LOCUS       AB371292               23101 bp    DNA     linear   BCT 05-MAR-2010
DEFINITION  Klebsiella pneumoniae capsule polysaccharide synthesis gene
            cluster, complete cds, strain: VGH404.
ACCESSION   AB371292
VERSION     AB371292.1
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella.
REFERENCE   1
  AUTHORS   Shu,H.Y., Fung,C.P., Liu,Y.M., Wu,K.M., Chen,Y.T., Li,L.H.,
            Liu,T.T., Kirby,R. and Tsai,S.F.
  TITLE     Genetic diversity of capsular polysaccharide biosynthesis in
            Klebsiella pneumoniae clinical isolates
  JOURNAL   Microbiology (Reading, Engl.) 155 (PT 12), 4170-4183 (2009)
   PUBMED   19744990
REFERENCE   2  (bases 1 to 23101)
  AUTHORS   Wu,K.M., Shu,H.Y. and Tsai,S.F.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-DEC-2007) Contact:Shih Feng Tsai National Health
            Research Institutes, Division of Molecular and Genomic Medicine;
            35, Keyan Road, Zhunan Town, Miaoli County, Taiwan 350, Republic of
            China
COMMENT     This sequence was determined by the K. pneumoniae Genome Project at
            the Yang-Ming University VYM Genome Research Center. Funding to
            this study were from NRPGM of R.O.C.
FEATURES             Location/Qualifiers
     source          1..23101
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="VGH404"
                     /serotype="K5"
                     /isolation_source="isolated from pus of a patient who has
                     adenocarcinoma of sigmoid colon with tumor penetrating and
                     pelvic abscess"
                     /db_xref="taxon:573"
     gene            1..897
                     /gene="galF"
     CDS             1..897
                     /gene="galF"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAI43754.1"
                     /translation="MNMANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVD
                     EIVAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVTIM
                     NVRQAQPLGLGHSILCARPVVGDNPFVVVLPDIILDGGTADPLRYNLAAMIARFNETG
                     RSQVLAKRMPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGRYV
                     LSADIWAELERTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQAFV
                     TYGLRNLKEGAKFRESIKNLLA"
     CDS             1290..1919
                     /note="orf2"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acid phosphatase"
                     /protein_id="BAI43755.1"
                     /translation="MNWQLISFFGDSTVLLPSAAALFIVLMLRKTSRLLAWQWSLLFG
                     ITGAIVCASKLAFMGWGLGIRELDYTGFSGHSALSAAFWPIFLWLLSARISVGLRKVA
                     VITGYVLAAVVGYSRLVIHAHSVSEVIAGLLLGAAGSALFLVLQKRTSDPESVNISWG
                     GVACLVMVPLILLHSGSKAPTQSLLGQIATAVGPLDKPFTRTDLHKQAW"
     gene            2796..4310
                     /gene="wzi"
     CDS             2796..4310
                     /gene="wzi"
                     /codon_start=1
                     /transl_table=11
                     /product="conserved hypothetical protein"
                     /protein_id="BAI43756.1"
                     /translation="MPRVLSILVFPSFSLRYDSGAENGSCTMIKIARIAVTLGLLSSL
                     GAQAYAAGLVVNDNDLRNDLAWLSDRGVIHLSLSTWPLSQEEIARALKKAKPSYSSEQ
                     VVLARINQRLSALKADFRVTGYTSTDQPGTPQGFGQTQPADNSLGLAFNNSGEWWDIH
                     LQGNVEGGERISNGSRFNANGAYGAVKFWNQWLSFGQVPQWWGPGYEGSLIRGDAARP
                     MTGFLMQRAEQAAPETWWLRWIGPWQYQISASQMNKYTAVPHTKIIGGRLTFSPFQSL
                     ELGASRIMQWGGEGRPQSFSSFWDGFTGQDNTGTDNEPGNQLAGFDFKFKLEPTLGWP
                     ISVYGQMVGEDEAGYLPSANMYLAGVEGHHAWGKNAVNWYVETHDTRDDRSRTDYIYT
                     HHIYKDGYYQQGYPLGDAMGGDGQLVAGKVELVTEDNQRWSTRLVYAKVNPENQLINK
                     AFPHSDTLKGVQLGWSGDVYKSVRLNTNLWYTNADNSDSDDIGASAGIEIPFSL"
     gene            4433..5566
                     /gene="wza"
     CDS             4433..5566
                     /gene="wza"
                     /codon_start=1
                     /transl_table=11
                     /product="integral outer membrane lipoprotein"
                     /protein_id="BAI43757.1"
                     /translation="MKKKIIRVSAVALAMSLLVGCTIVPGQGLNSLRKNTVELPDSDY
                     DLDKLINVYPMTPGLIDQLRPETILARPNPQLDSLLQSYEYRIGIGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNSDGTIFYPYIGKVQVAGKTLSQVRQDIASRLTTYIESPQ
                     VDVSIAAFRSQKAYVTGEVVKSGQQPITNIPLTVMDAINTAGGLAPDADWRNVVLTHN
                     GKDTKISLYALMQKGDLTQNHLLYPGDILFVPRNDDLKVFVMGEVGKQSTLKMDRSGM
                     TVAEALGNAEGMSQTFSDATGVFVIRQLKDDKQGKIANIYQLNAQDASAMVLGTEFQL
                     QPYDIVYVTTAPIVRWNRVISQLVPTITGVHDMTETGKFIRTW"
     gene            5572..6006
                     /gene="wzb"
     CDS             5572..6006
                     /gene="wzb"
                     /codon_start=1
                     /transl_table=11
                     /product="putative protein tyrosine phosphatase"
                     /protein_id="BAI43758.1"
                     /translation="MFDRILIVCTGNICRSPIGERFLRNLLPNKKIDSAGIGALVNHT
                     ADPSAVKIAAQHGISLEGHSGQQFTSSLGRQYDLILVMEKYHLEQIGRIAPEARGKTM
                     LFGHWIDQREIPDPYKKSEEAFLSVYKLIEQAGKYWAKKLSA"
     gene            6023..8191
                     /gene="wzc"
     CDS             6023..8191
                     /gene="wzc"
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane tyrosine autokinase"
                     /protein_id="BAI43759.1"
                     /translation="MSSSANKTNVNDASEIDLSRLVGELIDHRKLIISVTSLFTLIAI
                     IYALFATPIYQADALVQVEQKQANAILSNISQMLPDSQPQSAPEIALLQSRMILGKTV
                     DDLNLQTEIQQNYLPLIGRGIARITGEKSGEVSISHLNMPLSENNDQPIELTLKVLGD
                     NRYLLSGDDFSINGIVGELVDGKAISIKIDKINADVGAEFTISYISKLQAITELQKYL
                     NVTEQGKDTGILNVSLIGDDASLIKKTVDSITNNYLTQNIARQAAQDEKSLEFLDNQL
                     PKVRNELDLAEDKLNAFRKKNDSVDLSLEAKSVLDQIVNVDNQLNELTFRESEISQLY
                     TKEHPTYKALMEKRKTLQDEKAKLNKRVSAMPETQQDILRLSRDVESGRAVYMQLLNR
                     QQELNIAKSSAIGNVRIIDEAVTQPKPVKPNKILVVLIGVILGGVVSVGLVLVRVFLR
                     RGIETPEQLEELGINVYASIPVSEEYAKKADKTRNWSKNKLEQKNALLALDNPADLAI
                     ESIRGLRTSLHFAMMEARNNVLMISGASPNAGKTFVSSNLAAVIAQTGKKVLYIDVDM
                     RKGYTHRLFNVSNDNGLSDILSGKIEISKAIKKIDSIGFDFISRGMVPPNPAELLMHR
                     HFGEVINWASSHYDIVVLDTPPILAVTDAAIIGNYVGTTLLIARFEQNTAKEIEISVK
                     RFEHSGVSVKGCILNGVVKKASNYYSYGYSSYGYSYTDEK"
     CDS             8365..9576
                     /note="kp5A"
                     /codon_start=1
                     /transl_table=11
                     /gene="wzy"
                     /product="polymerase"
                     /protein_id="BAI43760.1"
                     /translation="MFFIIFSMFIVFSIIMLIGSPKKSFFIFLLIIAIIPTGNSYADF
                     ISLQGVYYFDFYLIGFFILILKSIMSYSSEKNISIPYSTLFGIFTYLCIILVSVVSNN
                     IVDKYLLKDIRPVIMIFTAVYFSGLVLRIDGYNKNTIFKILFVMFIFSIIHLILPRLG
                     VSVYKDEYYEDNSYRYLDASTYVAAIYIINYFTSNMKNECGKWARLCFYAAILCVLVG
                     NSRFMLLAIFASIIFVSVKDVKKMAIYSLSAILVAGLFLGVSVYVGADRVVNGFSGDV
                     LLFQITNRFSPALSLIDKMSWYNYIFGLGAGTYFDIPWFAYRGLETQNISVDSLYLTM
                     YVKYGLFGLMLIALFTKVAVNGLKANVKKAVIIFCLIMYFVSAIPYHPYSLGIIVGGA
                     VMILLNRKEVV"
     CDS             9582..11024
                     /note="kp5B"
                     /codon_start=1
                     /transl_table=11
                     /gene="wzx"
                     /product="flippase"
                     /protein_id="BAI43761.1"
                     /translation="MHMQNNSILSRLLKDSTWSMISTFANKISFVIVGIIVARILGAE
                     KFAIFAIIQSVVVMLANVFSQSITTATSKHIAEYIEFDKNKVGAGIVATLIFSMLFAS
                     TICLCANFFPNEFSIYLLFHEDYLIFVSSTAGIIVLTIGLGWVQGVFSGFRNFKLNAA
                     INLLYAGISVPFAYVLTSKYGVSGAFYSVIISQSVTLIISTLFIFFILKKNHVRFIIK
                     SSWRERGVITHVGLPVFLTGIIVAPITWYSNKLLSVLSDGLNQLAVFAASMQWSSIFT
                     QVSVVLGAVLIPMLAANKDKNNELLDRINFYSSWLFTIICTVPLIIFVDLFVRIYGKF
                     NLTSDFKVSVIFVLFSAILTSFKGGVARKIIILNLSWFSVLSNLGWAFIFVALTWKTK
                     KYGAVGITGALFFSQFIHFIITIPYFLKRKIIDISMIFNIHVLTLIFVPMISIYVSFR
                     IDSLILKAIACVVIMVFSVFKSIDLIKIRK"
     CDS             11032..12174
                     /note="kp5C"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAI43762.1"
                     /translation="MKKNKVYIRGAYAPGNIGDDVLMLSVINIVKKVVPEKFISVGVE
                     HPSLARKYNSNIDWIHIKKPISADVVVFGGGGQFFSFNPPPGVKSSLISKVIKSIKAQ
                     ENLFTAIERLMVSSCGGLDKIYIPRKLAAFCIGLGPFDNHGKGYQRAVEIINKCDYVS
                     VRDDKSKSYCKMLGNESVSEFTDPTLLSDIWYPNQIKKPYYSDKGYISIVLRDWPHDK
                     NGQDFTKELIKFGNYLINNGEKVRFVSVYKEREEDLIAKNDNIDWLVWDARNYSIVEF
                     MNEFVGNSEVIISSRAHGVLLPASLGVPTIAVAIENKLLKVHDMISDGNIIVKIAEHK
                     AFDEALTCFRKDKEQLRVNLEQEITKNHQKVKDAIDEFTKWLKDNV"
     CDS             12131..12985
                     /note="kp5D"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAI43763.1"
                     /translation="MQLMNLQNGLRITFDLNVICIALSLIMPRQSLADELDFKKLGLN
                     DTFKQDILNIEGIRNYYVFDEKEGAFRVYYPAGSFDPQSMKSKHLPSGGMNFKWAPFY
                     SRNKECAIIQYSVRFPKSFDFVKGGKLPGLYGGNGNTGGKIPNGYDGFSVRLLWVENG
                     MGKVYAYLPQEDKKQKWGVGLSGLPWFYPRGEWQNITLKVKLNTVNFQNGIVKLWVNN
                     KLVIDRRDVLFRKTPNLKIDGVLFSTFFGGNNPSFAPKELQYLDFKDIKISDWFSKQM
                     RCEHDETD"
     CDS             12969..13517
                     /note="kp5E"
                     /codon_start=1
                     /transl_table=11
                     /product="hexapeptide repeat containing protein"
                     /protein_id="BAI43764.1"
                     /translation="MMKLIKLNAKKVIIGFLNAILSLSTFFVVRRFLLRVLFRAIVGN
                     KSTVHRKVKIFDIGSLSIGKHSTINYGCFLDNRGGLDIGDNVNISHCVKIYTMGHDLD
                     DPFAKLVKGRVQIGSNSWVFPNVLIMPGVTLAEGAVVYPGSVVTKNIPSYEVWGGSPA
                     KFICHRKRDIKYEASFPVWFAI"
     CDS             13528..14517
                     /note="kp5F"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAI43765.1"
                     /translation="MSVRSVMIAWVSFQRRADVMKEFWEYSDYYITTKFRHKLLKPLD
                     YLIKIIKTINILAREKPDVVWMQLPPTFMVFVGIAYKRLRRNSVFLIGDFHNSALRPK
                     WFNFPFVRSALNRIDILVAHNEQVKTELIYKGINKKNVFVLEDMPFSYSTGNSVPVKN
                     TILFPCSFDVDEPLDVVLCAAKELPHITFNITGNHNGKISPDVIKLAPDNVIFTGYLT
                     KKAYDDLFLSSSVILGLTTRDNVQLSVSNEALSADKPMVLSDTTTLRNLFGDAAIFVE
                     SLDAKSISMGCVYAVEHTQELHVKTKILKSERKNRWKYQAEKIKRKITDFNAI"
     CDS             14530..14976
                     /note="kp5G"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAI43766.1"
                     /translation="MGRILFVSSGGGHWVQLTRIIKELKLERHEFHIASTSDGIRCLG
                     KDVKTIPDFNKSKPFKILMGSIIILLYIFKIRPTLAISTGAAPGLLCLLFTRLLGGKT
                     IWIDSIANTEKLSLSGRLARFFSNQVLTQWDHLGDGKKISYHGRVI"
     CDS             14976..15470
                     /note="kp5H"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAI43767.1"
                     /translation="MIFCSVGTQLPFSRLVDYLYRWSEFVNKQQKRIVIQSGGEVNSK
                     KLDNILVRMFVSEEEFSKYIDECSVFISHAGMGNIIRAIELNKPIVIVPRLGSLNEHR
                     NDHQTDSANRFSSLSNVFVANDFDSFCKAIELASGYCDNRSKTAYPERDKLIKYLNSQ
                     ISLL"
     gene            15747..17150
                     /gene="wcaJ"
     CDS             15747..17150
                     /gene="wcaJ"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAI43768.1"
                     /translation="MSTFNHRNRSNANASLISMAQRFSDVIIIFFGLYLVCIINSINF
                     DYHHILMPLLALAIFQMIGGITDFYRSWRGVAFSTEFNLFLKNWSFCSLITLGLLSLD
                     SSTVMNFYFFIQWYFFVSIGFLACRLSIRLLAGILRKLGYNTRRVAVVGSLPAGVDLL
                     KGFIEAPWLGFVVSGIYDDEPRSDIDYANIPYAGTTEELIINARDGKIDRIYIAMSMK
                     DEVKINNIVSQLADTTCSVLLIPDVFTFNILQSRTEEINGLPVVPLFDSPLNGINMVF
                     KRLEDILVSSIILLFISPILLIISLAVKLSSNGPVIFKQIRYGMDGKPIQVWKFRSMT
                     VMENDDKVVQATKNDIRVTKVGKFLRSTSLDELPQFFNVLFGQMSVVGPRPHAVSHNE
                     QYRTLIQGYMLRHKVKPGITGLAQINGWRGETDTLEKMEKRVEYDLLYIRGWSIWLDL
                     KIIFLTIFKGFINKSAY"
     gene            17314..18720
                     /gene="gnd"
     CDS             17314..18720
                     /gene="gnd"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAI43769.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVQEFVESLETPRRILLMVKAGAGTDSAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILKQIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLALSNEELAQT
                     FTEWNEGELSSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAQNAGIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRTDKEGVFHTEWLE"
     gene            18963..20378
                     /gene="manC"
     CDS             18963..20378
                     /gene="manC"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="BAI43770.1"
                     /translation="MLLPVIMAGGTGSRLWPMSRELYPKQFLRLYGQNSMLQETITRL
                     SGLEIHEPMVICNEEHRFLVAEQLRQLNKLSNNIILEPVGRNTAPAIALAALQATRHG
                     DDPLMLVLAADHIINNQPVFHDAIRVAEQYADEGHLVTFGIVPNAPETGYGYIQRGVA
                     LTDSAHTPYQVARFVEKPDRERAEAYLASGEYYWNSGMFMFRAKKYLSELAKFRPDIL
                     EACQAAVNAADNGSDFISIPHDIFCECPDESVDYAVMEKTADAVVVGLDADWSDVGSW
                     SALWEVSPKDEQGNVLSGDAWVHNSENCYINSDEKLVAAIGVENLVIVSTKDAVLVMN
                     RERSQDVKKAVEFLKQNQRSEYKRHREIYRPWGRCDVVVQTPRFNVNRITVKPGGAFS
                     MQMHHHRAEHWVILAGTGQVTVNGKQFLLTENQSTFIPIGAEHSLENPGRIPLEVLEI
                     QSGSYLGEDDIIRIKDQYGRC"
     gene            20401..21771
                     /gene="manB"
     CDS             20401..21771
                     /gene="manB"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="BAI43771.1"
                     /translation="MTQLTCFKAYDIRGELGEELNEDIAYRIGRAYGEFLKPGKIVVG
                     GDVRLTSESLKLALARGLMDAGTDVLDIGLSGTEEIYFATFHLGVDGGIEVTASHNPM
                     NYNGMKLVRENAKPISGDTGLRDIQRLAEENQFPPVDPARRGTLCQISVLKEYVDHLM
                     GYVDLANFTRPLKLVVNSGNGAAGHVIDEVEKRFAAAGAPVTFIKVHHQPDGHFPNGI
                     PNPLLPECRQDTADAVRTHQADMGIAFDGDFDRCFLFDDEASFIEGYYIVGLLAEAFL
                     QKQPGAKIIHDPRLTWNTVDIVTRSGGQPVMSKTGHAFIKERMRQEDAIYGGEMSAHH
                     YFRDFAYCDSGMIPWLLVAELLCLKNSSLKSLVADRQAAFPASGEINRKLGNAAEAIA
                     RIRAQYEPAAAHIDTTDGISIEYPEWRFNLRTSNTEPVVRLNVESRADTALMNAKTEE
                     ILALLK"
     gene            21935..23101
                     /gene="ugd"
     CDS             21935..23101
                     /gene="ugd"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAI43772.1"
                     /translation="MKITISGTGYVGLSNGVLIAQNHEVVALDIVQAKVDMLNQKISP
                     IVDKEIQEYLAEKPLNFRATTDKHDAYRNADYVIIATPTDYDPKTNYFNTSTVEAVIR
                     DVTEINPNAVMIIKSTIPVGFTRDIKERLGIDNVIFSPEFLREGRALYDNLHPSRIVI
                     GERSARAERFADLLKEGAIKQDIPTLFTDSTEAEAIKLFANTYLALRVAYFNELDSYA
                     ESQGLNSKQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYESVPNNIIAAI
                     VDANRTRKDFIADSILARKPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGIPVII
                     YEPVMQEDEFFNSRVVRDLNAFKQEADVIISNRMAEELADVADKVYTRDLFGND"
BASE COUNT     6473 a   4533 c   5439 g   6656 t
ORIGIN
        1 atgaatatgg cgaatttgaa agcggttatt ccggtcgcag gactaggcat gcatatgctg
       61 ccggccacaa aggcaattcc aaaggagatg ctgccgatcg ttgataagcc aatgattcag
      121 tacatcgttg acgaaatcgt cgccgccggg atcaaagaga ttgttctggt gacgcactcc
      181 tcgaagaacg cggtggaaaa ccacttcgac acctcctacg agctggaagc cctgctggaa
      241 cagcgcgtga agcgccagct actggcggaa gtgcaggcca tttgcccgcc gggcgtgacc
      301 atcatgaacg tgcgtcaggc gcagccgctg ggcctgggcc actctatcct ctgcgcccgc
      361 ccggtagtcg gcgacaaccc gtttgtggtg gtcctgccgg atatcatcct tgacggcggc
      421 accgctgacc cgctgcgcta taacctcgcc gctatgatcg cccgctttaa cgagaccggc
      481 cgcagccagg tgctggcgaa acgcatgccg ggcgatctct ccgaatactc cgtcatccag
      541 accaaagagc cgatggtggc tgaaggccag gtggcgcgta tcgtcgagtt tattgaaaaa
      601 ccggacgaac cgcagaccct ggactccgat ctgatggcgg tggggcgcta cgtgctgtcg
      661 gcggatatct gggccgaact ggaacgtacc gagccgggcg catggggccg tatccagctg
      721 accgacgcca ttgccgaact ggcgaagaag cagtccgtcg acgcgatgct gatgaccggc
      781 gaaagctacg actgcgggaa gaaaatgggc tacatgcagg ccttcgtcac ctacgggttg
      841 cgtaacctga aagaaggcgc caaattccgc gaaagcatta aaaatctgct ggcctgattg
      901 ctagcgtagt acgggggggc agggcgtgaa cattcgtcct gccactcata acgttatgca
      961 gaaattattc ataacgcgaa tgttataacg attgtaaaga aacgtatggc ttcggagact
     1021 tctggtagtt tgtctctggc ctctgtggtg caatggtcgg agtagcggca ataatgcttt
     1081 atgaatagtc acttagtgcg acaattccta aagcgcaggg aaagcggtca acgtcagcca
     1141 aaaataaaac ttgactgcga tcatgtttcc gctttaaaca tctcacttgc atgcataaaa
     1201 atgtgaaatg aattggcatg cgagctggta cagacattac ggataatccc tgtgcacggc
     1261 agtggacatc atcgaaggat cacaggtata tgaactggca actcatctca ttttttggcg
     1321 atagcactgt tttgctgccc agcgcagcgg cgctgtttat tgtcctgatg ctgcgtaaaa
     1381 cgtcgcggtt gctggcgtgg caatggagtt tgctgttcgg catcaccggc gctatcgtct
     1441 gcgcctccaa actggccttt atgggctggg gtctgggtat tcgcgagctg gattacaccg
     1501 gcttcagcgg ccactccgcg ctctccgcgg ccttctggcc tatcttcctg tggctgctca
     1561 gcgcccgtat ctccgtcggt ctgcgtaaag tggccgttat taccggctat gttctggccg
     1621 ccgtggtggg ctattcgcgg ctggtcatcc atgcgcattc cgtctcggaa gtgattgccg
     1681 gcctgctgct gggcgctgct ggcagcgctt tgttcctggt gttgcaaaaa cgtacctctg
     1741 atccggaaag cgtgaatatc tcatggggcg gtgtcgcatg cctggtgatg gttccactta
     1801 tccttttaca tagcggtagc aaagcgccga ctcagtccct gctgggacaa atcgccaccg
     1861 cggtggggcc gctggataaa ccctttacgc gtaccgatct gcacaagcag gcctggtaat
     1921 cgccatttgt tttacagggg aaattaagtt ttcgccggtt aaatagacaa ataagaaaat
     1981 aatctactat atgacaggca attgataatt catatttatg aaataatgaa gtgctactac
     2041 attactattg catatttgac tggatattgc gggaatgaga cgtttctcaa atgcactcag
     2101 aaaggacctg aagcacgtct gctgaatatt ccgataccag gaaactatta gaaattgtag
     2161 ttgacttaga cgccatcatc tgattttcta atgacgcgtt ctttccgtaa aatatgttgt
     2221 tttacagatg gttagcttca tgcttgatag tgtggcaaca acgctgcgct gcgtggtcgt
     2281 gtaacgtagt gaataatctt aagggttaac ctgcttattt tcgccaataa aagggcaggc
     2341 ggcattaatt ggcagatatt cggtcacaag actcccaatt gtgaccgaaa tcccgtagac
     2401 ttaacgccga aaaaataaag gcctgaccaa tttatcaccc acaggccgat taaatacgcc
     2461 gttcaggtag tcagtgcgct ggtagctgtt aagccagggg cggtagcgtc gctgaaatcg
     2521 cctgctgcac caaaaaaaac tttctttgta tggctataaa aatcgacaca ctatcggtga
     2581 ttaacgctat gagatatcta tggtgcttat cagatatcct caaaagcggg tcaggggcgg
     2641 ctgctgatat cacctgtaaa ccaactttcc catctcatcc atagcctgta gggtaaaatt
     2701 cgcctacatt gtgagctgag tggatgttat aaaggtgaca agcagcttag ggtaactgta
     2761 cttgcctcga cggtgttgca cagtgaagtc agctggtgcc gcgagtgctt tctatcttgg
     2821 tattcccctc attctcattg agatacgaca gcggggctga aaatggatct tgtacaatga
     2881 taaaaattgc gcgcattgcc gtgacgttgg gtttgctttc ctccctggga gcccaggcct
     2941 acgcggccgg gttagtggta aatgataacg atctgcgtaa cgacctggcc tggctttccg
     3001 atcgcggggt catccatctg agcctgtcga cgtggccgct gagccaggaa gagatcgccc
     3061 gtgcgttaaa aaaggccaaa ccgtcctatt cttctgagca agtggtgctg gcgcgtatta
     3121 accagcggct gtctgcctta aaagcggatt tccgggtcac cggctacacc tcaaccgatc
     3181 agccgggcac tccgcaggga tttggccaga cgcagccagc agataactcg ttaggcctgg
     3241 cgttcaacaa cagcggcgag tggtgggata tccatctcca gggcaacgtt gaagggggag
     3301 agcggatcag caacggatcg cgcttcaacg ccaacggcgc ctacggcgcg gtgaagttct
     3361 ggaaccagtg gctctccttt ggtcaggtac cacagtggtg ggggccgggt tatgaaggca
     3421 gtctgatccg cggcgatgca gccagaccaa tgaccggttt tttaatgcag cgcgcagagc
     3481 aagctgctcc ggagacatgg tggctacgct ggattggtcc gtggcagtat caaatttccg
     3541 ccagtcagat gaataagtat actgcggtgc cgcataccaa aatcattggt ggtcgtttga
     3601 ccttctcacc attccagtcg ctggaacttg gtgcctcacg cattatgcag tggggtgggg
     3661 aagggcgacc acaatcgttt agtagcttct gggatgggtt taccggtcag gataataccg
     3721 gcaccgacaa tgaaccaggt aaccagctag ctggtttcga ttttaaattc aaactcgagc
     3781 cgacacttgg ttggccgatc agtgtctatg gccagatggt tggtgaggat gaagcgggct
     3841 atctgccttc cgctaatatg tatcttgccg gggttgaagg gcatcatgct tggggcaaaa
     3901 atgccgttaa ctggtatgta gagacccatg acactcgtga tgacaggagt cgtacagatt
     3961 atatttatac ccaccacatc tataaagatg gttactacca acagggttac ccattgggtg
     4021 atgcaatggg aggggatggc caattagtgg ctggaaaagt cgaactggta acggaagata
     4081 atcagcgatg gagtacacgc ttggtatatg cgaaagtcaa tcctgaaaat caattgatta
     4141 ataaagcatt ccctcactcg gatactttga aaggggttca actgggctgg agtggcgatg
     4201 tttataagtc ggttcgcctg aatacaaatc tttggtacac caatgccgat aacagtgata
     4261 gtgatgatat aggcgccagt gccgggatag agattccgtt tagtttatag aatgagagct
     4321 atgtaatgag cgggaaaact agtggttgga cagaaaatag cttcaagcta gtagcgactc
     4381 aaagcagcaa ctcagaactt ggtaaaattt gaattattga tgatgtgaca ttatgaagaa
     4441 aaaaattatt agggtttcag cagtggcgtt agcaatgagt cttttggtgg gttgtaccat
     4501 tgttccaggg cagggattaa atagcttgcg caagaacaca gtggaactcc cggatagtga
     4561 ctatgatttg gataaactga taaatgttta tccgatgacg ccaggcttga ttgatcaact
     4621 gcgtccagaa actattctgg ctcgacctaa cccgcagttg gatagcttac ttcaaagcta
     4681 tgaatatcgt attggaattg gtgatgtgtt gatggtcacg gtatgggatc atccggaact
     4741 gactaccccc gcagggcaat accgtagcgc tagcgataca ggcaactggg tcaattctga
     4801 cggtactata ttctacccgt atattggtaa agtccaggtg gcaggaaaaa ccctcagtca
     4861 agtacgtcaa gatatcgcta gtcgtttgac tacttacatt gaaagccctc aagttgacgt
     4921 tagcattgct gcatttcgtt cccaaaaggc atatgtgacg ggcgaagtcg taaaatcagg
     4981 acaacagcca atcacgaata ttccattaac tgttatggat gccattaata ctgctggtgg
     5041 tcttgcgcct gatgctgatt ggcgaaatgt agttcttacg cataatggta aggatacaaa
     5101 aatctcatta tatgcgttaa tgcaaaaagg cgatctaacc caaaaccacc tcctttatcc
     5161 tggggatatt ttgtttgttc ctcgaaatga cgacttgaaa gtgtttgtaa tgggagaggt
     5221 tggcaaacag agtactttaa aaatggatcg cagtggtatg actgtagctg aagcgctagg
     5281 aaatgccgaa ggtatgtcac agacatttag tgatgctaca ggagtctttg ttattcgaca
     5341 gttaaaagat gataagcaag gtaaaatcgc taatatttat caacttaatg ctcaagatgc
     5401 ttcagcaatg gtactgggta cagaattcca gttacaacca tatgacattg tttatgttac
     5461 tactgctcct attgttcgtt ggaatcgcgt gatttcccag ttggtaccaa caataactgg
     5521 tgtccatgat atgactgaaa ccggcaagtt tattagaact tggtgataga aatgtttgac
     5581 agaattctta ttgtatgcac tgggaatatt tgtcgttcgc ccatagggga gcgctttctc
     5641 aggaatttgt tacctaataa aaaaattgac tcggcgggta ttggagcact cgttaatcat
     5701 acagcagatc ctagcgcagt gaaaattgcc gctcagcatg gaatctcttt ggaggggcat
     5761 agtggacagc agtttacttc ctctttgggg cgacaatatg atttgatttt agtaatggaa
     5821 aaatatcact tagaacaaat tggtcggatt gctccagagg caagaggtaa aacaatgctt
     5881 tttggacatt ggatagatca acgggaaatc ccggatccct ataaaaaaag cgaagaagcg
     5941 ttcctgtctg tctataaatt aattgagcaa gccggaaagt actgggctaa aaaactaagc
     6001 gcataaaatc aggaattagg ttatgtcatc atcagctaac aaaacgaatg tgaacgatgc
     6061 gagtgaaatc gatttatcta gattagttgg agagctaatc gatcatcgaa aattaattat
     6121 atcggtcact tcattattta cattaatagc aattatttat gcactttttg caactcctat
     6181 atatcaagct gatgctctcg ttcaggttga gcagaagcaa gccaatgcca tactaagtaa
     6241 tattagccaa atgcttcctg atagccaacc gcaatctgcc ccagaaattg cattattaca
     6301 atctcgtatg atcctcggaa agacggtaga tgatttaaac ttacaaactg aaattcagca
     6361 aaattattta ccgttaattg gccgtgggat agcccggatt actggggaaa aaagtggaga
     6421 ggtttcgatc tcacatttaa atatgcccct atctgagaat aacgatcaac caatagaatt
     6481 gacgctaaag gtattagggg acaatagata tttattatca ggtgatgatt ttagtattaa
     6541 tggaatagta ggtgaattag tagatggtaa agcgatctca ataaaaattg ataaaataaa
     6601 tgctgatgtt ggtgctgaat tcacaattag ctatatttct aaattgcaag caataactga
     6661 gttgcaaaaa tatcttaatg ttactgaaca agggaaggat acaggtattt taaatgtttc
     6721 gttgattggt gatgatgctt cattaattaa aaaaactgta gacagtatta ctaataatta
     6781 tttaactcaa aatattgcaa ggcaagcagc acaagatgaa aaaagtttag agtttttaga
     6841 caatcaactg ccaaaagttc gaaatgaact tgatttagct gaagataaat tgaatgcatt
     6901 tcgcaaaaaa aatgactcgg tagatttatc gctagaagca aaatcagttc ttgatcaaat
     6961 tgttaatgta gacaatcagt taaatgaatt aacatttaga gagtcagaaa tatctcagct
     7021 ttatactaaa gaacatccga catataaagc attaatggag aagagaaaaa cattacaaga
     7081 tgaaaaagct aaactaaata aacgagtttc agcaatgccg gaaacacagc aagacatact
     7141 tcgattgagt cgagatgttg aatctggtcg tgcagtatat atgcaattac tgaatcgtca
     7201 gcaggagtta aatattgcaa aatcaagtgc aataggtaac gtacgcatta ttgatgaagc
     7261 tgtaactcag ccaaaacccg tcaaacctaa taaaatatta gtggtgttaa ttggtgtaat
     7321 tcttggaggg gttgtatctg ttggcttagt tctcgttcgt gtgttcttac gtcgagggat
     7381 tgaaacacca gaacaactag aagaactggg gattaatgtt tatgcaagca tccccgtttc
     7441 agaagaatat gctaagaaag cagataaaac tcggaattgg agtaagaata agcttgagca
     7501 aaaaaatgct ttattagcat tggataatcc cgctgattta gcaatagaat caattagagg
     7561 gcttaggacc agcctccatt ttgcaatgat ggaagctagg aataatgtat taatgatttc
     7621 gggggcaagc ccgaatgcag gaaaaacttt cgtgagctct aacttagcag cagttattgc
     7681 acaaacaggt aagaaggttc tctatattga tgtagatatg cgtaaagggt acacacatag
     7741 actattcaat gtgagtaatg ataatgggct atcagatata ttatctggga aaattgaaat
     7801 atcgaaagct ataaaaaaaa tagactcaat tggttttgat tttatatcaa gaggaatggt
     7861 accaccaaat cctgctgagt tgctgatgca tcgtcatttc ggagaggtga ttaattgggc
     7921 cagttcacat tatgatatcg ttgttttgga tacacctcca attctcgcag taacagatgc
     7981 cgcaataata ggtaactatg ttggcaccac actgttgatc gcacgatttg aacaaaatac
     8041 agccaaagaa attgaaatta gtgttaagag atttgagcac agcggtgtta gcgttaaagg
     8101 ttgtatactc aatggtgttg tgaagaaggc aagtaactat tattcatatg gatatagtag
     8161 ttatggatat tcatacacag atgaaaaata gttattgaaa tatcaggtaa ttcttcgacg
     8221 aattacctgt ttttcagcgg gtttgagctc catagaaatg aataaataag aaagagttca
     8281 ataggaaaat aaaaggaata tgaatgataa ttaattatgt agttggagtg tgtataggga
     8341 aaaaatgtaa taggaaataa gaatatgttt tttataatct tctcgatgtt catagtgttt
     8401 tctattataa tgttgattgg ctcgccaaaa aaatcttttt ttatatttct tttgattata
     8461 gccattatac ctacagggaa ctcctacgca gattttatat cgctgcaagg ggtgtactat
     8521 tttgatttct atctgattgg tttttttata ctaatactta aaagcatcat gagttatagt
     8581 agtgagaaaa atatctctat tccgtactcg actcttttcg gtatttttac atatctatgt
     8641 attatacttg tgtctgttgt cagtaataat attgtagata aatatctatt aaaagatatt
     8701 cggccagtta taatgatttt tacagctgtt tatttctctg ggttagtgct gaggattgat
     8761 ggctataata aaaatacaat atttaagatc ttgtttgtaa tgtttatatt tagcattatt
     8821 catctgatat taccgagact tggagtatca gtgtataaag atgaatatta tgaagataac
     8881 tcttatagat atcttgatgc atcaacttac gttgcagcga tatacattat caattatttt
     8941 actagcaaca tgaagaatga atgtggaaaa tgggctagat tatgtttcta tgcagcaatt
     9001 ctttgtgtgc tagttggtaa ctcccgcttt atgcttttgg ccatcttcgc aagtataatc
     9061 tttgttagcg ttaaagatgt aaagaaaatg gctatatact ccctatccgc tattcttgtt
     9121 gctggtcttt ttttaggggt gagtgtttat gttggtgctg atagggtggt aaatggattt
     9181 tcaggcgatg tactgctctt ccagatcact aacagattct cacctgctct aagtttaatt
     9241 gataaaatgt catggtataa ctatatattt ggattgggag ctggaacata ttttgatatc
     9301 ccgtggtttg cataccgtgg tcttgaaacc caaaacattt ccgttgatag cttatattta
     9361 acaatgtatg ttaaatatgg attgtttgga cttatgctta ttgctttatt tacaaaggtt
     9421 gctgttaatg gtcttaaagc aaacgtaaaa aaagcagtta taatattttg tttaataatg
     9481 tattttgtgt cagctatacc ttatcaccct tattccttag ggattattgt tgggggagcc
     9541 gttatgatat tacttaacag aaaagaagtt gtatagggta tatgcatatg caaaataatt
     9601 caattttatc gagattgtta aaagactcaa cctggagtat gatttcaact tttgcaaata
     9661 agatttcatt tgttattgtt ggaattattg tggctagaat tttaggagca gaaaagtttg
     9721 ctatatttgc gataatacaa agcgtggtag tgatgctcgc gaatgttttc tctcaatcga
     9781 taacaaccgc cacctctaag catatagctg aatatataga atttgataaa aataaggtag
     9841 gcgcgggaat cgtggcaaca ttaatttttt ctatgttgtt cgcatcaact atttgtcttt
     9901 gcgccaattt ttttcctaat gaattttcta tatacttgct gtttcatgaa gactatttga
     9961 tatttgttag cagtacagct ggtattattg ttcttacgat tggattgggg tgggttcagg
    10021 gcgttttttc cggttttaga aattttaaat taaatgcagc gatcaatttg ctttatgcag
    10081 gtatatccgt accatttgca tatgtattaa catctaaata tggtgttagc ggagcgtttt
    10141 atagcgtaat tattagccag tcagtaactc ttattataag tacccttttt atatttttta
    10201 tacttaaaaa aaatcatgtc agatttatta ttaaaagttc atggcgagaa agaggagtta
    10261 ttacccatgt agggttgcca gttttcctca ccggcattat tgttgctcct attacgtggt
    10321 attctaataa gctattgtca gtcctttcag atggtcttaa ccaacttgcg gtttttgctg
    10381 catcaatgca atggagttct atttttacgc aagtttctgt tgtgctaggc gctgttttaa
    10441 ttcctatgtt ggctgcaaat aaagataaaa acaatgagtt gctagataga attaatttct
    10501 attcgagttg gctttttacg ataatatgca cagtgcctct tattattttt gttgacttgt
    10561 ttgtaaggat ttatgggaag tttaatttaa cctctgactt taaagttagc gtaatatttg
    10621 tattatttag cgcaatttta acatcattta aggggggggt tgctagaaaa ataattatat
    10681 taaatctatc atggttcagc gtgctgagca atttaggatg ggcgtttata tttgtagcgt
    10741 tgacttggaa aactaaaaaa tatggagctg ttggaattac tggtgcgttg tttttttcac
    10801 agtttataca tttcataatt acaatacctt attttttaaa aaggaagatt attgacatat
    10861 ccatgatttt taatatacat gtcttaactt tgatttttgt gcccatgatt tctatttatg
    10921 taagctttcg aattgacagc ctgattctta aagctatagc atgtgttgtt attatggttt
    10981 tttcagtatt caaatctata gatttgataa aaataaggaa gtaaatcgtt catgaaaaaa
    11041 aataaagtat atattcgtgg cgcgtatgcc cctggtaata tcggtgatga tgtactgatg
    11101 ttgagtgtta taaatatagt aaagaaggta gtgccggaaa aatttatttc agtaggggtt
    11161 gaacacccat cactagcaag aaaatataat tctaatattg actggataca tataaaaaaa
    11221 cctatctcag cggatgttgt tgtgtttggt gggggggggc aatttttttc atttaaccca
    11281 cctcccggag tcaaatcgag tttaatttct aaagttataa aatctataaa agcccaagaa
    11341 aatctattca ctgcgataga acgactgatg gtatcctcgt gcggcgggtt agataaaatt
    11401 tatataccaa ggaaacttgc tgcattttgt attggcttag ggccatttga taatcacggc
    11461 aagggatatc agcgtgcagt agaaataata aataaatgtg actatgtttc ggttagggat
    11521 gataaaagta aatcctattg taaaatgctt ggcaatgagt ctgtttcaga atttactgat
    11581 cctactttat tatctgacat ttggtaccct aatcagataa aaaagccata ctattctgac
    11641 aaggggtata tctcaattgt attaagagat tggccacatg ataagaatgg gcaggatttt
    11701 actaaagagt tgattaaatt tggtaactat ttgattaata atggtgaaaa ggttcggttc
    11761 gtatcagtgt ataaagaacg tgaagaggac ttaattgcaa aaaatgataa tattgactgg
    11821 ctggtttggg atgcaagaaa ctattcgata gttgaattca tgaatgaatt cgttggcaat
    11881 agtgaagtta tcatcagctc tagagcgcat ggtgtactgc ttcctgcttc tttaggtgta
    11941 ccaacaattg ctgttgcaat tgagaataaa ctgctaaaag ttcatgatat gatttcggac
    12001 ggaaatatta tagtgaaaat agcggaacat aaagcttttg atgaagcatt gacctgtttc
    12061 aggaaagata aagaacagtt gagagttaat ttggaacaag agataactaa aaatcatcaa
    12121 aaggtgaaag atgcaattga tgaatttaca aaatggctta aggataacgt ttgatcttaa
    12181 cgttatctgc atagccttat ctttaataat gcctagacaa tctttagcag atgagttgga
    12241 ttttaaaaaa ttaggtctta acgatacttt taaacaagat attctgaata ttgaagggat
    12301 ccggaattat tatgtattcg atgaaaagga aggtgcgttc agagtgtatt atccagcagg
    12361 ttcctttgat cctcaatcga tgaaaagtaa acatcttcca tctggaggga tgaattttaa
    12421 atgggccccg ttttatagta gaaataagga atgtgctatt atacagtatt ctgttcgatt
    12481 tcctaaatct tttgatttcg ttaaaggggg aaagttacca ggtctatatg gtggaaatgg
    12541 aaatactgga ggaaaaatac caaacggata tgatggattc agtgttcgtt tactttgggt
    12601 agagaatggt atgggcaaag tttatgcata tcttcctcag gaagacaaaa aacagaagtg
    12661 gggggttgga ttatctggct tgccatggtt ttatcctcgc ggagaatggc aaaatataac
    12721 tcttaaagtt aagctcaata cggttaattt tcaaaatgga attgtgaagt tatgggttaa
    12781 caataaatta gttattgata ggcgggatgt tttattcaga aaaactccta atttaaaaat
    12841 cgacggcgtc ctgttttcaa ctttttttgg tggcaataat cctagttttg cgcctaagga
    12901 actccagtat cttgacttca aggatattaa aatatcggat tggttctcaa agcaaatgag
    12961 atgcgaacat gatgaaactg attaagttga atgctaaaaa agtgattata ggttttctaa
    13021 atgctatctt atcactatcg actttttttg tggttaggcg attcttgtta cgtgttttat
    13081 ttagagctat tgtgggaaat aagagtacgg ttcatcgcaa agttaaaata tttgatatcg
    13141 gcagtttatc aattggtaag cattcaacga ttaactatgg ctgctttctg gataatagag
    13201 gtgggttaga tattggtgat aatgttaata tctcgcattg cgttaaaatt tatacaatgg
    13261 gtcatgattt agatgatcca tttgcaaagc ttgtaaaagg aagagtacaa attgggtcaa
    13321 attcatgggt atttcctaat gtattaataa tgccaggtgt tactcttgca gaaggagctg
    13381 tcgtatatcc gggaagtgta gtaacaaaaa acattcctag ttatgaagtt tgggggggaa
    13441 gtccagccaa attcatatgc catagaaaac gtgacattaa atatgaagca tcttttcctg
    13501 tatggtttgc catttaatat ttaagaggtg tctgtgagat ccgttatgat tgcatgggtt
    13561 agctttcagc gaagagctga tgttatgaaa gaattttggg agtatagcga ttattatatt
    13621 actactaaat ttagacataa attattaaaa ccacttgatt atcttataaa gataatcaag
    13681 accataaata tattagcgcg tgaaaaacca gatgtagtgt ggatgcaatt acctccaaca
    13741 tttatggttt ttgtcggaat cgcttacaaa cgtttaagaa ggaacagtgt ttttttgatt
    13801 ggtgactttc ataatagtgc attaaggcca aaatggttta atttcccatt tgtacgttct
    13861 gcgcttaata gaatagatat tcttgttgct cataatgagc aggttaaaac tgagttgata
    13921 tataaaggca ttaataaaaa aaatgttttt gttcttgaag atatgccttt ctcatactca
    13981 actgggaata gtgtacctgt aaagaacact attttatttc cttgttcatt tgatgtcgat
    14041 gaacccctcg atgtcgtcct ttgtgctgcg aaagagcttc cacatataac tttcaatatt
    14101 accggaaacc ataatggaaa aatttctccc gatgtaataa aactagctcc tgacaatgta
    14161 atatttactg gatatttaac caaaaaggct tacgatgatt tgttcttatc tagtagcgta
    14221 attttggggt tgaccacacg tgataatgtg caactaagtg tttctaatga agctttaagt
    14281 gctgataaac caatggtttt atcagacact acaactcttc gaaacctatt tggtgatgct
    14341 gcgatttttg ttgaatccct tgacgctaag tctataagta tgggctgcgt ttatgctgtt
    14401 gagcataccc aagaattaca tgttaaaact aaaatattaa aatcagagcg taaaaacaga
    14461 tggaaatatc aggctgaaaa gatcaaaaga aaaataacgg atttcaacgc aatataacga
    14521 ggttataaga tgggacggat tttatttgtt agttctggtg gtgggcattg ggtccagttg
    14581 acacgaataa ttaaagaact aaaactggaa aggcatgaat ttcatatcgc ctctacttct
    14641 gatggaatta gatgtttagg gaaggatgta aaaactatac ctgatttcaa taaaagcaag
    14701 ccattcaaaa tattgatggg tagtattata attcttctat atatttttaa gatcaggcct
    14761 acactagcta tctcaacagg agcagctcct ggacttttat gtctgctttt tactagacta
    14821 ttaggaggaa aaactatttg gattgatagt atagcaaata ctgagaagtt atcattatct
    14881 ggaagactgg cacgattttt tagtaatcag gtcttgacac aatgggacca tcttggcgat
    14941 ggaaaaaaaa ttagttacca cgggcgggtt atttaatgat tttttgtagt gtaggcactc
    15001 aacttccttt ttctagatta gtggattatt tatatcgctg gtctgaattt gtaaacaaac
    15061 agcaaaagag aatagttata caatccggtg gtgaggttaa ttctaaaaaa ctagataata
    15121 ttttagtcag aatgtttgtc tctgaggaag aattttcaaa gtacattgat gaatgttcgg
    15181 tttttatttc tcatgcgggg atggggaata taattagggc tattgaatta aataaaccga
    15241 tagtaattgt tcctcgactt ggttcattaa atgaacatag aaatgatcat caaactgatt
    15301 ctgcgaaccg attctcttca ctaagtaatg tttttgtggc aaatgatttt gattcttttt
    15361 gtaaagccat tgagttagct agtggttatt gtgacaacag aagcaaaact gcttaccctg
    15421 aacgagataa attaataaaa tatcttaatt cacaaatatc ccttctgtag tgttgtaagt
    15481 tttatttcac ttttgatatt agcattgtta attttagttt tgtaacctat ggcagttaaa
    15541 taaatatttt tctcttaagt gataaatgat atcggttttg ctatggatat gcatataaaa
    15601 caatattttg ataatgcttg ttgattatgg tgaaatattt gattaaacat atatctacat
    15661 tatgattatt actatggctt attcagttag gatgtacata tagattgatt tgaggttatg
    15721 catgtctata tctaaaggaa atttccatgt ctacttttaa tcatcgcaat cgttcaaatg
    15781 ccaatgcctc attgatttca atggctcaac gcttctcgga tgtgattata atatttttcg
    15841 gtttgtattt ggtttgcata atcaattcta taaactttga ctatcatcat atattgatgc
    15901 cattattagc attagcaata tttcagatga taggaggaat tactgacttt tatcggtcgt
    15961 ggcgtggggt tgctttttcc actgaattta atttatttct taagaattgg tctttttgtt
    16021 ctttaattac tttggggctt ttgtctttag actcatctac tgtgatgaat ttttattttt
    16081 ttatccagtg gtattttttt gttagtatcg gattccttgc atgtcgttta tctattcgtt
    16141 tacttgcagg cattcttcgt aaacttggtt ataatacccg aagagtggct gttgttggat
    16201 ctttacccgc aggcgttgat ttacttaaag gctttattga ggcaccttgg ctcggctttg
    16261 ttgtcagtgg tatatatgat gatgaaccac gaagtgacat tgattatgca aatattccat
    16321 atgctggaac tacggaagag ttaattataa atgcacgaga tggtaaaatt gaccgcattt
    16381 atattgcgat gagcatgaaa gatgaggtga aaataaataa tattgtcagt caattagctg
    16441 atactacgtg ttcggttctt ttaattcctg acgttttcac ctttaacatt cttcagtcaa
    16501 ggacagagga gattaatggt ttgccagttg ttcctctatt tgattctcct ttgaatggca
    16561 tcaatatggt attcaaacgg cttgaggata ttttggtttc ttcgattatt ttgttattca
    16621 tttcgccaat tcttttaata atttcattgg cagtaaaatt aagctccaat ggtccggtta
    16681 tatttaaaca aattagatat ggtatggatg gcaaacctat ccaagtctgg aagtttcgct
    16741 ctatgactgt aatggagaat gatgataagg tagttcaggc aactaagaat gatatccggg
    16801 ttaccaaagt tggcaagttt ttgcggagca catcccttga tgaactccct cagtttttca
    16861 atgtgttgtt tgggcaaatg tctgttgtag gaccaagacc gcacgctgtt tcccataatg
    16921 aacagtaccg taccttgatt cagggatata tgcttcgaca caaagttaaa cctggtatta
    16981 caggattggc gcaaataaat ggctggcgtg gtgaaactga tacacttgaa aagatggaaa
    17041 aaagagttga gtatgacttg ttatacatcc gtggatggag tatttggcta gatcttaaaa
    17101 taatttttct aactattttt aagggtttta taaataaatc tgcatattag cttttgattt
    17161 tatattccgc gttgttcatt tctagttcta tagggttata ttttatgcca actaatcaat
    17221 tttcgctatg aggaccctat gctttcagct aacattatca tcacatttaa gctgtgcata
    17281 tgtcgcagtg accacacctg acaggagtat gtaatgtcca agcaacagat cggggttgtc
    17341 ggtatggcag tgatggggcg caaccttgcg ctaaacatcg aaagccgcgg ttataccgtc
    17401 tccattttca accgctcacg tgaaaagact gaagaagtga ttgccgaaaa tcccggcaag
    17461 aaactagttc cttactacac agtacaagag ttcgttgaat ccctcgaaac gccacgccgt
    17521 atcctgttga tggttaaggc tggagctggc accgacagtg ccatcgattc cctgaagccc
    17581 tacctcgaca aaggcgacat catcattgat ggcggcaaca ccttcttcca ggacaccatc
    17641 cgtcgtaacc gtgaactctc tgccgaaggt tttaacttta tcggtaccgg tgtttccggt
    17701 ggtgaagagg gggctctgaa agggccttcc atcatgcctg gtgggcagaa agaagcctat
    17761 gagttagttg ctccgattct gaagcagatt gctgcggttg ctgaagacgg tgagccatgt
    17821 gtcacctata tcggtgctga cggtgctggc cattatgtga agatggttca taacggcatc
    17881 gagtatggtg acatgcagct gattgctgaa gcttatgcgc ttttgaaagg cggtctggca
    17941 ctttccaacg aagagctggc gcaaaccttc accgaatgga acgaaggtga actcagcagc
    18001 tacctgatcg acattaccaa agatatcttc accaagaagg atgaagaagg taagtacctc
    18061 gttgatgtca ttcttgatga agcagcaaac aaaggtaccg gtaagtggac cagccagagc
    18121 tcactggatc tcggcgaacc tttgtctctg atcaccgagt ctgtatttgc tcgctatatt
    18181 tcttcgctta aagaccagcg tgtagccgcg tcgaaagtgc tgagtggtcc gcaggcccag
    18241 ccggccggtg ataaagctga atttatcgaa aaagtgcgtc gcgcgttgta cctcggtaaa
    18301 atcgtctcct atgctcaggg cttctcccag ctgcgtgctg cttctgatga atacaactgg
    18361 gatcttaact acggcgagat cgctaagatt ttccgcgctg gctgcatcat tcgtgcgcag
    18421 ttcctgcaaa agatcactga tgcttatgcg caaaacgctg gcattgctaa cctcctgctg
    18481 gcaccgtact tcaaacagat cgctgatgac tatcagcagg cgctgcgtga tgtcgtggcg
    18541 tatgccgtac agaatggtat tccggtaccg acgttctctg ccgcaatagc ttactacgat
    18601 agttatcgtt ccgcagttct gcccgctaac ctgattcagg ctcagcgtga ttactttggt
    18661 gcgcacacct ataagcgcac tgataaagaa ggtgtattcc ataccgagtg gttggaataa
    18721 tctttatata ccacagtcag gccaattggc ctgactgtta gctattggta gttattctac
    18781 aataatctga tcaaagttat cttatttgca cgtcttcgtc atttatccag ctctaataaa
    18841 gcaaattctt atcttttaag aatttgccat atttatactt ctgtacatct ataataagct
    18901 acttctggcc tcagaatata tctgggtgtt ttataacagg gttttaatta aaggatctta
    18961 atatgttgct tcctgtgata atggctggtg gtaccggcag tcgtctctgg ccgatgtctc
    19021 gcgagcttta tccgaaacag ttcctccggc tgtacgggca gaactccatg ctgcaggaaa
    19081 ccatcacccg actctcgggc cttgaaatcc atgaaccgat ggtcatctgt aacgaagagc
    19141 accgcttcct ggtggccgaa cagctgcgcc agctcaacaa gctgtcgaac aatattattc
    19201 ttgagccggt cgggcgcaac accgccccgg ccatcgccct ggcggccctt caggccaccc
    19261 gccacggcga cgacccgctg atgctggtcc tcgccgccga ccatatcatc aataaccagc
    19321 cggtcttcca cgacgccatc cgcgtcgccg agcagtatgc cgatgaaggc catctggtca
    19381 ccttcggtat cgtgccgaac gccccggaaa ccggctacgg ctacatccag cgcggcgtgg
    19441 ccctcaccga cagcgcccac accccgtacc aggtggcccg cttcgtggag aagccggacc
    19501 gcgagcgcgc cgaggcctac ctcgcctccg gggagtacta ctggaacagc ggcatgttta
    19561 tgttccgcgc caaaaaatac ctctccgagc tggccaaatt ccgcccggat atcctcgaag
    19621 cctgccaggc cgcagtaaat gccgccgata acggcagcga cttcatcagc attccgcatg
    19681 acattttctg cgagtgcccg gacgagtccg tcgactacgc ggtgatggag aaaaccgccg
    19741 acgcggtggt ggtcggtctc gatgccgact ggagcgacgt cggctcctgg tccgccctgt
    19801 gggaagtcag cccgaaagat gagcagggta acgtcctcag cggtgacgcg tgggtgcaca
    19861 acagcgaaaa ctgctacatc aacagcgacg agaagctggt ggcggccatc ggcgtggaga
    19921 acctggtgat tgtcagcacc aaggacgccg tgctggtgat gaaccgcgag cgttcccagg
    19981 acgtgaagaa ggcggtcgag ttcctcaagc agaaccagcg cagcgagtac aagcgccacc
    20041 gcgagattta ccgtccctgg ggccgctgcg acgtggtggt ccagaccccg cgcttcaacg
    20101 tcaaccgcat tacggtgaaa ccgggcggcg ccttctcgat gcagatgcac caccaccgcg
    20161 ccgagcactg ggtcattctc gccggcaccg gccaggtgac ggtcaacggc aagcagttcc
    20221 tgctgaccga gaaccagtcc acttttattc cgattggcgc cgagcacagc ctggaaaacc
    20281 cgggccgcat tccgctggaa gtgctggaga tccagtcggg gtcgtacctc ggcgaggacg
    20341 acattattcg tattaaagac cagtatggtc gttgctaatt ttttcgggac aaaacgcaga
    20401 atgacacagt taacatgctt taaggcttat gacatccgtg gtgaactggg cgaggagctg
    20461 aacgaggaca tcgcctaccg tatcggccgc gcctacggcg aatttctgaa acccgggaag
    20521 atagtggtgg ggggcgatgt gcgcctcacc agcgagtcgc tgaagctggc gctggcccgc
    20581 gggctgatgg acgccggcac cgacgtgctg gatatcggcc tgagcggcac ggaagagatt
    20641 tacttcgcca ctttccacct cggggtggat ggcggtatcg aggtgacggc gagccataac
    20701 ccgatgaact acaacggcat gaagctggtg cgcgagaacg cgaagccgat cagcggcgac
    20761 accggcctgc gggatatcca gcgcctggcg gaggagaacc agttcccgcc ggtggacccg
    20821 gcgcgtcgcg ggaccctgtg ccagatttcg gtgctgaagg agtacgtcga ccacctgatg
    20881 ggctacgtgg acctggcgaa cttcacccgt ccgctgaagc tggtggtgaa ctccggcaac
    20941 ggggcggcgg ggcacgtgat tgatgaagtg gagaaacgct tcgcggcggc cggggcgccg
    21001 gtgaccttta tcaaggtgca tcaccagccg gacggccatt tcccgaacgg tatcccgaac
    21061 ccgctgctgc cggagtgccg ccaggacacc gccgacgcgg tgcgtacgca tcaggcggac
    21121 atggggatcg cctttgacgg cgacttcgac cgctgtttcc tgttcgatga cgaggcgtcg
    21181 tttatcgagg ggtactacat tgtcggcctg ctggcggagg cgttcctgca gaaacagccg
    21241 ggggcgaaaa tcattcacga cccgcgtctg acgtggaaca cggtggacat cgtgacccgc
    21301 agcggcggcc agccggtgat gtcgaagacc gggcatgcgt tcatcaagga gcggatgcgc
    21361 caggaagacg ccatctacgg cggggagatg agcgcgcacc attacttccg cgacttcgcc
    21421 tactgcgaca gcgggatgat cccgtggctg ctggtggcgg agctgctgtg cctgaagaac
    21481 agttcgctga aatcgctggt ggcggaccgc caggcggcgt tcccggcgtc gggggagatc
    21541 aaccgcaagc tgggaaatgc ggcggaggcg atagcgcgca tccgggcgca gtatgagccc
    21601 gcggccgcac acatcgacac aacggacggt atcagtattg aataccctga gtggcgtttt
    21661 aacctgcgca cgtccaatac cgagccggtg gtgcgtctga acgttgagtc cagagcggat
    21721 actgcgttaa tgaatgcaaa aaccgaagag attttagctc ttctcaagta atgcattatc
    21781 cataatggaa gccatagggt cagattttaa tcatattatt gaccttatgg cttattcttg
    21841 acatcccact ggtcaaagcg taaaaccgcc cacagaatta tttaatttcg tggctatccg
    21901 ccattatcca gttaactgat taaagtgtaa tctcatgaaa attactattt ccggtacagg
    21961 ttatgttggt ttatcgaacg gtgtcctgat tgcgcaaaac cacgaagtgg tggccctgga
    22021 tatcgtacag gccaaagtgg atatgcttaa ccagaagatc tctccgattg tcgataaaga
    22081 gattcaggaa tatctggcag aaaaaccgtt aaatttccgt gccaccacgg ataagcacga
    22141 cgcataccgt aatgccgact acgtgatcat tgccacgccg accgactacg atcccaaaac
    22201 caactacttc aacacctcta cggtggaagc ggttattcgc gatgtcacag agatcaaccc
    22261 gaacgcggtg atgatcatta aatcgaccat cccggtgggg ttcacccgcg acatcaaaga
    22321 acgtttaggg attgataatg ttattttctc tcctgagttc ctgcgtgaag gacgtgcgct
    22381 gtacgacaac ctgcacccgt cgcgtattgt catcggtgaa cgctctgcgc gtgccgaacg
    22441 ttttgctgat ctgctgaaag aaggcgcgat caagcaggat atcccaaccc tgtttaccga
    22501 ctccaccgaa gcggaagcga tcaaactgtt cgctaacacc tatctggcgc tgcgcgttgc
    22561 ctatttcaat gagctcgaca gctatgctga aagccagggg ctgaacagca agcagattat
    22621 cgaaggggta tgcctggatc cgcgtatcgg caaccattat aacaacccgt cctttggcta
    22681 cggcggctac tgcctgccga aagataccaa gcagctgctg gcgaactacg aatcggtccc
    22741 gaacaatatc atcgcggcta tcgtcgatgc taaccgtacc cgtaaagact ttatcgcgga
    22801 ttctattctc gcccgtaagc cgaaagtggt gggtgtgtat cgcctgatca tgaagagtgg
    22861 ttcggacaac ttccgcgcct cttctattca gggcatcatg aagcgcatca aggcgaaagg
    22921 tattccggtc attatctatg agccggtgat gcaggaagat gagttcttca actcccgcgt
    22981 cgtgcgcgac ctgaatgcct tcaaacaaga ggcggatgtg atcatctcta accgtatggc
    23041 ggaagagctg gcggatgtgg cggacaaggt ttacacccgc gatctgtttg gtaacgatta
    23101 a
//
