LOCUS       AB924583               25094 bp    DNA     linear   BCT 28-OCT-2015
DEFINITION  Klebsiella sp. 5281 DNA, capsular polysaccharide synthesis gene
            cluster, serotype: K46.
ACCESSION   AB924583
VERSION     AB924583.1
KEYWORDS    .
SOURCE      Klebsiella sp. 5281
  ORGANISM  Klebsiella sp. 5281
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella.
REFERENCE   1
  AUTHORS   Pan,Y.J., Lin,T.L., Chen,C.T., Chen,Y.Y., Hsieh,P.F., Hsu,C.R.,
            Wu,M.C. and Wang,J.T.
  TITLE     Genetic analysis of capsular polysaccharide synthesis gene clusters
            in 79 capsular types of Klebsiella spp
  JOURNAL   Sci Rep 5, 15573 (2015)
   PUBMED   26493302
  REMARK    DOI:10.1038/srep15573
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25094)
  AUTHORS   Pan,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2014) Contact:Yi-Jiun Pan National Taiwan
            University College of Medicine, Department of Microbiology; 1, Sec
            1, Jen-Ai Rd., Taipei 100, Taiwan
FEATURES             Location/Qualifiers
     source          1..25094
                     /organism="Klebsiella sp. 5281"
                     /mol_type="genomic DNA"
                     /strain="5281"
                     /serotype="K46"
                     /db_xref="taxon:1497820"
     gene            199..1101
                     /gene="galF"
     CDS             199..1101
                     /gene="galF"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose pyrophosphorylase"
                     /protein_id="BAT23851.1"
                     /translation="MNMNMANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVT
                     IMNVRQAQPLGLGHSILCARPVVGDNPFVVVLPDIILDGGTADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGR
                     YVLSADIWAELERTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQA
                     FVTYGMRNLKEGAKFRESIKKLLA"
     gene            1494..2123
                     /gene="cpsACP"
     CDS             1494..2123
                     /gene="cpsACP"
                     /note="orf2"
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase homologue"
                     /protein_id="BAT23852.1"
                     /translation="MNWQLISFFGDSTVLLPSAAALFIVLMLRKTSRLLAWQWSLLFG
                     ITGAIVCASKLAFMGWGLGIRELDYTGFSGHSALSAAFWPIFLWLLSARFSVGLRKAA
                     VITGYVLAAVVGYSRLVIHAHSVSEVIAGLLLGAAGSALFLLLQKCTSDCDYKTIPWG
                     GIACLVMVPLILLYSGSKAPTQTLLGQIATAIGPLDKPFTREDLHKQAW"
     gene            3003..4523
                     /gene="wzi"
     CDS             3003..4523
                     /gene="wzi"
                     /codon_start=1
                     /transl_table=11
                     /product="surface assembly of capsule"
                     /protein_id="BAT23853.1"
                     /translation="MPRALSILVFPSFSLRYDSGAENGSCTMIKIARIAVTLGLLSSL
                     GAQAYAAGLVVNDNDLRNDLAWLSDRGVIHLSLSTWPLSQEEIARALKKAKPSYSSEQ
                     VVLARINQRLSALKADFRVTGYTSTDQPGTPQGFGQTQPADNSLGLAFNNSGEWWDIH
                     LQGNVEGGERISNGSRFNANGAYGAVKFWNQWLSFGQVPQWWGPGYEGSLIRGDAMRP
                     MTGFLMQRAEQAAPETWWLRWVGPWQYQISASQMNQYTAVPHAKIIGGRFTFSPFQSL
                     ELGASRIMQWGGEGRPESLSNFWDGLTGKDNTAANDPNEPGNQLAGFDFKFKLEPTLG
                     WPVSFYGQMIGEDESGFLPSANMFLGGIEGHHGWGKNAVNWYVEAHDTRTNMSRTNYS
                     YTHHIYKDGYYQQGYPLGDAMGGDGQLVAGKVELITEDNQRWSTRLVYAKVNPENQSI
                     NKAFPHADTLKGVQLGWSGDVYQSVRLNTSLWYTNANNSDSDDIGASAGIDIPFSL"
     gene            4669..5805
                     /gene="wza"
     CDS             4669..5805
                     /gene="wza"
                     /codon_start=1
                     /transl_table=11
                     /product="putative capsule polysaccharide export protein"
                     /protein_id="BAT23854.1"
                     /translation="MNKKIVRFSALALAIGFLSGCTIIPGQGLNNLRKNVVELPDSDY
                     DLDKLVNVYPMTPGLIDQLRPEIVLARPNPQLDNLLRSYEYRIGVGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNSDGTIFYPYIGKVQVAGKTLSQVRQDIANRLTTYIESPQ
                     VDVSVAAFRSQKVYVTGEVTKSGQQPITNIPLTVMDAINAAGGLAPDADWRNVVLTHN
                     GKDTKISLYALMQKGDLTQNHMLYPGDILFVPRNDDLKVFVMGEVGKQSTLKMDRSGM
                     TLAEAIGNAEGMSQAYSDATGVFVIRQLKGDKQGKIANIYQLNAQDASAMVLGTEFEL
                     QPYDIVYVTSAPLVRWNRVISQLVPTITGVHDMTETVRYIRTWP"
     gene            5807..6238
                     /gene="wzb"
     CDS             5807..6238
                     /gene="wzb"
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="BAT23855.1"
                     /translation="MFESILVICTGNICRSPIAERILKSLLPSKHIESAGVAALIDHP
                     ADGSAIRVAEKHNLHLDGHVSRQLTSKIASQYDVILVMEQRQIEHVCRIAPEARGKTL
                     LLGHWLAAKEIPDPYRKSDEAFESVYQLIDQCCQIWAEKLV"
     gene            6257..8419
                     /gene="wzc"
     CDS             6257..8419
                     /gene="wzc"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="BAT23856.1"
                     /translation="MTPIVNNKSQQAESDDFDLGRLLGELIDNRKLIISITSAFTVLA
                     VLYTLLATPIYQADALIQVEQKQGNAILNSINQILPNSQPESAPELTLLQSRMILGKT
                     VDDLNLQAQVRKKYFPIIGRGIARLLGEESGSITVGKLYLPQVEGGDAPQVILTVNDE
                     QRYTIAGDDFTLEGKVGQLINEKGISLLIKEINAQPGSEFVITYLNKLKAISNLQDVF
                     NVADQGKDTGMLSLTLTGDNPTLIKNILNSISNNYLAQNVERQAAQDAKSLAFLNEQL
                     PKVRSDLDFAEDKLNAYRKQKDSVDLTMEAKSVLDQIVNVDNQLNELTFKEAEISQLY
                     TKEHPTYKALVEKRKTLQDEKVKLNKRVSSMPSTQQEVLRLSRDVESGRAVYLQLLNR
                     QQELNIAKSSAIGNVRIVDDAVTEPNPVKPKKILIIIIGTILGAFISIGIVLLRMFLL
                     RGIESPEQLEEAGINVYASVPVAEWYKANLVKGNNKRKEPESLLAIENPADLAIEAIR
                     SLRTSLHFAMMEAKNNILMISGASPNAGKTFISTNLAATMASSGKKILFIDADLRKGY
                     VHKILGSDNDNGLSDYLSGRIPLEKMITTVTKGNFDYIPRGQVPPNPAELLMHPRFNV
                     LISHVSKLYDLVIIDTSPILAVTDAAIIGRYVGTTLLVARFEINTTKEILVSIKRFEQ
                     SGVNVKGCILNGMIRKASSYYGYGYNHYGYAYSEKNNK"
     gene            8475..9920
                     /gene="wbaP"
     CDS             8475..9920
                     /gene="wbaP"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23857.1"
                     /translation="MKTEESMKFLQRNFCCIVALAISDFVSFVVSLYLSLWILSQVLT
                     NFQERVPDEQIYGWIALHWLLGVCCVIWFGVRLRHYFYRKTFWFELKEILRTLVIFAV
                     IEIAVIAFAKWYFSRYVWLLTWLFSFLLVPLFRIGTKYLLDKLGFWLRDTWIIGSGKN
                     ASEAYKAINSEKNLGLHVVGFITTSVDGNECLSIRNVANLDVSPEWLETIDKRTQFIV
                     AVEANEGETRNRWLREFMIKGFRYVSVIPTLRGVPLDSTDMSFIFSHEVMIFRVQQNL
                     AKLSSRILKRAFDIIGSLSIIIIISPLLVYISHKVRKDGGPAIYGHERVGKNGRKFKC
                     LKFRSMVINSKEVLENLLIKDNEAREEWEKTFKLKNDPRITKIGHFLRRTSLDELPQL
                     FNVLKGEMSLVGPRPIITEELQRYNEEVDYYLLSKPGMTGLWQVSGRSDVDYDTRVYL
                     DSWYVKNWSMWNDIAILFKTIAVVLNRDGAY"
     gene            9947..11116
                     /gene="wcuD"
     CDS             9947..11116
                     /gene="wcuD"
                     /note="HG19; orf8"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23858.1"
                     /translation="MKVAIINTLYYPYRLGGAEVSVQVLAESLVKRNVEVIVLTLHEG
                     NTLKIDTFNGVKIYYLPLLNCYWPYNSNEHSKIHRLQWHIKDLYNKQMVKLVSSILQD
                     LRPDIVHTNNLSGFSVGVWRVLRKMNIPTVHTTRDYYLFHPNSTLFKNGKNIDPTNFF
                     VRLNVFYKKYMSKDVNAFIGISKYISDFHYKFGFANKGLHGYVYNPVMEPKVTNSNTD
                     RDKITIGYIGRLTSDKGFDDYINIAQKYQHCKFLAAGKPDASEESRDLLKKAKKSSVE
                     ILGYIPVEEFLNKVDAVLLPIKWNEPFGRVVVESALAYKPVYTNYVGGITEISSFFPW
                     VKDIHSFDEQELKCTISSVTQTLRDKQNPFCSEIHVDNYLKIYNEVVKNNKMVKA"
     gene            11113..12321
                     /gene="wzy"
     CDS             11113..12321
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAT23859.1"
                     /translation="MKIDISKIVPQVFLAFILVKAFSGPIGIIFQPLNYVPTLMMLIL
                     MLRRWAIDVMTKPVSLALVILVVLYFIIGIGNFSILQASFGLYIMIPFFYCLTYSKTI
                     SYYVFNGDQKVYFFLFITCCIGIAYVSMFGAPWLGGVINVGGVDKVISRDWTTGGILR
                     NPGFTAASFDAATLLMISSFFIISKYFENKKFVPAFLIFLTSIYFIYLTTTKTTIVTL
                     IVALVLMLTPVFLTRIMVKVIIIVSILFSYFYMIPQLKYETYDPQNTLLMRMYSTWPR
                     AISLLDDSISIFVGKGFGAIGTPAQYFSPKFYSPGDNVLVYMYVICGFVSVILVGLFV
                     FKFLFSRFYDASLAKKYYIICFCIMIGGVTYNLFESVFYSTSLGVLIGFLFNNNVCKL
                     SFNFNRKIIR"
     gene            12318..13553
                     /gene="wcuC"
     CDS             12318..13553
                     /gene="wcuC"
                     /note="HG18; orf10"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAT23860.1"
                     /translation="MRCAMNFNNKLLALFLAQICIVVPPVYAFDIGIHAHAQRYSQNA
                     LQITSNLEKYGFNSIRSDITWEWVEKKPGSFSLSNAAKKNQNLIDTMDKNNHSAMVVL
                     AYGNGNYTPSGYPENEKQIKAFTDYVKYIVTLNKGKVKYYEVWNEWVYKTGIKDRGVN
                     VPSTDIYLKLVKQTYETIKAIDPSAIVVSGTINPTNTRDVMWFDELIKKGILKYLDGV
                     SLHPYSFMHGNKKLRNPTDNFNDVIEYQNHIAQRNNGINVPIYITEMGVPTYDGEGGV
                     TRLDAAIFAFKYTLLAMSNKNIKGIWWYDYSDDGVIRKNKENNFGFFDHYYHPKSSAV
                     AMYELMKLTQGKDISASIINGNVSVTVRNSLDNTKRVILWNDNESNSLSSNESAKIYI
                     NNEIVDSGKKLFVNTPNLY"
     gene            13561..14610
                     /gene="wcuI"
     CDS             13561..14610
                     /gene="wcuI"
                     /note="HG28; orf11"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23861.1"
                     /translation="MLYINGRFLTQQVTGVQRFALEISKELIKVRDDIIFLVPDKELV
                     SSLDGNCNIEVVSGKNGHYWEQLTLPMFLKKKNDPLLLNLCSTAPAFYNNQVVTHHDI
                     TYKRYPKSFSLKFRLLYGWLVPKILTNSKKIITVSNFSKNEISNYFNIDKNKIDVIYN
                     AVGKEFHTITPKLVEKEKPYALAVSSPNYHKNFHGLIDAFLSTEINLTLKIIGGGAAS
                     FKKMNFNNGDDHRIHFLGRVDDDQLIQLYNNAQFFIFPSFYEGFGIPPLEAQACGCPV
                     IASNTASMPEVLEQSVLYFSPHSKQEMQNALLEINNNAELRATLKNLGDKNSHRFSWK
                     HSAEKINLLLEELEK"
     gene            14612..15721
                     /gene="wcuF"
     CDS             14612..15721
                     /gene="wcuF"
                     /note="HG23; orf12"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23862.1"
                     /translation="MKVLHVAEVIKGGVSSVMNELLLSQIKNDNIERVRCLIPDSQRD
                     ELSIGDSHIYTFKRNGRNLLSFICFVWMFIRTVIKEKPTIIHLHSTFAGLFGRAVLIL
                     LPFYKGRVIYCPHAFSFMMAKSKWKLNLFALVERFLSKFTDAIICVSNYEKEIAIVNG
                     IPKEKLFTIYNGVSEVEYTDQLPKSDSFNILYVGRFDYQKGFDRLENIINGLNYSSSN
                     IKFTIIGDYVSESIDKNRKNLDNANFTGWLSKNKIYSYYHNADLLIIPSRWEGLAMVP
                     LEAFSCKLPVIASSCTSFPEIIKDRYNGFLVDMDNTEVVIQLLNEISADKNIDFLESL
                     ASNAYATYVEKFSSTKMNEDVFNLYRMSKLSADLN"
     gene            15746..16747
                     /gene="wcuV"
     CDS             15746..16747
                     /gene="wcuV"
                     /note="HG53; orf13"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23863.1"
                     /translation="MKKNVFYYPYDSGVNKYAERIRLILSGFSKVMPLNIKEELYFFL
                     TFKKKRGGVAIVNWIENMIITDKSRKISPLGVLKLIISLLVLKYRFDKVIYIQHNLYP
                     HDTFHSHIKIAKWIIEKISLLVHVVAVHSPLFQEKIYIPHPLYEYPLKEINTKNDLTE
                     HNDSYLIFGRIEKYKKIEEIITSFPSSKKLIIAGFCNDKKYEKELSEILLNKENITFI
                     PRYLTDEEASLLFMSCTALIIGHADQDMIVSGSFFYSLTQQLPVLAIKTPFLEWVQSE
                     SKSDILLTFNNIISMMGFIENQKSVFDKKIGFDKKTIDELNSLFGDDYISKIIKTII"
     gene            16772..17581
                     /gene="wclT"
     CDS             16772..17581
                     /gene="wclT"
                     /note="HG116; orf14"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvyl transferase"
                     /protein_id="BAT23864.1"
                     /translation="MFDFILSRKSQEKKCVFWWEPKDGSFNAGDHLSKIVVQQMLALK
                     DLELTQKNNVKNKLMAIGSVMHFANENDCVWGTGINGKISLDALKFKNLDVRAVRGPK
                     TRKLLLDMGLQVPEVYGDPGLLLPFFFSRDTLLINTEPKRDFIVIPHMNEDFSLYKKY
                     NNNICSPKQGAISFTRQIVNSEFVISSSLHGVIIAEAYGIPAVLLENSSGESAFKYDD
                     YYLGTGRDTYPIVHSIEDAFKVKPASSINVRHIALPLFNAFPYDLWDKLKK"
     gene            17699..19183
                     /gene="wzxC"
     CDS             17699..19183
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAT23865.1"
                     /translation="MKNSNESDNLQSDKKSLYSGVAWYFFSNLFPAFSSLLIFSLASR
                     IITPGDLGAVTLAATITTILTSICAVGFGDALIQLRNVEKKHYNTVFFICLISSMFIY
                     FISSLIVEYYVAPTFDVVFKTVYPVIALKIIIDSCAIVPLSFLTRTMAFKSIAIRTMY
                     CSIASIILCLPVLYFGGGVWAIVLSQLSTSVISYIILATSSNLTLRPIFDKSSFSELS
                     RFGITTTFTKLVTSISIDNVIIGVYGSVTTLGIYAFSRRVFGSIADVLNNAIANVSYP
                     LYASVQTKPSQLKNVFFKTTFFSTLLSLPAFTGLIIISPHLIPLIFGTQWIVAIPVIQ
                     VCCVIGFISCIGSLQMSLIKGLGNTAWILKYQIFQQITTALLVFLFARDGALVLILSI
                     AIKTFIIWPYTVYYISRILGVTTFSYISNFIKPFTSVILMYLGCYVIDRELSGSNELW
                     NVLSLIFSGVVIYCVFIFILARKEISESLTAIKKSKKPKVENYE"
     gene            19176..20009
                     /gene="wckQ"
     CDS             19176..20009
                     /gene="wckQ"
                     /note="HG82; orf16"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23866.1"
                     /translation="MNNFTVNFVIPVRHYKSVQDWQSVKSNLEYTLKSIFGQTNDNWH
                     CYIICNRGTDLPKSTNHENVTVLESDFKFISLPNKSVDPEAYHDLIRKDKGARVYEAL
                     KYCKTNDFFMVVDYDDFVHRKIVEFINAMVKKNTEAYFYGWLINVGYIYSGGNVALLN
                     KSFDTICGTSNIVRVCFFEKFYDEYGNLPLLYIKELLGSHRYIKNYMSKAGYSYGSLP
                     FPGAVYNVGISNSSSQTGSVVKEIFSFGKFFKMPRTMIKLWLSIRLFTKKKKRMFNIN
                     C"
     gene            20167..21573
                     /gene="gnd"
     CDS             20167..21573
                     /gene="gnd"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate-6-phosphate dehydrogenase"
                     /protein_id="BAT23867.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESHGYTVSVFNRSREKTEEVIA
                     DNPGKKLVPYYTVQEFVESLETPRRILLMVKAGAGTDSAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILKQIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLALSNEELAQT
                     FTEWNEGELSSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAQNAGIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRTDKEGVFHTEWLE"
     gene            21797..23212
                     /gene="manC"
     CDS             21797..23212
                     /gene="manC"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase"
                     /protein_id="BAT23868.1"
                     /translation="MLLPVIMAGGTGSRLWPMSRELYPKQFLRLFGQNSMLQETITRL
                     SGLEIHEPMVICNEEHRFLVAEQLRQLNKLSNNIILEPVGRNTAPAIALAALQATRHG
                     DDPLMLVLAADHIINNQPVFHDAIRVAEQYADEGHLVTFGIVPNAPETGYGYIQRGVA
                     LTDSAHTPYQVARFVEKPDRERAEAYLASGEYYWNSGMFMFRAKKYLSELAKFRPDIL
                     EACQAAVNAADNGSDFISIPHDIFCECPDESVDYAVMEKTADAVVVGLDADWSDVGSW
                     SALWEVSPKDVQGNVLSGDAWVHNSENCYINSDEKLVAAIGVENLVIVSTKDAVLVMN
                     RERSQDVKKAVEFLKQNQRSEYKRHREIYRPWGRCDVVVQTPRFNVNRITVKPGGAFS
                     MQMHHHRAEHWVILAGTGQVTVNGKQFLLTENQSTFIPIGAEHSLENPGRIPLEVLEI
                     QSGSYLGEDDIIRIKDQYGRC"
     gene            23199..24605
                     /gene="manB"
     CDS             23199..24605
                     /gene="manB"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="BAT23869.1"
                     /translation="MVVANFFGTKRRMTQLTCFKAYDIRGELGEELNEDIAYRIGRAY
                     GEFLKPGKIVVGGDVRLTSESLKLALARGLMDAGTDVLDIGLSGTEEIYFATFHLGVD
                     GGIEVTASHNPMNYNGMKLVRENAKPISGDTGLRDIQRLAEENQFPPVDPARRGTLRQ
                     ISVLKEYVDHLMGYVDLANFTRPLKLVVNSGNGAAGHVIDEVEKRFAAAGAPVTFIKV
                     HHQPDGHFPNGIPNPLLPECRQDTADAVRAHQADMGIAFDGDFDRCFLFDDEASFIEG
                     YYIVGLLAEAFLQKQPGAKIIHDPRLTWNTVDIVTRSGGQPVMSKTGHAFIKERMRQE
                     DAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELLCLKNSSLKSLVADRQAAFPASGEI
                     NRKLGNAAEAIARIRAQYEPAAAHIDTTDGISIEYPEWRFNLRTSNTEPVVRLNVESR
                     ADTALMNAKTEEILALLK"
BASE COUNT     7424 a   4790 c   5594 g   7286 t
ORIGIN
        1 ccgctgaata acctgaacga aaataagatt attctcactt ctgactgttg gtaaaaggga
       61 gttgtgtgta ttcttttacg tgacagtgaa tttaagaatt tggcgggcag atgcccgggc
      121 agtatccgtg tattatcagt ttcaatggat ttgtgacatg tacaattttg caaaaccgcg
      181 tgttttgcaa ccaaacaggt gaatatgaat atggcgaatt tgaaagcggt tattccggtc
      241 gcaggactag gcatgcatat gctgccggcc acaaaggcaa ttccaaagga gatgctgccg
      301 atcgttgata agccaatgat tcagtacatc gttgacgaaa tcgtcgccgc cgggatcaaa
      361 gagattgttc tggtgacgca ctcctcgaag aacgcggtgg aaaaccactt cgacacctcc
      421 tacgagctgg aagccctgct ggaacagcgc gtgaagcgcc agctgctggc ggaagtgcag
      481 gccatttgcc cgccgggcgt gaccatcatg aacgtgcgtc aggcgcagcc gctgggtctg
      541 ggccactcca tcctctgcgc ccgcccggta gtcggcgaca acccgtttgt ggtggtcctg
      601 ccggatatca tccttgacgg cggcaccgct gacccgctgc gctataacct cgccgctatg
      661 atcgcccgct ttaacgagac cggccgcagc caggtgctgg cgaaacgtat gccgggcgat
      721 ctctccgaat actccgtcat ccagaccaaa gagccgatgg tggctgaagg ccaggtggcg
      781 cgtatcgttg agtttattga aaaaccggac gaaccgcaga ccctggactc cgatctgatg
      841 gcggtggggc gctacgtgct gtcggcggat atctgggccg aactggaacg taccgagccg
      901 ggcgcatggg gccgtatcca actgaccgac gccattgccg aactggcgaa gaagcagtcc
      961 gtcgacgcga tgctgatgac cggcgaaagc tacgactgcg ggaagaaaat gggctacatg
     1021 caggccttcg tcacctacgg gatgcgtaac ctgaaagaag gcgccaaatt ccgcgaaagc
     1081 attaaaaaac tgctggcctg agcgccagcc tgaaaccgag cggcaaggct gaagcattcg
     1141 tcctgccgct cataacgtta tgcagaaatt attcataacg cgaatgttat aacgattgta
     1201 aagaaacgta tggcttcgga gacttctggt agtttgtctc tggcctctgt ggtgcaatgg
     1261 tcggagtagc ggcaataatg ctttatgaat agtcacttag tgcgacaatt cctaaagcgc
     1321 agggaaagcg gtcaacgtca gccaaaaata aaacttgact gcgatcatgt ttacgcttta
     1381 aacaactcac ttgcatgcat aaaaatgtga aatgaattgg catgcgagct ggtacagaca
     1441 ttacggataa tccctgagca cggcagtgga catcatcgaa ggatcacagg tatatgaact
     1501 ggcaactcat ctcatttttt ggcgatagca ccgttttgct gcccagcgca gcggcgctgt
     1561 ttattgtcct gatgctgcgt aaaacgtcgc ggttgctggc gtggcagtgg agtttgctgt
     1621 tcggcatcac cggcgctatc gtctgcgcct ccaaactggc ctttatgggc tggggtctgg
     1681 gtattcgcga gctggattac accggcttca gcggccactc cgcgctctcc gcggccttct
     1741 ggcctatctt cctgtggctg ctcagcgccc gtttctccgt cggtctgcgt aaagcggccg
     1801 ttattaccgg ctatgttctg gccgccgtgg tgggctattc gcggctggtc atccatgcgc
     1861 attccgtctc ggaagtgatt gccggcctgc tgctgggcgc tgctggcagc gctttgttcc
     1921 tgctgctgca aaaatgcact tctgactgcg attataagac aataccctgg ggtggaattg
     1981 catgcctggt aatggtccca ctgatactgt tgtatagcgg cagtaaagcg ccgacacaga
     2041 ccctgctggg gcaaatcgcc accgcaattg ggccgctgga taaacctttt accagagagg
     2101 acctgcacaa gcaggcctgg taatcgccgt ttgttttaca ggggaaatta aattttcgcc
     2161 ggttaattag acaaataaga aaataatcta ctatataccc ggtaattgat aattcatatt
     2221 tatgaaataa tgaagtgcta ctacattgtt attgcatatt tgcctggata tagccttgat
     2281 cagacgtttc ttaaatgcgc tgagacgtta cctgatggac attcaatgaa tatccagatt
     2341 caggaaacta ttagaaattg tagttgacta caacgccatc atctgatttt tgcatgttga
     2401 tgagctatgg aaaaagacgt ttttttacag tcagttagct gcatatgtga tgttgtagca
     2461 gtaccgggaa gatctttaac cctggaagcc agtgaataat cttaattggt gacccgctta
     2521 ttttttgtca gtagaacgac aggcggcatt aattggcaga tattcggtaa caacactccc
     2581 aattgtgacc gaaatcccgt aaacttaacg ccgccaaaaa taatggcctg accaattatt
     2641 catccacagg tcgataaaaa aattaagccg ttcaggtagt cagtgcgctg gtagctgtta
     2701 agccaggggc ggtagcgtcg ctgaagccgc ttgctgctgc acagaggttc tcttcaacgg
     2761 ctgaaaaatc gtcccggtca ggatgatcgc cctcaatcga tatctatcaa ttttctacgg
     2821 atatcctcag aagttggcca ggaacggctg ctgatatcgc ctggagatta actttcctgt
     2881 ctcatcgata gcctgtaggg taaaattcgc ctacattgtg agctgagtgg atgttataag
     2941 gctaacaagc agcttagggt aaatgtactt gcctcgccgg tgttgcacag cgaagtcagc
     3001 tggtgccgcg agcgctttct atcttggtat tcccctcatt ctcattgaga tacgacagcg
     3061 gggctgaaaa tggatcttgt acaatgataa aaattgcgcg cattgccgtg acgttgggtt
     3121 tgctttcctc actgggagcc caggcttacg cggccgggtt agtggtaaat gacaacgact
     3181 tgcgtaacga cctggcctgg ctttccgatc gcggggtcat ccatctgagc ctgtcgacgt
     3241 ggccgctgag ccaggaagag atcgcccggg cgctgaaaaa ggccaaacct tcctactctt
     3301 ctgagcaagt ggtgctggcg cgtatcaacc agcgactgtc tgccttaaaa gcggatttcc
     3361 gggtcaccgg ctacacttca accgatcagc cgggcactcc gcaggggttt ggtcagacac
     3421 agccggcgga taactcgtta ggcctggcat tcaacaacag cggcgagtgg tgggatatcc
     3481 atctccaggg caacgttgaa gggggagagc ggatcagcaa cggatcgcgc ttcaacgcca
     3541 acggcgcata cggcgcggtg aagttctgga accagtggct ctcttttggc caggtaccac
     3601 agtggtgggg gcctggctat gaaggtagcc tgattcgcgg ggatgcaatg cgaccgatga
     3661 ccggcttcct gatgcagcgg gcagagcagg cggctccaga gacctggtgg ctgcgctggg
     3721 taggtccatg gcagtaccag atctccgcca gccagatgaa tcaatatacc gcagtacccc
     3781 atgccaaaat aatcggcgga cgtttcacct tttcaccttt ccagtcttta gagttaggcg
     3841 cgtcgcgcat tatgcagtgg ggtggggaag ggcggcctga atcacttagc aacttctggg
     3901 atggtttaac cggtaaagac aataccgccg caaacgatcc caatgaaccg ggcaaccagt
     3961 tggctgggtt cgattttaag ttcaaacttg agccgactct tggctggccg gtgagcttct
     4021 acgggcagat gataggcgag gatgagtcgg gttttctacc ttcggcaaat atgttcctcg
     4081 gcgggatcga agggcaccat ggctggggta agaatgctgt taactggtac gtggaagcac
     4141 atgacacgcg caccaatatg agccgaacca attatagtta tacccatcat atttataagg
     4201 atggctacta tcagcagggc tatccgctgg gtgacgcaat gggcggggat ggccaacttg
     4261 ttgccggtaa agttgagctt attacggagg ataaccagcg ctggagtacg cgcttagtat
     4321 acgcgaaggt taacccggag aatcagtcga tcaacaaagc gttccctcat gcggatactc
     4381 taaaaggtgt acagctgggc tggagcggcg atgtttatca gtcggtccgc ctgaatacct
     4441 cactgtggta caccaacgct aacaacagcg acagcgatga cattggggcc agtgcaggga
     4501 tagatatacc gtttagttta taaggctgaa tgctgaaaat aggggagagg gagtggtagc
     4561 gctgcaggat gcagtcagct tttatctctc cataagccgg caggaaagca acggctatga
     4621 cagctgctca ggaattggca aatcttgttt tactgatgat gtgacattat gaataaaaaa
     4681 attgttagat tttcggcatt agcgttggca attgggtttt tatcgggttg tacaatcatc
     4741 cctggccagg gattaaacaa tctgcgtaag aacgtagtgg agcttccaga cagcgactac
     4801 gatctggaca aactggttaa tgtgtacccg atgacgccgg gcctgatcga ccaactccgt
     4861 ccggagattg tgctcgctcg tccaaaccca cagctagata atttactgcg cagttatgaa
     4921 tatcgcatcg gggttggcga tgtattgatg gtcactgttt gggatcaccc ggaactaacc
     4981 acacctgcag gccagtaccg tagtgccagc gacaccggta actgggttaa ttcagacggt
     5041 accattttct atccttatat tggtaaggta caggtggcgg gtaaaacgtt gagtcaggta
     5101 cgccaggata tagctaaccg tttgaccacc tatattgaga gtcctcaggt cgatgtgagc
     5161 gttgctgctt ttcgttctca aaaggtgtat gtgacaggtg aagtgacaaa atcaggccag
     5221 caacctatta ccaatattcc tttaacggtg atggatgcaa taaatgctgc cggtggactg
     5281 gcaccagacg cagactggcg taatgttgtg ctgactcata atggtaaaga tacaaaaata
     5341 tcattatatg cattgatgca aaaaggggat ttgacacaaa atcatatgtt atatcctggg
     5401 gatattctct ttgtaccacg aaatgatgat cttaaagtgt ttgtcatggg agaggttggc
     5461 aaacagagca cattgaagat ggatcgtagt ggaatgacat tagcggaggc tatcgggaat
     5521 gctgaaggta tgtctcaagc atacagtgac gctacaggag tgtttgtaat tcggcagttg
     5581 aaaggtgata aacaaggtaa aattgctaat atatatcagt tgaacgcgca agatgcttct
     5641 gcgatggtac ttggtacaga atttgaatta caaccttatg atatcgtcta tgtcacatcg
     5701 gctccattag tacgttggaa tcgtgtaatt tcccaactag tacctaccat tactggcgta
     5761 catgatatga ctgaaactgt aagatatata aggacgtggc cataaaatgt ttgaatcgat
     5821 tttggttatt tgtacgggta atatatgtcg ttctcccatt gctgagcgta tcttaaaatc
     5881 acttttgcca agtaaacata ttgaatctgc tggggttgct gcattgatag accatccagc
     5941 agatggttca gcaatacgtg tagctgagaa acataattta caccttgatg gtcatgttag
     6001 taggcagtta acttcaaaga ttgcgagcca atatgatgtt attcttgtta tggaacagag
     6061 acaaatagag catgtttgtc gaattgcacc tgaggcaaga ggaaaaactc tactattagg
     6121 tcactggctg gcagcaaaag aaatcccaga cccatatcgt aaaagcgatg aggcctttga
     6181 atcagtatat caattaatcg accaatgctg ccaaatttgg gcagagaaat tggtataaga
     6241 atttaggaat aactgcatga caccgattgt taataacaaa tctcaacaag ctgaatcaga
     6301 tgattttgat cttggccgat tgttgggtga gcttatcgat aatagaaaac taataatttc
     6361 aattacatca gcttttactg tgttggctgt attatataca cttctggcaa cccctatata
     6421 tcaagctgat gctttgatac aagttgaaca aaaacaaggg aatgcgattc tcaatagtat
     6481 caatcaaata ttaccgaata gtcaaccaga gtcagctcct gaattaaccc tactccagtc
     6541 aagaatgatt ttaggaaaaa cggttgatga tctcaattta caggctcagg taaggaaaaa
     6601 gtattttcct ataattgggc gtgggatcgc aagacttttg ggggaggagt caggttctat
     6661 tacagttgga aaactttatt taccacaagt tgagggagga gatgcccccc aggttatttt
     6721 aactgtaaat gatgaacaaa gatatactat tgctggtgac gattttactc tcgagggcaa
     6781 agttggtcag ttaataaatg aaaaaggtat ttctctatta attaaagaaa ttaatgcaca
     6841 accgggaagt gaatttgtaa ttacctatct taataagttg aaagcaatta gtaacttgca
     6901 ggacgttttt aatgttgccg atcagggtaa agatactggt atgctttcat taacgttgac
     6961 aggtgacaac ccaactttaa taaagaatat tttaaatagc atcagtaata attacttagc
     7021 acaaaatgta gaacgacaag cggcacaaga tgctaaaagc ttagcttttt tgaacgagca
     7081 gttaccgaaa gtaaggagtg accttgattt tgcagaagat aagttaaatg cttatagaaa
     7141 acagaaagac tccgttgact tgacgatgga agcaaagtca gttcttgatc aaattgttaa
     7201 tgttgataat cagttaaatg aattgacatt taaagaagct gaaatatcgc agttatatac
     7261 aaaagagcat cctacatata aagcattagt tgaaaaaagg aaaacacttc aagatgagaa
     7321 agttaaacta aacaaacgtg ttagctccat gccttctacg caacaagaag tattaagatt
     7381 aagccgagat gttgagtctg gcagagcagt ttatttacaa ttattaaatc gacaacaaga
     7441 actcaacatt gcgaaatcga gtgctatagg aaatgttcgc attgtagatg atgcagttac
     7501 tgaacctaac ccagtaaaac ctaaaaagat attaataata ataataggaa caattctggg
     7561 agcatttatt tcgattggca ttgtcttgtt aaggatgttt ttattaagag gtatagaatc
     7621 tccagagcaa ttggaagagg ctggtataaa tgtctatgca agcgttcctg tggctgaatg
     7681 gtataaggca aatttagtaa aaggcaataa taaacgaaaa gaacctgaat cattactggc
     7741 aatagaaaat cctgctgatc tagcaataga agctattaga agcctacgta caagccttca
     7801 ctttgcaatg atggaagcaa aaaataatat attaatgatt tctggggcaa gcccaaatgc
     7861 aggcaaaaca tttataagta cgaatttagc agcaacaatg gcctctagtg ggaaaaagat
     7921 attatttatt gatgctgacc tccgcaaggg ttatgtacat aaaatattgg gttcagataa
     7981 tgacaacgga ttatctgact atttatctgg aagaataccc cttgaaaaga tgattacaac
     8041 tgtcacaaaa ggtaattttg attacattcc tcgcggtcag gttccgccca atcctgccga
     8101 attattgatg catccacgct ttaatgtatt gatttcacat gtatccaagc tttatgattt
     8161 agtgattata gatacctccc ctatattagc agtcacagat gctgcaatta ttggtcgtta
     8221 cgttggtaca actttacttg tggcaagatt tgaaattaat actaccaaag aaatcctcgt
     8281 gagtattaaa cgttttgagc aaagcggcgt gaatgtgaaa ggttgtattc ttaatggtat
     8341 gataagaaag gccagtagtt attatggtta tggttacaac cattatgggt atgcatattc
     8401 cgaaaagaat aataaataag ttatcgggcc ttgttacaca aggcctagtt agtttacttc
     8461 catatgtcga ataaatgaag acagaggaat ctatgaaatt tttgcaaaga aatttttgtt
     8521 gtatagttgc attggcaata tctgattttg ttagttttgt tgtatctcta tatttatcac
     8581 tatggatttt gtcgcaggtg ctcacgaact ttcaagagcg tgttcctgat gagcaaattt
     8641 atggatggat agccctacac tggttgcttg gggtatgctg tgtaatttgg tttggcgtaa
     8701 ggttaagaca ttatttttat cggaagacct tttggtttga attgaaagaa attttgcgaa
     8761 ctttggttat atttgcagtt attgaaatag cggtgatagc attcgcgaaa tggtattttt
     8821 cgaggtatgt ctggctatta acatggctat tctctttctt actggttcct ttatttagaa
     8881 ttgggactaa atatttatta gataaattag gtttttggct tcgggatact tggattatag
     8941 gaagtggtaa aaatgcgagt gaagcatata aggcaataaa tagcgaaaaa aaccttggtc
     9001 tacatgtcgt cggttttata accacatctg ttgatggtaa tgaatgttta tctataagaa
     9061 atgtagcaaa tttagatgtc tcaccagaat ggttagaaac aatagataag agaacgcaat
     9121 tcatagttgc agtagaagct aacgagggag aaacgagaaa tcgttggtta agggagttca
     9181 tgatcaaagg gtttagatat gtctccgtga ttcctaccct tcgaggtgtt cctcttgaca
     9241 gcactgacat gtcttttata ttcagtcatg aagttatgat atttcgtgtg cagcaaaatt
     9301 tagcaaaact ttcctccaga atcctaaaga gggcattcga tattataggc tcattatcaa
     9361 taataattat tatctctccg ctattagtat atattagcca taaagtgaga aaagacggcg
     9421 ggccggctat ttatggtcat gagcgagtag gtaaaaatgg gcgaaagttt aaatgcttga
     9481 agtttcgatc tatggtgata aattctaaag aggtattaga gaatttatta atcaaagata
     9541 atgaagcgag agaagagtgg gaaaaaacat ttaaattaaa aaatgatcca agaattacga
     9601 aaatagggca ttttctcaga agaacgagtc ttgacgaatt accacagctt ttcaatgtcc
     9661 taaaaggcga aatgagcttg gtaggaccac gacccattat cacagaggaa ttacaaaggt
     9721 ataatgagga agtggattat tatcttctta gtaagcctgg tatgacaggg ctttggcaag
     9781 ttagtggcag aagtgatgtt gactacgata cacgagtgta cttggattcg tggtatgtta
     9841 aaaattggtc gatgtggaat gatattgcaa ttttgtttaa aaccattgcc gttgttttaa
     9901 atcgtgatgg agcatactaa aatcttttaa caaataagga aaaacaatga aggttgctat
     9961 tataaataca ttatattatc catatagatt aggtggcgcg gaggtctccg tccaggtttt
    10021 agcagaatct cttgtcaaaa gaaacgttga agtgattgtt ttgacccttc atgaagggaa
    10081 taccttaaaa atagacacat ttaatggtgt gaaaatatat tacttacctc tccttaattg
    10141 ttattggcca tataatagca atgagcacag taaaattcat agattacaat ggcatataaa
    10201 agatctatat aacaagcaaa tggttaaatt agttagtagt attcttcagg atttacgtcc
    10261 tgatatagta cacactaata atctctccgg attttctgtt ggggtgtggc gggttttaag
    10321 aaaaatgaac atcccgacag tgcatactac cagggattat tatctctttc atcccaactc
    10381 aacattattt aaaaatggca aaaacattga cccaacaaat ttctttgtaa gactgaacgt
    10441 tttttataaa aaatatatga gtaaggatgt aaatgctttt ataggaatta gtaaatatat
    10501 atcagatttt cattataaat ttggttttgc taataaagga ctacatggtt atgtttataa
    10561 ccccgttatg gagccgaaag ttacaaacag taacacagat agagataaaa taaccattgg
    10621 gtatattggg aggcttacct cggacaaggg atttgatgat tatattaata ttgctcaaaa
    10681 atatcaacat tgcaaatttt tagctgcagg gaaacctgat gcttcagaag agtcaagaga
    10741 tttattaaaa aaagccaaga aatctagtgt tgaaattctt ggctatattc cagtggaaga
    10801 attcttaaat aaagttgatg cagtattgtt gccaataaaa tggaatgaac cttttggaag
    10861 agttgtcgtt gaaagtgcat tagcatataa accggtttat acgaactatg ttggtggaat
    10921 aacagaaata tcctcatttt ttccatgggt caaagatatt cattcgtttg acgaacaaga
    10981 attgaaatgt actataagtt cagttacgca gactttacgc gacaaacaaa atccattttg
    11041 ttctgaaatt catgttgata actatcttaa aatatataat gaggtagtta aaaataataa
    11101 aatggtaaaa gcatgaaaat agacataagc aaaattgtgc ctcaagtctt tctagcgttt
    11161 atattagtta aagctttttc agggccaatt ggaatcattt ttcaaccatt aaattatgtg
    11221 ccaacgttaa tgatgctaat acttatgctc aggcggtggg caatcgacgt aatgacaaaa
    11281 cctgtatcac tggctttggt catcttagtg gtattgtatt ttataatagg cattgggaat
    11341 tttagtatat tacaagcctc ctttggtttg tatataatga tacctttctt ttattgccta
    11401 acatatagca aaacaatttc ctattatgtg ttcaatggag accagaaagt ttatttcttc
    11461 ttattcatta cttgttgcat tggcattgcc tatgtaagta tgttcggtgc gccatggtta
    11521 ggtggggtaa ttaatgtcgg tggggttgat aaagtcatat ctcgcgattg gacaacaggt
    11581 ggaatattgc gtaaccctgg attcactgcc gcatcttttg atgctgcaac tcttttgatg
    11641 atttcctctt tttttattat ctcaaaatat ttcgaaaata aaaaatttgt gccggccttt
    11701 ttgattttct tgacttcaat ctattttata tatttgacga cgactaaaac tactatagta
    11761 actttaatcg ttgcattggt tttaatgtta actccagttt ttttgactag aataatggtc
    11821 aaagtaatca ttatagtgtc gattttattt agttattttt acatgatacc gcaattaaaa
    11881 tatgaaactt atgatcctca gaatacgctg ttaatgcgca tgtatagtac atggccaaga
    11941 gctatatcgt tgctcgatga tagtatatct atttttgttg gtaaaggttt tggtgcaatc
    12001 ggtactccag ctcaatattt ttctccaaaa ttttacagtc caggggataa tgtattagtt
    12061 tacatgtatg taatttgtgg gtttgttagc gtaattttgg tcggtttgtt cgtttttaaa
    12121 tttttattct caagatttta tgatgcctct ctcgcaaaga aatattacat catttgtttt
    12181 tgcattatga ttggtggagt cacatataac ctttttgaat ccgtttttta ttcaacaagt
    12241 ttgggcgtgc taataggttt tttgtttaat aacaatgtat gtaaactttc ttttaatttc
    12301 aatcgtaaaa ttattagatg aggtgtgcaa tgaatttcaa taataaatta ctggcattgt
    12361 ttcttgcgca aatttgcatt gtagtacctc ctgtttatgc attcgatata ggaatacatg
    12421 cgcatgcgca aaggtactca caaaatgccc tgcaaataac ttctaatttg gaaaaatatg
    12481 gatttaatag tattcgtagt gatattacat gggagtgggt cgaaaaaaaa ccagggagtt
    12541 tttcactgag taacgcagct aaaaaaaacc aaaatttgat tgacaccatg gataagaata
    12601 accatagcgc catggtcgta cttgcatatg gaaacggaaa ctacacgcca tcaggatatc
    12661 ctgaaaatga aaaacagatt aaagctttta cagattacgt taaatatatt gttactttaa
    12721 ataaaggaaa agttaaatat tatgaagtat ggaatgaatg ggtatataaa acaggtataa
    12781 aagatagggg cgtaaatgtt ccctcgacag atatttactt gaagcttgtc aaacaaacat
    12841 acgaaactat aaaagcgata gacccatcag caatagttgt gtctggaacg ataaatccaa
    12901 ccaatacgcg ggatgtgatg tggttcgatg aattaataaa aaaggggata ttgaaatact
    12961 tagatggtgt gtcacttcat ccctattcat ttatgcatgg taataaaaaa ctaagaaatc
    13021 caaccgataa tttcaatgat gtgattgaat atcaaaatca catagctcag agaaataacg
    13081 ggattaatgt gcctatctat ataactgaaa tgggcgtccc tacatatgat ggtgagggtg
    13141 gagtgacccg tttggatgca gcaatatttg cttttaaata tacattacta gccatgtcta
    13201 ataaaaatat aaaaggaatt tggtggtatg attattccga cgacggagtt ataagaaaga
    13261 ataaagaaaa taattttgga ttctttgatc attattatca tccgaaatca tcagcggttg
    13321 ctatgtatga attgatgaaa ctgacacagg gtaaagatat atcagctagc atcattaatg
    13381 gcaatgtttc tgtgactgtc agaaattcat tagataatac gaaacgagta attttatgga
    13441 atgataatga atctaactca ttaagttcta acgagagtgc taaaatttat ataaataatg
    13501 agattgtaga ttcaggcaaa aagctttttg ttaacacacc aaacttatac tgaaggtaat
    13561 atgttatata taaatggtag atttttaacc caacaagtaa ctggtgtcca acgttttgct
    13621 cttgagattt cgaaagagtt aattaaagtt cgtgatgata ttattttctt agttccagat
    13681 aaagaactag tgagttcatt agatggtaat tgcaacatag aagttgtatc tggaaaaaat
    13741 gggcattatt gggaacaact gaccctacct atgtttctaa aaaaaaagaa tgatcctttg
    13801 ctacttaatc tatgtagtac tgcaccagca ttttataata accaagttgt tactcatcat
    13861 gacatcacct ataaaagata tccgaaaagt ttttcattaa aatttagatt attatatggc
    13921 tggttagttc ctaaaattct tacaaattca aagaaaataa taacagttag taacttctca
    13981 aagaatgaga tatcaaacta cttcaacata gataaaaata aaattgatgt tatctataat
    14041 gctgtaggaa aagagttcca tactattaca ccaaagcttg ttgaaaaaga aaaaccatat
    14101 gcattagcag tatcttcacc aaattatcat aaaaactttc atggattaat tgatgccttt
    14161 ctgagtactg aaattaatct aactttaaaa attataggag gaggggctgc aagttttaag
    14221 aaaatgaatt tcaataatgg agatgatcat aggatacatt ttctaggcag agtcgatgat
    14281 gatcaattga ttcagttata taacaatgca cagtttttca tcttcccttc tttttatgaa
    14341 ggttttggaa tacctccatt agaagctcaa gcatgtggat gtcctgtcat agcctctaac
    14401 acagcctcta tgcctgaggt attagaacaa agtgttttat atttttctcc acattcaaaa
    14461 caagaaatgc aaaatgcttt gctggaaata aacaataatg ctgaactaag ggctactctc
    14521 aaaaatttag gagacaagaa tagccatcgt ttttcatgga aacactctgc agaaaaaatt
    14581 aatttattac ttgaagagtt ggaaaaatag aatgaaagta cttcatgttg ctgaagttat
    14641 taaaggagga gtgtcctccg tgatgaatga actacttcta tcacaaatta aaaatgataa
    14701 tattgaaaga gtacgttgtt tgattcctga ttcacaaaga gatgagctta gcattggcga
    14761 ttctcatata tacactttta aacgtaatgg acgtaatcta ttatccttta tatgttttgt
    14821 ttggatgttt attagaactg ttatcaaaga aaaaccgaca ataatacatt tgcatagtac
    14881 gtttgcaggc ttatttggga gagcagtttt gatactttta cctttttata aaggtcgagt
    14941 aatttactgc ccacatgctt tttcattcat gatggcaaag agtaaatgga aattaaattt
    15001 atttgcatta gttgaacgtt ttctttcaaa atttaccgat gctattatat gcgtaagtaa
    15061 ctatgaaaag gaaatagcaa ttgttaacgg tatacctaaa gaaaagttat ttaccatata
    15121 taatggtgtt tctgaagttg aatatactga tcaattaccc aagagtgatt ctttcaatat
    15181 actctatgtt ggtcgctttg attaccaaaa aggttttgat aggctagaga atattattaa
    15241 cggattaaat tattcaagca gtaatatcaa gtttaccata atcggtgact atgtctcaga
    15301 aagcattgat aaaaatagaa aaaatctaga taatgctaat tttacaggct ggttgtctaa
    15361 aaataaaatt tattcatatt atcataatgc agacttatta ataatacctt cccgctggga
    15421 agggctggct atggtacctc ttgaagcatt tagttgtaaa ctcccagtta ttgctagttc
    15481 ctgtacttct tttcctgaaa ttatcaagga tcgatataat ggtttcttag tagacatgga
    15541 taatactgaa gttgttattc aattacttaa tgaaatatcg gctgataaaa atattgactt
    15601 cctcgaaagc cttgcctcta atgcgtatgc aacttatgtt gaaaaattct cttcaacaaa
    15661 aatgaatgaa gatgtattca atttatatcg tatgagcaaa ctgtccgctg atttaaacta
    15721 atgaaataga gtacttggga aaattatgaa aaaaaatgtg ttttattacc cttatgattc
    15781 gggtgttaat aagtacgcag aaagaattcg cttaatatta tcagggtttt caaaggtcat
    15841 gcccttaaat attaaagagg agctttattt ttttttaaca tttaaaaaaa aaagaggggg
    15901 agttgcaatt gtaaattgga ttgagaatat gatcataacc gataaaagtc gaaaaatcag
    15961 tccgttggga gttttaaaac tgattatttc ccttttagta ctcaaatata ggtttgataa
    16021 ggttatatat attcaacata atttatatcc tcatgatact ttccactctc atataaaaat
    16081 tgcaaaatgg attattgaaa aaatttctct tttagttcat gtcgttgcag tccatagtcc
    16141 cttatttcaa gaaaaaatat acatacctca tccattatac gaatatccac ttaaagaaat
    16201 taatacaaag aatgacttga cagaacataa tgattcatat ttgatttttg ggagaataga
    16261 gaaatataaa aaaattgagg aaataattac ctctttcccg tcatccaaaa aattaataat
    16321 tgcaggtttt tgtaacgata aaaaatatga aaaggaatta agtgaaattc ttttaaacaa
    16381 ggagaacatt acttttattc ctcgttattt aactgatgaa gaagcatctt tgttatttat
    16441 gtcatgtaca gcgttaataa tcggacatgc agatcaagac atgatagttt ctggttcatt
    16501 tttttattct ctgacacaac aattaccagt gttggccata aaaacgcctt ttttagaatg
    16561 ggttcaatct gaatcgaaaa gtgatatatt attgactttt aataacatca tttctatgat
    16621 gggatttatt gaaaatcaaa aaagtgtgtt cgataagaaa attgggtttg ataagaaaac
    16681 tattgatgaa ctaaattcat tgtttggaga cgattatatc tctaaaataa taaaaacaat
    16741 tatttaattt aaactaaatg taggaaataa aatgttcgat ttcattttaa gcagaaagtc
    16801 acaagaaaaa aaatgtgtat tttggtggga acctaaagat ggtagtttta atgcaggtga
    16861 tcatttatct aagatcgttg tacaacagat gttagcttta aaggatctcg aactgactca
    16921 aaaaaataat gttaaaaata aattaatggc aattggttcc gttatgcatt tcgctaatga
    16981 aaatgactgt gtatggggga ctgggatcaa tggaaaaatt agtctagatg cattaaaatt
    17041 taagaacctt gatgttagag ctgttcgagg gccaaaaacg cgcaaactat tattagatat
    17101 ggggctccaa gttcctgaag tttatggcga tcctggttta ttattacctt tttttttctc
    17161 acgtgatacg ttattaatca atactgaacc aaaaagggat tttatcgtaa ttccacatat
    17221 gaatgaagac ttttcgttgt ataaaaaata taataataac atttgttctc caaaacaagg
    17281 tgctatatca tttacacgcc aaattgttaa tagtgagttt gttatttcaa gttcattaca
    17341 tggggtaatt atagcagagg cttatggtat tcctgctgtg ttacttgaaa acagtagtgg
    17401 agaatcagca tttaagtatg atgattatta tttaggtact ggacgcgaca cttatcctat
    17461 tgttcatagt atcgaagacg cctttaaggt caaacctgca tcttcaatta atgtccgcca
    17521 tatagctttg cctttattta atgctttccc atacgactta tgggataagt taaaaaaata
    17581 gcgagcttta tgtttaatta aatgcagtac ttaagcaaca gttattaact gattaaatta
    17641 atttacataa cagatattgg tatataacaa tatctgttta acatcactaa gtgcaaaaat
    17701 gaaaaatagt aatgaatcag ataatctaca atctgacaaa aaaagccttt attcaggtgt
    17761 cgcatggtat tttttcagca atttgtttcc agcatttagt tcattattaa tattttcatt
    17821 agcatcaagg atcataacac ctggtgatct aggtgctgta acgttggcag caactataac
    17881 tactatccta accagtattt gtgctgtagg atttggtgat gctctaattc aattaagaaa
    17941 tgtagaaaaa aaacattata acactgtttt ttttatttgt ttaatttctt ccatgttcat
    18001 ttattttata tctagtttaa ttgttgaata ttatgtagcc cctacatttg atgtggtttt
    18061 taaaacggta tacccagtta tagcattgaa aataataata gattcatgcg caattgtacc
    18121 tttgtccttt ttaacacgaa cgatggcttt taaatcaata gcaataagga caatgtattg
    18181 ctctattgca tccattatat tatgcctgcc agtgttatat tttggtggcg gagtttgggc
    18241 cattgtttta agccagttaa gtacatcagt aatcagttac ataatcttag ctacttcttc
    18301 taaccttaca cttagaccta ttttcgataa atcaagcttt agtgaattaa gtcgttttgg
    18361 tataactacg acttttacaa agctcgttac ttcaattagt atagataacg ttattattgg
    18421 tgtgtacggt agtgtcacca ctttaggtat ttatgcattt agtcgtagag tttttggttc
    18481 tattgctgat gttttgaata atgctattgc taatgttagc tatccccttt atgcgtcagt
    18541 gcaaacaaaa ccatcgcaat taaagaacgt tttttttaaa acgacctttt tctcaactct
    18601 attgagctta cctgctttta cgggattaat aataatttct cctcatttga ttccacttat
    18661 attcggaact caatggattg ttgccattcc tgtcattcaa gtttgttgtg taatcggttt
    18721 tatttcatgt attggctcac tgcaaatgtc gcttattaag ggcttgggaa atactgcttg
    18781 gattcttaaa tatcagattt ttcagcagat aacgacagct cttttagttt ttttattcgc
    18841 aagggatggt gcactagtat taattctatc aattgctatt aagactttta tcatatggcc
    18901 ttatactgtt tattatattt ctagaatttt aggggtaact actttttctt atatttctaa
    18961 ttttattaaa cctttcactt ctgttattct gatgtatcta ggttgctatg ttatagacag
    19021 ggaattaagt gggtctaatg agttgtggaa tgtattgtca ttgatttttt cgggtgttgt
    19081 aatatattgt gttttcatat tcatattagc aagaaaagaa atttcagaat ctttaacagc
    19141 tattaaaaag agtaaaaagc caaaggttga aaattatgaa taactttaca gttaattttg
    19201 tgattcctgt tagacattac aagtcagtac aggattggca gagtgttaaa agcaatcttg
    19261 agtatacgtt gaagtcgatc tttggacaaa caaatgataa ctggcattgt tatattatct
    19321 gcaaccgcgg tacagatttg ccaaaatcaa ccaatcatga aaatgtaact gttttagagt
    19381 ccgattttaa atttatatcc ttaccaaata aaagtgttga tcctgaagcc tatcatgatt
    19441 tgatccgtaa agacaaaggg gcgcgagttt acgaagcctt aaaatattgt aagaccaatg
    19501 atttttttat ggttgtagat tatgatgatt ttgtacatcg taaaatagtt gaattcatca
    19561 atgctatggt caaaaaaaac actgaagcat acttttatgg ttggcttatt aatgtagggt
    19621 atatatattc cggaggtaat gtagctcttt tgaataaatc ttttgataca atatgtggta
    19681 catcaaatat tgttcgcgtt tgtttttttg aaaaattcta tgatgagtat gggaatttgc
    19741 cacttttata cattaaagaa ttactaggaa gccatcgata cataaaaaat tatatgagca
    19801 aggctggtta ttcttatggc agtttgcctt tcccaggggc tgtatataat gtggggattt
    19861 ctaattcatc aagtcaaact gggtcagtag tgaaagaaat cttttcattt ggaaagtttt
    19921 ttaaaatgcc acgtacaatg ataaaattat ggctttctat taggttgttt acaaagaaaa
    19981 agaagaggat gttcaatata aattgttaat tttagataag atatattttt tttgattcaa
    20041 tattaattga acattacctt tcttctcaag aattatactt gtttgtcctt acattattga
    20101 gctaacatta tcatcacatt taagctgcga acatgtcgca gtgaccacac ctgacaggag
    20161 tatgtaatgt ccaagcaaca aatcggtgtt gtcggtatgg ctgtgatggg gcgtaacctt
    20221 gcgctgaaca tcgaaagcca cggttatacc gtatccgttt tcaaccgctc ccgtgaaaag
    20281 accgaagaag tgattgccga taatccaggc aaaaaactgg ttccttatta cactgtacaa
    20341 gagtttgttg aatccctcga aacaccacgt cgtatcctgt tgatggtgaa ggccggggct
    20401 ggcaccgaca gcgccatcga ttccctgaag ccttacctcg ataaaggcga catcatcatt
    20461 gatggcggca acaccttctt ccaggacacc atccgtcgta accgtgaact gtctgccgaa
    20521 ggttttaact ttatcggtac cggtgtttcc ggtggtgaag agggggcttt gaaaggacct
    20581 tccatcatgc ctggtgggca gaaagaagcc tatgagctgg ttgctccgat tctgaagcag
    20641 atcgcggcgg ttgctgaaga cggtgagccc tgtgtgactt atatcggtgc tgacggtgcg
    20701 ggccattatg tgaagatggt tcataacggc atcgagtatg gagacatgca gctgattgct
    20761 gaagcttatg cgctgttgaa aggcggtctg gcactttcca acgaagagct ggcgcaaacc
    20821 ttcaccgaat ggaacgaagg tgaactcagc agctacctga tcgatattac caaagatatc
    20881 ttcaccaaga aggatgaaga gggtaaatac ctcgtcgatg tcattcttga tgaagcagca
    20941 aacaaaggta ccggtaagtg gaccagccag agctcactgg atctcggcga acctctgtct
    21001 ctgatcaccg agtccgtatt tgctcgttac atctcttcgc ttaaagacca gcgtgtagct
    21061 gcttcgaaag tgctgagtgg tccgcaggct caaccggccg gcgataaagc ggaattcatc
    21121 gaaaaagttc gtcgcgcgtt gtacctcggt aaaattgttt cctatgctca gggcttctcc
    21181 cagctgcgag ctgcttctga cgagtacaac tgggatctga actacggcga gatcgctaag
    21241 attttccgcg ctggctgcat cattcgtgcg cagttcctgc aaaagatcac cgatgcttat
    21301 gcgcaaaacg ctggcattgc taacctcctg ctggcaccgt acttcaaaca gatcgctgat
    21361 gactatcagc aggcgctgcg tgatgtcgtg gcgtatgccg tacagaatgg tattccggta
    21421 ccgacgttct ctgccgcaat agcttactac gatagttatc gttccgcagt tctgcccgct
    21481 aacctgattc aggctcagcg tgattacttt ggcgcgcata cttacaagcg taccgataag
    21541 gaaggtgtat tccataccga gtggctggaa taatttttcc tgcagtcagg ccatttggcc
    21601 tgactgttta aatattcatg cctaattttt gaaaattaac taaattactt ccttcagcaa
    21661 ataattaaaa tattttattc tcaagcattt taagaatttg ccatatttat tatcttgtac
    21721 tcttatatta gtctgcttct ggcctcagta aattactggg tgtttaataa cagggtttta
    21781 attaaaggaa attaatatgt tacttcctgt gataatggct ggtggtaccg gcagtcgtct
    21841 ctggccgatg tctcgcgagc tttacccgaa acagttcctc cgtctgttcg ggcagaactc
    21901 catgctgcag gaaaccatca cccgactctc gggccttgaa atccatgaac cgatggtcat
    21961 ctgtaacgaa gagcaccgct tcctggtggc cgaacagctg cgccagctca acaagctgtc
    22021 gaacaacatt attcttgagc cggtcgggcg caacaccgcc ccggccatcg ccctggcggc
    22081 ccttcaggcc acccgtcacg gcgatgaccc gctgatgctg gtcctcgccg ccgaccatat
    22141 catcaataac cagccggtct tccacgacgc catccgcgtc gccgagcagt atgccgatga
    22201 aggtcatctg gtcaccttcg gtatcgtgcc gaacgccccg gaaaccggct atggctacat
    22261 ccagcgcggc gtggccctca ccgacagcgc ccatactccg taccaggtgg cccgcttcgt
    22321 ggagaagccg gaccgcgagc gcgccgaggc ctacctcgcc tccggggagt actactggaa
    22381 cagcggcatg tttatgttcc gcgccaaaaa atacctctcc gagctggcca aattccgccc
    22441 ggatatcctc gaagcctgcc aggccgcggt caatgccgcc gacaacggca gcgacttcat
    22501 cagcattccg catgacattt tctgcgagtg cccggacgag tccgtggact acgcggtgat
    22561 ggagaaaacc gccgacgcgg tggtggtcgg tctcgatgcc gactggagcg acgtcggctc
    22621 ctggtccgcc ctgtgggagg tcagcccgaa agacgtgcag ggtaacgtcc tcagcggcga
    22681 cgcgtgggtg cacaacagcg aaaactgcta catcaacagc gacgagaagc tggtagcggc
    22741 catcggcgtg gagaacctgg tgattgtcag caccaaggac gccgtgctgg tgatgaaccg
    22801 cgagcgttcc caggacgtga agaaggcggt cgagttcctc aagcagaacc agcgcagcga
    22861 gtacaagcgc caccgcgaga tttaccgtcc ctggggccgc tgcgacgtgg tggtccagac
    22921 cccgcgcttc aacgtcaacc gcatcaccgt gaaaccgggc ggcgccttct cgatgcagat
    22981 gcaccaccac cgcgccgagc actgggtcat tctcgccggc accggccagg tgacggtcaa
    23041 cggcaagcag ttcctgctga ctgagaacca gtccaccttt attccgattg gcgccgagca
    23101 cagcctggaa aacccgggcc gcattccgct ggaagtgctg gagatccagt cggggtcgta
    23161 cctcggcgag gacgacatta ttcgtattaa agaccagtat ggtcgttgct aattttttcg
    23221 ggacaaaacg cagaatgaca cagttaacat gctttaaggc ttatgacatc cgtggtgaac
    23281 tgggcgagga gctgaacgag gacatcgcct accgtatcgg ccgcgcctac ggcgaatttc
    23341 tgaaacccgg gaagatagtg gtggggggcg atgtgcgtct caccagcgag tcgctgaagc
    23401 tggcgctggc ccgcgggctg atggacgccg gcaccgacgt gctggatatt ggcctgagcg
    23461 gcacggaaga gatttacttc gccaccttcc acctcggggt ggacggcggc atcgaggtga
    23521 cggcgagcca caacccgatg aactacaacg gcatgaagct ggtgcgcgag aacgcgaagc
    23581 ccatcagcgg cgacaccggc ctgcgggata tccagcgcct ggcggaggag aaccagttcc
    23641 cgccggtgga cccggcgcgt cgcgggaccc tgcgccagat ttcggtgctg aaggagtacg
    23701 tcgaccacct gatgggctac gtggacctgg cgaacttcac ccgtccgctg aagctggtgg
    23761 tgaactccgg caacggggcg gcggggcacg tgattgatga agtggagaaa cgcttcgcgg
    23821 cggccggggc accggtgacc tttatcaagg tgcatcacca gccggacggc catttcccga
    23881 acggtatccc gaacccgctg ctgccggagt gccgccagga caccgccgac gcggtgcgtg
    23941 cgcatcaggc ggacatgggg atcgcctttg acggcgactt cgaccgctgc ttcctgttcg
    24001 atgacgaggc gtcgtttatc gaggggtact acattgtcgg cctgctggcg gaggcgttcc
    24061 tgcagaagca gccgggggcg aaaatcattc acgacccgcg tctgacgtgg aacacggtgg
    24121 acatcgtgac ccgcagcggc ggccagccgg tgatgtcgaa gacggggcat gcgttcatca
    24181 aggagcggat gcgccaggaa gacgccatct acggcgggga gatgagtgcg caccattact
    24241 tccgcgactt cgcctactgc gacagcggga tgatcccgtg gctgctggtg gcggagctgc
    24301 tgtgcctgaa gaacagttcg ctgaaatcgc tggtggcgga ccgccaggcg gcgttcccgg
    24361 cgtcggggga gatcaaccgc aagctgggaa atgcggcgga ggcgatagcg cgcatccggg
    24421 cgcagtatga gccggcggcc gcacacatcg acacaacgga cggtatcagt attgaatacc
    24481 ctgagtggcg ctttaacctg cgcacgtcca acacggagcc ggtggtgcgt ctgaacgttg
    24541 agtccagagc ggatactgcg ttaatgaatg caaaaaccga agagatttta gccctcctca
    24601 agtaatgcat taaccataac ggaagccata gggtcagatt ttaatcgtat ttttgacctt
    24661 atggcttatt cttgacatcc cacaggtcaa agcgtaaaac cgcccacagc attattaaaa
    24721 ttcgtggcta tccgccatta cccagttaac tgattaaagt gtaatcgaat gaaaattact
    24781 atttccggta caggttatgt tggtttatcg aacggtatcc tgattgcgca aaaccacgaa
    24841 gtggtggccc tggatatcgt acaggccaaa gtggatatgc ttaaccagaa gatctctccg
    24901 attgtcgata aagagattca ggaatatctg gcagaaaaac cgttaaattt ccgtgccacc
    24961 acggacaagc acgacgccta tcgtaatgcc gactacgtga tcattgcgac gccgaccgat
    25021 tacgatccca aaaccaacta cttcaacacc tctacagtgg aagcggttat tcgcgatgtc
    25081 acagagatca accc
//
