LOCUS       AB924610               26970 bp    DNA     linear   BCT 28-OCT-2015
DEFINITION  Klebsiella sp. 325 DNA, capsular polysaccharide synthesis gene
            cluster, serotype: K79.
ACCESSION   AB924610
VERSION     AB924610.1
KEYWORDS    .
SOURCE      Klebsiella sp. 325
  ORGANISM  Klebsiella sp. 325
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella.
REFERENCE   1
  AUTHORS   Pan,Y.J., Lin,T.L., Chen,C.T., Chen,Y.Y., Hsieh,P.F., Hsu,C.R.,
            Wu,M.C. and Wang,J.T.
  TITLE     Genetic analysis of capsular polysaccharide synthesis gene clusters
            in 79 capsular types of Klebsiella spp
  JOURNAL   Sci Rep 5, 15573 (2015)
   PUBMED   26493302
  REMARK    DOI:10.1038/srep15573
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26970)
  AUTHORS   Pan,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2014) Contact:Yi-Jiun Pan National Taiwan
            University College of Medicine, Department of Microbiology; 1, Sec
            1, Jen-Ai Rd., Taipei 100, Taiwan
FEATURES             Location/Qualifiers
     source          1..26970
                     /organism="Klebsiella sp. 325"
                     /mol_type="genomic DNA"
                     /strain="325"
                     /serotype="K79"
                     /db_xref="taxon:1339200"
     gene            1799..2701
                     /gene="galF"
     CDS             1799..2701
                     /gene="galF"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose pyrophosphorylase"
                     /protein_id="BAT24378.1"
                     /translation="MDMRMASLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMVQYI
                     VDEIVAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVT
                     IMNVRQAQPLGLGHSILCARPIVGDNPFVVVLPDIVLDDASADPLRYNLAAMVARFNE
                     TGRSQVLAKRMDGDLSEYSVIQTKDPLNVEGQIGRIVEFIEKPDEPQTLDSDLMAVGR
                     YVLSADVWAELERTQPGAWGRIQLTDAIAELAKKQPVDAMLMTGESYDCGKKMGYMQA
                     FVNYGLRNHKEGTKFRESIKKLLA"
     gene            3175..3804
                     /gene="cpsACP"
     CDS             3175..3804
                     /gene="cpsACP"
                     /note="orf2"
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase homologue"
                     /protein_id="BAT24379.1"
                     /translation="MNWQWVSFFGDSTVLLPSAAAVFMVLFLRRPSRQIAWQWGLLFG
                     ITGAIVSASKLAFMGWGIGIRELDFTGFSGHTALSTAFWPIFLWLLCARGSIALRRTA
                     MVIGYLLAILVGYSRLAIHAHSPSEVIAGLLLGACGSALFLLLQRNSSRVVDAQLSWG
                     GVLSLIIIPVVLLNTGAKAPTQSLLGEIAVKLGPLEKPFTRADLHKRFY"
     gene            4764..6203
                     /gene="wzi"
     CDS             4764..6203
                     /gene="wzi"
                     /codon_start=1
                     /transl_table=11
                     /product="surface assembly of capsule"
                     /protein_id="BAT24380.1"
                     /translation="MMKIARLALALGLLTSVSAQVYASGLVLNDNELRNDLSWLSDRG
                     VIQLSLSTWPLSQEEITRALKKAKPSYSSEQVVLARINQRLSSLKADFRVSGYTSTDQ
                     PGTPQGFAQSQPADNSLSLSFNNSGDWWDVHLQGNVEGGERISNGSRFNANGAYGAVK
                     FWNQWLSFGQMPQWWGPGYEGSLIRGDAMRPMTGFLMQRAEQAAPETWWLRWIGPWQY
                     QISASQMNQYTAVPHTKIIGGRLTFTPFQSLELGASRTMQWGGEGRPQSLSNFWDGFT
                     GKDNTTANDPNEPGNQLAGFDFKLKLEPTLGLPVSLYGQMIGEDESGFLPSANMYLGG
                     VEGHHGWGKDAVNWYVEAHDTRSNMSRTNYIYTHHIYKDGYYQQGYPLGDAMGGDGQL
                     LAGKVELVTEDNQRWSTRLVYAKVNPKDQSINKAFPHSDTLKGVQLGWSGDVYKTVRL
                     NTSLWYTNADHSDSDDVGASAGIEIPFSL"
     gene            6337..7473
                     /gene="wza"
     CDS             6337..7473
                     /gene="wza"
                     /codon_start=1
                     /transl_table=11
                     /product="putative capsule polysaccharide export protein"
                     /protein_id="BAT24381.1"
                     /translation="MKKKMVRFSALALAISFLSACTIIPGQGLNSLRKNVVELPDSDY
                     DLDKLVNVYPMTPGLIEQLRPTSVMARPNAQLDSLLKNYEYRIGVGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNSDGTIFYPYIGKVQVAGKTLAEIRQIIASRLTTYIESPQ
                     VDISVAAFRSQKAYVTGEVVKSGQQPITNIPLTVMDAINNAGGLAPDADWRNVVLTHN
                     GKDTKISLYALMQKGDLTENHLLYPGDILFVPRNDDLKVFVMGEVGKQSTMKMDRSGM
                     TLAEALGNAEGMSQAFSDATGVFVVRQLKGDKQGKIANVYQLNAQDASAMVLGTEFQL
                     QPYDIVYVTTAPLVRWNRVISQLVPTISGVHDMTETVKFVKDMR"
     gene            7473..7907
                     /gene="wzb"
     CDS             7473..7907
                     /gene="wzb"
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="BAT24382.1"
                     /translation="MFDSILVVCTGNICRSPIGERYLRNLLPDKKIDSAGTGALIEHA
                     ADNSAIKVAQNHGLSLEGHHSRQFTSSLGRQYDLILAMEKSHIEQIGHIAPEARGKTM
                     LFGHWLEQRDIPDPYRKSDEAFLSVYKLIEQAGKLWAQKLGA"
     gene            7923..10085
                     /gene="wzc"
     CDS             7923..10085
                     /gene="wzc"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="BAT24383.1"
                     /translation="MSSTTNKTTSKDADEIDLGRLIGEFIDHRKLIISVTSLFTLIAL
                     IYAILATPIYQADALIQVEQKQANAILSNLSQMLPDSQPQSAPEIALIRSRMILGKTV
                     DDLNLQARVKQKYFPILGRGFARLAGDKAGSLSISRLYVPENGNDIPEILLTVKDKNN
                     FSVSVGGFTLNGKVGELIDERGISLKVDEISAKPGTEFIIAYVSRLKAIADLQGDMAV
                     ADQGKDTGMLTLSLTGDNPVLIERILNSISENYLAQNIARQAAQDAKSLEFLSKQLPQ
                     VRSDLDQAEDKLNQYRRKSDSVDLSLEAKSVLDQIVNVDNQLNELTFRESEISQLYTK
                     EHPTYKALMEKRKTLQDEKVKLNKRVSAMPETQQEILRLSRDVESGRAVYMQLLNRQQ
                     ELNIAKSSAIGNVRIIDNAVTQPKPVKPKKIVIILIGIIFGIMVSAGIVLLRVFLRRG
                     IETPEQLEELGINVYASIPVAETFTKSVVQKKGWSKKSTDEIQGFLAVDNPADLAIEA
                     IRGLRTSLHFAMMEARNNVLMISGASPNAGKTFVSSNLAAVISQTGKKVLFIDTDMRK
                     GYTHKLFNENNTNGLSDILSGKVEINRALKKVASGGFDFISRGMAPPNPAELLMHRRF
                     GELLNWASENYDIVVLDTPPILAVTDAAIIGNYVGTTLLVARFELNTAKEIEVSVKRF
                     EQAGVTVKGCILNGVVKKASSYYGYGYSHYGYSYTDKQ"
     gene            10162..11604
                     /gene="wbaP"
     CDS             10162..11604
                     /gene="wbaP"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT24384.1"
                     /translation="MQRGYMTLLVRNIIVSIALAMSDFFSFVISLYLAIGVLSITVGD
                     YETAVSANQLEGWKILHWLLALCCVAWYSMRLRHYFYRKTFWFELKEILRTLVIFAVI
                     EIAVLAFANWSFSRFLWGLTWVFVLLLVPLARMVTKRVLDVFGLWHRETWIIGSGANA
                     QEAYKAINSERNLGLVIVGFVETAKGFSENKNIDGIPVLANDPDWLSSMDKKTQFIVA
                     VESHQSEVRNAWLRNFMIKGYRYISVIPTLRGMPLDSTDMSFIFSHEVMIFRVQQNLA
                     KWSSRILKRLFDIVGSISIIVILSPALIYISRKVKKDGGPAIYGHERIGKGGQSFKCL
                     KFRSMVINSKEVLENLLENDPEAKKEWDATFKLKNDPRITKIGGFLRRTSLDELPQLF
                     NVLKGEMSLVGPRPIITAELERYNEEVDYYLLSKPGMTGLWQVSGRSDVDYETRVYLD
                     AWYVKNWSMWNDIAILFKTIGVVLKKDGAY"
     gene            11639..12550
                     /gene="wcaA"
     CDS             11639..12550
                     /gene="wcaA"
                     /note="HG17; orf8"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT24385.1"
                     /translation="MKYFIAIPTYNGGDIWREVVLNIQRHAPAGLQVQIIDSSSKDDT
                     VSVARKEGFSIESIPSVDFNHGGTRNIAVSKHSDECDIVIFLTQDAIPEAGFIERIIS
                     VFDDPQIACAWGRQLPHNDANPIAQHARYFNYPLESYICRKEDSSTLGLKTVFMSNSF
                     SAYRIKTFQELGGFPSDTILCEDMYYTAKAVLAGYKVAYVADAIVHHSHNYSPLEEFR
                     RYFDIGVFHADEPWIRKQFGGAGGEGKRFVVSEFRYLLKSDLKYIPVAVLNNAMKILG
                     YKLGQWYKYLPKRFIKFFSMHKRFWKF"
     gene            12925..14034
                     /gene="wcuM"
     CDS             12925..14034
                     /gene="wcuM"
                     /note="HG37; orf9"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT24386.1"
                     /translation="MKNMLYVTTVFEDENDGIWKKIKYTLCAYQRLGYLIDFAYRTKA
                     GYVINFGFNSEQSKVERVNEHHKDLFFYNLSKKIIKKYDFLYIRKPFGGASFLFLNFL
                     ISKVKKGGGKVAFEIPTYPYRKEIKSVKNIISERLFQVSKSAYVHKIDLIVYMGESSG
                     NIWGRPALKIANGIDLNKVQILKENLNSVSDEFIFVGVARLSFWHGYDRLIEAVKNYK
                     GNYKIKFIVIGNGEPELSRLNALTKKHALEEKVLFLGAKFGNELDMQYKKAHVCIDSI
                     GRHRSGNQFNSSLKSKEYAAKGLPFIMSHKDDSFENVNFIFNVSPDEEMINIDEIISW
                     YEKLPTNTPVEMRAFAEQFLSWDIQCKKVLENIFY"
     gene            14038..15015
                     /gene="wcuR"
     CDS             14038..15015
                     /gene="wcuR"
                     /note="HG45; orf10"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT24387.1"
                     /translation="MVEMKKIQVLLATYNGSKYVIDQINSILMNFKWVSEYNCSILIS
                     DDSSSDETIQLIKDNFSNIPGVNIISTSRKGGVRNNFTFLINYADGDFIFFCDQDDLW
                     LPSKLRVFMDEFNQRSALNNEPMLIHSDLCVTDSILSPIHTSMFEYQKLNKAPSFSNM
                     IVSNSITGCVLGINKRLLNILKKSSINKSIMHDWYIGIIASSFGEIIYIPKSLILYRQ
                     HENNQVGAKKFSFYEMLSLEKIQNIKQSIWLTKAQAELFLSDFDGQLDKNNEKILKAY
                     ISSFDRNILSRCLTFFKYGFYKYGFARNIVFFIFFVFFAGAIKKQKNIT"
     CDS             15018..16316
                     /note="HG89; orf11"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAT24388.1"
                     /translation="MLRVNMFKTRCYINLRSFLLPFIVFLPTCVLSAENVSSNNIGRI
                     LLKDSNSIDKNVLSSVYASKDTYGMRSNAVVAAFSANPEKPFDFPILGFSGVMQMAKY
                     KDRDSVSLYADNTALPFKSWERVKSANYTATSFTTEESTALNLKPGMLVETGHEPSWS
                     SYIISIVGNKVITSGWVNNSTGHLGIPKDGSGLVVNPITKIWATNFNIFFPEGGRANK
                     GVIQENGLINNNIDNPSTISGLDTVVLPQSKFGGTAAYLARSADSGGKQQWTYGFLSS
                     GSKVSFLSSDSGIHYPEISFHDSSSANNGLVFDGKNKSNSILWKDGNNNITAKIDPTG
                     RISMIGYKTREIKDSSKLTTDFSRYIVENNSEINLILPDSKNIIDGFTLKIVKVGGES
                     SIVNIRTPDNVSINGEMKVLSLSGRWNKEVIYYNKQWFFY"
     gene            16375..17562
                     /gene="wzy"
     CDS             16375..17562
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="BAT24389.1"
                     /translation="MPYFFYSSTLFLYFIISLFLLSLSVASILVKSKKMDSVVFILIS
                     IMMICFYGFRFPGTVDIKMYLQNFDALSSFQDFQWGIGFYMLMKSIKIFDASHTAYVF
                     YSALYFVIAFVAVGFFYCKGKYYKSLFLISSFYSWSILDLAVNTYRQGIAVPFILLGL
                     YFLTQRKYILSSIVICVSLTLHWGSAVILLLYIFAIYLSKRIFLLKIVSFLTLTLFTI
                     SFFVNFSIAEMLSTSSILSILQVIFVGVDFDSKVNAYLGGGVLGANFYDMNSLQRLYF
                     SGEIYISLLVFVFFFMTRKRNDYIFTNKKNNFLLIYSFFISVSLYGVILISMTWFIRN
                     FYWVVPVAPILYVMILEYYESSNPKKFKILLLLFVLFSITYSLETFWRTPLIDMSYPS
                     VSI"
     gene            17819..19291
                     /gene="wzxC"
     CDS             17819..19291
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="BAT24390.1"
                     /translation="MSLKEKTLNAVKWNLLSTIVTVSLGMVSLWALSHILSVEQYGVI
                     SAALIITNFINMLLDFGISNSIVRSQTVERIELASLSVVNIFMGIAAFILTFIFSENI
                     AGVFGGSENLRFQVEIVSFGFIFIALGLQPKALLTKDMEFGLLSKIVIIVAITNFIIA
                     VTLAFIFHEAWCVAVAFLVSSIIGSLIARFCARKLMDYGAGFQLKAIRKHFRYGIQLV
                     IDSLINQISINTYPVLMSRLISFAAIGGYNISYSISIALFERLNPILSHALFPAFSKI
                     GNDEKKLQSSFLKVTIFSSMVNFPMLIGMMLASTQIVRIFFDEKWSFIPPIVQILCIV
                     GVLRSLETPVISVLLVKAQMYRNIYLGIGKLLTGIPLAWFLGTRFGITGIVYGFLIIQ
                     VVNTTLGYFYLLKPSLGISGLKYLKSILIPAIHVLPMVVGGLILNKMELIDNQFAHLF
                     ILIALCFVLYSVTIFMSPVDIVREFRATIINNFMTKALKK"
     gene            19288..20235
                     /gene="wcuU"
     CDS             19288..20235
                     /gene="wcuU"
                     /note="HG52; orf14"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT24391.1"
                     /translation="MKLSIIIPCYNCAGRINKLLTLIYQQVKDNDNVEVVLVNDGSTD
                     NTRNVISDFLQNNVSDEFILINTENRGAAGAREKALEFATGEYIFFCDSDDLIAHNFV
                     QTILSGCESCPDVIYFSSEMISSGEDYYKIADKVLFKDNTVFTSPDEFLFYQLKRGYW
                     TAAVWTYVFRRNIAVLQHATFSARRAHEDHLFTAKVVLSANKIICLKDVLYFQVLTIG
                     SLTNSKKNLDYISERYLAFVETRYYLKEKCKKETVLLYETWTLRSIISLFLENKNLLL
                     NALLSFSVWKSVFTEKVLICKFLFCFLKKKVKYGANKND"
     gene            20213..21067
                     /gene="wcuH"
     CDS             20213..21067
                     /gene="wcuH"
                     /note="HG26; orf15"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="BAT24392.1"
                     /translation="MVQTKMTESKSIILNLTTTSGRLDLCSATLWSLVNQSLLPGRIN
                     LWISAEPYMADEGIQILPDSINRLIKYNDIIKVHYVENTGPYRKIIPALRSCLDEDIL
                     VYADDDVVYSHHWLEYLISFYLENNREYVVSSRLREMKKNFFGLYQSYSLFPLVFEKK
                     VFYTDFIITGVGGCVLERKHISQKYIDLNSFKKIAPKTDDLWISKIIELSGSGVIACP
                     KALDCIMEIQHDIHALNRMNTFFSSQNIISKMIGAFKRRLLGYCGVSLSNNDVMIKTI
                     NSFFKRNI"
     gene            21413..22819
                     /gene="gnd"
     CDS             21413..22819
                     /gene="gnd"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate-6-phosphate dehydrogenase"
                     /protein_id="BAT24393.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVSA
                     ENPGKKLVPYYTVQEFVESLETPRRILLMVKAGAGTDSAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILEQIA
                     ARAEDGEPCVAYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLALSNEELATT
                     FTEWNTGELSSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLTGPEAQPAGDKAEFVEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYHWDLNYGEIAKIFRAGCIIRAQFLQKITDAYEQNASIANLLLAPY
                     FKQIADEYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRTDKEGVFHTEWME"
     gene            23061..24125
                     /gene="rmlB"
     CDS             23061..24125
                     /gene="rmlB"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose-4,6-dehydratase"
                     /protein_id="BAT24394.1"
                     /translation="MKILVTGGAGFIGSAVVRHIIENTQDEVRVMDCLTYAGNLESLA
                     TVTDSERYSFTQTDITDAKSVSEQLSDFRPDIVMHLAAESHVDRSIDGPAAFIQTNLI
                     GTFTLLEAARHYYSTLDAAQKQAFRFHHISTDEVYGDLHGTDDLFTEETPYAPSSPYS
                     ASKAGSDHLVRAWNRTYGLPVVVTNCSNNYGPYHFPEKLIPLTILNALAGKPLPVYGN
                     GEQIRDWLYVEDHARALYKVATEGESGETYNIGGHNERKNIDVVRTICAILDKVVEQK
                     PGNISQFADLITFVKDRPGHDLRYAIDAAKIQRDLGWVPQETFESGIEKTVHWYLNNQ
                     NWWQRVLDGSYAGERLGLNN"
     gene            24164..25033
                     /gene="rmlA"
     CDS             24164..25033
                     /gene="rmlA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyl-transferase"
                     /protein_id="BAT24395.1"
                     /translation="MKGIVLAGGSGTRLYPITQGVSKQLLPIYDKPMIYYPVSVLMLS
                     GIRDILIITTPEDMPAFQRLLGDGSQFGVNFSYAIQPYQDGLAQAFIIGEKFIGNDAC
                     ALVLGDNIYFGQSFGKKLEAAASKTSGATVFGYQVLDPERFGVVEFDENFRALSIEEK
                     PLKPKSDWAVTGLYFYDNNVVEMAKEVKPSERGELEITTLNQMYLDRGDLQVELLGRG
                     FAWLDTGTHDSLIEASQFIHTIEKRQGMKVACLEEIAYRNDWLSAEGVAAQAERLKKT
                     EYGAYLKRLLNER"
     gene            25066..25956
                     /gene="rmlD"
     CDS             25066..25956
                     /gene="rmlD"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-L-mannose dehydrogenase/
                     dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAT24396.1"
                     /translation="MKILLIGKNGQVGWELQRSLSTLGEVVAVDYFDKELCGDLTNLE
                     GIAQTVRQVKPDVIVNAAAHTAVDKAESERELSDLLNDKGVAVLAEESAKLGALMVHY
                     STDYVFDGLGSHYRQEDEATGPLNVYGETKRAGEIALEQGNPRHLIFRTSWVYATRGA
                     NFAKTMLRLAAEKETLSIINDQHGAPTGAELLADCTAIAIREELRNKAVAGTYHLVAS
                     GETSWYDYARFVFDVARANGVQLAINEVNGIPTTAYPTPAKRPLNSRLSNEKFQRVFG
                     VTLPDWRQGVERVVVEVSGK"
     gene            25968..26522
                     /gene="rmlC"
     CDS             25968..26522
                     /gene="rmlC"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-D-glucose-3,5-epimerase"
                     /protein_id="BAT24397.1"
                     /translation="MNIIKTDIPDVLIFEPRVFGDARGFFFESFSSKVFDEAVGRHVE
                     FVQDNHSQSQKGVLRGLHYQLDPHSQGKLVRCVEGEVFDVAVDIRRSSPTFGQWVGAV
                     LSAENKRQLWIPEGFAHGFMALSETVQFVYKATNYYAPQSERSILWNDPDIGINWPEL
                     DGCTLSLSEKDMQAHTLATAEVYK"
BASE COUNT     7670 a   4987 c   6225 g   8088 t
ORIGIN
        1 gggggccggg tgaattagca cccgctcatc atccggcgtt cctgggggtt gaacagcggg
       61 ttatcggcct ggctgtcgat cagcgcggcc gtatcgctgc tgagctcggc gtgttcttta
      121 tgcccgctaa gtagattcat caccgcttcg gtcgtgcgct ggcgtagcgt gagattggcg
      181 gagaggaagc gacggcggtt gaacagcgcc agctggttca gcgactcaat gatgacggag
      241 aagccgatgg ccgcatacag ataacctttc gggatgggga acccaaaccc ttcggcaatc
      301 aggctgaaac caatcatcag caggaaactc agacagagaa tcacgatagt cgggtggctg
      361 ttgacaaacc gcgtcagcgc tttgctggcg agcagcatca aactcatggc aataaccacc
      421 gccgccatca tcaccgccag atggtcgacc atgcctacgg cggtgatcac cgaatcgagg
      481 gagaaaatgg catccagtac cacaatctga gcgaccaccc cccagaacct cgcgcccttg
      541 cgctgaaccg gattatcgct gtctttgccc tccagccgtt cattcagctc aacggtggct
      601 ttaaacagca ggaataaccc accagacaac ataatcaaat ctcgcgcgct aaagctgagg
      661 tcgtggtagg tgaacagcgg tgtggtcagg gtgaccagcc aggatatcga ggcgagcagc
      721 agcagacgca ttagcatcgc cagcagcagg ccaatcaccc gcgcgcggtc acgctgagtc
      781 ggagggagtt tttccgcgag gatcgcgata aaaacaaggt tatcaatacc gaggaccagc
      841 tctataacca ccagcgttat gagaccggcc caaattgagg ggtcggcaat ccattccatc
      901 attagttaaa acctatacta cctgagagtg ccatccgacg atcatggata agcgacagat
      961 aaattgcaat atattctcgt cttatgacgt cgggcgggta cagctgcggg agaaatgctg
     1021 cggatcgcaa tattagactg catgaattat agacgcgcga gcttattttt tatgcaaata
     1081 agcttattaa taaaaggcat gactgtggac gactgaatat aaacttgcaa aaagtgtact
     1141 ggatcaataa tgccggttat tgctctctct ggtcgcatag cggtatgaaa atcagacgga
     1201 ttcagacgcc gggggtaaac gcccaattca attacttaat cgtagcgatc cagtttttga
     1261 tactactgaa tgtcgtggct tgcaaaatat cttgtttaat cagacgatat cagtagcttt
     1321 taatcaggtg taaaagtcag tgccgatgga tgacatggat agcgggcaag aggcgaggga
     1381 gggcatgatg agcgcagcgg tgagctttct gcgctatttt ctattgaaaa tagcgcctgc
     1441 agattatttt tatgaattat ggaccggcgt tcataagaat aaatcctctt tttccctacg
     1501 ttttgcgaat tatccagatg tatcctctac agtgttctct accgggaatg cagcgataag
     1561 tcctgctggt ggtacgagaa cagaagaaaa tcctgaggca gggcgctata tggcatctgc
     1621 ggcatcagaa ttttcttaaa ccgctctgtc ggacctaata ctttgcgtgt attctctgat
     1681 gaaacatgta gtttcggaat tttgctggaa gtcggactga gagcaaaacg gtaatatcac
     1741 agattgatac caggagaacc tgtaatcagg tgggtatcga agatttatca ctatatgggt
     1801 ggatatgaga atggcaagtt tgaaagcagt tattccggta gccggattgg ggatgcatat
     1861 gttgccggcc accaaggcga ttccgaagga gatgctgcca atcgttgata agccaatggt
     1921 tcagtatatc gtcgacgaga ttgtggctgc aggcatcaag gagattgtac tggttaccca
     1981 ctcgtctaag aatgccgtgg aaaaccattt cgatacctcc tatgaactgg aagcgctgct
     2041 tgagcagcgt gtcaaacgtc agctgctggc tgaggtacag gcaatctgcc cgccgggcgt
     2101 gaccatcatg aacgtacgcc aggcgcagcc gctgggactg ggacactcca ttctctgcgc
     2161 gcgcccaatc gtcggtgata acccatttgt tgtggtgctg ccggacatcg ttctggatga
     2221 tgccagtgct gacccgttgc gctataacct ggcagccatg gtggcccgct ttaacgaaac
     2281 cgggcgtagt caggtgctgg ccaagagaat ggacggcgac ctgtcggagt attcggtgat
     2341 ccagaccaaa gacccgctga atgtggaagg gcagattggc agaatcgttg agtttatcga
     2401 gaagcctgac gagccgcaga cgctggattc cgatctgatg gcggtagggc gctatgttct
     2461 ttccgccgat gtgtgggctg agctggagcg cactcaaccc ggcgcatggg gccgtattca
     2521 gctgaccgat gcgattgctg aactggcgaa gaagcagccc gttgacgcca tgttaatgac
     2581 cggcgaaagc tacgactgcg ggaaaaaaat gggctatatg caggccttcg taaactacgg
     2641 gctgcgtaac cataaagaag gcacgaaatt ccgcgagagc attaagaagt tactcgcgta
     2701 aataggctac gccggatttc agaagtgtga aaatgtaggg tttacagaag tatgtggcat
     2761 aagaccgcga tgttgcatgc ttctgtagat aaccctgctg attaaaacag catattttag
     2821 acaaatgtta atcaatataa atcagatggt tatgctgatt tgctgaaaca cacttaatgt
     2881 gtaaacaaaa agcgacttca gagacatctg gttgttgtgc tggccctcct gtgatggaat
     2941 ggtcggagta gcataatttt atgtttgcta ataatgagtt agtcagaatc ttcttaaaaa
     3001 aatatgcatg tcgctggctg tcataaaaaa ataaaacttg actgagatca tgcttacgca
     3061 ttaaacaaca gtgatgcatg cataaaaatg tgaagttatc ggatgtgtat gcccatacca
     3121 acgtcatgga caaaggcgct gcgaactgga aaatcgtcaa aggatgaaaa ataaatgaac
     3181 tggcagtggg tctctttttt tggcgatagt accgtgctgt tacccagcgc ggcagcagtg
     3241 ttcatggttt tatttctgcg caggccttcc agacagattg cctggcagtg gggattgctg
     3301 tttggtatta ccggcgccat cgtcagtgca tcaaaactgg cttttatggg ctggggcatc
     3361 ggcatccgcg agttagattt tacgggtttt agcgggcaca ccgctttatc taccgccttc
     3421 tggcccattt tcttatggct gctctgtgcc cgcggtagca ttgctttacg ccggactgcc
     3481 atggttatag ggtatttgct ggctatcctc gtggggtatt cccgtctggc gattcatgcc
     3541 cactccccat ctgaagtgat tgccgggctg ctgcttggcg cctgcggtag cgcgctgttt
     3601 ctgctgctgc agcggaattc gtcgcgtgtg gtcgatgcac agctctcctg gggcggggtg
     3661 ctcagtctga ttatcatccc cgtcgtgctg ctaaataccg gcgctaaagc gccaactcag
     3721 tctctgctgg gtgaaatagc cgttaagctg ggtccgctgg aaaagccctt tacccgcgcg
     3781 gatttgcata agcgttttta ctgaatgtgc tgctgacgat gaatgggacc agagaaaata
     3841 atagaatcag tcccggtttc gtacattcat attcgtgaaa taaatagttg ctactacatt
     3901 ctgcagcaat atttttgctg gcacaggaaa taacgtggct gagaacaatc ctaaatagac
     3961 aggctgcccc ttattcttga aattaaatta tgtttgtcaa gtataaaaaa tgaatggcag
     4021 gtattaattt ttgtagttga cggaagtgac gagaattaac gtggttaata tactcatccg
     4081 ataaaagtct taaaaaacat agtgttgatt tggttttggt gcgtaagcat gcatcttgag
     4141 ctggatcggc gagatattat taaacaatct tattgaggtg tcgtccgctt gtcggaggag
     4201 tcagattggg ttgttttgat aagcgaatag ttgtcatttt tactcccatt tgccggcaga
     4261 atctcgtaaa cttgatgccg caaaaatatt gtcagtgact aataatccgg cgggcgctgc
     4321 gccagcaaaa atgtataaat gaagtacagt gcattggtag ctgttaagcc aagggcggta
     4381 gcgtatcgaa accgtcagcg tcaattctgc agtcatcttc tatatgttct aaattcctaa
     4441 aaccggttgc gacggatgat tatccgcaag caccgtatat aatcggcact ctttctgact
     4501 caacggtgtt ttatccctct gtctgactta agatagccca tgtccatggt gagtggtgat
     4561 cggtgtgagg ggcgtcgctg gcgttttgac tgtggcactg acatttcaaa tagtgcgtgg
     4621 ctgattacgt tcgaagggac tgcttattgc atcatcactg ctgaacaaac atactacgac
     4681 tggcgtcagc gtgcgctctc taaactcata ttccccatga ctcgccagct tgcggaaacg
     4741 gggctaaaaa tggatcttgt ataatgatga aaatcgcgcg tcttgcactt gctttggggc
     4801 tgttgacatc ggtgagtgcg caggtttatg cctctggtct ggtactcaat gataacgaac
     4861 tgcgtaacga tctctcctgg ctgtctgacc ggggagttat ccagcttagc ctttcgacct
     4921 ggcccctgag tcaggaagag attacccggg cgttaaaaaa ggccaaaccc tcctattctt
     4981 ctgagcaggt ggtgctggcg cgtattaatc agcggctttc atcactgaag gctgatttcc
     5041 gcgtcagcgg ctacacctct accgatcagc cgggaacacc gcagggcttt gcgcaaagcc
     5101 aaccagcgga taactcgcta tcgctgtcct ttaataacag cggcgactgg tgggatgttc
     5161 atctgcaggg caatgtggaa ggcggtgagc gtatcagcaa cggctcccgg ttcaatgcca
     5221 acggcgcgta cggcgcggtg aagttctgga accagtggct gtcgttcggc cagatgccgc
     5281 agtggtgggg gcctggctat gaagggagtc tgatccgcgg ggatgcgatg cggccaatga
     5341 ccggcttcct gatgcagcgc gctgagcagg cggcgccgga aacctggtgg ctgcgctgga
     5401 ttggtccctg gcagtatcag atctctgcca gccagatgaa ccagtatacc gcggtacccc
     5461 atactaagat tatcggtggg cggttgacct tcaccccgtt ccagtctctg gaactgggcg
     5521 cttcacggac tatgcagtgg ggcggggaag ggcgcccgca atcgctgagt aatttctggg
     5581 atggttttac cgggaaagac aataccacgg caaacgatcc gaatgagcct ggcaaccagc
     5641 tggcagggtt tgactttaag ctgaaactag aaccgactct cggtttaccc gttagcttat
     5701 atggccagat gattggtgag gatgaatcag gttttttgcc ttccgctaat atgtaccttg
     5761 gtggtgtgga aggacatcat ggctggggga aagatgcggt gaactggtat gtggaggctc
     5821 acgatacgcg cagcaatatg agtcgaacca actatatcta tacccaccat atctataaag
     5881 atggctacta tcagcagggt tacccgctgg gagacgcgat gggaggggat ggtcaactac
     5941 ttgcaggtaa agttgaactg gtgaccgaag ataatcagcg ctggagcact cgtctggtct
     6001 atgccaaagt gaacccgaag gatcaatcaa ttaataaggc gttcccgcac tccgatacat
     6061 tgaaaggtgt acagttgggg tggagtgggg atgtctataa gaccgttcgt ctgaatacgt
     6121 cgctgtggta taccaatgcg gaccatagcg atagcgatga tgttggcgca agcgccggga
     6181 tcgagatccc atttagttta taggctaaat gctacaggaa gtcaggagaa tggagtttag
     6241 cctaccattc tccgcgtgca gccagacagg aataaactgg tggacgatat gtagctcagg
     6301 cattggcaaa ttttagttta ctgatgatgt gacattatga agaaaaaaat ggttagattt
     6361 tcggcattag cattggcaat aagtttttta tcggcttgta ccattattcc tggccagggg
     6421 ttgaacagcc tacgtaagaa tgtggttgaa ttgccggata gcgattatga cctggataaa
     6481 ctggttaacg tctatccgat gacgccgggg ttaattgagc aactgcgtcc gacaagcgtg
     6541 atggcacggc caaatgcgca actggatagc ctgcttaaaa attatgagta ccggattggc
     6601 gtgggcgatg tgctgatggt aaccgtctgg gatcaccctg aactgaccac gcctgccggt
     6661 cagtaccgca gcgccagcga taccggcaac tgggtcaatt ctgacggtac gattttctat
     6721 ccttatattg gtaaggttca ggttgcggga aaaacattag ctgaaatcag acaaatcatt
     6781 gccagtcgac tgacgaccta tattgaaagc ccgcaggttg atattagcgt tgccgcgttt
     6841 cggtcgcaaa aggcctatgt gactggtgaa gtggtaaaat cgggtcagca gccaatcacg
     6901 aatatccctt taactgttat ggatgctatc aataatgctg gcggtcttgc gccggatgct
     6961 gactggcgca atgttgtcct gacccataat ggcaaagata ccaaaatttc cctgtatgcc
     7021 ctgatgcaaa aaggtgattt gaccgagaac cacctgctgt atcccggcga tattcttttt
     7081 gttccacgta atgacgacct gaaagtcttc gttatggggg aagttggcaa gcaaagtacg
     7141 atgaagatgg accgcagtgg tatgaccctt gcggaggcgc tgggaaatgc tgaaggcatg
     7201 tcgcaagcat ttagtgacgc taccggagtc ttcgttgttc gtcagttaaa aggcgataaa
     7261 caaggtaaga tcgctaatgt ttatcagctt aacgcacagg atgcttcggc gatggtgctg
     7321 ggcactgagt tccagttaca gccgtatgat attgtctatg tcaccacagc tccgcttgta
     7381 cgctggaacc gtgtgatatc acagcttgta ccgacgatta gcggtgtaca tgatatgact
     7441 gaaaccgtaa aattcgtcaa ggatatgcgc taatgtttga ctctattctt gtcgtttgca
     7501 caggcaatat ttgccgttct ccgatcggag aacggtattt gcgaaattta ttacctgata
     7561 aaaaaatcga ttcagcagga actggagcac tcattgagca tgcggctgac aatagtgcga
     7621 tcaaggttgc tcagaatcat ggattatctt tggaggggca tcactccagg cagtttacat
     7681 catcccttgg gcgccagtac gatttgatat tagcaatgga aaaatcccat attgagcaga
     7741 tagggcatat agcacctgaa gccagaggca aaacgatgct gtttggtcac tggctggagc
     7801 aacgggatat acccgatcct tatcgcaaaa gtgacgaagc cttcttatca gtttataaac
     7861 ttattgagca ggccggtaaa ctttgggccc aaaagttagg tgcataattc aggaaaaatc
     7921 gcatgtcatc aactacgaat aaaactacat ctaaagatgc agatgaaatt gatttaggtc
     7981 gccttattgg cgagtttata gaccaccgaa agcttattat ttctgttact tctctcttta
     8041 cactaatcgc attaatttac gctattttgg caacgccaat ataccaggct gatgctttaa
     8101 tccaggttga acagaaacag gcgaatgcaa tacttagcaa tcttagtcag atgcttccgg
     8161 atagccaacc ccaatcggcc ccagaaattg cgttgattcg ctccaggatg atattaggga
     8221 aaacagttga tgatcttaat ctgcaggcga gggtaaaaca aaaatatttt ccaattttag
     8281 gccgtggttt tgcgcgattg gcaggagata aagcgggtag tctatctatt tctcggctat
     8341 acgtaccgga aaacggcaat gatattcctg agattttatt aactgtcaaa gataaaaata
     8401 acttttctgt ctccgtaggt ggttttactc tcaatggtaa agttggagag ctaattgatg
     8461 agcgaggaat ttcgctcaaa gttgacgaaa ttagtgcaaa gccagggact gaatttataa
     8521 ttgcctatgt tagtcgattg aaggctatag cagaccttca gggcgatatg gccgtggctg
     8581 atcaaggaaa agatactgga atgctcacac tttccttgac cggcgataat ccagtattaa
     8641 ttgaacgtat tcttaatagc atcagtgaaa actatttagc tcagaatatt gcgcggcaag
     8701 ccgcacaaga tgcgaaaagt ctggagtttt taagtaagca actgcctcag gttcgcagtg
     8761 atttggatca ggctgaagat aaattaaacc aataccgaag aaagagcgat tccgttgatt
     8821 tatcgcttga ggcaaaatcc gttcttgatc aaatagttaa tgttgataat cagcttaatg
     8881 aattaacttt ccgtgagtca gaaatatccc agctttatac caaggaacat ccgacctata
     8941 aggcattgat ggagaaaaga aagactctac aagatgaaaa agttaagctt aataagcgtg
     9001 tgtctgctat gcctgaaaca cagcaggaaa tattgcgttt aagccgtgat gtagagtccg
     9061 gtcgagctgt gtatatgcag ttattaaatc ggcagcaaga gttaaatatt gctaaatcca
     9121 gcgctattgg taatgtgcgt attattgata acgccgtgac ccaacccaaa ccagtaaaac
     9181 ctaagaaaat agttattatt ttgattggta ttatatttgg cataatggtc tctgctggca
     9241 ttgtattact tagagttttt cttcgtcgag gcattgaaac acctgagcag cttgaagagc
     9301 ttgggattaa cgtttatgca agtatcccag ttgcggaaac atttactaaa agtgtagtac
     9361 agaaaaaagg gtggagtaaa aagtctactg atgaaattca gggcttcctg gcagtagata
     9421 acccagcgga tctggcaatt gaagctattc gcggtttacg cacaagcctt catttcgcca
     9481 tgatggaagc aaggaataat gtgctaatga tctctggcgc tagccctaat gcagggaaaa
     9541 cctttgtaag ttcaaacctg gcggctgtaa tttctcagac agggaaaaag gtattgttta
     9601 ttgataccga tatgcgcaaa ggctatacgc ataaattgtt caatgaaaat aataccaatg
     9661 gtctctctga tattctgtca ggaaaagttg aaattaatag ggcattaaaa aaagtcgcat
     9721 caggtggttt tgatttcatt tcacggggaa tggctccacc aaacccggct gaattattaa
     9781 tgcacaggcg ctttggtgaa ttgctcaatt gggccagtga aaactacgat atcgttgttc
     9841 ttgatacgcc accaattctg gctgttactg atgctgcaat aattggtaat tatgtcggca
     9901 caactctact ggtagctcgt tttgaactaa acacagcaaa agaaattgaa gtaagtgtta
     9961 aacgattcga acaagccggt gtaacagtga aaggctgcat attgaatggt gttgtaaaaa
    10021 aagcaagtag ctattatggc tatggctata gtcattatgg atattcatat actgataagc
    10081 agtaaatttc aatgaggcag ggttttaaac cctgccttaa atttcatcct ttcgtgaata
    10141 tttaatcaga aattagatgc aatgcagaga gggtatatga cgcttctcgt cagaaatatt
    10201 attgtcagta ttgctttggc aatgtctgat ttttttagtt ttgttatttc attatattta
    10261 gcgatagggg ttttatcaat aacggtcggc gattatgaaa cagccgtttc agccaaccaa
    10321 cttgaagggt ggaaaatact ccactggttg ttagctcttt gctgtgttgc ctggtattct
    10381 atgaggctcc gccattattt ctaccgtaag acattttggt ttgaattaaa agagatattg
    10441 cgtactttag ttatttttgc tgtaattgag attgcagttt tggcatttgc aaattggtcc
    10501 ttttcaaggt ttttgtgggg actaacctgg gtttttgttc tgctgttggt gcctttggca
    10561 aggatggtaa ctaagcgtgt attggacgtg ttcggattat ggcatagaga aacatggata
    10621 ataggtagtg gggccaatgc acaggaagct tataaggcga taaatagcga gcgtaacctt
    10681 ggactggtta ttgtggggtt tgttgagaca gctaagggat tttcggaaaa taaaaatatc
    10741 gacggtatcc ctgtgcttgc gaatgatcct gattggttat cttcaatgga taaaaagact
    10801 cagtttattg tggccgttga atcgcaccag agtgaagtcc gtaatgcctg gttgcgtaat
    10861 tttatgatta aaggctatcg atatatctct gttattccaa cattgcgtgg gatgcctctc
    10921 gacagtacag atatgtcttt tatttttagt catgaagtga tgatatttcg ggttcaacaa
    10981 aaccttgcaa agtggtcctc aaggattctc aaacgcctct ttgatattgt tggctcaata
    11041 tcaataatcg ttattctttc tccagcattg atatatataa gccgtaaagt gaaaaaggat
    11101 ggtggacctg ctatttatgg acatgaacgc attggtaaag gtgggcaatc attcaagtgt
    11161 cttaagttcc gttcaatggt gataaattct aaagaagtcc ttgaaaattt attagaaaat
    11221 gatcctgaag caaaaaaaga atgggatgct acttttaaat taaaaaatga tcctcgaatt
    11281 acaaaaattg gaggattcct tcgtaggact agcctggatg aattaccgca gttattcaat
    11341 gtcctgaaag gcgagatgag tctggttgga cctaggccga tcattactgc tgaactagaa
    11401 cgatataatg aagaagtgga ttattatttg ctaagcaagc cagggatgac tggtctgtgg
    11461 caagttagtg gtcgtagtga tgttgattat gaaacaaggg tatacttgga tgcctggtat
    11521 gtgaaaaact ggtcaatgtg gaatgatatt gctattttat tcaaaactat tggtgtagtg
    11581 ctaaaaaaag atggagccta ttaaactggc aaaccaatta acttaacaca gggttgacat
    11641 gaaatatttt attgcaatac ctacctataa tggtggagat atttggcgag aggttgtctt
    11701 aaatattcag agacatgcac cagcaggatt acaggtgcag ataattgact cgagtagcaa
    11761 ggatgatacg gtaagtgtcg cgcgtaagga aggcttttct attgaatcta ttccaagtgt
    11821 agattttaac cacggaggaa cgcggaatat tgctgttagt aagcattcag atgaatgtga
    11881 tattgttata ttcttgacac aagatgcaat tcctgaggct ggttttatcg aaagaatcat
    11941 aagtgtattt gacgaccctc agattgcatg tgcttggggg cgtcagttgc ctcataatga
    12001 tgctaatcct atagctcaac atgcaaggta ttttaactat ccattggaaa gctatatttg
    12061 tagaaaagaa gatagctcaa ctttgggatt gaaaacggtg tttatgtcta actcattttc
    12121 tgcctatcgg ataaagacat tccaggaact aggcggcttc ccatcggata caattttatg
    12181 tgaagatatg tattatactg cgaaagcagt attggccggt tataaagtag cctatgtcgc
    12241 agatgctatt gtgcatcatt cacataatta ctcccccctg gaagagtttc ggaggtattt
    12301 cgacattggt gtgtttcatg ctgatgaacc ttggattcga aagcaatttg gtggtgcagg
    12361 cggtgaagga aaaagatttg tagtctccga attccgctat ctattaaaaa gtgacttgaa
    12421 atatattcct gtggcggttt taaataacgc aatgaaaata ctgggatata aacttggaca
    12481 gtggtacaaa tatttaccga agagatttat taaatttttt agcatgcata aacgcttctg
    12541 gaaattttaa gatatcattt tttaataaat catttaaatt ttattttgtt ctatttatgg
    12601 attaatagta ttttgagtga aaaacgtatg gtgatttttc tgatgattac gttatttttc
    12661 gcctgtagag gagatcttga tagctaatac cataatttca atcttttcat tgtgaacaat
    12721 tttgcagaaa gcatacttta tcaatgatgt gcatttataa gtaattaaaa aaaaatttat
    12781 aagtgaacaa aatgcattcc cttaaataaa agttataata attttattga ggtttcatgc
    12841 tataaatata tgcagcaaat gatttatttt aattttagat gagttctatt tttaaatcca
    12901 tattaattga aaaaagatga taccatgaaa aatatgctat atgtcactac agtttttgaa
    12961 gatgaaaatg atggtatttg gaagaaaata aagtatacac tctgtgcata tcagcgctta
    13021 ggatatttaa tagattttgc atatagaaca aaagcaggtt atgtaattaa ctttggattt
    13081 aatagcgaac aatctaaagt agaaagggtt aatgagcatc ataaggatct ctttttttac
    13141 aatttatcaa aaaaaataat aaaaaagtat gatttcttat atatacgaaa accttttgga
    13201 ggagctagct ttttattttt aaatttctta attagtaagg taaaaaaagg tggtgggaaa
    13261 gttgctttcg aaattccaac atatccatat agaaaagaaa ttaaaagtgt aaaaaatatt
    13321 atttctgaga gattatttca ggttagtaaa agtgcatatg tccataaaat agacttaatt
    13381 gtatatatgg gagagtctag tggtaacatt tgggggcggc cagcgctaaa aatagcgaat
    13441 ggtattgatt taaataaagt tcaaattctg aaagaaaact taaattctgt atcagatgag
    13501 tttatttttg tcggtgtggc gaggctctcc ttctggcatg ggtatgacag attaatcgaa
    13561 gcagtaaaaa attataaggg aaattataaa ataaaattta tagtcattgg taatggagaa
    13621 cctgagttat caagattgaa tgctcttact aaaaaacatg ctcttgaaga aaaagtatta
    13681 ttcttaggtg caaaatttgg taatgaatta gatatgcaat ataagaaagc acacgtatgc
    13741 attgattcaa ttgggaggca tcgtagtggt aaccaattta acagttctct taaatcaaaa
    13801 gaatatgctg cgaaagggct accatttatt atgagtcata aagatgattc ttttgaaaat
    13861 gtaaatttta ttttcaatgt aagtccagat gaagaaatga taaacatcga tgagatcatt
    13921 agttggtatg aaaaattacc tacaaacacc ccagttgaga tgagagcgtt tgctgagcaa
    13981 tttttatctt gggatattca atgcaaaaaa gtactagaaa atatcttcta ctaaagagtg
    14041 gttgagatga aaaaaattca agttttactt gctacttata atggctctaa atatgtcatt
    14101 gatcaaatca attctatact catgaatttt aaatgggtct ctgaatataa ttgtagtata
    14161 ttaatatctg acgattcatc atctgatgaa acaatccaat tgataaaaga taatttttct
    14221 aatattcctg gtgttaacat aatttcaacg tctcgaaaag gtggggttag aaataacttt
    14281 acatttttaa taaactacgc tgacggtgat ttcatattct tctgtgatca ggatgattta
    14341 tggttaccaa gtaaacttag agtatttatg gatgagttta atcaacgttc tgctctaaac
    14401 aacgaaccta tgcttattca ttctgatctt tgtgttactg attcaattct tagtccaatt
    14461 cacacatcaa tgtttgagta tcaaaaatta aataaagccc catcattttc taacatgatt
    14521 gttagtaact caattactgg ttgtgtttta ggtataaata aaagattgtt aaatatttta
    14581 aaaaaatcaa gtattaataa atctataatg catgattggt atatagggat aattgcatct
    14641 tccttcgggg aaataatcta tattccgaag tctttaattc tatataggca gcatgaaaat
    14701 aatcaagttg gggcgaagaa attttctttt tatgaaatgt tgagtttaga aaaaatacaa
    14761 aatattaaac aatccatttg gttgacaaaa gcacaagcag aattatttct ttcagatttt
    14821 gacgggcagt tagataaaaa taatgaaaaa atattgaaag cgtatatttc atcttttgat
    14881 agaaatattc tctcaaggtg tcttacgttt tttaagtatg ggttttataa atatggtttt
    14941 gctaggaata tagttttctt tatatttttt gttttttttg caggtgcaat aaaaaaacaa
    15001 aaaaatatta cataattatg ttgagggtaa atatgtttaa aactagatgt tatattaacc
    15061 taaggtcttt tttattacca ttcatagtat ttctacccac atgtgtgtta tctgcggaaa
    15121 atgtatcatc caataatatt gggcgtatcc tattgaagga tagcaattct attgataaaa
    15181 atgttctgtc aagtgtctac gcatcaaaag atacatatgg aatgagatct aatgcggttg
    15241 ttgccgcatt ttctgctaac cctgagaaac ctttcgattt tcctattctg gggtttagcg
    15301 gagttatgca aatggcaaaa tataaagata gagattccgt cagcctgtat gccgataata
    15361 cagctttgcc attcaaatca tgggaaaggg tgaaatctgc gaactatact gcaacgtcat
    15421 ttacaacaga ggaatcaaca gctttaaatt taaaacctgg aatgctagta gaaactggac
    15481 atgaaccaag ctggtcatca tatattatat caatagtggg gaataaagtt ataacatcag
    15541 gttgggttaa taactccact ggccatttag gtatacctaa ggatggatca ggattagtcg
    15601 ttaatcctat aactaaaata tgggctacta atttcaacat tttttttcct gaagggggga
    15661 gagcaaataa aggagttata caagaaaatg ggttaattaa taacaatatt gataatcctt
    15721 ccactatatc tgggcttgac acggtagttt tacctcagtc taagtttggg ggaacggctg
    15781 catatttagc tcgttcagct gattcaggtg gaaaacagca atggacttat ggttttttat
    15841 cttcaggctc aaaggttagt tttttgagtt ctgactcagg gattcattat ccagaaatta
    15901 gttttcatga ttcgtcttct gcaaataatg gacttgtatt tgatggaaag aataagtcta
    15961 attctatcct ttggaaggac ggtaataata acataaccgc gaaaatagat cctactggta
    16021 gaatatcgat gattggatat aaaacaagag aaataaaaga tagttctaaa ttaactacag
    16081 atttctccag atatattgtt gaaaataata gtgaaataaa tttaattttg cctgatagta
    16141 aaaatattat cgacggcttt actttaaaaa tagttaaagt agggggggag agctcaatcg
    16201 tcaatattcg cacaccagat aatgtaagta taaatggaga aatgaaagtg cttagtttat
    16261 ctggccgatg gaataaggaa gttatttatt ataataagca atggtttttt tactgaagct
    16321 tttctagtgt agtatactgc tcatatttca aatttaataa tagggatttt aattatgcct
    16381 tatttttttt atagctctac actttttcta tattttataa tatctttatt cctactttct
    16441 ctgtccgtag ctagtatact tgttaaaagc aagaaaatgg atagtgtcgt tttcattcta
    16501 atatctataa tgatgatttg cttctatggg tttaggttcc ctggaacagt cgatataaag
    16561 atgtatttgc agaatttcga tgcattatca agttttcaag atttccaatg ggggatcggt
    16621 ttttatatgt taatgaaatc gatcaaaata tttgatgcat cacatacagc gtatgttttt
    16681 tatagcgctc tttattttgt tatcgctttt gtagctgtgg gcttttttta ttgtaaaggg
    16741 aaatattata aatcactatt tttaatttct agtttttata gttggagtat tttagatctt
    16801 gctgttaata catataggca aggtatcgct gttcctttta ttttactggg tttgtatttt
    16861 ttgactcaaa gaaagtatat tttatcttcg atagttattt gcgtttcgct aactttgcac
    16921 tggggaagtg cagttatact tttgctttac atttttgcta tttacttatc taaaagaatt
    16981 tttttactta agatagtgtc ttttttaact ttaactttat ttactatctc atttttcgta
    17041 aattttagta ttgcggagat gttatcaacg agttctattc tcagtatatt gcaggttatt
    17101 tttgttgggg ttgactttga ttctaaagtt aatgcttatt taggtggggg agttctaggc
    17161 gcgaattttt atgatatgaa tagtcttcag cgtctttatt tttcaggtga aatttatata
    17221 tccttgcttg tctttgtttt tttcttcatg acaaggaaaa ggaacgatta catctttaca
    17281 aataaaaaaa ataatttctt gcttatttat tcgtttttta tatcggtatc attgtatggt
    17341 gttatattga tatcaatgac atggtttatc agaaactttt actgggtggt tcccgttgcc
    17401 cccattttat atgttatgat tttagagtat tatgagtcat ctaatcctaa aaaatttaaa
    17461 atattactat tattatttgt tttattttca ataacatatt cattggaaac attctggcga
    17521 acccctttga ttgatatgtc ttacccatca gtttcaatat aaaagataag ttttttgatc
    17581 attgcgctag atattagcgc gtttctgtga atttaaagaa acatgttcag gttatactga
    17641 tttttacacg taataaatta aatttaaatt attgctaata agtcgtagta tcaattttcc
    17701 atattaagcg attacagaag attatatatt aaaaccactc tgaatatcaa atgtcataaa
    17761 ttatgaaaat aggaattaag gtattaattg cttattaacg ctatggggta tatatataat
    17821 gtcgttgaaa gaaaaaactt tgaatgcggt aaaatggaat ttactttcaa caatagtaac
    17881 agtgtcttta ggtatggttt ctctttgggc tttatctcat attcttagcg ttgaacagta
    17941 tggggttata agtgccgctc ttatcattac taattttatt aatatgctat tggattttgg
    18001 gatttcaaac tccattgtgc gtagtcaaac agttgaaaga attgaattag cgtctttatc
    18061 tgttgtaaat atttttatgg gtatagccgc ttttatattg acttttattt ttagcgaaaa
    18121 tattgcaggg gtatttggag gttcagaaaa cttaagattc caggtggaga tagtatcatt
    18181 tggttttata tttattgcat tgggtttaca gccaaaagct ttattgacta aagatatgga
    18241 atttggtttg ctatccaaga tcgttattat agtggcaata acgaatttta ttattgcagt
    18301 gactttagct tttatattcc acgaagcgtg gtgtgttgct gtagcatttt tagtaagttc
    18361 tataattggt tctttaattg ccagattttg tgctagaaaa ctgatggatt atggagcagg
    18421 gtttcaacta aaggcaataa gaaaacactt tcggtatggt attcagcttg ttattgactc
    18481 attaattaat caaataagta ttaatactta tcccgtgttg atgtcgcgtc ttataagttt
    18541 tgctgcgata ggtggttata atatttctta cagtataagt attgcattat ttgagagact
    18601 taaccctatt ctttcccatg cacttttccc tgcattttca aaaataggta atgatgaaaa
    18661 gaaattacaa tcatcgtttc ttaaagtgac tattttttcc tcaatggtca attttccaat
    18721 gttaatcggc atgatgcttg cttctacaca aattgttaga atcttttttg atgaaaagtg
    18781 gtcatttatt ccacctattg tgcaaattct ttgtattgtt ggcgttctcc gctctttaga
    18841 gactcctgtt atatctgtat tgctagttaa ggctcaaatg tatcgcaata tttatctggg
    18901 tattgggaaa ttattgactg gaatcccatt ggcttggttt ttgggaactc gttttggaat
    18961 aacaggaatt gtatatggat ttttgatcat tcaggtggta aatacaacgc taggatattt
    19021 ttatctgtta aagcctagtt taggaatttc tggattaaaa tatcttaaaa gtattctaat
    19081 acctgcaatt catgttctac caatggtagt agggggctta atcttaaata aaatggaact
    19141 aatagataat caatttgctc atttatttat tctgattgca ctctgttttg ttttatactc
    19201 ggttaccatc tttatgtcac ccgttgatat tgtcagagag tttagggcga ctattattaa
    19261 taattttatg actaaggctt taaagaaatg aaattatcaa ttattatccc ctgttataat
    19321 tgtgctggca gaattaataa attattaacg ctaatatatc aacaggttaa agataatgat
    19381 aatgttgagg tggttttagt taatgatggt tcaactgata atactaggaa tgttatttct
    19441 gattttttgc agaataatgt atcagatgaa tttatactga ttaatacaga gaatagaggt
    19501 gctgctggtg ccagagaaaa ggctctcgaa tttgctacgg gtgaatatat tttcttttgt
    19561 gattcagatg atttgattgc gcataacttt gttcaaacga tattaagtgg ctgtgagtca
    19621 tgcccagatg ttatttattt tagctctgag atgatctcta gtggtgaaga ttattataaa
    19681 attgctgaca aggttttatt caaagataac actgttttta cttcaccgga tgaatttttg
    19741 ttttatcagt taaagcgtgg atattggact gctgctgtat ggacttatgt attcaggaga
    19801 aatattgctg ttttacagca tgcaactttt tctgctcgaa gagcacacga ggaccatctg
    19861 tttactgcta aggttgtttt aagtgcaaat aaaataattt gcttaaaaga tgttttatat
    19921 tttcaggttt taacaatagg atctttaact aattctaaaa aaaacttaga ctatatttct
    19981 gaaaggtatt tggcatttgt tgagaccaga tattatttaa aagaaaaatg taaaaaagag
    20041 acagtcttgc tttatgaaac ttggacccta agatcaataa tatctttgtt tttagagaat
    20101 aaaaatcttc ttttaaatgc cttgctatct ttttctgtat ggaagtctgt ttttacagag
    20161 aaagtgctaa tatgtaaatt tttattttgt ttcttaaaaa agaaagtgaa atatggtgca
    20221 aacaaaaatg actgaatcta aaagtatcat tttaaattta acaacaacaa gtggacgatt
    20281 agatctatgt tctgccacac tttggtcttt agttaatcaa tcattactcc cgggaagaat
    20341 taatttatgg atatcagcag agccatatat ggctgatgaa ggtattcaga tactacctga
    20401 ttcaattaat agattgataa agtataatga cataattaaa gttcattatg ttgagaatac
    20461 agggccttat cgtaaaataa ttcctgcact gaggagttgt ttagatgaag atatattagt
    20521 ttatgctgat gatgatgttg tatattctca tcattggctt gagtatctta taagttttta
    20581 tctggagaat aatagagagt atgttgtttc tagtcgacta agagaaatga aaaagaattt
    20641 cttcggactt taccaaagtt acagcctctt tccattagtt tttgaaaaaa aagtttttta
    20701 tacagatttt attattactg gtgttggtgg ttgtgttctt gagagaaaac atatatcaca
    20761 aaaatatatt gatctgaatt catttaaaaa aatagcccca aagacggatg atctatggat
    20821 tagcaaaatt attgaactat ctggaagcgg agttattgcc tgccctaagg cgttagactg
    20881 cataatggaa attcagcatg acatacatgc tttaaatagg atgaatacat tctttagcag
    20941 ccaaaatata atttccaaaa tgataggggc tttcaaaaga agattgttgg gttattgtgg
    21001 tgtgtcattg tcaaataatg atgtcatgat aaaaacaata aattctttct ttaagagaaa
    21061 tatttagcaa gtcattaatg acgtttaaac tacttgttga tgacttaaag catcatcaat
    21121 ttattatatt gagttggttt ttatattttt cttactgaga aacaatgcag gtatattaaa
    21181 gtgatagtat gtcggattga ttatttcgca tattttatct aatttggctc gtgcatatag
    21241 ttcttttgct tatgtacata agtttaagac ttaatcagga atcaatgctt ttcattagtc
    21301 ttttatcatg cttatttatt tcgactaggc gacgcaacag ctttgagcta acataaccac
    21361 tacatttaag ctgcgagcgt gtcgcagtga gcacacctga caggagtatg taatgtccaa
    21421 gcaacagatc ggggttgtcg gtatggcagt gatggggcgc aaccttgcgc tcaacatcga
    21481 aagccgtggt tataccgtct ctgttttcaa ccgctcccgt gaaaagaccg aagaagtgag
    21541 tgccgaaaat ccaggcaaga aactggtccc gtactatacc gtgcaagagt ttgttgaatc
    21601 cctcgaaact ccacgccgca tcctgttaat ggtgaaagcg ggcgcaggta ccgacagcgc
    21661 tatcgattcc cttaagccgt atctggataa aggcgacatc atcatcgatg gtggtaacac
    21721 cttcttccag gacactatcc ggcgtaaccg tgagctgtct gccgaaggtt tcaactttat
    21781 cggtaccggt gtttctggtg gtgaagaggg tgcactgaaa ggcccgtcta tcatgcctgg
    21841 tgggcagaaa gaagcctatg agctggtagc gccaattctc gagcagattg ctgctcgtgc
    21901 tgaagatggt gaaccatgtg tcgcctatat cggtgctgac ggtgcgggtc actatgttaa
    21961 aatggtccac aacggtatcg aatatggcga catgcagctg attgccgaag cttatgcgtt
    22021 actgaaaggt ggtctggcgc tttctaatga agaactggcg acaaccttta ccgaatggaa
    22081 cacaggtgag ctcagcagct atctgattga tatcaccaaa gacatcttca ctaaaaaaga
    22141 tgaagaaggt aaatatctgg ttgatgtcat tcttgatgaa gcagccaaca aaggtaccgg
    22201 taaatggacc agccagagtt cactggatct gggcgaaccg ctgtccctga ttaccgagtc
    22261 cgttttcgct cgttatatct cttctttgaa agatcagcgt gttgctgctt ctaaagtcct
    22321 gacggggcca gaagctcaac cagcaggtga caaggctgag tttgtagaga aagttcgccg
    22381 cgctttatat ctgggcaaga tcgtttctta tgctcaaggc ttctcccaat tgcgtgctgc
    22441 atctgacgaa taccactggg atctgaacta cggtgagatt gccaaaatct tccgtgccgg
    22501 ttgtatcatt cgtgcgcagt tcctgcagaa gatcactgat gcttacgagc agaatgcaag
    22561 cattgctaac ctgctgctgg cgccgtactt caaacagatt gccgatgaat atcagcaggc
    22621 actgcgcgat gtcgtggctt atgccgttca gaacggtatc ccggttccga cattctctgc
    22681 tgccattgcc tactacgaca gctaccgctc tgcagtcctg ccggctaacc tgatccaggc
    22741 tcagcgcgac tatttcggtg ctcataccta taaacgcact gataaagaag gtgtattcca
    22801 taccgagtgg atggaataat tccattctgc tttaatcctg ggggaatacc ccaggatttt
    22861 ctgattatta ttctataaac ataagcgttc ccttatattt tagcgttaag tgttagtaat
    22921 tttataattt gattatactc tcttctgaat atatttcttg atgcagcagt ctgagtaagg
    22981 ctagtgtgtt aaatttaata tactgagctt ttataactat taatttgaag tctgtattta
    23041 acattaaagg tagattaaat atgaagatcc ttgtcactgg cggcgcgggt tttattggtt
    23101 ctgcagttgt tcgtcatatt attgaaaata cccaggacga agtacgcgtg atggattgcc
    23161 tgacttatgc ggggaatctt gaatctctgg cgacggttac cgacagcgaa cgttactcct
    23221 ttactcaaac tgatatcacc gatgctaaat ccgtctcgga gcagctcagc gatttccgtc
    23281 cggatatcgt gatgcacctg gcggcagaaa gccatgtcga ccgctcaatt gatggtccgg
    23341 cagcctttat tcagactaac ctgatcggca cctttaccct gctggaggcg gcacgtcact
    23401 attactctac cctggatgcc gcgcagaagc aggcgttccg tttccaccat atctctactg
    23461 atgaagttta tggtgacctg cacggcactg atgacctgtt tacggaagaa acgccgtatg
    23521 cgccaagcag cccttactct gcctccaagg ccggtagcga tcatctggtt cgtgcctgga
    23581 accgtaccta cggtctgccg gtcgtggtga ccaactgctc taataactat ggcccgtatc
    23641 acttcccgga aaaactgatc ccgctgacca ttctcaatgc gctggcaggt aaaccgctgc
    23701 cggtgtatgg caacggcgaa cagattcgtg actggctcta tgtggaagat cacgcgcgtg
    23761 cgctctataa agtcgccacc gaaggtgaga gcggtgaaac ttataacatt ggcggccata
    23821 acgaacgtaa gaatattgat gtagtacgta ctatctgcgc cattctcgat aaagtcgtag
    23881 aacagaagcc gggcaacatc agccagtttg ccgatctcat cacctttgtg aaagatcgtc
    23941 cgggtcatga tctgcgttac gcgattgatg cagcaaaaat tcagcgcgac ctgggctggg
    24001 tcccgcaaga aacttttgaa agtggaattg aaaaaacggt tcactggtat ctgaacaatc
    24061 agaactggtg gcagcgtgtg ctggacggct cctatgccgg tgaacgtctt ggtctgaata
    24121 actaattgtc ctggcttggc tcactcatta aggaaactga caaatgaaag gtattgttct
    24181 ggccggtggc tccggtacgc gtctgtaccc gattacccag ggtgtctcta aacagcttct
    24241 gccgatttac gataagccga tgatttatta tccggtgtct gtgctgatgt tatcggggat
    24301 ccgcgatatt ctgatcatca ccacgccgga agatatgcca gccttccagc gtctgctggg
    24361 cgatggttct cagtttgggg ttaacttcag ctacgccatt cagccgtatc aggatggtct
    24421 ggcgcaggcc tttattatcg gtgagaaatt tatcggtaat gatgcctgtg cgttagtact
    24481 gggtgacaat atttatttcg gtcagagttt tggtaaaaaa ctggaagccg ctgccagcaa
    24541 aacatcgggc gccaccgtgt ttggctatca ggtgctcgat ccggaacgtt ttggtgtggt
    24601 ggagtttgat gaaaacttcc gcgccttgtc gattgaagaa aagccgctaa aaccaaaatc
    24661 agactgggca gtcaccgggc tctatttcta cgacaacaac gtggtggaaa tggcgaaaga
    24721 ggtgaagccg tctgagcgtg gcgagctgga aatcaccacc ctgaaccaga tgtatctgga
    24781 tcgtggcgac ctgcaggttg aactgctggg ccgtggtttt gcctggctcg ataccggtac
    24841 tcatgacagc cttattgagg cttcgcagtt cattcacact attgagaagc gccagggcat
    24901 gaaagtggcc tgtctggaag agattgccta ccgcaatgac tggctgagcg ccgaaggggt
    24961 tgcggcacag gcagaacggt tgaagaaaac cgaatatggc gcttatctca aacgcctgct
    25021 aaacgaacgt taatcgcctg ccgatcgcat acagggtatt caataatgaa aattttactg
    25081 attggtaaaa acggccaggt tggctgggag ctgcagcgtt cgctgtcgac gctgggtgag
    25141 gtggtcgccg ttgattattt cgataaagaa ttatgcggtg atttaacgaa tcttgaaggc
    25201 attgcgcaaa ctgttcgtca ggtaaagccg gacgtcattg tcaatgcggc ggcccacacc
    25261 gcggtagata aagctgaaag cgagcgtgaa ctgtctgacc tgctgaatga taagggcgtg
    25321 gcggtgctgg cggaagagtc ggcaaaactg ggggcgctga tggtccacta ctctaccgac
    25381 tatgtgtttg acggtctggg tagccattat cgccaggaag atgaggccac cgggccgctc
    25441 aatgtctatg gcgaaaccaa acgtgccgga gaaattgcgc tggagcaggg gaatccccgt
    25501 catctgatct tccgcaccag ttgggtctat gcaacgcgtg gggcgaactt tgccaaaacc
    25561 atgctgcgcc tggccgctga aaaagagacg ctgtcgatca ttaatgacca gcacggcgca
    25621 ccgaccgggg cagagctgct ggcggactgc actgccatcg ccatccgtga agagttgcgt
    25681 aataaagcgg ttgccggaac ctaccatctg gtcgccagcg gcgaaacgag ctggtatgac
    25741 tatgcccgct ttgtttttga cgtggcacga gctaacggcg tgcagctggc tatcaatgag
    25801 gttaacggga tcccgacaac ggcctatcca acaccggcaa aacgtccgct gaattcccgc
    25861 ctgtcgaatg agaaattcca gcgcgtattt ggtgtcacgc tcccggactg gcgtcagggt
    25921 gtagagcgcg tggtcgttga agtttcaggc aagtaagggc atacaaaatg aatattatta
    25981 aaacagacat tcctgacgta ctgattttcg aacctcgcgt gttcggcgat gcgcgtggtt
    26041 ttttcttcga aagcttcagc agcaaggtgt ttgacgaggc ggtcggtcgt catgttgagt
    26101 ttgtgcagga caaccactcg cagtcgcaga agggcgtgct gcgcggtctg cactaccagt
    26161 tggatccgca ctcacagggc aaactggtgc gctgcgtgga aggtgaggtt tttgatgtgg
    26221 cggtggatat ccgtcgttca tcgccaacct ttggccagtg ggtcggggcg gtgctgagtg
    26281 cggaaaacaa acgtcagctg tggatcccgg aagggtttgc gcatggattt atggcgctga
    26341 gcgagacggt acagtttgtc tataaagcga ctaactacta cgcgccacag tcagagcgta
    26401 gcattctctg gaatgacccg gatattggta ttaactggcc tgaactggac ggctgcacgc
    26461 tttctttgtc agagaaagat atgcaggccc atactctggc aaccgctgaa gtgtataaat
    26521 aaatattcta ttgatgatta tttatacttc ctgaaaggcc cgatcagggc ctttttaata
    26581 gcgccatttt gtgcctttct tgacacttat cttctcaaag agtacaaccg ccagaagtat
    26641 tgattacagg gtggctacta tgccgccgtc cagttaactg attaaagtgt gatcgaatga
    26701 aaattactat ttccggtacc ggttatgttg gtttatcgaa cggcatcctg attgcgcaga
    26761 accacgaagt ggtcgcgctg gatatcgtac aatctaaagt tgatatgctg aaccagaaga
    26821 tatcgccgat tgtcgataaa gagattcagg aatatctggc cgaaaaaccg ctgaattttc
    26881 gtgcgacaac tgacaagcaa gatgcatatc gcaatgctga ctatgtcatt atcgccacac
    26941 cgactgacta cgatccgaag accaactact
//
