LOCUS       MN115826               27237 bp    DNA     linear   BCT 28-JUL-2020
DEFINITION  Plesiomonas shigelloides strain O39H11 putative O antigen gene
            cluster, partial sequence.
ACCESSION   MN115826
VERSION     MN115826.1
KEYWORDS    .
SOURCE      Plesiomonas shigelloides
  ORGANISM  Plesiomonas shigelloides
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacterales incertae sedis; Plesiomonas.
REFERENCE   1  (bases 1 to 27237)
  AUTHORS   Wang,X. and Xi,D.
  TITLE     Novel O-antigen gene clusters of Plesiomonas shigelloides and their
            molecular serotyping by TaqMan MGB probes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27237)
  AUTHORS   Wang,X. and Xi,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-JUN-2019) Tianjin Key Laboratory of Microbial
            Functional Genomics, TEDA College, Nankai University, 23 Hongda
            street, Tianjin 300457, China
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: de novo v. VelvetOptimiser v2.2
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..27237
                     /organism="Plesiomonas shigelloides"
                     /mol_type="genomic DNA"
                     /strain="O39H11"
                     /db_xref="taxon:703"
                     /note="G6004"
     gene            1..2031
                     /gene="rep"
     CDS             1..2031
                     /gene="rep"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase Rep"
                     /protein_id="QLL91121.1"
                     /translation="MRLNPRQQEAVEFVSGPCLVLAGAGSGKTRVITNKIAHLIRGCG
                     YQARHIVAVTFTNKAAREMKERVAQTLGRGETKGLLVSTFHSLGLEILKREYKALGLK
                     AGFSLFDDQDQMALLKELTEDCLKGDKDLLSQLVQKISGWKNDMILPEQAKVRAKGER
                     DILFALCYEQYARQLRACNVLDFDDLILLPTLLLRTQEEVRERWQNRIRYLLVDEYQD
                     TNTSQYELVKLLVGARARFTVVGDDDQSIYSWRGARPQNLTLLRQDFPALKVIKLEQN
                     YRSSQRILKSANILIANNPHEFEKQLFSELGPGEMLRVLQANNEEHEAERVVGEIIAH
                     RFLNKTQYKDYAILYRGNHQSRTLEKMLMQNRIPYKISGGTSFFARAEIKDIMAYLRL
                     LINPDDDTAFLRVVNTPRREIGPVTLEKLGTWAHSRGNSLFAASFDLGLEQHLQGRGL
                     EALRQFTRWITEIADRAQRGDPVAALRDLVHGIHYESWLYETSASPKVAEMRMRNVST
                     LFGWVTEMLEGKDGEEPMTINQVVQRLTLRDMLERGEDDAEADQVQLMTLHASKGLEF
                     PHVFLIGMEEGILPHQTSLDEDNVEEERRLAYVGITRAQKTLTFTLCKERRQYGELLR
                     PEPSRFLHELPQDDVEWEVRKAPVSAEQRQQRGRQGVAGLREMLAQAKKRPE"
     misc_feature    <1..>27237
                     /note="putative O antigen gene cluster"
     gene            complement(2186..2596)
                     /gene="rfaH"
     CDS             complement(2186..2596)
                     /gene="rfaH"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription/translation regulatory transformer
                     protein RfaH"
                     /protein_id="QLL91122.1"
                     /translation="MQNIRYFCPMLTVKKQRRGQWQEEAEALFANYLFVHFNPDQLSV
                     TRVQATRGVARLVRFGETLARVPDEVLIDLARRYNPLVALPEEGKVCSQPMCTALQQV
                     LVDIERESNGEVRALRFLQLLQDHRLLASRHREE"
     gene            complement(2937..3263)
                     /gene="c5"
     CDS             complement(2937..3263)
                     /gene="c5"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c5 family protein"
                     /protein_id="QLL91123.1"
                     /translation="MSDDAISERIKPVGGVYLADAAATAKPSGPRTGEQVYNGACIAC
                     HGSGALGAPKFRDAALWGPRLKQGIDTLQKHAIAGLNQMPARGTCTDCSDDEIKAAIE
                     YMTSGL"
     gene            3904..5010
                     /gene="wzz"
     CDS             3904..5010
                     /gene="wzz"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz"
                     /protein_id="QLL91124.1"
                     /translation="MSKASEPQQTPYLIPQGVYPTYMPKAEDEIDLFELLGTLWKKKW
                     VILCVTLLTTGLAAVYAFTAKEQWTAKTYIQAPRIAELGSYLKFRQAYARILNQSLDT
                     GALARGLFSDLILLAESPDTKASFLSHTEYYKKETADLSSETDKKIWLDNQINKSIVI
                     TPPDEKKGSNYYTVEFSADSAKNAYQLLQAYLKDVNGQAVTLNLSEFDQNINALLVNL
                     KKEVQDIDFKKKAEKLDQIAFIQRDLTTAEQAGITDYRSSKNSFDNAQSSYKFLLGEK
                     LLSAELKATKDAPIIYPFRYYEVKRQIDELEGMLRDNIQAQAYRYQMMPSEPLQKDKP
                     KKALILVLGALLGSMLGIISAFLINAIEQRKLRG"
     gene            5033..6073
                     /gene="wblB"
     CDS             5033..6073
                     /gene="wblB"
                     /codon_start=1
                     /transl_table=11
                     /product="WblB protein"
                     /protein_id="QLL91125.1"
                     /translation="MIKGRKIKIAIIGCGRISKNHFGSIEQLDNEFDLVAVCDNNPSV
                     LHAHKEQYKVPGYLSLDELLEKESVDVISLCTPSGLHSIQAIRAAKSGVHVISEKPMA
                     TKWADGLAMLKACDDAGVRLFVVKQNRRNSTLQLLKRAVTEKRFGKIHMVHVNVFWTR
                     PQEYYDRAAWSGTWDMDGGAFMNQATHYVDLLHWLIGPVEKVHAITSTHRDIDVEDTG
                     VVNIKWRNGAVGSMAVTMCTYPKNYEGSITILGEKGTVRVGGVAVNEIQDWIFDEEKD
                     YDSQITDANYQTTSVYGFGHPPYFKNVADVLRGKAEPETDGREGLKSLELLIATYRSA
                     RDGKEIGLPLNL"
     gene            6095..7369
                     /gene="vipA"
     CDS             6095..7369
                     /gene="vipA"
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide biosynthesis
                     UDP-N-acetylglucosamine C-6 dehydrogenase TviB"
                     /protein_id="QLL91126.1"
                     /translation="MNISDLKIGIIGLGYVGLPLAVEFGKHFPTVGFDIKTERVAELR
                     DGKDSTLECSSEELVSAHFLEYTCNLDDIKQCNFYIVTVPTPITDEKTPDLMPLRKAS
                     EALAKVIKSGDIVVFESTVYPGATEEVCLPIIEKLSGLVYNKDFFAGYSPERINPGDK
                     VNRLTTIMKITSGSTPEVAELVDNVYKKIITAGTHKASSIRVAEAAKVIENTQRDLNI
                     AIINEFAKIFNKLGIDTEEVLKAAGTKWNFLHFKPGLVGGHCISVDPYYLTHKAQEVG
                     YRPEVILAGRRINDGMGEYVATQLVKKLSSKKIHIDEARVLVMGFTFKGDCPDVRNTK
                     IIDIIHELKEFNMHVDVFDEWACKNEVKHEYGIELIDSLEENTYDAIILAVDHSSTKN
                     MGASAIRKLGKAQHVIYDVKYVLPLGEADIRL"
     gene            8049..9128
                     /gene="wecE"
     CDS             8049..9128
                     /gene="wecE"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="QLL91127.1"
                     /translation="MQFIDLAAQQARIKNEIDAAIQNVLQHGAYILGPEIAELEQKLA
                     DFTGAKYCISVANGTDALQIAQMALGIGPGDEVITPGFTYIATAETVALLGAKPVYVD
                     VCPKTYNLDPIKLESAITPNTKAIIPVSLYGQCADFDTINSIAAKHDIPVIEDAAQSF
                     GASYKGKKSCNLSTIACTSFFPTKPLGCYGDGGAIFTNDDELALIMRQISRHGQDRRY
                     HHIRVGVNSRLDTLQAAILLPKLKILHEEIELRNRVANTYTHLLNEAGILSTPCVEEH
                     NISAWAQYTIRVKNRSEVQQKLQEAGIPTAVHYPIPLNKQPAVADNCIQLPIGDEIAQ
                     EVMSLPMHPYLTEEEIKRVVDSLAQ"
     gene            10323..11570
                     /gene="wzx"
     CDS             10323..11570
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="QLL91128.1"
                     /translation="MIMFITKNTFFRQIILLAGGTAAAQLINLAILPILTRIYTPSDF
                     GIFAVMSASVAIVNVFLSMRYENAIIAVKTDADALVGTFSVMVLACVVSLALVFFWSV
                     IGFGVELNTKYLLIGYIVIVFSLVTCFTQALYFLCNRLSNYHVMTNGRIYGALSLAVL
                     SISWGYFLHNFWGLLLGSLLGVSINFLYLWCSLGETKNKLFTPNKKVVKYLKDNIRFP
                     KYLVVSSLIDRSGSQGYLILLTKLYGEGVAGSLSLYNRVAGFPSVLVGTAIGDVFKRN
                     ASEQLRKYGECKRLVLLTAAGLLVIAIIPFFLLLFFGPHIFEVVFGSEWRQAGEFARF
                     LAPVFLLGFIVSPISSLIYLEENQKYDLYVQSILLIFLILGLGFSLFFSKVYFAIIAY
                     AISYFFKYCFELKVCWRIASGER"
     gene            11572..12696
                     /gene="wbpG"
     CDS             11572..12696
                     /gene="wbpG"
                     /codon_start=1
                     /transl_table=11
                     /product="putative LPS biosynthesis protein WbpG"
                     /protein_id="QLL91129.1"
                     /translation="MTGLDSYQVCSFCVMDTTDPEITFDENGRCNHCVAAEKKLAENW
                     FPNENGEKKLKAIAEEIKRNKGSKEYDSIIGISGGIDSSYLLHLAKVEMNLNPLVVHV
                     DAGWNSEIAVNNIEKMVKKLDLDLFTYVVDWHEMRDLQVAYLKSSLANQDVPQDHAFF
                     AKLYQIADENNISYTITGSNLTSESILPASWGYDASDSIQIKAVFDKFGQGTLKNYPI
                     MSWWKNKIYWPYLRRMKIIRPLNFIDYNKNEAIRFLQINYDWQYYGGKHHESKWTKFF
                     QAHYLPKKFGFDKRKAHLSSMIVAGQITRDEALKELSKPLYNERDLKEDMFFIEKKLN
                     LEEGMLVKLMQLPNKSYMDYPNDRKIIGLFRSMKRIFLRK"
     gene            14023..15354
                     /gene="wzy"
     CDS             14023..15354
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="QLL91130.1"
                     /translation="MGLFKLGKSRLFFLVLALQLALLLIYLNDNIVNVGEMMGTGLSF
                     LAFYIFFFVIVVFSLLLNRRIYLRFHFFIFMLLIFWISYRTINDLGDMEYLKQITIAT
                     TGGMLFFYILGASIRVCYCDSYTNKGDVFLSKVALIVFFMLQLWMLYKFSFRLRSDIF
                     YLVGVNGLYQRAGNFLSISFIIVSFYYLQLMLNRVNKYISISLFFWLVIYTVSTLIAL
                     VGSQMFGSNSATGVILGIYVVTLMMTLIISQKSLWINYINGRLALPFSKEIIIKMCFM
                     ALIAFVFLMIILVLVIVISGFNVNSLRLVGFGLDTNTSLLSRIKILLDLGETQLSYAP
                     FFGNMNVAYLTVGDAGLFLHSFFPYVMANLGIVGLWCTLVLFISLLLQLYREGKSGET
                     IGLYDFQISIVAIYSFLIFFYILFFANMTTSISWPVLWFTFGFISKPLGFK"
     gene            15354..16493
                     /gene="gt"
     CDS             15354..16493
                     /gene="gt1"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="QLL91131.1"
                     /translation="MKNIHITLTEFRNESRVLKEISSLETSRVFDSFTVISLGADDLS
                     KEEVINSKAKIQRVNLISRKLPKSSFFQMIKFIEFIFKSFLIIKNENPDVVNVHTLSL
                     LPFGWLLKKTLNVKLVYDAHELETEKNGLHGVRQRISKWIEVNFIYFCDLIIVVGDNI
                     ADWYANTYNIQRPLVVKNSPRAILKSKENLFRENFGILQEQKIILYQGGLIKGRGIEL
                     IIEAFEARIDTSAVVVFMGYGELEHLVKQAAEKNENIFYFPAVHPSIVLEYTASADIG
                     ISLIEPTCLSYYFCMPNKLFEYAMVGLPVIVSNMKEMADSVLGANFGTVLSNYSIEDI
                     NAAIDNLIKHDFSELSENARAFAKAHSWEQQEAVMIEGYLRILGQ"
     gene            17113..17877
                     /gene="hisF"
     CDS             17113..17877
                     /gene="hisF"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="QLL91132.1"
                     /translation="MLRKRVIPVLLLRDGGLVKGEKFKKHKYVGDPINAVRIFNEKEV
                     DELVFVDISVGFSGNEPDYELIGNMASEAFMPIAYGGGIRSVDQVEKLFRLGIEKVII
                     NSEFHNNPELVKECSQIAGAQSIVVAIDVKKSLFGRYEVYTHNGTYKTGVCPVEYAKK
                     AQVYGAGEIVLTSIDREGSAQGLDLDLIKKVTAAVEIPVIVQGGVGHLEHIKQAVKNS
                     GASAVAAGSFFTFHGKHKAVLLTYPAYEELEDLFLY"
     gene            17890..19035
                     /gene="wbpG"
     CDS             17890..19035
                     /gene="wbpG"
                     /codon_start=1
                     /transl_table=11
                     /product="putative LPS biosynthesis protein WbpG"
                     /protein_id="QLL91133.1"
                     /translation="MVDCNYQMCTRCVMDTTDPEIIFDALGICNHCHEFDNVTSKRWF
                     PNDDGKAKLKQIFNKIKAERKDYEYDCILGLSGGLDSAYLALVMKEYGMRPLVVHIDA
                     GWNSELAVYNIEKVVKYCGYDLHTHVMNWPEIRDLQLAYLKAGVANQDVVQDHAFFAS
                     LYHFAVEKKIDYVISGGNIATEAVFPQSWHHAAMDAVNLKAIHKRFGKLQLKDYKVIS
                     FLQYYFYYPFIKKMKTVRPLNYIPYSKEVALAELQEKVGYKPYGRKHGESRFTKFFQN
                     HYLPTKFNMDKRKPHLSSMVLSGLMSREQALEELSKPLYDKNELREDKHYIAKKLGIT
                     VEQLNEYVTSPGHDYSEYPNWDSRYAFMKKAQSFVSKVLGRNVKNYS"
     gene            19172..20131
                     /gene="gt"
     CDS             19172..20131
                     /gene="gt2"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="QLL91134.1"
                     /translation="MSIYDVGASKGRLDRIHNAPGRVLAKALELDADIYQLHDPELIP
                     IGVKLKKHGKVVIFDAHEDVPKQLLGKPYLNKPAKWLLSKIFSVYERWACRKLDAVIT
                     ATPYIRDKFIAMGVRSVDINNYPLLDELSTDKVDWSQKKAQVGYVGGLGRIRGIHEMV
                     QAMALVESDVRFAVGGSFSEASFEQAVKAEAGWVKTDHLGWLDRTGVKQVLNDSVAGL
                     VTLHPVINYLDSLPVKMFEYMAAGLPVIASNFSLWKEIIEGNQCGLCVDPLAPQAIAE
                     AIDYLVTHPVEAEQMGRHGQKAVHEKYNWCIEEQKLLQFYKTL"
     gene            20141..20299
                     /gene="qnlB"
     CDS             20141..20299
                     /gene="qnlB"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="QLL91135.1"
                     /translation="MQRILTIIGARPQFIKASVVSRAIQQTDGIEEIILHTGQHFDAN
                     MSDIFSTN"
     gene            20365..20535
                     /gene="wecB"
     CDS             20365..20535
                     /gene="wecB"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="QLL91136.1"
                     /translation="MLTEIEQALLTHKPDRVLVYGDTNSTLAGALAAAKLHIPVAHVE
                     AGFRSFNMQIPE"
     gene            20596..21057
                     /gene="wbpI"
     CDS             20596..21057
                     /gene="wbpI"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="QLL91137.1"
                     /translation="MQNLNNEGFANKQVQGLQVGDVMQDAVLLFAKKAVAPAGELSDE
                     FILATLHRAENTDSPERLANIVNALNQLHQTLVPVVLPLHPRTRKLIAEQGLELNVQL
                     TDPVGYFEMVWLLDHCQLVLTDSGGVQKEAFSLVRLVSRCVTKPRADKSGS"
     gene            21199..22422
                     /gene="wbuB"
     CDS             21199..22422
                     /gene="wbuB"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="QLL91138.1"
                     /translation="MSKTVWIVQQYASTPATGIGGRHYYLGRELVKQGYKVYLIASAS
                     HHLLREKPVLNQQFKIETLEKGFYFVWVNMPAYAEAHSKQRALNWFLFPWQIQKLARK
                     IADKPDTVLSSSPSLIAFLGAQRLAKKFKARLVFEVRDIWPLTLTEIGGYSPKHPFIR
                     VMQWVEDKAYRDSDAIVSNLKNSVEHMASRGMARDKFSWVPNGFSLDEVNKKIPLNNT
                     AATQLPKNKFIIGYTGTLGVANALHTLIEAAERLQEYTEIAFVLVGAGKEKSALQSLV
                     VEKQLRNIFFIDPIPKVEIQSMLAEFDACYIGWLNDGLYRFGIGANKIPEYLYSGKPV
                     LHAYSGACDPIKEAKAGLQVRAQDSEQLADAVLSLYQMPEEERLAMGESGRKAALKQY
                     EYGQLANQLIKVLFN"
     gene            23035..23988
                     /gene="qnlA"
     CDS             23035..23988
                     /gene="qnlA"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="QLL91139.1"
                     /translation="MSIAVTGGTGFVGTVLVNKLKQRNVRLIQRRKVELISSIHSCHL
                     HEISSSTQFGDCLKSCDVVIHSAALVHVMTDSVSKPLEAYREVNTLGTANLARQAALS
                     GVKRFIFISSIKVNGEKTCTNNQFTSADEHAPEDDYGLSKSKAEQHLFDIGKKTGMEI
                     VVIRPTLVYGPGVKANFSSLMNLVSKGIPLPFGCITKNKRSLVSVDNLVDLIVTCIDH
                     PKAANQVFLVSDDRDVSTSEMVREMAIALGKTTWQLPVPIWCYKLIGKLFNKSDIVDR
                     LIGSLQVDISHTKNTLGWKPPQTLQDGFKQTAQAFLQANRK"
     gene            25291..26553
                     /gene="wbgZ"
     CDS             25291..26553
                     /gene="wbgZ"
                     /codon_start=1
                     /transl_table=11
                     /product="WbgZ"
                     /protein_id="QLL91140.1"
                     /translation="MIARLEHLPCEVLSIPGMVDLVEGRAQISNLKKVSIDDLLGRDP
                     VAPDAKLMAENITGKAVMVTGAGGSIGSELCRQIVRYKPAKLVLFELSEYALYAIEKE
                     LSTLCDKEGLDVAVVPLLGSVQRQNRLQMVMKSFGIQTVYHAAAYKHVPLVEHNVVEG
                     VRNNVFGTLYCAESAIESGVETFVLISTDKAVRPTNTMGTTKRLAELVLQALSVRQSQ
                     TRFCMVRFGNVLGSSGSVVPLFEKQIAQGGPVTLTHRDIIRYFMTIPEASQLVIQAGA
                     MGHGGDVFVLDMGDPVKIYDLAKRMIRLSGLSVRDDKNPDGDIAIEVTGLRPGEKLYE
                     ELLIGDSVQGTSHPRIMTANEVMLPWQDLSLLLKELDQACHDFDHERIRSLLLQAPAA
                     FNPTDDICDLVWQQKKSLLSQASNVIRL"
     gene            26740..27237
                     /gene="aqpZ"
     CDS             26740..27237
                     /gene="aqpZ"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin Z"
                     /protein_id="QLL91141.1"
                     /translation="MISAAFPQLGIGFLGVALAFGLTVVTMAYAVGHISGAHFNPAVT
                     LGLWAGGRFPAARVLPYIIAQVIGGIAAAAVLYGIASGKAGFDATTSGFAPLAIGLTL
                     TIIHLVSIPVTNTSVNPARSIAAAVFQGTWALDQLWMFCLIPSLGGIAGGLIYRALLA
                     RPAEA"
BASE COUNT     7607 a   4955 c   6295 g   8380 t
ORIGIN
        1 atgcgtttaa atccccgtca gcaggaagca gttgaatttg tcagcggacc ctgtctggtg
       61 ctggctggcg ccggctcggg aaaaacccgc gtaattacca acaaaattgc ccacctgatc
      121 cgcggctgcg gttatcaggc gcgccatatt gtggcggtga cctttaccaa caaggccgcg
      181 cgtgagatga aagagcgggt agcgcagacg ctcggtcgcg gtgaaaccaa aggcttgttg
      241 gtgtccacct tccactctct gggcttggaa atcttaaagc gcgaatacaa agcgctgggg
      301 ctgaaagccg gtttttcgct gtttgacgat caagaccaaa tggcgctgct caaagagctg
      361 accgaagact gtctcaaagg cgataaagac ctcctcagcc agctggtgca aaaaatctcc
      421 ggctggaaaa atgacatgat cttgcccgag caggcaaaag tgcgcgccaa aggtgagcgc
      481 gatatcttgt ttgccctgtg ttatgagcag tatgcacgcc agctacgcgc ctgcaatgtg
      541 ctggattttg atgatctgat tttgctgcca accttattat tgcgcaccca agaagaggtg
      601 cgagagcgtt ggcaaaatcg cattcgctat ttattggtgg atgagtatca agataccaac
      661 accagccagt acgagctggt gaaattgctg gtcggcgcgc gcgcccgttt caccgtggta
      721 ggggatgatg atcagtcgat ttactcatgg cgtggtgcgc gtccgcagaa tttgaccttg
      781 ttgcgccaag attttccggc gttgaaagtg atcaagctgg agcagaacta ccgctcctcg
      841 cagcgcatat taaaatcggc caacatcttg attgccaaca acccgcatga gtttgaaaag
      901 caactgttct cggagctcgg ccccggtgag atgctgcgtg tgctgcaggc taacaatgaa
      961 gagcatgagg cagagcgggt ggtcggcgag atcatcgcgc accgtttctt gaacaagacc
     1021 caatataaag attacgccat tttgtaccgc ggtaatcacc agtcgcgcac gctggaaaag
     1081 atgctgatgc aaaaccgcat tccgtacaag atctcgggtg gcacctcttt ctttgcccgc
     1141 gccgaaatca aagacatcat ggcctacttg cgcctgctga ttaatcccga tgatgacacc
     1201 gcgttcctgc gcgtagtgaa taccccgcgg cgtgaaatcg gtccagtgac cttggaaaag
     1261 ctcggtacat gggcgcacag tcgtggcaat agcctgtttg ccgctagctt tgatttggga
     1321 ttggagcagc atttgcaggg gcgtgggctg gaggctctgc ggcagtttac gcgttggatc
     1381 accgagattg ccgatcgcgc ccagcgtggc gatccagttg ccgcgctgcg tgatttagtg
     1441 catggcatcc attatgaaag ctggctctac gagacctccg ctagcccaaa agttgccgag
     1501 atgcgcatgc gcaacgtctc gaccctgttt ggctgggtga ccgagatgct ggaaggcaaa
     1561 gacggcgagg agccgatgac catcaatcag gtggtgcagc gcctcacctt gcgcgacatg
     1621 ttggagcgcg gcgaagatga cgccgaagcc gatcaagtgc agttaatgac gctacacgcc
     1681 tcgaaaggac tggagtttcc gcatgtcttc ttaattggga tggaagaggg gatcttgcca
     1741 caccagacca gtttggatga agacaatgtg gaagaagagc gccgcttggc gtatgtcggg
     1801 atcactcgcg cccagaagac cttgaccttt acgttatgta aagaacgccg ccagtacggt
     1861 gagttgctgc gcccagagcc gagccgcttc ttgcacgaac tgccgcaaga tgacgtagag
     1921 tgggaagtac gtaaagcacc agtcagcgcc gaacagcgtc agcagcgtgg ccgccaaggg
     1981 gtagccggat tacgcgagat gttggcgcag gcgaaaaaac ggcccgagtg atcttactgg
     2041 ccatgggctt agtgtctacg catataagtg tctactcata taagcgacta cagagataag
     2101 agcctaatta tttaggcgct tatatatgcg gaagacgccc gcaacgggcg tgcgcactat
     2161 gacattggaa tgccggaacg caggattatt cctctcggtg acgggaagcc aacagacgat
     2221 gatcttgcag taattgtaaa aagcgtagcg cacgaacttc cccattgctt tcacgctcga
     2281 tatccaccaa gacctgttgt aaggcggtac acatcggctg actacagact ttaccctctt
     2341 ccggtagtgc aaccagcggg ttgtaacgtc gcgctaaatc gatcagcacc tcatccggca
     2401 ctctcgccaa cgtttcgcca aaacgcacca accgcgccac gccgcgcgta gcttgcactc
     2461 gcgtgacact cagctgatcg ggattaaagt gcacaaacag gtaattggca aacagcgctt
     2521 cggcctcttc ctgccattga cctcgacgct gtttttttac cgtcagcatc ggacaaaaat
     2581 agcggatatt ttgcaactcc agatgttgcg ccgcccgact ttgctgtccg cgtttacaat
     2641 aaagaagata ccaggcgtcc atagatagtt ttgtgatgaa aataatgatt gcagtatgcc
     2701 acagagtgga tagccggtca gtctttgggt gtgatgtaac agtcagttta attatagggt
     2761 aggcagcaca aagcaccgtt cgcgcaaaat atcgccggtg aatcgtcagt gagagccagt
     2821 taagtcagag taatttagcg ctaacaacca tgccgcaaca tataaaggag gcatcaaggc
     2881 ctccttctat ctgcacgata ttcgtctcta tatgctgagt agctgcatcg cgtagcttat
     2941 aacccgctgg tcatgtattc gatcgcagcc ttgatttcat catcactaca atcggtacag
     3001 gttccgcgtg ccggcatctg gtttaaaccg gcaatggcgt gtttttgcag ggtgtcgata
     3061 ccttgcttca gacgcgggcc ccacagagcc gcatcccgaa acttaggtgc gcctaaggca
     3121 ccgctgccat gacaggcgat acaggcaccg ttatacacct gttcaccggt acgtggccca
     3181 ctaggtttgg cggtggccgc agcatcagcc agatacaccc cgccgactgg cttgatgcgt
     3241 tcgctgatgg catcatccga catatcagcc gcggcaaccc aacaggatat gccgagcagc
     3301 agggaggtca gaagagttaa cgccgcctgg cgaggcttag cgcagataga cttggcacgc
     3361 acaaagacag tgttcacaga ttttctccct aaataaccag cggcatcctt ttatcctgct
     3421 ttccttcata atcggtctga gcagggctgt gaaccgcagc ggttgaatat tgaccacccg
     3481 gttgtgttgc cagattataa gctaatagta aataaattga agcaattgcg cggggttctt
     3541 ttttgcaagg cagtcagcgt gcgacagctt gtacagctcc gcctcacaga atttacaaac
     3601 atactgttat ctttttgacg gtagatttgg ccttccatgg gcattgcttt ataatctgca
     3661 ctccaaattc tgcgggctat ccgccggttt gcaacaggga agtgggaggc gaaagatgcc
     3721 tcttcacatg gagcgttctc gatcatgccc tctatcccag atatcacttg tatcgcggtt
     3781 gtcgatatcc tgttttttgc gcagcgcttt gggagctgaa actcaagggc ggtagcgtgc
     3841 ttttttgtca ggtttattct ttacctttat ttttaaccca ttgataaata atggattgat
     3901 ttcatgtcaa aagcatctga accacagcag actccttatc tgatcccgca aggggtctat
     3961 ccaacctata tgccaaaagc agaggatgaa atcgatcttt tcgagctttt aggcaccttg
     4021 tggaaaaaaa agtgggtgat tttatgtgtc acattgctga ctacaggatt agcggcagtg
     4081 tatgccttta cagcaaaaga gcagtggaca gcaaaaactt atattcaggc accacgtatt
     4141 gctgaactag ggagttatct taaatttcgt caagcgtatg cacgtattct taatcaatca
     4201 ttagatacag gtgcattagc gagaggttta ttttcagatt taatcttatt agcagaatct
     4261 ccagatacga aagcctcttt tttatcgcat actgaatatt ataagaaaga gaccgcagat
     4321 ctctcatcag agacagataa gaaaatatgg ttagataacc aaattaacaa atctatagtc
     4381 ataacgcctc ctgatgagaa aaaaggtagt aactactaca cagtggaatt ttctgcagat
     4441 tctgctaaga acgcatatca attattacaa gcatacctta aagacgttaa tggtcaggcg
     4501 gtgacgttaa atctttcaga gttcgaccaa aatatcaatg cactattggt caacttaaaa
     4561 aaagaagtac aggatattga tttcaagaag aaagcagaga agttagatca aatagcattt
     4621 attcaacgag atttaactac agcagagcaa gctgggatta cagattatcg ctcaagtaag
     4681 aatagttttg ataatgcgca aagtagttat aaattcttgc ttggagaaaa actgttatca
     4741 gctgagctga aagcaactaa agatgcgcca attatttatc catttagata ttatgaagtg
     4801 aagcgtcaaa ttgatgagtt agaaggaatg ttacgcgata acattcaggc tcaagcatat
     4861 cgttatcaaa tgatgccatc tgagccatta cagaaagata aacctaaaaa agcactgatt
     4921 ttggtgctgg gtgcgttatt gggcagcatg ttgggtatta taagtgcatt tcttatcaat
     4981 gctatcgaac aaagaaaatt acgtggttaa tcgataattt agtgagtgta ttatgattaa
     5041 gggtagaaag ataaaaattg ccatcatcgg ttgtggcaga atatcaaaaa accattttgg
     5101 ttctattgag caattagata atgagtttga tctggttgca gtttgcgata ataacccatc
     5161 agttcttcac gctcataaag agcagtacaa ggttcccggt tatttatcat tagacgaatt
     5221 attagaaaaa gaaagcgttg atgtaattag cttatgtacg ccaagtggat tgcattcaat
     5281 acaagcaatt cgcgctgcta aatcaggtgt gcatgtcatc tcagaaaaac caatggcaac
     5341 caaatgggct gatgggttgg cgatgctaaa agcctgcgat gatgcgggtg ttcgattgtt
     5401 cgtggtaaaa cagaaccgca gaaattctac tttgcaatta ttaaagcgag ccgtgacaga
     5461 aaagcgcttt ggtaagatcc atatggttca tgtcaatgtt ttttggacta ggccgcaaga
     5521 gtattatgac cgtgccgcat ggtctggtac ttgggatatg gatggtggtg cgttcatgaa
     5581 tcaggctacc cattatgttg acttactgca ttggttgatt gggccagtag aaaaagtgca
     5641 tgcgataaca tcaacccatc gtgatattga tgttgaagat actggtgtag tgaatatcaa
     5701 gtggcgtaat ggcgccgtag gttctatggc cgttactatg tgtacttatc ctaaaaatta
     5761 tgaaggctcc atcactattt taggtgagaa aggcactgta agagtgggtg gcgttgctgt
     5821 caatgagatt caagattgga tctttgacga agaaaaagac tatgacagtc agataactga
     5881 tgccaattat caaaccacat ctgtatatgg ttttggtcat ccgccatact ttaaaaatgt
     5941 ggctgacgta ttaagaggaa aagctgagcc tgaaaccgat ggccgtgaag gtttaaaatc
     6001 tcttgaatta ctcattgcga catatcgttc tgcacgcgat ggtaaagaaa taggcctacc
     6061 tcttaatctg taattaaaac acttggattt taaaatgaat atctccgatt taaaaattgg
     6121 tatcattgga cttggttatg tgggtttacc gttagcggta gaatttggaa aacactttcc
     6181 tacagtgggt tttgatatca agacagaacg agttgctgaa ctgcgggatg gtaaagattc
     6241 gactttagaa tgttcaagtg aagagttggt tagcgcacat tttcttgaat atacctgcaa
     6301 tcttgatgac attaaacaat gtaactttta catcgtcaca gtaccaacgc cgattacgga
     6361 tgaaaaaaca ccggatttaa tgcctctacg caaagcttct gaggctttgg ctaaagttat
     6421 caagagcggc gacattgttg tgtttgaatc aaccgtctat ccaggggcta cagaagaggt
     6481 ttgcttacct atcattgaaa agttatcagg gcttgtttat aacaaagact tttttgctgg
     6541 ttacagtcct gagcgcatta accctggtga taaggtaaat agactaacaa cgataatgaa
     6601 gattacttca ggctctactc ctgaggttgc ggagttagtt gataatgtgt acaaaaaaat
     6661 tattaccgcg ggtacgcaca aggcttcatc tatacgcgta gctgaagccg caaaagtaat
     6721 cgagaacact cagcgtgatt taaatattgc gataattaat gagtttgcaa aaatatttaa
     6781 taaattaggc attgatacgg aagaagtgct taaggctgcg ggcactaagt ggaattttct
     6841 ccattttaaa cctggtttag tgggcgggca ttgtatcagt gttgatccat actatttgac
     6901 tcataaagca caagaagtag gctatcgacc agaagtaatt ttagctggcc gcagaattaa
     6961 tgatggaatg ggtgagtatg ttgccaccca attggtgaag aagttatcta gcaagaagat
     7021 ccatattgat gaggccagag tgctagtcat ggggttcact tttaaaggtg actgcccaga
     7081 cgtaagaaat actaaaatta ttgatattat acatgaatta aaagagttca acatgcatgt
     7141 tgatgtgttt gatgagtggg catgcaagaa tgaagtaaaa catgaatatg ggattgagtt
     7201 gattgattcg ctagaagaga atacttacga tgcaattatt ctcgctgttg accatagttc
     7261 aaccaagaat atgggcgcat cagctattcg caaattaggt aaagcacagc atgttattta
     7321 tgacgtgaag tatgtgcttc ctctcggcga ggcagatatt cgtctgtaat tttaagctaa
     7381 atttaacctt tctgactaag ctatcattgg cagaaaggtt aatgtattta gagtggtcag
     7441 ggttatataa tgagttatta caagcacgag tcagctatta ttgatgatgg agcgcgtata
     7501 ggagatggat gtcgagtctg gcattttgca catatttgta gtggagcact cattggccaa
     7561 ggcgtatcgt taggccaaaa tgtatttgta ggaaataaag ttaccattgg tgataaatgt
     7621 aaaattcaaa ataatgtctc tgtttatgat aatgttcatt tggcagaggg cgtattttgt
     7681 ggccccagca tggtatttac caatgtatat aatccacgct cgctaattga gcgtaaagat
     7741 caatatcgtg ataccttggt aaaaaaaggt gccaccctag gtgctaactg tactatcgtg
     7801 tgtggagtta ctattggtga atatgctttt attggtgcgg gagcagtgat aaataaagat
     7861 gttccagcct atgctctaat ggtaggagtg ccagcccagc aaataggatg gatgagtgaa
     7921 tatggtgaac agttggattt accaatcgaa ggacaagcga aagtaacttg tcctcatact
     7981 ggttcaatat atcagcttaa tggcaagcaa ctacataaaa tttaattttt attaagtcag
     8041 ggattaaaat gcagtttatt gatttagcag cacaacaagc tagaataaag aatgagattg
     8101 atgcggcaat tcaaaatgta ttgcagcatg gggcttatat tttagggcca gagattgctg
     8161 agctagaaca aaagttagct gattttaccg gagcaaagta ttgtattagc gttgctaatg
     8221 gtacagatgc actacaaata gctcaaatgg cactgggtat tggcccagga gatgaagtga
     8281 ttactcctgg gtttacttat atcgctacag ctgaaacagt tgcgctgtta ggtgctaagc
     8341 ctgtttatgt cgatgtgtgt ccaaaaacct ataatcttga tccgattaaa ttggaatctg
     8401 ctattacgcc taatacgaag gcgattattc cagtgagtct atatggccag tgcgcagatt
     8461 ttgatacaat taattctatt gctgcaaaac atgatattcc tgtaattgag gatgctgctc
     8521 agagtttcgg agcgagttat aaaggtaaaa agtcatgtaa tttaagtact attgcatgta
     8581 cgagcttttt cccaactaaa ccactgggtt gttatggtga tggtggtgct attttcacta
     8641 atgatgatga attggctctg ataatgcgtc aaatttctcg tcatggccag gaccgtcgat
     8701 atcatcacat tcgagttggt gtaaacagcc gtttggatac cctgcaagct gcgattttat
     8761 taccaaagct taaaattttg catgaagaaa ttgaactaag aaatcgagtg gccaatacct
     8821 atactcactt attaaatgag gctggtattc tctcaacgcc atgtgtggaa gaacataata
     8881 tatcggcttg ggcgcaatat actatccgtg ttaaaaatag atctgaagtt cagcagaagc
     8941 tgcaagaggc tggcattcct actgcggtac attatcctat tccgttgaat aaacagcctg
     9001 cggttgctga taactgtatt cagttaccta taggtgatga aatcgcccaa gaagttatga
     9061 gtttacctat gcatccatat ttgacagagg aagagattaa acgagtagtc gatagtttgg
     9121 ctcaatgagc tctgttcttc atcgtaaggg tattcaaggt ctaagagcca tagcggtact
     9181 tgccgttatg gtttttcact taaacccgaa ttggctcccg ccggctttat tggtgttgac
     9241 gtttttctgg tgatctctgg cctttgatta ccagcatttt gctgcataaa aaatcaagag
     9301 cagattttag ttttactgaa gcgataaaat atttctatat gatccgtttt atgcggatag
     9361 ctcccgcgta ttttgtgatg ctgatagtgg tatcgttact ggcagcagtt ttgtttctac
     9421 taagtgattt caacacgttt cgaaaagggg aggggaagcg gcttggttta cagtaaccga
     9481 gatactgcta ttttgtaggg tttagggtag tgaatccaac ttaggggtaa tgattcatta
     9541 cctgatacca accgataacc ttatcgtccg ttttttctga ttttgagaag caaattgcct
     9601 ttagagtaag ccgtttaaga tgagtgcgca gattcagatt atggtgctat attcgttgag
     9661 tatatttttt gcagactaca tggtgagctg agttcagctt cgttttgtat atcggctaag
     9721 catcggtcat gtagagacca atattatcaa atttactcaa taacgttaca atccattgta
     9781 acttcagcgc atttcgaggg catcaaagat gcgagcaaga atccgttttc gggtacgatc
     9841 ataagcataa aagagcccgt atgggttact cttacaacgt acgaatgacc actgttcgtc
     9901 agcttcacag ctgataacga ctttggttcc tgactcaacg tgttgtgcta tttgtttagg
     9961 ttccagtttt tttagatagc agcgtatcat gttgacgctg atattaaggg ctagtgctgt
    10021 gccgcgacac tcgggtccgt tcattgctat atcaataatg gattgatgga tattgggttt
    10081 agctgtattg aaagctgagc gactgatgtc gagtgacaat tacggataac atcttagatt
    10141 ttagatctac gaggaaaact atatcaatct tcgctattta ttatccaaac tattaatgat
    10201 acataaacac taagttggag tcatcagctg atagtagata ataaatttgg ttgatttcat
    10261 gtgataaatt tgtcttctag aggaaagtaa aatattaatg atattagata gggttttata
    10321 gcatgattat gtttataacc aaaaacacat tctttaggca gattattttg ctagcgggcg
    10381 gaactgctgc tgctcagttg ataaatctag caatcttgcc aatattaaca cgcatttata
    10441 cgcccagtga ttttggtatt tttgcagtta tgtcggcatc tgtcgctatt gttaatgtat
    10501 ttttgagtat gcgctacgag aacgcaatta ttgcggttaa aactgatgct gatgcattag
    10561 ttggtacatt ttcggtgatg gtattggctt gtgttgtttc tttggcactt gtttttttct
    10621 ggagtgttat tggtttcggg gtagaattaa atactaaata cttgttaata ggttacattg
    10681 ttatcgtttt ttcactggta acttgtttta ctcaagcgtt gtatttttta tgtaatcgcc
    10741 tatcaaatta tcatgtaatg actaatggtc ggatatatgg agctctatca ttagcggtat
    10801 tgtctatatc ttggggatat tttttacata acttctgggg gcttttacta gggtcgttgt
    10861 taggtgtttc tattaatttt ttatatttgt ggtgttcact tggagaaact aaaaataaat
    10921 tgttcactcc taataaaaag gtcgtgaaat atttaaaaga taacattaga tttcctaagt
    10981 atttggtggt ttcaagtctt attgatcgtt caggatctca agggtattta attctactta
    11041 cgaagttata tggtgaggga gtggctgggt cactatctct atataataga gttgctggct
    11101 tcccaagtgt tttagtaggt actgctatag gtgatgtgtt caaaagaaat gcaagtgagc
    11161 agcttcgtaa atatggagag tgtaagagac tagttcttct tactgcggca ggtcttctgg
    11221 tcatagcaat tattcctttc tttcttttat tattttttgg gccacatatt tttgaggttg
    11281 tttttggtag tgaatggcgg caggcaggtg agttcgctag atttcttgca ccggtgtttc
    11341 tattaggttt tatagtgagc ccgatatcaa gtttgatata tttggaggaa aatcaaaaat
    11401 atgacctcta tgtgcagtct atcttgctga tatttttaat attggggctt ggtttctctt
    11461 tgtttttttc taaagtatat tttgctatta tagcgtacgc aatatcatat ttttttaaat
    11521 attgctttga attgaaagtt tgttggagga tagcaagcgg tgagagatga aatgacagga
    11581 ttagatagtt atcaagtttg ctctttctgt gtcatggata cgacagaccc tgaaattaca
    11641 tttgatgaaa atggccgatg taatcattgt gttgcggctg aaaaaaaact agctgaaaac
    11701 tggtttccta atgagaacgg agaaaaaaag cttaaagcta tagctgaaga aattaaaaga
    11761 aataagggaa gtaaagaata cgattcaata attggtatca gtggtggcat tgacagttct
    11821 tatcttttac atctcgcaaa agtagaaatg aatttaaatc cactggttgt tcatgtagat
    11881 gctggttgga attctgaaat tgcagtaaat aatatagaga agatggtgaa aaaactagat
    11941 cttgacttat ttacttatgt tgttgattgg catgaaatgc gagatcttca ggttgcttat
    12001 ttgaaatcat ctttagctaa tcaagatgta ccacaagatc atgctttttt tgctaagttg
    12061 tatcaaatag cagatgaaaa taatatatct tatacaatta caggcagcaa cctaactagt
    12121 gagtctatct tgccagcatc atggggttat gatgctagtg atagcattca aattaaagct
    12181 gtgtttgata aatttggtca gggaacatta aaaaattatc cgataatgtc atggtggaag
    12241 aataaaattt attggccgta tcttcggaga atgaaaatta ttcgcccact taacttcatt
    12301 gattataaca agaatgaggc tattcgtttt ttacagatta actatgactg gcagtattat
    12361 ggcggtaaac atcacgagtc taagtggacg aaatttttcc aggcgcatta tttgcctaaa
    12421 aaatttggat ttgataaacg taaagcacat ttgtctagca tgattgtggc tggtcagatt
    12481 actcgagatg aagctttaaa agaattatca aagccattat ataatgagcg tgacttaaaa
    12541 gaagatatgt tttttattga aaaaaaatta aatctcgaag agggtatgtt agttaagcta
    12601 atgcagcttc caaacaaatc ttatatggat tatcctaatg atcgtaagat tattggctta
    12661 tttagaagta tgaaaagaat ctttttgaga aagtaatttt atttatccag agtatatatc
    12721 ttcttatcga atatatatac tcttggcgat tattaaaaac actgtttagc tttagactag
    12781 aattttcatt gtttatatgg ggcaccgaaa actttttatg gtgatgcctc caattggttg
    12841 aattcgatgt ataatgttcg tcttgaggtt gatccatagt cagcattatc gttcattgtc
    12901 cccgttgtca gtctgctctg gtttattgtc atgggcagaa ccagaaagga catgaccggt
    12961 tccgctgctg aggctgccac cgcgtgtttc aactcgatta ctcatccgag gctcgtaagc
    13021 tggggattaa agagcaaatc atggatggtt ttcaacggtg cgggagttcg cgataccgct
    13081 aggacactga aagtaggtat caataccgtc atccggactt taaaaactct agccacgacg
    13141 aataacatcc tctccggtgg ctcatgctga tgtggcgctt atttgtgagc ttgacgaaca
    13201 atggaacttt atcggtagca aggcacaaca gacctggctc tggtacgcgt acaacacaaa
    13261 aacgggtggt gtactagtct acacttttgg tccacgaacc gatgtaacct gccgtaaatt
    13321 actgactctg ctcactccct ttaacatcgg tatgctaact acagttaatg gggctgctgc
    13381 cagagagttt tctaaagaga agcacttgag cggcaagatc tttactcagc gtattgagcg
    13441 caacaatcta actctaagaa ctcgaatcaa gcgtctagtt cgtagaacca tttgcttctc
    13501 ccgctctgtt gaacttcatg aaaaaggcat tggggctttt atcggaaaat atatgttcta
    13561 ctaattggat gcatcactaa attttcttta atgtcgtaga acagtaatga ggctgatccc
    13621 gagaacttat gcggtatcgc gacatccaga accattcatc gccatattaa caatggtttg
    13681 gtgagtgtct ggtttaacac cagaatagca aaaattgagt tgaaaagtct ttgattagtg
    13741 ctttgcagat ataacattgg ataccggacg ctgaatgtcc gttacatcgc acgccctgaa
    13801 ttttattgca cagaggactg acgacatcga attttgccat agactatatt cgaaagataa
    13861 tatatgcatc atcagcaagt tttcatcatg acctgatttg atgatggtag gctagaagaa
    13921 gatgattgag taaaatctgc tgtcatattc gtgatacctt tatcatatac ctgtattttt
    13981 aaaactgttt ttgcttgtgg cggagtcttt gagacgtgat ttatgggatt atttaaatta
    14041 gggaaatcga gattattttt tcttgttttg gctcttcagc tagccttatt gttaatttat
    14101 ctaaacgata acattgtaaa tgtaggcgaa atgatgggga cgggattgtc ttttttagca
    14161 ttttatatat ttttttttgt tattgttgtt tttagccttt tgttaaatag aagaatatac
    14221 ttacgatttc atttttttat attcatgctt ctgatttttt ggatttccta tcggacaatt
    14281 aatgaccttg gtgatatgga atatctgaag caaattacga tagcaacaac aggcggtatg
    14341 ttatttttct atatattagg agcttcgatt agagtttgtt attgcgactc atatactaac
    14401 aagggtgatg tttttttatc aaaggttgct ttgattgttt tttttatgct ccagctatgg
    14461 atgctgtaca aattctcatt taggcttcgt tccgatatat tctatcttgt tggtgttaat
    14521 ggattatatc aaagggccgg aaactttctc tcaatttcat ttattattgt ttctttttac
    14581 tatttgcaat taatgctgaa tagagttaat aaatatatat ccatatcgtt gtttttttgg
    14641 cttgtaatat acacagtttc aacattaata gcgcttgtag gttcacagat gtttggctca
    14701 aatagtgcta ctggcgttat acttgggata tatgtagtca cattaatgat gactcttatt
    14761 atatcacaga agtcattatg gattaattac ataaatgggc gattagcatt gccattttct
    14821 aaagaaataa taattaaaat gtgctttatg gctcttattg cttttgtgtt tttgatgatt
    14881 attctagtgc ttgtcattgt aatttcagga tttaatgtca acagtttgcg acttgttggt
    14941 tttggcttag atacaaatac ttcgttgttg agtcggatta aaatattgtt agatttaggc
    15001 gaaactcagc taagttatgc accttttttc ggaaatatga atgttgctta tttaactgta
    15061 ggggatgctg gactttttct gcatagtttc ttcccttatg tgatggctaa tttagggatt
    15121 gttggtttgt ggtgtacact ggtattattt attagcttgc tattgcaact ttaccgtgag
    15181 ggtaagtcag gtgaaaccat tgggttatat gatttccaaa ttagtatagt cgcaatatat
    15241 tcttttttga tttttttcta tattcttttt tttgcaaata tgactacgag tatctcttgg
    15301 cctgtcctct ggttcacgtt tggtttcata tccaaaccat tgggttttaa ataatgaaaa
    15361 atatacacat aacactaacg gagtttcgta atgaatctcg tgtgcttaaa gaaatatcat
    15421 ctcttgagac atcaagagtc tttgactctt ttactgttat ttctctaggt gcagatgacc
    15481 tatccaaaga agaggttatt aattcaaaag caaaaataca aagggtaaat ttaatatcac
    15541 gtaagttgcc aaaaagttca ttttttcaga tgataaaatt cattgagttt atatttaaaa
    15601 gttttttgat aataaaaaat gaaaatcctg acgttgttaa tgtgcatact ctttcgctat
    15661 taccgtttgg atggttatta aaaaaaacac taaatgtaaa gttagtttat gatgctcatg
    15721 agcttgaaac tgaaaagaat ggtcttcatg gtgttcgtca acgcatttca aaatggatag
    15781 aagttaactt tatttacttt tgcgatttga taattgttgt tggagataat attgccgatt
    15841 ggtatgcaaa cacttataat attcagcggc cacttgtggt aaaaaattct ccaagggcta
    15901 ttttaaagtc taaggagaat ttgtttcgtg aaaattttgg cattctacag gaacaaaaaa
    15961 taattcttta tcaaggtggg ttgattaaag gtcgtggtat tgagctaata atcgaagctt
    16021 ttgaagctag gattgatact agtgcagttg ttgtttttat ggggtacggt gagctagaac
    16081 atttagttaa gcaagcagca gagaaaaatg aaaatatttt ttactttcct gcggttcatc
    16141 ctagcattgt attagagtat acagcttctg ctgatattgg tatctcttta attgaaccta
    16201 catgtttgtc ttattacttt tgtatgccaa ataagctttt tgaatatgca atggttggtt
    16261 tgccagtaat agtctctaat atgaaagaaa tggcggactc tgtgctggga gctaatttcg
    16321 gtacggtttt gtcaaattat tcaattgaag atattaatgc cgctattgat aatttaatta
    16381 agcatgattt ttctgaactc tctgaaaatg caagagcttt cgcaaaagct cactcatggg
    16441 agcagcaaga agccgtaatg attgaaggat accttaggat tttagggcaa tgattaaaat
    16501 acttgattat ggtatgggta actgtggttc tatcaaaaat atgctacgct accttggtac
    16561 agatgctgag atcgttaatc aaccgaataa attagaaggt gctactggta tcattcttcc
    16621 tggtgttggc tcttacgatc acggcgttaa acacttggag ccatttaagg ctatactaga
    16681 acagaaggtc ttgtatgaaa aaataccttt cttagggatc tgtcttggca tgcagctcct
    16741 gcttgaaaaa agcgaagagg gtaacctacc aggtttgggg tggattaaag gcgaagttat
    16801 gcgtttcgac ttttctatgc taagcaatga acaacaccac gttgtacctc atatgggctg
    16861 gaatgaagtt agtcctgtgg atgcttctga aattttaaaa ccatttgaag taggtcgtcg
    16921 agatcgcttt tattttgtgc attcatatca tgcggctaat gtaccaagtg agaatcagtt
    16981 ggctatctgt cactatggtt atgattttac ttgtgccata cgcgccaata atatcttcgg
    17041 tgttcagttt catccggaga aaagccataa gtttggcaag cagcttttca aacagtttat
    17101 agggttggtg aaatgttaag aaagcgtgtc attccagttt tattgttgcg agatggtggc
    17161 ttggttaaag gcgaaaaatt caaaaagcat aagtatgtag gtgatcctat taatgcggta
    17221 agaattttca acgaaaaaga agtcgatgaa ttggtctttg ttgatatttc tgttggtttt
    17281 agtggtaatg aacctgacta tgagttaatt ggaaacatgg cttctgaagc ctttatgcca
    17341 attgcttatg gtggaggtat tcggagtgtt gatcaggttg agaaattatt tcgacttgga
    17401 attgaaaaag taattataaa cagtgagttt cataacaatc ccgaactagt taaggaatgt
    17461 agccaaatag ctggtgctca aagtattgta gttgcgattg atgttaaaaa aagtctattt
    17521 ggccgttatg aagtttatac acataatggt acttataaaa caggtgtttg tcccgtcgaa
    17581 tatgcaaaaa aggcacaggt atatggcgct ggtgaaattg tattaacatc gattgatcgc
    17641 gaaggatcag ctcagggact ggatcttgac ttaattaaaa aggtcactgc agctgtggaa
    17701 ataccggtga ttgtgcaagg tggtgttggt catttagagc acataaagca ggccgttaaa
    17761 aattctggtg cctctgcagt tgctgcgggg tctttcttta cttttcatgg taagcataaa
    17821 gcagtattac ttacttatcc tgcttacgaa gaacttgaag atttattttt atattgagat
    17881 tgagattgta tggtggattg taattaccaa atgtgtactc gttgtgtaat ggacacaaca
    17941 gatcctgaaa tcatattcga cgcacttggc atctgtaatc attgccatga attcgataat
    18001 gtaactagta agcgctggtt tcctaacgat gatggaaaag caaaattaaa gcagatcttc
    18061 aataagataa aggcagaacg gaaagactat gagtacgact gtattcttgg tttaagtggt
    18121 ggtctggata gtgcgtatct tgcactggta atgaaagagt acggaatgcg gccattggtt
    18181 gttcatatcg atgctggctg gaatagtgag ttggctgtct ataatattga aaaggtagtt
    18241 aagtattgtg gctatgattt gcatacccat gttatgaatt ggcctgaaat acgtgatttg
    18301 caattagcat atttgaaagc gggggttgcg aatcaggatg ttgtccaaga tcatgctttt
    18361 tttgcttcgc tttaccattt tgcggttgaa aaaaaaatcg actatgtcat tagtggtggc
    18421 aatatcgcaa ctgaggctgt ttttcctcag agttggcacc atgccgcaat ggatgctgtt
    18481 aaccttaaag cgattcataa acggtttggt aagctgcaat tgaaagatta taaggtgatc
    18541 agcttcttac agtattactt ctattatcct tttattaaaa agatgaaaac cgttagacca
    18601 cttaattata ttccatactc aaaagaggtg gctcttgcgg agttgcaaga aaaagtaggt
    18661 tacaaacctt atgggcgtaa acatggtgaa tcacgtttca ccaagttttt tcagaatcac
    18721 tatttaccaa ctaagtttaa tatggataaa cgtaagccac atttatcaag tatggtgtta
    18781 tctggcttaa tgtcacgaga gcaggcgctg gaagagttat ctaagccgct ttatgataaa
    18841 aatgagttac gtgaagataa gcattatatt gctaagaagc taggcattac tgttgaacag
    18901 cttaatgaat atgttacttc tccaggccat gattactcag aatacccaaa ttgggattcc
    18961 cgttatgcat ttatgaaaaa agctcagtct tttgtatcca aggtcttagg tcgtaatgtc
    19021 aaaaactact cgtaaaatcg cccacctaac ctctgtccac cctcgctttg atactcgcat
    19081 ttttctaaaa gaatgcatgt ctcttgctaa cagcggctat tcagtttctc tagtcgttgc
    19141 tgatggtaag ggcgacgaaa ctagaaacaa tgtgtctatc tatgatgtag gtgcatctaa
    19201 aggacgttta gatcgcattc ataatgctcc tggtcgtgta ttagctaaag cattagagtt
    19261 ggatgcagat atttatcagc tgcatgatcc tgaattgatc cctattggtg tcaaacttaa
    19321 aaagcatggc aaggtggtga tttttgatgc tcatgaagat gtacctaagc agttgttggg
    19381 gaagccttat ctaaataagc ctgccaagtg gttgctgtca aaaatttttt ccgtgtatga
    19441 gcgctgggcc tgtcgtaagt tggatgcggt gattacggct accccttaca tccgcgacaa
    19501 attcattgcg atgggggtgc gttcggtgga tataaacaac tatccactat tagatgagct
    19561 ttccacagat aaggtggatt ggtcgcagaa aaaagcacag gtcggctatg tgggcggctt
    19621 ggggcgaatt cgtggtattc acgagatggt tcaagcgatg gcattggttg aatctgatgt
    19681 ccgctttgcg gtgggtggca gtttctctga agccagcttt gaacaggcag tgaaagccga
    19741 agcaggatgg gtgaaaactg atcaccttgg ttggttagat cgtacagggg ttaaacaagt
    19801 gttgaatgac tccgttgccg gtctggttac tttgcatccg gtgatcaact atctcgactc
    19861 tttgcctgtc aaaatgttcg agtatatggc ggcgggttta ccggttattg cttcgaattt
    19921 ttctctatgg aaagaaatta tagaaggaaa tcagtgtgga ttatgtgttg atccactggc
    19981 tcctcaagcg atagcagaag cgattgatta cctcgttact catcctgttg aggctgaaca
    20041 gatgggacga catggacaaa aagccgtgca tgaaaaatac aactggtgta ttgaagagca
    20101 gaagttgctt caattttaca aaaccctata agtgataagt atgcaaagaa ttcttactat
    20161 cataggcgca cgaccgcagt ttattaaagc tagcgttgta tcgcgcgcta ttcagcaaac
    20221 cgacggtatt gaagaaatta tcctgcacac ggggcagcat tttgatgcca atatgtcgga
    20281 tatcttttca accaactgaa tattccacgg ccacatattc agttagatat tcacggtggt
    20341 agccatggtc aaatgatagg tcgtatgctt acagaaattg agcaggcttt gttaacccat
    20401 aaaccagatc gcgtgttggt gtatggcgat actaactcaa cactagcagg tgcgcttgct
    20461 gcagcaaaac tgcatattcc cgtggcacac gttgaagcag gctttcgcag ctttaatatg
    20521 caaattccgg aatagattaa tcgtatcctc accgatcaag tgagtgactt acttttctgc
    20581 ccaacgtata cggcagtgca aaatctgaat aacgaaggct ttgcaaacaa gcaggtacag
    20641 ggattgcaag ttggcgacgt aatgcaggat gcggtgctct tatttgccaa aaaagcggtt
    20701 gcaccagcag gtgagctgtc agatgagttt attttggcta cgttacatcg tgctgaaaac
    20761 acagatagcc ccgagcgctt ggcgaatatt gtgaatgcac tgaatcaact tcatcagact
    20821 ttagtacctg ttgtactccc tttacaccca cggacgcgca aactgatcgc cgaacaaggt
    20881 cttgagttga acgttcaatt gactgatccc gtcggttatt ttgagatggt ttggctacta
    20941 gatcactgcc agttggtact gacagatagc ggcggtgtgc agaaagaagc gttttctttg
    21001 gtaaggcttg tgtcacgatg cgtgaccaaa ccgagagctg ataaaagcgg aagctaatgg
    21061 gttagttggt gctgacatta caaagattat tgaaaccgct actcgtaatc ttggacagaa
    21121 aatccaagat acacataatc tgtatggtgg cgggaaagct gcgcagcaga ttgtggatgt
    21181 tatcctgaag gctagtatat gagtaaaaca gtttggattg tacaacagta cgcgtctacc
    21241 ccggcaacgg ggattggagg gcgccattat tacttagggc gtgaactagt aaaacagggg
    21301 tataaggtat atttgattgc ttctgcttca caccatctgt tacgtgaaaa gccagtttta
    21361 aatcagcaat ttaaaataga aacgctggaa aaaggttttt attttgtgtg ggttaatatg
    21421 cctgcttatg cagaagcaca tagcaagcaa cgggctttga attggttttt attcccttgg
    21481 cagattcaaa aattggcacg aaaaattgct gataagccgg atactgtttt atcttcttct
    21541 ccctcactta ttgctttttt aggagctcaa cgactggcta aaaaattcaa agcccgtttg
    21601 gtttttgagg tacgcgatat ctggcctttg accttgactg aaattggtgg ttattcacct
    21661 aagcatcctt ttattcgtgt gatgcagtgg gtggaagata aagcctatcg tgactctgat
    21721 gcgattgtat ctaatcttaa aaattctgtt gaacatatgg ctagccgtgg tatggcgcgt
    21781 gataaattca gttgggtgcc taatgggttc tctttagatg aagtgaataa aaaaatccca
    21841 cttaataata ctgcagccac tcagcttcca aaaaataaat ttatcattgg ctatacaggt
    21901 acgttgggcg tggctaacgc gttgcatacg ctaattgaag ctgctgagcg attgcaggaa
    21961 tatactgaga ttgccttcgt gttagtgggt gcgggaaaag agaaatccgc tctccagtct
    22021 ttagttgtag agaaacaatt gcgtaatata ttctttattg accccattcc taaagttgaa
    22081 atccagtcaa tgttggctga gtttgatgct tgttatatcg gctggttgaa tgatggactt
    22141 taccgttttg gaattggtgc taacaaaatt cctgaatatc tttattcagg taagccggtt
    22201 cttcatgctt actctggtgc ttgtgatccg attaaagaag ccaaggcagg tctgcaagtg
    22261 agagctcaag attcagagca actggctgat gcagtcttaa gtctttatca gatgccagaa
    22321 gaggaaaggc tagctatggg tgaaagtggc cgtaaagctg cacttaagca gtatgagtat
    22381 gggcaactgg ctaatcaatt gataaaagtg ttgtttaact aagtgccttc tgacaaggta
    22441 atctcatgag catccttgac tttaaaggta catgctttca gagaaaaatc atcaacatgc
    22501 ctatgtttaa agagtgaact ctatagattt gttgttctgt tggataacat tatcacacaa
    22561 caaacaatta accgatgatc attttcagag ttttctaata tctctataga caaattgaag
    22621 gtcaaacgat gagtagccag cactcattta tgcatgttga cgccacccca gattaccctt
    22681 agtaccaagt ttgacgtgaa acgacattga aggcgactat taaacataaa agggggatgg
    22741 atctagagta ctttttgaag gttctgagaa gcctttattt acgagaatgc tcatgatttt
    22801 cccgtggtaa tattggtctc tgtggttatc attaacgcgt aacggaacta aaactcatgc
    22861 ttatgatgga ttccatgcga tttataatgc tctatcagag tgtttgtaaa aaaatatatt
    22921 taagaagttc tgtaatgttt atggcatata tcgtgaaatt aaaacatcaa gaatgaagtc
    22981 tttttcctat tatgtggttc actcttataa ttttttgttt aggaggtaaa gttcatgagc
    23041 attgctgtaa cgggggggac gggatttgtt ggtactgtat tagtcaataa actgaagcaa
    23101 cgaaatgtca ggttgataca aaggcgtaaa gttgaattga tatcttcaat tcatagttgt
    23161 catcttcatg aaatatcgtc tagtactcaa tttggcgatt gcttaaagtc ttgcgatgtt
    23221 gtgattcact ctgctgcact agtgcacgtg atgactgata gtgtaagtaa gccattggaa
    23281 gcatacagag aagttaacac gttgggtaca gccaacctag cacgtcaagc tgccctgtca
    23341 ggggtaaagc gttttatttt tattagtagc attaaagtta acggcgagaa aacgtgcaca
    23401 aataaccaat ttacctctgc tgatgaacat gccccagaag atgactatgg gctatcaaag
    23461 tctaaggcgg aacagcatct ctttgatata ggtaaaaaga caggaatgga aatcgtggtc
    23521 attaggccaa cacttgtcta cggtcctgga gtaaaagcta atttttcctc tttgatgaac
    23581 ttagtttcaa aaggtattcc actgccattt ggttgtatca ccaagaacaa gcgcagtttg
    23641 gtttctgtag ataatttggt cgatctcatt gttacttgta ttgaccatcc gaaagcggct
    23701 aatcaagtct ttctcgtttc tgatgatcgt gatgtttcta cgtctgaaat ggtacgtgaa
    23761 atggctatag ctttaggtaa aaccacctgg cagctccccg taccaatttg gtgttacaag
    23821 ttaataggta aattattcaa caagtcagat attgtagata ggttaattgg gtcattgcag
    23881 gttgatatct ctcatactaa aaatacatta ggttggaagc ctcctcagac tctgcaggat
    23941 ggctttaaac aaacagcaca agcctttctt caagcaaaca gaaaatgatg gtaaaaatga
    24001 ttcgcttaat tgatcttttc gctgcattct ttggcttact actcctatgg ccagtcttat
    24061 taattgttac cctggttggt atttttgata ccggttcgcc gattttcgtt caggagcgtg
    24121 ttgggcgtca caaaaaacca tttaagctga ttaagtttcg cactatgtcg ttggatacgc
    24181 aatctgttgc atctcatcta gcaagtgcta gctcaatcac taagctcggt gcttttttgc
    24241 gtaaaactaa gattgatgag ttgccacaat tgattaatgt gttgaaaggt gaaatgagct
    24301 tagtaggacc tcgccctaac ctttttaatc agctcgagtt aattgctgaa cgtgatgtct
    24361 tgggagtata tgatgtactt cccggtatta ctgggctggc tcaaatcaat aacattgata
    24421 tgtctacacc aaagttatta gccgaaacag ataagaaaat gattgatacg cttaccttgt
    24481 caaactattt caaatatata attaaaaccg tatcagggag tggagctgga gatgcaatag
    24541 ctaagggcta attttcaatt atttagtata gctgagcatg gtaatgctag ttaagtctat
    24601 gatggacttt atcttaatgt taagagaact attatgttgg cacgcttact gggtttatca
    24661 aggggactta aacgcagcat catgctgacc atcgatgttg ttttgttggc tttttcatat
    24721 tggggcgcgt tttgggttcg cttagatgat caaacaccac tgacagctat agagaattgg
    24781 cagttatttg catttcttgc cgtttgtaca attttatttt ttatccgaat tgggctttat
    24841 cgcgcggtat tgcgatatgt gagtgcgaag gtcattggta ctgttgcgat aggcattagt
    24901 ttctcgacag tgttattggt gatttccgcc tacttctctg gtgttttttt accacgcacg
    24961 gttgcagtaa tatattttac tttttcgctt ttatttatct gcggctctcg cttggcattt
    25021 agaatgatgc tgagctatgg tgtacgtggt caattacctg ttatcattta tggtgctggt
    25081 gcgtctggtc gtcaattgct tccggcgttg gctcaagtaa gtgaatattt tccagtggca
    25141 tttgtggatg ataatcctcg cttgcataag gctgtcattc atggagtaac agtttattcc
    25201 tcggataaac tgaattatct agtagatcgc tatggtataa agaaaattct tttggcgatg
    25261 ccgagtgtta gcaagtcgca aaggcagaaa gtgattgctc gtttagagca tttaccgtgt
    25321 gaagttctct ctattccggg catggtcgat ttagttgaag gtcgagctca aatcagtaat
    25381 ctcaaaaaag tatcgattga tgatttgcta ggtcgtgatc cagttgctcc tgatgccaaa
    25441 ttgatggccg aaaacattac tggcaaagcg gttatggtca ctggggcggg aggctcgatc
    25501 ggctctgagc tttgtcgtca aattgttcga tataagccgg ccaaattggt tctatttgag
    25561 ctgtctgaat atgccctcta cgccattgag aaagagctct cgacgctgtg tgataaagag
    25621 ggtttggatg ttgcagtagt tcctcttttg ggctcggtgc agcgtcagaa tcgcttacag
    25681 atggtgatga aatcctttgg tatccaaacg gtttatcatg cggccgctta taaacatgtg
    25741 cctctggttg agcacaatgt ggtggaaggg gtacgtaata atgtgtttgg taccttgtac
    25801 tgcgctgagt cagcgatcga aagtggcgtt gaaacttttg tgttgatttc tacggataaa
    25861 gcggtgcgcc cgactaacac tatggggaca actaagcgtc tggctgagtt ggtattgcag
    25921 gctttgtcag tacggcaaag ccaaacccgt ttttgtatgg tgcgatttgg taatgtgctg
    25981 ggctcctctg gctcagtcgt gccgttgttt gaaaagcaga ttgcccaagg tgggccagtt
    26041 accctgactc atcgtgacat tattcgctat tttatgacaa ttccggaagc atcgcagttg
    26101 gtgattcaag cgggggcgat ggggcatggc ggcgatgtct ttgtcttaga catgggagat
    26161 ccggttaaga tttatgactt agccaaacgc atgatccggt taagtggctt gagtgtacgg
    26221 gatgataaaa atccagatgg cgatattgcc attgaagtta cgggattacg tccaggtgag
    26281 aaactgtatg aagaattact gattggtgat tcagttcaag gtacctctca tccacgaatt
    26341 atgacggcca acgaagtgat gctaccgtgg caggatctat cgctcttact taaagagctg
    26401 gatcaagcct gtcatgactt tgatcatgag cgcattcgca gcttattgtt acaagcacca
    26461 gcggcattca atccaactga tgatatttgc gatctagttt ggcagcagaa aaaatcgctg
    26521 ttatcacaag cgagcaatgt cattcgcctg tgattgctta ggtttaacct ttcacaccaa
    26581 tccttcacct ctcttacaaa tccccgctag gcggtacatc gtgaccgcct ttaccctgat
    26641 gtctgctctt taacaaacag gacatcagtg tatgtttaaa ccttttagcg ccgaattttt
    26701 cggtactttc tggctggttc tgggggctgt ggtagcgcct tgatctctgc tgctttccct
    26761 cagttaggca ttggcttttt gggcgtggcg ttggcttttg gtctgacagt agtcaccatg
    26821 gcttatgcgg tcgggcacat ctccggagcg cattttaacc ccgcggtgac cttgggtctg
    26881 tgggccggtg gacgcttccc tgcggcgcgc gtgttacctt acattatcgc tcaggttatc
    26941 ggcggtattg ccgctgcggc agtgctgtat ggtatcgcca gcggtaaggc tgggtttgat
    27001 gcgacaacca gcggctttgc gccattggct attggtctga cgctgactat catccatttg
    27061 gtgagcatcc ctgtcaccaa tacctcggtt aaccctgcgc gcagtatcgc ggcggcggtt
    27121 ttccaaggta cttgggcgtt agatcagttg tggatgtttt gcctgatccc atcattaggc
    27181 ggaattgccg gtggtctgat ttaccgcgca ttgttggcgc gtccggctga agcataa
//
