LOCUS       AB924572               22282 bp    DNA     linear   BCT 28-OCT-2015
DEFINITION  Klebsiella sp. 7522 DNA, capsular polysaccharide synthesis gene
            cluster, serotype: K34.
ACCESSION   AB924572
VERSION     AB924572.1
KEYWORDS    .
SOURCE      Klebsiella sp. 7522
  ORGANISM  Klebsiella sp. 7522
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella.
REFERENCE   1
  AUTHORS   Pan,Y.J., Lin,T.L., Chen,C.T., Chen,Y.Y., Hsieh,P.F., Hsu,C.R.,
            Wu,M.C. and Wang,J.T.
  TITLE     Genetic analysis of capsular polysaccharide synthesis gene clusters
            in 79 capsular types of Klebsiella spp
  JOURNAL   Sci Rep 5, 15573 (2015)
   PUBMED   26493302
  REMARK    DOI:10.1038/srep15573
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22282)
  AUTHORS   Pan,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2014) Contact:Yi-Jiun Pan National Taiwan
            University College of Medicine, Department of Microbiology; 1, Sec
            1, Jen-Ai Rd., Taipei 100, Taiwan
FEATURES             Location/Qualifiers
     source          1..22282
                     /organism="Klebsiella sp. 7522"
                     /mol_type="genomic DNA"
                     /strain="7522"
                     /serotype="K34"
                     /db_xref="taxon:1497811"
     gene            1682..2584
                     /gene="galF"
     CDS             1682..2584
                     /gene="galF"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose pyrophosphorylase"
                     /protein_id="BAT23627.1"
                     /translation="MKMNMANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVT
                     IMNVRQAQPLGLGHSILCARPVVGDNPFVVVLPDIILDGGTADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGR
                     YVLSADIWAELERTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQA
                     FVTYGMRNLKEGAKFRESIKKLLA"
     gene            2977..3606
                     /gene="cpsACP"
     CDS             2977..3606
                     /gene="cpsACP"
                     /note="orf2"
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase homologue"
                     /protein_id="BAT23628.1"
                     /translation="MNWQLISFFGDSTVLLPSAAALFIVLMLRKTSRLLAWQWSLLFG
                     ITGAIVCASKLAFMGWGLGIRELDYTGFSGHSALSAAFWPIFLWLLSARFSVGLRKAA
                     VITGYVLAAVVGYSRLVIHAHSVSEVIAGLLLGAAGSALFLVLQKRTPDPESVNISWG
                     GVACLVMVPLILLHSGSKAPTQSLLGQIATAVGPLDKPFTRTDLHKQAW"
     gene            4485..5999
                     /gene="wzi"
     CDS             4485..5999
                     /gene="wzi"
                     /codon_start=1
                     /transl_table=11
                     /product="surface assembly of capsule"
                     /protein_id="BAT23629.1"
                     /translation="MPRALSILVFPSFSLRYDSGAENGSCTMIKIARIAVTLGLLSSL
                     GVQAYAAGLVVNDNDLRNDLAWLSDRGVIHLSLSTWPLSQEEISRALKKAKPSYSSEQ
                     VVLARINQRLSALKADFRVTGYTSTDQPGTPQGFGQTQPADNSLGLAFNNSGEWWDIH
                     LQGNVEGGERISNGSRFNANGAYGAVKFWNQWLSFGQVPQWWGPGYEGSLIRGDAMRP
                     MTGFLMQRAEQAAPETWWLRWVGPWQYQISASQMNQYTAVPHTKIIGGRFTFTPFQSL
                     ELGASRIMQWGGEGRPESFSSFWDGFTGHDNTGTDNEPGNQLAGFDFKFKLEPTLGLP
                     ISFYAQMIGEDEAGFLPSANMYLGGIEGHHGWGKNAVNWYLETHDTRTNMSRTNYSYN
                     HHIYRDGYYQQGYPLGDAMGGDGQLIAGKVELITEDNQRWSTRLVYAKVNPENQSINK
                     AFPHADTLKGVQLGWSGNVYQSVRLNTSLWYTNADNSDSDDVGASAGIEIPFSL"
     gene            6144..7280
                     /gene="wza"
     CDS             6144..7280
                     /gene="wza"
                     /codon_start=1
                     /transl_table=11
                     /product="putative capsule polysaccharide export protein"
                     /protein_id="BAT23630.1"
                     /translation="MKKKIVKFSALALAIGFLSGCTIIPGQGLNSLRKNVVELPDSDY
                     DLDKLVNVYPMTPSLIDQLRPETVLARPNPQLDSLLRSYEYRIGVGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNSDGTIFYPYIGKVQVAGKTLSQVRQDIASRLTTYIESPQ
                     VDVSVAAFRSQKAYVTGEVAKSGQQAITNIPLTVMDAINAAGGLAEDADWRNVVLTHN
                     GKDKKISLYALMQKGDLTQNELLYPGDILFVPRNDDLKVFVMGEVGKQSTMKMDRSGM
                     TLAEALGNAEGMSQAFSDATGVFVIRQLKGDSKGKIANIYQLNAQDASAMVLGTEFQL
                     QPYDIVYVTTAPLVRWNRVISQLVPTITGVHDMTETAKYIRTWD"
     gene            7283..7717
                     /gene="wzb"
     CDS             7283..7717
                     /gene="wzb"
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="BAT23631.1"
                     /translation="MFDSILVICTGNICRSPIGERYLQQLLPEKRISSAGTGALIDHE
                     ADISALKIANANGLCLDGHRSRQFTGALGREYDLILAMDKSHIEYIGRIAPELRGKTM
                     LFGYWLSNKEIPDPYRKSEEAFASVYKLIVQAGQHWAEKLGA"
     gene            7733..9889
                     /gene="wzc"
     CDS             7733..9889
                     /gene="wzc"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="BAT23632.1"
                     /translation="MPSVTNKSQVKESDDFDLGRLIGELIDHRKLIISITAFFTVIAL
                     IYALFATPIYQADALIQVEQKQANAILGNLSQMLPDSQPQSAPEIALLQSRMILGKTV
                     DDLNLQAKVEQKYFPLFGKGLARLLGKKKNGIHISHLYVASDPEQDAEFSLTIKDNSH
                     YVITKGDYSTVGTVGSLLDTGKFSIKVDQIDSEPGTEFMVSYIPKLKAISDIQDVLNI
                     TDQGKDTGILTLSLTGEDTNLIKNILDSISSNYLAQNISRQAAQDEKSLEFLNLQLPK
                     VRSELDASEDRLNDYRRQSDSVDLSLEAKAVLDQIVNVDNQLNELTFRESEISQLYTK
                     EHPTYKALLEKKKTLQDEKSKLNKRVSAMPETQQEILRLSRDVESGRAVYMQLLNRQQ
                     ELNIAKSSAIGNVRIIDNAVTKTKAVKPKKALIVLMGFILGLVVSIGLVLLQIFLRRG
                     IESPEQLEELGINVYASVPVSETFVNQKNPKSKNQKEQEYSSFLAVDNPADLAVEAIR
                     GLRTSLHFAMMEARNNVLMISGASPNAGKTFISTNLAAVTAQTGKKVLFIDADMRKGY
                     THKLFNTDNDNGLSDILAGKSDINTALKRISTIGFDFISRGMVPPNPAELLMHRRFGE
                     VLKWAGENYDLVIIDTPPILAVTDAAIIGNYVGTTLLVSRFELNTAKEIEVSIKRFEQ
                     SGVTVKGCILNGVVKKASSYYSYGYNHYGYSYSEKK"
     gene            9923..10843
                     /gene="wcaA"
     CDS             9923..10843
                     /gene="wcaA"
                     /note="HG17; orf7"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23633.1"
                     /translation="MAEIMRAYIAIPTYNGGEVWEKCAKSIKKYSPHDTFVQIIDSGS
                     KDNTVEVAKKYGFHVKNISPQEFNHGGTRNYLVNIHKDEFDVVVFLTQDAIPEPDFYK
                     NIVSVFADKTVSCAYGRQLPHDDANPISSHARKFNYRAESYIANIDSVGSMGLKAAFI
                     SNSFSAYRLNIFIELGGFPKNTILSEDMYFAAKSLLAGYKVVYSAEAKVRHSHNYSAI
                     DEFKRYFDIGVFHADESWIRQKFGGAGGEGKKFIFSELKFLLKKAPFTIPRSAMHNFL
                     KILGYKLGQNYKVLPPRVVKKLSMHKNFWS"
     gene            10920..12317
                     /gene="wcaJ"
     CDS             10920..12317
                     /gene="wcaJ"
                     /note="HG10; orf8"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23634.1"
                     /translation="MTKSYHRVRSKPNASLISIVQRFADILIIFVGLYAVCWLNERPF
                     EYYQTLICLIVLAAFQMIGGISDFYRSWRGVKLSIELKLVLKNWTLSLICVMGIISYS
                     EVLALPFKILIEWYFFVCVGITICRSLIRTGARIIRYLGYNTRRIAIAGSMPAGINLA
                     KSFIEEPWLGFSVVGVYDNEKFESESNIQYRGDLEQLIKDAKNGELDRIYLAMSMSDE
                     SKMKQLIKALTDTTCSVILIPDIFTFNILQSRTEEVNGVPVVPLFDTPINGINMVLKR
                     LEDIIFSFIIILLISPLLVFIALAVKISSPGPVIFKQIRYGMDGKPIKVWKFRSMTVM
                     ENDTSIKQATKNDVRVTKVGKILRQTSLDELPQFFNVLTGGMSIVGPRPHAVAHNEQY
                     RNLIEGYMLRHKVKPGITGWAQINGWRGETDTVDKMQKRVEYDLEYIREWSIWLDLKI
                     IFLTIFKGFINKSAY"
     gene            12368..13432
                     /gene="rmlB"
     CDS             12368..13432
                     /gene="rmlB"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose-4,6-dehydratase"
                     /protein_id="BAT23635.1"
                     /translation="MKIIVTGGAGFIGSAVVRHIINETKDEVLVIDSLTYAGNLESLA
                     SVSKNPRFSFEQINICDKNGLDCIIKNFKPDSIMHLAAESHVDRSIDGPAAFIETNIV
                     GTYTLLESVRQYWNQLTNEAKSSFRFHHISTDEVYGDLHGTDDLFTESTPYAPSSPYS
                     ASKASSDHLVRAWHRTYGLPTIVTNCSNNYGPYHFPEKLIPLIILNALEGKSLPVYGN
                     GGQIRDWLYVEDHARALYKVVTEGLVGETYNIGGHNEQKNIDVVNKICELLEELVPQK
                     PEGVSNYSDLITYVTDRPGHDMRYAIDAKKIFDELGWKPEETFDTGLRKTVLWYLNNE
                     NWWRRVKDGSYAGERLGLAN"
     gene            13452..14321
                     /gene="rmlA"
     CDS             13452..14321
                     /gene="rmlA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyl-transferase"
                     /protein_id="BAT23636.1"
                     /translation="MKGIVLAGGSGTRLYPITKGTSKQLLPIYDKPMVYYPISVLMLA
                     GIRDILIITTPEDMPGFKRLLGDGSQFGVRFSYKVQPSPDGLAQAFLIGEEFIDGDRC
                     ALVLGDNIYFGESFGKKLESVVQRTTGATVFGYQVMDPERFGVVEFDETNKAISLEEK
                     PTIPKSNWAVTGLYFYDNQVVEMAKKVKPSHRGELEITTLNEMYLESGNLHVEKLGRG
                     FAWLDTGTHESLLEASQFIHTIEQRQGFKVACLEEIAYRKGWLNTEEVLAQAKLLAKT
                     QYGKYLLNLVEEK"
     gene            14324..14860
                     /gene="rmlC"
     CDS             14324..14860
                     /gene="rmlC"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-D-glucose-3,5-epimerase"
                     /protein_id="BAT23637.1"
                     /translation="MQIISTQIKDVKIILPKVFGDERGFFLETFEKKRYQDMLEIDYD
                     FVQDNHSRSTKGVLRGLHYQTVHPQGKLVRVVRGEVFDVAVDIRPNSPTYGKWEGVIL
                     SEENKKQFWIPPGLAHGFIVLSDIADFEYKCTDYYNPTGEGCLLWNDPQVGIQWPLSN
                     PMLSEKDKAGKLLKELKV"
     gene            14857..15714
                     /gene="rmlD"
     CDS             14857..15714
                     /gene="rmlD"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-L-mannose dehydrogenase/
                     dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAT23638.1"
                     /translation="MKILLTGSNGQLGSCFQDRVPSHWDILPTDSDTLDITNKDAVIS
                     IVDKFKPDVIVNAAAYTAVDKAEQDYELARLVNEVGPQNLAYAARLNGIRLVHVSTDY
                     VFDGTSNEPYVESDPTNPLGVYGTTKLAGEKCVLETLEDSIILRTAWVFSEYGNNFVK
                     TMLRIAKDNSTIKVVNDQIGCPTYAGDIALAIIELINFNSVGGIYHYCGGKNISWCGF
                     ASKIFEYAQKSGVLINVPIVIGISTSEYPTPVKRPSYSVLNTSKIEKIGVLPSDWESA
                     LETIMVKLK"
     gene            15735..16409
                     /gene="wzy"
     CDS             15735..16409
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAT23639.1"
                     /translation="MWKIYSQPMLLGCEMFEINIKEDGFTMPKREMTSKEMLVKYAIF
                     MLLVPLLTYLVGDKNIYQWNDYYTYPNYYNFSSETPLSGVFKQGMDPLFIVLMKPFTF
                     LDDGFSTFTIVCAYFTLLMKLSALRNSTENFFVLLVLYSSYILCLHDYVQIRISLALA
                     LIAFGIYTVNSRNIRYCLFLFAIFIHLTSVFVVLTYFVYKILGVRKFIFSHCFPSCSL
                     VCYQWV"
     CDS             16400..16789
                     /note="HG327; orf14"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein"
                     /protein_id="BAT23640.1"
                     /translation="MGIISNARLTTYIELASNKEKYYQINIFSSQPIIQIIGVLTIYF
                     DKKLRPYSRSYEYCMSVLGIFLFNSFSAVPVLSFRLFELTLFFYTILLSRCFNKSLIM
                     ILLSILYILVGLKNMFYGEMSLLHYWG"
     gene            16755..17582
                     /gene="wclL"
     CDS             16755..17582
                     /gene="wclL"
                     /note="HG106; orf15"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23641.1"
                     /translation="MVKCHYCIIGDDAYQQYMRRKLESKNEVVVYTALFGSYDKLLEP
                     TIKSSKCKFICFTDDKNLKSDFWEIRLVDGIVDPIAANRKMKFLPHQFLSDFKYSLYI
                     DSNIKIIHDPYDLIINYVQSFKINIPRHFERQCIYDELNECYNLNKINETELNNINQL
                     FLSEGYPPNNGLGENNIIIREHNDPFVINLMQEWWRFFSNGPKRDQLSLMFLAWKLDI
                     PINLMRESSRNRNKYFRYHLHLNEEKLPFIKRKYLYVRANRDRHFIYQMLYKLRNFF"
     CDS             17602..18453
                     /note="orf16"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23642.1"
                     /translation="MRFGVVVVLFDPNEENINNLAQFTTLGVKVCAVDNSAYGNVIPE
                     NYHYIHNNNQGGIAGAFNKGITYLLQNGCDFIFTFDQDSVLPHNFFDSMRDFISKNNA
                     KMVVPDFIDTNSRTHASFINLDKWSYKVTRTDKNTAFAISSGMGFDTSVWALIGPFTE
                     DYIIDHVDTEICLKALRNNISIFVNYDICLEHQIGNRSVHKFLGVTFKPNHHNYKRKY
                     YIVRNGTHLSLKYLIDYPSYFFMNFLRIVHELLCVVLYEKDKLRKLRYMLKGLFHAIC
                     GKLGAVS"
     CDS             complement(18542..18880)
                     /note="orf17"
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="BAT23643.1"
                     /translation="MTKDYISAININDNYPSFKNSNIYITEQKSNNPQLLMATPKQET
                     AIKINNAQKSNIYFTVSQYTKNINFTNSSNCTLKINNNKSDMNMKVHVSNNYNVRVLH
                     NDDSTPINNK"
     CDS             complement(19259..19900)
                     /note="orf18"
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="BAT23644.1"
                     /translation="MFIALKNDAIFHNDKACVADISSKLSWVRLESLNGIKKPEWYGC
                     VDDGITDDSDAFNSMLDSLHEGDTIVLGESRHYHNKLPKRDSRWIIKKSNVTIIGNDS
                     ILSRRATSQETMNIDGANLATLQISNVTNFEIRGKLLITSFENKSPLADKNGKIISTQ
                     TYPRAYVSSHGLFLEKVNKAILPTTLTCSNAVFPCYITESSNINISGTYINSG"
     gene            20287..21744
                     /gene="gnd"
     CDS             20287..21744
                     /gene="gnd"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate-6-phosphate dehydrogenase"
                     /protein_id="BAT23645.1"
                     /translation="MYNSNSYCNDSSRQEFIMTKQQIGVVGMAVMGRNLALNIESRGY
                     TVSVFNRSREKTEEVIAENPGKKLVPYYTVQEFIESLETPRRILLMVKAGAGTDSAID
                     SLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPG
                     GQKEAYELVAPILKQIAAVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAY
                     ALLKGGLALSNEELAQTFTEWNEGELSSYLIDITKDIFTKKDEEGKYLVDVILDEAAN
                     KGTGKWTSQSSLDLGEPLSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEF
                     IEKVRRALYLGKIVSYAQGFSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKIT
                     DAYAQNAGIANLLLAPYFKQIADDYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRS
                     AVLPANLIQAQRDYFGAHTYKRTDKEGVFHTEWMV"
BASE COUNT     6560 a   4139 c   4938 g   6645 t
ORIGIN
        1 acgtcataat actgctgacg ctgcgctgat taaggttcag cacccgctca atcatcagtc
       61 gttcctgcgg attaaacaga ggatgttgat cctgatcggc gaccagcgac gccgtgtcag
      121 catccagttc agctttttct ttctgaccgc tcagcagatt catcaccgct tcggtagtgc
      181 gctgacgcag cgtcatattg gcggagagga agcgacggcg gttaaactgc gccagctggt
      241 taagggcttc aatcatgacc gagaagccaa tggccgcata tagatagcct ttcggaataa
      301 taaagctgaa gccttcagca atcagactga agccgatcat cagcaggaag ctcagacaga
      361 ggatcacgat ggtcgggtgg ctgttaacga agcgcgtcag cgccttgctg gccatcagca
      421 tcaggctgat ggcgataacc acggcggcca tcatcaccgc caggtgatca accatgccga
      481 cggcggtgat caccgagtcg agtgagaaga tggcgtcgag caccacgatc tgcgccacga
      541 cggcccagaa tttcgcccct ttgcgctggg tggggttatc gctgtctttc ccctccagcc
      601 gctcattaag ctcgacggtc gctttaaaca gcagaaacag gccgccaaac agcataatta
      661 aatcgcgggc gctaaagctg aagtcgtgaa aaacaatcag cggtttggtc agggtgacca
      721 gccaggagat agaggccagc agcagaagac gcatgaccat cgccagcatc aggccagtga
      781 tccgcgcgcg atcgcgctgg gcgggaggga gcttctcggc gaggatagcg ataaagacca
      841 ggttatcgat acctaacacc agttcgataa ccaccagcgt gacgagacct gcccagattg
      901 acggatcggc aatccattcc atatgtatta aaacctgtac gactgcggta tgtgttacca
      961 cgatcatgga taagatgagt ctaaaatgca ataacgacgc ggatatcgcc ctgccgtgga
     1021 tggatatatt tccagtggat taagcgaacc gataagaatt atgttccgga aaagaacagt
     1081 gaaaaaataa caccatggcg gccaccatgg aataagcttg ccgatatcag aactttttcc
     1141 gctgcgtttc agcgagggcg gcaaaagggc ttcctcccgc ggttcgtcac ggtgagtgcg
     1201 gatgcgcaga gcagaagcga agcgcgaagc ccgctcacaa aaccggcaga attcatatta
     1261 tgaagtgagt gcagaatagg gcggatcgca gttcaccgcc gcggattcag gctaatatgt
     1321 cgtcatatcc ggctgtttat gctgaaatat attgcctggc gaaatttatt atctatatct
     1381 attctttcca ggcatacgcg cggcgcggcg gggccggcgg ccaacagacc ccgatagacg
     1441 ggcctctcag ccacatccac atcgcgcggc gcaaaggaac gagccgctga ataacctgaa
     1501 cgaaaataag attattctca cttctgactg ttggtaaaag ggagttgtgt gtattctttt
     1561 acgtgacagt gaatttaaga atttggcggg cagatgcccg ggcagtatcc gtgtattatc
     1621 agttccaatg gatttgtgac atgtacaatt ttgcaaaacc gcgtgttttg caaccaaaca
     1681 ggtgaagatg aatatggcga atttgaaagc ggttattccg gtcgcaggac taggcatgca
     1741 tatgctgccg gccacaaagg caattccaaa ggagatgctg ccgatcgttg ataagccaat
     1801 gattcagtac atcgttgacg aaatcgtcgc cgccgggatc aaagagattg ttctggtgac
     1861 gcactcatcg aagaacgcgg tggaaaacca cttcgacacc tcctacgagc tggaagccct
     1921 gctggaacag cgcgtgaagc gccagctgct ggcggaagtg caggccattt gcccgccggg
     1981 cgtgaccatc atgaacgtgc gtcaggcgca gccgctgggc ctgggccact ccatcctctg
     2041 cgcccggccg gtagtcggcg acaacccgtt tgtggtggtc ctgccggata tcatccttga
     2101 cggcggcacc gctgacccgc tgcgctataa cctcgccgct atgatcgccc gctttaacga
     2161 gaccggccgc agccaggtgc tggcgaaacg catgccgggc gatctctccg aatactccgt
     2221 catccagacc aaagagccga tggtggctga aggccaggtg gcgcgtatcg tcgagtttat
     2281 tgaaaaaccg gacgagccgc agactctgga ctccgatctg atggcggtgg ggcgctacgt
     2341 tctgtcggcg gatatctggg ccgaactgga acgtaccgag ccgggcgcat ggggccgtat
     2401 ccagctgacc gacgccattg ccgaactggc gaagaagcag tccgtcgacg cgatgctgat
     2461 gaccggcgaa agctacgact gcgggaagaa aatgggctac atgcaggcct tcgtcaccta
     2521 cgggatgcgt aacctgaaag aaggcgccaa attccgcgaa agtattaaaa aactgctggc
     2581 ctgagcgcca gcctgaaacc gagcggcaag gctgaagcat tcgtcctgcc gctcataacg
     2641 ttatgcagaa attattcata acgcgaatgt tataacgatt gtaaagaaac gtatggcttc
     2701 ggagacttct ggtagtttgt ctctggcctc tgtggtgcaa tggtcggagt agcggcaata
     2761 atgctttatg aatagtcact tagtgcgaca attcctaaag cgcagggaaa gcggtcaacg
     2821 acagccaaaa ataaaacttg actgcgatca tgtttccgct ttaaacatct cacttgcatg
     2881 cataaaaatg tgaaatgaat tggcatgcga gctggtacag acattacgga taatccctga
     2941 gcacggcagt ggacatcatc gaaggatcac aggtatatga actggcaact catctcattt
     3001 tttggcgata gcaccgtctt gctgcccagc gcagcggcgc tgtttattgt cctgatgctg
     3061 cgtaaaacgt cgcggttgct ggcgtggcag tggagtttgc tgttcggcat caccggcgct
     3121 atcgtctgcg cctctaaact ggcctttatg ggctggggtc tgggcattcg cgagctggat
     3181 tataccggct tcagcggcca ctccgcgctc tccgcggcct tctggcctat cttcctgtgg
     3241 ctgctcagcg cccgtttctc cgtcggtctg cgtaaagcgg ccgttattac cggctatgtt
     3301 ctggccgccg tagtgggcta ttcgcggctg gtcatccatg cgcattccgt ctcggaagtg
     3361 attgccggcc tgctgctggg cgctgctggc agcgctttgt tcctggtgtt gcaaaaacgt
     3421 acccctgatc cggaaagcgt gaatatctca tggggcggtg ttgcatgcct ggtgatggtt
     3481 ccgcttatcc tgttacatag cggcagcaaa gcgccgactc agtccctgct gggacaaatc
     3541 gccaccgctg tggggccgct ggataaaccc tttacacgta ccgatctgca caagcaggcc
     3601 tggtaatcgc catttgtttt acaggggaaa ttaagttttc gccggttaat tagacaaata
     3661 agaaaataat ctactatata cccggtaatt gataattcat atttatgaaa taatgaagtg
     3721 ctactacatt gttattgcat atttgccagg atatagcctt gatcagacgt ttcttaaatg
     3781 cactgagacg ttacctgatg cacattcaat gaatatccag acacaggaaa ctattagaaa
     3841 ttgtagttga ctaaaacgcc atcatctgat ttttgcatga tgatgagcta tgtaaaaaga
     3901 tgttttttta cagtcagtta gctgcatgtg tgatgatgta gcagtaccgg gaagatctct
     3961 aaccctggaa atcagtgaat aatcttaatt ggtgacccgc ttattttttg tcagtagaac
     4021 gacaggcggc attaattggc agatattcgg taacaacact cccaattgtg accgaaatcc
     4081 cgtaaactta acgccgccaa aaataatggc ctgaccaatt attcatccac aggtcgataa
     4141 aaaattaagt cgttcaggta gtcagtgcgc tggtagctgt taagccaggg gcggtagcgt
     4201 cgctgaagcc gcttgctgct gcacagaggt tctcttcaac ggctgtaaaa tcgttccggt
     4261 caggatgatc accctcaata gatatctatc aattttctac ggatatcctc agaagttggc
     4321 caggagcggc tgctgatatc gcctggagat taactttcct gtctcatcga tagcctgtag
     4381 ggtaaaattc gcctacattg tgagctgagt ggatgttata aggctaacaa gcagcttagg
     4441 gtaaatgtac ttgcctcgcc ggtgttgcac agcgaagtca gctgatgccg cgagcgcttt
     4501 ctatcttggt attcccctca ttctcattga gatacgacag cggggctgaa aatggatctt
     4561 gtacaatgat aaaaattgcg cgcattgccg tgacgttggg tttgctttcc tcactgggag
     4621 tccaggctta cgcggccggg ttagtggtaa atgacaacga cttgcgtaac gacctggcct
     4681 ggctttccga tcgcggggtc atccatctga gcctgtcgac ctggccgctg agccaggaag
     4741 aaatctcccg ggcgctaaaa aaggccaaac cgtcctattc ttctgagcaa gtggtgctgg
     4801 ctcgtattaa ccagcgactg tctgccttaa aagcggattt ccgggttacc ggctacactt
     4861 caaccgatca gccgggcact ccgcaggggt ttggtcagac acagccggca gataactcgt
     4921 taggcctggc gttcaacaac agcggcgagt ggtgggatat ccacctccag ggcaacgtcg
     4981 aaggagggga gcggatcagc aacggatcgc gcttcaacgc caacggcgcc tacggcgcgg
     5041 tgaagttctg gaaccagtgg ctctcttttg gccaggtacc acagtggtgg ggacctggct
     5101 atgaaggtag cctgatccgc ggggatgcca tgcggccgat gaccggtttc ctgatgcagc
     5161 gcgcagagca ggcggcgcca gagacatggt ggttacgctg ggtggggcca tggcagtatc
     5221 aaatctccgc aagccagatg aatcaatata ccgctgtgcc acatactaaa attatcggtg
     5281 gccgtttcac ctttacgccg ttccagtcat tagaattagg cgcatcacgc attatgcagt
     5341 ggggcgggga agggcgtcct gagtcattta gcagcttctg ggatggcttc actggccatg
     5401 ataataccgg gacggataac gaaccgggta accagctggc cggatttgac ttcaagttca
     5461 aactagaacc aactttgggc ttgccaataa gcttttacgc acagatgatc ggcgaagatg
     5521 aagctggctt ccttccatcg gctaatatgt atcttggcgg gatagaaggc catcacggct
     5581 ggggtaagaa tgcggtgaac tggtatctgg aaacgcatga tacccgtact aacatgagcc
     5641 ggacgaacta cagctataac catcatattt atagagatgg ttattaccag cagggatatc
     5701 cacttggcga tgcgatgggt ggggatggtc aactcattgc cgggaaggtt gagctgatta
     5761 ctgaggataa ccagcgctgg agcacgcgcc tggtgtacgc caaagtgaac ccagaaaatc
     5821 aatcgattaa taaagcattc cctcatgccg ataccctgaa aggtgttcag ctgggatgga
     5881 gtgggaatgt ttatcagtcg gttcgtctga atacttcttt gtggtatacc aacgctgaca
     5941 acagcgacag cgatgatgtt ggggccagtg cagggataga gataccgttt agtttataag
     6001 gctgaatgct gaaaacaggg gagagagggt ggtagcgctg caggatgcag tcagctcttt
     6061 tctctctaaa gccggcaggg aagcaatggc tatgacagct gctcaggaat tggcaaattt
     6121 tgatttactg atgatgtgac attatgaaga aaaaaattgt taaattttcg gcattagcgt
     6181 tggcaattgg gtttttatcg ggttgtacga ttatccctgg ccagggattg aatagtttac
     6241 gaaagaacgt ggttgagctt ccagacagtg actacgatct ggataagttg gttaatgttt
     6301 atccgatgac accaagcctg atcgaccagc tccgtccaga gactgtactt gctcgtccaa
     6361 acccgcagct ggatagttta ttgcgcagtt atgaataccg cattggggtt ggcgacgtat
     6421 taatggtaac cgtttgggat cacccggaac tgacaacacc agcaggtcag taccgtagcg
     6481 ccagcgacac tggtaactgg gttaactctg acggtaccat tttctatcca tatattggta
     6541 aggtgcaggt ggcgggcaaa acgcttagcc aggtacgcca agatatagct agtcgtttaa
     6601 ccacctatat tgaaagtccc caagtagatg ttagcgttgc tgcatttcgt tcgcaaaaag
     6661 catatgtaac gggtgaggtt gcaaaatcgg gacaacaggc aataactaac attccactca
     6721 ctgtcatgga tgcgataaat gcagcaggag ggctggcaga ggatgctgac tggcgtaatg
     6781 tagtcttgac gcataatggt aaagacaaaa aaatatcttt atatgccctt atgcaaaaag
     6841 gtgacttgac gcagaatgag ttgctctatc caggtgatat tttatttgtg ccacgtaatg
     6901 atgaccttaa agtatttgtc atgggtgagg tcggcaagca aagcactatg aagatggatc
     6961 gaagtggaat gacacttgca gaagcccttg gaaatgctga agggatgtca caagcattta
     7021 gcgatgcgac aggggttttc gtaattcgac agttaaaagg tgacagcaag ggaaagattg
     7081 ctaatatata tcagcttaat gcacaggatg cgtcagcgat ggtgttaggt acagaattcc
     7141 aattacagcc ttatgatatt gtttatgtta ctacggcgcc attggtacgt tggaaccgtg
     7201 tgatatcgca acttgtacca acaatcaccg gggtgcatga tatgactgag acagctaagt
     7261 atattcggac ttgggattga ttatgtttga ttctattctg gttatttgta cgggtaatat
     7321 ctgccgttca ccaattggag aacgctatct tcaacaatta ttacctgaga aaaggataag
     7381 ctctgctgga acaggtgctt taattgacca tgaagcagat atttctgctt tgaaaattgc
     7441 gaatgcaaat ggtctttgtc ttgatgggca tagaagtaga cagtttactg gcgctttagg
     7501 tagagaatat gacctcatac tagcaatgga taaatcacat atagagtata taggtagaat
     7561 tgcaccggag cttcgcggca aaacgatgtt gttcgggtat tggctttcaa acaaggaaat
     7621 accagatcca tacagaaaaa gtgaagaggc attcgcttct gtatacaaac taatcgttca
     7681 ggctggccag cattgggccg aaaaattagg cgcataaact aggaattaat gcatgccctc
     7741 agtaactaat aagtctcaag taaaagaatc agatgatttt gatctaggtc gtttgattgg
     7801 tgagttgatt gatcatagaa agctgattat ttcaattaca gcttttttta ctgttattgc
     7861 tttaatttat gcattatttg caacacctat atatcaagct gatgcattga ttcaggttga
     7921 acaaaagcaa gcgaatgcaa tcttaggtaa tttaagtcaa atgttaccgg atagccagcc
     7981 acagtccgca ccagagatag ctttgttaca atcgagaatg atattaggaa aaactgtaga
     8041 tgatctaaat ttacaagcta aagtcgagca aaaatatttt cctttattcg gtaaggggtt
     8101 agcacggcta ttgggtaaga agaagaatgg aatacatata tcacacttgt atgttgcaag
     8161 tgatcccgag caagatgctg aattttcatt aacaatcaag gataattctc actacgtaat
     8221 taccaagggg gattattcga cagttgggac tgtaggttct ctacttgata ctgggaaatt
     8281 ttcaattaaa gttgatcaga ttgattcgga gccagggacc gaatttatgg tctcatatat
     8341 tccaaaactg aaagcaatta gtgatattca agatgttttg aatatcactg atcagggtaa
     8401 agatacagga atattaacat tatctttaac tggagaagac acaaatttaa ttaagaacat
     8461 attagacagc attagtagca attatcttgc gcaaaatatt tcaaggcagg cagctcagga
     8521 cgagaaaagt ttagaatttc ttaatcttca gttgcccaaa gtgagaagtg aacttgatgc
     8581 gtctgaagat agattaaatg attatcgtcg gcaaagtgat tctgttgacc tttcgttaga
     8641 agcaaaagct gttcttgacc aaattgtaaa tgtagataat cagttaaatg aattaacttt
     8701 cagggaatca gaaatatcgc aactttatac aaaagagcat ccaacctata aggcactgct
     8761 agagaaaaaa aagacacttc aagatgaaaa atcaaaactg aataagcgtg tttctgctat
     8821 gcctgaaact caacaggaga tattaaggct tagtcgagat gtggaatcag gacgagcagt
     8881 atacatgcaa ttgcttaata ggcagcaaga gctaaatatt gcaaagtcaa gtgcaattgg
     8941 taacgttaga attatcgata atgcagttac aaagactaag gcagtcaaac ctaagaaagc
     9001 cttgattgta ttaatgggtt ttattttagg cttagtagtt tcaattggtc ttgttctgtt
     9061 gcaaatattc ctgcgtcgag gtatagagtc accagaacaa ctagaagaat tagggattaa
     9121 tgtttatgca agtgttcctg tctcagaaac atttgtaaat caaaaaaatc ctaaatctaa
     9181 aaatcagaaa gaacaagagt atagtagttt cttggcagtt gataatcctg cagatctagc
     9241 tgtcgaagct attagaggtt taagaacaag tctccatttt gcaatgatgg aagcaagaaa
     9301 taatgtttta atgatctctg gagcaagtcc taatgctggt aagacattta taagtacaaa
     9361 tttagcagca gtaactgctc aaacaggtaa aaaagtatta tttatagatg ctgatatgcg
     9421 gaaaggctat acccataagc tcttcaatac agataatgat aatggattat ctgatatatt
     9481 ggcagggaag tcggacatta atactgcatt gaaaagaata agcacaattg gttttgattt
     9541 tatctccaga ggaatggtgc caccaaatcc tgcggaatta ttaatgcatc gtcgctttgg
     9601 cgaagtttta aaatgggctg gtgaaaatta tgaccttgtt ataattgata caccgccaat
     9661 acttgctgtt acagatgcgg ctataattgg taattacgtt ggtacaacct tattagtatc
     9721 gcgctttgaa ttaaacactg ctaaagaaat agaagttagt attaaacgtt tcgagcaaag
     9781 tggcgttaca gtgaaaggtt gcattctaaa tggcgtcgtt aaaaaagcaa gtagctatta
     9841 tagctatggt tataaccact atggatattc ttatagtgaa aaaaaataaa cagatgccgg
     9901 tattccggca tctcaatcaa aaatggcaga aataatgaga gcatatattg caataccaac
     9961 atataatggc ggggaagtat gggagaaatg tgctaaaagt atcaaaaaat attcgccaca
    10021 tgatactttt gtacaaataa ttgattcggg cagcaaagat aatactgttg aagttgcaaa
    10081 aaaatatggg tttcacgtta aaaacattag cccacaagaa tttaatcatg gtggtactag
    10141 gaattacctc gtgaatattc ataaagatga atttgatgtg gtagtattcc taacacagga
    10201 tgcaatacct gaacccgact tttataagaa tatagtatct gtttttgctg ataagacagt
    10261 ttcatgtgcg tacggtagac agcttcctca tgatgatgct aatcccatct cttctcacgc
    10321 tcgaaaattc aactatcgag ctgaaagcta tatagcaaat atagatagcg taggaagtat
    10381 ggggttgaag gcagctttta tttcaaattc attttcagca tataggctca atatcttcat
    10441 tgaattgggc ggttttccaa aaaacacaat tcttagtgaa gatatgtatt ttgccgctaa
    10501 aagtctattg gcaggatata aggtcgtata tagtgctgaa gctaaagtac gccattcgca
    10561 taactatagt gcgattgatg agtttaagag atactttgat ataggagtgt ttcacgctga
    10621 cgaatcatgg atacgacaaa agtttggagg ggcaggaggt gaaggtaaaa aatttatttt
    10681 ttcagagcta aagtttttgt taaaaaaagc tccttttact attcctcgct ctgcaatgca
    10741 taatttttta aaaatattgg gatataagct tgggcaaaat tataaagttt tgccaccaag
    10801 agttgtaaaa aaattaagta tgcataaaaa tttttggtca taagtaatta aaaaatagat
    10861 aattttatta attgcattac ttaactgtat attattctaa taaagagcga ataatagcta
    10921 tgactaaatc gtatcatcgc gtgcgctcca aaccaaatgc atcattgata tcaattgttc
    10981 aacgattcgc tgatatcctg ataatttttg ttggattata cgcagtttgt tggttaaatg
    11041 agcgtccttt tgaatattat caaactctaa tatgtttaat cgtattggct gcatttcaaa
    11101 tgataggtgg aatttctgat ttctatcgtt cttggcgagg agtaaaacta tccatagagt
    11161 taaaattggt gctaaaaaat tggacattaa gcttgatttg tgtgatggga attatttcct
    11221 attcagaagt attagctctt ccatttaaga tactgataga gtggtatttt ttcgtttgcg
    11281 taggaataac gatttgtcgc tcactaataa gaacgggtgc aagaataatt agatacttag
    11341 ggtataatac ccgtagaata gcaattgccg ggtctatgcc tgctggtatt aatttagcaa
    11401 aaagtttcat agaagaaccg tggcttggtt tttcagtcgt tggagtatat gacaatgaaa
    11461 agtttgaaag tgaaagtaat atacaatata gaggtgattt agaacagttg attaaagacg
    11521 ctaaaaatgg ggagttagat cgtatatact tagctatgag tatgagtgat gaatcgaaaa
    11581 tgaaacagct tattaaggct ctcaccgaca caacttgctc cgtaattttg attcctgata
    11641 tatttacttt caatattctc caatctagga cagaagaagt aaatggagtt ccagttgttc
    11701 cattatttga taccccaata aatggtatca atatggtcct aaaaaggctt gaagatataa
    11761 tattttcttt cattattata ttgctgattt caccattgct agtcttcata gcattagctg
    11821 tcaaaatttc atcacctggt cccgtaatat tcaaacaaat ccgctatgga atggacggta
    11881 aaccgatcaa agtctggaag tttcgttcaa tgactgtcat ggaaaacgat acatcaatta
    11941 aacaagctac aaagaatgat gtaagagtga caaaagtagg gaaaatatta aggcaaactt
    12001 cacttgatga attacctcag ttttttaatg tcctcacagg tggaatgtcg attgttggtc
    12061 caaggccaca tgccgttgct cataacgagc agtatcgaaa cctaatagag gggtatatgt
    12121 tgagacataa agtgaaacca ggtattactg gctgggctca aataaacggc tggagaggag
    12181 agacggatac tgttgataaa atgcagaaaa gagtcgagta tgatcttgaa tatattaggg
    12241 aatggagcat atggttggat ttaaaaatca tctttctaac aatattcaaa ggttttataa
    12301 ataagtcggc ctattaattt tattatttaa ttaatgtttt ttgtactgaa aaattgagag
    12361 ataatatatg aaaattattg ttactggtgg tgcagggttt attggatctg cggttgtacg
    12421 tcatataatc aatgaaacta aagatgaggt tttagtaatt gattcattaa cttacgcagg
    12481 taatttggaa tcactggcgt ctgtttctaa aaaccctcgt ttttcatttg aacaaattaa
    12541 tatatgtgat aaaaatggac ttgattgcat tattaaaaat ttcaaaccag attcaataat
    12601 gcatttagct gcagaaagcc atgttgatcg ctctattgat ggccctgctg catttattga
    12661 aacaaatatt gttggcacat atacattatt agagtcagtt cgacaatatt ggaatcagtt
    12721 aactaatgag gcgaaatctt cattccgctt tcatcatata tcaactgacg aggtttatgg
    12781 tgacttacat ggcacagatg atttatttac tgaatccaca ccatatgccc caagtagtcc
    12841 atattcggca tcaaaggcat ctagtgacca tcttgttcgt gcatggcatc gcacatacgg
    12901 tttacccact atagtaacaa attgttcgaa taactatgga ccatatcatt tccctgaaaa
    12961 attaatacca cttatcattt taaatgcact agaaggaaaa tcgcttccag tttatgggaa
    13021 cggcggacaa attagagatt ggttatatgt tgaagaccat gctcgcgctc tatataaagt
    13081 tgttacggaa ggtttggttg gagaaacata caatattggt ggtcataacg aacaaaaaaa
    13141 tatcgatgtc gttaataaaa tttgtgagtt attagaagaa ttagtacctc aaaaacctga
    13201 aggtgtatcg aattattctg acctaattac ctatgttaca gatcgacctg gtcatgatat
    13261 gcgatatgca attgatgcga agaagatttt tgatgaatta ggatggaagc cagaagaaac
    13321 attcgataca ggtcttcgta agactgtatt gtggtatctc aataatgaaa attggtggcg
    13381 cagagtaaaa gatggttcat atgctggtga acgtttaggt ttggcaaatt aatcataaag
    13441 gataacatat aatgaaaggt atcgttttag ctggtggttc aggcacacgt ttatatccta
    13501 ttacaaaagg aacatctaaa caactgctac ccatttatga taaaccaatg gtatattatc
    13561 ctatctcagt tcttatgctc gctggcatac gtgatatttt aattattact actcctgaag
    13621 atatgcctgg ctttaagcgc cttctcggag acggttctca atttggtgtt cgatttagtt
    13681 ataaagttca gccaagccct gatgggctag cacaagcctt tcttattggt gaggaattta
    13741 tcgacggaga taggtgtgca ttagttttgg gggataatat ttattttggc gaaagttttg
    13801 gtaaaaaact tgaatctgtt gtacagagaa caactggggc tacagtcttt ggataccaag
    13861 taatggatcc agaaagattc ggtgttgttg aatttgacga aaccaataaa gctatctctc
    13921 tagaagaaaa acctacaatt ccaaaaagta actgggccgt tacgggattg tatttctatg
    13981 ataatcaggt cgttgaaatg gccaaaaaag ttaaaccttc acaccggggt gagttggaaa
    14041 ttaccacatt aaatgaaatg tatttagaga gtggcaattt gcacgtggag aaattaggtc
    14101 gtggttttgc atggcttgat actggaactc atgaaagttt gcttgaagct tctcaattta
    14161 tacatacgat agagcaaagg caaggcttta aggttgcatg cttagaagag atagcttatc
    14221 gcaagggatg gcttaataca gaagaggtac ttgcacaggc taagctacta gctaaaactc
    14281 aatatggtaa atatttacta aatttagttg aggagaaata agtatgcaaa ttatcagtac
    14341 gcagatcaaa gatgttaaaa tcatattacc taaagtattt ggagatgaac ggggcttttt
    14401 tctagagaca tttgaaaaaa aacgttatca ggatatgtta gaaatagatt atgattttgt
    14461 tcaggataat cattctcgat ctacaaaagg tgttttgaga ggtttgcatt atcaaactgt
    14521 tcatcctcaa ggaaaattag ttagggttgt tcgtggtgag gtttttgatg tagctgtaga
    14581 tattcgacct aattcaccaa cgtatggaaa atgggaaggt gtgatcctat cagaggaaaa
    14641 taaaaaacaa ttttggattc ctcccggact tgctcatggc ttcattgtgc tttctgatat
    14701 agcagatttc gaatataaat gtacggatta ttataatcct accggtgaag gttgtcttct
    14761 ttggaatgat cctcaagtgg gtatacagtg gccattgtcg aacccgatgc tttcagaaaa
    14821 agataaagca ggtaagcttt tgaaggagct caaagtatga aaattctgtt aactggatct
    14881 aatggccagt tgggaagctg ttttcaagat cgggtgccct cacattggga tattttaccc
    14941 acagattcag atactcttga tataacaaat aaagacgcag taatttccat tgttgataaa
    15001 tttaaaccag atgttatagt gaatgctgct gcatatactg ctgttgataa agcagaacaa
    15061 gattatgagt tggcaagatt agttaatgaa gttggtccgc aaaacttggc ttatgcggct
    15121 agacttaatg gtatccgatt agtccatgta tctactgatt atgtttttga tggtacatct
    15181 aatgagccat atgtcgaatc tgatcctaca aacccgttgg gtgtgtatgg aacaactaag
    15241 ttagctggtg aaaaatgtgt tcttgagact cttgaggatt caatcatttt acgcactgct
    15301 tgggtcttca gtgaatatgg gaataacttt gtaaaaacaa tgttgcggat tgccaaggat
    15361 aattcaacga ttaaagttgt caatgaccaa ataggctgtc caacatatgc aggagatatc
    15421 gctcttgcga taattgaact aattaatttc aattctgttg gtggtatata ccactattgt
    15481 ggcggaaaaa atatttcatg gtgtgggttc gcatcaaaaa tattcgaata tgcccaaaag
    15541 tctggcgtac ttataaatgt accaattgtt ataggtataa gtactagcga atatccaaca
    15601 ccggttaaac gcccttcgta ttcagtattg aatacatcta agattgaaaa aatcggtgtg
    15661 ctaccttctg attgggaatc cgctttagaa acgattatgg taaaattaaa ataatttaat
    15721 cgttaatatt attaatgtgg aaaatatact cacaacctat gcttttaggt tgtgagatgt
    15781 ttgagattaa tataaaagaa gatggcttta caatgcccaa gagggaaatg acctctaaag
    15841 aaatgttagt aaaatatgca atatttatgc tgcttgtgcc cttattgaca tatttggttg
    15901 gggataagaa tatatatcaa tggaatgatt attatactta tcccaattat tataacttct
    15961 catctgaaac acctctttct ggtgttttca agcagggaat ggatccttta tttatagtct
    16021 taatgaagcc gtttacattt ttggatgatg ggttttctac ttttactatt gtttgcgctt
    16081 actttacact gcttatgaag ctttctgcgc tacgaaatag tactgaaaat ttttttgtat
    16141 tacttgtatt atattcatcg tacatacttt gcttacatga ctatgttcag atacgaatct
    16201 ctttggcact ggcgctaatc gcatttggaa tatacactgt taactcaaga aatattcggt
    16261 attgtttatt tctatttgcg attttcatac atttgacatc tgtatttgta gtattaactt
    16321 attttgttta taagatttta ggtgttagga aattcatttt ttctcactgt tttccatcct
    16381 gttccctagt ttgttatcag tgggtataat ttctaacgca agacttacta cttatataga
    16441 gttagcttcg aataaagaaa aatattatca aataaatatt ttttcttccc agcctattat
    16501 tcaaattatt ggtgttctaa ctatttattt tgataaaaag ttgagaccat attcaagatc
    16561 ctatgaatat tgcatgtcag ttctaggaat attcctattc aactctttta gtgcggtgcc
    16621 agtattatca tttcggttgt ttgagctaac cttatttttt tatacaatac ttttatcaag
    16681 atgttttaat aagtcattaa ttatgattct gttaagtata ctttatattt tggttggact
    16741 taaaaatatg ttctatggtg aaatgtcatt attgcattat tggggatgat gcatatcaac
    16801 aatatatgag gcgtaaattg gaaagtaaga atgaagttgt tgtttatacg gcgctatttg
    16861 gctcttatga caagttacta gaacctacta ttaaatcatc aaaatgtaaa tttatatgtt
    16921 tcaccgatga taaaaattta aagtctgact tttgggagat caggttggtc gatgggattg
    16981 ttgaccccat agcggcaaac aggaagatga aattccttcc tcaccaattt ttatctgact
    17041 tcaagtatag tctttatatt gattctaata ttaagataat acatgatcca tatgatctga
    17101 ttattaatta tgtacagtct tttaaaataa atatccctcg ccattttgaa cgccaatgta
    17161 tttatgatga gttaaatgaa tgctataatt tgaataaaat taatgaaact gaacttaata
    17221 atataaatca actattttta tcggaaggct accctccaaa taatggatta ggtgaaaata
    17281 atattattat tcgtgagcat aacgatcctt ttgttataaa tctcatgcaa gaatggtggc
    17341 gttttttctc taatggacca aaaagagatc aactcagttt aatgttttta gcatggaaat
    17401 tggatattcc aataaattta atgagagaat cttctaggaa taggaataaa tatttccgtt
    17461 accatctaca tttgaatgaa gaaaaattac cattcataaa aaggaaatat ctatatgtta
    17521 gggcaaatag agatagacat tttatttatc aaatgctcta taaattgcga aatttctttt
    17581 gatttttaag gagtaataat catgcgtttc ggagttgtcg ttgtactatt tgatccgaat
    17641 gaagaaaata taaataatct tgctcaattc actacgcttg gtgttaaagt ttgtgctgtt
    17701 gataacagcg catatggtaa tgtaatacct gaaaattatc attatattca taataataat
    17761 caaggcggga tagccggtgc ctttaataaa ggtataacct accttttgca aaacggttgt
    17821 gattttattt ttactttcga tcaagattct gttttaccac ataacttttt tgattcgatg
    17881 cgggatttca tatcgaagaa taacgctaaa atggtcgtgc ctgattttat tgatacaaat
    17941 tctagaactc atgcttcttt tataaatcta gataaatggt catacaaagt tacaagaact
    18001 gataagaata ccgcctttgc tatttcttct gggatggggt tcgatacttc tgtctgggcg
    18061 ttaatcggcc catttaccga agattacata attgatcatg ttgatacgga aatttgttta
    18121 aaagccctgc gtaataatat aagtatattc gttaattatg atatatgctt ggaacatcag
    18181 attggcaatc gaagtgtgca taaatttttg ggcgtgactt ttaaacctaa ccatcacaat
    18241 tataaaagaa aatattatat agttcgtaac ggaacacatt taagtcttaa atatttaatt
    18301 gattatccct catacttctt tatgaatttt ttgcgtatag ttcacgagtt gctatgtgtg
    18361 gtcttgtacg aaaaagataa attaagaaaa ttgagatata tgctcaaagg attgtttcat
    18421 gcaatatgtg gtaaattagg ggctgtttcg taatttttat atcaaatagg acaataatat
    18481 cagcatcaat ttcacatgat gctgtattat ttattattta ttatttatta tttattattt
    18541 attatttatt atttattgga gtcgagtcat cattgtgtaa gactcttacg ttataattat
    18601 ttgacacatg aactttcata ttcatgtcag acttattgtt atttatctta agtgtgcagt
    18661 tagaactatt tgtaaaattt atatttttag tatattgcga aactgtaaag taaatgtttg
    18721 atttttgggc gttgtttatt ttaattgctg tttcttgttt gggggttgcc attaaaagtt
    18781 gtgggttatt agatttctgt tcagttatat atatgttaga attcttgaag ctagggtagt
    18841 tgtcattgat gtttattgct gaaatataat ctttcgtcac atcaattaca gttagattca
    18901 ggtctagttc ttcacatata ttatcatgtt ctgaaacaat aattcaccca tagctggatt
    18961 gtatggtttt aattattgcc tttatcttat ttgagcctga gctaattctt aatcctgcac
    19021 cctgcgcgtt tttggataat atatttgctt taatattttc actattttga tggataatac
    19081 atccatgcat gaatgtgttt actgaattaa tgttaactgt accatttttg ctgtaaggct
    19141 caatttcgca tccgcaatat gcgcagtctt tacagagcac attaactgtg aacccatctg
    19201 attttgagat cttcagaccg gagccaattt gtaagtcatc ccctcttaca gggtatactt
    19261 atcctgagtt aatgtaagtc cctgaaatgt taatattgct tgattctgtt atatagcatg
    19321 gaaagactgc attactacac gttagtgttg ttggaagaat tgctttattt accttttcaa
    19381 ggaatagacc atgtgaacta acataagccc gtggataagt ctgggtacta atgatttttc
    19441 catttttatc cgctagtggt gatttgtttt caaacgaagt gattagtagt tttcccctaa
    19501 tctcaaaatt agttacatta gatatctgta aggttgcaag atttgctccg tcgatattca
    19561 ttgtttcttg actggtggca cgccgtgata aaattgaatc attaccaatg atagtgacgt
    19621 tgctcttttt tattatccag cgtgaatctc ttttaggaag tttattatga taatgtctac
    19681 tttctcctaa aactatagta tcaccttcat gtaaggaatc taacatgctg ttgaaagcat
    19741 cggaatcatc agtaattcca tcgtcaacgc atccatacca ctctggcttt ttaatgccat
    19801 ttaaactttc taagcgaacc catgataact tggatgatat gtctgccacg catgctttgt
    19861 cattatgaaa gatagcatcg ttctttaagg caataaacat accacctcct ataccactgt
    19921 cctcatgata agaacttaac tctatcaatg agtttatttc tgttgcagga tatttcttta
    19981 attcattgaa ggattttact tttttaaaac aatagttttt tcgtttgcaa atattcttga
    20041 cttgcccaat cccaataatg gtaaagttag tgatattttt aataatgttc ttcgttttat
    20101 cattgtgtcc tccttattta tatctcatcg cagtataatc atattaaaac atattgtaaa
    20161 acatatcatt ctatgttagc aaggaaatga atttataatg agtggaatac ttgttgtttt
    20221 tttacgttga cgatcagttg tattatttat aatcacgaat tttaaagtgc ttactagcta
    20281 cgtaatgtgt ataattctaa cagttactgt aatgattcga gtagacagga gtttataatg
    20341 accaagcaac aaattggggt tgtcggtatg gctgtgatgg ggcgtaacct tgcgctgaac
    20401 atcgaaagcc gtggttatac cgtctccgtt ttcaaccgct cccgtgaaaa gacagaagaa
    20461 gtgattgccg aaaatccagg caagaagctg gttccttact acacagtaca agagtttatt
    20521 gaatccctcg aaacaccacg tcgtatcctg ttgatggtga aggccggggc tggcactgac
    20581 agcgccatcg attccctgaa gccttacctt gataaaggtg acatcatcat tgatggcggc
    20641 aacaccttct tccaggacac catccgccgt aaccgtgagc tgtctgccga aggttttaac
    20701 tttatcggta ccggtgtttc tggtggtgaa gagggggctc tgaaagggcc ttccatcatg
    20761 cctggtgggc agaaagaagc ctatgagtta gttgctccga ttctgaagca gattgctgcg
    20821 gttgctgaag acggtgagcc atgtgtaacc tatatcggtg ctgacggtgc tggccattat
    20881 gtgaagatgg ttcataacgg catcgagtat ggtgacatgc agctgattgc tgaagcttat
    20941 gcgcttttga aaggcggtct ggctctttca aacgaagagc tggcgcaaac cttcaccgaa
    21001 tggaacgaag gtgaactgag cagctacctg atcgacatta ccaaagatat cttcaccaag
    21061 aaggatgaag aaggtaagta cctcgttgat gttattcttg atgaagctgc aaacaaaggt
    21121 accggcaagt ggaccagcca gagctcactg gatctcggcg aacctctgtc tctgattacc
    21181 gagtccgtat ttgctcgtta tatctcttcg ctaaaagacc agcgtgtagc tgcttcgaaa
    21241 gtgctgagtg gtccgcaggc tcagccggcc ggcgataaag ctgaatttat cgaaaaagtg
    21301 cgtcgcgcgt tatacctcgg taaaatcgtt tcctatgctc agggcttctc ccagctgcgt
    21361 gctgcttccg atgaatacaa ctgggatctt aactacggcg agatcgctaa gattttccgc
    21421 gctggctgta tcattcgtgc gcagttcctg cagaagatca ccgatgctta tgcgcaaaac
    21481 gctggcattg ctaacctcct gctggcgccg tacttcaaac agatcgctga tgactatcag
    21541 caagcgctgc gtgatgtcgt ggcttatgcc gtgcagaatg gtattccggt accgacgttc
    21601 tcagccgcga ttgcttacta cgacagctac cgttccgcag ttctgccagc taacctgatt
    21661 caggctcagc gtgattactt tggtgcgcac acatataagc gtaccgataa agaaggtgtg
    21721 ttccatactg agtggatggt ttgatttata tttttaatta atgataaggc cctgcttcat
    21781 gctgggcctt atcattctaa ttttgagcac atgttcattt ttttaaatat taattcggtg
    21841 ttttttcttt tggctattta ttaactttat tatattttaa aggtagtact ttctacagac
    21901 ttcattccat gactattagt cgttatccaa ttaacagatt aaagtgtaat ctaaaatgaa
    21961 aattactatt tccggtacag gttatgttgg tttatcgaac ggtgtcctga ttgcgcaaaa
    22021 ccacgaagtg gttgccctgg atatcgtaca ggccaaagtg gatatgctta accagaagat
    22081 ctctccgatt gtcgataaag agattcagga atatctggca gaaaaaccgt taaatttccg
    22141 tgccaccacg gataagcacg acgcttaccg taatgccgac tacgtgatca ttgccacgcc
    22201 gaccgattac gatcctaaaa ccaactactt caacacctct acggtggaag cggttattcg
    22261 cgatgtcaca gagatcaacc cg
//
