LOCUS       AB924582               24325 bp    DNA     linear   BCT 28-OCT-2015
DEFINITION  Klebsiella sp. 8464 DNA, capsular polysaccharide synthesis gene
            cluster, serotype: K45.
ACCESSION   AB924582
VERSION     AB924582.1
KEYWORDS    .
SOURCE      Klebsiella sp. 8464
  ORGANISM  Klebsiella sp. 8464
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella.
REFERENCE   1
  AUTHORS   Pan,Y.J., Lin,T.L., Chen,C.T., Chen,Y.Y., Hsieh,P.F., Hsu,C.R.,
            Wu,M.C. and Wang,J.T.
  TITLE     Genetic analysis of capsular polysaccharide synthesis gene clusters
            in 79 capsular types of Klebsiella spp
  JOURNAL   Sci Rep 5, 15573 (2015)
   PUBMED   26493302
  REMARK    DOI:10.1038/srep15573
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24325)
  AUTHORS   Pan,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2014) Contact:Yi-Jiun Pan National Taiwan
            University College of Medicine, Department of Microbiology; 1, Sec
            1, Jen-Ai Rd., Taipei 100, Taiwan
FEATURES             Location/Qualifiers
     source          1..24325
                     /organism="Klebsiella sp. 8464"
                     /mol_type="genomic DNA"
                     /strain="8464"
                     /serotype="K45"
                     /db_xref="taxon:1339196"
     gene            169..1071
                     /gene="galF"
     CDS             169..1071
                     /gene="galF"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose pyrophosphorylase"
                     /protein_id="BAT23833.1"
                     /translation="MKMNMANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVT
                     IMNVRQAQPLGLGHSILCARPVVGDNPFVVVLPDIILDGGTADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGR
                     YVLSADIWAELERTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQA
                     FVTYGMRNLKEGAKFRESIKKLLA"
     gene            1464..2093
                     /gene="cpsACP"
     CDS             1464..2093
                     /gene="cpsACP"
                     /note="orf2"
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase homologue"
                     /protein_id="BAT23834.1"
                     /translation="MNWQLISFFGDSTVLLPSAAALFIVLMLRKTSRLLAWQWSLLFG
                     ITGAIVCASKLAFMGWGLGIRELDYTGFSGHSALSAAFWPIFLWLLSARFSVGLRKAA
                     VITGYVLAAVVGYSRLVIHAHSVSEVIAGLLLGAAGSALFLVLQKRTPDPESVNISWG
                     GVACLVMVPLILLHSGSKAPTQSLLGQIATAVGPLDKPFTRTDLHKQAW"
     gene            2971..4485
                     /gene="wzi"
     CDS             2971..4485
                     /gene="wzi"
                     /codon_start=1
                     /transl_table=11
                     /product="surface assembly of capsule"
                     /protein_id="BAT23835.1"
                     /translation="MPRALSILVFPSFSLRYDSGAENGSCTMIKIARIAVTLGLLSSL
                     GAQAYAAGLVVNDNDLRNDLAWLSNRGVIHLSLSTWPLSQEKISRALKKAKPSYSSEQ
                     VVLARINHRLSALKADFRVTGYTSTDQPGTPQGFGQTQPENNSLGLAFNNSGKWWDVH
                     LQGNVKGGERISNGSRFNANGAYGAVKFWNQWFSFGQVPQWWGPGYEGSLIRGDAMRP
                     MTGFLMHRAKQAAPETWWLRWVGPWQYQISASQMNHYTAVPHTKIIGGRFTFSPFQSL
                     ELGASRIMQWGGEGVLSHLAASGMASLAMIIPGRITNRVTSWPGFDFKFKLEPTLGWP
                     VSFYGQMVGEDESGYLPSANMFLGGVEGHHGWGKDAVNWYLEAHDTRTNMSRTNYSYI
                     HHIYKDGYYQQGYPLGDAMGGDGQLIAGKVELITEDNQRWSTRIVYAKVNPENQSINK
                     AFPHADTLKGVQLGWSGDVYQSVRLNTSLWYTNANNSDSDDVGASAGIEIPFSL"
     gene            4631..5767
                     /gene="wza"
     CDS             4631..5767
                     /gene="wza"
                     /codon_start=1
                     /transl_table=11
                     /product="putative capsule polysaccharide export protein"
                     /protein_id="BAT23836.1"
                     /translation="MKKKIVRFSALALAIGFLSGCTIIPGQGLNSLRKNVVELPDSDY
                     DLDKLVNVYPMTPGLIDQLRPETVLARPNPQLDNLLRSYEYRIGVGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNSDGTIFYPYIGKVQVAGKTLAQVRQDIASRLTTYIESPQ
                     VDVSVAAFRSQKAYVTGEVEKSGQQPITNIPLTVMDAINAAGGLSENADWRNVVLTHN
                     GKDTKISLYALMQKGDLTENRLLYPGDILFVPRNDDLKVFVMGEVGKQSTMKMDRSGM
                     TLAEALGNAEGMSQAFSDATGVFVIRQLKGDKQGKIANVYQLNAQDASAMVLGTEFQL
                     QPYDIVYVTTAPLVRWNRVISQLVPTISGVHDMTETVKFVKDMQ"
     gene            5767..6201
                     /gene="wzb"
     CDS             5767..6201
                     /gene="wzb"
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="BAT23837.1"
                     /translation="MFDSILVVCTGNICRSPIGERFLQKALPTKKIDSAGTNALIGHK
                     ADDSAIKIAEKHGISLAEHVGRQFTSVIGRQYDLILVMEKYHIEKIGQIAPELRGKTM
                     LFGQWLNQKEIPDPYRKSDEAFASVYQLIELAGLRWVEKLGA"
     gene            6221..8386
                     /gene="wzc"
     CDS             6221..8386
                     /gene="wzc"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="BAT23838.1"
                     /translation="MSSVKNRTVEKEADEIDLGRLVGELIDHRKLIISVTALFTLIAL
                     LYALFATPIYQADALLQVEQKQGNAILNSLSQMLPDSQPQSAPEIALLQSRMILGKTV
                     DDLNLQAKIEQSYFPLLGKGWARLVGEKKGILVVSRLYLSSDSDTEIPKLKLKVKDAN
                     NYIVTFNDHEFEGKVGVLLDSNGISLKVDSIEAKPGTEFVISYVSKLQAITDLQEIFS
                     VADQGKDTGILSLSLTGPDPLLLEKTLNSISNNYLAQNVARQAAQDAKSLEFLNQQLP
                     KVRNDLDIAEDKLNQYRRQKDSVDLSLEAKSVLEQIVNVDNQLNELTFRESEISQLYT
                     KEHPTYKALMEKRKTLQDEKAKLNERVSAMPKTQQDILQLSRDVDSGQAVYMQLLNRQ
                     QELNIAKSSAIGNVRIIDDAVSQPKPVKPKKIIIVLVGIVLGGMISIGIVLLRIFLRR
                     GIESPEQLEELGINVYANIPISETFANKALQNTKLRRKAGSEYQSFLAVDNPADLAIE
                     AIRGLRTSLHFAMMEARNNVLMISGASPNAGKTFVSSNLAAIIAQTGKKVLFIDTDMR
                     KGYTHKLFNLSNDNGLSDVLSGKIEVSKAIKKVSSAGFDYISRGMVPPNPAELLMHRR
                     LGELITLVSQSYDIVILDTPPILAVTDAAIIGNYVGTTLLIARFEQNTTKEIEVSVKR
                     FEQAGVSVKGCILNGVVKKASSYYGYGYSHYGYSYSDKK"
     gene            8434..9342
                     /gene="wcaA"
     CDS             8434..9342
                     /gene="wcaA"
                     /note="HG17; orf7"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23839.1"
                     /translation="MKAYIAIPTFNGSDVWKQAARNIKKYSPDGILVQIIDSGSKDET
                     VEVALSNGFKVYSINPADFNHGGTRNLAVELHKDEYDIVIFLTQDAIPEPDFYEKIVN
                     VFNNPLVSCAYGRQLPHYNANPISQHARYFNYPRSSYISSKADISRLGLKTVFTSNSF
                     AAYRISTFIELEGFPDSTILSEDMFFAAKSIMTGYSVAYVSDAIVRHSHNYSTLEEFK
                     RYFDIGVFQTDEPWIKQNFGGAGGEGKKFLVSEIRYLLKNNPIYIPVSAIHNFAKILG
                     YKLGQNYKKIPVSVIKNFSMHRRFWN"
     gene            9404..10804
                     /gene="wcaJ"
     CDS             9404..10804
                     /gene="wcaJ"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23840.1"
                     /translation="MAMKTFNHRGRSKPNASLISIVQRFTDISIIFVGLYASCLINNK
                     YFGYNQILVCLIVLSAFQMIGGISDFYRSWRGVKLSVELSLVLKNWTLSLLLSMGITT
                     YSEVLGLSFKIMLEWYFFVCLGVVICRMSIRAGARFIRTLGYNTRRIAIAGSMPVAIN
                     LAKSFIDEPWLGFVVVGIYDNKIVKNNEIEYKGDFNKLIVDAKAGELDRIYLAMSMSD
                     EIEMRELIRNLTNTTCSVILIPDIFTFNILQSRTEEVNGVPVVPLFDTPINGINMVFK
                     RLEDIFLSLLIIILISPILLVIAVAVKVSSPGPVIFKQKRYGMDGKAIKVWKFRSMTV
                     MENDTLVKQATKNDVRVTKVGSFLRKTSLDELPQFFNVLSGKMSIVGPRPHAVAHNEQ
                     YRNIIEGYMLRHKVKPGITGWAQINGWRGETDTIDKMEKRIEYDLEYIREWSIWLDLK
                     IILLTVFKGFINKSAY"
     gene            11498..12370
                     /gene="wcuP"
     CDS             11498..12370
                     /gene="wcuP"
                     /note="HG41; orf9"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23841.1"
                     /translation="MLVGGDMNISQPLVTIYISTYNRLEKLKRAINSVLQQDYTNWEL
                     IVCDDASCDGTSDYMNDICMKDSRIRYLRNDVNKGACETRNLGIFNAKGTFITGLDDD
                     DEFTNDRISFFIDNWSDEYSFLCCNFKNRYVDNNDLIHYKCNSKDFLLLSYKDLLFDN
                     TASNQIFTLTARLQEIGGFDKRVKRLQDWDTWLRLSFKFGEFIRFNKATYIMHHDHHI
                     SELRVSQNEIITKSLLDLALRNKEIYSDEDFLFMNFIIDQKNNNASLYDGIYWSYKKR
                     NPKHFLKYMVKIFR"
     gene            12426..13322
                     /gene="wclI"
     CDS             12426..13322
                     /gene="wclI"
                     /note="HG102; orf10"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23842.1"
                     /translation="MMSIGNIFAIIVTYNPQLDKVKKLALSLKQQNVNPLIIDNGTLG
                     ENDLESFRNIAHVILLGNNEGIAKAQNIGIRFAKENAADGVIFFDQDSEISDNFVESL
                     ISDYMSVSKYDNTIGMIGPTFIDSRYKFYYKQILLNRFGVRKKIDPAKLSTPFKVSII
                     ISSGSFVLMPILDSVGYMDERFFIDYVDTEWCFRMLSKGYSIYVSTSATMEHAIGDKM
                     INFWGLHIPVHSPVRRYYRIRNAIIFLNYKHIPLLLKLRDNAMNIIHQSLIIINEKDK
                     QENFKIAYKSIIDGLKGKTGKL"
     gene            13892..15067
                     /gene="wzy"
     CDS             13892..15067
                     /gene="wzy"
                     /note="orf11"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAT23843.1"
                     /translation="MKNLYLNPLYLFGYAFLAAMGMYALSLSGLYVNGDSTLTITLFI
                     LSILSLMLGFIFNSIFGTKMNSDLKGEYDKFLTPNYIFMLFGFLVDCLASGAVPLVNI
                     LRGELYEYKDFGLKTFHVFYMAYMSAFAIVSFERYFITKNKKFLLPVLTGLAITIFIV
                     SRGATMLLVMPMALLYLSQKKAGKKTGKIKKNFTIITVVLIFIIGFGYIGDKRMIASG
                     YKSDTAIMEIGQANDIFYSIPSGFFWVYLYASSPYANLASQERFANVDKGDLEDFFAS
                     SVLPDFISKYTAPYVFTKFQPKRITEELTVGTGFSFALVSFGIVGVILLYFWMVFLSF
                     FLAWANRNMYINSICAVLSSTAVLMIFDNMFIFASCVLQMLMLTIFTRVKIGKYYFM"
     gene            15148..16632
                     /gene="wcqB"
     CDS             15148..16632
                     /gene="wcqB"
                     /note="HG193; orf12"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23844.1"
                     /translation="MERRKFVVSALSAVAVTYAGHTKASEHRNTDLSLSKSVDNINIL
                     LKENKIKKSLNLEPEGEGIPLTDWILGNIRSLFLYLTKDKIDSINAAIPVDVTTELNS
                     AMQDNIPIFIPSGNYIITSSINVGIRSGLIGAGAKSVLIDNRSSDHAFIFPVGYDRGT
                     KDFLGFSIESSIGTAKDKYAFYLSSAADGRLNYSVGWRFVGIEINGQGMGGGWYLQDC
                     FRVTIRDCGASSLSNPFYLAGSVVQLTVDNFVNNGDNQPKTNIGSYGVYMTTKKYSDE
                     NGIKMPEGITFINCKFVKQEVGAHALGLYVQFVNTEFDYSSKFGGFYAGGDKVDFINC
                     YVGTTHVRNNDFVAFMVQAHASKVPEPVLISNCTINMQKNSSDGYKSYGVILSGEKDF
                     ISGAKVVDCFFRGDGYENCILVKRVDGVIIDHNTFKVRGENVKVESAKNITISNNFAL
                     GNYSLPNPEPDYCWIITGNTGDFSDVDLSEAKKSLIVNQGLMRN"
     gene            17372..18604
                     /gene="wzx"
     CDS             17372..18604
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAT23845.1"
                     /translation="MMSEKIITLFGLIFVTSFVAKYVGTEVFGQIAFATSLFQIAMII
                     AQLGSDVIIFKRVSKNNKSGARLISATLYLRSFIYFFAAVPIVFISYEKNDVGSIYFI
                     IACAISCFFSAMDVFSIYYDARLESRKNTVVNVVGLIVSLFFRWLIAFFHLDPIYLSF
                     PIILTGFIPFILRWAIFRKELVRNKLNARCKIKYMKYLIGAGITFVVSTISVAIYTRI
                     SMLSLGYFYDKSLVGIFSVSVSLATSWSFVCNSLITSSLPSIFSEKNDAQATLKASRL
                     NTIIIACSMPIILLTYLFGSFFIRVLYGGDYVSAFTPLVILSFSTMISSLGIISARFI
                     ARFSGYTFLSKKMLSVVIFSFIINIPLIYYYGMLGAAVATLLTELLSLTIFNYLFRRG
                     IVLKMHLMTFFPRLLKSP"
     gene            18750..20156
                     /gene="gnd"
     CDS             18750..20156
                     /gene="gnd"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate-6-phosphate dehydrogenase"
                     /protein_id="BAT23846.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA
                     ENPGKKLVPYYTVQEFVESLETPRRILLMVKAGAGTDSAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILEKIS
                     ARAEDGEPCVAYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLALSNEELAAT
                     FTEWNAGELSSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLTGPQAQLAGDKAEFVEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYEQNASIANLLLAPY
                     FKQIADEYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRTDKEGVFHTEWME"
     gene            20398..21462
                     /gene="rmlB"
     CDS             20398..21462
                     /gene="rmlB"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose-4,6-dehydratase"
                     /protein_id="BAT23847.1"
                     /translation="MKILVTGGAGFIGSAVVRHIIENTQDEVRVMDCLTYAGNLESLA
                     TVADSERYSFTQTDITDAKSVSEQFSDFRPDIVMHLAAESHVDRSIDGPAAFIQTNLI
                     GTFTLLEAARHYYSTLDAAQKQAFRFHHISTDEVYGDLHGTDDLFTEETPYAPSSPYS
                     ASKAGSDHLVRAWNRTYGLPVVVTNCSNNYGPYHFPEKLIPLTILNALAGKPLPVYGN
                     GEQIRDWLYVEDHARALYKVATEGESGETYNIGGHNERKNIDVVRTICAILDKVVEQK
                     PGNISQFADLITFVKDRPGHDLRYAIDAAKIQRDLGWVPQETFESGIEKTVHWYLNNQ
                     TWWQRVLDGSYAGERLGLNN"
     gene            21489..22358
                     /gene="rmlA"
     CDS             21489..22358
                     /gene="rmlA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyl-transferase"
                     /protein_id="BAT23848.1"
                     /translation="MKGIVLAGGSGTRLYPITQGVSKQLLPIYDKPMIFYPVSVLMLA
                     GIRDILIISTPDDMPSFQRLLGDGSQFGVNFSYAIQPSPDGLAQAFIIGEKFIGNDAC
                     ALVLGDNIYFGQSFGKKLEAAAAKTSGATVFGYQVLDPERFGVVEFDENFKALSIEEK
                     PLKPKSDWAVTGLYFYDNNVVEMAKDVKPSERGELEITTLNQMYLERGDLQVELLGRG
                     FAWLDTGTHDSLIEASQFIHTIEKRQGMKVACLEEIAYRNQWLSAEGVAAQAERLKKT
                     EYGAYLKRLLNER"
     gene            22390..23280
                     /gene="rmlD"
     CDS             22390..23280
                     /gene="rmlD"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-L-mannose dehydrogenase/
                     dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAT23849.1"
                     /translation="MKILLIGKNGQVGWELQRSLSTLGDVVAVDYFDKELCGDLTNLD
                     GIAQTVRIVRPDVVVNAAAHTAVDKAESERELSDLLNDKGVAVLAAESAKLGALMVHY
                     STDYVFDGAGSHYRREDEATGPLNVYGETKRAGELALEQGNPRHLIFRTSWVYATRGA
                     NFAKTMLRLAGEKETLSIIDDQHGAPTGAELLADCTATAIRETLRDPALAGTYHLVAS
                     GETSWCDYARYVFEVARAHGAELAVQEVKGIPTTAYPTPAKRPLNSRLSNEKFQQAFG
                     VTLPDWRQGVARVVTEVLGK"
     gene            23295..23849
                     /gene="rmlC"
     CDS             23295..23849
                     /gene="rmlC"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-D-glucose-3,5-epimerase"
                     /protein_id="BAT23850.1"
                     /translation="MNIIKTDIPEVLIFEPRVFGDARGFFFESFSSKVFNEAVGRQVE
                     FVQDNHSQSQKGVLRGLHYQLDPHAQGKLVRCVEGEVFDVAVDIRRSSPTFGKWVGAV
                     LSAENKRQLWIPEGFAHGFMALSDTVQFVYKATNYYAPQSERSIIWNDPEIGIDWPAL
                     GDCALSLSEKDLQAHTLATAEVYK"
BASE COUNT     6900 a   4615 c   5625 g   7185 t
ORIGIN
        1 attttctcct ttctactgtt ggtaaaggga gttgtgtgta ttcttttacg tgacagtgaa
       61 tttaagaatt tggcgggcag atgcccgggc agtatccgtg tattatcagt tccaatggat
      121 ttgtgacatg tacaattttg caaaaccgcg tgttttgcaa ccaaacaggt gaagatgaat
      181 atggcgaatt tgaaagcggt tattccggtc gcaggactag gcatgcatat gctgccggcc
      241 acaaaggcaa ttccaaagga gatgctgccg atcgttgata agccaatgat tcagtacatc
      301 gttgacgaaa tcgtcgccgc cgggatcaaa gagattgttc tggtgacgca ctcctcgaag
      361 aacgcggtgg aaaaccactt cgacacctcc tacgagctgg aagcccttct ggaacagcgc
      421 gtgaagcgcc agttgctggc ggaagtgcag gccatttgcc cgccgggcgt gaccatcatg
      481 aacgtgcgtc aggcgcagcc gctgggcctg ggccactcca tcctctgcgc ccgcccggta
      541 gtcggcgaca acccgtttgt ggtggtcctg ccggatatca tccttgacgg cggcaccgct
      601 gacccgctgc gctataacct cgccgctatg atcgcccgct ttaacgagac cggccgcagc
      661 caggtgctgg cgaaacgcat gccgggcgat ctctccgaat actccgtcat ccagaccaaa
      721 gagccgatgg tggctgaagg ccaggtggcg cgtatcgtcg agtttattga aaaaccggac
      781 gagccgcaga ctctggactc cgatctgatg gcggtggggc gctatgtgct gtcggcggat
      841 atctgggccg aactggaacg taccgagccg ggcgcatggg gccgtatcca gctgaccgac
      901 gccattgctg aactggcgaa gaagcagtcc gtcgacgcga tgctgatgac cggcgaaagc
      961 tacgactgcg ggaagaaaat gggctacatg caggccttcg tcacctacgg gatgcgtaac
     1021 ctgaaagaag gcgccaaatt ccgcgaaagc attaaaaaac tgctggcctg agcgccagcc
     1081 tgaaaccgag cggcaaggct gaagcattcg tcctgccgct cataacgtta tgcagaaatt
     1141 attcataacg cgaatgttat aacgattgta aagaaacgta tggcttcgga gacttctggt
     1201 agtttgtctc tggcctctgt ggtgcaatgg tcggagtagc ggcaataatg ctttatgaat
     1261 agtcacttag tgcgacaatt cctaaagcga agggaaagcg gtcaacgaca gccaaaaata
     1321 aaacttgact gcgatcatgt ttccgcttta aacatctcac ttgcatgcat aaaaatgtga
     1381 aatgaattgg catgcgagct ggtacagaca ttacggataa tccctgagca cggcagtgga
     1441 catcatcgaa ggatcacagg tatatgaact ggcaactcat ctcatttttt ggcgatagca
     1501 ccgtcttgct gcccagcgca gcggcgctgt ttattgtcct gatgctgcgt aaaacgtcgc
     1561 ggttgctggc gtggcagtgg agtttgctgt tcggcatcac cggcgctatc gtctgcgcct
     1621 ctaaactggc ctttatgggc tgggggctgg gcattcgcga gctggattat accggcttca
     1681 gcggtcactc cgcgctctcc gcggccttct ggcctatctt cctgtggctg ctcagcgccc
     1741 gtttctccgt cggtctgcgt aaagcggccg ttattaccgg ctatgttctg gccgccgtgg
     1801 tgggctattc gcggctggtc atccatgcgc attccgtctc ggaagtgatt gccggcctgc
     1861 tgctgggcgc tgctggcagc gctttgttcc tggtgttgca aaaacgtacc cctgatccgg
     1921 aaagcgtgaa tatctcatgg ggcggtgttg catgcctggt gatggttccg cttatccttt
     1981 tacatagcgg cagcaaagcg ccgactcagt ccctgctggg acaaatcgcc accgcggtgg
     2041 ggccgctgga taaacccttt acgcgtaccg atctccacaa gcaggcctgg taatcgccat
     2101 ttgttttaca ggggaaatta agttttcgcc ggttaattag acaaataaga aaataatcta
     2161 ctatataccc ggtaattgat aattcatatt tatgaaataa tgaagtgcta ctacattgtt
     2221 attgcatatt tgcctggata tagccttgat cagacgtttc ttaaatgcgc tgagacgtta
     2281 cctgatgcac attcaatgaa tatccagaca caggaaacta ttagaaattg tagttgacta
     2341 taacgccatc atctgatttt tgcatgatga tgagctatgg aaaaagacgt ttttttacag
     2401 tcagttagct gcatgtgtga tgttgtagca gtaccgggaa gatttctaac cctggaaatc
     2461 agtgaataat cttaattggt gacccgctta ttttttgtca gtagaacgac aggcggcatt
     2521 aattggcaga tattcggtaa caacactccc aattgtgacc gaaatcccgt aaacttaacg
     2581 ccgccaaaaa taatggcctg accaattatt catccacagg tcgataaaaa ttaagtcgtt
     2641 caggtagtca gtgcgctggt agctgttaag ccaggggcgg tagcgtcgct gaagccgctt
     2701 gctgctgcac agaggttctc ttcaacggct gtaagtatcg acccggtcag gatgatcatc
     2761 atcaatagat atctaccaat tttctacgga atcctcagaa gttggccagg agcggctgct
     2821 aatatcgcct ggatattaac tttcctgtct catccatagc ctgtagggta aaattcgcct
     2881 acattgtgag ctgagtggat gttataaggc taacaagcag cttagggtaa atgtacttgc
     2941 ctcgccggtg ttgcacagcg aagtcagctg gtgccgcgag cgctttctat cttggtattc
     3001 ccctcattct cattgagata cgacagcggg gctgaaaatg gatcttgtac aatgataaaa
     3061 attgcgcgca ttgccgtgac gttgggtttg ctttcctccc tgggagccca ggcttacgcg
     3121 gccgggttag tggtaaatga caacgacttg cgtaacgacc tggcctggct ttccaatcgc
     3181 ggggtcatcc atctgagcct gtcgacctgg ccgctgagcc aggaaaagat ctcccgggcg
     3241 ctaaaaaagg ccaaaccgtc ctattcttct gaacaggtgg tgctggcgcg tattaaccac
     3301 cgcctgtctg ccttaaaagc ggatttccgg gttaccggct acacttcaac cgatcagccg
     3361 ggcactccgc aggggtttgg tcaaacacag ccggaaaata actcgttagg cctggcgttc
     3421 aacaacagcg gcaagtggtg ggatgtccac ctccagggca acgtcaaagg aggggagcgg
     3481 atcagcaacg gctcgcgctt caacgccaac ggcgcatacg gcgcggtgaa gttctggaac
     3541 cagtggttct cttttggtca ggttccgcag tggtggggac ctggctatga aggtagcctg
     3601 atccgcgggg atgcgatgcg gccgatgacc ggtttcctga tgcaccgcgc aaagcaggcg
     3661 gcgccggaaa cctggtggtt acgctgggtg gggccatggc agtaccagat ctccgccagc
     3721 cagatgaatc attataccgc tgtgccacat acaaaaatta tcggcggtcg ttttactttc
     3781 tcacctttcc agtcactgga attaggtgct tcgcgcatta tgcaatgggg cggggaaggc
     3841 gtcctgagtc atttagcagc ttctgggatg gcttcactgg ccatgataat accgggacgg
     3901 ataacgaacc gggtaaccag ctggccggga tttgacttta aattcaaact cgagccgact
     3961 ctagggtggc cggtgagttt ctatgggcaa atggtcggcg aggatgagtc tggctacctg
     4021 ccttccgcga atatgttcct tggtggagtg gaagggcacc acggctgggg taaggatgca
     4081 gtgaactggt atctggaagc gcatgataca cgtaccaata tgagccggac gaattacagc
     4141 tatatccacc acatctataa agatggttat taccaacaag ggtatccact gggggatgcg
     4201 atgggtgggg atggtcaact cattgccggg aaggttgagc tgattactga agataaccag
     4261 cgctggagta cgcgcatcgt ttacgccaag gttaacccgg agaaccagtc gatcaacaaa
     4321 gcattcccac atgccgatac cttgaaaggt gtacagctag gctggagcgg ggatgtttat
     4381 cagtctgttc gtctgaatac ctctttgtgg tacacaaacg ctaacaacag cgacagcgat
     4441 gatgttgggg caagcgcagg gatagaaata ccgtttagtt tataaggctg aatgctgaaa
     4501 atgaggggag agcggtggta gcgctgcagg atgcagtcag cttttctctc tccgcaggct
     4561 ggtaaggaag caacggccat gacagctgct caggaattgg caaattttga tttactgatg
     4621 atgtgacatt atgaagaaaa aaattgttag attttcggca ttagcattgg cgattgggtt
     4681 tttatcgggt tgtacaatca tcccaggtca gggattaaac agtctacgca agaatgtggt
     4741 tgagcttccg gatagcgact acgatctgga taaactggtg aacgtgtatc caatgactcc
     4801 aggactgatc gatcaactcc gtccggagac tgtactcgct cgtccaaatc cgcagcttga
     4861 taatttacta cgcagttatg aatatcgcat cggtgtgggt gatgtactga tggtcaccgt
     4921 ttgggatcac ccggaactga ccacacctgc aggccaatat cgtagcgcca gcgacaccgg
     4981 taactgggtt aactctgatg gtaccatttt ctatccttat attggtaagg tgcaggtagc
     5041 gggaaaaact ctcgctcagg tacgacagga tatagcaagt cgtttgacca cttatattga
     5101 aagcccgcag gttgatgtaa gcgtagctgc gttccgttca caaaaggcct atgtgactgg
     5161 agaagttgaa aaatcaggcc agcagccaat cactaatatc cctttaacag ttatggatgc
     5221 gataaacgct gccgggggac tatccgaaaa cgctgactgg cgtaatgttg tgctgacaca
     5281 taatggtaaa gatactaaaa tctctctcta tgctctaatg caaaaagggg atttaaccga
     5341 gaaccggttg ctgtatccag gagatatttt atttgttcca cggaatgacg atttaaaagt
     5401 attcgttatg ggtgaggtgg gcaaacaaag cacaatgaag atggatcgta gtggcatgac
     5461 gcttgcagag gcactgggta atgctgaagg tatgtctcaa gccttcagcg atgctacagg
     5521 tgtttttgtt attcgccaat tgaaaggtga taagcaaggt aaaatagcaa atgtttatca
     5581 attgaatgct caggatgctt cggcaatggt gctcggcact gaatttcagc tacaacccta
     5641 tgacattgtg tatgtgacga ctgcgccact tgttcgctgg aacagggtca tttctcagtt
     5701 ggtaccaacg atcagtggcg tacatgacat gactgaaacc gttaagtttg tcaaggatat
     5761 gcaataatgt ttgattctat tcttgtcgtt tgtacgggaa atatatgtcg ttctccaatt
     5821 ggggaacgtt ttttacagaa agccttgcct acaaagaaaa ttgattctgc agggactaat
     5881 gcattgatag gccataaagc tgatgatagt gcaattaaga ttgcggaaaa acatggtatt
     5941 tcattagcgg aacatgtagg acgtcagttt acttctgtta ttggtcgaca atatgatctg
     6001 attttagtaa tggaaaaata tcatattgaa aaaattggac agattgcccc ggagttgaga
     6061 ggtaaaacaa tgctttttgg ccaatggctt aaccaaaaag aaattcctga tccatatcgc
     6121 aaaagtgatg aagcatttgc atctgtatat cagttaatcg agttagctgg cttacgttgg
     6181 gttgagaaat taggcgcata ataactatca ggaaaattgc atgtcatcag taaaaaatag
     6241 aactgttgag aaagaggcag atgagatcga tttaggccgt ttagttggag agcttatcga
     6301 tcatagaaaa ctcattattt cggttacggc gttatttact ttaatcgctc tgctttatgc
     6361 actttttgca acgcctatct atcaggctga tgcgttgtta caagtagagc aaaagcaagg
     6421 taatgctatt ctgaatagtc taagccaaat gttacctgac agtcagcctc aatctgcacc
     6481 agaaattgca ttgttgcaat ctcgtatgat tctgggaaaa actgtagatg atctaaattt
     6541 acaagctaag atcgaacaaa gttattttcc gttattaggt aaaggatggg ctcgtttggt
     6601 aggagaaaaa aaagggattt tagttgttag ccgactctat ttgtcatctg acagcgacac
     6661 agaaatacca aaattaaaac tgaaggtaaa ggacgcgaac aactatattg ttacttttaa
     6721 tgatcacgag ttcgaaggca aagtcggggt tttgctcgat tcaaatggca tttcgcttaa
     6781 agttgatagt attgaggcta aacctggaac tgagtttgtt atatcttatg ttagtaagct
     6841 gcaagctata actgacttac aagaaatttt ttcagtagca gatcaaggaa aagatactgg
     6901 aatattaagc ctatctttaa ctggcccaga tccacttttg ctagagaaaa cgctaaacag
     6961 catcagtaat aattatcttg cacaaaatgt agcgcgccaa gcagcacagg atgctaaaag
     7021 tctagagttt ttaaaccaac aactgcctaa agtacgcaat gatttagata ttgctgaaga
     7081 taagctaaat caatatcggc gccaaaaaga ttctgtagat ctttcgttag aagccaaatc
     7141 agtacttgaa caaatagtta atgtcgataa tcagcttaat gaattgacat tccgtgaatc
     7201 agaaatctcg cagctttata ctaaagaaca tccaacctat aaggcgctta tggaaaagcg
     7261 taaaactttg caggatgaga aagcaaagct taatgaacgt gtttcagcaa tgccgaaaac
     7321 acagcaagat atcttacagt taagcagaga tgtagattct gggcaagctg tttacatgca
     7381 gcttcttaat cgtcaacagg aactcaatat tgcaaaatct agcgctattg gcaatgttag
     7441 aattattgat gatgctgtgt cccaaccgaa accagtaaaa ccgaagaaaa taataattgt
     7501 acttgttggg attgttctgg gaggtatgat atctataggc atagtattgt taaggatctt
     7561 cttgcgtcga gggatcgaaa gtcccgagca acttgaagaa cttggaatta acgtatatgc
     7621 gaatatacct atttctgaga cttttgctaa taaggctctt caaaatacaa aattgagaag
     7681 aaaagcaggc agtgaatatc agagcttttt agcggttgat aaccctgcgg atttggcaat
     7741 agaagctatc cgcggtttgc gtacaagcct gcacttcgca atgatggaag cacgaaacaa
     7801 tgtcttgatg atttctggag ctagccctaa tgccgggaag acttttgtta gctctaatct
     7861 tgctgcaata attgctcaaa ctggaaaaaa agtacttttt atagacaccg atatgagaaa
     7921 gggttatacc cacaagttgt tcaatttgag taatgataat ggactttcgg atgtattgtc
     7981 gggaaaaatt gaagtaagta aagcaattaa aaaagtatct tctgcaggct ttgattatat
     8041 ttcacgaggt atggtcccac ctaatccagc agaattatta atgcatcgta gattaggtga
     8101 gctaataacg ttggttagtc aaagttatga catcgttata ttagatacgc caccaatact
     8161 agcggttact gatgctgcta ttattgggaa ttatgttgga acaacattat tgatagcccg
     8221 atttgaacaa aatacgacaa aagaaattga agtaagtgtt aaacgattcg aacaagccgg
     8281 tgtgtctgtg aagggctgta tattgaatgg tgttgttaaa aaagcaagta gctattatgg
     8341 ctatggttat agccattatg gatactctta cagcgataaa aaataatatt aatgccgggg
     8401 ttccggcatt aatacaactt gaatcgagaa aagatgaaag cttatattgc tatacctaca
     8461 tttaatggca gtgatgtttg gaaacaagca gctaggaata taaaaaaata ctcacccgat
     8521 gggatcttag ttcaaattat tgactcaggt agtaaagatg aaacagttga agtggctcta
     8581 agcaatggat tcaaagtcta tagtattaac ccagcggatt ttaatcatgg aggaacaaga
     8641 aatttagctg ttgaactgca taaagatgaa tatgacatag ttattttcct gacgcaggat
     8701 gctattccag agccggattt ttacgaaaaa atagtaaatg tatttaataa tccattagtc
     8761 tcctgtgcct atggaagaca acttccacat tataatgcaa atcctatatc tcagcatgcg
     8821 aggtatttta attatcctcg ttcaagttat atttcatcca aagctgatat atcgagatta
     8881 ggattaaaaa cagtatttac atctaattca tttgcagcat atcgaatctc aacatttatt
     8941 gaacttgagg gttttcctga tagtaccata ttaagtgagg atatgttttt tgctgcaaaa
     9001 agtataatga caggttatag tgttgcatat gtatctgatg caatcgtccg gcattcacac
     9061 aattattcta cattagaaga gtttaaaaga tatttcgata ttggtgtgtt tcaaacagat
     9121 gaaccatgga ttaagcaaaa ctttggtggt gctggtggag aaggtaaaaa attccttgta
     9181 tctgagatta gatatttact taaaaataat cctatatata ttccggtatc agccatacat
     9241 aactttgcaa aaattttagg atataagtta ggacaaaact ataaaaaaat ccctgtcagc
     9301 gttattaaaa attttagtat gcatagacgt ttttggaact aaatgtagtt atagtattta
     9361 tcacgaaact attttataac atttcgaatt aacgagcgga ataatggcca tgaaaacttt
     9421 taatcatcgc ggacgctcaa agccaaacgc atctttgata tcaatagtac aacgttttac
     9481 agatatatca attatattcg ttggtcttta tgcttcctgc ttaataaata ataaatattt
     9541 tggatataat caaatacttg tatgtttgat cgtgttatcc gcttttcaga tgattggtgg
     9601 tatatcggat ttttatcgct cctggcgcgg cgttaaacta tcagttgaac taagtttagt
     9661 tctaaaaaat tggactttaa gccttcttct aagtatggga ataactactt attctgaagt
     9721 gttaggtttg tcttttaaga tcatgttgga gtggtatttc tttgtttgtt taggcgttgt
     9781 tatttgtcga atgtctatta gggcaggtgc gagatttatt cgtactttgg gctataatac
     9841 gcgaagaatt gcgattgcgg gttcgatgcc tgttgctatt aacttggcaa aaagttttat
     9901 tgatgagcca tggttgggtt ttgttgtagt cgggatttat gacaataaaa tagttaaaaa
     9961 taatgaaata gaatataaag gtgactttaa taagcttatt gttgatgcga aagccggtga
    10021 actagatagg atttacttgg cgatgagtat gagtgatgag attgaaatga gagaacttat
    10081 aagaaattta acgaatacaa cttgttctgt cattttaata cctgatattt ttacctttaa
    10141 tattcttcag tcacgaactg aagaggtgaa tggtgttcct gttgtaccac tttttgatac
    10201 gcctataaat ggtataaata tggtttttaa gcggctggaa gatatatttc tgtcgttatt
    10261 gataataata ctgatatcac caatattatt agttattgct gttgctgtaa aagtttcttc
    10321 acctggtcct gtgatattta aacaaaaaag atatggcatg gatggaaaag caattaaagt
    10381 ctggaagttc cgctcaatga ccgttatgga gaatgatact cttgtaaaac aagcaacaaa
    10441 aaatgatgta cgtgttacta aagttggtag ttttcttcgt aaaacatctc ttgatgaact
    10501 tccccaattt ttcaatgtat taagtggtaa aatgtctatt gttgggccga ggccacatgc
    10561 tgttgcacat aatgaacaat ataggaatat aattgaaggc tatatgctaa ggcataaggt
    10621 taaaccagga attacgggct gggcacaaat aaatggttgg cgtggagaaa cagataccat
    10681 agacaaaatg gagaaaagaa ttgaatatga tctcgaatat attcgcgaat ggagtatatg
    10741 gttagatcta aaaataatat tattaactgt gtttaaagga tttattaata aatcagcata
    10801 ttgatattca tgatcatttg aaaaacttga tttgtgaata tagaagtcgt tcatgaaatt
    10861 ttttattatc tagatcggct agtgttctcc ataaattcag tgaagagaag caaagttgac
    10921 ttattaacga ttgttgaaaa ctgaaagcaa ttgcaggtga tgaacctatt atttcatcaa
    10981 tgctatccat caattcagac aataaaaatc aaccatggtt ggaaataaaa aggatcatcg
    11041 aatgtcgtaa accatatgaa tcggacacct tgattgtaat gggatattaa atctggcggg
    11101 agtcgtttta tccaattgtt tgtgaatgta taatgattaa taaatgcaat atatatcgtt
    11161 tttcaacgaa atacgtaaga tttatccggg ctataatcag accgtaagta ttattttgga
    11221 ttgctaaggt tgttcattca atgtcagtaa aaaactaggc tttatcgacg ttcccttatt
    11281 ttctgcctta ctgcccaatc tgaggccaat agcgtgaata ttggagttaa cgaactagta
    11341 tgtcttgaat aatcgatgct tcagcatagt aagagagttc attgtgcaat tagattttta
    11401 atcatagtgg attcactatt acctataagt gctttaatct gcatttgagg tttcttggat
    11461 atacctgtca agaaacatac tggctatctt attaaatatg ttagtgggag gggatatgaa
    11521 tattagtcag ccattagtta caatttatat atcaacatat aatcggctgg aaaaactcaa
    11581 aagagcaatt aattcagttt tacaacaaga ttacactaac tgggaattga ttgtatgtga
    11641 tgatgcttca tgtgatggaa catcagatta tatgaatgat atttgtatga aagattcacg
    11701 gatcagatat cttcgcaatg atgtgaataa aggtgcttgt gaaacacgaa atttaggcat
    11761 ttttaatgcc aaaggaacct ttatcaccgg tcttgatgat gacgatgaat ttacaaatga
    11821 tcgcatttca ttttttatag ataattggag tgatgagtat tcctttttat gctgtaattt
    11881 caaaaataga tatgtcgata ataatgatct tatccattat aaatgtaact ctaaagattt
    11941 tttattgctt tcatataaag acttgctttt tgataataca gcttcgaatc agatatttac
    12001 tttaacagct aggctccaag agataggtgg cttcgataaa agagttaaaa gactacagga
    12061 ttgggatact tggttacgat tatcatttaa atttggtgag tttataagat ttaataaggc
    12121 cacctatatt atgcaccatg atcatcatat tagcgaatta agggtttcac aaaatgaaat
    12181 aattacaaaa tctcttttag atttggcttt gagaaataaa gaaatatatt ccgatgagga
    12241 ttttttattc atgaatttta ttattgatca aaagaataat aatgcatcac tttatgatgg
    12301 gatctattgg tcctataaga aaagaaatcc taaacatttt ttaaaatata tggttaaaat
    12361 ttttaggtga tttttaattt gtattaatat ttatcatttt aatcttatgg tattaaggga
    12421 ggtttgtgat gtcaattgga aatatatttg caattatagt gacgtataat ccacaattag
    12481 ataaagttaa gaagttggct ttatcgctga agcaacaaaa tgttaaccca ttaattatag
    12541 ataacggcac attgggagag aatgatttag aatctttcag aaatatagca catgtgattt
    12601 tgcttggtaa taatgaagga attgccaaag ctcaaaatat tggtattcgc tttgccaagg
    12661 agaatgcagc tgatggtgtt atctttttcg atcaggatag tgaaataagt gataattttg
    12721 ttgagtcttt gatcagtgat tatatgtctg ttagtaagta cgacaacact attggtatga
    12781 taggaccaac gtttatagat tctcgatata aattttatta taaacagatt ttgctaaatc
    12841 gttttggagt aagaaaaaaa atcgatcctg caaagttatc tactccgttc aaagtaagta
    12901 ttattatttc ttctggttca tttgttctta tgcctatact tgattcagta ggatatatgg
    12961 atgagcgatt ttttattgat tatgttgata ctgaatggtg tttcagaatg ttgtcaaaag
    13021 gttattctat atatgtatca acatcggcta ctatggagca tgccataggt gataagatga
    13081 taaacttttg gggactacat attcctgtac actcgcctgt aagacgttat tatagaatac
    13141 gtaatgcaat tattttctta aattacaaac atattcctct tttattaaag ttaagagata
    13201 atgctatgaa tatcattcat caaagtttaa ttattataaa tgaaaaagat aagcaggaaa
    13261 attttaaaat agcatataaa tctattattg atggtcttaa aggaaaaaca ggtaaattgt
    13321 aaaccaaaat ttaatgtgca atatgtaaca ctgatggtga atgaagatga agacattata
    13381 gtgttatcac gattcttaat taatctaata ttaagatata ttgtcttttc ccaaaaaact
    13441 ctaaaggaat tcaaataaaa aattataaaa tttctgcctt aatcaaatgc attcactcat
    13501 agtttgtagt gtggctaatt ttataataat attgttcttc ggtgctaatt aaattcgtat
    13561 tgttcattat tagtaggtta cattaaatgt atatcctcgt tgcccatcaa tcgtgagtta
    13621 tgtaatgtgc ctattgcgct gcatatgcct tttactgatg tttggcatat tgagcaaata
    13681 taacacctat atgatagatg cagtacgggt aggtaaagga gacagtatta atttttgatc
    13741 tgtatggata gtggtgcact atccgagtct gcctcaagga ggtgtccgta taaataatta
    13801 gaagctctcg cttaattcga gacttctttt ccttggcgaa cgagataagt gctgatatag
    13861 ttatggtatt atatgaccaa aaaatgagaa tatgaaaaac ttatatttga atccgttata
    13921 cttatttggc tatgcatttc tagctgcaat ggggatgtat gctcttagtc tttccggtct
    13981 atacgtcaat ggagattcta cattaactat tacattgttt atattatcca tactttctct
    14041 tatgctaggg tttatattta actctatttt tggaacgaag atgaactctg accttaaggg
    14101 ggaatatgat aaattcctta ctccaaacta catttttatg ttgtttggtt ttcttgttga
    14161 ctgtttagct agtggtgccg tgccattagt taatatatta cgcggagaac tctatgaata
    14221 taaagatttt ggcttgaaaa cttttcatgt attttatatg gcatatatgt cagcatttgc
    14281 aatagtgtct tttgagcgtt atttcattac aaaaaataaa aaatttcttc ttccagtatt
    14341 gactggattg gcaataacaa tatttattgt aagtcgagga gctacaatgc ttttggttat
    14401 gccgatggca ttgctgtacc tttcccagaa aaaagcaggt aaaaaaacag gtaagattaa
    14461 aaagaatttt actattataa ctgtggtgtt aatatttatt atagggtttg gttatattgg
    14521 tgataaaagg atgatagcat ctggatataa aagtgatacc gcaattatgg agataggcca
    14581 ggcaaatgat attttctatt ctataccttc aggttttttt tgggtttatt tatatgcatc
    14641 gtctccatat gcgaatctag catcccagga aagatttgct aatgtagata agggggatct
    14701 agaagacttc tttgcatctt cggttcttcc agattttata agtaaatata ccgctcctta
    14761 tgtgtttact aaatttcaac cgaaaaggat tactgaggaa cttacagttg gtaccggatt
    14821 tagttttgcc ttagttagct ttggtatagt tggtgttata ctattatatt tttggatggt
    14881 ttttctttct tttttcttgg cgtgggcaaa tagaaatatg tacataaatt caatttgtgc
    14941 tgtattgtcg tcaacggcag tactcatgat atttgataat atgtttatat ttgcatcatg
    15001 tgtgttacaa atgcttatgt taacaatatt tacaagagtt aaaattggga aatactattt
    15061 tatgtaatat tattggatat ttattcattt aagatatatc ctcttttatg ttgaagaata
    15121 gtcatactga aaacagaagg gggcataatg gaaagacgta agttcgtagt ttcggcactc
    15181 agcgcggtgg ctgttactta tgctggacat acaaaagcaa gtgagcaccg taatacagat
    15241 ttatcattgt caaagtcagt ggataatata aatattttac tgaaagaaaa caaaattaaa
    15301 aaatccctaa atttagaacc tgaaggtgaa ggtataccgc tcacagactg gatattgggt
    15361 aatattcgat cgctctttct ttatttgaca aaagataaaa tcgattctat caatgctgct
    15421 ataccagttg atgtaaccac tgaattaaat tctgctatgc aggataatat tccgatattt
    15481 atcccgagtg gtaattatat tataactagc tcaataaatg ttggaataag atctggcctt
    15541 ataggcgcag gagcaaagag tgtattaatt gataacagaa gtagtgacca tgcttttata
    15601 ttccctgttg gatatgaccg aggaacaaaa gactttctcg gatttagtat cgaaagctct
    15661 ataggtactg caaaagataa atatgctttc tatttaagtt cagcagcaga cggccgatta
    15721 aattattcag ttggttggag attcgttggt attgaaatta atggtcaggg aatgggaggt
    15781 gggtggtatc ttcaggactg ttttagggtt accatacgcg attgtggagc ttcttctctt
    15841 tcaaatcctt tttaccttgc aggaagtgtg gttcagttga cagtagataa tttcgtcaac
    15901 aatggagaca atcaacctaa gacaaatata ggcagttatg gtgtgtacat gactactaaa
    15961 aaatactctg atgaaaatgg aatcaaaatg cctgaaggta tcactttcat aaattgcaaa
    16021 tttgttaagc aggaggttgg ggctcatgct cttggacttt atgttcaatt tgttaatact
    16081 gaatttgatt actcttcaaa gtttggcgga ttttatgctg gaggtgataa agtcgatttc
    16141 ataaattgct acgtaggcac aacgcatgtt cgtaataatg attttgtggc atttatggtg
    16201 caggctcatg cttcaaaggt tccagaacct gtactaatct ctaattgtac tataaatatg
    16261 caaaagaata gttctgacgg ttataaatct tatggagtta tcctttcagg agagaaagat
    16321 ttcatttctg gtgctaaagt ggttgattgt ttttttagag gggatggcta tgagaattgc
    16381 attctggtta aacgcgttga tggtgtgatt attgaccaca acacttttaa agtaaggggg
    16441 gaaaatgtga aggtagaatc agctaaaaat attactataa gtaataactt tgccttagga
    16501 aactatagtc ttcctaaccc cgaaccagat tactgctgga taataactgg taatactggt
    16561 gatttctctg atgttgattt aagtgaggca aaaaaatctt taatagtcaa tcaaggatta
    16621 atgcgtaatt aactttgtat cttcgctgcc tctcattaat atgaggcaag cgaagtaaga
    16681 gaaaatgtaa ctggctgtag ctatattatg ttagctttct aacattttga atttcctttc
    16741 gaaaatcgga acggtataaa tggaactatc ttctagactg aatcctagag gattccatta
    16801 agacatttcg ttccactgac agttaggtta tcgctattgt caatcagact aaagccgtgg
    16861 tacccgttca tgagcttttt tataaagatg taaaaataat caatgacata ctatatagct
    16921 taaaaaatag tggatccttt tgagtttact cagacctggt ttagcatttt gctcaatcgc
    16981 caaaaactac aaattactaa catataagat ccactagaat tatgtgtgcc tagaattaat
    17041 ttattcaata aagtcaacga taatgctacc gattacctgt atgcatctct ttttctcaca
    17101 ataatcttct ctcctactat ctgaagagca agaataaagc ctatctcggt aggcattgct
    17161 ggagcaaaca gttttggatt ggacagcgcg cagaaactga aggtaaaagt agaatgtgag
    17221 gattttgctt actgctcaag gctgaaatga caaatgaaat agtcctaatg gataagctca
    17281 aaatcattat catggatagt gggcgactgt tttgagaatt atagaaagga gtatattctt
    17341 gaataaaaaa atactatcca attcagtttg gatgatgtct gaaaaaataa ttactttatt
    17401 tggattgata tttgttactt cttttgttgc taaatatgtt ggcaccgagg tttttgggca
    17461 gatagcattt gccacatctt tatttcagat tgcgatgata atagcccagt taggaagtga
    17521 tgttattata tttaaacgtg taagtaaaaa taataagtca ggtgctcggc tcatatctgc
    17581 cactctttat cttaggtcct ttatttattt ttttgctgcc gtcccgatag tatttattag
    17641 ttatgaaaag aatgatgtgg gtagtatcta ctttattatt gcttgcgcaa tatcttgttt
    17701 ttttagcgcg atggatgttt ttagtatata ttatgatgct agattagaat ctagaaaaaa
    17761 caccgttgta aatgttgtag gtttaatcgt cagccttttt tttcgatggc ttattgcttt
    17821 ttttcatctc gatcccattt acttatcttt tcctatcata ctgacaggtt ttattccttt
    17881 tattctaagg tgggctattt ttagaaaaga actcgttaga aataaattaa atgcacgatg
    17941 taaaattaaa tatatgaagt atttgattgg cgctgggatt actttcgttg tatctacaat
    18001 atcggttgca atatatacac gaatatcaat gctatcgctt gggtattttt atgataaatc
    18061 attagtcggt attttttctg tgtctgtgtc tttagctaca tcttggtctt ttgtttgtaa
    18121 ttctttaata acgtcctcat tgccatctat tttttctgaa aagaatgatg ctcaggcaac
    18181 attaaaagct tcaaggttaa atactataat tatagcttgt agcatgccaa taattttgct
    18241 gacttatttg tttggttcgt tctttattag ggtattatat gggggggatt atgttagtgc
    18301 attcactcct ttggttattc tatctttttc aactatgata tcttcgcttg gaataatttc
    18361 tgctcgattt attgctagat tttctgggta tacttttcta tcaaaaaaaa tgttatcagt
    18421 tgtgattttt agttttatta ttaatattcc tttaatttat tactatggta tgttaggagc
    18481 tgctgttgct actcttttga ctgagcttct ctcactcact atatttaact atctatttag
    18541 gcgtggtatt gttctaaaaa tgcatctcat gaccttcttc cctaggcttc ttaagagtcc
    18601 gtaattgatt ttgttaccta tttccttatg ttagtttttt caattttaag atttcatttt
    18661 tgtctatgct ctattgtatt aaatagttta aaatcggatg acacaagctg cgaacatgtc
    18721 gcagtgacca caccagacag gagtatgtaa tgtccaagca acagatcggg gttgtcggta
    18781 tggcagtgat ggggcgcaac cttgcgctca acatcgaaag ccgtggttat accgtctctg
    18841 ttttcaaccg ctcccgtgaa aagaccgaag aagtgattgc cgaaaatcca ggcaagaaac
    18901 tggtcccgta ctataccgtg caagagtttg ttgaatccct cgaaactcca cgccgcatcc
    18961 tgttaatggt gaaagcgggc gcaggtaccg acagcgcgat cgattccctt aagccgtatc
    19021 tggataaagg cgacatcatc atcgatggtg gcaacacctt cttccaggac accatccgtc
    19081 gtaaccgtga gctgtctgcc gaaggtttca actttatcgg taccggtgtt tctggtgggg
    19141 aagagggcgc actgaaaggt ccttctatca tgcccggtgg gcagaaggaa gcttatgagc
    19201 tggtagcgcc aattctcgag aaaatttctg ctcgtgctga agatggtgaa ccatgtgttg
    19261 cctatatcgg tgctgacggt gcgggtcact atgtcaaaat ggtccacaac ggtatcgaat
    19321 atggcgacat gcagctgatt gctgaagcct atgctttact gaaaggtggt ctggctcttt
    19381 ctaacgaaga actggcggca acctttaccg aatggaatgc aggtgagctc agcagctatc
    19441 tgatcgatat caccaaagac atcttcacta aaaaagatga agaaggtaaa tacctggttg
    19501 acgtgattct tgatgaagca gccaacaaag gtaccggtaa atggaccagc cagagttcac
    19561 tggatctggg cgaaccgctg tctctgatta ccgagtccgt tttcgctcgt tatatctctt
    19621 cgctgaaaga tcagcgtgtt gctgcttcta aagtattgac tggtccgcaa gctcaactgg
    19681 ctggtgacaa ggctgagttt gtagagaaag ttcgccgcgc tttatatctg ggcaagatcg
    19741 tttcttatgc tcaaggcttc tcccaattgc gtgctgcatc tgacgaatac aactgggatc
    19801 tgaactacgg tgagattgcc aaaatcttcc gtgccggttg catcattcgt gcgcagttcc
    19861 tgcagaagat cactgatgct tacgagcaga atgcaagcat tgctaacctg ctgctggcgc
    19921 cgtacttcaa acagattgct gatgagtacc agcaggcgct gcgtgatgtc gtggcttatg
    19981 ctgttcagaa cggtatcccg gttccgacat tctctgctgc cattgcctac tacgacagct
    20041 atcgctctgc agtcctgcca gctaacctga tccaggctca gcgcgactat ttcggtgctc
    20101 atacctataa acgcactgat aaagaaggtg tattccatac cgagtggatg gagtaattcc
    20161 attctgcttt aatcctgggg gaatacccca ggattttcgg attattattc tataaacata
    20221 agcgttccct tatattttag cgttaaatgt tagtaatttt ataatttgac tatactctat
    20281 tctgaatata tttcttgatg cagcagtctg agtaaggcta gtgtattaaa tttaatatac
    20341 tgagctttta taactattaa cttgaagtct gtatttaaca ttaaaggtag attaaatatg
    20401 aagatccttg tcactggcgg cgcgggtttt attggttctg cagttgtacg tcatattatt
    20461 gaaaataccc aggacgaagt acgcgtgatg gattgcctga cttatgcggg gaatcttgaa
    20521 tctctggcga cggttgccga tagcgaacgt tactccttta ctcagacgga tatcaccgat
    20581 gctaaatccg tctcggagca gttcagcgat ttccgtccgg atatcgtgat gcacctggcg
    20641 gcagaaagcc atgtcgaccg ctcaattgat ggtccggcag cctttattca gactaacctg
    20701 atcggcacct ttaccctgct ggaggcggca cgtcactatt actctaccct ggatgccgcg
    20761 cagaagcagg cgttccgttt ccaccatatc tctactgatg aagtttatgg tgacctgcac
    20821 ggcactgatg acctgtttac ggaagaaacg ccgtatgcgc caagcagccc gtactctgcc
    20881 tccaaggccg gtagcgatca cctggttcgt gcctggaacc gtacctacgg tctgccggtc
    20941 gtggtgacca actgctccaa taactatggc ccgtatcact tcccggaaaa actgatcccg
    21001 ctgaccattc tcaatgcgct ggcgggtaaa ccgctgccgg tgtatggcaa cggcgaacag
    21061 attcgtgact ggctctatgt ggaagatcac gcgcgtgcac tttataaagt cgccaccgag
    21121 ggcgagagcg gtgaaactta caacattggc ggccataacg aacgtaagaa tattgatgta
    21181 gtacgtacta tctgcgccat tctcgataaa gtcgtagagc agaagccggg caacatcagc
    21241 cagtttgccg atctcatcac ctttgtgaaa gatcgtccgg gccatgatct gcgctatgcg
    21301 atcgatgcgg caaaaattca gcgcgatctg ggctgggtac cacaggagac gttcgagagc
    21361 gggattgaaa aaaccgtgca ctggtatttg aacaaccaga cctggtggca gcgcgtgctg
    21421 gacggctcct atgccggtga gcgccttggc ctcaataact gatatctgac tgattaagga
    21481 atagatttat gaaaggtatt gttctggccg gcggctccgg cacgcgttta tatccgatca
    21541 cccagggcgt ctccaagcag ctgctgccga tctatgacaa gccgatgatt ttctacccgg
    21601 tgtccgtcct gatgctcgcg ggcattcgcg acatcctgat catctccacc ccggacgaca
    21661 tgccttcctt ccagcgcctg ctgggtgacg gatcgcagtt cggggtgaac ttcagctacg
    21721 ccatccagcc gtcgccggac ggcctggcgc aggcctttat cattggtgag aagttcatcg
    21781 gcaacgatgc ctgcgccctg gtgctggggg ataatatcta ctttggccag agcttcggta
    21841 aaaaactgga agcggcggcg gcgaagacct ccggtgccac ggtgtttggt tatcaggtgc
    21901 tggatccgga gcgtttcggg gtggtggagt tcgacgagaa ctttaaggcg ctgtccatcg
    21961 aggagaaacc gctgaagccg aaatcggact gggcggtgac cgggctctac ttctacgaca
    22021 acaatgtggt ggagatggcg aaggacgtca agccttctga acgcggcgag ctggaaatta
    22081 ccactttgaa ccagatgtat ctggagcgcg gcgatttgca ggtggaactg ctggggcgcg
    22141 gatttgcctg gctggatacg ggcacccatg acagcctgat tgaagcttct cagtttattc
    22201 ataccattga gaagcgccag gggatgaagg tcgcctgtct ggaagagata gcctatcgta
    22261 atcagtggct gtcggcggaa ggggtggcgg ctcaggcgga gcgtctgaag aaaaccgagt
    22321 acggtgctta tctcaagcgc ctgctgaacg agcgttaatg ccttcttcgt caacgacagg
    22381 atacagagaa tgaagatttt actgattggc aagaatggcc aggtgggctg ggagctgcag
    22441 cgttccctgt ccaccctcgg cgacgtggtc gcggtggatt attttgataa agagctgtgc
    22501 ggtgacctga cgaatctgga cggtatcgcg cagacggtgc gtatcgtccg cccggatgtg
    22561 gtggtgaatg ccgccgcgca cacggcagtg gacaaggccg aaagcgagcg ggagctctcc
    22621 gatctgctga acgacaaagg ggtggcggtg ctggcggcgg agtcggcgaa gctgggtgcc
    22681 ctgatggtgc actattccac ggactatgtg ttcgacggcg ccggcagcca ttaccgccgg
    22741 gaagatgagg caacaggccc gctgaacgtc tacggtgaaa ccaaacgtgc cggtgaactg
    22801 gcgctggagc agggcaaccc gcgtcacctg attttccgta ccagctgggt gtatgccacc
    22861 cgcggcgcca actttgccaa aacgatgctc cgcctggcgg gtgagaaaga gacgctctcc
    22921 atcattgacg accagcacgg ggcgcccacc ggcgcagagc tgctagcaga ctgcacggcg
    22981 acggcaatcc gtgaaacgct gcgtgatccg gcgctggccg gtacctatca tctggtggcc
    23041 agcggcgaga ccagctggtg cgactacgcc cgctatgtgt ttgaggtggc gagagcgcac
    23101 ggtgccgagc tggcggttca ggaagtgaag ggcatcccga cgacggccta tccgacgccg
    23161 gcgaagcgtc cgctcaactc tcgcctgtcg aatgaaaaat tccagcaggc atttggggtg
    23221 actctcccgg actggcgtca gggtgtggct cgcgtggtaa cagaagtcct gggtaaataa
    23281 acaggtggca aaagatgaac attattaaaa cagatattcc tgaggtgctg atttttgaac
    23341 cgcgcgtgtt tggtgatgcg cggggtttct tctttgagag cttcagcagc aaggtgttca
    23401 atgaggcggt gggccgccag gtggaattcg tccaggacaa ccactcccag tcccagaaag
    23461 gcgtattgcg ggggctgcac tatcagctgg atccgcacgc tcagggcaaa ctggtccgct
    23521 gcgtggaagg tgaggtattt gacgtggcgg tggatatccg tcgttcatcg ccaacctttg
    23581 gcaaatgggt gggcgcggtg ctcagcgcag agaataaacg tcagctgtgg atcccggaag
    23641 ggttcgccca cgggtttatg gcgctgagcg acacggtgca gtttgtctac aaggcgacga
    23701 actactacgc gccacagtca gagcggagca tcatctggaa cgatccggag atagggattg
    23761 actggccggc gctgggcgac tgcgcgctgt cgctgtcgga gaaagatctg caggcacata
    23821 ctctggccac tgcagaagta tataaataat taggttgttt tttcctaaaa tggcgggttc
    23881 caaatggaac tcgtcatgtt tattcgttta caagccgggt caaccaaccg acttgactta
    23941 ccttccttct cagcgtaaaa ccgcccacag cattattaaa attcgtggct atccgccatt
    24001 acccagttaa ctgattaaag tgtaatcgaa tgaaaattac tatttccggt acaggttatg
    24061 ttggtttatc gaacggtgtc ctgattgcgc aaaaccacga agtggtggcc ctggatatcg
    24121 tacaggccaa agtggatatg cttaaccaga agatctctcc gattgtcgat aaagagattc
    24181 aggaatatct ggcagaaaaa ccgttaaatt tccgtgccac cacggataag cacgacgcat
    24241 accgtaatgc cgactacgtg attattgcca cgccgaccga ctacgatccc aaaaccaact
    24301 acttcaacac ctcttaacgg ggtga
//
