFYINSIK"
     gene            16621..17898
                     /gene="wzx"
     CDS             16621..17898
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAT23524.1"
                     /translation="MKIFRFNKIALNAVWMMSEKIISIFGLIFVTSSVAKYVGPNLFG
                     QIALSLSIFQIVQIIAQMGGGTIIFKRLSKNLNSGVLLLNATLYMRVLLYFVISIPVL
                     VYYSYKSDYLSSIFIFATFISCFFSTLDVLAIYYDATLNSKINTCINVIGLFISLLLR
                     WFIVLLDWEPVYLSIPIILTGFIPFVIRICIFSSIKKRVIFSKRKKIQYVKYLFKSGY
                     NFVISDISVALYTRLSFFIISFFASKTEVGIYSVALALGNSWGFVNSSIISSFFTKIY
                     SLKNEADSLIISAKLNLLIFVIGLIITIGTLIFAPYFLLWFYGPLYSDAYIPLVILCM
                     STTVAGLGGVATRYIVRHSGYSFLSKKMFFTLITSVLLSVPLVYFYGIVGAAIATFLT
                     EFISLTLYNYFFKNRVIFDLHKSSVLFFLKVRT"
     gene            17953..19116
                     /gene="wbaZ"
     CDS             17953..19116
                     /gene="wbaZ"
                     /note="HG16; orf14"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23525.1"
                     /translation="MIPMEIKTKIALTADWLVSYAGAERVIKELIDLYPNLDLFSVVD
                     FLSDESRTHFQGKRATTTFIQRLPKAETSYQKYLPLMPVAIEQLDVSAYDIVLSSSHA
                     VAKGVLTGPDQMHISYVHSPIRYAWDLQHQYLREAKLDKGLKGIIAKYLLHKIRLWDY
                     RTANGVNHFIANSHFIARRIKKVYGRNADVIYPPVDVRRFILNENKEDYYVTASRLVP
                     YKRIDLIVDAFAAMPNKKLIVIGDGSEMSKIKSKATTNVEILGFQPNEIMRDYMKNAK
                     AFVFAAEEDFGITPVEAQACGTPVIAFGKGGSLETIRPYGVNKPTGVFFAEQTVPSLI
                     DAINLFENIFDKITPENCRENALRFSVDIFKDTFSKYIDEKWSEFNVAKKIQY"
     gene            19169..20560
                     /gene="wcaJ"
     CDS             19169..20560
                     /gene="wcaJ"
                     /note="HG10; orf15"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23526.1"
                     /translation="MTIHYQRANANASLISMVQRFSDIVLIFASLYAICLLNNVDFEI
                     RYLLFSLIVLVIFQMVGGITDFYRSWRGVKISAELKLILKNWFLSYVLALGIISLFHD
                     FDLNIRVAAIWFIVVTIGFVLCRSLIRVGAGILRRLGYNTRRVAVVGSLPAGINLLKS
                     FAEEPWMGFIVLGYYNSEPLTSVSDINFCGNFDKLIIDARDGKIDRIYIAMNMQEEAK
                     IKKIVQQLTDTTCSVLLIPDIFTFNILQARTEEINGVPVVPLFDTPLSGINMIFKRLE
                     DIIVSTVILLLISPVLLIISVAVKFSSPGPVLFRQLRYGMDGKPIRVWKFRSMRVMEN
                     DENVVQATKNDIRVTKVGKFLRSTSLDELPQFFNVWCGQMSVVGPRPHAVAHNEQYRA
                     LIQGYMLRHKVKPGITGLAQINGWRGETDTLEKMEKRIEYDLLYIRGWSIWLDLKIIF
                     LTVFKGFINKSAY"
     gene            20724..22130
                     /gene="gnd"
     CDS             20724..22130
                     /gene="gnd"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate-6-phosphate dehydrogenase"
                     /protein_id="BAT23527.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA
                     ENPGKKLVPYYTVQEFVESLETPRRILLMVKAGAGTDSAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVSPILKQIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLALSNEELAKT
                     FTEWNEGELSSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAQNAGIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRTDKEGVFHTEWLE"
     gene            22373..23788
                     /gene="manC"
     CDS             22373..23788
                     /gene="manC"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase"
                     /protein_id="BAT23528.1"
                     /translation="MLLPVIMAGGTGSRLWPMSRELYPKQFLRLFGQNSMLQETITRL
                     SGLEIHEPMVICNEEHRFLVAEQLRQLNKLSNNIILEPVGRNTAPAIALAALQATRHG
                     DDPLMLVLAADHIINNQPVFHDAIRVAEQYADEGHLVTFGIVPNAPETGYGYIQRGVA
                     LTDSAHTPYQVARFVEKPDRERAEAYLASGEYYWNSGMFMFRAKKYLSELAKFRPDIL
                     EACQAAVNAADNGSDFISIPHDIFCECPDESVDYAVMEKTADAVVVGLDADWSDVGSW
                     SALWEVSPKDGQGNVLSGDAWVHNSENCYINSDEKLVAAIGVENLVIVSTKDAVLVMN
                     RERSQDVKKAVEFLKQNQRSEYKRHREIYRPWGRCDVVVQTPRFNVNRITVKPGGAFS
                     MQMHHHRAEHWVILAGTGQVTVNGKQFLLTENQSTFIPIGAEHSLENPGRIPLEVLEI
                     QSGSYLGEDDIIRIKDQYGRC"
     gene            23775..25181
                     /gene="manB"
     CDS             23775..25181
                     /gene="manB"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="BAT23529.1"
                     /translation="MVVANFFGTKRRMTQLTCFKAYDIRGELGEELNEDIAYRIGRAY
                     GEFLKPGKIVVGGDVRLTSESLKLALARGLMDAGTDVLDIGLSGTEEIYFATFHLGVD
                     GGIEVTASHNPMNYNGMKLVRENAKPISGDTGLRDIQRLAEENQFPPVDPARRGTLRQ
                     ISVLKEYVDHLMGYVDLANFTRPLKLVVNSGNGAAGHVIDEVEKRFAAAGAPVTFIKV
                     HHQPDGHFPNGIPNPLLPECRQDTADAVRAHQADMGIAFDGDFDRCFLFDDEASFIEG
                     YYIVGLLAEAFLQKQPGAKIIHDPRLTWNTVDIVTRSGGQPVMSKTGHAFIKERMRQE
                     DAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELLCLKNSSLKSLVADRQAAFPASGEI
                     NRKLGNAAEAIARIRAQYEPAAAHIDTTDGISIEYPEWRFNLRTSNTEPVVRLNVESR
                     ADTALMNAKTEEILALLK"
BASE COUNT     7510 a   4933 c   5743 g   7432 t
ORIGIN
        1 acgtcataat actgctgacg ctgcgctgat taaggttcag cacccgctca atcatcagtc
       61 gttcctgcgg attaaacagt ggatgttgat cctgatcggc gaccagcgac gccgtgtcag
      121 catccagttc agctttttct ttctgcccgc tcagcaaatt catcaccgct tcggtagtgc
      181 gctgacgcag cgtcatattg gcggagagga agcgacggcg gttaaactgc gccaactggt
      241 taagcgcttc aatcatgacc gagaagccaa tggccgcata taaatagcct ttcggaatga
      301 taaagctgaa gccttcagca atcaggctga agccgatcat cagcaggaag ctcagacaga
      361 ggatcacgat ggtcgggtgg ctgttaacga agcgcgtcag cgccttgctg gccatcagca
      421 tcaggctgat ggcgataacc acggcggcca tcatcaccgc caggtgatca accatgccga
      481 cggcggtgat caccgagtcg agtgagaaga tggcgtcgag caccacgatc tgcgccacga
      541 cggcccagaa tttcgcccct ttgcgctggg tggggttatc gctgtctttc ccctccagcc
      601 gctcattaag ctcgacggtc gctttaaaca gcagaaacag gccgccaaac agcataatca
      661 aatcgcgggc gctaaagctg aagtcgtgaa aaacaatcag cggtttggtc agggtgacca
      721 gccaggagat agaggccagc agcagaagac gcatgcccat cgccagcatc aggccagtga
      781 tccgcgcgcg gtcgcgctgg gcgggaggga gcttctcggc gaggatagcg ataaagacca
      841 ggttatcgat acccaacacc agttcgataa ctaccagcgt gacgagacct gcccagattg
      901 acggatcggc aatccattcc atatgtatta aaacctgtac gactgcggta tgtgttacca
      961 cgatcatgga taagatgagt ctaaaatgca ataacgacgc ggatatcgcc ctgccgtggg
     1021 tggatatatt tccagcggat taagcgaacc gataagaatt atgttccgga aaagaacagt
     1081 gaaaaaataa caccatggcg gcgaccatgg aataagcttg ccgatatcag aactttttcc
     1141 gctgcgtttc agcgagggcg gcaaaagggc ttcctcccgc ggttcgtcac ggcgagcgcg
     1201 gatgcgcaga gcagaagcga agcgcgaagc ccgctcacaa aaccggcata attcatatta
     1261 tgaagtgagt gcagaatagg gcggatcgca gttcaccgtc gcggattcag gctaatatgt
     1321 cgtcatatcc ggctgtttat gctgaaatat attgcctggc gaaatttatt atctctatct
     1381 attctttcca ggcatacgcg cggcgcggcg gggccggcgg ccaacagacc ccgatagacg
     1441 ggcctctcag ccacatcgcg cggcgcaaag gaacgagccg ctgaataacc tgaacgaaaa
     1501 taagattatt ctcacttctg actgttggta aaagggagtt gtgtgtattc ttttacgtga
     1561 cagtgaattt aagaatttgg cgggcagatg cccgggcagt atccgtgtat tatcagttcc
     1621 aatggatttg tgacatgtac aattttgcaa aaccgcgtgt tttgcaacca aacaggtgaa
     1681 gatgaatatg gcgaatttga aagcggttat tccggtcgca ggactaggca tgcatatgct
     1741 gccggccaca aaggcaattc caaaggagat gctgccgatc gttgataagc caatgattca
     1801 gtacatcgtt gacgaaatcg tcgccgccgg gatcaaagag attgttctgg tgacgcactc
     1861 ctcgaagaac gcggtggaaa accacttcga cacatcctac gagctggaag ccctgctgga
     1921 acagcgcgtg aagcgccagc tgctggcgga agtgcaggcc atttgcccgc cgggcgtgac
     1981 catcatgaac gtgcgtcagg cgcagccgct gggcctgggc cactccatcc tctgcgcccg
     2041 cccggtagtc ggcgacaacc catttgtggt ggtcctgccg gatatcatcc ttgacggcgg
     2101 caccgctgac ccgctgcgct ataacctcgc cgctatgatc gcccgcttta acgagaccgg
     2161 ccgcagccag gtgctggcga aacgcatgcc gggcgatctt tccgaatact ccgtcatcca
     2221 gaccaaagag ccgatggtgg ctgaaggcca ggtggcgcgt atcgtcgagt ttattgaaaa
     2281 accggacgag ccgcagactc tggactccga tctgatggcg gtggggcgct acgtgctgtc
     2341 ggcggatatc tgggccgaac tggaacgtac cgagccgggc gcatggggcc gtatccagct
     2401 gaccgacgct attgccgaac tggcgaagaa gcagtccgtc gacgcgatgc tgatgaccgg
     2461 cgaaagctac gactgcggga agaaaatggg ctacatgcag gccttcgtca cctacgggat
     2521 gcgtaacctg aaagaaggcg ccaaattccg cgaaagcatt aaaaaactgc tggcctgagc
     2581 gccagcctga aaccgagcgg caaggctgaa gcattcgtcc tgccgctcat aacgttatgc
     2641 agaaattatt cataacgcga atgttataac gattgtaaag aaacgtatgg cttcggagac
     2701 ttctggtagt ttgtctctgg cctctgtggt gcaatggtcg gagtagcggc aataatgctt
     2761 tatgaatagt cacttagtgc gacaattcct atagcgcagg aaaagcggtc aacgacagcc
     2821 aaaaataaaa cttgactgcg atcatgtttc cgctttaaac atctcacttg catgcataaa
     2881 aatgtgaaat gaattggcat gcgagctggt acagacatta cggataatcc ctgagcacgg
     2941 cagtggacat catcgaagga tcacaggtat atgaactggc aactcatctc attttttggc
     3001 gatagcaccg ttttgctgcc cagcgcagcg gcgctgttta ttgtcctgat gctgcgtaaa
     3061 acgtcgcggt tgctggcgtg gcagtggagt ttgctgttcg gcatcaccgg cgctatcgtc
     3121 tgcgcctcca aactggcctt tatgggctgg ggtctgggta ttcgtgagct ggattacacc
     3181 ggcttcagcg gccactccgc gctctccgcg gccttctggc ctatcttcct gtggctgctc
     3241 agcgcccgtt tctccgtcgg tctgcgtaaa gcggccgtta ttaccggcta tgttctggcc
     3301 gccgtggtgg gctattcgcg gctggtcatc catgcgcatt ccttctcgga agtgattgcc
     3361 ggcctgctgc tgggcgctgc tggcagcgct ttgttcctgg tgttgcaaaa acgtacccct
     3421 gatccggaaa gcgtgcatat ctcatggggc ggtgttgcat gcctggtgat ggttccgctt
     3481 atccttttac atagcggcag caaagcgccg actcagtccc tgctgggaca aattgccacc
     3541 gcggtggggc cgctggataa accctttacg cgtaccgatc tgcacaagca ggcctggtaa
     3601 tcgccatttg ttttacaggg gaaattaagt tttcgccggt taattagaca aataagaaaa
     3661 taatctacta tatacccggt aattgataat tcatatttat gaaataatga agtgctacta
     3721 cattgttatt gcatatttgc ctggatatag ccttgatcag acgtttctta aatgcgctga
     3781 gacgttacct gatggacatt caatgaatat ccagctacag gaaactatta gaaattgtag
     3841 ttgactacaa tgccatcatc tgatttttgc atgttgatga gctatggaaa aagacgtttt
     3901 tttacagtca gttagctgca tatgtgatgt tgtagcagta ccgggaagat ctttaaccct
     3961 ggaagccagt gaataatctt aattggtgac ccgcttattt tttgtcagta gaacgacagg
     4021 cggcattaat tggcagatat tcggtaacaa cactcccaat tgtgaccgaa atcccgtaaa
     4081 cttaacgccg ccaaaaataa tggcctgacc aattattcat ccacgggtcg ataaaaatta
     4141 agtcgttcag gtagtcagtg cgctggtagc tgttaagcca ggggcggtag cgtcgctgaa
     4201 gccgcttgct gctgcacaga ggttctcttc aacggctgta aatatcgacc cggtgaggat
     4261 gatcatcatc aatagatatc tatcaatttt ctatggatat cctcagtagt tggccaggag
     4321 cggctgctga tatcgcctgg agattaactt tcctgtctca tccatagcct gtagggtaaa
     4381 attcgcctac attgtgagct gagtggatgt tataaggcta acaagcagct tagggtaaat
     4441 gtacttgcct cgccggtgtt gcacagcgaa gtcagctggt gccgcgagcg ctttctatct
     4501 tggtattccc ctcattctca ttgagatacg acagcggggc tgaaaatgga tcttgtacaa
     4561 tgataaaaat tgcgcgcatt gccgcgacgt tgggtttgct ttcctccctg ggagcccagg
     4621 cttacgcggc cgggttagtg gtaaatgaca acgacttgcg taacgacctg gcctggcttt
     4681 ccgatcgcgg ggtcatccat ctgagcctgt cgacctggcc gctgagccag gaagagatcg
     4741 cccgggcgct gaaaaaggcc aaaccttcct actcttctga gcaagtggtg ctggcgcgta
     4801 tcaaccagcg actgtctgcc ttaaaggcgg atttccgggt caccggctac acttcaaccg
     4861 atcagccggg cactccgcag gggtttggtc agacacagcc ggcggataac tcgttaggcc
     4921 tggcattcaa caacagcggc gagtggtggg atatccatct ccagggcaac gttgaagggg
     4981 gagagcggat cagcaacgga tcgcgcttca acgccaacgg cgcatacggc gcggtgaagt
     5041 tctggaacca gtggctctct tttggccagg taccacagtg gtgggggcct ggctatgaag
     5101 gtagcctgat tcgcggggat gccatgcgac cgatgaccgg tttcctgatg cagcgagccg
     5161 agcaggcggc gccagagacc tggtggctgc gctgggtggg gccatggcag taccagatct
     5221 ccgccagcca gatgaatcaa tataccgcgg tacctcatgc caaaattatc ggcggacgtt
     5281 ttaccttttc accattccag tcattagaat taggcgcgtc gcgcattatg cagtggggcg
     5341 gggaaggccg accacaatca tttagcagtt tctgggatgg ctttaccggg aaagacaata
     5401 ctgggacaga taacgaacct ggtaaccagc tagctggttt tgactttaag tttaaactcg
     5461 agccaactct cggctggccg gtcagtttct acggacagat gattggcgaa gatgagtcag
     5521 gatatctgcc ttcggcaaat atgttccttg gtggagtgga agggcaccac ggttggggta
     5581 aagatgcggt aaactggtac gtggaagcgc atgatactcg taccaatatg agccggacga
     5641 attacagcta tacccaccac atctataaag atggttatta ccaacaaggg tatccactgg
     5701 gcgatgcgat gggtggggat ggtcaactca ttgccggtaa gattgaactt attacagaag
     5761 ataacgagcg ctggagtacg cgcctggttt acgccaaagt taacccggag aatcagccga
     5821 tcaataaagc attccctcat gctgatactt tgaaaggtgt acagctcggt tggagcgggg
     5881 atgtgtatca gtcggtacgt ttgagtacat cactgtggta caccaacgcg aacaacagcg
     5941 acagcgacga ctttggggcc agcgcaggga tagaaatacc atttagttta taaggctgaa
     6001 tgctgaaaac agggagagag ggtggtagcg ctgcaggacg cagtcagttt taatctctcc
     6061 acaagccggc aggtaagcaa cggcgatgac agctgctcag gaattggcaa attttgattt
     6121 actgatgatg tgacattatg aagaaaaaac ttgttagatt ttcggcatta gcattggcaa
     6181 ttgggttttt atcgggttgt acaatcatcc ctggtcaggg attaaacagt ctgcgtaaga
     6241 acgtggttga gcttccggat agtgattacg atctggataa gttggtgaat gtatacccga
     6301 tgacaccagg gttgattgat caacttcgcc ctgaaaccgt tctggctcgt cccaatccgc
     6361 aacttgataa cttactccgt agttatgaat atcgcattgg ggtaggtgac gtactgatgg
     6421 ttaccgtatg ggaccaccct gaactaacta ctcctgctgg tcaataccgc agcgccagcg
     6481 acaccggtaa ctgggtcaac tccgatggca ccattttcta tccttatatc ggtaaggtgc
     6541 aggtagcggg gaaaactctc gctcaggtac gccaggatat agccagtcgt ttaactacgt
     6601 atattgaaag ccctcaggtt gatgtaagta ttgctgcatt tcgatcgcag aaagcttatg
     6661 taacaggaga agttgctaaa tccggacaac agcctatcac taatattcct ctcacagtaa
     6721 tggatgcgat taatgctgca ggaggattat cagcggaagc tgactggcga aatgtagtat
     6781 taacacataa tggtaaagat acaaaaatat cgctttatgc tctaatgcag aaaggggatt
     6841 taacgcagaa tcatctctta tatccgggag atattttatt tataccacgt aatgatgatc
     6901 taaaagtttt tgttatgggg gaagttggca aacaaacaac tcttaagatg gaccgtagtg
     6961 ggatgacatt agcagaagca ttaggtaatg cggaaggtat gtcacaagcg ttcagtgatg
     7021 ctacaggtgt atttgtgata cggcaaatga aaggtgacaa aaagggaaaa attgcaaata
     7081 tatatcaact taatgcgcaa gatgcctctg caatggtcat gggaactgag ttttatcttc
     7141 agccttatga tattgtttat gttacttctg ctcctttagt gcgttggaat cgtgttattt
     7201 cgcaacttgt gccaacgatt actggtgttc atgatatgac tgaaactgta cgttacataa
     7261 agagatggcc taattaatgt ttgattcaat attagtaatt tgtactggaa atatatgccg
     7321 ttcccccatc gcagagcgta tattgagaaa gatattcccc aataagaaga ttgactctgc
     7381 aggagtagga gcaatggttg gatatcctgc ggatgactca gcatctcatg tcgctaatat
     7441 atataatatt tcattacagg ggcataaagc acagcaattt acatcaaatt tagcccggca
     7501 gtatgagtta atactggtaa tggagaaaaa acatatagaa gatgtcagtc gcatagctcc
     7561 tgaagccaga ggtaaaacaa tgttgctagg ccaatggtta aataaaagta taccagatcc
     7621 ctatagaaaa agtgacgaag tttttaatct ggtatttaag ctgatagatg aggcatgcca
     7681 aagttgggct aagaagttga actgacaaac tcaggataaa agaatgacat ctttaaaaaa
     7741 cgaaaaaaaa atagcttcag aaaatgatga ttttgatata aatcgtttta ttggagagat
     7801 tatagatcat aaaaaattga taatagcgtt cacaacagga tttacgctga ttgcgatttt
     7861 atatgcggta cttgcgaggc caatatacca agctaacgct ttactgcaga ttgaacaaaa
     7921 gcaagggaac gtattattaa atagtctgtc ccagatgctt ccagacagcc aaccgcaatc
     7981 agcacctgag atagcattac tgcaatcaag aatgatcttg ggaaaaactg tagatgattt
     8041 gaatctacag gccaaagtga gacgtgaatt ttttccatta attggggagg gattagctcg
     8101 aataaatggt gaagagtttg gaactatagc tataagtcat attaaataca ataatgatga
     8161 tgacaaaata ccaaaaatta aaataacgat tataaataaa gaacagtata aattagaagt
     8221 ggctgaccga gtctttaaag gtaaagtgaa tgccttacta aataccggag attttgatat
     8281 tgttatatct tcactaaaag ggactccagg atctgtatat aatgttactt acatgcccca
     8341 tttaaaagct attgggatgt tgcaaaatgc attaactgta gcagaccaag gtaaggatac
     8401 gggtatactt aatttgacat tgcttggtga cgatcctaag caaacttcaa tcattttaca
     8461 gacaattgtc gaaaattaca tatcacaaaa tatagcacgg caagcagcgc aagatgaaaa
     8521 aagtttggaa tttcttaata aacaattgcc aatagttagg aatgatcttg atattgctga
     8581 agataaactg aattcgtata ggaaaatgaa agattcagtg gatctttcaa tggaagccaa
     8641 atcagtttta gaccaaattg taaatgttga taatcagcta aatgaattaa cattcaggga
     8701 ggctgaaata tctcagttgt atacaaaaga gcacccaaca tataaagcat tattagaaaa
     8761 aaggaatact cttcaagagg aaaaaaataa gttaaacaaa aaagttagtt ctatgccatc
     8821 gactcaacaa gaagtattaa ggttaagtag agatgttgaa tcaggaaggc cagtttattt
     8881 acaactactt aatcgacagc aagaactgaa tattgcaaag tctagtgcaa taggaaatgc
     8941 cagaattatt gataatgctg taacagatcc taaaccggtt aagccaaaga aaattttgat
     9001 tgtactgttt ggctttgtat tagggcttgg cttttctgtt ttcttcgtat tactacgtgt
     9061 tttcatgcac cgtggaatag aatctccaga agagttagaa gaaattggtg ttactgttta
     9121 tgcaagtatc cctgtatccc aatggctaat gaagaaaaca aataagaaaa ataatgaatc
     9181 caatgtatta ttagcaacag acaatccggc ggatttagct attgaagcta tccgaggcct
     9241 gagaactagt ttacactttg caatgatgga atcaaagaat aatattctta tgatttctgg
     9301 tgcaagtccg agtgccggga agacctttat tagtagtaac cttgcttcgg taatagcatc
     9361 taccgggaaa aaaatattat tcatagatgc tgatatgaga agaggttatg tccataaatt
     9421 atttaacgtc acttctgagg tagggctttc aaatatatta agtggtggct gttctataga
     9481 acaagctatt tttcatattg aaaacagcgg ctttgacttt atacctagag gtatcgcccc
     9541 accaaatcct gctgaattat taatgagcga taaattagag tatgtcttaa aaacggtttc
     9601 gggaaaatat gatttaataa ttattgatac accacctatt ttggctgtta cggacgcagc
     9661 tataatagga agatatgcag gaacatcgct attagttgca aggttcgaag aaaatacggc
     9721 aaaagaaatt gctgtgagca ttaaaaagtt tattcaaagt ggtataaata taaaaggatg
     9781 tattttgaac ggcattgtta aaaaagctag tagccgttat ggagaggggt acaattatta
     9841 ctcatattca tataaaggga aagactaatt tattatagcc atgcgttaga taaatatcta
     9901 atgcatggca ttataaagca ggaaagtgtt atggaaatta tgccgaagtt agtagacgtt
     9961 atctgtcctg tttataataa ggctgaactt gttgtagatt ttataaattc atttataaaa
    10021 tttcttgatg ttgaaaattt taacttgata attgttgatg atgggtctac tgataattta
    10081 aaagaaaaaa ttattaatat tataagtcct tatgaaaata tatatctctt acgcaaagat
    10141 aatggtggag tttcaacagc taggaattat ggctttaaat actcaagttc aaagtatgtc
    10201 tggttttgtg acccagatga tttaattgct aaagatagta attatttact agctgaatta
    10261 actaaacata attgcgatgt atatgtgttc ggatacaaca tatttgatgt acaaaaaaga
    10321 agaataacag agacattctc attttcaagt gaaaaagaag ttaaaagcac tgattattta
    10381 attaattacg attattttca aaacaaaaat gggataagta ctatttggaa taaaatatat
    10441 aataggaaca tattagagca agtaaaattt aatgagttat tatctaatgc ggaagatcgt
    10501 gtatttaaca ttgaagttct aatgttaaat gttaattgct atctttcaac gataattatt
    10561 tatcaacata atcgctataa agacggtaca ttaagtacca caagaaatat aaaaaaaatt
    10621 gatgatctta gatatgcaaa tgaatttaat attaaagcat tgagtaaatt caaaaatgtt
    10681 gatttcgaaa agaaaaaaaa cgttattata atttgctcag aaatgttatc tttgggcaaa
    10741 tttaacatgc ttaaggaata tatatatgag cacaaaagaa taaacatcaa tataatgcct
    10801 tttatatcat caaaagaatt gatatttttt atcccatatg ctagtttttt ttataatcaa
    10861 ttaagaagag tttatcataa atataaagcg ccatgataag aaatttaata aaacatatag
    10921 aatagggctt accgaaatga aagggaagat tataaagaac tgctcctact taatattatt
    10981 tattacatta ttttttttct atcaaaaaaa tgtgttctca ttagaaatag gagtgagtac
    11041 tcatatagat agttattcta aagaaccaga ttattacatt aatttggtaa aagaaattgg
    11101 tgttacttcg atccgaaatg attattggtg gtcgcaattg gaaggtgaga aaaaaaaatt
    11161 tattgtctct tcaaagctga aaaaatcgac acaattattt aataatcttt atgacaataa
    11221 tttatcaggt ctgctggtat taggctatgg aaacaaattg tacaacaacg gtgactatcc
    11281 aaggacagaa aaagatatag acgattttct tgattatatt tcttgggttg taatccggtt
    11341 taaagggaaa gtaaagtatt acgaaatttg gaatgaatgg tatcaaggta ctagcatgga
    11401 gcctttttct aagaataaac ctactgataa gcaatatctt aatttaataa aaaaagttag
    11461 ggatagaata aaagatctgg atcctgcggc aatcgtgctt gccgggggtt ttaatccatt
    11521 tgatgtcaaa caaaataaat ggttttcggg attaatagat aaaggatttt taaaatatgt
    11581 tgatggtgta gctatacacc catattctta ctacagaggc tctaaattta agtctgccta
    11641 tttaaatatt agtgagattg ataagtttta taatttttat aaaaataaag ggattgactt
    11701 tcaaatatat ataacagaaa ttggagtgcc taatgggtat ttaataaact cattttcgga
    11761 gcaagattcc gcaaatttta ttagagaata tatacaacta gcaagtaaaa aacaatatat
    11821 aaaaggaatt tggttttatg atttactaga tgatggacag aacccattca attacgaaca
    11881 taattttggg ttgtttaaat atgatggttc tatgaaagaa gttagtgcgt taatgagaaa
    11941 gaataataaa tcatggagat aagttaatga ttaaagaagt aataatatta catgatgtag
    12001 acggacggat ctactttgat ggtattaaac agctactcga aaatggagaa atcgatgaga
    12061 taaaatatta tgaaagtatt gtaattaaac gactcttaaa aaaagtagtg agccgtaaca
    12121 tctcagctag tgatattaga acttttaaaa ataatttatt gttccgctta aaaattcctt
    12181 tcattaagaa taaaaccata ttgttaggaa tggcaccata taatgttagg ttcgtatggt
    12241 acggtttatt ggctagaaaa aataatgtaa tatatcatac ttcatggcct tattggtgga
    12301 ctaataatgt gccttgtaaa atcccatttt tcactaattt tttgaagaat atatttataa
    12361 attattttaa gcgattcaac ttttattatt gtggcatttc taaaaaatca tgtgaatcat
    12421 taggcttaca tatagctaat aaaaatcgaa tttatacgat ccctcatgct gtagatttgt
    12481 ctattttcaa aggtagtaca gctttaagtc tcgaaaggaa atctattaag atagcttttg
    12541 tcggaagaat ggttaaggaa aaagggatcc atgaccttat cactttggtt aaaaggtgtg
    12601 attcatattt tgagtttaca tttattggtg acggtgaatt attagatctc gttaaaagag
    12661 agttgggtga atataaaaat gttaaaataa caggaagaat tagtgataaa aataaaattg
    12721 ctaatttact ctcattatca gacgtcttta tacttccttc cagaaaaatt gaagggtggg
    12781 aggaactctt tggtatttct ttaatagaag caatgtctgc cggactagta gtaatatcta
    12841 ccaatcatat cggcccaaca gagattataa ctaatcatgt taatggtttc attgttaatg
    12901 atgatgagaa acttgtagat aatatttatg atttacttaa aaatatggac tttaattctt
    12961 cttgtatcca ggaagttaaa agacaggcaa gattaaaggc taatgaatat tctatagata
    13021 gcatatcgcg taaatggggt gatttatttg attctattaa atgatgaact tcattagata
    13081 ttcatttctt ataaaggcat cattaaaaga agagtcagaa catgaaccga ataattttat
    13141 gtacgcaagc aattaaatta agtgtataga aataatgaaa acagaaaaat tgttctttaa
    13201 cgaaccgata ctgcataaaa aatatattcc tatttatatt tcatatattg tttgtgtgtt
    13261 tttttccgtt tttgatggcg ttagaggtgt acaatttcct tcgtattttc cattctcgct
    13321 catgcgtgac acttcgttat ttacattatt tattttatca ctaggttttt ataaaaatat
    13381 taaatttgat aaagagtttt caataatctt tattagtcaa atttttatac tcttctatac
    13441 attgtttact agtgttctag tttcaaatca tagcgtttat gtgcgaagta ataatgtcgt
    13501 attgtatcaa gagtatggcg ctggtgttgg tgtatggatg aaaatgctga catttataat
    13561 gttaacatat tcaacttatt gtattgcaaa agttattaaa gtatcatttt tatataaaac
    13621 catgaaatgg tttgtaattg ctgctttttt atattcaatt attaccataa ttatatatac
    13681 agtattccca caaattgcta ttaagctatc gcattgggga gggcgtcttt ccttaggtta
    13741 tcctacggaa gatgtatgtt tcttggcatt atcgcttgta tttatatatt atataaacat
    13801 gccttccatt tataaaatta ttatagtttt atccaatacg ttagccttat tttttcaaaa
    13861 tacattaact ggatttttac tttttgcctt tgtattattt ttttattttt taaagggggg
    13921 ggtgcgttta aaatttattg tcattgttat tcttgtttgt atatttgttg gtgctggtgt
    13981 tgtttataat aatagtgagc aattttctga tttcggaatg ctgttgcata ataagataga
    14041 ttctatatta tatttcagtt cgtccgagaa tgatccttcc ttttatttaa gaatgcagca
    14101 aaaggaattg atgcttaaat ctattttctc tgatcctata tttttcttat ttggttatgg
    14161 tggtatcggt ggaatggccg tagaaagcgg attatattct attttgggtt ttgctggtac
    14221 tgctggtgta attatatacg gtgttacatt attttattat ataatgcgag cattggtgtt
    14281 aaaagatatg ttgttgtttt gtctcgtatc gatgtactgc atatcatctg tttcaattgc
    14341 accactttat ttaatgacaa catattggtt attttctttt attattgtat atagtagtgt
    14401 ttatatactc aaagaacaag agtcgaatca atagctcaag gttatttttc catgtctatg
    14461 aatactatta aatatcacat tgcttattct gatttaaagt ccttttttgg taataaccca
    14521 ctatttatat tccctacaaa tacatttggc gggcatgaag taatgaccat tggtattatt
    14581 gagtctttac ttataagtgg atgtaatgta actgttgcta ttgaacctaa taatgtctcg
    14641 ctaaagaaaa aaatatcaca atatgacaag ttaaataatt ttattttacc tttaaaacaa
    14701 gggcgatttg agtttttaca cgcactgttt aatatatata agatatataa agcaaatcgt
    14761 tttttaaaaa aaataagtca agatggctat agttcaataa taattgttca aggagatatt
    14821 gaattaggtt caatatatgt aaatgccgcc catacgttaa atttgccttt tatttcttat
    14881 attccatatg cccacacagc taagaaaatg ggcaagaaac tttctttctt aagagactta
    14941 tattatccat ttatttatag gcgtataaaa gaatacttaa caataagtga catttttaaa
    15001 gatgaaatta aagctttttc cccatcgagc aatatctatg ttttaaaaaa taaagtaaga
    15061 gatgtttctg cttttcatga acgaaggaaa ttgcacaatt ctaaagataa taagaaatta
    15121 taccacattg ctgttattgg acgagtgaat tttaaacaaa aaggccacga tatattactt
    15181 gaagcaataa atcgtttatc aaacgaatct cgtaaataca ttattgtaga tattgtcggc
    15241 actggtcctg atttaaagag attacaaagt ttagtgtcat caagtgattt agaaaaacat
    15301 tttatattcc atggctggca aacagaacct tgggaaaaag tttatctgga tgatgcatta
    15361 attattcctt ctcgttttga aggtgtacca ttggttatgt tagaggggat aagtattggc
    15421 atggatattc ttgcatctaa cgccgatggt atgcgtgact atctccctga aaacgttctg
    15481 tttaacgact caaaagaatt atctattttg cttgagaaaa aaatcaatca aaaacttcaa
    15541 aaattgaaaa tcgctaaagg gggaaataat aatgaataag atttacattg attctcgttg
    15601 ggaaaattat ggcggcatcg ggacgtttta ttctgaaatt aacaaaatta ataattatga
    15661 agatgctaaa ctacgtggta agcctatgtc accctttgac tgcttaagca ctacgattca
    15721 actttttttt agaaagaatg gagttttctt ttttcccgga tatatacctc ctgttttttt
    15781 aaaaaataat tatatattca ctatacatga tctaaatcat ttggatagac ctgagaactc
    15841 tagtttaatc aagcggttgt tttatagaac aattgttaga agaggatgta aaaaagcaaa
    15901 gtatgttttt acagtctccg agttttctag aaaaaaaatt atagagtggg ctaacatttc
    15961 tcctgaaaaa gtgattaatg ttagcaatgg cgtttctcat aaatttcgcc ctgaaggaga
    16021 aaggtcttgt tatgatttca agtatttttt atgtgttagc aatcgtaagg ggcataaaaa
    16081 tgaaataggc ctattagaag cgtttaaaaa agctagaatt gataagaatg taaaattagt
    16141 ttttactggt aaaaagaatg attttattgc taataaaatt attgaattaa atttagagga
    16201 tcgaatcgtt ttcacaggtt ttgttcatga agatgaatta cctaaaattt accgttctgc
    16261 aatcggttta gtatttgttt ctttttacga aggttttggg cttccagtga ttgaggcaca
    16321 agctagcggt atccccgtta taacatctaa tacaaccgca ttgtgcgaaa ttgcagggaa
    16381 tggagctatt ttagttaatc catataataa gaatgaaatt tctgacgcta tagagaaaat
    16441 atataataat gataataata tttgtgagtt attaatagag gcgggatata ttaactgtgc
    16501 taattataca tggtcaaaaa ctgctgaacg agtagatttt tatattaatt ctataaaata
    16561 attaaaatta tattttttaa attataatga aaatggtaat gtttctcact aggtcatttt
    16621 atgaaaattt tccgatttaa taaaatcgca ctcaacgctg tttggatgat gtctgagaaa
    16681 attatttcta tttttggact gatttttgtc acatcttccg tagctaagta tgttggcccg
    16741 aatctttttg gacaaattgc tctatcttta tcgattttcc aaatcgtgca aattatcgca
    16801 caaatggggg gggggacaat aatatttaaa agattatcaa agaatttaaa ctcaggggtt
    16861 ttacttttaa atgcaactct ctatatgcgc gttctgctat attttgttat ttcaattcct
    16921 gttttagttt actactccta taaaagcgat tatctcagtt caatttttat ttttgctaca
    16981 ttcatatcat gttttttttc tactttagac gtgctggcta tatattatga tgcaactttg
    17041 aattccaaaa ttaacacatg tattaacgtt atagggctat ttataagttt actgcttaga
    17101 tggtttatcg ttttactcga ctgggagcct gtatatctat ctattcccat aatcctgact
    17161 gggttcatac cttttgtaat tagaatatgc atttttagtt ccataaagaa aagagtgatt
    17221 ttttctaaac ggaaaaaaat tcaatacgtg aagtatttat tcaagtcagg gtataatttt
    17281 gttatttctg atatttcagt tgctttatat acaagactat ccttctttat tatctcattt
    17341 tttgctagca aaactgaagt tgggatatat tctgttgcgc ttgctttagg taattcttgg
    17401 gggtttgtta actcttcaat tatttcttct ttcttcacaa aaatatattc tttgaaaaac
    17461 gaagccgatt ctcttattat ctctgctaaa ttaaatttat taatttttgt tattggttta
    17521 attatcacta tagggacttt aatatttgct ccctattttt tactttggtt ttatggtcca
    17581 ttatattccg atgcttatat acctctggtc atactttgta tgtcaacaac tgttgctggt
    17641 ttaggtggag tagcgacaag atatattgtc agacattcgg ggtactcatt tttgtccaaa
    17701 aaaatgttct tcactttaat tactagcgta ttgctatcag taccattagt ttatttttat
    17761 gggatagtag gagctgcaat agccactttt ttaactgaat tcatatcttt gactttatac
    17821 aactatttct ttaaaaatag agttatattt gatttgcata aatcttcagt attattcttt
    17881 cttaaagtta gaacataaat tttagatagt ctgataatat attatcaata taaacttctt
    17941 caagaattaa aggtgatacc catggaaatc aaaactaaaa tagcattgac tgctgactgg
    18001 ttagtatctt atgctggtgc cgagcgcgtt ataaaagaat taatagatct gtatcctaat
    18061 ttggacttgt tttctgtagt tgacttttta tccgatgaat cgcgaacgca ctttcaaggc
    18121 aaaagagcaa ccactacgtt tatacagcgg ctcccaaaag ctgaaacttc ttaccaaaaa
    18181 tatttaccgc ttatgccagt agccattgaa caacttgatg tttcagcata tgatattgtt
    18241 ttatcaagta gtcatgctgt agcaaagggg gtattaacag gccctgatca gatgcatatt
    18301 agttatgtac actcccctat ccgatatgct tgggatcttc agcaccagta tttacgtgaa
    18361 gcaaagctcg ataaaggtct gaagggtata attgctaaat atttattaca taaaataagg
    18421 ctatgggatt atcgcactgc aaatggagta aatcatttta ttgcaaactc acattttatt
    18481 gccagacgaa taaaaaaagt atatggaaga aatgctgacg tcatttatcc tcctgttgat
    18541 gtgcgtcgtt tcatattaaa cgaaaataaa gaagactatt atgttactgc ttctcgtctt
    18601 gtgccataca aaagaattga tctcattgta gatgcgtttg ctgccatgcc taataaaaaa
    18661 ttgattgtta taggtgatgg ctcagaaatg tcgaaaatca agagcaaagc aactactaat
    18721 gttgagatct taggttttca gccgaatgaa attatgcggg attatatgaa aaacgccaaa
    18781 gctttcgtgt ttgctgctga ggaagatttt ggtataaccc cggttgaagc tcaagcttgt
    18841 ggaactcccg tcattgcttt cggaaaaggt ggtagtcttg aaacgattcg tccttatggt
    18901 gttaacaaac ctactggagt ttttttcgct gaacaaactg ttccctcttt aatagatgct
    18961 attaatttat tcgagaacat atttgataaa ataacccccg aaaattgtag agaaaacgca
    19021 ttgcgctttt ccgttgacat atttaaagat accttttcaa agtatattga cgagaaatgg
    19081 tcggagttta atgttgcaaa aaaaattcaa tactaaatat tcttgagtct aatttttaga
    19141 ttagaaatta aatgaagagt gaactagaat gacaatacat tatcagcgag caaacgcaaa
    19201 tgcttcgctt atatctatgg ttcaaagatt ttctgatata gttctaattt tcgccagttt
    19261 atatgcaata tgtttgttga ataatgtgga ttttgaaata agatatttat tattttcact
    19321 tatagttctg gtcattttcc aaatggtcgg cggtattaca gatttctatc gttcttggcg
    19381 tggtgttaaa atatcagcag agctaaagtt aattttgaag aactggttcc taagttatgt
    19441 attagctctt gggattattt cattgttcca tgattttgac ctgaatatta gagttgctgc
    19501 tatttggttt attgtagtta ctataggctt tgtattgtgc agatcattga ttcgtgttgg
    19561 tgctggtata ctgagacgtc taggatataa tacacgtcgc gtagcagttg taggttcttt
    19621 accggcaggt attaatctgc tgaaaagttt cgccgaagaa ccttggatgg gttttatcgt
    19681 tttaggttac tacaatagcg aaccgttgac gagcgttagt gatatcaact tttgtggtaa
    19741 cttcgacaaa ttaattattg atgctcgtga tggtaaaatt gatagaatat atatagccat
    19801 gaatatgcag gaagaggcta agattaagaa aatcgtacaa caattgacag atacaacatg
    19861 ttctgttctg ttaattcctg atatttttac ctttaatatt ttgcaagcta gaacggaaga
    19921 aattaatggc gtgcctgttg tgccactatt tgacacccct cttagtggta ttaatatgat
    19981 tttcaagaga cttgaggata taatagtttc tactgtaatt ttgttactta tttctcctgt
    20041 gttgttaata atttcagtag ctgttaagtt ttcctcacca ggaccagttc ttttcagaca
    20101 attacgatat ggaatggatg gtaagcctat ccgcgtttgg aagtttcgtt ccatgcgcgt
    20161 tatggaaaac gacgaaaatg tcgtccaagc tacaaaaaat gatattcgtg ttactaaggt
    20221 cggtaaattt ttacgcagca cttctctcga tgaattacct cagttcttta acgtttggtg
    20281 tgggcaaatg tcagttgttg ggccccgacc acatgctgtt gcccataatg aacaataccg
    20341 tgcattaatt caaggctata tgcttcgcca taaagtcaaa ccaggcatta ctgggttggc
    20401 gcaaattaat ggctggcgtg gtgaaactga tactttagaa aaaatggaaa aaagaatcga
    20461 atatgatttg ttatatatca gaggttggag catttggtta gatctaaaaa taatattcct
    20521 tactgtcttt aaaggattta ttaacaaatc tgcttattga ttagatgctg ctcaagataa
    20581 gcattgtgca tttatagtcc aaaatttata tcttgcacta gttaacaaat tttcactatg
    20641 agctcttagt actttgggct aacattatca tcacatttaa gctgcgaaca tgtcgcagtg
    20701 accacaccag acaggagtat gtaatgtcca agcaacagat cggggttgtc ggtatggcgg
    20761 tgatggggcg taaccttgcg ctgaacatcg aaagccgtgg ttataccgtc tccgttttca
    20821 accgctcccg tgaaaaaacc gaagaagtga ttgccgaaaa tccaggcaag aaactggtcc
    20881 cttactacac agtacaagag ttcgttgaat cccttgaaac accacgtcgc atcctgttga
    20941 tggtgaaggc cggggctggt acagatagcg ccatcgattc cctgaagcct taccttgata
    21001 aaggcgacat catcattgat ggcggcaaca ccttcttcca ggacactatc cgtcgtaacc
    21061 gtgaactctc tgccgaaggt tttaacttta tcggtaccgg tgtatccggt ggtgaagagg
    21121 gggctctgaa agggccttcc atcatgccag gtggccagaa agaagcctat gaactggttt
    21181 ctccaatttt gaaacagatc gcggcggttg cagaagatgg tgagccatgt gtgacctata
    21241 tcggtgctga tggtgctggc cattatgtga agatggttca taacggcatc gagtatggtg
    21301 acatgcagct gattgccgaa gcttatgcgc tgttgaaagg cggtctggca ctttccaacg
    21361 aagagctggc gaaaaccttt accgaatgga atgaaggtga gctaagcagc tacctgatcg
    21421 acattaccaa agatatcttc accaagaagg atgaagaagg taagtacctc gttgatgtca
    21481 ttcttgatga agctgcaaac aaaggtaccg gtaagtggac cagccagagc tcactggatc
    21541 tcggcgaacc tctgtctctg atcaccgagt ccgtgtttgc tcgctatatt tcttcgctta
    21601 aagaccagcg tgtagccgcg tcgaaagtgc tgagtggtcc gcaggcgcag ccggccggtg
    21661 ataaagctga atttatcgaa aaagttcgtc gcgcgttgta cctaggtaaa atagtttcct
    21721 atgctcaggg cttctcccag ctgcgtgctg cttctgatga atacaactgg gatctgaact
    21781 acggcgagat cgctaagatt ttccgcgctg gctgcatcat tcgtgcgcag ttcctgcaga
    21841 agatcactga tgcttatgcg caaaacgctg gcattgctaa cctcctgctg gcgccgtact
    21901 tcaaacagat cgctgatgac tatcagcaag cgctgcgtga tgtcgtggct tatgccgtgc
    21961 agaatggtat tccggtaccg acgttctctg ccgcaattgc ctactacgac agctaccgtt
    22021 ccgcagttct gcccgctaac ctgattcagg ctcagcgtga ttactttggt gcgcacacct
    22081 ataagcgcac tgataaagaa ggtgtattcc ataccgagtg gttggaataa tctttatata
    22141 ccacagtcag gccaattggc ctgactgtta gctattgtta gttattctac aataatctga
    22201 tcaaagttat cttatttgca cgtcttcgtc atttatccag ctctaataaa gcaaattcgt
    22261 atcttttaag aatttgccat atttatactt ttgtatacct ataataagct acttctggcc
    22321 tcagaatata tctgggtgtt aaataacagg gttttaatta aaggaaatta atatgttact
    22381 tcctgtgata atggctggcg gtaccggcag tcgtctctgg ccgatgtctc gcgagcttta
    22441 cccgaaacag ttcctccgcc tgttcgggca gaactccatg ctgcaggaaa ccatcacccg
    22501 actctcgggc cttgaaatcc atgaaccgat ggtcatctgt aacgaagagc accgcttcct
    22561 ggtggccgaa cagctgcgcc agctcaacaa gctatcgaac aacattattc ttgagccggt
    22621 cgggcgcaac accgccccgg ccatcgccct ggcggccctt caggccaccc gtcacggcga
    22681 cgacccgctg atgctggtcc tcgccgccga ccatatcatc aataaccagc cggtcttcca
    22741 cgacgccatc cgcgtcgccg agcagtatgc cgatgaaggc catctggtca ccttcggtat
    22801 cgtgccgaac gccccggaaa ccggctacgg ctacatccag cgcggcgtgg ccctcaccga
    22861 cagcgcccac accccgtacc aggtggcccg cttcgtggag aaaccggacc gcgagcgcgc
    22921 cgaggcctac ctcgcctccg gggagtacta ctggaacagc ggcatgttta tgttccgcgc
    22981 caaaaaatac ctttccgagc tggccaaatt ccgcccggat atcctcgaag cctgccaggc
    23041 cgcggtcaat gccgccgata acggcagcga cttcatcagc atcccgcatg acattttctg
    23101 cgagtgcccg gacgagtccg tggactacgc ggtgatggag aaaaccgccg acgcggtggt
    23161 ggtcggtctc gatgccgact ggagcgacgt cggctcctgg tccgccctgt gggaggtcag
    23221 cccgaaagac gggcagggta acgtcctcag cggcgacgcg tgggtgcaca acagcgaaaa
    23281 ctgctacatc aacagcgacg agaagctggt ggcggccatc ggcgtggaga acctggtgat
    23341 tgtcagcacc aaggacgccg tgctggtgat gaaccgcgag cgttcccagg acgtgaagaa
    23401 ggcggtcgag ttcctcaagc agaaccagcg cagcgagtac aagcgccacc gcgagattta
    23461 ccgtccctgg ggccgctgcg acgtggtggt ccagaccccg cgcttcaacg tcaaccgcat
    23521 caccgtgaaa ccgggcggcg ccttctcgat gcagatgcac caccaccgcg ccgagcactg
    23581 ggtcattctc gccggcaccg gccaggtgac cgtcaacggc aagcagttcc tgctgaccga
    23641 gaaccagtcc acctttattc cgattggcgc cgagcacagc ctggaaaacc cgggccgcat
    23701 tccgctggaa gtgctggaga tccagtcggg gtcgtacctc ggcgaggacg acattattcg
    23761 tattaaagac cagtatggtc gttgctaatt ttttcgggac aaaacgcaga atgacacagt
    23821 taacatgctt taaggcttat gacatccgtg gtgaactggg cgaggagctg aacgaggaca
    23881 tcgcctaccg tatcggccgc gcctacggcg aatttctgaa acccgggaag atagtggtgg
    23941 ggggcgatgt gcgcctcacc agcgagtcgc tgaagctggc gctggcccgc gggctgatgg
    24001 acgccggcac cgacgtgctg gatatcggcc tgagcggcac ggaagagatt tacttcgcca
    24061 ctttccacct cggggtggac ggcggtatcg aggtgacggc gagccacaac ccgatgaact
    24121 acaacggcat gaagctggtg cgcgagaacg cgaagcccat cagcggcgac accgggctgc
    24181 gggatatcca gcgcctggcg gaggagaacc agttcccgcc ggtggacccg gcgcgtcgcg
    24241 ggaccctgcg ccagatttcg gtgctgaagg agtacgtcga ccacctgatg ggctacgtgg
    24301 acctggcgaa cttcacccgt ccgctgaagc tggtggtgaa ctccggcaac ggggcggcgg
    24361 ggcacgtgat tgatgaagtg gagaaacgct tcgcggcggc cggggcgccg gtgaccttta
    24421 tcaaggtgca tcaccagccg gacggccatt tcccgaacgg tatcccgaac ccgctgctgc
    24481 cggagtgccg ccaggacacc gccgacgcgg tgcgtgcgca tcaggcggac atggggatcg
    24541 cctttgacgg cgacttcgac cgctgcttcc tgttcgatga cgaggcgtcg tttatcgagg
    24601 ggtactacat tgtcggcctg ctggcggagg cgttcctgca gaagcagccg ggggcgaaaa
    24661 tcattcacga cccgcgtctg acgtggaaca cggtggacat cgtgacccgc agcggcggcc
    24721 agccggtgat gtcgaagacg gggcatgcgt tcatcaagga gcggatgcgc caggaagacg
    24781 ccatctacgg cggggagatg agcgcacacc attacttccg cgacttcgcc tactgcgaca
    24841 gcgggatgat cccgtggctg ctggtggcgg agctgctgtg cctgaagaac agttcgctga
    24901 aatcactggt ggcggaccgc caggcggcgt tcccggcgtc gggggagatc aaccgcaagc
    24961 tgggaaatgc ggcggaggcg atagcgcgca tccgggcgca gtatgagccg gcggccgcac
    25021 acatcgacac aacggacggt atcagtattg aataccctga gtggcgcttt aacctgcgca
    25081 cgtccaacac ggagccggtg gtgcgtctga acgttgagtc cagagcggat actgcgttaa
    25141 tgaatgcaaa aaccgaagag attttagccc tcctcaagta attcatgagc cataacggaa
    25201 gccatagggt cagatttgaa tcgtattttt gaccttatgg cttattcttg acatctcaca
    25261 ggtcaaagcg taaaaccgcc cacagcatta ttaaaattcg tggctatctg ccattaccca
    25321 gttaactgat taaagtgtaa tcgaatgaaa attactattt ccggtacagg ttatgttggt
    25381 ttatcgaacg gtatcctgat tgcgcaaaac cacgaagtgg tggccctgga tatcgtacag
    25441 gccaaagtgg atatgcttaa ccagaagatc tctccgattg tcgataaaga gattcaggaa
    25501 tatctggcag aaaaaccgtt aaatttccgt gccaccacgg acaagcacga cgcctatcgt
    25561 aatgccgact acgtgatcat tgcgacgccg accgattatg atcccaaaac taactact
//
