LOCUS       MK551190               24898 bp    DNA     linear   BCT 05-MAY-2019
DEFINITION  Plesiomonas shigelloides strain O76H39 putative O antigen gene
            cluster, complete sequence.
ACCESSION   MK551190
VERSION     MK551190.1
KEYWORDS    .
SOURCE      Plesiomonas shigelloides
  ORGANISM  Plesiomonas shigelloides
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacterales incertae sedis; Plesiomonas.
REFERENCE   1  (bases 1 to 24898)
  AUTHORS   Xi,D., Wang,X., Ning,K., Liu,Q., Jing,F., Guo,X. and Cao,B.
  TITLE     O-Antigen Gene Clusters of Plesiomonas shigelloides Serogroups and
            Its Application in Development of a Molecular Serotyping Scheme
  JOURNAL   Front Microbiol 10 (2019) In press
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 24898)
  AUTHORS   Xi,D., Wang,X., Ning,K., Liu,Q., Jing,F., Guo,X. and Cao,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2019) TEDA, Nankai University, Hongda Street 23,
            Tianjin 300457, China
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: VelvetOptimiser v. v2.2
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..24898
                     /organism="Plesiomonas shigelloides"
                     /mol_type="genomic DNA"
                     /strain="O76H39"
                     /db_xref="taxon:703"
     gene            1..1974
                     /gene="rep"
     CDS             1..1974
                     /gene="rep"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase Rep"
                     /protein_id="QCH03311.1"
                     /translation="MLAGAGSGKTRVITNKIAHLIRGCGYQARHIVAVTFTNKAAREM
                     KERVAQTLGRGETKGLLVSTFHSLGLEILKREYKALGLKAGFSLFDDQDQMALLKELT
                     EDSLKGDKDLLSQLVQKISGWKNDMILPEQAKVRAKGERDILFALCYEQYARQLRACN
                     VLDFDDLILLPTLLLRTQEEVRERWQNRIRYLLVDEYQDTNTSQYELVKLLVGARARF
                     TVVGDDDQSIYSWRGARPQNLTLLRQDFPALKVIKLEQNYRSSQRILKSANILIANNP
                     HEFEKQLFSELGPGEMLRVLQANNEEHEAERVVGEIIAHRFLNKTQYKDYAILYRGNH
                     QSRTLEKMLMQNRIPYKISGGTSFFARAEIKDIMAYLRLLINPDDDTAFLRVVNTPRR
                     EIGPVTLEKLGTWAHSRGNSLFAASFDLGLKQHLQGRGLEALRQFTRWITEIADRAQR
                     GDPVAALRDLVHGIHYESWLYETSASPKAAEMRMRNVSTLFGWVTEMLEGKDGEEPMT
                     INQVVQRLTLRDMLERGEDDAEADQVQLMTLHASKGLEFPHVFLIGMEEGILPHQTSL
                     DEDNVEEERRLAYVGITRAQKTLTFTLCKERRQYGELLRPEPSRFLHELPQDDLEWEV
                     RKAPVSAEQRQQRGRQGVAGLREMLAQAKKRPE"
     misc_feature    1..24898
                     /note="putative O antigen gene cluster"
     gene            complement(2129..2539)
                     /gene="rfaH"
     CDS             complement(2129..2539)
                     /gene="rfaH"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription/translation regulatory transformer
                     protein RfaH"
                     /protein_id="QCH03312.1"
                     /translation="MQDIRYFCPMLTVKKQRRGKTQEESEALFANYLFVHFNPDQLSV
                     TRVQATRGVARLVRFGETLARVPDEVLIDLARRYNPLVALPEEGKVCSQPMCTALQQA
                     LADIERESNGEVRALRFLQLLQDHRLLASRHRVE"
     gene            complement(2895..3221)
                     /gene="c5"
     CDS             complement(2895..3221)
                     /gene="c5"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c5"
                     /protein_id="QCH03313.1"
                     /translation="MSDDAISERIKPVSGVYLADAAATAKPSGPRTGEQVYNGACIAC
                     HGSGALGAPKFRDAAQWAPRLKQGIDTLQKHAIAGLNQMPARGTCTDCSDDEIKAAIE
                     YMTSGL"
     gene            3861..4970
                     /gene="wzz"
     CDS             3861..4970
                     /gene="wzz"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz"
                     /protein_id="QCH03314.1"
                     /translation="MSKASEPQQTPYLIPQGAYPVYMPKAEDEIDLFELLGTLWKKKW
                     VILFVTLLTTGLVAVYAFTAKEQWTAKTYIQAPRIAELGSYLKFRQAYARILNQPLDT
                     NALANGLFSDLILIAESPDTKFKFLENTEYYKKETQSLSSEQAKKIWLTEQANKGLVI
                     TPPKEKENISYYTIQASADSAKEAYTLLQGYLKDVNNQAVTLSLDEFDQNINTLLVSL
                     KKEVNDIDFQKKAEKLDQIAYIQRDLTTAEQAGITDYRSSKNGFDNAQSSYKFLLGEK
                     LLSAELKATKDAPIIYPFRYYEVKRQIDELEGILRDNIQAQAYRYQMVPAEPLKKDKP
                     KKALILVLGALLGGMLGIVSVLINSAITNRKEGLK"
     gene            5865..6290
                     /gene="rmlB"
     CDS             5865..6290
                     /gene="rmlB"
                     /codon_start=1
                     /transl_table=11
                     /product="RmlB"
                     /protein_id="QCH03315.1"
                     /translation="MPIYGKGDQIRDWLYVEDHARALYEVVTAGVVGETYNIGGHNEM
                     QNLDVVHTICDLLDEIVPKADSYRKQITYVADRPSHDRRYAIDASKISCELDWQSEET
                     FESGIRKTAQWYLDNQQWVNNVKNGSYQCWIDQLYGEKK"
     gene            7159..8235
                     /gene="degT"
     CDS             7159..8235
                     /gene="degT"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="QCH03316.1"
                     /translation="MIFLNKPVAPKLAKLNSYLEKINETGWYTNFGPMHQALTERLED
                     YLGVKNLLLVSNGTLAIQVAAKALNISKSITTPFTFVATTSSLLWQGMDVAFSDINSG
                     SLNIATDKLEQIWGNEPSYDSLLAIHVYGNPCDVKKIDELARKYNKKVIYDAAHAFGV
                     NVGSDSVLNFGDASTLSFHATKVFHTVEGGAIVFKNKVDLEKAKNLINFGIGNDGVLG
                     QPGINAKLNEYQAAVGLCILDDIDDILDHRASLFDLYRKELMNVVDMPHWHDDANYNG
                     AYMPICPENETVRLNIGDKLTENNIQFRRYFYPSLDQAYPKVKSFGCPISNVIAENVL
                     CLPLHTYMTAADIYKVTSIIKEVF"
     gene            8965..9909
                     /gene="orf7"
     CDS             8965..9909
                     /gene="orf7"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCH03317.1"
                     /translation="MLLKSAIDSNNCTYPYLFTANARTAWYKILESITASKCKRLKLL
                     LPAYIGINDKEGSGVFDAVLKSQADFVFYKVTDNLQVDIEDFHKKINGESFDLALIIH
                     YFGFSRVNMGDLKSACEINDVILVEDCAHAFYLDDKESKIGAYGDYSFYSLHKYLAVS
                     TGGLLKINNNMLQIPKLSPEDIIDLSALEMFASSDFKRIAEIRRDNYKAYYDKLINND
                     NINILFDLNENDIPQTFPIFVKNGLREKLYFYLLNNNIPTVALYYRMIPQIEPSKFEL
                     SMLISSGILNLPVHQDTTLEDIDLVCSKINYFFGDLHD"
     gene            10364..11869
                     /gene="wzx"
     CDS             10364..11869
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="QCH03318.1"
                     /translation="MLMLRKNILANYISQAYVAVIGILILPLYIQYMGAEVYGLIGFF
                     TLLQAWFGLLDLGLTPTIARETARYHGGSMSALHYRQLFRALSTIFIGIAVIGGVALW
                     LLAKPIAYKWLQVETLSMNVVVVAVQIMAVSVALRWLGGLYRGVITGSERLVWLSGFN
                     AIIATLRFPAVFITMWLYGFTPTVFFWHQLAVAIIEVLGLYLMSNKFKPVLAKSEIIG
                     WSIQPVKPVLKFALAIAFTSSAWVLVTQTDKLILSGILPLAEYGFFTLAVLVASGIMI
                     LSAPVSTVIMPRMTRLHAEGKHDEMIQVYRNATQLVSVVAGSASLTITFFAEPLLYAW
                     TGDKEIASNAAPILTLYALGNGVLAVSAFPYYLQYALGNLRYHLIGNLVIVVTLIPAI
                     IWAASEYGGVGAGWAWLGINSLYLILWVGYVHHKLQPGVHVGWLLKDVLVIYAPVILV
                     LFLASSYMSYQTRQEALLTLVVLSFVAIFVAIVSSSVARKVLNQKLFGVKS"
     gene            11866..12807
                     /gene="gt"
     CDS             11866..12807
                     /gene="gt1"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="QCH03319.1"
                     /translation="MNSDIKVSVCVVTYNQEKYIAECLQSLVDQITDFPFEIIVGEDC
                     STDKTREIVLEFQNKYPNIIKPLLHMENVGPVKNVIATYKQAKGTYIAHMDGDDLALP
                     GKLQVQADVLDENTDCIICSHDVELLTFNGEFLKRTFRKHEKVKNTIFDLYQRLPFFV
                     HSSKMFKNDLDEKFWEQLHPQALDIEVHAQQAKYGNIYHIDKVFGVYRVGVGVSVNAV
                     ASVNPLLVAGNERVFMDALATYNGKTSTLKAYYAKTLMNYAYQSAIFGDKCGYVAYIR
                     KSVSIKLFSAVQAIMFIFSFLPRVAVLISKKRNKIRF"
     gene            12818..14020
                     /gene="wzy"
     CDS             12818..14020
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="QCH03320.1"
                     /translation="MTINPVVSLFCLYLFANFIALVQGINDGGLVLEGYFFELKTTSL
                     VYSFLLQTIILLLLIGLYRFFTTKGNCKKITYGKNWGWFLIIIQMSFLIFNIKTGVNI
                     AGDGARIEGGSVINYVFVLLQPDMLFMLIGTSLLSGRLFLINLIVFLVSMALRGWMGG
                     FFIIIFMVLSRYYPVRISSRSLFCILFLAVLFVLVLPVIIDMKWSMRQGVSVGVFFSS
                     IFNSFSAEKYNLAISYLLNRFQHLGHVALLLENSDKLYFDLSNGLFSSYWMDGLPQHT
                     ISKIFGFEQHKLNSYMVEYFFGIEDPTWNTNPGLAGWVFILQEKVVFMALYLFFVVVA
                     PFYFISRYAGSTMLMLIACFSIVYLFHGWFGAYFNIIFYGLILVVISKLKVTNRSSVE
                     SFTNKAVN"
     gene            14020..15903
                     /gene="wbpS"
     CDS             14020..15903
                     /gene="wbpS"
                     /note="WbpS"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthetase"
                     /protein_id="QCH03321.1"
                     /translation="MCGVSGFLLSRQLSKAEPKSLQCMIAAISYRGPDDSGTWYDENQ
                     GIALGHTRLAIVDLSPAGHQPMASACDRFVIAFNGEIYNHLTLRKQLDSQGAAPVWRG
                     HSDTETLLACFSAWGIEATLKATVGMFALALWDKQDQQLTLARDRLGEKPLYWGWCSD
                     TLLFGSELKALKAHPDFNAGLDRGALSLLLRHNYIPAPYTIYQGIEKLPAGQYVQIKK
                     GQLRADVQLKAYWQLNQSIERGLANPFRGTDTQATDLLEQTISQAVSGQMLSDVPLGA
                     FLSGGIDSSTVVALMQQQSKQPVRTFAIGFDEPGYNEAEYAKEVAQHLGTDHTELYVS
                     AQDALDLVPRLPDIYCEPFADSSQLPTFLVSRMAKQHVTVALSGDGGDELFGGYNPYQ
                     FAPRVWSTLQRLPLPLRQIACRLLSGLPLPDKLEKLLRVLPAKDKEQFYQILMSHWDN
                     PGQLVIGGNEYPILINSTDQWPKTDSFEHWMMAMDAGQYMIDDILVKVDRAAMANSLE
                     TRVPLLDHRVVELAWQLPLHMKIRGGVGKWVLREVLYRHVPREMIERPKKGFSVPLGQ
                     WLRGPLRDWAEALLNKQRLEQEGYFNSIVVRHVWSDHLQGKCDHARKLWGILMFQAWL
                     EKQ"
     gene            15951..17030
                     /gene="gt"
     CDS             15951..17030
                     /gene="gt2"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="QCH03322.1"
                     /translation="MLKRLIESHRERPDIEHSIISLTDMGVLGEQLTKQGVAVYCLGM
                     SSIMKGPVTFFKLRKLLRELRPDVVHTWMYHADLLGALAARSIGLRQIVWCIRSTDIK
                     KGGSKVTLIIRKLCALFSGWLPRVIVCAADASRKVHEAVGYASNKMQVIPNGFELAKL
                     LPTGSNDTHIRDELGISKACRLVVSVGRYNPVKDHKTFIEAAGKVATQRNDVRFMLVG
                     RDLEYSNSQLMALINATGQADTFYLLGERNDVPACLQASDVFCLHSVTEGFPNVLGEA
                     MAVGLPCIATDVGDAAYLLDNPEWVVPAASPSQLADKLDVMLSLSTTDREVLGQTSAN
                     RIREHFTMDVISRRYFDLYTSLIDV"
     gene            17076..18344
                     /gene="vipA"
     CDS             17076..18344
                     /gene="vipA"
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide biosynthesis
                     UDP-N-acetylglucosamine C-6 dehydrogenase TviB"
                     /protein_id="QCH03323.1"
                     /translation="MQNTHIAIIGLGYVGLPLAVEFGKKYPVLGFDINKARLAELSKG
                     HDSTLEVDDHELAEAKHLTFSSSLDDLKACNVFIVTVPTPINKHKQPDLTPLIKASET
                     IGKVLKQGDIVIYESTVYPGATEEDCVPVLERVSGLTFNKDFFCGYSPERINPGDKEH
                     RVTTILKVTSGSTPEVAETVDQLYRSIITAGTHKASSIKVAEAAKVIENTQRDVNIGL
                     INELALIFNRLGIDTEEVLKAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQSVGYH
                     PEIILAGRRLNDGMGAYVASQLVKLMLKKRIQVEGSRVLVLGLTFKENCPDLRNTKVV
                     DIIDELQDYGVSVDCYDPWINATEAQHEYGITPVSEPVAGVYDGIVLAVAHKEFTAMG
                     AEKIRALGKPVHVLYDLKYVLPTSTTDLRL"
     gene            18415..19407
                     /gene="vipB"
     CDS             18415..19407
                     /gene="vipB"
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide biosynthesis
                     UDP-N-acetylglucosaminuronic acid C-4 epimerase TviC"
                     /protein_id="QCH03324.1"
                     /translation="MPAQPKVWLVTGVAGFIGSNLLEHLLKLNQTVVGLDNFATGHQH
                     NLDEVKGLVTAEQWADFTFIEGDICNLDDCQKACIGVDYVLHQAALGSVPRSINDPIT
                     TNATNTSGFLNMLVAARDAGVKSFTYAASSSTYGDHPALPKVEESIGKPLSPYAVTKY
                     VNELYADVFAKTYGFKTIGLRYFNVFGKRQDPNGAYAAVVPKWVASMLLGDDIFINGD
                     GETSRDFCFIENTVQMNLLAATAPDEAKNEVYNVAVGDRTTLNDLFHALQAALEQNNK
                     PYGKTPVYRDFRAGDVRHSQADINKAISKLGYKPEYRIMDGIVKAIPWYIQNVG"
     gene            19507..20550
                     /gene="gt"
     CDS             19507..20550
                     /gene="gt"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="QCH03325.1"
                     /translation="MGYDIHVATADGPEVQSIQSLGFTHHVVPFSRGGQNPLNELKTL
                     ISLIKLFKAIKPSLVHLITIKPVLYGGVAARLTGVEAVVSAVSGLGTVFLAESTIARL
                     RRWLVILMYRLAFNQKRLSVIFQNPDDRDILLSLKALKTHQVRMIRGSGVDLLDYPFL
                     PEPEGTPVVVMAARLLKDKGVFEFIEAAKILNERNTAVEMKLIGAPDLGNPTSVSQTE
                     LDQWAALDFVQLLGYQKNIGKHYSEANIICLPSYREGLPKSLVEAAACGRPVVTTDVP
                     GCRDAITPEKTGFLVPVKNATALADAIEILIQDANLRKSMGQAGRALAEEVFAIEKIV
                     EQHMAIYRELLKI"
     gene            20547..21512
                     /gene="wbhp"
     CDS             20547..21512
                     /gene="wbhp"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="QCH03326.1"
                     /translation="MNIESKVLLTGASGFVGNVLNAAMINNYQVLPVVRDKHSVDFDV
                     CVEVQEIDKNTQWVEALSGVHCIIHCAARVHIMNDSSSDPLAEFRTVNTEGTLNLARQ
                     AVEAGVKRFIFLSSIKVNGESTSNGEPFTAFDLCLPEDPYGMSKFEAEKQLIAIAKDS
                     GMEVVIIRPTLVYGPGVKANFVSLMNLVSKGIPLPFGCITKNKRSLVSVDNLVDLIIT
                     CIDHPKAANQVFLVSDDHDVSTSDMVRELAIALDKPTWQLPLPIWCYKLVGKLFGRSD
                     IVDRLTGTLQVDISHTKETLGWKPPQTLQEGFKKTAQAFLLANNK"
     gene            22816..24078
                     /gene="wbgZ"
     CDS             22816..24078
                     /gene="wbgZ"
                     /codon_start=1
                     /transl_table=11
                     /product="WbgZ"
                     /protein_id="QCH03327.1"
                     /translation="MIARLEHLPCEVLSIPGMVDLVEGRAQISNLKKVSIDDLLGRDP
                     VAPDAKLMAENITGKAVMVTGAGGSIGSELCRQIVRYKPAKLVLFELSEYALYAIEKE
                     LSTLCDKEGLDVAVVPLLGSVQRQNRLQMVMKSFGIQTVYHAAAYKHVPLVEHNVVEG
                     VRNNVFGTLYCAESAIESGVETFVLISTDKAVRPTNTMGTTKRLAELVLQALSARQSK
                     TRFCMVRFGNVLGSSGSVVPLFEKQIAQGGPVTLTHRDIIRYFMTIPEASQLVIQAGA
                     MGHGGDVFVLDMGDPVKIYDLAKRMIRLSGLTVRDDKNPDGDIAIEVTGLRPGEKLYE
                     ELLIGDSVQGTSHPRIMTANEAMLPWQDLSLLLKELDQACHDFDHERIRSLLLQAPAA
                     FNPTDDICDLVWQQKKSLLSQASNVIRL"
     gene            24197..24898
                     /gene="aqpZ"
     CDS             24197..24898
                     /gene="aqpZ"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin Z"
                     /protein_id="QCH03328.1"
                     /translation="MFKPFSAEFFGTFWLVLGGCGSALISAAFPQLGIGFLGVALAFG
                     LTVVTMAYAVGHISGAHFNPAVTLGLWAGGRFPAARVLPYIIAQVIGGIAAAAVLYGI
                     ASGKAGFDATTSGFAANGYGIHSPGGYALSACMLSEFVLSAFFVIVIHGATEKRAPAG
                     FAPLAIGLTLTIIHLVSIPVTNTSVNPARSIAAAVFQGTWALDQLWMFCLIPSLGGIA
                     GGLIYRALLARPAEA"
BASE COUNT     6674 a   4757 c   5882 g   7585 t
ORIGIN
        1 gtgctggctg gcgccggctc gggaaaaacc cgcgtaatta ccaacaaaat tgcccacctg
       61 atccgcggct gcggttatca ggcgcgccac attgtggcgg tgacctttac caacaaagct
      121 gcgcgcgaga tgaaagagcg ggtagcgcag acgcttggtc gtggtgaaac caaaggcttg
      181 ttggtttcca ccttccactc tctgggcttg gaaatcttaa agcgcgaata taaggcgctg
      241 gggctgaaag ccggtttttc gctgtttgac gatcaagacc aaatggcgct gctcaaagag
      301 ctgaccgaag acagcctcaa aggcgataaa gatctcctca gccagttggt gcaaaaaatc
      361 tccggctgga aaaatgacat gatcttgccc gagcaggcca aagtgcgtgc caaaggtgag
      421 cgcgatatct tgtttgccct gtgttatgag cagtatgcac gccagctacg cgcctgcaat
      481 gtgctggatt tcgacgatct gattttgctg ccgaccttat tattgcgcac ccaagaagag
      541 gtgcgagagc gttggcaaaa tcgcattcgc tatttattgg tggatgagta tcaagatacc
      601 aacaccagcc agtacgagct ggtgaaattg ctggtcggcg cgcgcgcccg tttcaccgtg
      661 gtaggggatg atgatcagtc gatttactca tggcgcggtg cgcggccaca gaacttgacc
      721 ttgctgcgcc aggattttcc ggcgttgaaa gtgatcaagc tggagcagaa ctaccgctcc
      781 tcgcagcgga tattaaaatc agccaatatc ctgattgcca acaacccgca tgagtttgaa
      841 aagcagctgt tctcggagct cggccccggt gagatgctgc gtgtgctgca ggctaacaac
      901 gaagagcatg aggctgagcg cgtggtgggt gagatcatcg cgcaccgttt cttgaacaag
      961 acccaatata aagattacgc cattttgtac cgcggtaatc accagtcgcg cacgctggaa
     1021 aagatgctga tgcaaaaccg catcccgtac aagatctcgg gcggcacctc cttctttgct
     1081 cgcgccgaaa tcaaagacat catggcctac ttgcgcctgc tgattaatcc tgatgatgac
     1141 accgcgttcc tgcgcgtcgt gaatacccca cggcgtgaaa tcggtccggt gaccttggaa
     1201 aagctcggta cgtgggcgca cagtcgtggc aatagcctgt ttgccgctag ctttgatttg
     1261 ggattgaagc agcatttgca ggggcgtggc ctggaggctc tgcggcagtt tacacgttgg
     1321 atcaccgaga ttgccgatcg cgctcagcgt ggcgatccag ttgccgcgct gcgtgatttg
     1381 gtgcatggca tccattatga aagctggctc tacgagacct ccgccagccc gaaagcggct
     1441 gagatgcgca tgcgcaacgt ttcgaccttg tttggttggg tgaccgagat gctggaaggg
     1501 aaagacggcg aggagccgat gaccatcaat caggtggtgc aacgcctcac cttgcgcgac
     1561 atgttggagc gcggtgaaga tgacgccgaa gccgatcaag tgcagttaat gacgctacac
     1621 gcctcgaaag gactggagtt tccgcatgtc ttcttaattg ggatggaaga ggggatcttg
     1681 ccgcaccaga ccagtttgga tgaagacaat gtggaagaag agcgccgctt ggcatatgtc
     1741 gggatcactc gcgcccagaa gaccttgacc tttaccctat gtaaagagcg ccgtcagtac
     1801 ggtgagttgt tgcgtccaga gccgagtcgc ttcttgcacg aactgccaca agatgattta
     1861 gagtgggaag tacgcaaggc gccagtcagc gccgaacagc gtcagcagcg tggccgccaa
     1921 ggggtggccg gattacgcga gatgttggcg caggcgaaaa aacggcccga gtgatcttac
     1981 tggccatgcg cttagtgttt acgcatataa gcgtctactc atgtaagtga ctacagagat
     2041 aagtgcctaa ttatttaggc gcttataaat gcggaagagg ctcgcaacgg gcgtgcgcac
     2101 gatgacattg gaatgccgga acgctggatt attcgactcg gtgacgggaa gccaacagac
     2161 gatgatcttg cagtaattgc aaaaagcgta gcgcacgaac ttccccattg ctttcacgct
     2221 cgatatccgc caaggcctgt tgtaaggcgg tacacatcgg ctgactacag actttaccct
     2281 cttccggtag tgcaaccagc gggttgtaac gtcgcgctaa atcgatcagc acctcatccg
     2341 gcactctcgc caacgtttcg ccaaaacgta ccaaccttgc tacgccgcgc gtagcttgca
     2401 ctcgcgtgac actcagctga tcgggattaa agtgcacaaa caggtaattg gcaaacagcg
     2461 cttcgctttc ttcttgtgtc ttaccgcgac gctgcttttt taccgtcagc atcggacaaa
     2521 aatagcggat atcttgcaac tccagatgtt gcgccgcccg actttgctgt ccgcgtttac
     2581 aataaagaag ataccaggcg tccatagata gttttgtgat gaaaataatg actgcagtat
     2641 gccacagagt ggatagccga tcagtctttg ggtgtgatgt aacagtcagt ttaattaatg
     2701 aggggcagca caaagtaccg tttgcgcaaa atatctccgg taaatcgtca gttagagcta
     2761 gttaagtcag agtaatttag cgcaaacaat catgaataga catatatata aaggaggctc
     2821 ctaagcctcc ttttatccat ttgtctattt gcgcggtatt tttctttata tgctaattag
     2881 gcgtgtcgcg tagcttataa cccgctagtc atgtattcga tcgcagcttt gatttcatca
     2941 tcactacaat cggtacaggt tccgcgtgcc ggcatctgat ttaaaccggc gatggcatgc
     3001 ttttgcaggg tatcgatacc ttgcttcaga cgcggcgccc actgcgcggc atcacgaaat
     3061 tttggtgcgc ctaaggctcc gctgccatga caggcgatac aggcgccgtt atacacctgc
     3121 tcacctgtac gcggcccgct cggtttagcg gtggccgcag catcagccag atacaccccg
     3181 ctgaccggct tgatgcgttc gctgatggca tcatccgaca tatcggctgc ggcagcccag
     3241 caggatatgc ctagcagcaa ggaggccagc agagttaacg ccgcctggcg aggcttagcg
     3301 cagatagact tggcacgcac aaagacagtg ttcacagatt ttctccctaa ataaccagcg
     3361 gcatcctttt atcctgcttt cattcttaat cggtctgagc agggctgtga accgcagcgg
     3421 ttgaatattg actactcggt tgtgttgcca gattataagg taatcgtaaa taaattgaag
     3481 caattgcgcg agattctttt tgcaaggcag ccagcgtgcg acagcttgta ccgcctagcc
     3541 tcacagaatt tacaaacata ctgttatctt tttgacggca gatttggcct tccataggca
     3601 ttgctttata atctgcactc caaattctgc gggctatccg ccggtttgca acagggaagt
     3661 gggatgcgac acatgcctct tcacatggag cgttctcgat catgtcctct aatcccagat
     3721 atcactttta tcgtcgttgg cgatatcctg tttttgcgca gcgctttggg agctgaaact
     3781 caagggcggt agcgtgcttt tttgtcagtc ttattcttta tttttattct taacccattg
     3841 ataagtaatg gatttattta atgtcaaaag catctgaacc acaacagact ccttatctga
     3901 tcccacaagg ggcttatcct gtctatatgc caaaagcaga ggatgaaatc gatcttttcg
     3961 agcttttagg caccttgtgg aagaaaaagt gggtgatttt atttgtcaca ttgctgacta
     4021 caggattagt ggcagtgtat gcctttaccg caaaagagca gtggacagca aaaacttata
     4081 ttcaggcacc acgtattgct gaactaggga gttatcttaa atttcgtcaa gcgtatgcac
     4141 gaattttaaa tcaaccttta gatacgaatg cgttggctaa tgggttgttt tccgatttga
     4201 ttttgattgc tgaatctcca gatactaaat ttaaattcct agagaatact gagtattata
     4261 aaaaagaaac acagagttta tcctctgaac aagctaagaa aatttggcta actgagcaag
     4321 cgaataaagg ccttgtgatt acgccaccaa aggaaaagga aaatataagt tactacacaa
     4381 tacaagcatc ggcagattca gcgaaagagg catataccct actacagggt tacttaaagg
     4441 atgttaataa tcaagctgta acgttaagtc ttgatgagtt tgatcaaaac ataaatactc
     4501 ttttagttag tttaaagaaa gaagtcaatg atatcgactt ccagaaaaaa gcagaaaaac
     4561 tggatcaaat agcctatatt cagcgagatt taactacagc agaacaagcg ggtattactg
     4621 attatcgctc tagtaaaaat ggctttgata atgcgcaaag tagctataag ttcttgcttg
     4681 gtgaaaaact gttgtcagca gagctcaaag caactaaaga tgcccctatt atttatccat
     4741 ttagatatta tgaagtgaag cgtcaaattg atgagttaga aggaatttta cgcgataaca
     4801 ttcaggcgca agcatatcgt tatcagatgg tgccggcaga accgttaaaa aaagataagc
     4861 ctaaaaaagc actgattttg gtattaggag ctttgttagg aggaatgctg ggtattgtaa
     4921 gtgtattaat aaattccgct attactaata ggaaagaagg tcttaaataa ggttaggcag
     4981 taacattgaa ataatatttg tgggcgaatt tgctatcatt gtttttgtta ctctatggct
     5041 agtgattttg gtattaagag taaagtaata aaactattgg cttagccgat atagaaaaca
     5101 atgaggaaat taattgagat tattgcattt cgtcgatata aaatatggtg ttggatgaat
     5161 aacgctcaat tacttttcgc ctaaaataaa ttgaaggttt agtcaatgaa acttcttgtc
     5221 actggtgggg ccggttttat tggagctgct gttgttcgcc atattatcaa taatactcaa
     5281 gactctgtta ttaatcttga taaactcacc tatgccggta acttagagtc tttagctagt
     5341 gtttcggaga gtgagcgtta tgcttttgaa aaaatagata tttgcgatag ttctggatta
     5401 gagcgtgtat tttcccagca ccagcctgat gcggtgatgc acctagctgc ggaaagtcat
     5461 gttgatcgct ctattactgg cccagcggac tttattgaaa ctaatattat tggtacttat
     5521 atgctgcttg aggccgcccg tgcttactgg aatagcctaa gtgaagtgcg taaaaaggtc
     5581 tttcgctttc atcacatctc gactgatgag gtgtacggcg atttacctca tccggatgac
     5641 gttgcgtctg gactagagct tccactgttt accgaagcta ccgcatacgc gccgagtagc
     5701 ccttattctg cgtccaaagc atccagtgat catttggtac gagcttggca gcgcacgtat
     5761 ggtttgccca ctatcattac cacctgctcg aataactacg cccataccat tttcctgaaa
     5821 agttaattcc tttagtgatt tcaaatgcac tagatgggaa gccattgcct atttatggca
     5881 aaggcgatca gatccgtgat tggctttatg tagaggatca tgcgcgcgca ctctatgaag
     5941 tggtgacggc tggagtggtg ggtgaaacgt acaacattgg tggacataat gagatgcaga
     6001 atcttgatgt tgtgcatacc atctgtgatc tgctggatga gatagtacct aaggcggatt
     6061 cttaccgtaa gcagattact tatgtagcgg atcgtcctag tcacgatcgt cgttatgcca
     6121 tcgatgctag caagatcagc tgtgagctgg attggcaatc agaagaaacc tttgagtctg
     6181 gtattcgcaa gactgcgcag tggtatctgg ataaccagca gtgggtcaac aatgtgaaga
     6241 acggatccta tcagtgctgg attgatcagc tgtacgggga gaagaagtaa tgaaaggcat
     6301 tattttagcg ggtggttctg gtacccgtct ttaccccatt accatggggg gggtcaaagc
     6361 aattattgcc tgtttatgac aagcctatga tctattaccc cctatcggtg cttatgctgg
     6421 ccggtatccg agagattttg atcattacca ctcttgagga tcaagttagc tttcggcgtc
     6481 tgctgggaga tgggagtcaa tttggtattt cgcttgaata tgctattcag ctcagccctg
     6541 acggattggc acaagctttt atcattggtg cagaatttat cggcaatgac aatgtatgtt
     6601 tagctcttgt agataatata ttttggggac aaggtttttc atcaatactc aagaatgccg
     6661 ccgcaagaga aaacggggca tctatatttt gttatcaagt taaagagcct gagcgttttg
     6721 gtgtcgttga attcgaacat gacaaaaaag ctatttctat tgaagaaaaa tccataaaac
     6781 ctaaatctaa tttttcggtt aaaggtctct atttttacga taatcgagtt gtaaatatcg
     6841 ccaaaaatgt taagccatca gaacgtggtg agctagagat caccagtatt aacttggcct
     6901 atcttgaaat gggtgagtta aatgtttaac tactgggcgt ggttttgctt ggttagatac
     6961 cggtacctat gagagtttat tagaagcttc atcgtttgtt aaaacggtcg aaaaacggca
     7021 aggctataaa atcgcctgct tagaagaaat cgtgtggcgg aataattggc tgagtaacgg
     7081 gtaaatactc aaagttgcaa atcaaatgtc aaaaaatagc tatggacaat atttgtctgg
     7141 cttagtagag agtcgaaaat gattttttta aataaaccag ttgctccaaa gttagcaaag
     7201 ctaaatagct atctagagaa gatcaatgaa actggctggt atactaattt tgggcccatg
     7261 catcaggcat taactgaaag actggaagat tatctaggtg ttaaaaattt acttttagtg
     7321 agtaatggga ctcttgcgat tcaggttgct gccaaagctc taaatatctc taaatctatt
     7381 acaaccccgt ttacatttgt agctacaact tcttcgttgc tttggcaggg aatggatgtt
     7441 gcattcagtg atattaattc cggttcttta aatattgcca cggataaact tgaacaaatt
     7501 tgggggaatg aaccgtcgta tgactccttg ctcgctatcc acgtgtatgg aaatccctgc
     7561 gatgtaaaaa agattgatga actggcaaga aaatataata aaaaagtgat atatgatgca
     7621 gcgcatgctt ttggtgttaa tgttggcagt gattcagtgt taaattttgg agatgcgagt
     7681 acactgagtt ttcatgcaac taaagtgttc catactgttg aaggtggtgc aattgtcttt
     7741 aaaaataaag ttgatttaga aaaagcaaag aatttgatta atttcggcat cggcaatgat
     7801 ggggtattgg gacaacctgg tattaatgca aagttaaatg aatatcaggc tgctgttggc
     7861 ttatgcattc tagatgatat tgacgacatc cttgaccatc gagcatcact ttttgattta
     7921 tatagaaaag agttgatgaa tgttgtggat atgccacatt ggcatgatga tgcaaattat
     7981 aatggtgctt atatgccaat atgtccagag aatgaaacgg ttagattaaa tattggagat
     8041 aaattaactg aaaataatat tcagtttagg cgatattttt atccatcctt agatcaagca
     8101 tacccaaaag ttaaaagttt tggctgtcca attagcaatg ttatcgctga gaatgtgcta
     8161 tgtctgccat tgcacacata tatgacagct gcagatatat ataaagttac atctataata
     8221 aaagaggttt tttaatgaag ctagcaatta tgcagccata tttttttccc tatattggct
     8281 atttcagttt aattatgcaa tccgatgaat tcattgtttt tgatacacca cagtttatga
     8341 ggaaaggttg gattgagcgc aatagaattg gtaaattgac gggggggagt gtatatataa
     8401 aagtccctct caataaagct gaactgagta caaaaataaa agacatgtca attgataata
     8461 caattgattg gcgtggaaaa atgctcgctc aattagagat ttataagaaa agagcacctt
     8521 tttatgatga cgtgttcgcg cttgtcaaag aagttttaaa tactgaaaca tcaagcattg
     8581 tgcatctaaa taaaactgca ctagagaagg tgtgtaatta tttacgtatt gatagaaaat
     8641 tcaaagtttt ttctgaaatg aatttggaaa tagagtcacc acaggctcca gatgaatggg
     8701 cgcttaatat atgcaaagct cttgatgtga aatgttatgt taatgctgca ggaggagaaa
     8761 gtttctttga taagagcaaa tacactaaca ataacattga actatgcttt atcaatcaac
     8821 ctatagaaaa atataaacaa tttgggcatg agtttgagcc tgggctttct attattgatg
     8881 taatgatgtt caatagccca gaagaaatta tccagatgtt atctcacggc tcgcttaaat
     8941 gcagctaaaa ggactgattt aattatgctt ttaaaatctg caatagactc taataattgt
     9001 acttaccctt atttatttac agctaatgca aggacagcat ggtataaaat tcttgagtct
     9061 ataacagcta gtaaatgcaa aaggttaaaa ctacttttgc cagcgtacat tggaataaat
     9121 gacaaggagg ggtctggcgt atttgatgcg gtgttaaaaa gtcaagctga ctttgttttt
     9181 tataaggtta cggataactt acaggttgat attgaagatt ttcataaaaa aataaatggt
     9241 gaatcttttg atttagcttt aattattcac tattttggtt tttccagagt taatatgggt
     9301 gatcttaagt cagcttgcga aataaatgat gtcattttag ttgaggattg tgctcatgcg
     9361 ttttatcttg atgataaaga aagcaaaatt ggtgcttatg gagattatag tttttattct
     9421 ttgcataaat acctagctgt ttcaactgga ggcttattga aaattaataa taatatgctg
     9481 cagattccta aacttagtcc agaggatata attgacctct ctgctctaga aatgtttgcc
     9541 tcttctgatt tcaaaagaat tgcagaaatc agaagagata attataaagc atattacgat
     9601 aaattgataa ataacgataa tataaatatt ctttttgatt taaatgaaaa tgatattcct
     9661 cagacgtttc caatatttgt gaagaatggc ttgagggaaa agctctattt ctatttgcta
     9721 aataataata ttccaacagt ggctctttac tatcgaatga ttccccagat cgagccaagt
     9781 aaatttgaac tttcaatgtt gatttcatct gggattttga acttacctgt tcatcaagat
     9841 acaactttag aggatattga tttagtctgc agtaaaataa attatttttt tggtgatttg
     9901 catgactgaa gttaatcatt cattaatcta tcaactgtta ataaaggttg actcggattt
     9961 taatccgccg ttgagtctaa gtcttgattt ggatgagtat tcaaaaaaaa ttgcttcaaa
    10021 agcaatttta ttcacatgtt ttaatgataa atccatcata gcactgtgcg ctatatatgc
    10081 aacggataaa aaatactctc aggcctattt aacattgtta gctgttgacc cagcatttag
    10141 gggcgtgggc ttagcaaaga aactaatgtc tgaaatggag gcttatgttt tagatgcagg
    10201 atttaaatat gtcaaactcg aagtttataa aactaatatt agtgcactat caatgtacag
    10261 gcgtttgggt tatgagatag ttgaggagtc acctaattcc tactttttaa aaaaattaat
    10321 acttcacata gcagagtaaa tacctcaact cctataagaa ttcatgctga tgttacgtaa
    10381 aaatatttta gcaaattata taagtcaagc gtatgttgca gttattggta ttttgatttt
    10441 acctttgtat atccagtata tgggagctga agtatatggt ttaatcggtt tttttacttt
    10501 gttgcaagct tggtttggcc tgctcgattt gggcttaacg ccgaccatcg cacgtgaaac
    10561 agcccgttac catggcgggt ctatgtcggc attgcattat cggcagcttt tccgtgcact
    10621 cagtaccatt tttatcggca tagcagtcat tggtggtgtg gctttatggc tattagctaa
    10681 acccatcgct tacaaatggc ttcaggttga aacacttagc atgaatgtgg ttgtagtagc
    10741 cgttcagatc atggccgtca gcgttgcgtt gcgttggttg ggggggttgt accgaggtgt
    10801 tattaccggt tcagaacgct tggtttggtt gagtggcttc aatgccatca ttgcaacact
    10861 gcgctttccg gcggtattta tcaccatgtg gctgtatggt tttacaccaa cggtattttt
    10921 ctggcaccaa ctcgcggtgg ccattattga agtgcttgga ttgtatctga tgagtaacaa
    10981 atttaagcct gtactagcta agagtgaaat tatcggctgg agcatacaac ctgttaaacc
    11041 cgtgctgaag tttgcattgg ctatagcctt tacttcttcg gcatgggttt tggtaacaca
    11101 aaccgacaag ttgattcttt ccggcatttt accattggca gaatacggct tttttacttt
    11161 ggctgtgtta gttgccagtg ggattatgat tctgagcgct ccggtaagca cagttattat
    11221 gccccgaatg accaggcttc atgccgaagg taagcatgat gagatgattc aggtctaccg
    11281 caatgcaaca cagttagtga gcgtggttgc gggttctgct tcacttacca tcacattttt
    11341 tgccgagcca ttgctctacg catggacggg cgataaagaa atcgccagca atgccgcccc
    11401 gatcctgacg ctgtatgcac tcggtaatgg tgtacttgct gtatccgcat tcccatatta
    11461 cctgcaatat gccttaggga acttacgtta ccacctgata ggaaatctgg taattgtagt
    11521 tacccttatt ccggctatca tctgggcagc atcagagtat ggtggtgtag gtgcaggttg
    11581 ggcgtggctg ggtattaata gtttgtactt aatactttgg gttgggtatg tgcatcataa
    11641 attacagcca ggcgttcatg taggttggct gttgaaagat gttttagtaa tttacgcacc
    11701 agtcatactg gtactttttc tggcgagttc ttatatgagt tatcaaacac gacaagaagc
    11761 gttattgacg ctggttgtgc tgtcatttgt tgccattttc gttgctatag tttcatcttc
    11821 agtagcccgc aaagtgctta accaaaagtt atttggcgtt aaatcatgaa ttcagatatt
    11881 aaagtatcag tatgtgttgt tacatacaat caagaaaaat acattgctga atgcttgcaa
    11941 agtttggtgg atcagataac ggattttcct tttgagatta ttgtaggtga ggattgctct
    12001 acagataaaa ctcgtgaaat agttctagag ttccaaaata aatatccaaa catcattaag
    12061 ccattgttgc atatggaaaa tgttggtcct gttaagaatg ttattgcaac gtataagcag
    12121 gcaaaaggaa cgtatatagc gcatatggat ggcgatgatt tagctttacc aggaaaactt
    12181 caggtacagg ctgatgtatt agatgaaaat acagattgta ttatatgttc tcatgatgtt
    12241 gaattactca cattcaacgg agagtttttg aaaaggacat ttagaaagca tgagaaagtt
    12301 aaaaatacta tctttgatct ttatcaaaga cttccttttt ttgtgcactc atcaaaaatg
    12361 tttaagaatg atctcgacga aaagttttgg gagcagttgc atcctcaggc gttagatatt
    12421 gaggtgcatg ctcagcaagc caaatatggt aatatttatc atattgataa agtttttggt
    12481 gtttataggg ttggtgttgg ggtctctgta aatgcagtag cttcggttaa tccattgtta
    12541 gtggctggca acgaaagagt ttttatggat gcgttggcta cttataatgg aaaaacttct
    12601 actttgaaag cttactatgc taaaacgctt atgaattatg cctatcaatc agccatattc
    12661 ggcgataagt gtggttatgt tgcctatata cgaaaatccg tgtcaattaa gttgttttcg
    12721 gctgtgcagg ccattatgtt tatattctca tttttaccga gagtagctgt cttgatttca
    12781 aaaaaaagaa ataaaatcag attttaatag gccttgcatg actatcaatc cagttgtatc
    12841 tcttttttgt ctttacttgt tcgccaactt cattgcactt gtgcagggga tcaatgacgg
    12901 cggcttggtt cttgagggtt attttttcga attaaaaaca acgtcactcg tttattcgtt
    12961 tttattacaa accataattc tactactgtt aataggttta tatagatttt ttactactaa
    13021 aggaaattgt aaaaaaatca catatggaaa aaactggggt tggtttttaa taataattca
    13081 aatgtctttt ttgattttta atataaaaac aggcgttaat atagctggtg atggcgcacg
    13141 tatcgaaggt ggctctgtta ttaactacgt ttttgttttg ttacaacccg atatgctttt
    13201 tatgttgatt gggacttcat tgttatctgg tcggctgttt cttattaatt tgattgtttt
    13261 tttggtttcc atggcgcttc gtggttggat gggcgggttt tttataatta tttttatggt
    13321 gttatcaaga tattaccctg ttcgcatttc ctcgcggagt ttattttgta ttttattttt
    13381 ggcggtgtta tttgttttgg ttttgcccgt tattattgat atgaaatggt cgatgcgaca
    13441 gggtgtttct gttggggttt ttttttctag tatttttaat tcgttttcag ctgaaaagta
    13501 taacttggct attagctatt tactaaatcg ttttcagcat cttgggcatg tagctctgct
    13561 acttgaaaat tctgataaat tatattttga tttgtctaat ggtttgtttt caagttactg
    13621 gatggatggt ctgcctcaac atactatttc aaagattttt ggttttgagc aacataagct
    13681 taattcttat atggttgaat atttttttgg aatagaagac ccgacgtgga atactaaccc
    13741 tggcctggct ggttgggttt ttatattgca agaaaaagta gtgtttatgg ctttatattt
    13801 gttttttgtt gtcgttgctc cattctattt tattagtagg tatgctggaa gtacaatgct
    13861 tatgttgatc gcatgttttt caatagttta tctttttcat ggttggtttg gagcttattt
    13921 caatatcata ttttatggat tgattttggt tgttattagt aaattaaaag ttactaatag
    13981 atctagtgta gagtcattca ctaataaggc tgttaactaa tgtgtggcgt atctggattt
    14041 ttactatctc gtcaactttc taaggcggaa cccaaaagtc tgcaatgcat gatcgccgca
    14101 atcagctatc gtggccccga tgattcagga acgtggtatg acgaaaatca aggcattgct
    14161 ttaggccaca cccgcttagc catcgtagat ttatctcccg cagggcacca gccaatggct
    14221 tcagcctgtg accgttttgt tatcgccttc aatggtgaaa tctacaacca ccttacgtta
    14281 cgtaaacagc ttgattcaca gggcgctgcg cctgtttggc gtgggcattc agatacggaa
    14341 accttattag cttgtttcag tgcttggggt attgaagcta cgttaaaagc gacggttggt
    14401 atgtttgcgt tggctctatg ggacaagcaa gatcaacaat taactttggc ccgtgatcgt
    14461 ttgggcgaga agccactgta ttggggctgg tgtagcgata cattgctgtt tggttctgag
    14521 cttaaagccc tgaaagcaca tccagatttc aatgcaggcc tggatcgcgg tgctttgtcg
    14581 ctgttgttgc gccataacta tatccctgcg ccttatacaa tttaccaagg cattgagaaa
    14641 ttacctgctg gccagtatgt gcagatcaaa aaagggcaac tgcgtgctga cgttcagctc
    14701 aaggcgtatt ggcagttgaa tcagtcaatt gaacgcggtt tggctaatcc gttcagaggc
    14761 acggatactc aagcaacgga tttgttggag caaacgatta gccaagcggt aagcgggcag
    14821 atgctatctg atgtaccttt gggggcattt ctcagtggtg ggatagatag cagtaccgtt
    14881 gtggcactga tgcagcagca atctaaacag cctgtacgca cttttgccat tggcttcgat
    14941 gagcctggct acaacgaagc tgagtatgca aaagaagttg cgcagcattt aggtacagat
    15001 cacacagagc tttacgtcag tgctcaggat gcactggatt tagtgccgcg tttaccggat
    15061 atttattgcg agccttttgc tgatagctct cagttaccta cttttctggt tagccgtatg
    15121 gcaaagcaac atgttacggt tgcactcagt ggtgatggtg gtgatgagct atttggtggt
    15181 tataatcctt atcagtttgc acccagagtg tggagtacat tacaacggct gcctttgcca
    15241 cttcggcaaa ttgcttgtcg cttattatct ggtctgccac ttcctgataa gcttgaaaag
    15301 ctgttgcgtg tattacctgc caaagacaaa gagcagtttt atcagatatt gatgagccac
    15361 tgggataacc ccgggcagtt ggtgatcggt ggaaatgaat atccgatact gattaatagc
    15421 accgatcagt ggccgaaaac cgacagcttt gagcattgga tgatggcgat ggatgccggt
    15481 cagtacatga tcgatgatat tctggtaaaa gttgatcgtg ctgccatggc aaatagtctt
    15541 gaaactaggg tacctttgct ggatcaccga gtggtggagt tagcctggca attacccttg
    15601 cacatgaaaa tacgtggtgg tgtcggtaaa tgggtgttgc gtgaggtcct gtatcgtcat
    15661 gtacctcgtg aaatgattga gcgtcccaag aagggttttt ctgtaccttt ggggcaatgg
    15721 ctgcgtggac ctttaaggga ttgggctgag gcgctgctga ataaacagcg tttagaacaa
    15781 gagggttact tcaattctat tgttgttcgc catgtctggt ctgatcattt gcaaggcaag
    15841 tgtgatcatg cacgcaagtt atggggtatc ttgatgtttc aggcgtggtt agaaaagcag
    15901 tgatagttac acatataatt atcggcttaa atgtcggtgg tgccgagttg atgcttaaac
    15961 gtttgattga atcacatcgt gaacgaccag atattgaaca tagcatcatt tcactaaccg
    16021 atatgggcgt attgggtgag cagctcacta agcaaggtgt tgctgtttat tgcttgggca
    16081 tgtcctcaat catgaaaggc cccgtaacgt ttttcaaatt gcgcaagtta ctgagagaat
    16141 tgcgtcctga tgttgtgcat acctggatgt accatgcaga cttgctgggt gctcttgctg
    16201 cgcggagtat cggattgcgg caaatcgttt ggtgtatccg tagtacggat attaagaaag
    16261 ggggaagcaa agttaccctg attatccgta aattgtgtgc tttattttca ggttggttac
    16321 cacgagtaat cgtgtgtgca gcagatgcat ctcggaaagt acatgaagct gttggctatg
    16381 catcgaataa aatgcaggta atacccaacg ggtttgagct tgctaagttg ttgcccacag
    16441 gtagtaacga cacccacatt cgggatgagc taggcataag caaagcgtgc aggctagtgg
    16501 tatccgttgg gcgctataac ccggtaaaag accataaaac gtttattgaa gcggcaggca
    16561 aggttgcgac acagcgcaat gatgttagat ttatgttggt gggacgcgac cttgagtact
    16621 ctaactccca attgatggcc ttgatcaatg caaccgggca agcagatact ttttatcttt
    16681 tgggtgagcg caatgacgtt cctgcttgtc tgcaagcaag tgatgttttt tgcctgcact
    16741 ccgttaccga aggctttccc aatgtacttg gtgaagccat ggctgtggga ttgccctgta
    16801 tcgccacgga cgtgggtgat gctgcctatc tgttagacaa tcccgaatgg gtagtgcctg
    16861 ctgcctctcc aagtcaactc gctgataagc ttgatgtcat gctatctctt tctactacag
    16921 acagagaggt actagggcaa acgtcagcca accgtattcg tgaacatttc accatggatg
    16981 tgatcagtcg tcgctatttc gatttgtata cttcgctgat tgatgtctaa taaactttca
    17041 acccaaatta attttaacgc taggatttaa attttatgca aaacacacac atagcgatta
    17101 tcggtcttgg ctacgttggt ctgccactcg cagttgagtt tggcaagaag taccccgttc
    17161 tcggctttga tattaataaa gctcgcttgg ctgaattaag taagggccac gatagtacat
    17221 tggaagtgga tgatcatgaa ctggctgagg ccaagcatct gactttcagc agctcactcg
    17281 atgacttaaa ggcatgtaat gttttcatcg tcacagtacc aacacctatt aataaacaca
    17341 aacagcctga ccttactccg ctgattaaag ccagtgaaac cattggtaaa gtgctcaagc
    17401 aaggtgacat cgttatttat gaatccactg tttaccccgg cgcaaccgag gaagactgtg
    17461 tacctgtgct tgaacgggtc tcaggtttaa cctttaacaa agattttttc tgcggttaca
    17521 gcccagagcg tattaacccc ggcgacaaag aacatagggt tactaccatc ctgaaagtaa
    17581 cctctggttc tacaccagaa gtagcagaaa ctgtcgatca gctatatcgt tcgatcatta
    17641 ccgccggtac gcacaaagcc agttccatta aagttgctga agcagctaag gtgattgaaa
    17701 atactcagcg tgatgtgaat attggcttga tcaacgaatt agcacttatt ttcaacaggc
    17761 tgggtatcga taccgaagaa gtgctgaaag ctgctggcac taaatggaat ttcttacctt
    17821 tccgtcctgg cttggtgggg ggacattgca ttggcgtaga cccttactat cttacccata
    17881 aggctcaatc ggttggttat caccctgaaa ttattctagc aggccgtcgc ttgaatgatg
    17941 gcatgggtgc ctatgttgcc agccagctgg tgaagttgat gctgaaaaaa cgtattcaag
    18001 ttgaaggttc gcgtgttctg gtgttgggct taacctttaa agaaaactgc cccgatctgc
    18061 gtaataccaa ggtggtggat attattgacg aactgcaaga ctacggtgtt agtgttgatt
    18121 gctacgatcc ctggattaac gcaacagaag ctcagcatga atacggtatt acaccagttt
    18181 cggaacctgt tgcaggtgtt tatgacggta ttgtgttggc cgtagcccat aaagagttta
    18241 cagcaatggg tgctgaaaaa atccgtgcat tgggcaagcc agtacatgtg ttgtacgacc
    18301 ttaagtacgt actgccaact tcaactaccg atttacgtct gtaacaattt tgcgtttata
    18361 gcacttagag agcgaaataa taaaatgact gtttatagtg aattgctggc aaaattgcca
    18421 gctcagccta aagtttggct ggttacgggc gttgctggtt ttattggttc taatttatta
    18481 gagcatttgc tgaagttgaa tcagacagtg gttgggttag ataatttcgc tacaggtcat
    18541 cagcataatt tggatgaagt aaagggcctg gtgactgctg aacagtgggc tgattttacc
    18601 tttattgaag gtgatatctg taatttggat gattgccaga aggcatgtat aggggtggac
    18661 tacgttctac atcaggcggc attaggctct gtaccacgtt ccattaatga tcccatcact
    18721 accaatgcga ctaacaccag tggttttttg aacatgctag tagcagcaag ggatgcaggt
    18781 gtgaaaagct ttacctatgc agccagtagt tcgacttatg gtgaccaccc agcgttgcct
    18841 aaagttgaag aaagcatcgg taaaccactg tcaccttatg ccgtaaccaa gtacgtcaac
    18901 gagctgtatg ccgatgtgtt tgccaaaact tatggcttta aaaccattgg gttgcgctac
    18961 tttaatgtgt ttggtaaacg tcaggacccg aacggcgctt acgctgcggt tgttcccaaa
    19021 tgggtagcct ccatgctctt gggggacgat attttcatta acggcgatgg tgaaactagt
    19081 cgtgattttt gttttatcga gaatacggtt caaatgaact tacttgctgc tacagcacct
    19141 gatgaagcaa aaaatgaagt gtataacgtg gctgttggtg accgtactac gcttaatgat
    19201 ttgtttcacg cattacaagc agctttagag caaaataata agccctatgg caagacccct
    19261 gtatatcgtg attttcgagc tggagatgtg cggcactctc aggcggatat taacaaagcc
    19321 atcagtaaat tgggttataa acccgaatat agaattatgg atggaatagt taaggctata
    19381 ccttggtata tacagaatgt gggttgatat cttttgaata aaaaaatgca acatattatt
    19441 tttgtagtca atgcaccaga gttcttttta tcgcatagac tacctattgc tatcgccgcc
    19501 caaaaattgg gttatgatat tcatgttgct actgctgatg ggccggaagt tcaatctatc
    19561 cagtcccttg gttttactca tcatgttgta cctttttcta gaggcggtca aaatcctctg
    19621 aatgagttaa aaacgctaat tagtttgatt aaattattta aggcgataaa accgtcactg
    19681 gttcatctta ttactattaa accagtacta tatggtggtg tcgcggctcg actgacaggg
    19741 gttgaagccg ttgtcagtgc agtttctggt ttgggtactg tttttttggc tgaatctact
    19801 attgcgcgtt tacgtcgttg gttagtcata ttgatgtacc gtctcgcatt taatcagaag
    19861 cgtttgtctg tgatttttca aaaccccgac gatagagata ttcttctttc tttaaaagcg
    19921 ttaaaaacac atcaggtaag aatgatccga gggtctggtg ttgatctttt ggattaccct
    19981 tttctacctg aacctgaagg gactccggtt gtcgttatgg ctgcgcgttt gcttaaggat
    20041 aaaggagtat ttgagtttat tgaagctgct aaaatattga atgagcgtaa cactgcagtt
    20101 gagatgaaat taatcggtgc gcctgatcta ggtaatccta ctagtgtgtc tcaaactgaa
    20161 ttagatcaat gggccgcttt ggattttgtg caactactcg gttatcaaaa aaacatcggg
    20221 aaacattata gtgaggccaa cataatttgt ttgccttctt accgtgaggg gttgccaaaa
    20281 agtttggttg aagccgcagc ttgtggacga ccagttgtga ctactgatgt accagggtgt
    20341 agagatgcga taacacctga aaaaacaggc tttcttgtcc ctgtaaaaaa tgctactgct
    20401 ctcgcggatg caattgagat tttgattcag gatgctaatt tacgaaaatc aatgggccaa
    20461 gcgggtagag cattggctga agaggtattt gcaatcgaaa aaatcgttga acaacatatg
    20521 gctatttata gagagctttt gaaaatatga acatagaatc aaaagtttta ttaacaggtg
    20581 ctagtggttt tgttggaaat gtactcaatg cagcaatgat aaacaattat caagttttgc
    20641 ctgtagtgcg tgataagcac tcagtagatt ttgatgtttg tgttgaggta caagaaattg
    20701 ataaaaatac acaatgggtt gaagccttat ctggtgtgca ttgcattatt cattgtgccg
    20761 ctcgtgtcca cataatgaac gactcctctt cagacccttt agctgagttt cgtacggtga
    20821 acaccgaagg tacgttaaac ctagctcgtc aggctgtaga ggcgggtgta aaacgcttca
    20881 tctttttaag ttctattaag gtaaatggtg aatccacttc aaatggtgag ccgtttactg
    20941 ctttcgatct gtgtttacct gaagaccctt atggtatgtc taagtttgaa gcagagaaac
    21001 agcttattgc aatcgctaaa gattctggta tggaggtagt cattattcgc cctactttgg
    21061 tttatggtcc aggagtaaaa gccaattttg tctctctaat gaacttagtt tcaaaaggca
    21121 ttccactacc atttggttgt atcacaaaga acaagcgcag tttggtctct gtagataatt
    21181 tggtcgatct cattattact tgtattgatc accctaaagc cgcaaatcaa gttttcttag
    21241 tttctgatga ccatgatgtt tctacttctg acatggtgcg tgaactagct attgctctag
    21301 ataaacccac ttggcagctc ccattaccaa tttggtgcta caagttagtt gggaaattat
    21361 ttggtaggtc agacatcgtt gataggctaa caggaacatt acaggttgac atttctcaca
    21421 caaaagaaac tctaggttgg aagcctcctc agactctgca ggaaggcttt aaaaaaacag
    21481 cacaagcctt tcttctagca aacaataaat gatgataaaa atgattcgtt taattgatct
    21541 tttcgctgca ttctttggct tattatttct atggccagtc ttattagttg ttaccttgat
    21601 tggtcttttt gatacaggtt cgccgatttt cgttcaggag cgtgttgggc gtaacaaaaa
    21661 accatttaag ctgattaagt ttcgcactat gtcgcgggat acacaatctg ttgcgtctca
    21721 tctagcaagt actagttcaa tcactaagct tggtgttttt ttgcgtaaaa ctaagattga
    21781 tgagttgcca caattgatta atgtgctgaa aggtgaaatg agtttagttg gaccacgccc
    21841 caaccttttt aatcagcacg agttaattgc cgaacgtgat gctttgggag tatatgaggt
    21901 acttcctggt attactgggc tggctcaaat aaataatatt gatatgtcta caccaaagtt
    21961 attagccgaa acagataaga aaatgattga tacgcttacc ttgtcaaact atttcaaata
    22021 tataatgaaa accgtatcag ggagtggtgc tggagatgca ataactaagg gatgagtttt
    22081 taagtgttta gtatggctga gcatggtaat gttagttaag tctataatgg actttatcgt
    22141 aatgttaaga gaactattat gttggcacgc ttactgggat tatcaagggg acttaaacgc
    22201 agcatcatgc taaccatcga tgttgttttg ttggcttttt catattgggg cgcgttttgg
    22261 gttcgcttag atgataaaat acctctgaca gctatagaaa attggcagtt atttgcattt
    22321 cttgccgttt gtacaatttt attttttatc cgaattgggc tttatcgcgc ggtattgcga
    22381 tatgtgagtg ccaagattat tggtacagtt gcaataggca ttagtttctc gacagcgtta
    22441 ttggtgattt ccgcctattt ctctggtgtt tttttaccgc gtacagttgc agtaatatat
    22501 tttacttttt cgcttttatt tatctgcggt tctcgtttgg catttagaat gatgctgaac
    22561 tatggtgtgc gtggtcagtt acctgttatc atttatggtg ctggcgcgtc tggtcgtcaa
    22621 ttgcttccgg cgttggctca agtaagtgaa tattttccgg tagcatttgt ggatgataat
    22681 cctcgcttgc ataaggctgt cattcatggc gtaacagttt attcctcgga taaattgaat
    22741 tatctagtag atcgctatgg tataaagaaa gttcttttgg cgatgccgag tgttagtaag
    22801 tcacaaaggc agaaagtgat tgctcgttta gagcatttac cgtgtgaagt tctctctatt
    22861 ccgggtatgg tcgatttagt cgaaggtcga gcacaaatca gtaatcttaa aaaagtatcg
    22921 attgatgact tgctaggccg tgatccggtt gctcctgatg ccaaattgat ggccgagaac
    22981 attactggca aagcggttat ggtcactggg gcgggaggat cgatcggctc tgagctttgt
    23041 cgtcaaattg ttcgatataa gccggccaaa ttggttctat ttgagctgtc tgaatatgcc
    23101 ctctacgcca ttgagaaaga gctctcgacg ctgtgtgata aagagggttt ggatgttgca
    23161 gtagttcctc ttttgggctc ggtgcagcgt cagaatcgct tacagatggt gatgaagtcc
    23221 tttggtattc aaacggttta tcatgcggcc gcttataaac atgtgcctct ggttgagcac
    23281 aatgtggtgg aaggggtgcg taataatgtg tttggtacct tatactgcgc tgagtcagcg
    23341 atcgaaagtg gcgttgaaac ctttgtgttg atttccaccg ataaagcggt gcgtccgact
    23401 aacactatgg ggacaactaa gcgtctggct gagttggtat tgcaggcttt gtctgcacgg
    23461 caaagcaaaa cccgtttttg tatggtgcga tttggtaatg tgctgggctc ctcgggctca
    23521 gtcgtgccat tgtttgaaaa gcagattgcc caaggtgggc cagttaccct gactcatcgt
    23581 gacattattc gctattttat gacaattcct gaagcatcgc agttggtgat tcaagcgggg
    23641 gcgatggggc atggcggcga tgtctttgtc ttagacatgg gcgatccggt caagatttat
    23701 gacttagcca aacgcatgat ccggttaagt ggcttgactg tacgggatga taaaaatcca
    23761 gatggcgata ttgccattga agttacggga ttacgtccag gtgagaaact gtatgaagaa
    23821 ttactgattg gtgattcagt tcaaggtacc tcgcatccac gaattatgac ggccaacgaa
    23881 gcgatgttgc cgtggcagga tctatcgctc ttacttaaag agctggatca agcttgtcat
    23941 gactttgatc atgagcgaat tcgcagcttg ttgttacaag cgccggcggc attcaatcca
    24001 actgatgata tttgcgatct agtttggcag cagaaaaaat cgctgttatc acaagcgagc
    24061 aatgttattc gcctgtgatt gcttagattt aaccttccac accaattctt cacctctctt
    24121 acaaatcccc gctaggcggt gcatcgtgac cgcctttacc ctgatgcctg ctctttaaca
    24181 aacaggacat cagtgtatgt ttaaaccttt tagcgccgaa tttttcggta ctttctggct
    24241 ggttctgggt ggctgtggta gcgccttgat ctcagctgct ttcccacagt taggtattgg
    24301 ctttttgggc gtggcgttgg cgtttggttt gacggtagtc accatggctt atgcggtcgg
    24361 gcacatctcc ggagcgcatt ttaaccccgc ggtgaccttg ggtctgtggg ccggtggacg
    24421 ctttcctgca gcgcgcgtgt taccttacat catcgcgcag gttatcggcg gtattgccgc
    24481 tgcggcagtg ctgtatggta tcgctagcgg taaggcgggg tttgatgcga caaccagcgg
    24541 ctttgcggct aatggttatg gcattcactc accaggcggt tatgcgttaa gcgcctgtat
    24601 gctgagcgag tttgtcctca gtgcgttttt tgtcatcgtg atccacgggg cgacagaaaa
    24661 acgcgctcct gcgggctttg cgccattggc gattggtctg acgctgacca tcatccatct
    24721 ggtgagcatc cctgtcacca atacctcggt taacccagcg cgtagtatcg cggcggcggt
    24781 tttccaaggt acttgggcgt tagatcagtt gtggatgttt tgcttgatcc catcattagg
    24841 cggaattgcc ggtggtctga tttaccgcgc attgctggcg cgtccggctg aagcataa
//
