LOCUS       AB924604               25830 bp    DNA     linear   BCT 28-OCT-2015
DEFINITION  Klebsiella sp. 265(1) DNA, capsular polysaccharide synthesis gene
            cluster, serotype: K68.
ACCESSION   AB924604
VERSION     AB924604.1
KEYWORDS    .
SOURCE      Klebsiella sp. 265(1)
  ORGANISM  Klebsiella sp. 265(1)
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella.
REFERENCE   1
  AUTHORS   Pan,Y.J., Lin,T.L., Chen,C.T., Chen,Y.Y., Hsieh,P.F., Hsu,C.R.,
            Wu,M.C. and Wang,J.T.
  TITLE     Genetic analysis of capsular polysaccharide synthesis gene clusters
            in 79 capsular types of Klebsiella spp
  JOURNAL   Sci Rep 5, 15573 (2015)
   PUBMED   26493302
  REMARK    DOI:10.1038/srep15573
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25830)
  AUTHORS   Pan,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2014) Contact:Yi-Jiun Pan National Taiwan
            University College of Medicine, Department of Microbiology; 1, Sec
            1, Jen-Ai Rd., Taipei 100, Taiwan
FEATURES             Location/Qualifiers
     source          1..25830
                     /organism="Klebsiella sp. 265(1)"
                     /mol_type="genomic DNA"
                     /strain="265(1)"
                     /serotype="K68"
                     /db_xref="taxon:1497836"
     gene            210..1151
                     /gene="galF"
     CDS             210..1151
                     /gene="galF"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose pyrophosphorylase"
                     /protein_id="BAT24260.1"
                     /translation="MRSDRHRKIYNLRMDMRMANLKAVIPVAGLGMHMLPATKAIPKE
                     MLPIVDKPMVQYIVDEIVAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQL
                     LAEVQAICPPGVTIMNVRQGQQLGLGHSILCARPIVGDNPFVVVLPDIVLDDASADPL
                     RYNLAAMVARFNETGRSQVLAKRMPGDLAEYSVIQTREPLETEGQIGRIVEFIEKPDE
                     PQTLDSDLMAVGRYVLSADVWSELERAEPGAWGRIQLTDAIAELAKKQSVDAMLMTGE
                     SYDCGKKMGYMQAFVNYGLRNHKEGNKFRESIKKLLA"
     gene            1600..2229
                     /gene="cpsACP"
     CDS             1600..2229
                     /gene="cpsACP"
                     /note="orf2"
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase homologue"
                     /protein_id="BAT24261.1"
                     /translation="MSWQFVSFFGDSTVLLPSAAVLLIVLFLRAPSRQVACHWALLFG
                     ITGAIVSASKLAFMGWGIGIRELDFTGFSGHTALSAAFWPIFLWLLFSRATTGVRRAA
                     VVVGYALAALVGYSRLMIHAHSTSEVVAGLLLGASGSALFLLLQSRISRAENVQLSWS
                     GVFSVMMIPVLLLNTGVKAPTQSLLGEIAVKIGPLEKPFTRADLHKHFY"
     gene            3258..4697
                     /gene="wzi"
     CDS             3258..4697
                     /gene="wzi"
                     /codon_start=1
                     /transl_table=11
                     /product="surface assembly of capsule"
                     /protein_id="BAT24262.1"
                     /translation="MMKIARIALALGLLTSVSSPVFAAGLVTNDNELRNDLSWLSDRG
                     VIQLSLSTWPLSQEEITRALKKAKPSYSSEQVVLARINERLSSLKADFRVSGYTSTDQ
                     PGTPQGFGQSQPADNSLSLAFNNSGEWWDVHLQGNVEGGERISNGSRFNANGAYGAVK
                     FWNQWLSFGQVQQWWGPGYEGSLIRGDAARPMTGFLMQRAEQAAPETWWLRWIGPWQY
                     QISASQMNQYTAVPHTKIIGGRLTFTPFQSLELGASRIMQWGGEGRPESFSNFWDGLT
                     GKDNTVSNDPNEPGNQLAGFDFRLKLEPTLGLPISLYGQMIGEDESGYLPSANMFLGG
                     VEGHHGWGKDAINWYFEAHDTRSNMSRTNYSYTHHIYKDGYYQQGYPLGDAMGGDGQL
                     FAGKVELVTEDNQRWSTRLVYAKVNPKNQSINKAFPYSDTLKGIQLGWSGDVYETVRL
                     NTNIWYTDADNSDSDDIGASAKIEIPFSF"
     gene            4821..5957
                     /gene="wza"
     CDS             4821..5957
                     /gene="wza"
                     /codon_start=1
                     /transl_table=11
                     /product="putative capsule polysaccharide export protein"
                     /protein_id="BAT24263.1"
                     /translation="MKKNIVRVSAVALAISFLTGCTIVPGQGLNSLRKEVVELPDSDY
                     DIDKLVNVYPMTPGLIDQLRPDNVVARPNPQLDSLLQNYEYRIGVGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNSDGTMFYPYIGKVKVAGKTLSQVRQEITSRLTTYIESPQ
                     VDVSIAAFRSQKTYVTGEVIKSGQQPITNIPLTVMDAINAAGGLATDADWRNVILTHN
                     GKDTKLSLYALMQKGDLTQNHLLYPGDILFVPRNDDLKVFVMGEVGKQSTMKMDRSGM
                     TLAEALGNAEGMSQSLSDATGVFVIRQLKGDKQGKIANIYQLNAQDASSMVLGTEFQL
                     QPYDIVYVTAAPLVRWNRVISNLVPTITGVHDLTETVRYIRTWP"
     gene            5960..6394
                     /gene="wzb"
     CDS             5960..6394
                     /gene="wzb"
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="BAT24264.1"
                     /translation="MFNSILVICTGNICRSPLGERYLRKMLPGKRIDSAGTGALVGHA
                     ADESASKIAALNGLSLDGHQGRQLIPSVAREYDLILAMEKVHLEYVSRIAPEVRGKTM
                     LFGHWLGQREIPDPYRKSEEAFVSVYSLIEQAGKNWAEKLGS"
     gene            6412..8571
                     /gene="wzc"
     CDS             6412..8571
                     /gene="wzc"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="BAT24265.1"
                     /translation="MSSAKNKTAVKDPDEIDLGRLIGELIDHRKLIVSVTSLFTLLAL
                     VYALFATPIYQADALVQVEQKQGNALLNSLSQILPDSQPQSASEIALLRSRMILGKTV
                     DDLNLQAKIEENYFPVFGRGLARLLGYKPNNLKISRLYLNIPGEDVPEIEIKVLDNKK
                     FSITGDGIELTGTVGELVEAKGLSLLVSEIGAEPGTTFTVSYIPRLKAITNLQDNLAI
                     VDEGKDTGILTLSLTGDDQAQIKNIIDGISTNYLAQNIARQAAQDAKSLEFLSEQLPK
                     VRSELDLAEDKLNGYRQQKDSVDLSLEAKAVLDQIVNVDNQLNELTIRESEVSQLFTK
                     EHPTYKALMEKRKILQEEKSKLNKRVSAMPETQQEVLRLSRDVDSGRVVYMQLLNRQQ
                     ELSIAKSSAIGNVRIIDTAITQPKPVKPNKVLVTLLGLIIGLLVSVGLVLARVVLRKG
                     IESPEQLEELGISVYASVPISEEFAKRVERTNKIKSRKPDEVAVFLAVENPADLAIES
                     IRGLRTSLHFAMMEARNNVLMITGASPNAGKTFISSNLAEVISQTGKKVLFIDADLRK
                     GYTHKLFNIDNNNGLSDILSGKTTMDLAVKNIPNIGFDFISRGMVPPNPAELLMHKRF
                     GELIDWANSRYDLVIVDTPPILAVTDAAVIGNYAGTTLLVARFEQNTAKEIEVSIKRF
                     EQSGVNIKGCILNGVVKKASNYYGYGYNHYGYTYTDK"
     gene            8605..10113
                     /gene="wbap"
     CDS             8605..10113
                     /gene="wbap"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT24266.1"
                     /translation="MPRFFYAEKIIYAHIINRTTRVYCEEVMRLIVKNALVSTTLALS
                     DFLGFIISPYLAILFLSVVLNNYQEVVPPRDIESWLGLHWLLGFCCVAWYSVRLRHYF
                     YRKTFWFELKEILRTLAIFAVIEIAVMAFTTWSFSRYLLVISWMLILVLVPLFRMVAK
                     KLLNMSGLWMRDTWIIGNGNNAYEAYKAITSEHNLGLRIVGFVEVSKPMVSQKTVFGV
                     PIIHASADWLNTIDKKNQFIVAVESTESEERNMWLRNFMIKGYRYVSVIPTLRGMPLD
                     STDMSFIFSHEVMIFRVQQNLAKWSSRLSKRLFDIVGSLSIIIVLSPLLIYISRKVKK
                     DGGPSIYGHERIGKGGKPFKCLKFRSMVINSKEVLDQLLNNDLEAKEEWDKTFKLKND
                     PRITKIGHFLRRTSLDELPQLFNVLKGEMSLVGPRPIITAELERYNDEVDYYLLSKPG
                     MTGLWQVSGRSDVDYETRVYLDAWYVKNWSMWNDIAILFKTIGVVLKKDGAY"
     gene            10176..11624
                     /gene="wzx"
     CDS             10176..11624
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAT24267.1"
                     /translation="MMTSSLKKTAVSGLIWSAIERFSVQGTQFIVTIILARLISPEDF
                     GLIGMITVFIALSDLIINGGFSQALIQKKQRTQDDFSTVFYFNIIIAVFIYGLIYYFA
                     PYVAKFYNQMPLIDILRILAISVVLKSFCVVQNAILSIKLNFKLRTKINLISALLSGI
                     LAIYMAYKGLGVYALIYQTIIFSLLVSVFSFALIRWFPSLIFSYDSLKVLFNFGSKLL
                     FASVVRTIVDNCYAILIGRFLSIRDVGYYTQGRNMPDVLSMNLYNVLQNVFFPLMSAH
                     QDDKERLLKIYKKGIQGTAFIIIPAMVGLMLIADPFVHCVLSDKWKGAIIVIQWVALS
                     RIIIPISALNCSIINAVGRSDIYLKIDLLKLPLTIGALLATFSFGLEVIVIGNVLVSA
                     ICFFINAYYPGKWFGFGAWEQLKKISPVIFCTLCMALPLYFIKLDNKLLEMILKLGIG
                     PIIYSIMCYLLKVETFMEMCTLLKSKIKKESA"
     gene            11621..12688
                     /gene="wclV"
     CDS             11621..12688
                     /gene="wclV"
                     /note="orf9"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvyl transferase"
                     /protein_id="BAT24268.1"
                     /translation="MKKVLAINECCSDNIGDHAINHGLQKLIMINSYEAQSVGFDAGV
                     KHEKPQKIATDNVHLSFRTRFKKKYLSGRQSLKYALWLIKNLLRVRSTVKNEHQAAII
                     GGGQLIQSGGTFPIAMFVWTFYCKKKNLPIYIAGVGCAEKFSKLDVWLYKVSFKRAKK
                     IFVRDVSSRDKLKSIFSTESELIPDLAYALYDEGTFFSDKKERTLIGCTSYYVYEKNI
                     KELSRKDGLTNSQYIDKWQSIVLSELNNKKEVILASTTVQDAVLNKLIYGRLVELGYS
                     SKIELVESIPSTYEYLALLNNVNKVISGRMHSLILGHISGCRIETIDINKKIDQFMFE
                     YSDKHPSELNANLNEKFKNII"
     gene            13013..13873
                     /gene="wckX"
     CDS             13013..13873
                     /gene="wckX"
                     /note="orf10"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT24269.1"
                     /translation="MAIEFVNKYFPWKAKIRYSLMLHGSEVLNLKNGRASIFPKIIDI
                     FGGTKNIYTNSNYTKNILHENHNVPSTIPVEVTYLGVSQTENLSNENYIANVKSERFQ
                     LLSVGRLDDRKGFDNVIKAIGLLDEAVKSKIYFTIVGNGSDEYKEILNDLAKQNKVNL
                     NILSGLNDNELNECYNRTNLFILAARNNNKKIEGFGLVFLEAAKFGVPSIATDVGAIK
                     EVVKNNKTGFVVKEDIHELMKAIYNCYIDRDILIEFSRNCITNVQEFKWSTLANKTFP
                     KIMVQKNEKY"
     gene            13794..14969
                     /gene="wckW"
     CDS             13794..14969
                     /gene="wckW"
                     /note="orf11"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT24270.1"
                     /translation="MCKNLNGRRWQIKPSPKLWFKKMKNINILYVDTCLDVAGGQRSL
                     IALLTNIASQINFSILIDEANKKYEQELLKAGISNNAIIKIKTCTVGGRALGGLMLFN
                     SVLRKAAKFDIIHCNTFYDGLFAMPAARLRGKKTIFRARCGIDLSNHGYIDNVIYNFS
                     TRILANSDYVKNTFRRVSSDLNKVISLYNPLDMKFHKEINPDVINFKHDVQKNYVIAV
                     VGAITEVKNQMEVLKALAQLKDTSIKLRFIGEPRSTEKDRKYYNDLLNYAKENNLLPQ
                     VEFTGFVSDVRDKLGDVNLVCVPSDREPLGRVIFESQLFGIPVLASDSGGNSELIEDG
                     STGYLYALGNVNELATKLLKVKDNNHQLALDAQRFVLKRFSPERTYLEELNLYHAIK"
     gene            15076..16317
                     /gene="wzy"
     CDS             15076..16317
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAT24271.1"
                     /translation="MALSIKKLNLNYALIIAFIVIILPQVILKPIGGDLSIVDIGAPL
                     IIAYCMFRYQLRLPPPQKYLLVFIFYLLVSYLVMMLFGGIEYQESSPYLIRMVSLYAP
                     IFLVPYLGNDETQFVKFGRVFVVISLIATVAIIFLYISGWTGVSAHQTTESDDGLKVN
                     RLGGLPGESGAFAYNILFVFYMSLIVYLVAAKKWLIKIVSFGLTLVVLFLSFKYSLAR
                     VIVICAGAVIVCGYFFTSMSLIKKYFLFLMTFLICSSAIFFVSPDSLDLSKYRLSNVA
                     STDMNSVSSGRVSHWIDAVTLYVESPFHVIFGVGHRMSVRFLGHAVENFFIQNLLDYG
                     IVGTILFIMFLWVLLKPIIKDSRANNSISVAVLLVFTGIFLQWQFNDINTYYQTYPAT
                     LFFLSWWSQICRKRNVTDENG"
     gene            16357..17775
                     /gene="manC"
     CDS             16357..17775
                     /gene="manC"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase"
                     /protein_id="BAT24272.1"
                     /translation="MITPVIMAGGTGSRLWPMSRELYPKQFLKLCGSNSMLQETIVRL
                     DGLDVSNPVLICNEQHRFLAAEQLRQIDCLSGDIILEPVGRNTAPAIALAALQAISGG
                     KDALLLILAADHIIDDISSFHEAVNKAIPHAKDGRLVTFGIVPSGPETGYGYIQRGSA
                     VQNHEQAYKVQRFVEKPDLKTANDYVISGEYYWNSGMFLFSAKKYLDELAKYRPDISN
                     ACEKSFSVVEKDSMQDFIRVDAEKFKLCPDESIDYAVMEKTEDAVVIPLDAGWNDVGS
                     WSALWDVNTKNNDNNALIGDVFTYNARDCYINTDEKFVAAIGVENLVIVNTKDATLVI
                     NKDKVQDVKKVVEFLKQDNRREYKIHRESYRPWGVQDKVVDTARYHVNKVTVKPGGKF
                     SLQKHIHRAEHWVVLSGTAEVTLGEQTYLLTENQSTFIPVGQTHMLHNPGKIPLVILE
                     IVSGTYLGDDDIIRLKDHYGHF"
     gene            17792..19168
                     /gene="manB"
     CDS             17792..19168
                     /gene="manB"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="BAT24273.1"
                     /translation="MTNKLSCFKAYDIRGKLGDELNEDIAYRIGRAYGEYLKPKEIVL
                     GGDVRLTSESLKLALANGLQDAGVDVIDIGLTGTEEIYFATSYLAIDGGIEVTASHNP
                     MDYNGMKLVKENSKPISGDTGLRHIQKLAEENAFPTVSANSRGSYKTMSILEPYIDKL
                     LSYVELSNFSKPLKLVLNSGNGAAGHVIDAIEERFRYNNLPIDIVKIHNNPDGHFPNG
                     IPNPLLPECRQDTIDAVIAHKADLGIAFDGDFDRCFLFDEKGNFIEGYYIVGLLAQAF
                     LEKEPGSKIIHDPRLSWNTIDLVSESGGIPVMSKTGHAFIKERMRLEDAIYGGEMSAH
                     HYFRDFAYCDSGMIPWLLVAELICNKNQSLNQLVSDRMKAYPASGEINSSLADPKAAI
                     ERVLEKYKADAVCIDHTDGISLEYPNWRFNLRSSNTEPVVRLNVESRGNRDLMVEKTN
                     EILALLRS"
     gene            19239..20378
                     /gene="wbaZ"
     CDS             19239..20378
                     /gene="wbaZ"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT24274.1"
                     /translation="MSGEINIGIVADWLVTYAGSEKVIKEFIDVFPSAELYSVVDFLS
                     DSNRALFAGKNAHTTFIQKMPFAKSKYQKYLPLMPLAIEQLDMSGYDVILSSSHAVAK
                     GVLTGPDQLHISYVHSPIRYAWDLQHQYLRESGLSNGLKGLIAKYLLHKIRLWDYRTA
                     NGVDHFIANSKFISRRIHKVYGRSSDVIYPPVDVKNFKLNENKEDYYFTASRLVPYKR
                     IDLIVDAFNEMPDKKLVVIGDGSEMHKIKSKAKKNIEILGYQPNNIMQEHMQNAKAFV
                     FAAEEDFGITPVEAQACGTPVIAFGKGGVLETINSIENTQPTGLFFDKQNPQCIIESV
                     KKFESMQDVFEPIECRRNAEKFSEERFRSEINAYVRDKWAMFNNC"
     gene            20409..21536
                     /gene="wcuC"
     CDS             20409..21536
                     /gene="wcuC"
                     /note="orf16"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="BAT24275.1"
                     /translation="MQSCFKLLDCEGYIMATSLSKKVRYLLLLLTLCHMTAVCAFEFG
                     IGTHIANYKESSEFYIQKVKSYGFNSVRDELYWNDVEKQNGVFSIPPNRTKTDHYFQN
                     LQSNNVSSLLVLDYGNNIHTRGGFPSNSQQIAQFASYAAWIAERYKGKVKYYEVWNEW
                     YLGTGISSWFLKKAKPDDAIYFQLIKATSEAIKRIDPGAKIIAGSFNPLKKPEIEWFD
                     NYIDMGVLKYIDGISVHPYSYGNKDIKLRTPEGNISAIDRYEQHLKNKTGENIDLYIT
                     EVGYPTNSSKGGVEPELAAQYMVKYTFLAKQRDYIKGIWWYTLMNSADNTSNRESNFG
                     ILMHNESEKPSAKCLKQNEQLIAGALTNQKNASSSISCSGQ"
     gene            21647..23053
                     /gene="gnd"
     CDS             21647..23053
                     /gene="gnd"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate-6-phosphate dehydrogenase"
                     /protein_id="BAT24276.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA
                     ENPGKKLVPHYTVQEFVESLETPRRILLMVKAGAGTDSAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILKQIA
                     ALAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLALSNEELAQT
                     FTEWNEGELSSYLIDITKDIFTKKDEEGTYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLTGPQAKTADNKAEFVEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYHWDLNYGEIAKIFRAGCIIRAQFLQKITDAYEQNAGIANLLLAPY
                     FTQIADDYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRTDKEGIFHTEWLD"
     CDS             23432..24433
                     /note="HG209; orf18"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="BAT24277.1"
                     /translation="MKYLVTGAAGFIGFHISQRLLKDGHQVTGIDNLNDYYDVNLKQA
                     RLDLLQSPLFSFHKIDLADRAKMEQLFFSEKFDRVIHLAAQAGVRYSLENPHAYADSN
                     LLGFLNILEGCRHNKVKHLVYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANEL
                     MAHTYSHLYGIPTTGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFT
                     YIDDIVEAIIRLQNVLPNEDSEWSVESGSPATSSAPYRVYNIGNSSPVELMDYITALE
                     EALGMIAEKNMMPMQPGDVMETSADTAALYNTIDFKPETSVKKGVGSFVDWYKKYYQ"
BASE COUNT     7721 a   4516 c   5679 g   7914 t
ORIGIN
        1 tatgggtggc gatggaagga taagtagggt gcatcacggt gagcgcgcat tgtgatccaa
       61 cgaaataaat ggcataagaa ttttcttaaa tcggcctgtc ggccatcgta ctttaagtgt
      121 attctctggt taaacgcgta aattcagaat ttgacgggaa gtcgggccgg tcgcaaacct
      181 gtattatcag caataaatgc cgttgataca tgcggtctga caggcataga aagatctata
      241 acttacggat ggatatgaga atggcgaatt tgaaagcggt tattccggta gcagggttag
      301 gtatgcatat gttaccggca actaaggcga tccccaaaga gatgctgccg atcgtcgata
      361 aacctatggt tcagtacatc gttgacgaaa ttgttgccgc cggcatcaag gaaattgtgc
      421 tggttaccca ttcatccaag aatgcagttg aaaaccattt tgatacctcc tacgagctgg
      481 aagcgctgct tgaacagcgc gtgaaacgcc agctgcttgc cgaagtgcag gctatttgtc
      541 cgccgggcgt caccattatg aacgtacgtc agggacagca gcttggttta ggccactcta
      601 tcctttgtgc gcgcccgatt gttggcgata acccgtttgt tgtcgtgctg ccggatatcg
      661 tattagacga tgccagcgcc gatccgctgc gctacaacct tgcggcgatg gttgcccgct
      721 ttaatgaaac ggggcgcagc caggttctgg cgaagagaat gcccggcgat ctggccgagt
      781 attctgttat tcagacccgt gaaccgctgg aaacagaagg gcagatcggc cgcattgtcg
      841 agtttatcga gaagccggat gagccgcaga ctctcgactc cgacctgatg gccgtaggcc
      901 gttacgttct ttccgccgac gtgtggagtg aactggagcg cgctgagccg ggcgcatggg
      961 gccgtattca gttaacggat gccatcgcag agctggcgaa aaagcagtcc gtcgacgcta
     1021 tgctgatgac cggcgagagc tacgattgtg gtaagaagat gggctatatg caggcattcg
     1081 ttaattacgg actgcgtaac cataaagaag gcaacaaatt ccgcgagagc attaagaagc
     1141 tgctggccta acagcgtaaa aatagcgggc tacggaagca aaattaagaa ggtaaatccc
     1201 tcgatgcttc tgtagccggt tagatagcct ttagcctgaa aaaaatattt atctaaaaaa
     1261 catatacaat caatgggtta gagattttag ataagcattt cactgaattt atgcgaaata
     1321 agccctgtgg aacaggttgc gagcggataa cggcaaaact gcgtaatggt cagacgagca
     1381 gaatttaatc ttaatgaaga actacttagt aagattattc ttaaaacaga tgcgtagtcc
     1441 cggcgaacat aaaaaaataa aacttgactg agatcatact tacgcattaa acaacggtta
     1501 tgcatgcata aaaatgtgaa gtttatgggt atgcatgccc acataaacat cgtggaaaaa
     1561 cgctatgaac aggagatatc gtcaaaggat gaaaagtaaa tgagctggca atttgtctcc
     1621 ttttttggcg atagcaccgt gctgttacct agcgcggcgg tactgttgat tgtgttgttc
     1681 ctgcgggcac catcccggca ggtggcctgt cactgggcac tcttgttcgg tatcactggc
     1741 gcaatcgtta gcgcatctaa actggccttt atgggctggg gcatcggaat tcgggaactt
     1801 gactttaccg gttttagcgg acataccgct ctgtcagccg cattttggcc gatattctta
     1861 tggcttcttt tctctcgcgc tacgacagga gtgcgtcgcg ccgccgtcgt agtgggctat
     1921 gcccttgcgg cgctggtggg ttactccaga ttaatgattc acgcccactc cacctcggaa
     1981 gtggtcgcag gcctgctgct tggtgcgagc ggcagcgcat tgttcctcct gctgcaatcg
     2041 cggatatcgc gggcggagaa tgtacagctt tcgtggagcg gggtgttcag cgtaatgatg
     2101 atccccgtcc tgctgcttaa cactggcgta aaggcgccaa cccagtcctt actgggtgag
     2161 attgcggtga agattggccc gctggaaaag ccctttaccc gcgcggatct gcataagcac
     2221 ttttattgat tacgccaaag acaggcgttg agcttgcggg catcgcgcaa tatcccggac
     2281 atagcgctag catcaggata gctgcagatt gattaagtgg actaaagcgg cttcatattc
     2341 gtgaaataaa taactgctac tacatcctgt gcaatatcca tgatttttat aatgcttgtg
     2401 agatgattcc taaatagaac gataagatta acgtctgatt ttaaattatg tttgtcaagt
     2461 ataatcatca aactaaatct attagatttt gtagttgacc ggagcggata gtgaatgaat
     2521 taattcgtat tggtggctgg ttaaattcat taaaaacaat gagttaaatg atttcgtcta
     2581 ctgcgatgag tgttaagact acaaatttta cgacactgct taataagctt aatgctaagc
     2641 atgtgcatgg ttttagcgtc aagcttgatg ggttttaatg agtgaataat tttcatttgc
     2701 tctcccattt gacggcagaa tctcgtaaac ttgatgccgc taaaattata gttagtgatt
     2761 agttattcga cggacatgaa gtcggtcatt tggcttaaaa aggaagtaca gtgcattggt
     2821 agctgttaag ccaagggcgg tagcgtttcc gaaagtactc gaatcctttc agcaaggcct
     2881 tcttcaggcg ttcgaaattc ctaaaacctg tctcggcagg tgaataacct gacggcccgt
     2941 atatactgag tcgctttcag agaatagcca gtgcgatctg cagcaacgtg ccagccaagg
     3001 caaaacccag caaagaatag ttcttgataa cgctacgcgc gttttttgct tgcattatat
     3061 gcgatatgaa cgattatcaa ccgctgaggc ggcgacgttt caccgatgat tcactctatc
     3121 gctccccggt gaccgttgct gcagtataga tgtgacacaa acatactgaa ggctggcgtc
     3181 agagtacgct ctcaatacct acattccccg caactatgtc tgtttgccgg tggggctaaa
     3241 aaaatggatc ttgcataatg atgaaaattg cgcgtatcgc acttgctctc gggctgctta
     3301 cctcggtgag ctcgccggtt tttgccgctg gtctggtgac gaatgataac gagctgcgta
     3361 acgacctgtc gtggctatcc gaccggggcg ttatccagct tagcctttca acatggcctc
     3421 tgagtcagga agagattacc cgcgcattga agaaggcaaa gccctcctat tcgtcagagc
     3481 aggttgtcct ggcgcgcatt aacgaacgcc tctcttccct gaaagctgat ttccgcgtca
     3541 gcggctatac ctcgacagat cagcccggaa cgccgcaggg ctttggccaa agccagcccg
     3601 cggataactc gctctcgttg gccttcaata atagcggcga atggtgggac gttcatctcc
     3661 agggaaatgt tgaaggcgga gagcgtatca gcaacggctc tcgctttaat gcgaatggtg
     3721 cctatggcgc cgtgaagttc tggaaccagt ggctgtcgtt tggccaggtg cagcagtggt
     3781 ggggccctgg ttatgaaggc agcctgatcc gcggcgacgc cgcaaggccg atgaccggct
     3841 ttttaatgca gcgtgccgag caggccgcac cggaaacctg gtggctgcgc tggattggcc
     3901 catggcagta tcagatctcc gccagccaga tgaatcaata taccgcagtg ccgcatacca
     3961 agattatcgg cggccgatta accttcactc cgttccagtc gcttgaactg ggtgcgtcac
     4021 gcattatgca gtggggtggg gaagggcggc cggaatcgtt tagtaatttc tgggatggcc
     4081 tgacgggtaa agataacacc gtatcaaacg atcccaatga gcctggcaac cagctagccg
     4141 gttttgactt taggttaaaa ctggaaccta cgttaggtct gcctattagt ctatacggtc
     4201 aaatgattgg tgaagatgaa tctgggtatt taccttcagc aaatatgttc cttgggggag
     4261 tcgaaggaca ccacggttgg ggtaaagatg ccatcaactg gtattttgaa gcccacgata
     4321 cgcgttcgaa tatgagccga actaattata gttatacgca ccatatatat aaagatggat
     4381 actaccagca aggctatcca ctcggcgatg caatgggagg cgatggtcaa ctctttgctg
     4441 gtaaagtcga actcgtgaca gaggataatc aacgctggag cacacgtctg gtctatgcaa
     4501 aagtaaatcc aaagaatcag tcgattaaca aagcctttcc ctattcagat actttaaagg
     4561 ggatccaact aggctggagc ggtgatgttt atgagacagt tcgcttgaat acaaatattt
     4621 ggtacaccga tgcagataat agtgatagtg atgatatagg tgccagtgca aaaattgaga
     4681 ttccgtttag tttttagact ggatactgag aaatgcagat gcgatgctga tgtgagagat
     4741 gttgcagtca aattgtgggg tgatggtaat aactgcagct caaaaattgg caaattttgg
     4801 tttattgatg atgtgacatt atgaagaaaa atattgttag ggtttcagca gtggcattgg
     4861 ctattagctt tttaacaggt tgtactattg ttcctgggca agggttaaat agtttacgca
     4921 aagaggtggt tgagttaccg gatagtgatt acgatattga caagttagtc aacgtctatc
     4981 cgatgactcc tggtttgatt gatcaattac gtccagataa tgtggttgct cgaccaaatc
     5041 cacagcttga tagtttatta caaaactatg aataccggat cggtgttggc gatgtactta
     5101 tggtaactgt atgggatcat ccggaattaa cgactccggc aggtcagtat cgtagtgcca
     5161 gcgatacagg taactgggtg aattcggatg ggacaatgtt ctatccttat attggtaagg
     5221 tgaaagtagc gggtaaaaca ttgagccaag tgcgacaaga gattactagc cgattaacaa
     5281 catatattga aagtccacag gttgatgtca gtattgcagc ctttaggtcg caaaagacct
     5341 atgtaactgg tgaggtaatt aaatccgggc agcagcctat cactaacatt ccactgacag
     5401 tgatggacgc aatcaatgct gccgggggat tagcaactga tgctgattgg cgcaatgtaa
     5461 ttcttactca taacggtaaa gatactaaat tatcattata tgctttaatg caaaaaggcg
     5521 atctaactca gaatcacctc ctatatcctg gagatattct atttgtacca cgcaacgatg
     5581 atcttaaagt ctttgtgatg ggggaagtgg gcaagcagag taccatgaaa atggatcgta
     5641 gcggtatgac acttgcggag gctttaggca atgcagaagg catgtcgcag tcactgagtg
     5701 atgccaccgg ggtctttgtc attcggcaat tgaaaggcga taagcaaggt aaaattgcta
     5761 atatttatca gctaaatgct caagatgctt cttcaatggt gcttggtact gaattccagt
     5821 tacaaccata tgatattgtt tatgtgactg ctgctccact ggtacgttgg aatcgtgtga
     5881 tttccaatct agtaccgacg atcacaggcg tgcatgattt gactgaaacc gttagatata
     5941 tcagaacttg gccataatta tgtttaattc aattcttgtt atttgcacag gaaatatttg
     6001 ccgctctcct ttaggggagc gatatttgcg taaaatgtta ccgggcaagc gaatagactc
     6061 tgcaggtaca ggtgctcttg ttggtcatgc tgcagatgag tcagcatcaa agatcgccgc
     6121 cttgaatggt ctgtctttgg atggacatca gggccggcaa ctcattccat cagttgcacg
     6181 agaatatgat ttgatattag caatggaaaa agtgcattta gaatatgtca gccgaatcgc
     6241 acctgaagtt cgtggtaaaa ctatgctatt tgggcactgg ttaggtcaaa gggagattcc
     6301 tgatccttac cggaagagtg aagaggcttt tgtctcagtt tattccttaa tcgaacaggc
     6361 cggtaaaaat tgggctgaaa aactgggctc ataattatta ggaacttatg catgtcatca
     6421 gcaaaaaata aaacagcagt caaagatcca gatgaaatcg acttaggacg tctcattgga
     6481 gagttaatcg atcaccgtaa attaatcgtt tcagtaacat cattatttac gctattagca
     6541 ttagtctacg cgttgtttgc tacgccaatt tatcaagcgg atgcattggt acaagttgag
     6601 caaaaacagg gtaatgccct attaaatagt ttgagccaaa tattacctga tagccagcct
     6661 cagtcagctt ccgaaattgc attattaaga tcccgtatga ttctagggaa aacagttgat
     6721 gacttaaatt tacaggcaaa aattgaggaa aattatttcc cagtatttgg caggggatta
     6781 gctcgactac ttggttacaa gccaaataat ttaaaaatct cacgcttata cctcaacatt
     6841 cccggggaag atgttcctga aattgaaatt aaagttttag ataataaaaa gtttagtata
     6901 acaggtgacg gtattgaatt aactggaact gtaggcgaac ttgtcgaagc gaaaggtttg
     6961 tcattgctgg tatcagaaat tggtgcagaa ccgggaacca cgtttactgt ttcttatatt
     7021 cctcgtctga aggctataac taatctgcag gataatttgg cgattgttga tgaaggtaaa
     7081 gatacaggca ttttaacgtt atcacttact ggtgacgatc aagcgcaaat caagaatatc
     7141 atcgatggga tcagtactaa ttatctggcg cagaatattg ccagacaggc tgcgcaagat
     7201 gcaaaaagtt tagaatttct gagtgagcag cttccaaagg ttcgtagcga actagattta
     7261 gctgaagata aattgaatgg ttatcgtcag caaaaagact cagtcgatct gtctctagaa
     7321 gctaaagctg tacttgacca aattgttaat gttgataatc aattgaacga attaacaatc
     7381 agagaatcag aagtttcaca gttattcact aaagaacacc cgacatataa agcattgatg
     7441 gaaaaacgta agattcttca ggaggagaaa agtaagctaa ataaacgcgt atcagcaatg
     7501 ccagaaacgc agcaagaagt tttacgtctc agccgtgatg tagattcggg gcgggtagta
     7561 tatatgcaac tcttgaatag acagcaagaa ttaagtattg cgaaatctag tgcgataggt
     7621 aatgtccgaa ttatcgatac tgcaataacg caacctaagc cagtaaaacc aaataaagtg
     7681 ttggttactt tgttaggttt aattattgga ctgcttgtat ccgtaggttt agttcttgcc
     7741 cgtgttgtat tacgtaaagg cattgaatcc ccagagcaac tggaagagtt gggcataagc
     7801 gtatatgcaa gtgtacctat atcagaggaa tttgcgaaac gtgtagaacg taccaacaaa
     7861 atcaaaagta gaaagcctga tgaagttgct gtctttttag ccgttgaaaa tccagcagat
     7921 ttagctatcg aatctattcg agggctacgt acgagcttac actttgcaat gatggaagct
     7981 aggaacaatg ttttaatgat caccggcgct agtccaaacg caggtaaaac attcatcagc
     8041 tcaaaccttg ctgaggtgat ctcacagact ggtaagaaag tgcttttcat cgatgccgat
     8101 ttacggaaag gatacacgca taaattattc aacatcgata ataataatgg tttatccgac
     8161 atactgtctg gcaaaacaac aatggatctt gcggttaaaa atatacctaa tattggtttt
     8221 gattttattt ctcgaggtat ggtaccacca aatccagcgg agttacttat gcataaacga
     8281 tttggtgaac ttatcgattg ggcaaatagt cgttatgatt tagttatcgt cgatactcca
     8341 cctattctag ctgtaacaga tgctgcagtt atcgggaact atgcagggac aacgctatta
     8401 gttgctcgtt ttgaacaaaa tacggctaaa gagattgagg ttagtattaa acgatttgag
     8461 caaagcggtg tgaacattaa aggttgcata ctgaatggtg tagttaaaaa agcgagtaac
     8521 tattatgggt acggttataa ccactacggc tatacatata ctgataaata acttctgact
     8581 taaacttgac taaccgaggt taatgtgcct cggtttttct atgcagaaaa aattatctac
     8641 gctcatatta taaacagaac aacaagagtc tattgtgagg aagttatgag acttattgtt
     8701 aaaaatgctt tggttagtac aacgcttgcc ttatctgact tcttaggttt tatcatttcg
     8761 ccctatctgg cgatactttt tttatcagtg gtgttgaata attatcaaga ggtggtacct
     8821 ccgcgagata ttgaaagttg gttaggtttg cattggttac tgggtttttg ttgcgttgca
     8881 tggtattcag ttcgtttgcg ccattatttc tatagaaaga cgttctggtt tgaacttaaa
     8941 gaaatcttaa gaactctggc aatatttgct gttatagaaa ttgctgttat ggcttttaca
     9001 acttggtcat tctcgagata tcttttggtg atatcctgga tgttgatatt agtcttggta
     9061 ccattattcc gaatggtggc taagaagtta ttaaatatgt ctgggttgtg gatgcgagat
     9121 acctggatta ttggtaatgg aaataatgca tatgaagcat acaaggccat aaccagcgaa
     9181 cataatttag gattgagaat agtcggtttt gtagaagtat caaaacctat ggtttcgcaa
     9241 aaaactgttt ttggtgttcc aataattcat gcgagtgccg attggttaaa tactattgat
     9301 aaaaaaaatc agtttatagt cgctgttgaa tccacagaga gtgaggaaag aaacatgtgg
     9361 ctacgaaact tcatgattaa gggttatcga tatgtttcag taattcctac actaagaggc
     9421 atgccattag atagcactga tatgtctttt atttttagcc atgaagtgat gatctttcgt
     9481 gtacagcaga atttggcaaa gtggtcttct cgcttaagca agaggctatt tgatatagta
     9541 ggttctttat caataatcat cgttctttca cctctgctta tatacattag tagaaaagtt
     9601 aaaaaagatg gtggtccatc tatctatggc catgagcgaa taggtaaagg gggtaagccg
     9661 ttcaaatgct taaaattcag atctatggtt attaattcta aagaggttct tgaccagcta
     9721 ttgaataatg atcttgaagc aaaagaagaa tgggataaga catttaagtt aaaaaatgac
     9781 cctcgaataa ctaaaattgg tcatttttta aggagaacaa gtcttgatga attgcctcag
     9841 ctatttaacg ttctcaaagg ggaaatgagc cttgttggtc caagaccaat aattacagct
     9901 gaactagaac gttataatga tgaggttgat tattatttac ttagtaaacc tggaatgacg
     9961 ggattatggc aggttagcgg tcgcagtgat gttgactatg agacccgggt atatcttgat
    10021 gcttggtatg taaagaactg gtcaatgtgg aatgatattg cgatattgtt taaaacaatt
    10081 ggcgttgttt tgaaaaaaga tggtgcatac tagtaattat cttcgtaact ccttccatta
    10141 gaggatatac gctctaaaag atcttaaggc tgaatgtgat gacttcatca ttaaagaaaa
    10201 ctgcggttag tgggctaatc tggagcgcaa tcgagagatt ttcagtccaa ggtacgcagt
    10261 ttatcgttac aattatcttg gcaaggttga tatcacctga agattttggt ctcataggga
    10321 tgataacagt atttattgca ttgtctgatc tgattattaa cggcggattc tctcaggcac
    10381 taattcaaaa gaaacaaaga acacaagatg atttttctac agttttttat tttaatatta
    10441 taatagctgt gttcatttat ggtttgatat actattttgc tccgtacgtt gctaaatttt
    10501 ataatcaaat gccattgatc gatattctaa gaattcttgc gatatcagtt gtattgaaat
    10561 cattttgtgt tgttcaaaat gccattctat caataaaatt gaattttaaa ttaaggacca
    10621 agattaacct tataagtgcg cttctcagtg ggattcttgc aatttatatg gcatataagg
    10681 gattaggtgt ttatgcatta atttaccaga ctattatttt ttcgctttta gtatctgtat
    10741 tctcttttgc actgattaga tggttcccat cattaatatt ttcttatgat tctctgaaag
    10801 tactttttaa ttttgggtcc aaactacttt ttgctagcgt ggttagaaca attgtagata
    10861 actgctatgc gattttgatt ggtcgtttcc tgtctataag ggatgtagga tattatactc
    10921 agggaagaaa tatgcctgat gtattatcta tgaatttgta caatgtttta cagaacgtat
    10981 tcttcccgtt aatgtcagca catcaggatg ataaagaacg tttattgaaa atatataaaa
    11041 agggaattca gggcactgca ttcattataa taccagcgat ggttgggttg atgcttatag
    11101 cggacccatt tgttcactgt gtgttatcag ataaatggaa gggggcaatc attgttattc
    11161 agtgggttgc actctctcgt attataatac caattagcgc tcttaattgc agtattatta
    11221 atgcggtcgg aagatcagat atctatttaa aaatagattt gctcaaatta ccacttacga
    11281 ttggtgcttt attggcaact ttctcttttg gcctggaggt tatagtaatt ggtaatgtat
    11341 tagtttctgc catatgcttt tttattaatg cctattatcc aggtaaatgg ttcggttttg
    11401 gagcttggga acagttaaaa aaaatatcac cagttatttt ttgtacatta tgtatggcat
    11461 tgccattgta tttcattaaa cttgataata aattactgga aatgattctc aaactaggta
    11521 tagggccgat catatacagt atcatgtgtt atctgctgaa agttgagact tttatggaaa
    11581 tgtgtacatt attgaagagt aaaattaaaa aggaatcagc atgaagaagg ttttagcaat
    11641 taatgaatgc tgttcggata atattggtga tcatgcaata aatcatggtc tacaaaaact
    11701 aataatgatt aactcttatg aggctcaatc tgtcggtttt gatgctggtg taaaacatga
    11761 gaaacctcaa aagatcgcta ctgataatgt gcatttatca tttagaacac gattcaaaaa
    11821 aaaatatttg agcggaagac agagtttaaa atatgcatta tggttaataa aaaatttact
    11881 gagagttcgt tctactgtaa aaaatgaaca tcaagccgca attatcggtg gtggacagtt
    11941 gatacaatct ggcggaacat ttcctatagc aatgtttgtt tggacttttt actgtaaaaa
    12001 gaaaaatctg ccaatttata ttgctggcgt gggatgtgct gaaaaatttt caaaactcga
    12061 cgtttggcta tacaaagttt cttttaagcg tgccaaaaaa atttttgtta gagatgtttc
    12121 atctcgtgat aaactaaaaa gtatcttttc tacagaatct gaactaatac ccgatttagc
    12181 ctatgcacta tatgatgaag gaacattctt ttcagataag aaggagcgaa cattaattgg
    12241 ctgcacctct tattatgtat atgaaaaaaa catcaaagaa ttatcgcgaa aagacgggct
    12301 aacaaattcg caatatatcg ataagtggca aagcatagtt ctttctgaac ttaataataa
    12361 aaaagaagtt atcttagcat ctacaaccgt tcaggatgct gtacttaata aattgattta
    12421 tggaagactt gttgaacttg gttactcatc aaagattgag cttgttgaaa gtataccgtc
    12481 aacatacgaa tacttggctt tattaaataa cgttaataaa gtcatctcgg gaagaatgca
    12541 tagtttaata cttggccata tctcaggatg taggatagag actatcgaca taaataagaa
    12601 gattgatcag tttatgtttg aatattcgga taaacatcct tccgaactaa atgctaacct
    12661 taacgaaaaa ttcaaaaata taatttaacc cacaatgaat gaagattaaa cttgggagat
    12721 ccttttggaa agagtaataa tatttaccaa tgagttttat ccttttaaag gtggcattgg
    12781 tcgttattgt gaggaattaa tcattgaaac aattaaaaat ttccaagtca ctttggttgc
    12841 cccaaaatac gatggagatt ttttgaataa tgatttagca aaacatattt cgattgattt
    12901 tttagaaggt ggacagttta agtattggca tttcccaaag ttaataaaaa aagttttatc
    12961 tatagacttc actctttacg atcatgtatt ggttgctgat tggccttttt gggtggctat
    13021 tgaatttgta aataaatatt ttccatggaa agcaaaaatt agatattccc ttatgctaca
    13081 tggtagtgag gttttaaatt taaaaaatgg tcgcgcatcg atttttccta agattataga
    13141 tatatttggt gggacaaaaa atatttacac aaacagtaat tatacaaaaa atatattgca
    13201 tgaaaatcac aacgtgcctt ctactattcc cgtcgaggta acatacttag gcgtttctca
    13261 aactgaaaac ctttctaatg aaaattatat tgctaacgtc aaaagtgaga gattccagtt
    13321 gttatcggtt ggacgccttg atgatagaaa aggatttgac aatgttatta aagcaatagg
    13381 tttattggac gaagctgtaa aatcaaaaat atattttact atcgttggaa acggtagtga
    13441 tgagtataaa gaaattttga atgatttagc aaagcaaaat aaagttaatc taaatatatt
    13501 gtcgggtctc aatgataatg aattaaatga atgctataac agaacgaatc tttttatttt
    13561 agctgcacgt aacaataata aaaaaataga aggttttggc cttgtttttc tagaggctgc
    13621 taaattcgga gtgccctcga tagcaacgga cgtgggggcg attaaagaag tagttaaaaa
    13681 taataaaact ggattcgttg taaaagagga tatccatgag ttaatgaaag ctatatacaa
    13741 ttgttatatc gatcgggata tattgattga gtttagtaga aactgcatca ctaatgtgca
    13801 agaatttaaa tggtcgacgc tggcaaataa aaccttcccc aaaattatgg ttcaaaaaaa
    13861 tgaaaaatat taatatattg tatgtagata cctgtttgga cgttgctggt ggtcagcgct
    13921 cattaattgc attattaacg aatattgcaa gtcagataaa tttttcaata cttattgatg
    13981 aagctaataa aaaatatgag caggaacttt taaaggctgg tatatctaat aatgctatta
    14041 tcaagataaa gacttgcacg gttggtgggc gcgctttggg tgggcttatg ttattcaatt
    14101 ctgtattacg taaggcggcg aagtttgata tcatacactg taatactttc tatgatggtc
    14161 tttttgcgat gccagctgca agacttcgag gaaaaaaaac aattttccgc gctagatgtg
    14221 ggatagattt gtctaatcat ggatatattg ataatgtaat ttataatttc tcgacaagaa
    14281 tactggcgaa ctctgattat gttaaaaata cgtttagacg tgtatcatca gatttaaata
    14341 aagttatctc tttatataat cccttagata tgaaatttca taaggagatt aatccagatg
    14401 ttataaattt taaacatgat gttcaaaaaa attatgttat agcagttgtt ggtgctatta
    14461 cagaagttaa aaatcaaatg gaagtactta aagccctcgc tcagcttaag gatacatcaa
    14521 ttaaactaag atttattggt gagccaagaa gtactgagaa agatagaaaa tactataatg
    14581 acctattaaa ttatgcaaaa gaaaataatc tattgcctca agtcgaattt actggttttg
    14641 tctcagatgt tagagataaa ttaggtgacg ttaatttagt ttgtgtgcca tcagatagag
    14701 agccgcttgg tcgtgtaatc tttgaaagtc aactattcgg aattccagtg ttagcgtctg
    14761 attcaggagg taactctgaa ctcattgaag atggttcgac tggttattta tacgcgttgg
    14821 gtaatgtgaa cgaactggca actaagcttt taaaagtaaa agataacaac catcaacttg
    14881 ctttagatgc tcaacgattt gtattaaaaa gattttctcc agagcggaca tatctcgaag
    14941 agcttaatct ttatcatgca ataaaataaa ctattttaat taactataat tggggtttat
    15001 ttcatttggt ttataagaaa ggctagatga tacttataaa ttgatccatt ttgtaaggct
    15061 tagtaagggt agagcatggc tctttctatc aagaaattaa acttaaatta tgcactaata
    15121 attgctttta ttgtgattat cttacctcaa gtaatcttga aaccaatagg tggcgattta
    15181 tctattgtag atattggggc tcctttaata attgcctact gcatgtttcg ttatcaacta
    15241 aggttgcctc caccacaaaa atacctattg gtttttatat tttacttgtt ggtatcttat
    15301 ttagtaatga tgctatttgg tgggattgaa tatcaggaat ccagccctta tttaatcagg
    15361 atggtgtctt tatatgcacc aatttttttg gttccatact taggaaatga tgagacacag
    15421 ttcgttaaat ttggaagggt gttcgtagta atatctttaa tagcaactgt tgccattatt
    15481 tttctgtata tttccgggtg gacaggagtt agtgctcatc aaactacgga aagcgatgat
    15541 ggtttaaagg tcaatagatt aggggggcta cctggagaat caggcgcatt tgcctacaac
    15601 attttattcg tattctacat gtctcttatt gtgtatctag ttgcagctaa aaagtggtta
    15661 attaaaatag tgagttttgg tttgacgctt gttgtgctat ttttatcgtt caagtatagc
    15721 ctagcacgcg taattgttat ttgtgcgggt gcggttatcg tatgtggata tttcttcaca
    15781 tcaatgtctc taataaaaaa atactttcta tttttaatga cttttttgat atgtagtagc
    15841 gctatttttt ttgtttcacc tgactcactc gacttatcga aatatagatt atcaaacgtt
    15901 gcaagtactg atatgaactc ggtctcgtca gggcgtgtgt cacactggat agatgcagtt
    15961 acattatatg tagaaagtcc ctttcatgtt atatttggtg ttggacatcg catgtcagta
    16021 cgttttcttg gacatgccgt agaaaacttt tttattcaaa atcttcttga ttatggtatt
    16081 gttgggacta tccttttcat catgtttcta tgggttctac ttaaacctat tataaaagat
    16141 tcgagagcaa ataatagtat ttcagttgct gttttattag tattcactgg tattttcttg
    16201 caatggcaat tcaatgacat caacacctac tatcaaacat atccagctac gttattcttc
    16261 ctgagttggt ggagtcaaat ttgtcgtaaa cggaatgtta cggacgagaa tggttgaatt
    16321 agtattatat ttaaaactta ccaaggtggt gaaataatga ttactccagt tattatggca
    16381 ggcggtaccg gtagccgctt atggccgatg tctagagaat tataccccaa acaatttctg
    16441 aagttatgtg gttcgaactc gatgcttcaa gaaaccattg tcaggctgga tgggcttgat
    16501 gtaagcaatc cagtgctaat ttgcaatgag cagcataggt ttttggccgc agagcaacta
    16561 aggcaaattg actgtttatc tggcgatatt attcttgagc ctgtaggaag aaatacagca
    16621 ccagcaatag ctttagctgc tctgcaagcc atttcagggg gtaaagatgc gttacttctt
    16681 attttagcgg cagatcatat tattgatgat atttcttcct tccatgaagc tgtaaataaa
    16741 gctattcctc atgctaaaga tggccggttg gtcacttttg gaattgtacc ttctgggccg
    16801 gaaacaggtt acggttatat acaaagaggc tctgccgtac agaatcatga gcaagcttat
    16861 aaagtccagc gatttgttga aaaacctgat ttaaaaacag ctaatgatta tgttataagt
    16921 ggcgagtatt actggaatag cggtatgttt ttatttagcg ctaaaaagta cctagatgaa
    16981 cttgcaaaat atcgtcctga tatttcaaat gcctgtgaaa aatctttttc ggtagttgaa
    17041 aaagattcta tgcaagattt tattcgtgtt gatgctgaaa aattcaaact ttgcccggat
    17101 gaatccatag actatgcggt gatggagaaa actgaggatg ctgttgtgat acctttagat
    17161 gccggctgga acgatgtcgg gtcatggtct gctctctggg atgtgaacac caagaataat
    17221 gataataatg cattaattgg agatgttttt acatataatg caagagattg ttatattaat
    17281 acagatgaga agtttgttgc tgcaataggt gttgaaaact tggtaattgt taatacaaag
    17341 gatgcgacct tagttattaa taaagataaa gtccaagatg ttaaaaaagt tgttgagttt
    17401 ttgaaacaag ataatcggcg ggaatataaa atccatcgtg aatcatatcg gccatggggg
    17461 gtacaggata aagttgttga tactgctcgc tatcacgtta acaaagtaac tgttaaaccg
    17521 ggcggcaaat tttcgctaca aaagcacatt catcgagctg agcactgggt ggttttatca
    17581 ggaactgctg aagttaccct tggtgaacaa acttatttgt taactgaaaa ccaatcaacg
    17641 tttatccctg ttgggcaaac tcatatgtta cataacccag ggaaaatacc tcttgtcatt
    17701 cttgaaatag tctcgggtac ttatttgggg gatgatgata ttatccgttt gaaagaccat
    17761 tatggccatt tttgaataag gcaatactta aatgacaaat aaactatctt gcttcaaggc
    17821 atatgatatt cgcgggaaac tcggtgacga attaaatgaa gatatcgctt atcgtattgg
    17881 tcgcgcatac ggtgagtatt taaaacctaa ggaaattgtc cttggggggg atgtccgtct
    17941 gaccagcgaa agtctcaagc ttgccttggc taatggatta caggatgctg gagttgatgt
    18001 catcgatatt ggtcttacag ggaccgaaga aatttatttt gctactagtt atttggcgat
    18061 tgatggaggt atagaagtta ctgctagtca caaccccatg gactataacg ggatgaagct
    18121 agtcaaagag aactctaagc caattagcgg tgatactggc cttcgccata tccaaaagct
    18181 cgctgaagaa aacgcttttc ctactgtgtc tgctaatagt cgcggtagtt ataaaacgat
    18241 gtcgatttta gaaccataca tcgataaact tttgtcttat gttgaattat ctaatttctc
    18301 gaagcctctt aagttagtgc ttaactccgg caatggcgca gctggtcatg ttattgatgc
    18361 aatagaagaa cgatttagat ataataattt acctattgat attgtaaaaa ttcataataa
    18421 tcctgatggc cattttccta atggtattcc aaatcctttg ttgcctgaat gtaggcagga
    18481 taccatagat gctgtcattg cacataaagc tgatctaggg attgcatttg acggtgattt
    18541 tgatagatgc tttctttttg acgaaaaagg taatttcatc gaagggtatt atattgttgg
    18601 gcttttagcc caagcatttc tggaaaaaga acctggttca aagattatcc atgatcctcg
    18661 acttagttgg aatacaatcg atttggtctc agagtctggt ggtatacctg ttatgtctaa
    18721 aactggtcac gcttttatta aagaaagaat gcgacttgaa gacgcaatct atggcgggga
    18781 gatgagtgct catcattatt ttcgtgattt tgcttactgc gacagtggca tgatcccttg
    18841 gttattagta gcagagttaa tttgtaacaa aaatcagagt ttgaaccagc tggttagcga
    18901 tagaatgaag gcatatccag catctggtga aattaatagt tcacttgcag atccaaaagc
    18961 ggccattgaa cgtgtattgg aaaaatataa agctgacgct gtatgtattg accatactga
    19021 tggtataagc ctcgagtatc ctaattggcg gttcaatcta cgcagctcta atactgaacc
    19081 ggtggtacgt ttgaatgttg agtcaagagg taatcgggat ttaatggttg agaaaaccaa
    19141 tgagattctg gcacttttga gatcttaatt ctttatagca agcagataga ctctgcttgc
    19201 tttcttttat cgattatctt tacagtttag gtgttaaaat gtcgggtgag attaatatcg
    19261 gtattgtagc tgattggcta gttacatatg caggttctga aaaggttatt aaagaattta
    19321 tcgatgtatt cccttcagca gaattatatt cggtagtaga tttcttatca gattcgaata
    19381 gagcattatt tgcggggaag aatgcacata cgacctttat tcaaaaaatg cctttcgcaa
    19441 aatccaaata ccagaaatat ttacctttga tgcctttggc tatcgagcaa ttggatatgt
    19501 ctgggtatga tgtgatttta tcaagtagcc atgctgttgc caaaggtgtt ctaacggggc
    19561 cggatcaatt acatattagt tacgtccatt cgccaatacg gtatgcgtgg gatcttcaac
    19621 accaatattt acgagagtct ggtctgtcta acggattaaa aggtcttatt gcaaagtatt
    19681 tattgcataa aatcagactt tgggattatc gcacagcaaa cggtgttgat cactttatag
    19741 ctaattctaa attcatttcc agacgtatcc ataaagttta tggccgctca tcagatgtta
    19801 tatatccacc tgttgatgta aaaaatttca aactaaatga aaataaagaa gactattatt
    19861 ttactgcatc aagacttgtg ccttataaaa gaatcgatct gattgttgat gctttcaatg
    19921 agatgccgga taaaaagtta gttgtaatag gcgatgggtc tgaaatgcat aagatcaaat
    19981 ccaaagctaa aaagaacatt gaaatcttag gctatcaacc aaacaatata atgcaagagc
    20041 atatgcaaaa tgctaaagct tttgtttttg ccgcagaaga ggattttggt ataactcctg
    20101 tggaggctca ggcatgcgga acaccggtca ttgcttttgg taaaggaggt gtcctagaaa
    20161 ccatcaattc gattgaaaat acacagccaa ctggactttt ctttgataag cagaatcctc
    20221 agtgtattat tgaaagcgta aagaaattcg aaagtatgca agatgttttt gagcctattg
    20281 aatgcagacg caatgcagaa aaattttcag aggaaagatt tagaagtgaa atcaatgcat
    20341 atgttcgcga taagtgggct atgttcaata attgctaagt agcaacagat ttcattaatt
    20401 catcaacaat gcaatcctgt tttaaacttt tagattgtga gggctacatt atggcaacat
    20461 cattaagtaa aaaagttcgt taccttttgt tacttttgac cttatgccat atgactgctg
    20521 tttgtgcatt tgagtttggt attggaactc atatagcaaa ttacaaggaa agttctgagt
    20581 tttatataca aaaagtcaag tcgtatggtt ttaactcagt gcgggatgag ctttattgga
    20641 atgatgttga gaaacaaaac ggagtcttta gcattccgcc caatcgtact aaaacggatc
    20701 attattttca aaacctacaa tctaacaatg tcagctcatt actggttctt gactatggta
    20761 ataatatcca taccagaggt ggattcccat ctaacagtca acagatagct cagtttgcat
    20821 cttatgctgc gtggattgcc gagcgttata aaggtaaggt aaaatattat gaggtttgga
    20881 atgaatggta tcttgggact ggtattagtt cttggtttct aaaaaaagct aaacctgacg
    20941 atgccatcta tttccaattg attaaagcaa cttccgaagc aatcaagcgt atcgatcctg
    21001 gtgctaaaat cattgctggt agttttaacc ctttaaaaaa accagagatc gaatggtttg
    21061 ataattatat tgatatgggc gttttgaaat atattgatgg catttcggta catccatatt
    21121 cttatggtaa taaggacatt aaattacgaa ctccagaagg aaatatatca gctatcgatc
    21181 gttatgagca gcatttgaaa aataagaccg gcgaaaatat tgatctgtat attacggaag
    21241 ttggctatcc tacaaactcc tctaaggggg gagtagagcc ggagttggct gcgcaatata
    21301 tggtaaagta tactttcttg gctaaacaaa gagattatat caaagggatt tggtggtaca
    21361 ccttgatgaa tagtgcagat aatacttcga acagagaatc taatttcgga atactcatgc
    21421 ataatgaatc tgaaaaacca tcggctaaat gccttaagca aaatgaacaa ctgattgctg
    21481 gagctttaac caatcaaaaa aatgcttctt cctcaattag ctgtagtggt cagtaagtta
    21541 actatctagc acaaattaaa ctaccagaaa atttaagtat gtcttactat acgaacatgc
    21601 tcattccgcg aattatcgca gttaactcac ctgacaggag tatgtaatgt ccaagcaaca
    21661 gatcggggtt gtcggtatgg cagtgatggg gcgtaacctt gcgctcaaca tcgagagccg
    21721 tggttatacc gtctccgttt ttaaccgctc ccgtgaaaag accgaagaag tgattgccga
    21781 gaatccaggc aagaaactgg tcccacatta tacagtgcaa gagtttgttg aatcactcga
    21841 aactccgcgc cgtattctgt tgatggtgaa ggcaggtgca ggcactgata gtgccatcga
    21901 ctctctgaag ccttacctgg acaagggtga catcatcatt gatggtggta acaccttctt
    21961 ccaggatact attcgtcgta atcgtgaact ttctgcagaa ggctttaact tcataggcac
    22021 cggtgtatcc ggcggtgaag agggagcgct taaaggccct tctatcatgc ctggaggtca
    22081 gaaagaagct tatgagcttg ttgcaccaat tctcaagcag attgccgcac tcgcagaaga
    22141 cggtgagccg tgcgtaacct atataggtgc tgatggtgct ggtcattatg tcaaaatggt
    22201 tcacaacggt attgaatacg gcgatatgca gctgattgct gaagcctacg ctttactgaa
    22261 aggtgggctc gcgctttcga atgaagagct tgcgcaaact ttcaccgaat ggaatgaagg
    22321 tgagctgagc agctatctga ttgacatcac caaagacatc ttcaccaaaa aggatgaaga
    22381 gggtacatac ctggttgacg tgatccttga tgaagcagca aacaaaggta ccggtaagtg
    22441 gaccagccag agctctctgg acttgggcga accgctatcg cttatcactg agtcagtatt
    22501 tgctcgctat atctcctctt tgaaagacca gcgtgttgct gcctctaaag tgctgactgg
    22561 gccgcaagcg aagactgcag acaataaagc agagttcgtt gaaaaagttc gtcgcgctct
    22621 ttatctgggc aaaatcgtct cttacgctca aggtttctca cagctgcgtg cagcatctga
    22681 tgagtatcac tgggatctaa actacggcga gattgctaaa atcttccgtg caggctgcat
    22741 catccgtgct cagttcctgc agaagatcac tgatgcctat gagcagaatg ctggcattgc
    22801 caacctgctg ctggcgcctt acttcaccca gatcgctgat gattatcagc aagcgttgcg
    22861 cgatgtggtt gcatacgcag tgcagaatgg tatcccggtt ccaaccttct ctgcggctat
    22921 tgcctattac gatagctatc gttccgctgt tctgcctgcg aacctgatcc aggcgcagcg
    22981 tgattatttc ggtgcacata cctacaaacg tactgataaa gaaggaatct tccacacaga
    23041 gtggttagat tagcctattc tgctttaata tttgaggcca ttcttttaag tagatatatt
    23101 ttaaaggaat catctaagac actaacaata aagttagtgt ctttttaatt catatgttaa
    23161 tgagttggtt tgaatttcgt acgtttaaga ttttgaagtg gttatttcga atcgaatagc
    23221 tgatgaatat tccgaggtag caggcaaggt ttatactcgt gatctatttg gtaatgatta
    23281 atactgattg ttatagctgt gtgcatgatt gtatagtacg taatgcatct cagtctttag
    23341 tattattgtt catcgagatt ttataagtgt aattaacttt actactgatg ttttacaatg
    23401 tcagtgggtt aaatgcagag gctgaaaaat tatgaaatat ttagttactg gtgccgccgg
    23461 ttttattggg ttccatatta gtcaacgact tttaaaagac ggtcatcagg ttacaggaat
    23521 tgataatctc aacgattatt atgatgtcaa cctgaagcag gcccgtctcg atttactgca
    23581 atctcccctg ttcagtttcc ataaaatcga tcttgctgat cgagccaaaa tggaacaact
    23641 tttcttttca gaaaagtttg atcgtgttat tcatcttgct gcccaagcgg gagtacgtta
    23701 ctcactcgaa aatccgcatg cgtatgctga ctcgaacctt cttggcttcc tgaatattct
    23761 ggaaggctgc cgacataaca aagttaagca tctggtttat gcgtcttcca gttcagttta
    23821 cggcctgaac cgtaaaatgc cgttctcaac cgatgattct gttgatcatc cagtgtcgtt
    23881 atatgcggca actaagaaag ccaatgagct gatggcgcat acctactctc acctttacgg
    23941 gataccgact accggcctgc gtttcttcac cgtatacggc ccgtggggtc gcccggatat
    24001 ggcgttgttc aaattcacca aagccatgct ggaaggtaag agtattgacg tgtacaacta
    24061 cggcaagatg aagcgtgact tcacctacat tgatgatatt gtagaagcta tcattcggtt
    24121 gcagaatgtc cttccaaatg aagattcaga gtggagcgta gaaagtggtt cgccggcaac
    24181 cagttcagcc ccgtaccgag tttataatat cggtaatagc tcaccggttg aattgatgga
    24241 ttatattaca gcactggaag aagcgctggg aatgatcgct gagaaaaata tgatgccgat
    24301 gcaacctggt gatgtaatgg aaaccagtgc tgatacggcg gctttatata atactattga
    24361 ttttaaaccc gaaacttctg tgaaaaaggg agttggaagt tttgtcgatt ggtataaaaa
    24421 atattaccaa tagtgattgg tgtcgttaat gtatcaggtt gaggatatat tccttttgtt
    24481 ttaaatatgt tctgaaacat tataatttaa atctaaggaa aaattacgat cataattttt
    24541 taaaattaga tgcagccatg ctgccgaata agtataatag tttaatatga tctgtggctc
    24601 aagttatatg tcttagtttt ttacggctgg gttttattct cactatggga gtgtcgatgt
    24661 tatttaattg gtgctattat tgtgacgcaa tactttacgt gcgttttaac tttcccaaaa
    24721 attgatccca atgttcactg atttcgttaa atattttaga tgtaagtatt ttatgttata
    24781 ttaaagtaat taataattat aatgcttgat atttataata atatgttgat tataaggttt
    24841 ttataaagga ttgtgatgtt ctaatagctt gagttacaca taaagatata cgagaagttc
    24901 atttttttaa attgtagtaa taatgaattt taagtttatt gcataaaagt taaggctata
    24961 ataattgagt tggtttggtt gaaataatat ttcttgcatc atgttaagta atgttaattt
    25021 ggccttagtg aatgctgttt gaattgttat atgttcctat tttgattgta atactatctc
    25081 ttagagcttt ttgacattca gccctaatat ccgtgggttt gattattgca acatcagtgc
    25141 tttcaattgg gactttgatt gctgcggtta tgcagtagag ccatagggca gatatgtgga
    25201 attatgcatt accttatggc tattccttga cttcccatct ttctgagagt aaaagcgcca
    25261 caagtgttga ttaccagggt ggctaatatg ccaccgtcca gttaactgat taaagtgtga
    25321 tcgaatgaaa attactattt ccggtaccgg ttatgttggt ttatcgaacg gcatcctgat
    25381 tgcgcaaaac cacgaagtgg tcgcgcttga tatcgttcag tccaaagtag atatgcttaa
    25441 ccagaagatt tctccgattg tcgacaaaga gatccaggaa tatctggccg aaaagccgtt
    25501 gaattttcgt gcgacaactg acaagcagga cgcttatcgt aatgctgact atgtcattat
    25561 cgctaccccg actgactacg atccgaaaac gaactatttt aatacatcta ccgttgaagc
    25621 cgtcattcgt gatgtagcag agatcaaccc gaacgcggac cgtccagtta actgattaaa
    25681 gtgtgatcga atgaaaattc aacggctttt cggccagata ttcctggatc tctttgtcga
    25741 caatcggaga aatcttctgg ttaagcatat ctactttgga ctgaacgata tcaagcgcga
    25801 ccacttcgtg gttttgcgca atcaggatgc
//
