LOCUS       EU038216               10837 bp    DNA     linear   BCT 11-JUN-2008
DEFINITION  Neisseria meningitidis strain 2003-240 CtrD (ctrD), CtrC (ctrC),
            CtrB (ctrB), CtrA (ctrA), GlcNAc-6-P epimerase (siaA), CMP-NeuNAc
            synthetase (siaB), Neu-NAC synthetase (siaC), and
            polysialyltransferase (siaD) genes, complete cds.
ACCESSION   EU038216
VERSION     EU038216.1
KEYWORDS    .
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 10837)
  AUTHORS   Tsang,R.S., Tsai,C.M., Henderson,A.M., Tyler,S., Law,D.K.,
            Zollinger,W. and Jamieson,F.
  TITLE     Immunochemical studies and genetic background of two Neisseria
            meningitidis isolates expressing unusual capsule polysaccharide
            antigens with specificities of both serogroup Y and W135
  JOURNAL   Can. J. Microbiol. 54 (3), 229-234 (2008)
   PUBMED   18388994
REFERENCE   2  (bases 1 to 10837)
  AUTHORS   Tsang,R., Tsai,C.M., Henderson,A., Tyler,S., Law,D., Zollinger,W.
            and Jamieson,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JUL-2007) Public Health Agency of Canada, National
            Microbiology Laboratory, 1015 Arlington St., Winnipeg, Manitoba R3E
            3R2, Canada
FEATURES             Location/Qualifiers
     source          1..10837
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /strain="2003-240"
                     /db_xref="taxon:487"
     gene            complement(1..651)
                     /gene="ctrD"
     CDS             complement(1..651)
                     /gene="ctrD"
                     /codon_start=1
                     /transl_table=11
                     /product="CtrD"
                     /protein_id="ABW08132.1"
                     /translation="MISVEHVSKRYLTRQGWRTVLHDISFKMEKGEKIGILGRNGAGK
                     STLIRLISGVEPPTTGEIKRTMSISWPLAFSGAFQGSLTGMDNLRFICRIYNVDIDYV
                     KNFTEEFSELGQYLYEPVKRYSSGMKARLAFALSLAVEFDCYLIDEVIAVGDSRFADK
                     CKYELFEKRKDRSIILVSHSHSAMKQYCDNAMVLEKGHMHQFEDMDKAYEYYNSLP"
     gene            complement(648..1445)
                     /gene="ctrC"
     CDS             complement(648..1445)
                     /gene="ctrC"
                     /codon_start=1
                     /transl_table=11
                     /product="CtrC"
                     /protein_id="ABW08133.1"
                     /translation="MKALHKTSFWESLAIQRRVIGALLMREIITRYGRNNIGFLWLFV
                     EPLLMTFVIVLMWKFLRADRYSTLNIVAFAITGYPMLMMWRNASKRAVGSISSNASLL
                     YHRNVRVLDTILARMILEIAGATIAQIVIMAVLIAIGWIEMPADMFYMLMAWLLMAFF
                     AIGLGLVICSIAFNFEPFGKIWGTLTFVMMPLSGAFFFVHNLPPKVQEYALMIPMVHG
                     TEMFRAGYFGSDVITYENPWYIVLCNLVLLLFGLAMVSKFSKGVEPQ"
     gene            complement(1445..2608)
                     /gene="ctrB"
     CDS             complement(1445..2608)
                     /gene="ctrB"
                     /codon_start=1
                     /transl_table=11
                     /product="CtrB"
                     /protein_id="ABW08134.1"
                     /translation="MSEQLPVAVATETKAERKKPKKKSWIKKLSPLFWVTVIIPTVIS
                     LVYFGFFASDRFTSQSSFVVRSPKSQSSLNGLGAILQGTGFARAQDDIYTVGEYMRSR
                     SSLDELRKILPVREFYETKGDAFSRFNGFGFRGEEEAFYQYYKNQVMINFDTVSGIST
                     LNVTSFDALESKKINEALLKQGEALINQLNDRARADTVRYAEEVVKTAAERVKEASQN
                     LTDYRIANGVFDLKAQSEVQMGLVSKLQDELIVIQTQLDQVKAVTPENPQIPGLQARE
                     QSLRKEIDQQLRAISGGGHSSLSNQAAEYQRVYLENQLAEQQLAAAMTSLESAKVEAD
                     RQQLYLEVISQPSLPDLAHEPKRLYNIVATLIIGLMVYGILSLLTASIREHKN"
     gene            complement(2623..3798)
                     /gene="ctrA"
     CDS             complement(2623..3798)
                     /gene="ctrA"
                     /codon_start=1
                     /transl_table=11
                     /product="CtrA"
                     /protein_id="ABW08135.1"
                     /translation="MFKVKFYIRHAVLLLCGSLIVGCSAIPSSGPSAKKIVSLGQQSE
                     VQIPEVELIDVNHTVAQLLYKAQINQSFTQFGDGYASAGTLNIGDVLDIMIWEAPPAV
                     LFGGGLSSMGSGSAHQTKLPEQLVTARGTVSVPFVGDISVVGKTPGQVQEIIKGRLKK
                     MANQPQVMVRLVQNNAANVSVIRAGNSVRMPLTAAGERVLDAVAAVGGSTANVQDTNV
                     QLTRGNVVRTVALEDLVANPRQNILLRRGDVVTMITNPYTFTSMGAVGRTQEIGFSAR
                     GLSLSEAIGRMGGLQDRRSDARGVFVFRYTPLVELPAERQDKWIAQGYGSEAEIPTVY
                     RVNMADAHSLFSMQRFPVKNKDVLYVSNAPLAEVQKFLSFVFSPVTSGANSINNLTN"
     gene            3933..5066
                     /gene="siaA"
     CDS             3933..5066
                     /gene="siaA"
                     /codon_start=1
                     /transl_table=11
                     /product="GlcNAc-6-P epimerase"
                     /protein_id="ABW08136.1"
                     /translation="MKRILCITGTRADFGKLKPLLAYIENHPDLELHLIVTGMHMMKT
                     YGRTYKEVTRENYQHTYLFSNQIQGEPMGAVLGNTITFISRLSDEIEPDMVMIHGDRL
                     EALAGAAVGALSSRLVCHIEGGELSGTVDDSIRHSISKLSHIHLVANEQAVTRLVQMG
                     EKRKHIHIIGSPDLDVMASSTLPSLEEVKEYYGLPYENYGISMFHPVTTEAHLMPQYA
                     AQYFKALELSGQNIISIYPNNDTGTESILQELLKYQSDKFIAFPSIRFEYFLVLLKHA
                     KFMVGNSSAGIREAPLYGVPSIDVGTRQSNRHMGKSIIHTDYETKNIFDAIQQACSLG
                     KFEADDTFNGGDTRTSTERFAEVINNPETWNVSAQKRFIDLNL"
     gene            5070..5756
                     /gene="siaB"
     CDS             5070..5756
                     /gene="siaB"
                     /codon_start=1
                     /transl_table=11
                     /product="CMP-NeuNAc synthetase"
                     /protein_id="ABW08137.1"
                     /translation="MEKQNIAVILARQNSKGLPLKNLRKMNGISLLGHTINAAISSKC
                     FDRIIVSTDGGLIAEEAKNFGVEVVLRPAELASDTASSISGVIHALETIGSNSGTVTL
                     LQPTSPLRTGAHIREAFSLFDEKIKGSVVSACPMEHHPLKTLLQINNGEYAPMRHLSD
                     LEQPRQQLPQAFRPNGAIYINDTASLIANNCFFIAPTKLYIMSHQDSIDIDTELDLQQ
                     AENILNHKES"
     gene            5757..6806
                     /gene="siaC"
     CDS             5757..6806
                     /gene="siaC"
                     /codon_start=1
                     /transl_table=11
                     /product="Neu-NAC synthetase"
                     /protein_id="ABW08139.1"
                     /translation="MQNNNEFKIGNRSVGYNHEPLIICEIGINHEGSLKTAFEMVDAA
                     YNAGAEVVKHQTHIVEDEMSDEAKQVIPGNADVSIYEIMERCALNEEDEIKLKEYVES
                     KGMIFISTPFSRAAALRLQRMDIPAYKIGSGECNNYPLIKLVASFGKPIILSTGMNSI
                     ESIKKSVEIIREAGVPYALLHCTNIYPTPYEDVRLGGMNDLSEAFPDAIIGLSDHTLD
                     NYACLGAVALGGSILERHFTDRMDRPGPDIVCSMNPDTFKELKQGAHALKLARGGKKD
                     TIIAGEKPTKDFAFASVVADKDIKKGELLSGDNLWVKRPGNGDFSVNEYETLFGKVAA
                     CNIRKGAQIKKTDIS"
     gene            6958..10071
                     /gene="siaD"
     CDS             6958..10071
                     /gene="siaD"
                     /codon_start=1
                     /transl_table=11
                     /product="polysialyltransferase"
                     /protein_id="ABW08138.1"
                     /translation="MAVIIFVNGIRAVNGLVKSSINTANAFAEEGLDVHLINFVGNIT
                     GAEHLSPPFHLHPNVKTSSIIDLFNDIPENVSCRNIPFYSIHQQFFKAEYSAHYKHVL
                     MKIESLLSEEDSIIFTHPLQLEMYRLANNNIKSKAKLIVQIHGNYMEEIHNYEILARN
                     IDYVDYLQTVSDEMLEEMHSHFKIKKDKLVFIPNITYPISLEKKEADFFIKDNEDIDN
                     AQKFKRISIVGSIQPRKNQLDAIKIINKIKNENYILQIYGKSINKDYFELIKKYIKDN
                     KLQNRILFKGESSEQEIYENTDILIMTSQSEGFSYIFLEGMVYDIPILAYNFKYGAND
                     FSNYNENASVFKTGDISGMAKKIIELLNNPEKYKELVQYNHNRFLKEYAKDVVMAKYF
                     TILPRSFNNVSLSSAFSRKELDEFQNITFSIEDSNDLAHIWNFELTNPAQNMNFFALV
                     GKRKFPMDAHIQGTQCTIKIAHKKTGNLLSLLLKKRNQLNLSRGYTLIAEDNSYEKYI
                     GAISNKGNFEIIANKKNSLVTINKSTLELHEIPHELHQNKLLIALPNMQTPLKITDDN
                     LIPIQASIKLEKIGNTYYPCFLPSGIFNNICLDYGEESKIINFSKYSYKYIYDSIRHI
                     EQHTDISDIIVCNVYSWELIRASVIESLMEFTGKWEKHFQTSPKIDYRFDHEGKRSMD
                     DVFSEETFIMEFPRKNGIDKKTAAFQNIPNSIVMEYPQTNGYSMRSHSLKSNVVAAKH
                     FLEKLNKIKVDIKFKKHDLANIKKMNRIIYEHLGININIEAFLKPRLEKFKREEKYFH
                     DFFKRNNFKEVIFPSTYWNPGIICAAHKQGIKVSDIQYAAITPYHPAYFKSPKSHYVA
                     DKLFLWSEYWNHELLPNPTREIGSGAAYWYALDDVRFSEKLNYDYIFLSQSRISSRLL
                     SFAIEFALKNPQLQLLFSKHPDENIDLKNRIIPDNLIISTESSIQGINESRVAVGVYS
                     TSLFEALACGKQTFVVKYPGYEIMSNEIDSGLFFAVETPEEMLEKTSPNWVAVADIEN
                     QFFGQEK"
ORIGIN      
        1 ttaaggcagc gaattataat attcgtaggc tttgtccata tcttcaaact ggtgcatatg
       61 ccctttttcc agcaccatcg cattatcgca atattgcttc atggcgctgt ggctgtgcga
      121 caccaagatg atggaacggt ctttgcgctt ttcaaacaac tcgtacttac atttatcggc
      181 aaagcgcgag tcgccaactg caatcacttc gtcaatcaga tagcaatcaa actctaccgc
      241 caacgacaaa gcaaatgcca aacgcgcctt catacctgaa gaataacgct tgaccggctc
      301 gtaaagatat tgccccaact cggaaaactc ttcggtaaag ttcttcacat aatcgatatc
      361 gacattgtaa atccggcaga tgaaacgcaa attgtccata ccggtcagac tgccttgaaa
      421 cgcaccggag aatgccaaag gccaagaaat actcattgtc cgcttgattt cacccgtggt
      481 cggcggctca acgccactga tcaaacggat gagcgtcgat ttacctgcac cgttgcggcc
      541 gagaataccg attttctcgc ccttctccat tttgaagcta atatcgtgca agactgtccg
      601 ccaaccttgg cgggtcagat agcgtttgga aacgtgttca actgaaatca ttgcggctcg
      661 actcctttac tgaatttact gaccatcgcc aagccaaaca acaacaacac cagattgcac
      721 aatacgatat accaaggatt ttcataggta attacatcgc tgccaaaata tccggcacgg
      781 aacatttctg tgccatgcac catcggaatc attaatgcat attcttgtac cttgggcggc
      841 aaattatgca caaaaaagaa cgcaccggat aacggcatca tcacaaaagt caatgtgccc
      901 caaatcttgc caaacggctc gaaattaaag gcaatcgaac aaatcaccaa acccaaacca
      961 atcgcaaaaa aagccatcaa aagccaagcc atcagcatat aaaacatatc tgccggcatt
     1021 tcaatccagc caatcgcaat caataccgcc ataatcacaa tctgcgcaat ggttgcacca
     1081 gcaatttcca aaatcatgcg cgccaagatg gtatccaaaa ctcttacatt gcggtgataa
     1141 agcaagctgg catttgaaga aatcgaccca actgcccgtt ttgaggcatt acgccacatc
     1201 atcaacatcg gatagccagt aatcgcaaat gcgacaatat tcaaagttga atatcggtct
     1261 gcccttaaaa atttccacat caagacgata acgaatgtca tcagcaacgg ctcaacaaac
     1321 agccataaaa agccaatatt attgcgaccg taacgggtga taatttcccg catcaacagc
     1381 gcaccgatta cgcgcctttg aatggctaaa gattcccaaa atgatgtttt atgcaaggct
     1441 ttcatcagtt tttatgctca cgaatgctgg cagtcaacag gctcaaaata ccataaacca
     1501 tcaagccgat aatcagagtg gcaacaatgt tgtataaccg tttaggctca tgtgccaaat
     1561 ccggcaggct cggttgcgag atcacttcca aataaagctg ctgacggtct gcttcaacct
     1621 tggcactttc caaagaagtc atggcggctg ccaactgctg ctctgccaac tggttttcca
     1681 aatacacacg ctgatattcg gcagcctgat tagacaacga agaatgccca ccgcccgaaa
     1741 tggcacgtaa ctgttggtca atttctttac gcaagctctg ctcacgcgcc tgcaaacccg
     1801 gaatctgcgg attctccgga gtgactgctt tcacctgatc cagctgggtt tgaatcacaa
     1861 tcaattcatc ttgcagcttg gaaaccaacc ccatttgcac ttccgattgc gctttcaaat
     1921 caaaaacgcc attggcaatc cggtaatccg tcagattctg agaggcttcc tttacccgct
     1981 ctgccgccgt tttcactact tcttccgcat agcgcaccgt atcagcacgt gcacgatcgt
     2041 tcaactggtt aatcaatgct tcaccttgtt ttaacaaagc ctcattgatt ttcttagatt
     2101 ccagcgcatc aaaggaagtt acattcaacg tggaaatacc cgaaaccgta tcaaaattga
     2161 tcatcacctg atttttatag tattgataaa aagcctcttc ctcgccacgg aacccaaacc
     2221 cattaaagcg gctgaacgca tcacctttgg tttcataaaa ctcacgcacc ggcaagattt
     2281 tacgcagttc atccaaagac gagcgcgaac gcatatactc cccaaccgtg taaatatcat
     2341 cttgcgcacg ggcaaaacct gtgccctgca aaatggcacc caggccattg agagaagatt
     2401 ggcttttagg cgagcgcacc acaaagctcg attgcgacgt aaaacgatcg gaagcgaaga
     2461 agccgaaata caccaacgaa attaccgtag ggataatcac cgttacccaa aataaagggc
     2521 ttagcttttt aatccaactt ttctttttcg gctttttacg ctcggctttg gtttcagtgg
     2581 caactgccac aggaagttgc tcagacatct taattactca cattaattag ttaaattatt
     2641 aatactgttc gcgccactgg taaccggcga gaacacaaac gacaaaaatt tctgcacttc
     2701 agccaacggc gcattcgaca catacaatac atctttattc ttcacaggaa agcgctgcat
     2761 agaaaatagc gaatgcgcat cagccatatt cacacgatat accgttggaa tctctgcctc
     2821 actgccataa ccttgagcaa tccatttatc ctgacgttct gccggcaatt ccaccaatgg
     2881 cgtatagcgg aacacaaaca caccacgcgc atcagaacgg cgatcttgca aaccgcccat
     2941 acggccaatg gcttcagaaa gcgataagcc tctggctgaa aaaccgattt cttgtgttct
     3001 ccccaccgca cccatagacg taaaggtata gggattggta atcatggtaa ccacatcacc
     3061 gcgacgcagc aaaatatttt gtcgcggatt tgcaactaaa tcttccaagg caacagttcg
     3121 tactacattg ccacgtgtca gctgcacatt cgtatcctgc acatttgccg ttgaaccacc
     3181 taccgcagcc accgcatcca acacacgctc accggctgcc gtcagcggca tacgcacact
     3241 attcccagca cgaatcaccg acacattcgc cgcattattc tgcaccaaac gcaccatcac
     3301 ttgtggctga ttggccattt ttttcaggcg gcctttaata atttcctgaa cctgaccagg
     3361 cgttttaccg accaccgaaa tatcgccaac aaacggcaca gaaaccgtac cacgtgccgt
     3421 gaccaactgc tctggcaact tagtttgatg cgcactaccc gagcccatcg aagaaaggcc
     3481 accaccaaac aatactgccg gcggcgcttc ccaaatcata atatccaata catcaccaat
     3541 atttagcgta ccagccgaag cataaccatc gccaaactga gtgaatgact gatttatctg
     3601 agccttatat aataactgag caaccgtatg attcacatca atcagctcca cttcaggaat
     3661 ttgaacttca gattgttgcc ctaaagagac aatttttttt gcgctggggc ctgatgaagg
     3721 aatcgcagag catcctacaa ttaaacttcc acacaataat aatactgcgt gacgaatata
     3781 aaatttcact ttaaacacaa gccaaatcct aatataatta taaatggcct aattatagca
     3841 cttaatcgaa ataaatttat gagtacgtag agtataatta gtattcttct ttccaacttc
     3901 cttatactta tatacttata gattctaaaa tcatgaaaag aattctttgc attacaggta
     3961 ccagagccga cttcggcaag ctaaaacctt tattagccta tattgaaaat cacccagacc
     4021 ttgaattgca tttgattgta actggtatgc atatgatgaa aacatatggc agaacctaca
     4081 aggaagtaac tcgagaaaac tatcaacata catatctgtt ttcaaatcaa atccaaggtg
     4141 aaccaatggg tgccgtttta ggcaatacca ttacgtttat ctctcgtcta tctgatgaaa
     4201 ttgaacctga tatggtcatg attcacggcg accgtttaga agcactagca ggcgcagctg
     4261 taggtgcatt aagcagccgt ttagtttgcc atatcgaagg tggtgaacta tctggtacag
     4321 tagatgactc cattcgtcat tctattagta aactttctca tatccacttg gtagcaaatg
     4381 aacaagctgt cactcgccta gtgcaaatgg gagaaaaaag aaagcatatt cacatcatcg
     4441 gctcccccga tttagatgtt atggcctctt ccaccctccc atccttagaa gaagtcaaag
     4501 aatattacgg tttaccatac gaaaattatg gtatttctat gtttcacccc gtgactacag
     4561 aagcacattt aatgccacaa tatgcggccc aatatttcaa agcattagaa ttaagtggcc
     4621 aaaatatcat tagcatctac cctaataatg acactggcac tgaaagtatt ctgcaagaat
     4681 tattaaaata tcaatctgat aaatttattg catttccttc cattcgattt gaatattttt
     4741 tagtcttatt gaaacatgct aaatttatgg tcggcaactc aagtgcaggt attagagaag
     4801 ctcctctcta cggtgtccct tcaattgatg ttggtacacg ccaaagtaac cgccatatgg
     4861 gaaaatctat tattcataca gattatgaaa ctaaaaatat ctttgatgcg attcaacaag
     4921 catgcagttt aggcaaattt gaagcagatg atacctttaa tggcggagat actcgcacca
     4981 gcacagaaag atttgctgaa gtaatcaaca atcctgaaac gtggaatgtt tctgctcaaa
     5041 aacgttttat cgatttgaat ctttaaatta tggaaaaaca aaatattgcg gttatacttg
     5101 cgcgccaaaa ctccaaagga ttgccattaa aaaatctccg gaaaatgaat ggcatatcat
     5161 tacttggtca tacaattaat gctgctatat catcaaagtg ttttgaccgc ataattgttt
     5221 cgactgatgg cgggttaatt gcagaagaag ctaaaaattt cggtgtcgaa gtcgtcctac
     5281 gccctgcaga gctggcctcc gatacagcca gctctatttc aggtgtaata catgctttag
     5341 aaacaattgg cagtaattcc ggcacagtaa ccctattaca accaaccagt ccattacgca
     5401 caggggctca tattcgtgaa gctttttctc tatttgatga gaaaataaaa ggatccgttg
     5461 tctctgcatg cccaatggag catcatccac taaaaaccct gcttcaaatc aataatggcg
     5521 aatatgcccc catgcgccat ctaagcgatt tggagcagcc tcgccaacaa ttacctcagg
     5581 catttaggcc taatggtgca atttacatta atgatactgc ttcactaatt gcaaataatt
     5641 gtttttttat cgccccaacc aaactttata ttatgtctca tcaagactct atcgatattg
     5701 atactgagct tgatttacaa caggcagaaa acattcttaa tcacaaggaa agctaaatgc
     5761 aaaacaacaa cgaatttaaa attggtaatc gttcagtagg ttacaaccac gaaccattga
     5821 ttatctgtga aatcggcatc aatcatgaag gctctttaaa aacagctttt gaaatggttg
     5881 atgctgccta taatgcaggc gctgaagttg ttaaacatca aacacacatc gttgaagacg
     5941 aaatgtctga tgaggccaaa caagtcattc caggcaatgc agatgtctct atttatgaaa
     6001 ttatggaacg ttgcgccctg aatgaagaag atgagattaa attaaaagaa tacgtagaga
     6061 gtaagggtat gatttttatc agtactcctt tctctcgtgc agctgcttta cgattacaac
     6121 gtatggatat tccagcatat aaaatcggct ctggcgaatg taataactac ccattaatta
     6181 aactggtggc ctcttttggt aagcctatta ttctctctac cggcatgaat tctattgaaa
     6241 gcatcaaaaa gtcggtagaa attattcgag aagcaggggt accttatgct ttgcttcact
     6301 gtaccaacat ctacccaacc ccttacgaag atgttcgatt gggtggtatg aacgatttat
     6361 ctgaagcctt tccagacgca atcattggcc tgtctgacca taccttagat aactatgctt
     6421 gcttaggagc agtagcttta ggcggttcga ttttagagcg tcactttact gaccgcatgg
     6481 atcgcccagg tccggatatt gtatgctcta tgaatccgga tacttttaaa gagctcaagc
     6541 aaggcgctca tgctttaaaa ttggcacgcg gcggcaaaaa agacacgatt atcgcgggag
     6601 aaaagccaac taaagatttc gcctttgcat ctgtcgtagc agataaagac attaaaaaag
     6661 gagaactgtt gtccggagat aacctatggg ttaaacgccc aggcaatgga gacttcagcg
     6721 tcaacgaata tgaaacatta tttggtaagg tcgctgcttg caatattcgc aaaggtgctc
     6781 aaatcaaaaa aactgatatt agttaataat aaaatagatt aagctattct taaattcaga
     6841 atattgctta tctatattaa aaatttctaa tttttaaggt tctgattgaa atcagaacct
     6901 tatttcaact attacttttt actcataatc gaattatata ctttaggact ttataatatg
     6961 gctgttatta tatttgttaa cggaattcgg gctgtaaatg gccttgttaa atcatctatc
     7021 aatactgcaa acgcttttgc tgaagaagga ctggatgttc atttaattaa ttttgttggc
     7081 aatattactg gagcagagca tttatccccc ccattccact tacatcccaa tgtcaaaacc
     7141 tccagcatca tagatttatt taatgacatt ccagaaaatg ttagctgccg aaatattcct
     7201 ttttattcta tccatcaaca attcttcaaa gccgaataca gtgcccacta taagcatgtt
     7261 ttgatgaaaa ttgaatcttt attatctgaa gaagatagca ttatcttcac tcatcctctt
     7321 caactggaaa tgtatcgttt agcgaataat aatattaagt caaaagccaa gctaattgta
     7381 caaattcatg gtaactatat ggaagaaatc cataactatg aaattttggc acgaaatatc
     7441 gattatgttg attatcttca aacggtatct gatgaaatgc tggaagaaat gcattcccat
     7501 ttcaaaatca aaaaagacaa attagttttt attccaaaca tcacttatcc catttcatta
     7561 gaaaaaaaag aagctgattt ctttattaag gataatgaag acattgataa tgctcagaaa
     7621 tttaaacgta tctctattgt tggcagtatt cagccaagaa aaaaccaatt ggatgccatt
     7681 aaaatcatca ataaaattaa aaatgaaaat tacattttac agatatatgg caaatctatt
     7741 aataaagatt actttgaatt aattaaaaaa tatattaaag acaataagtt acaaaaccgt
     7801 atcttattca aaggtgaatc ttccgagcag gaaatttatg agaatacaga tatcctaatc
     7861 atgacatctc aaagcgaagg ctttagttat atatttctag agggtatggt gtacgatatc
     7921 cctatccttg cctataattt taaatatgga gcgaatgatt ttagcaatta taatgaaaac
     7981 gcttcagttt ttaaaactgg tgatatttct ggaatggcaa aaaaaataat tgagctatta
     8041 aataacccag aaaaatataa agaattagtt caatataatc acaatcgctt cttaaaagaa
     8101 tatgcaaaag atgtggttat ggctaaatat ttcactattc ttccgcgcag ctttaataac
     8161 gtatcattat cgtctgcttt cagccgaaaa gaattggacg aattccaaaa tattactttt
     8221 tctattgaag attctaatga tttagctcat atttggaatt tcgagctaac caatcctgca
     8281 caaaatatga atttttttgc tttagttggc aagcgaaaat ttccaatgga tgctcatatc
     8341 caaggaacac agtgtacgat taagatagct cataaaaaga cagggaattt attgtcgctt
     8401 ttactaaaaa aacgaaatca gttgaattta tcaaggggat ataccttaat tgcagaagat
     8461 aatagctatg aaaaatatat tggagcaata tctaataaag gtaactttga aattattgca
     8521 aataaaaaga actcattagt tactataaac aaaagtacct tagagttgca tgagattccc
     8581 catgaactac atcagaataa attactgatt gctttaccca acatgcaaac gcctctaaaa
     8641 attactgatg ataatttaat acctatccaa gcctccataa aattagaaaa gattggaaat
     8701 acttattacc catgtttctt gccatctggc atatttaata atatctgctt agattacggt
     8761 gaagaatcca aaattattaa ttttagtaaa tattcttata aatatatcta tgactcaatt
     8821 cgtcatattg agcaacatac agatatatcg gatattatcg tttgcaatgt ttattcttgg
     8881 gaacttattc gtgcctcagt tattgagagc cttatggaat ttaccggaaa atgggaaaaa
     8941 cactttcaga cttctcctaa aattgattat cgatttgatc atgaaggtaa gcgttcgatg
     9001 gatgatgtct tttcagaaga aacatttatt atggaatttc cgcgtaaaaa tggtatagat
     9061 aagaaaacag cagccttcca aaatatacca aacagtattg taatggagta tccgcagacc
     9121 aatggttaca gtatgcgcag tcattcactg aaaagtaatg tagttgcggc aaaacatttt
     9181 cttgaaaaat taaataaaat taaggtagat attaaattta aaaagcatga ccttgcaaac
     9241 atcaaaaaaa tgaatcgaat tatttatgag catttaggca ttaacataaa tatcgaagca
     9301 tttctaaaac cacgattaga aaaatttaag cgtgaagaaa aatattttca tgatttcttc
     9361 aaaagaaata attttaaaga ggtaattttt ccaagcactt attggaatcc aggtattatt
     9421 tgtgctgcac ataaacaagg tattaaggta tctgatattc aatatgctgc cattactcct
     9481 tatcatcctg cgtattttaa atcaccaaaa tcacattacg ttgctgataa attgttctta
     9541 tggtctgaat attggaatca tgagctttta ccaaatccaa cacgagagat tggttctggt
     9601 gccgcatatt ggtatgcatt agatgatgtg agattttcag aaaaactgaa ttatgactat
     9661 atctttctat ctcaaagtag gatttcttcg cgcttgctta gttttgcaat tgagtttgca
     9721 ttaaaaaatc ctcaactaca gcttttattt tctaagcatc cagatgaaaa tatagattta
     9781 aagaacagaa ttattcctga taatcttata atctccacgg aatcttctat acaaggcatc
     9841 aatgaatctc gcgttgctgt aggtgtttat tcaactagct tatttgaggc attagcatgc
     9901 ggcaaacaaa cttttgttgt taaatatccg ggatatgaaa ttatgtcaaa tgaaatagat
     9961 tcagggttat tctttgcagt agaaacacct gaagaaatgc ttgagaaaac aagcccgaat
    10021 tgggtggctg tggcagatat tgaaaaccag ttttttggcc aagaaaaata atttttaagt
    10081 taatctttaa aagtgcaata tttttcttat tttaaatatt acactttatt cttttaatca
    10141 taggaactca catgtattct gaacagggaa ttaataatac tattaacata tctactacat
    10201 ctttaaccaa tgccacgcaa ctaactgtga tcgggaataa taactctgta tatataggta
    10261 ataattgtaa aatcgtcagc tccaatatta gattaaaagg aaataatata accttattta
    10321 tagctgatga tgtagaaatc atgggactag tatgttccct tcattcggac tgctctttac
    10381 aaattcaagc caagaccact atgggcaatg gagaaattac cattgctgaa aaaggtaaga
    10441 ttagtattgg caaagattgt atgctggcac atggatatga aattagaaat actgatatgc
    10501 atccaattta ttctttagaa aatggcgaac gaataaacca tggtaaagac gttattatcg
    10561 gtaatcacgt gtggcttggc cgcaatgtta ctatattaaa aggtgtatgt attccaaata
    10621 atgtagttgt aggttctcat actgtgctat ataaaagttt taaagaacct aattgtgtaa
    10681 tagcaggttc acctgcaaaa atagtaaaag aaaatattgt atggggaaga aaaatgtatc
    10741 attcaactat gtatgatgac cctactttaa atgaatttta taaataactt aggggcttag
    10801 gaagcaaaat catcaaaaaa cctgataagc tcctaat
//

