LOCUS       AB924585               23620 bp    DNA     linear   BCT 28-OCT-2015
DEFINITION  Klebsiella sp. 1196 DNA, capsular polysaccharide synthesis gene
            cluster, serotype: K48.
ACCESSION   AB924585
VERSION     AB924585.1
KEYWORDS    .
SOURCE      Klebsiella sp. 1196
  ORGANISM  Klebsiella sp. 1196
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella.
REFERENCE   1
  AUTHORS   Pan,Y.J., Lin,T.L., Chen,C.T., Chen,Y.Y., Hsieh,P.F., Hsu,C.R.,
            Wu,M.C. and Wang,J.T.
  TITLE     Genetic analysis of capsular polysaccharide synthesis gene clusters
            in 79 capsular types of Klebsiella spp
  JOURNAL   Sci Rep 5, 15573 (2015)
   PUBMED   26493302
  REMARK    DOI:10.1038/srep15573
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23620)
  AUTHORS   Pan,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2014) Contact:Yi-Jiun Pan National Taiwan
            University College of Medicine, Department of Microbiology; 1, Sec
            1, Jen-Ai Rd., Taipei 100, Taiwan
FEATURES             Location/Qualifiers
     source          1..23620
                     /organism="Klebsiella sp. 1196"
                     /mol_type="genomic DNA"
                     /strain="1196"
                     /serotype="K48"
                     /db_xref="taxon:1497822"
     gene            204..1106
                     /gene="galF"
     CDS             204..1106
                     /gene="galF"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose pyrophosphorylase"
                     /protein_id="BAT23888.1"
                     /translation="MKMNMANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVT
                     IMNVRQAQPLGLGHSILCARPVVGDNPFVVVLPDIILDGGTADPLRYNLAAMVARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGR
                     YVLSADIWTELERTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQA
                     FVTYGMRNLKEGAKFRESIKKLLA"
     gene            1500..2129
                     /gene="cpsACP"
     CDS             1500..2129
                     /gene="cpsACP"
                     /note="orf2"
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase homologue"
                     /protein_id="BAT23889.1"
                     /translation="MNWQLISFFGDSTVLLPSAAALFIVLMLRKTSRLLAWQWSLLFG
                     ITGAIVCASKLAFMGWGLGIRELDYTGFSGHSALSAAFWPIFLWLLSARFSAGLQKAA
                     VATGYILAAVVGYSRLVINAHSVSEVIAGLLLGASGSALFLMLQKRTTHSESVRISWG
                     GVACLVMVPLILLHSGNKAPTQSLLGQIATAVGPLDKPFTRTELHKQAW"
     gene            3006..4520
                     /gene="wzi"
     CDS             3006..4520
                     /gene="wzi"
                     /codon_start=1
                     /transl_table=11
                     /product="surface assembly of capsule"
                     /protein_id="BAT23890.1"
                     /translation="MPRALSILVFPSFSLRYDSGAENGSCTMIKIARIAVTLGLLSSL
                     GAQAYAAGLVVNDNDLRNDLAWLSDRGVIHLSLSTWPLSQEEIARALKKAKPSYSSEQ
                     VVLARINQRLSALKADFRVTGYTSTDQPGTPQGFGQTQPADNSLGLAFNNSGEWWDVH
                     LQGNVEGGERISNGSRFNANGAYGAVKFWNQWLSFGQVPQWWGPGYEGSLIRGDAMRP
                     MTGFLMQRAEQAAPETWWLRWVGPWQYQISASQMNQYTAVPHTKIIGGRFTFTPFQSL
                     ELGASRIMQWGGEGRPQSFSSFWDGFTGKDNTGTDNEPGNQLAGFDFKFKLEPTLGWP
                     VSFYGQMIGEDESGYLPSANMFLGGIEGHHGWGKDAVNWYLEAHDTRTNMSRTGYSYN
                     HHIYKDGYYQQGYPLGDAMGGDGQLLAGKVELVTESGQRWSSRLVYSKVNPDNQSFNK
                     VFPHSDTLKGIQLGWSGDVYQSVRLNTSLWYTNANNSDSDDVGASAGIEIPFSL"
     gene            4666..5799
                     /gene="wza"
     CDS             4666..5799
                     /gene="wza"
                     /codon_start=1
                     /transl_table=11
                     /product="putative capsule polysaccharide export protein"
                     /protein_id="BAT23891.1"
                     /translation="MKKKIVRFSALALAIGFLSGCTIIPGQGLNSLRKNVVELPDSDY
                     DLDKLVNVYPMTPGLIDQLRPETVLARPNSHLEDLIRNYEYRIGVGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNSDGTIFYPYIGKVQVAGKTLSQVRQDIASRLTTYIESPQ
                     VDVSIAAFRSQKTYVTGEVIKSGQQPITNIPLTVMDAINAAGGLAPDADWRNVVLTHN
                     GKDTKVSLYALMQKGDLTQNHLLYPGDILFVPRNDDLKVFVMGEVGKQSTLKMDRSGM
                     TLAEAIGNAEGMSQAFSDATGVFVIRQLKQSKDGKIANIYQLNAQDASAMVLGTEFQL
                     QPYDIVYVTSAPIVRWNRVISQLVPTITGVHDLTETGKFIRTW"
     gene            5796..6239
                     /gene="wzb"
     CDS             5796..6239
                     /gene="wzb"
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="BAT23892.1"
                     /translation="MKLMFDSILIVCTGNICRSPIGERYLRALLPEKKIDSAGTGALI
                     DHEADPMAVKIAEKHGLSLSGHNGKQFTSQLARNYDLILVMEKNHIEQIGRLAPEARG
                     KTMLFGHWIKQRDIPDPYRKSEEAFASVFQLIEQAGKCWAEKLGV"
     gene            6255..8414
                     /gene="wzc"
     CDS             6255..8414
                     /gene="wzc"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="BAT23893.1"
                     /translation="MSSIKNKPEVKDSEDFDIGRLLGEIIDHRKLIISITSLFAFTGL
                     LYVLLSTPVYQADALIQVEQKQANAILGNLSQILPDSQPQSAPEIALLQSRMILGKTV
                     DDLNLQIRVEQEHFPIFGKGLSRLLGQKDGTLNISLFSPVDQTEDIQKFKLTVEGNGS
                     YVIYGENVELKGRVGETLDKNGFTVKLSSIQAEPGTSFTVTYVSKLKAISDIQESLTI
                     NDQGKDTGILAISLNGKNPILIKDIINSISQNYLAQNIARQAAQDAKSLDFLNQQLPK
                     VRSDLDEAENKLNDYRRKNDSVDLSLEAKAVLDQIVNVDNQLNELTFRESEISQLYTK
                     EHPTYKALLEKRKTLQEEKGKLNKRVSAMPETQQEILRLSRDVESGRAVYMQLLNRQQ
                     ELNISKSSAIGNVRIIDNAVTQPKPVKPKKVITLLASIILGLFVAVGVVLLRVFLRRG
                     IETPEQLEELGINVYASIPVSETFSLKKMVKKSKKNSYSDAEIFLALENPADLAIEAI
                     RGLRTSLHFAMMEARNNILMISGASPNAGKTFVSTNLAAVISQTGKKVLLIDTDMRKG
                     YTHKLFNVNNDHGLSDFLSGKNDINKTIKTIDVAGFDFIPRGIVPPNPAELLMHKRFG
                     ELLKWANENYDLVILDTPPILAVTDAAIIGNYSGTTLLVARFELNSPKEIEVSIKRFE
                     QSGVHIKGCILNGMVKKASSYYSYGYSHYGYSYTDKK"
     gene            8464..9372
                     /gene="wcaA"
     CDS             8464..9372
                     /gene="wcaA"
                     /note="HG17; orf7"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23894.1"
                     /translation="MKAYIAIPTYNGGSIWEESAKNINLYIPKDTLVHVIDSSSKDNT
                     VDIALNYGFQVLKIDPANFNHGGTRNLAVELHKDEFDIVIFLTQDAIPESNFFENIIT
                     AFHDPSVACAFGRQLPHKNATAIAKHARYFNYSNNKYISSKDKISQMGIKTVFSSNSF
                     SAYRISTFMQLGGFPDNTILSEDMYFAAKAIMEGHKLAYCPDARVRHSHNYNSIEEFK
                     RYFDIGVFHTDESWIRENFGGAGGEGLRFIKSEFNYLIKNKPTEILSAGVHNFAKIVG
                     YKLGQNYKKIPKKYLKNLSMHKRYWS"
     gene            9422..10837
                     /gene="wcaJ"
     CDS             9422..10837
                     /gene="wcaJ"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23895.1"
                     /translation="MKFMTRLSHHVRAKTNASLISMVQRFSDIIIILFGLYLVFYLNG
                     KDYGYNQILASMIVLVLFQMTGGITDFYRSWRGVKFSSEFILVLKNWTVSILLSLGVL
                     SYLNGLWLPFRIFIEWFILVCFCLLFSRMSIRAGARIIRHLGYNTRNVAIAGSMPVGL
                     NLAKSFIEEPWLGFKVVGVYDTKTLVKEAEEYGIEYKGDFHALVQDARAGNLDRIYIA
                     MSMSEEAKMRGLIKSLTDTTCSVILIPDIFTFNILQSRTEEVNGVPVVPLFDTPLNGI
                     NMVFKRLEDIILSLFILLLISPLLIIISLAVKITSPGPVIFRQTRYGMDGKPIKVWKF
                     RSMVVMENDTEVKQATKDDVRVTNVGKFLRRTSLDELPQFFNVLFGEMSIVGPRPHAV
                     SHNEQYRSLIEGYMLRHKVKPGITGWAQINGWRGETDTLDKMEKRIEFDLEYIRSWSV
                     WLDLKIIVMTIFKGFVNKSAY"
     gene            10931..11746
                     /gene="wclL"
     CDS             10931..11746
                     /gene="wclL"
                     /note="HG106; orf9"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23896.1"
                     /translation="MHTQKEDYIKNNIVVYTALFGDYDELIEIPEGMHKCDFICFTDQ
                     QIENNKGWKVIKIENSSDSNVLQNRKYKILPHVFLSEYEYSVYIDSNIRLLRSPESLV
                     IKYLQDVDIALPKHFERDCIYTECEMCISSGKAIQKEVDLLVNEIKNAGFPEKYGLAE
                     NNIIMRRHNSESIVKLMELWWDIFSKSGYPKRDQLSLMYLFWLLNIEYKYMDESSRNN
                     NSFFRFKMHKNANNMPFIKKIAFYISSTRDQNMLHRLGFEIISILSNIKKKIN"
     gene            11760..12725
                     /gene="wzy"
     CDS             11760..12725
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAT23897.1"
                     /translation="MRKLPWYLSIYLLIMLTIVLSCVVGFKNFYIWRDVDTYWAYYDF
                     AYFYNVSYIFSNVQDPIFTILIKPFVHSGRSEGFHLFLIVIAFVTIALKLISMYKRCQ
                     SFYIFLLLYCSYLLFLHDYVQIRVALALGVFVLALYCADSKIIKALLFVVACLIHLSC
                     ILLVLFYYAFKVLGPKKIIKLLPFALIIPSIVFSGVIPVERITTYINMLGNEKKFDQI
                     NLLSTLPILQIIGLLVIYFSKSIKDLSNKFEFSISALGVILFYSLHMIPVFAFRFFEM
                     TNLFFIILLSDGFKKSIYLKLVFVVYILIGLKNSFYGESSLFNLI"
     gene            12737..13540
                     /gene="wcqD"
     CDS             12737..13540
                     /gene="wcqD"
                     /note="HG197; orf11"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23898.1"
                     /translation="MNTLKLSICVVTYESLDMVKKFHTELIRSLDGYSEWEILYFDNS
                     KSDEVIDYITSVKTDNVLIDFDKRNMGFSYGNNRLIINCKYDNVLLLNPDVFDITNNF
                     WGELKLNYNKQDVLFIKLLNEDGTFQDCIGKYASFSRAFGAKVNYEAINQATPIEMGI
                     MAFMLTSKKVLAHVGLLDCDYPLYAEDMDWCYRAKRLGYSIIYNPSLVLTHTGGGSSR
                     TRWRNNKTQLKKYYAEEIFIKKHYKGLHKMAMLALNFVKRINNKMRSFK"
     gene            13537..14586
                     /gene="wckU"
     CDS             13537..14586
                     /gene="wckU"
                     /note="HG86; orf12"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT23899.1"
                     /translation="MSHNVIFPMLSISNHGGVRILLQIANSIANKGGRTKIICPKGTY
                     DTRYNISDKVEIIEVGPAISNKICRWFFFTILFPFYVKNNDTVFANFFVTFYASLLSR
                     ILFKKIKIVYFIQDIEYEFFGGLIKKIAKKLCEYSYAYKKAEIIAANIYLYERLLVKN
                     DAIKLFNVWIDEKFITTASVETHRQYDLIYFLRQDPRKRIDRFEEMLPYLYENNISIL
                     CVTQSLDLADRYSSQLPVFIPENDQELISLIDKCKIYLLTSSQEGFSLPPLECMARGV
                     IPVVFECGGPEIYIEDGLNGFIVNTIDEASETILKLVKSYDSLIEIKTKAVGTARKIS
                     FSEEVDALADKVLQM"
     CDS             14666..16012
                     /note="HG198; orf13"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAT23900.1"
                     /translation="MLSKNINNDNKQKNVASIRQVSSVAELRNTEPNHISEIIFVLGY
                     YENTPFQGGGYFLYDINNTNLDDCGVNIRTRSGNCWRRTDDFSSGLNAQIFGVLDTGE
                     DITEQLNNATEFSLINNIELVLPRGYLRVDGVWKCNGEGFRCRGQGSNNTFVFGTNVS
                     ANCPIFVIKNKNWDIESDPALCRLHGLKLSDFCFTGKIEGNKEQSSCRDALSLHGIGF
                     DFELSSLNFYNIGCRAIVAEDLWDGDIHNCKFHECGQCLQWKTDDDYYQALVFKRKYD
                     SCNAVRITNCHFEHLKRGAIYIEDYCYSFFLTNNKFEAVNQDQRYKEEYPIYIGNNHR
                     CFTMSGGFITLTQQNKNMHYIRGGGDIIRIANVSFIAPQNKDGAAVLNLSTGRFKVGA
                     IISSHFDIRGDLQVEPLLIKGDADFRGSTIKCFRPLRNLEKSEKVINNASFIYDIN"
     gene            16048..17376
                     /gene="wzx"
     CDS             16048..17376
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAT23901.1"
                     /translation="MKKYVYNATWIFAEKIARVIITFITFAFISRQLGPADTGILSFS
                     QSLVIMLLCVTNLGLDSILISEFSNDKPEHHNGKKNEDFIYSTVMIAKFSISFVCVIV
                     CLLILLVANISFNNKLIFILSLISLVFQSNSTFYAYFQAKSKALLLAKFSFFAIIIST
                     VFKVILLYFHANVYWFSFSFSFDVIVLFYLLLIGMRHQNKYISFSYFRRDVLFDLLKK
                     SYPIILSSLLVVLYTRLDQVMILKMMGSESLGIFSVAVKISESYSFIPVAVVTAFFPL
                     IINNNNNDDDIRTYFDLVFASAFFSALLVILFSWLFLEDIFGPAYAGSFSVLSITVFS
                     TVFAVMGAASTNYLVVINLTYMRLIRAIAGLIVNFILNIILIPRIGIVGAAYASLFSQ
                     FFSGFLANGLNKRTWLCFKLQFLSVVTLGIPGIVSLLNKTMKEKKSESIN"
     gene            17360..17848
                     /gene="wcqE"
     CDS             17360..17848
                     /gene="wcqE"
                     /note="HG199; orf15"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="BAT23902.1"
                     /translation="MSQLIKNYIKKTNYLYAFLVFIHGKVFFNVESLIRYFNDRYFSL
                     TYYNNLSLVRACHITVGIKYLFLKKTLIPHPVGIVIGKNVVLGNRCTIYQNVTIGVRN
                     NDEDKYPVLGDNVIVYANACIIGDVKVGNNVIIGSGSLVNKDIPDNAIVKGSPAVVIR
                     FQ"
     gene            18021..19427
                     /gene="gnd"
     CDS             18021..19427
                     /gene="gnd"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate-6-phosphate dehydrogenase"
                     /protein_id="BAT23903.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA
                     ENPGKKLVPYYTVQEFVESLETPRRILLMVKAGAGTDSAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILKQIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLALSNEELAQT
                     FTEWNEGELSSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAQNAGIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRTDKEGVFHTEWLD"
     gene            19651..20715
                     /gene="rmlB"
     CDS             19651..20715
                     /gene="rmlB"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose-4,6-dehydratase"
                     /protein_id="BAT23904.1"
                     /translation="MKILVTGGAGFIGSAVVRHIIENTLDEVRVMDCLTYAGNLESLA
                     PVAGSERYSFSQTDITDAAAVAVQFSEFRPDIVMHLAAESHVDRSIDGPAAFIQTNVI
                     GTFTLLEAARHYWSGLGEEQKQAFRFHHISTDEVYGDLHGTDDLFTEETPYAPSSPYS
                     ASKAGSDHLVRAWNRTYGLPVVVTNCSNNYGPYHFPEKLIPLTILNALAGKPLPVYGN
                     GEQIRDWLYVEDHARALYKVATEGKSGETYNIGGHNERKNIDVVRTICAILDKVVAQK
                     PGNITHFADLITFVTDRPGHDLRYAIDAAKIQRDLGWVPQETFESGIEKTVHWYLNNQ
                     TWWQRVLDGSYAGERLGLNN"
     gene            20742..21611
                     /gene="rmlA"
     CDS             20742..21611
                     /gene="rmlA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyl-transferase"
                     /protein_id="BAT23905.1"
                     /translation="MKGIVLAGGSGTRLYPITQGVSKQLLPIYDKPMIFYPVSVLMLA
                     GIRDILIISTPDDMPSFQRLLGDGSQFGVNFSYAIQPSPDGLAQAFIIGEKFIGNDAC
                     ALVLGDNIYFGQSFGKKLEAAAAKTSGATVFGYQVLDPERFGVVEFDENFKALSIEEK
                     PLKPKSDWAVTGLYFYDNNVVEMAKDVKPSERGELEITTLNQMYLEQGDLHVELLGRG
                     FAWLDTGTHDSLMDASQFIHTIEKRQGMKVACLEEIGYRNQWLSAEGVAAQAERLKKT
                     EYGAYLKRLLNER"
     gene            21643..22533
                     /gene="rmlD"
     CDS             21643..22533
                     /gene="rmlD"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-L-mannose dehydrogenase/
                     dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAT23906.1"
                     /translation="MKILLIGKNGQVGWELQRSLSTLGDVVAVDYFDKELCGDLTNLE
                     GIAQTVRTVRPDVVVNAAAHTAVDKAESERELSDLLNDKGVAVLAAESAKLGALMVHY
                     STDYVFDGAGSHYRREDEATGPLNVYGETKRAGELALEQGNPRHLIFRTSWVYATRGA
                     NFAKTMLRLAGEKETLSIIDDQHGAPTGAELLADCTATAIRETLRNPALAGTYHLVAS
                     GETSWCDYARYVFEVARAHGAELAIQEVKGIPTTAYPTPAKRPLNSRLSNEKFQQAFG
                     VTLPDWRQGVARVVTEVLGK"
     gene            22548..23102
                     /gene="rmlC"
     CDS             22548..23102
                     /gene="rmlC"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-D-glucose-3,5-epimerase"
                     /protein_id="BAT23907.1"
                     /translation="MNIIKTDIPDVLIFEPRVFGDARGFFFESFSSKVFNEAVGRQVD
                     FVQDNHSQSQKGVLRGLHYQLDPHAQGKLVRCVEGEVFDVAVDIRRSSPTFGKWVGAV
                     LSAENKRQLWIPEGFAHGFMALSDTVQFVYKATNYYAPQSERSIIWNDPEIGIDWPAL
                     SDCALSLSEKDLQAHTLATAEVYK"
BASE COUNT     6777 a   4470 c   5406 g   6967 t
ORIGIN
        1 ccgagccgct gaataacctg atggagaata agattattct cacttcaaac tgttggtaaa
       61 aggaagttgt gtgtattctt ttaggtgaca gtgaatttaa gaatttggcg ggcagatgcc
      121 cgggcagtat ccgtgtatta tcagttccaa tggatttgtg acatgtacaa ttttgcaaaa
      181 ctgcgtgttt tgcaaccaaa caggtgaaga tgaatatggc gaatttgaaa gcggttattc
      241 cggtcgcagg actaggcatg catatgctgc cggccacaaa ggcaattcca aaggagatgc
      301 tgccgatcgt tgataagcca atgattcagt acattgttga cgaaatcgtc gccgccggga
      361 tcaaagagat agtcctggtg acgcactcct cgaagaatgc ggtggaaaac cactttgata
      421 cctcctacga gctggaagcc ctgcttgagc agcgcgtgaa gcgccagctg ctggcggaag
      481 tccaggccat ttgcccgccg ggcgtaacca tcatgaacgt gcgccaggca cagccgctgg
      541 gtctgggcca ctccatcctc tgcgcccgcc cggtagtcgg ggacaacccg tttgtggtgg
      601 tgctgccgga tatcattctc gatggcggca ctgcggaccc gctgcgctat aacctcgccg
      661 ccatggtcgc ccgctttaac gagaccggcc gcagccaggt gctggcgaaa cgcatgccgg
      721 gtgatctctc cgaatactcc gttatccaga ccaaagagcc aatggtggcc gaagggcagg
      781 tggcgcgtat cgttgagttc attgaaaaac cggacgaacc gcagaccctg gactccgacc
      841 tgatggcagt gggccgctac gtgctgtcgg cagatatctg gactgaactt gaacgtaccg
      901 agccgggcgc ctggggccgt atccagctaa ctgacgccat tgccgaactg gcgaagaagc
      961 agtccgttga cgcgatgctg atgaccggcg aaagctatga ctgcggtaag aaaatgggct
     1021 acatgcaggc cttcgtcacc tacggaatgc gtaacctgaa agaaggcgcc aaattccgcg
     1081 aaagcattaa aaaactgctg gcctgacagc tggtgtgaag atgagcggta gggcaggggt
     1141 attttgccac gccgctcata acgttatgca gaaattattc ataacgtgaa tgttataacg
     1201 attgtaaaga aacgtatggc ttcggagact tctggtagtt tgtctctggc ctctgtggtg
     1261 caatggtcgg agtagcggca ataatgcttt gtgaatagtc acttagtgcg acaattccta
     1321 aagcgcaggg aaagcggtca acgtcagcca aaaataaaac ttgactgcga tcatgtttcc
     1381 gctttaaaca tctcacttgc atgcataaaa atgtgaaatg aattggcatg cgagctggta
     1441 cagacattac ggataatccc tgagcacggc agtggacatc atcgaaggat cacaggtata
     1501 tgaactggca actcatctca ttttttggcg atagcaccgt tttgctgccc agcgcagcgg
     1561 cgctgtttat tgtcctgatg ctgcgtaaaa cgtcgcggtt gctggcgtgg cagtggagtt
     1621 tgctgttcgg catcaccggc gccatcgtct gcgcctcaaa actggccttt atgggctggg
     1681 gtctgggtat tcgcgagctg gattacaccg gcttcagcgg ccactcagcg ctttccgcgg
     1741 ccttctggcc tatcttcctg tggctgctta gtgctcgttt ttccgcgggc ttgcaaaaag
     1801 cagccgtcgc caccggctat attctggccg ccgtggtggg atattcacgg ctggttatta
     1861 atgcacattc cgtgtcagaa gtaatcgcag gcctgttgct cggcgcttct ggcagcgctt
     1921 tgttcctgat gctgcaaaaa cgtaccaccc attcggaaag tgtgcgtatt tcctggggcg
     1981 gcgtcgcgtg cctggtgatg gtcccgctta tcctgttgca tagcggcaat aaagcgccga
     2041 ctcaatccct gctagggcaa atcgccaccg cagtagggcc gttggataaa ccctttacgc
     2101 gtaccgagct gcataagcag gcctggtaat cgccatttgt tttacagggg aaattaagtt
     2161 ttcgccggtt aattagacaa ataagaaaat aatctactat atgccagtca attgataatt
     2221 catatttatg aaataatgca gtgctactac attgttattg tcaatttgcg tggatatagc
     2281 cgtggtcaga cgtttcttaa atgtgttcag aaagcacctg ttccacgttg gatgaataat
     2341 ctgcatcgag aaactattag aaattgtagt tgactgtcgc gtcatcatct gattttggaa
     2401 tgacgtatgt gtaatggaaa agatgttttt ttacaaagag ttatctttgc ctatgccggc
     2461 atggtggcgc caggcagatg ttaggtagtt aagagcaata aataatcttt attggcgaac
     2521 tgcttatttt tcgccaataa aacagcggat gggattaatt ggcagatatt cggcagtaag
     2581 actcccaatt gtgaccgaaa tcccgtagac ttaacgccgc aaaaaataaa ggcctgacca
     2641 atttatcacc cacaggccga ttaaatacgc cgttcatgta gtcagtgcgc tggtagctgt
     2701 taagccaggg gcggtagcgt cgctgaaacc acctgttgct gcacaaatat cttctctgaa
     2761 cggctataaa aatcgatgca ctttgggtga ttgacgccat aagatatcta tcaagctcat
     2821 cagatatcct cataaatggg tcaggagcag ctgctgatat cgcctgtaca ccaactttcc
     2881 cgtctcatcg atagcctgta cggtaaaatt cgcctacatt gtgagctggg tggatgtgct
     2941 aaggattacg agcagcttag ggtaactgta cttgcctcgc cggtgttgca cagtgatgtc
     3001 tgctggtgcc gcgagcgctt tctatcttgg tattcccctc attctcattg agatacgaca
     3061 gcggggctga aaatggatct tgtacaatga taaaaattgc gcgcattgcc gtgacgctgg
     3121 gcttgctttc ctcactggga gcccaggctt acgcggccgg gttagtagta aatgataacg
     3181 atctacgtaa cgaccttgcc tggctttccg atcgcggggt catccatctg agcctgtcga
     3241 cctggccgct gagccaggaa gagatcgccc gggcgctaaa aaaggccaaa ccgtcctatt
     3301 cttctgagca agtagttctg gcccgtatca accagcggct gtctgcttta aaagccgatt
     3361 tccgggtcac cggctatacc tcgaccgacc agccgggcac cccgcagggg ttcggtcaga
     3421 cgcagccggc agataactcc ttaggcctgg cgtttaataa cagcggcgag tggtgggatg
     3481 tccatctgca gggcaatgtc gaagggggag agcggatcag caacggatcg cgtttcaacg
     3541 ccaacggtgc ctacggtgcg gtgaaattct ggaaccagtg gctctctttt ggccaggtac
     3601 cacagtggtg gggaccgggc tatgaaggaa gcctgatccg cggggatgcg atgcggccga
     3661 tgaccggctt cctgatgcag cgggcagagc aggcggcacc tgaaacctgg tggttgcgct
     3721 gggtaggccc atggcagtac cagatctccg ccagccagat gaatcaatat accgctgtgc
     3781 cgcacacaaa aattatcggt ggtcgtttca ctttcacacc gttccagtct ttagaattag
     3841 gcgcgtcgcg cattatgcag tggggcgggg aagggcgccc gcaatccttc agcagcttct
     3901 gggatggctt taccgggaaa gacaataccg gaacggataa cgagccgggg aaccagttgg
     3961 ccggatttga ctttaagttc aaacttgagc cgaccttggg ctggccggtg agcttctacg
     4021 gacagatgat cggcgaggat gagtctggtt atcttccatc ggcaaacatg ttcctcggcg
     4081 ggattgaagg gcaccatggc tggggcaagg atgcagtgaa ctggtatctg gaagcgcatg
     4141 atactcgtac aaatatgagc cggacaggtt atagttacaa tcatcacatt tataaagatg
     4201 gttattatca gcagggctac ccgcttggag atgccatggg tggtgatggg cagttattag
     4261 ctggaaaagt tgaattagtg acagagagcg gccaaagatg gagttctcgt ttagtgtatt
     4321 caaaagtaaa tccagataac caatcattta ataaagtctt cccgcattcc gatactttga
     4381 aaggcattca gctgggctgg agtggtgatg tttaccagtc tgtacgtttg aatacatcgc
     4441 tgtggtacac caacgctaac aacagcgaca gcgatgacgt tggggccagc gcagggatag
     4501 agataccgtt tagtttataa ggctgaatgc tgaaaacagg ggagggaggg tggtagcgct
     4561 gcaggatgca gtcagctttt ctctctccat aagccggcag ggaagcaacg gctatgacag
     4621 ctgctcagga attggcaaat tttgatttac tgatgatgtg acattatgaa gaaaaaaatt
     4681 gttagatttt cggcattagc gttagcgatt gggtttttat caggttgtac cattatccct
     4741 ggtcagggat taaacagtct gcgtaagaac gtagttgaac taccggacag tgactatgat
     4801 ttggataaat tggtcaatgt ttatccaatg acgcctgggc ttattgatca actccgccct
     4861 gaaactgttc ttgcacgacc taattctcac ttagaggatt taataagaaa ttatgaatat
     4921 cgcattggag taggggatgt tctgatggta acagtttggg atcaccctga actaactact
     4981 ccagcagggc agtaccgtag cgctagtgat acaggcaact gggttaattc cgatggtacg
     5041 attttctatc cttacatcgg taaagtccag gtggcaggta aaacgctaag tcaagttcgt
     5101 caagatattg caagtagatt aacaacttat atcgagagtc cacaggttga tgtcagtatt
     5161 gcggcattta ggtctcaaaa aacatatgta actggtgaag ttataaaatc tggacagcaa
     5221 ccaataacga atatacctct aacggttatg gatgctatta atgctgcagg tggtcttgct
     5281 cctgatgctg actggcgcaa tgtagtttta acgcataatg gtaaagacac aaaagtgtcg
     5341 ttatatgccc ttatgcaaaa gggcgactta actcagaatc atcttttata tccaggagat
     5401 atactttttg ttccacgtaa cgatgatctg aaggtttttg taatgggtga agttggcaag
     5461 caaagcactc ttaagatgga tcgtagcggc atgactcttg ctgaagcaat tggtaacgca
     5521 gaaggcatgt cacaagcctt cagcgatgcc actggtgtat ttgtcatccg gcagctaaaa
     5581 caaagcaaag atggtaaaat tgcgaatatt tatcaactta atgcacagga tgcatcagct
     5641 atggtgttag gcacagagtt tcaacttcag ccttatgaca tagtgtatgt cacctccgct
     5701 ccaattgtac gttggaatcg tgtcatttct caattggttc caacaataac gggcgttcat
     5761 gatttgactg aaacgggtaa atttattaga acctggtgaa attaatgttt gattcgattt
     5821 taatagtatg cacaggaaat atatgtcgct caccgatagg tgagcgatac ctaagagcct
     5881 tattacctga aaaaaaaatt gattcagctg gtactggagc tttgatagac catgaggctg
     5941 atccaatggc cgttaaaatc gcagagaagc atggcctatc tctaagcggg cataatggaa
     6001 aacaatttac atcccaatta gctagaaact atgatttgat tttggttatg gaaaaaaatc
     6061 atattgaaca aattggtaga ttagcgcctg aagccagagg gaaaactatg ttatttggcc
     6121 attggataaa gcaaagagac atcccagatc cgtatcgtaa aagtgaagaa gcatttgctt
     6181 cagtattcca actcatcgag caggcaggta aatgctgggc cgaaaaacta ggtgtttaac
     6241 ttaggaattt tttcatgtca tcaattaaaa ataagccaga agtaaaagat tcagaagatt
     6301 ttgatattgg ccgtttgcta ggggaaatta tagatcatcg gaaattaatt atttccataa
     6361 cttccctttt tgcttttact gggttgctat atgtactctt atcaactcct gtgtatcaag
     6421 cagatgcgct aatacaggtc gagcagaaac aagcaaatgc tattttgggt aatttaagtc
     6481 agattttacc tgatagccag cctcaatcag ccccagaaat agcattgttg cagtcgcgaa
     6541 tgatcttagg aaaaacggtt gatgatctta atctccaaat aagagttgaa caagagcatt
     6601 ttccaatttt cgggaaggga ttgtcacggc ttcttggaca aaaggatggc acattaaata
     6661 tctccttatt ttctccagtt gaccaaacag aagatataca gaagtttaaa ttaacggttg
     6721 agggaaatgg aagttatgtt atatatgggg aaaatgtaga attaaaaggt agggttggtg
     6781 aaaccttaga taaaaatggt tttacagtaa aattaagttc tatccaagca gagcctggca
     6841 cctcatttac tgtaacttat gtatcaaagt taaaggcgat atctgatatt caagagtctt
     6901 taacgattaa tgatcaaggt aaagatactg gaatattagc tatatcttta aatggaaaaa
     6961 accctatact tatcaaggat attattaata gtattagtca aaactattta gctcagaata
     7021 ttgcacgaca agcagcccaa gatgctaaga gtttagattt cctaaaccag cagcttccta
     7081 aagtacgtag tgatttagac gaagcagaaa ataaattaaa cgattatcga agaaaaaatg
     7141 attccgttga tttatcctta gaagctaagg ctgtcttgga tcagatagtg aatgtcgaca
     7201 atcaattaaa tgaattgact ttcagagagt ctgagatatc acaattatat accaaagaac
     7261 atccaactta taaggctctg ttagaaaaga ggaaaacttt acaggaagaa aaaggtaaac
     7321 ttaataaacg agtttcagcg atgcctgaaa cccagcagga aatattacgt cttagtcgag
     7381 atgttgaatc gggacgagcg gtttacatgc agttgcttaa tcggcaacaa gaactcaata
     7441 tttctaagtc tagtgctata gggaacgtta gaattattga taatgctgtt actcagccta
     7501 aaccagtgaa acccaaaaaa gttatcacat tgctggcaag tataattttg ggattatttg
     7561 tcgccgtcgg tgtagttctt ttaagagttt ttttaaggcg cggtattgaa acacctgagc
     7621 aactagagga actaggtata aatgtttatg ccagcattcc tgtatcagaa acattctcgc
     7681 tcaagaaaat ggtgaagaaa tctaagaaaa atagctacag tgatgctgaa atatttctgg
     7741 ctttagaaaa cccagcagac ttagctatcg aggcaattcg tgggcttcgt acaagtctcc
     7801 actttgcgat gatggaagct aggaataata tattgatgat ttcgggtgca agcccaaatg
     7861 caggtaaaac atttgtaagc acaaatttgg cggctgtgat ttctcagacg ggaaaaaaag
     7921 ttttgcttat tgatactgac atgcgtaagg gatatacgca taaactattt aatgtcaata
     7981 acgatcatgg cttatcggat tttctatctg ggaaaaacga tattaacaaa acgataaaaa
     8041 ctatcgatgt tgcaggtttt gattttatac ctaggggaat agtaccaccc aatcctgcag
     8101 aattacttat gcataaacga ttcggtgagt tattgaaatg ggctaatgaa aattatgatc
     8161 ttgtaatatt agatacaccg cctattttag cagtaactga tgctgcaata ataggtaact
     8221 atagcggaac cactttgctt gttgctcgat ttgagcttaa ttcgccaaaa gaaattgaag
     8281 ttagtattaa acgttttgag caaagcgggg tacacatcaa aggctgtatt cttaatggta
     8341 tggtcaaaaa agctagcagt tattatagct atggctatag ccattatggg tactcttata
     8401 ctgataaaaa ataatgaaat gccggaatat ccggcttttc aaaactaaac ggtttaggta
     8461 aaaatgaaag cttatattgc tattccgaca tataatggtg gttcaatctg ggaagaatct
     8521 gcaaaaaata tcaatctata catccctaaa gatactttgg tacacgttat agactcttca
     8581 agtaaagata atactgttga tatagcgctg aattatggct ttcaggtatt aaagattgat
     8641 cctgctaatt tcaatcatgg tggaacacga aatttagctg tagaattaca taaagatgaa
     8701 tttgatatcg ttatcttttt aactcaagat gctattcccg aatcgaattt ttttgagaat
     8761 ataattactg cgttccatga tccaagtgta gcatgtgctt ttgggcgcca attaccgcat
     8821 aaaaatgcaa cagcgattgc caagcatgca cgttatttta attattcgaa taacaagtat
     8881 atctcttcta aagataaaat atctcaaatg gggattaaaa cagtattctc gtccaattca
     8941 tttagtgctt atagaatatc aacatttatg caactaggtg ggtttcctga taatactata
     9001 ttaagcgaag atatgtactt tgctgcgaag gctataatgg aaggtcataa gcttgcgtat
     9061 tgtccagatg ccagagttcg tcattctcac aactataata gtatagaaga attcaaaagg
     9121 tacttcgata ttggtgtgtt tcatactgat gaatcttgga taagagaaaa tttcggtggc
     9181 gcagggggag aaggtcttcg ttttattaag tctgaattta attatcttat taaaaacaaa
     9241 cctactgaaa tattatctgc tggagttcat aacttcgcca aaattgtagg atataaatta
     9301 ggacagaact ataaaaaaat accgaaaaaa tatctaaaaa atttgagtat gcataaacga
     9361 tactggagtt agaaccctct caggggattc tacacagaat accacttaaa ataaatgata
     9421 agtgaaattt atgacaagat tatctcatca cgtgcgagcc aaaacaaatg cgtcattgat
     9481 atcaatggtt caacgttttt cagacataat aataattttg tttgggctat atttagtatt
     9541 ctatttaaat ggtaaagatt atggatataa tcaaatttta gcgagtatga ttgttctagt
     9601 attatttcaa atgacaggag gaataacgga tttttaccgt tcatggcgtg gagtaaaatt
     9661 ctcatcagag tttattttag ttcttaaaaa ttggaccgta agtattttat tatcattagg
     9721 ggttctttca tatcttaatg ggttatggct tccttttcga atttttatag agtggttcat
     9781 tttagtatgt ttttgtttgc ttttttcacg aatgtcaata cgagcagggg cacgtataat
     9841 cagacattta ggatataata caagaaatgt tgctattgct ggttctatgc ctgttggttt
     9901 aaatcttgct aagagcttta tcgaggaacc ttggttggga tttaaggtgg ttggagttta
     9961 tgataccaaa accttagtca aagaagctga agagtacggc attgaatata aaggtgattt
    10021 tcatgcttta gttcaagatg caagagccgg caacttggac cgtatatata ttgcaatgag
    10081 catgagtgaa gaagcgaaaa tgagagggtt aattaaatcg cttactgata caacatgctc
    10141 ggtaatttta attcccgata ttttcacttt taatatattg caatctcgaa cagaagaggt
    10201 aaacggcgta ccggtggttc cattatttga tacccccctt aatggaatta atatggtatt
    10261 taagaggttg gaagatatta tcctatcttt atttatttta ttactaattt cgccattgct
    10321 aattattata tccttagctg taaaaattac atcgcctgga ccagtaattt ttaggcagac
    10381 gcgctatgga atggacggca agcctatcaa ggtatggaag tttcgttcaa tggttgttat
    10441 ggaaaacgat acagaagtta aacaggcaac aaaggatgat gttagagtaa caaatgttgg
    10501 gaaattcttg aggagaactt ctttagatga gttacctcag tttttcaatg tgctgtttgg
    10561 ggagatgtct attgttggtc caagaccaca tgcagtatcg cacaatgagc aataccgaag
    10621 cttaattgag gggtacatgc ttagacataa agttaaacct ggtattactg gttgggctca
    10681 aattaatgga tggcgtggag aaaccgatac actagataag atggaaaaaa ggattgagtt
    10741 tgacttagaa tatatcaggt catggagtgt ttggcttgat ctaaaaatca ttgtcatgac
    10801 aatttttaaa ggctttgtca ataaatctgc atattaattt tatatatcat tactggttgt
    10861 taattcagaa aaacgataaa cattcagtcc attaaaatat taaactcgat cgagctttag
    10921 ggattataga atgcatacgc aaaaagaaga ttatattaaa aacaacattg ttgtttacac
    10981 ggctcttttt ggtgactacg atgaactaat cgaaattcct gagggaatgc ataagtgcga
    11041 ttttatttgc tttactgacc aacaaattga aaataataaa ggttggaaag ttattaagat
    11101 agaaaatagt agtgatagta atgtcttgca gaataggaag tataaaattt tacctcatgt
    11161 ttttttgtct gagtatgaat atagtgtcta tattgattca aatattagat tattgagaag
    11221 ccctgaatct ttagtgataa agtatctaca ggatgttgat attgcacttc caaagcattt
    11281 tgaaagagac tgcatatata ctgaatgtga aatgtgtata tctagtggga aggctatcca
    11341 aaaagaagta gatctattgg ttaatgaaat aaaaaatgct ggttttccag agaaatatgg
    11401 attggctgaa aataatataa ttatgcgccg acataattca gagagtatag ttaaactcat
    11461 ggagttatgg tgggatattt tttctaaaag tggatatcca aaaagagatc agctttcatt
    11521 aatgtatttg ttttggttgt tgaatataga atataaatat atggatgagt catctcgaaa
    11581 taataattcg ttttttagat ttaaaatgca caaaaatgcg aataacatgc cttttataaa
    11641 aaaaatcgca ttttatataa gctcaactag ggatcagaat atgttgcata gattgggttt
    11701 cgaaataata agcatattgt caaatattaa gaaaaaaatc aactgaacta ggattgaaaa
    11761 tgcggaagct accatggtac ctcagtattt acttgcttat aatgttgact atcgttctat
    11821 catgtgttgt aggcttcaaa aatttttata tttggcgaga tgtcgataca tattgggctt
    11881 attatgactt tgcatatttc tacaatgtta gctatatttt ctcaaatgtc caagacccaa
    11941 tatttactat actaattaaa ccttttgttc atagcgggag gagcgaaggg tttcatttat
    12001 ttctaattgt tatagcattt gttactattg ctctgaaatt aatttcaatg tataaaagat
    12061 gccaaagctt ttatattttt ttattgctgt attgctctta tttactattt cttcatgatt
    12121 atgtccaaat acgagttgca ttggctcttg gggtttttgt tcttgctttg tactgcgccg
    12181 atagtaaaat aattaaggca ttattgtttg tagttgcatg cttgatacat ttgtcatgta
    12241 tattgcttgt gctattttat tatgcgttta aagtcttagg tcctaaaaaa attataaaac
    12301 tattgccgtt tgctttaatt ataccgtcta ttgtgttttc aggtgttatt cccgttgagc
    12361 ggataacaac atatataaat atgttaggga atgaaaagaa atttgatcaa ataaacttgc
    12421 tttcaacgtt accaattcta caaataattg ggttgttggt tatttatttt tctaaatcaa
    12481 ttaaagattt atcgaataag tttgagttta gcatatctgc acttggggtt attctttttt
    12541 attctctaca tatgattcct gtttttgcat tcagattttt tgaaatgact aatttgtttt
    12601 ttatcattct cctatctgat ggctttaaaa aatcaatata tctgaaattg gtgtttgttg
    12661 tttatatatt gattggtttg aaaaatagtt tttatggcga atcttcattg tttaatttaa
    12721 tttaacagga tgctttgtga ataccttaaa attatcaatt tgtgtcgtta cctatgaatc
    12781 gttagatatg gttaaaaaat ttcacactga acttataaga agcttagatg gatattcgga
    12841 gtgggagatt ttatactttg acaattctaa atcagacgag gtaattgact atataacatc
    12901 agttaaaact gataatgtgt taattgattt tgataaaaga aatatgggct tttcatatgg
    12961 gaataacaga ttaattatta attgtaaata tgataatgta ttgcttttaa atcctgatgt
    13021 ttttgatata acaaacaact tttggggcga attaaagtta aattacaata aacaagatgt
    13081 gctatttatt aaacttttga atgaagatgg aacattccag gactgtattg ggaaatatgc
    13141 atcattttcc agagcctttg gggcaaaggt taattatgaa gcaattaatc aagccacgcc
    13201 aattgaaatg gggataatgg cttttatgtt aacctcaaaa aaagtgcttg cccatgttgg
    13261 attgctagac tgcgattatc ctctttatgc tgaagatatg gattggtgtt atagagctaa
    13321 aagattaggc tactcaatta tatataatcc atctcttgtc ttaacccata cggggggagg
    13381 ctcttctaga actcgctggc gtaataacaa aacacaactt aagaaatatt atgcagagga
    13441 aattttcata aaaaaacatt ataagggatt acataaaatg gctatgctgg ccctcaattt
    13501 tgtaaaaaga atcaataata aaatgagatc ttttaaatga gtcataatgt tatttttcca
    13561 atgttatcta tttcaaatca tggtggcgta agaattttat tgcaaatagc aaatagcatt
    13621 gcaaataaag gtggtcgtac taaaattata tgtcctaaag gtacatacga tactaggtat
    13681 aatatttctg ataaagttga aataattgaa gtagggcctg cgatatctaa taaaatctgt
    13741 cgttggtttt tttttactat tctctttcca ttttacgtta aaaataatga cacggtattt
    13801 gctaattttt ttgtgacttt ttacgcttcg cttctctcgc ggatattatt taaaaaaatt
    13861 aaaattgtat attttattca agatatagaa tatgagtttt tcggaggttt aattaaaaaa
    13921 atagcaaaaa aattatgcga atattcatat gcatataaaa aagcagagat tatcgctgca
    13981 aacatatatt tatatgagcg gttattagtt aaaaacgacg ctattaaatt atttaatgta
    14041 tggattgatg agaagtttat aacaactgct tcagttgaaa ctcacagaca atacgacttg
    14101 atatattttc taagacaaga cccaaggaaa agaattgata gatttgaaga gatgttacct
    14161 tacctttatg aaaataatat ctctatttta tgtgttactc aatctctcga cttagctgat
    14221 agatactctt cgcaacttcc tgtttttatt cctgaaaatg atcaagaact tatttcatta
    14281 attgataaat gtaagatcta tcttctaact agttcgcaag aggggttttc actaccccca
    14341 ctagaatgta tggcgcgtgg tgtaatcccc gttgtttttg aatgtggtgg acctgaaata
    14401 tatattgaag atggcctgaa tggttttata gtcaatacaa ttgatgaagc gtccgagaca
    14461 attcttaagc tggtaaaaag ttatgattcc ttaattgaaa ttaaaactaa agcggtcggc
    14521 acagctagaa aaatatcttt ttcagaagaa gtagatgcct tagctgacaa ggtgttacaa
    14581 atgtaatagg gggttatatg aaaagacgtt cttttttagg tggcgggttt ttatatccgc
    14641 tgctaagttt tttttttcga gtgaagtgtt atccaaaaat atcaataatg ataataaaca
    14701 aaaaaatgtt gctagtataa gacaagtttc ctccgtggct gagttacgga atacagagcc
    14761 aaaccatata tctgaaataa ttttcgtatt aggatattat gaaaacactc cttttcaagg
    14821 aggtggatat tttttatatg atataaataa taccaattta gatgattgcg gcgttaatat
    14881 ccgtacaaga tctggaaatt gctggcgacg tactgatgat ttttcgtcag gtttgaatgc
    14941 gcagatattc ggtgtgttag atactgggga agacataact gaacagttaa ataatgcaac
    15001 tgagttttct ttaataaaca atatagaatt agttttacct agaggttatc ttagagtaga
    15061 tggtgtctgg aaatgtaatg gtgaagggtt tcgttgtaga ggccaaggat caaataacac
    15121 ttttgttttc ggtactaatg tatcagcgaa ttgtccaatt tttgtaataa aaaataaaaa
    15181 ctgggatatt gaatctgatc ctgccctttg tcgattacat ggattaaaac ttagcgattt
    15241 ctgttttact ggtaaaatag aaggaaataa agagcaatca tcttgccgtg atgcgctttc
    15301 tttgcatgga attggttttg attttgaact atcatcattg aatttttata atattggttg
    15361 tcgagcaatt gttgcagaag atttatggga tggggatatt cataattgca agtttcatga
    15421 atgtggacag tgcttacaat ggaagactga tgatgattat tatcaggctc tagtttttaa
    15481 aagaaaatat gatagttgta atgcagtaag aattacaaat tgccatttcg aacaccttaa
    15541 aagaggtgcg atatacatcg aagattattg ttattctttt tttcttacaa ataataaatt
    15601 tgaagcggtt aatcaagatc agcgctataa agaagaatac cctatatata taggtaataa
    15661 tcatagatgc tttactatgt ctggtggatt tattacgctt acgcaacaaa ataaaaatat
    15721 gcattatata agaggtggag gtgatataat tcgtatcgct aatgtatctt ttattgctcc
    15781 tcaaaacaaa gacggtgctg ctgtacttaa tctttcaact gggcgattta aagttggtgc
    15841 tattatttca tcacactttg acattagagg tgacttacaa gtagaaccat tgctcatcaa
    15901 aggtgatgcc gattttaggg gctcaactat aaaatgcttt cgacccttaa gaaatttaga
    15961 aaaaagcgaa aaagttataa ataatgcatc atttatatat gatataaatt aacatttgat
    16021 tttaaatgat tattcttaag gctttttatg aagaaatatg tttataatgc gacttggatt
    16081 tttgcagaaa aaatagctcg ggttataatt acttttataa cctttgcatt tatttccaga
    16141 cagctcggac ccgctgatac aggaattcta agttttagtc aaagtctagt tattatgtta
    16201 ttgtgcgtaa caaacttagg gctcgatagc attttaatta gtgagttttc aaatgataag
    16261 ccagagcatc ataatggaaa gaaaaatgaa gattttattt attcgactgt aatgattgct
    16321 aaattttcta tttcttttgt ctgtgtgatt gtgtgcttgt tgatattgct tgtagcaaat
    16381 atttcattta ataataagct gatttttata ttgtctctaa tatcacttgt gtttcagtcg
    16441 aacagtactt tctatgccta tttccaggct aaatcaaaag ctcttctttt agctaaattc
    16501 agtttttttg caataattat ttcaacagtt tttaaagtta tacttttgta ttttcacgcc
    16561 aatgtttatt ggttttcttt ttctttttcg tttgatgtta tcgttctttt ttatttgttg
    16621 ttgattggaa tgagacatca aaataaatat atttcatttt cttattttag acgagatgtt
    16681 ttatttgact tattaaaaaa atcttacccc ataatccttt catctttatt agtggtttta
    16741 tatactagac tggaccaagt catgattttg aaaatgatgg gttcagagtc actcggaata
    16801 tttagtgtcg ccgttaagat ttcggagtct tattccttca tacctgtcgc ggtcgttact
    16861 gccttttttc cattgataat aaataataac aacaatgatg atgatatcag aacctatttc
    16921 gaccttgttt tcgctagtgc ttttttttct gcattgcttg tgatactttt ttcatggctt
    16981 tttttagagg atatttttgg accggcttat gcagggagtt tctcagttct ttcaataact
    17041 gtattttcca ctgtatttgc agtaatggga gcagcaagta ctaattattt agtagtcata
    17101 aatctcacct atatgcgatt aattcgagct attgcagggt taattgtaaa tttcatttta
    17161 aatatcatct taattcctcg cattggtatc gttggcgcag cctacgcgtc tttatttagc
    17221 cagttttttt ctggattttt agcaaacggg ctcaataaaa gaacgtggtt atgttttaag
    17281 ctacagtttt tgtcagttgt tacccttggt attcccggga ttgtaagcct acttaataaa
    17341 acgatgaagg agaaaaaaag tgagtcaatt aattaaaaat tatataaaaa agactaatta
    17401 tttgtatgct tttttggttt tcattcatgg gaaggttttt tttaatgttg aatctttgat
    17461 cagatatttc aatgatcgtt atttttcgtt aacttactat aataatttat cacttgttcg
    17521 agcatgccat ataacagtag gtataaagta tcttttttta aaaaaaacat taatccctca
    17581 tcctgttggt attgtaatag gtaaaaatgt agttcttgga aatcgatgta caatatatca
    17641 gaatgttaca attggtgttc ggaataatga tgaagataag tatcctgttt taggtgataa
    17701 tgtgatagtg tacgctaacg catgtattat tggtgatgta aaagtaggaa acaatgttat
    17761 tattggttca ggtagcttgg tcaataaaga tattccagac aatgctattg ttaaaggtag
    17821 tccagctgtt gtgatcagat ttcaatgata ttttttttca cagaatgatt aaatttaaat
    17881 ataaatattt tttttgcctt ttcatcttct ttatctccta attattttca ctataccttt
    17941 tgtttgtttt aaactaaaat gtattttcag aatataagct gtgattatct cgcagtgttt
    18001 acacctgaca ggagtatgta atgtccaagc aacagatcgg ggttgtcggt atggctgtga
    18061 tggggcgtaa tcttgcgctg aacatcgaaa gtcgtggtta taccgtctcc gttttcaacc
    18121 gctcccgtga aaagaccgaa gaagtgattg ccgaaaatcc aggcaagaaa ctggttcctt
    18181 actacacagt acaagagttt gttgaatccc tcgaaacacc acgtcgtatc ctgttgatgg
    18241 tgaaggccgg ggctggcacc gacagcgcca tcgattccct gaagccttac ctcgacaaag
    18301 gcgacatcat cattgatggc ggcaatacct tcttccagga caccatccgt cgtaaccgtg
    18361 aactgtctgc cgaaggtttt aactttatcg gtaccggtgt ttccggtgga gaagaggggg
    18421 ctctgaaagg gccttccatc atgcccggtg gccagaaaga agcctatgag ctggttgctc
    18481 caattctgaa gcagattgct gcggttgctg aagacggcga gccatgtgtc acctatatcg
    18541 gtgctgatgg tgctggtcat tatgtgaaga tggttcataa cggcatcgag tatggcgata
    18601 tgcaactcat tgcagaagct tatgcgctgt tgaaaggcgg tctggctctt tccaacgaag
    18661 agctggcgca aaccttcacc gaatggaacg aaggtgaact gagcagttac ctgatcgaca
    18721 ttaccaaaga tatcttcacc aagaaggatg aagaaggtaa gtacctcgtt gatgtcattc
    18781 ttgatgaagc tgcaaacaaa ggtaccggta agtggaccag ccagagctca ctggatctcg
    18841 gcgaacctct gtctctgatc accgagtccg tatttgctcg ttacatctct tcgcttaaag
    18901 accagcgtgt agctgcttcg aaagtgctga gtggtccgca ggctcaaccg gccggtgata
    18961 aagcggaatt tatcgaaaaa gttcgtcgcg cgttgtacct cggtaaaatc gtctcctatg
    19021 ctcagggctt ctcccagctg cgtgctgctt ctgatgaata caactgggat ctgaactacg
    19081 gcgagatcgc taagattttc cgcgctggct gcatcattcg tgcgcagttc ctgcagaaga
    19141 tcaccgatgc ttatgcgcaa aacgctggca ttgctaacct cctgctggcg ccgtacttca
    19201 aacagatcgc tgatgactat cagcaggcgc tgcgtgatgt cgtggcttat gccgtgcaga
    19261 atggtattcc ggtaccaacg ttctcagccg caattgccta ctatgacagc taccgttccg
    19321 cagttctgcc agctaacctg atccaggctc agcgtgatta ctttggtgcg cacacctata
    19381 agcgcactga taaggaaggc gttttccaca ctgagtggtt agattaatat ttgtcttatt
    19441 agacctcctg gaatttattg gaggtctaat attaaagtat atatagaatc aaattctatt
    19501 ctgacaagtg gcgcaacatt aagaattttg ctatttgttt ttaaaatgtt ccttcgatat
    19561 tatccccaaa aaaatacatc tccaatattt taatgtgtag atgtatgcaa ttattttctt
    19621 tttgcatgag taatcaaagg taaataaaat atgaagattc ttgtcaccgg tggcgcaggc
    19681 tttatcggct ctgctgtggt tcgtcatatc attgaaaata ccctggacga agtccgtgtg
    19741 atggactgcc taacctatgc cggcaacctt gaatccctgg cgccggtggc cgggagcgag
    19801 cgctactcgt tttcccagac tgatatcacc gatgccgctg ccgtggcggt ccagttcagc
    19861 gaattccgcc cggatatcgt gatgcacctg gcggcagaaa gccatgtgga ccgttccatt
    19921 gatggcccgg cggcctttat ccagaccaac gtgatcggca ccttcactct gctggaggcg
    19981 gcccgtcact actggtccgg gcttggggag gagcagaagc aggctttccg cttccaccac
    20041 atctccaccg atgaagtgta cggagacctg cacggcaccg atgatctgtt caccgaagaa
    20101 accccgtacg cgccgagcag cccgtactcc gcctccaaag cgggcagcga ccatttggtt
    20161 cgcgcctgga accgcaccta cggcctgccg gtggtggtga ccaactgctc caacaactat
    20221 ggtccgtatc acttcccgga gaaactaatc ccgctgacta tccttaatgc cctggcgggt
    20281 aaaccgctgc cggtatatgg caacggggag cagatccgtg actggctgta tgttgaggac
    20341 catgcccgtg cgctgtacaa agtggcgacc gaaggcaaga gcggcgagac ctacaatatc
    20401 ggcggtcata acgagcgtaa aaatatcgat gtggtgcgca ccatctgcgc cattctcgac
    20461 aaggtggtgg cgcagaagcc gggcaacatc acccactttg ctgacctgat cacttttgtc
    20521 accgaccgtc cgggacacga cctgcgctac gccattgatg ccgcaaaaat tcagcgcgat
    20581 ctgggctggg tgccgcagga gacgttcgag agcgggattg aaaaaaccgt gcactggtat
    20641 ctgaacaacc agacctggtg gcagcgcgtg ctggacggct cctatgccgg cgagcgtctg
    20701 ggcctcaata actgatatct gactaattaa ggaatagatt tatgaaaggt attgttctgg
    20761 ccggcggctc cggcacgcgt ttatatccga tcacccaggg cgtctccaag caactgctgc
    20821 caatctatga caagccgatg attttctacc cggtgtccgt cctgatgctg gcgggcattc
    20881 gcgatatcct gatcatctct acaccggatg atatgccctc cttccagcgc ctgctgggcg
    20941 atgggtcgca gttcggggtg aacttcagct acgctatcca gccgtcgccg gacggcctgg
    21001 cgcaggcctt tattattggc gagaagttca tcggcaacga tgcctgcgcc ctggtgctgg
    21061 gggataatat ctactttggc cagagcttcg gtaaaaagct ggaagcggca gcggcgaaga
    21121 cctccggtgc cacggtgttt ggttaccagg tgctggatcc ggagcgcttc ggggtggtgg
    21181 agttcgacga gaactttaag gcactgtcca tcgaggagaa accgctgaag ccgaaatccg
    21241 actgggcggt gaccgggctc tacttctatg acaacaacgt ggtggagatg gcgaaggacg
    21301 tgaagccttc tgaacgcggc gagctggaga tcaccaccct gaaccagatg tatctggagc
    21361 aaggtgacct gcatgttgaa ctgctggggc gcggttttgc ctggctggac acgggcaccc
    21421 acgatagcct gatggacgca tcacagttta ttcacaccat tgagaagcgc caggggatga
    21481 aggtcgcctg cctggaagag attggttacc gcaatcagtg gctgtcggcg gaaggggtgg
    21541 cggctcaggc cgaacgcctg aagaaaaccg agtacggtgc ttatctgaag cgcctgctga
    21601 acgagcgtta atgctttctc cgtcaacgac aggatacaga gaatgaagat tttactgatt
    21661 ggcaagaatg gccaggtggg ctgggagctc cagcgttcac tgtccaccct cggcgacgtg
    21721 gtcgcggtgg actactttga taaagagctg tgcggcgatc tgacgaatct ggaaggcatc
    21781 gcgcagaccg tgcgtaccgt ccgcccggac gtggtggtga atgccgccgc gcacacggca
    21841 gtggacaagg ccgaaagcga gcgggagctc tccgacctgc tgaacgacaa aggggtggcg
    21901 gtgctggcgg cagagtcggc gaagctgggt gccctgatgg tgcattattc cacggactat
    21961 gtgttcgacg gcgccggcag ccattatcgc cgggaagatg aagcaaccgg cccgctgaac
    22021 gtctacggtg aaaccaaacg cgccggtgaa ctggcgctgg agcagggcaa cccgcgtcat
    22081 ctgattttcc gtaccagctg ggtgtatgcc acccgcggcg ccaactttgc caaaaccatg
    22141 ctccgcctgg cgggtgagaa agagacgctc tccatcattg acgaccagca cggggcgccc
    22201 accggcgctg agctgctggc agactgcacg gcgacggcaa tccgtgaaac gctgcgtaat
    22261 ccggcgctgg ccggcaccta tcatctggtg gccagcggcg agaccagctg gtgcgactac
    22321 gcccgctatg tgtttgaggt ggcgagggcg cacggtgcag agctggcgat ccaggaagtg
    22381 aagggcattc cgacgacggc ctatccgacg ccggcgaagc gtccgctcaa ctcacgcctg
    22441 tcgaatgaaa aattccagca ggcatttggg gtgactctcc cggactggcg tcagggtgtg
    22501 gctcgcgtgg taacggaagt tctgggcaaa taaacgggta gcaaaagatg aacattatta
    22561 aaacagatat tcctgacgtg ctgatttttg aaccgcgcgt gtttggtgat gcgcgaggtt
    22621 tcttctttga gagcttcagc agcaaggtgt ttaatgaggc ggtgggccgc caggtggatt
    22681 ttgttcagga caaccactcc cagtcccaga aaggcgtatt gcgtgggttg cactatcagc
    22741 tggatccgca cgcccagggc aaactggtcc gctgtgtgga aggtgaggta tttgacgtgg
    22801 cggtggatat ccgtcgttca tcgccaacct ttggcaaatg ggtaggagca gtgctcagcg
    22861 cagagaataa acgtcagctg tggatcccgg aagggttcgc ccacgggttt atggcgctga
    22921 gcgacacggt gcagtttgtc tacaaggcga cgaactacta cgcgccgcag tcagaacgga
    22981 gcatcatctg gaacgatccg gagatcggga ttgactggcc ggcgctgagc gattgcgcgc
    23041 tctcgctgtc ggagaaagat ctgcaggcac atactcttgc cactgcagaa gtatataaat
    23101 aattaggttg ttttttccta aaatggcggg ttccagatgg aactcgtcat gtttcttcgt
    23161 taacaagccg ggtcaaccga ccgacttgac ttaccttcct tctcagcgta aaaccgccaa
    23221 cagcattatt taaattcgtg gctatccgcc attacccagt taactgatta aagtgtaatc
    23281 gaatgaaaat tactatttcc ggtacaggtt atgttggttt atcgaacggt gtcctgattg
    23341 cgcaaaacca cgaagtggtt gctctggata tcgtacaggc caaagtggat atgcttaacc
    23401 agaagatctc tccgattgtg gataaagaga ttcaggaata tctggcagaa aaaccgttaa
    23461 atttccgtgc caccacggac aagcacgacg cctatcgtaa tgccgactac gtgatcattg
    23521 cgacgccgac cgattacgat cccaaaacca actacttcaa cacctctaca gtggaagcgg
    23581 ttattcgcga tgtcacagag atcaaccccc gcgttcgggt
//
