LOCUS       KY710728               13266 bp    DNA     linear   BCT 19-SEP-2018
DEFINITION  Proteus penneri strain G2657 O antigen gene cluster, complete
            sequence.
ACCESSION   KY710728
VERSION     KY710728.1
KEYWORDS    .
SOURCE      Proteus penneri
  ORGANISM  Proteus penneri
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Morganellaceae; Proteus.
REFERENCE   1  (bases 1 to 13266)
  AUTHORS   Yu,X., Torzewska,A., Zhang,X., Yin,Z., Drzewiecka,D., Cao,H.,
            Liu,B., Knirel,Y.A., Rozalski,A. and Wang,L.
  TITLE     Genetic diversity of the O antigens of Proteus species and the
            development of a suspension array for molecular serotyping
  JOURNAL   PLoS ONE 12 (8), e0183267 (2017)
   PUBMED   28817637
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13266)
  AUTHORS   Yu,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAR-2017) TEDA School of Biological Sciences and
            Biotechnology, Nankai University, 23 Hongda Street, TEDA, Tianjin
            300457, P.R China
COMMENT     ##Assembly-Data-START##
            Sequencing Technology :: Sanger dideoxy sequencing
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..13266
                     /organism="Proteus penneri"
                     /mol_type="genomic DNA"
                     /strain="G2657"
                     /serotype="O61"
                     /db_xref="taxon:102862"
                     /collected_by="Center for Disease Control and Prevention,
                     Atlanta, USA"
     gene            1..1251
                     /gene="cpxA"
                     /note="coding region not determined"
     misc_feature    1..13266
                     /note="O antigen gene cluster"
     CDS             1600..2817
                     /note="O-antigen flippase"
                     /codon_start=1
                     /transl_table=11
                     /gene="wzx"
                     /product="flippase"
                     /protein_id="AXY99972.1"
                     /translation="MHITIFIKNFLSMNAIYASSLIFSLITYPIVLAEIGFALWGKVA
                     LAIAITSVLTMFIEFGFNLTGIDKIANSKHIDTELYIFKSIFLVKLTCYFIILISSLI
                     IFIYSNIIDYIMLLSIILLPLSEVFQSAWYLQAKKKVHKAIWFYIIPKLLFGIIIALF
                     INKENYYNYIVYFFLSNFISNILVFGINYSYLLKNSKNNIRIKINDILILIKISYPIM
                     FSKFIGMLKDRTSFFALGHYSSNYQVGVFDLANKILQLLITPIYMAIILIFPSLKEKN
                     KNKNKKIFIGTLSSTIISGIVITFSFVFYKYTNFNISNELIKTIIITLCNIPLLYTSS
                     IIANVYFLGYREKYFSLTSSLAFIIMIISIVITYYVGEINSFTISVCFLFSNFSEALS
                     RIVIIKSKKFKNE"
     CDS             2810..3649
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /gene="gt1"
                     /product="glycosyltransferase"
                     /protein_id="AXY99973.1"
                     /translation="MNNINISVIIPVYNKDKFLIKTLSSIISQINSNDELIIINDGST
                     DNSQNIINNFYSKYNSYKNIKIFNRENQGVSFTRNEGASHAENDYLLFVDADDILLDN
                     AIERLKKLAKISRFSAATYEDNENIKSLKRISPDKFIKEFIKGNIKICVGSIIIHKEL
                     FNKYLGFNTSISHGEDQFLWLKIGEKEGLLYSNEKVITYNRNDMYSLTQNKEKPINIT
                     GQVVFFLERIHKRPFNKYIIIGLMKNIIYCTMVNINNGFYRKSYQNIIKIIHILLFKK
                     NDK"
     CDS             3639..4751
                     /note="O-antigen polymerase"
                     /codon_start=1
                     /transl_table=11
                     /gene="wzy"
                     /product="polymerase"
                     /protein_id="AXY99974.1"
                     /translation="MTNKTLLLLTLVSSILYFIKLPISPIYIIMPIVYFIFLLKMKHY
                     TFHKEDSIVVIIIIITVLYTIVYQPFLMSNIGMYLNTIISLINILVIYFTARNLDKSE
                     FEVTVYNFLKISIFILIFELTYRIINPIYIEDILLAKKDLFIYPYKRNSIMFVDSNYT
                     AILILTLISLFHLNLIKIKEYKYTYILLIILLLFTFSRSAILVYILICIIQKLNQSIS
                     FNKYKNFNRMIIFLTCISLLFFIILSFDKQNITDGSFQSKFKLLSLMFETSNKKGIIF
                     FLFGGGIGNSHNLIGMGAHNILVLLYFEYGIIFSIFLISILLFSLVKEKNNLYIFWII
                     FFVNGMSLSFFLAFVFIPLGLRLARNNGRYTCLNKS"
     misc_feature    4727..5626
                     /note="similar to gt2"
     CDS             5632..6705
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /gene="gt3"
                     /product="glycosyltransferase"
                     /protein_id="AXY99975.1"
                     /translation="MKKILLITSAFKISGPNNVVEALCHGFNKEKKRVDIIALRNKHD
                     KNYIEKIERYSHIHIKPKFIPSIIFLIYCCIKIRPDYINSHGIRADIYSLLLSIFYKK
                     KYCATIHNIPFEDYKFRYSSITAFLMLSVHKLVFKNKKITKICVSEKIMHSLNSHGAK
                     KTRFVYNGIIFDKYNKLNVHDRNKFCEQLHLDNKREKVIFCGHLTKIKNPLLILPLAK
                     ENPHIDFLVLGDGYLKKELLNNKLDNIHIYGRVKNVKDYLSISNIFFMPSITEGMPMA
                     LIEALKIGLYPLCSNIDIFRELKRNLNLDLEIFDVNDNQKLAVSFKEAMSKYKTSDNK
                     NIIMDHFSSDVMAKKYLEIFINV"
     CDS             6698..7525
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /gene="gt4"
                     /product="glycosyltransferase"
                     /protein_id="AXY99976.1"
                     /translation="MYKSIFIMSIYSLDKTDFIKRSIDSMLDQTVNNIYIYIAVDGIV
                     SSQIITLLSAYEKNHNIKIFYFNENKGLAFRLNQLIDIAIKERFDFIARMDADDICRK
                     DRIEKQINYLIRNDNISIVGSNVIEIDNNENHICEKIMDTDPFLITKNIIKKCPLNHP
                     SVMFRSSVFENGLRYNNKLKNTQDYYLWVDAIKNGFNISNINESLIYFRVDENFFSRR
                     GLKKAINDVKCRIYAMNELKKHTIKNYVFIAFLFIFRLSPKIIKKFGYKNFRNVNKL"
     CDS             7522..8697
                     /note="UDP-glucose 6-dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /gene="ugd"
                     /product="ugd"
                     /protein_id="AXY99977.1"
                     /translation="MNIKNITISGTGYVGLSNGILLSQHNKVVALDINKEKVELLNKK
                     ISPITDKEIEEFLATKELDFTATLDKEFAYKDAEFVIIATPTDYDPKTNYFNTSSVES
                     VIRDVLEYNPNTTMIIKSTIPVGFTKEMREKYNTNNIIFSPEFLREGRALYDNLYPSR
                     IVIGEQSERAQKFADLLQQGALKKDIDVLFTDSTEAEAIKLFANTYLALRVAYFNELD
                     SYAESYGLNARQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYDSVPNNII
                     SAIVEANRTRKDFIADSIITKSPKIVGVYRLIMKSGSDNFRSSSIQGIMKRIKAKGIE
                     VVIYEPEMKEETFFNSKLVRDLNEFKAMSDVIITNRMSSALNDVEEKVYTRDLFGND"
     CDS             8723..9733
                     /note="NAD-dependent epimerase/dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /gene="gla"
                     /product="gla"
                     /protein_id="AXY99978.1"
                     /translation="MKYLVTGAAGFIGFHLIEKLIQQGETVVGIDNLNDYYDISLKES
                     RLNILNQLNNFSFSLIDLADREKMASLFETEKFDKVIHLAAQAGVRYSLINPFSYADS
                     NLTGFLTILEGCRHNNVKHLVYASSSSVYGLNDELPFSPHDQANHPVSLYAATKKANE
                     LMAHSYSHLYGIPTTGLRFFTVYGPWGRPDMALFKFTKAIINDDPIDIYNNGEMKRDF
                     TYVEDIVEGIARIADVIPTPQQDWKVSTGTPANSSAPYKVYNIGNGSPVNLMDYISAL
                     ETHLGKVADKNMLPMQPGDVYTTWADTEDLFKATGYKPQTSVDEGVKQFVDWYKNYYQ
                     VK"
     CDS             9737..10240
                     /note="Methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /gene="wenM"
                     /product="wenM"
                     /protein_id="AXY99979.1"
                     /translation="MLNIVLFEPEIPPNTGNIIRLCANTGFHLHLIQPLGFTWDDKRL
                     RRAGLDYREFADIKQHHDYYAFLESEGLNPDNAQSPSGARVFALTTKGTPAHSNVSYQ
                     DGDYLLFGPETRGLPPYVLDNMPTQQKIRVPMLADSRSMNLSNTVAVVVFEAWRQLGY
                     PGALLRD"
     CDS             complement(10311..10868)
                     /note="Serine acetyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /gene="wenN"
                     /product="wenN"
                     /protein_id="AXY99980.1"
                     /translation="MALTEVTLSELKACLHAEYIGDNKPFSWIRLYHRVFFCQRSRYL
                     FWWRVAQFFYFSKNRFIKKLGIRIGAKNNRIYCNDISLRTRIGKGLSLPHPIGIVLTN
                     YCQLGENVTLMQGVTIGVKEKNGKADIRVGNNVYIGCNSSIIGGEIEIGDNAVIGAHA
                     LVLKDVGEGCRYITKVVAEIKQSSM"
     CDS             complement(10868..11701)
                     /note="Serine acetyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /gene="cysE"
                     /product="cysE"
                     /protein_id="AXY99981.1"
                     /translation="MRVSMSLEELKRVWDHIKNEARCLADCEPILASFFHATLLKHEN
                     LGSALSYMLANKLATQTMPAIAVREIVEEAYRSDNSMIESAAYDISAVRLRDPAVDKY
                     STPLLYLKGFHALQAYRIAHWLWNQDRKALAVYLQNQISVTFGVDIHPAARIGHGIML
                     DHATGIVIGETAIVENDVSILQSVTLGGTGKTCGDRHPKVREGVMIGAGAKILGNIEI
                     GRGAKIGAGSVVLHEVPAHTTVAGVPARIVGKPTSDKPSLDMDQHFNGVVPGFECGDG
                     I"
     CDS             complement(11780..12796)
                     /note="Glycerol 3-phosphate dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /gene="gpsA"
                     /product="gpsA"
                     /protein_id="AXY99982.1"
                     /translation="MNASMTVIGAGSYGTALAITLARNGHDVVLWGHDPEHVAALEQA
                     RCNQAFLPDVSFPDSLYMEASLQKAIEASRNILVVIPSHVFGDVLQQIKPFLRQDARV
                     VWATKGLEAHTGRLLQDVAREVLGNEIPLAVLSGPTFAKELAAGLPTAISVASTDNTF
                     SEELQQLFHCGKSFRVYKNPDFIGVQLGGAVKNVIAIGAGMSDGMGFGANARTALITR
                     GLAEMSRLGKALGADAATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGLDVETAQEK
                     IGQVVEGYRNTKEVRALAEQVGVEMPITEQIYQILYQHKDAKEAALSLLGRATKDEID
                     SNLF"
     gene            complement(12796..13266)
                     /gene="secB"
                     /note="glycosyltransferase"
BASE COUNT     4681 a   2193 c   2095 g   4297 t
ORIGIN
        1 atgctagaac aacatatcga agctgaatta gctcaagatc cggctaacga tctcctttgg
       61 tggcgtcgat taattcgagc tattgataaa tgggctcccc ctggccaacg tttaattatt
      121 gtcacgagtg aaggccggat tatcggtgct caacgtaatg agatgcaagt tgtcagaaac
      181 tttattggtc aatctgataa cgccgatcac cccaaaaaga aaaaatatgg tcgctctgag
      241 atgctagggc ctttttctgt aagggatggt gaagatcatt accaacttta tctcgtgcgc
      301 ccttcaagta gccctcaatc tgactttatc aacttattat ttgataaacc attgttgtta
      361 ctcatattca ccatgcttat cagcacacca ttattagtat ggctttcttg gagcttagca
      421 aaacccgcaa gacagcttaa aaatgccgct gacgatgtgg ctaaaggtaa cctacgccct
      481 caccctgaac tagaaactgg ccctcaagag tttttagccg caggcacgag ttttaatcag
      541 atgataagtg ctcttgaacg tatggtagag gcgcaacaac gtctgatctc tgatatttct
      601 catgaactac gtaccccatt aacacgctta caattagcca gtgcattgtt acgtcgtcgt
      661 agtggagaga gcaaggagct agagcgtatt gaaactgaga ctcaacgcct tgatggtatg
      721 attaatgact tactagtact ttcccgtaat cagtataaaa acgagttatt acgcgaaacg
      781 gtaaaagcca acgaattgtg ggatgacatt ttagataacg ctaaatttga ggccgaacaa
      841 agtaataaga cactgcaagt cacaacacct ccaggagcct ggcctattta ctgcaatcca
      901 tattctctgg cgagtgcatt tgagaatata gtccgtaatg ctctgcgtta ttcaaattct
      961 cgcattgaag tcgcgtttac tgaacaaaac caaggtatca ccattattgt tgatgatgat
     1021 ggccctggcg ttagccctga agatagagag catatcttcc gaccattcta tcgcactgac
     1081 gaagctagag atcgtgaatc cggtggtact ggcttaggat tagcgattgt tgaaactgcc
     1141 atcagccaac acagaggcca tgttaaagcc gatgacagtc cattaggtgg gttgagggtt
     1201 gagatttggt tgccgagagc gggtgcaagt aacaaatcgc caacggctta atagagtaat
     1261 taaactgttg tatcaaaata tcctgccatc tattgaagaa taggtggcat attctttttg
     1321 ttcgcattta ttgatgcaat tcagaatgat ctggctgaat cgatcgctat tccgatattt
     1381 atatatctac aatcaatgct aaaataccca gctattactt gaccgtctgg tttgaagagt
     1441 ctactctcag tgcggatttt cgcatattgt taaagtatgc ttatataata aaactcttat
     1501 attacatata gataggggtt tttcgagata aattttggcg ctctgggggc cgtaaactca
     1561 gtgcggtagc catgtataaa ataactaatt tcaattaaga tgcatataac aatttttatt
     1621 aaaaacttcc tttcaatgaa tgcaatttac gcatcttctt taatcttttc attaatcact
     1681 tatcccatag tactagcaga aatagggttt gcattatggg gtaaagttgc tttagcaata
     1741 gctataactt ccgtattaac aatgtttatt gaattcggtt ttaatctcac agggatagat
     1801 aaaattgcca atagtaaaca tattgataca gagctatata tttttaaatc tatattttta
     1861 gtaaaactaa cctgctactt tattatttta atttctagtt taataatttt tatatatagt
     1921 aatataatag attacataat gttactatca ataatattat taccactaag tgaagttttt
     1981 caaagtgctt ggtatttaca agcaaagaaa aaagtacata aagcaatatg gttctatatt
     2041 atcccaaaac ttctttttgg aataataatt gctttattta ttaataaaga aaattattac
     2101 aattatattg tatatttttt cctttctaat ttcatatcaa acatactagt atttggcatt
     2161 aattatagct atcttttaaa aaactcaaaa aataacattc gcataaaaat aaatgatata
     2221 cttatactaa ttaaaatatc atatcctata atgtttagta agtttatagg gatgttaaaa
     2281 gatcgaacta gtttttttgc actaggacat tactcctcca actatcaggt gggtgttttt
     2341 gatttggcta ataaaatact ccagttgtta ataactccta tatatatggc tataatacta
     2401 atttttccat ctttaaaaga aaaaaataaa aataaaaata aaaaaatttt catcggcact
     2461 ttatctagca ctataatctc aggtatagtt attacttttt catttgtttt ttataagtat
     2521 actaatttta atataagcaa tgaattaatt aaaacaataa ttattactct atgcaatata
     2581 ccattactct atacttcatc cattattgca aatgtatatt ttttagggta tagagaaaaa
     2641 tatttttctt taaccagttc tcttgcattt attataatga ttatatcaat agttattaca
     2701 tattatgtgg gcgaaataaa ctctttcaca atctccgttt gctttctatt ttctaatttt
     2761 tcagaagcac tatctagaat agtaattatt aagagtaaaa aatttaaaaa tgaataatat
     2821 aaatatatct gttattattc ctgtatataa caaagataaa tttctgataa aaactttatc
     2881 ttcaataata tctcaaataa actcaaatga tgaattaatt ataataaatg atggctctac
     2941 tgataatagt caaaatatca taaataactt ttattcaaaa tataactcat ataaaaatat
     3001 aaaaatattt aatagagaaa atcaaggtgt atcttttact cgaaatgaag gcgccagtca
     3061 cgcagaaaat gattatctac tatttgttga tgccgatgat attttattag ataatgcaat
     3121 tgaaagatta aaaaaactcg caaaaataag tagattttca gctgccacct atgaagataa
     3181 tgaaaatatc aaatcactaa aaagaatttc tcctgataaa tttattaaag agtttataaa
     3241 aggaaatatc aaaatttgtg ttggcagtat cattatacat aaagaattat ttaataaata
     3301 tttagggttc aatacatcaa tatcgcatgg tgaagaccaa tttttatggt taaagattgg
     3361 tgaaaaagaa ggactattat attctaatga aaaagtaata acatataata gaaatgatat
     3421 gtattcacta actcaaaata aagaaaagcc tattaatata acaggacaag ttgtattctt
     3481 tttagaaaga atacataaaa ggccattcaa taaatatata attattggcc ttatgaaaaa
     3541 tataatttat tgtactatgg ttaatattaa taatggtttt tacagaaaat catatcaaaa
     3601 tattattaaa ataattcaca tattattatt taaaaaaaat gacaaataaa acactactat
     3661 tattgacatt agtttcatct attttatatt ttataaaatt accaatatca cccatataca
     3721 taataatgcc aatagtatat tttatttttc ttttaaagat gaaacattac acttttcata
     3781 aagaagatag cattgtagta ataataatta ttattactgt tctatatact atagtatatc
     3841 aacctttttt aatgtccaat ataggaatgt atctaaatac catcattagt ttaattaata
     3901 tattggtaat ctattttaca gcaaggaatt tagataagtc ggaatttgaa gttacagttt
     3961 ataatttttt aaagatttcg atatttattt taatatttga gttaacatat agaattatta
     4021 atccaatata cattgaagat attctattag caaaaaaaga cttgtttatt tatccttata
     4081 aaagaaatag tataatgttt gttgatagta attatactgc aatattaatt cttactttga
     4141 ttagcttatt ccatttaaac ttaatcaaaa taaaagaata taaatatacc tatattttac
     4201 ttattatatt gcttttattt acattctcac gctcagctat tttggtatat atacttatct
     4261 gtataataca aaaattaaat caatcaattt cttttaataa atataaaaac tttaatagaa
     4321 tgataatttt tcttacatgt atttcgcttt tattttttat aattttatca ttcgacaaac
     4381 aaaatattac tgatggtagt tttcaatcta aattcaaatt attaagttta atgtttgaaa
     4441 caagtaataa aaaaggaatt atcttttttc tattcggggg ggggattgga aattcacaca
     4501 atctgatagg aatgggcgct cataatattc ttgtattgtt atattttgaa tatggtatta
     4561 ttttttccat atttctcata tcaattttat tattttcatt agttaaagaa aaaaataatc
     4621 tatatatttt ttggattata ttttttgtaa atggaatgtc acttagtttc tttttagcat
     4681 ttgtattcat tcctcttgga ttaagattag ctagaaataa tggtaggtat acgtgtctga
     4741 acaaaagtta gtttctattc tattacctat ttttaatgta gaaaattata ttatagaaac
     4801 attggttagt atagaagaac aaagttatag taatatagaa actattatta ttgatgatgg
     4861 aagctctgat aatagttatc aagtagtatt caattatata aaaaacaagc ctaatttcaa
     4921 attatataga aatatagaaa atcaagggat tagtaaaaca ttaaataaag cattagtttt
     4981 atctaatggt tattatatag ctagagtcga cggtgatgat ctattagatt gcaatagaat
     5041 ctataaacaa gtggaaaaag ttgaacactc aaatatagac atcattggat gttcacttta
     5101 tacaattgat gagtctagta gaaaaatcgg agggattaaa tacacatcaa attcaaacag
     5161 tatagaaaaa ctactcacat ttacttcacc tatatcgcat atatggctat gtaagaaaga
     5221 aatttataat aatgttggtg aatataaata tgatggtgca gaggatctat tttttataca
     5281 aagagcacat aaactagggt ataaaatatc taacctagat aattactacg gcatgtatat
     5341 tagaattaga tctggaaata caaattcatt acaaggatta aaacagcgct tccttcataa
     5401 acatgtttta aaccaagtaa aaaaaaatac agaggaacca tttatatata aagaaaaacc
     5461 ctttagagaa tttacatata aattatcttg taatttgatt aagaaaggat taagtaaaag
     5521 cctatacatt aaagtaatat attatctcat ttctattagt atatcttacg atcaatttat
     5581 atatctaatg gatagattaa aaaagaaacg attattaaat aaataaaaat tatgaaaaaa
     5641 atactattaa ttacttcagc atttaaaata tctggtccaa ataatgttgt tgaagcacta
     5701 tgtcatggat ttaataaaga aaaaaaaaga gtagatatta tcgcattaag aaataaacat
     5761 gataaaaatt atatagaaaa aatagaaagg tactctcata tacatataaa acctaaattt
     5821 ataccatcca ttatatttct tatatattgt tgtataaaaa taaggcctga ttatattaat
     5881 tctcatggca tacgtgcaga tatctattca ttattattat caatattcta taaaaaaaaa
     5941 tactgtgcga ctattcataa tattccattt gaagattata aattccgata ctcgagtata
     6001 actgcatttt taatgttatc agtgcataaa ttagttttta aaaataaaaa aataacaaaa
     6061 atatgtgtat ctgagaaaat aatgcattca ttaaatagtc acggagcaaa aaaaacacgt
     6121 ttcgtttaca atggtattat atttgataaa tataataagt taaatgtaca tgatagaaat
     6181 aaattttgtg agcagttaca tttagacaac aaaagagaaa aggttatttt ttgtggccat
     6241 ttgacaaaaa taaaaaatcc actcttaata ttaccattag caaaagaaaa tcctcatatt
     6301 gattttttag ttcttgggga tggttattta aaaaaagaac tactaaataa taaattagat
     6361 aatattcata tatatggacg cgtaaaaaat gttaaagatt atttaagtat atcaaacata
     6421 ttttttatgc cctcaataac agaaggtatg ccaatggcat taattgaagc attaaaaata
     6481 gggttatatc cattatgctc taatattgac atatttagag aattaaaaag aaatttaaat
     6541 ttagatttag agatttttga tgtaaatgat aatcaaaaac ttgcagtttc tttcaaagaa
     6601 gcgatgtcaa aatataaaac ctctgataat aaaaatatta ttatggacca tttttcttcc
     6661 gatgtaatgg ctaaaaaata tttagagatt tttataaatg tataaatcta tcttcataat
     6721 gtctatatat tcattagaca aaacagattt tatcaaacga tctattgata gcatgctaga
     6781 tcaaactgtt aataacatat atatatatat tgcagttgat ggaatagttt cctcccaaat
     6841 aataactcta ttatcagcat atgaaaagaa tcacaatata aaaatatttt actttaatga
     6901 aaataaagga ttagccttta ggttaaatca attaattgat atagcaataa aagaacgatt
     6961 tgattttata gcaaggatgg acgctgatga tatatgtaga aaagatagga tagaaaaaca
     7021 aataaattat ctaataagaa atgataatat ttctattgtt ggtagcaacg ttattgaaat
     7081 tgacaataat gaaaatcata tttgtgaaaa aataatggat accgatccat ttttgataac
     7141 taaaaatata ataaaaaaat gtccattaaa tcatccatcc gtaatgtttc gaagctcagt
     7201 gtttgaaaat ggattaagat acaataataa attaaaaaac actcaagatt attacctatg
     7261 ggtggatgct ataaaaaatg gattcaatat ttcaaatata aatgagagct taatatattt
     7321 cagagttgat gagaattttt tttcaagacg tggtttaaaa aaagccatta atgacgtaaa
     7381 atgtagaatt tacgcaatga atgaattaaa aaaacacaca ataaaaaact atgtttttat
     7441 tgcgtttctt tttatattta gactatctcc taaaatcata aaaaaatttg gatacaaaaa
     7501 tttcaggaat gtaaataagc tatgaatata aaaaatatca ccatctccgg taccggctat
     7561 gtcggtctat ctaacgggat actgctttcc caacacaaca aagttgttgc gttagatatc
     7621 aataaagaaa aagttgaatt acttaacaaa aaaatctcgc caattacaga caaagaaatt
     7681 gaagagtttt tagcaaccaa agagctcgac tttacagcaa cattagataa agaattcgct
     7741 tataaagatg ctgaattcgt tatcattgcc acaccaaccg attatgatcc taaaacgaac
     7801 tatttcaaca cctcttctgt agagtctgtt attcgtgatg ttttagaata taatccaaac
     7861 acgacaatga ttataaaatc aaccattcct gttggtttta ccaaagagat gagagagaaa
     7921 tataatacca ataatattat tttctcccct gagttcttac gtgaaggtcg tgcgctttac
     7981 gataacttat atccatctcg tattgtgatt ggtgaacaat cagaaagagc acaaaagttt
     8041 gctgaccttt tacaacaagg cgcactgaaa aaagatattg atgttctgtt cactgactcc
     8101 acagaagccg aagcgattaa attatttgct aatacttatc tagcactccg tgttgcttac
     8161 tttaatgagc tagatagcta tgccgaatct tatggcctaa atgcaagaca aatcattgaa
     8221 ggtgtctgct tagatccgcg tattggcaac cactataaca atccatcatt cggttacggc
     8281 ggttactgct taccaaaaga taccaagcaa ctgttagcca actacgactc tgtccctaat
     8341 aatattatta gtgcaattgt cgaagctaac cgcacacgta aagattttat tgcagactct
     8401 attatcacta aatcacccaa aatcgtcggc gtatatcgtt taattatgaa atctggctcg
     8461 gataatttcc gttcttcttc tatccaaggc attatgaaac gcattaaagc caaagggatt
     8521 gaagtggtga tttatgaacc agagatgaaa gaagaaacct tctttaattc aaaattagtt
     8581 cgtgatttaa atgagtttaa agcaatgtct gatgtcatta ttaccaatag aatgtcatca
     8641 gcactaaacg atgttgaaga aaaagtttat actcgtgacc tttttggtaa cgattaatta
     8701 ataaatacgg gttaattacg taatgaaata tttagtcacg ggtgcagcag ggttcattgg
     8761 ttttcatcta atagaaaaac taatccaaca aggtgaaact gttgttggta tcgataatct
     8821 caatgattat tatgatattt ccttaaaaga atccagactt aacattctga atcaattaaa
     8881 taacttttca ttttctctta ttgatctagc tgatagggaa aaaatggcta gtctatttga
     8941 aactgagaaa tttgataaag tgattcattt agctgcgcaa gcaggcgtta gatattcact
     9001 aattaacccg ttttcttatg ctgatagcaa tttaacaggc tttttaacga ttttagaagg
     9061 gtgtcgccat aataatgtca agcatcttgt ttatgcttca tcaagttctg tttatggctt
     9121 aaatgatgaa ttgccatttt cacctcacga tcaagctaat catcctgttt cattatatgc
     9181 agcaactaaa aaagctaatg aattaatggc tcacagctat tctcatttat atggtatacc
     9241 aacaactgga ttacgctttt tcactgtata tggcccttgg ggtcgccctg atatggcatt
     9301 atttaaattc acaaaagcca ttatcaacga tgatcctatc gatatttata ataatggtga
     9361 aatgaaacgc gactttactt atgttgaaga tatcgtggaa ggtattgctc gtatcgctga
     9421 cgtaatacca acaccgcaac aagattggaa agtcagtaca ggaactccag ctaatagctc
     9481 tgcaccttat aaagtctata atattggtaa tggttctcca gttaatttaa tggattatat
     9541 tagtgcatta gaaactcatt taggaaaagt tgcggataaa aatatgttac caatgcaacc
     9601 tggggatgtt tacactacgt gggcagacac tgaagattta tttaaagcaa ctggctataa
     9661 gcctcaaaca agtgtcgatg aaggtgtaaa acagttcgtt gattggtata agaactatta
     9721 tcaagttaaa taaaccatgc tcaatatcgt cttatttgaa cccgaaattc caccgaatac
     9781 gggtaatatt atccgcctgt gtgctaacac aggctttcat cttcatttga tccaaccatt
     9841 gggttttact tgggatgata aacgtctacg tcgtgcaggg cttgattatc gtgaatttgc
     9901 tgatattaaa cagcaccacg attattatgc ttttttagaa agtgaaggtt taaaccctga
     9961 taatgcacaa tcaccatcag gtgcgcgtgt atttgcctta accacaaaag gcacgccagc
    10021 acatagcaat gtcagttatc aagatggaga ttatctcctg tttggccctg aaacccgtgg
    10081 tttgccacct tatgtattag ataatatgcc aacacagcag aaaatcagag tcccaatgct
    10141 tgctgatagc cgcagtatga atctgtcaaa tacggttgcg gttgtggttt ttgaggcatg
    10201 gcgccaactt ggttatcctg gtgcattact aagagactga aatgcaaaaa gcgctgatca
    10261 taaataatga ctagcgcttt ttaacttcaa ataactaaca tgttaattta ttacattgag
    10321 gattgtttta tttcagcaac aaccttcgtg atatatcgac acccttcccc tacatccttc
    10381 agtactaatg catgagctcc aatcaccgca ttatcaccaa tctctatctc accgccgata
    10441 atcgatgagt tacaaccaat ataaacgtta ttaccaaccc gaatatccgc tttgccattc
    10501 ttttctttta caccgattgt cacaccttgc attaacgtca cattctcgcc tagctgacag
    10561 taattagtta gtacgatccc tatgggatgt ggtaatgaaa ggcctttacc tatgcgcgtt
    10621 cttagtgaga tatcgttgca atatatacga ttgtttttag caccaatacg aatgcctaat
    10681 tttttgataa aacgattttt agaaaaataa aagaattggg cgacacgcca ccaaaataga
    10741 taacgtgaac gttggcagaa aaaaacacgg tgataaagtc ttatccaact aaaaggcttg
    10801 ttatcaccta tatactcagc gtgtaaacaa gcctttagtt cagaaagggt gacttcagtt
    10861 aatgccatta aatgccatca ccacattcaa aaccgggtac gacaccatta aagtgttgat
    10921 ccatatcgag tgaaggcttg tcactggtcg gcttaccaac aatgcgagca ggaacaccag
    10981 caacggtagt gtgcgcagga acttcatgta aaacgactga tcccgcacca attttggcac
    11041 cgcgaccaat ctcgatattg ccgagtattt ttgcacccgc accaatcatt acaccttcac
    11101 gcactttagg atgacggtca ccacaagttt tacctgttcc acctaacgtc acagattgta
    11161 aaatagaaac atcgttctct acgatagcgg tttcaccaat tacaatgcct gttgcgtgat
    11221 caagcataat accgtggcca atacgggcag ctggatgaat atcaacacca aaggtcacag
    11281 aaatctggtt ttgcagatac accgctaacg ctttgcgatc ttgattccat aaccaatgcg
    11341 cgatgcgata agcttgtaag gcatggaaac cttttaaata aagcagtggt gtagagtatt
    11401 tatcaacggc aggatcgcgt aaacgcacag ccgaaatatc ataagctgcc gattcaatca
    11461 tagaattatc actacgatat gcttcttcaa caatctcccg aacagcaatc gcgggcattg
    11521 tttgagttgc tagcttattt gccaacatat aacttaaggc actacctaag ttttcatgtt
    11581 tgagtaatgt cgcatggaaa aaactcgcca aaattggctc gcaatctgcc aagcatcttg
    11641 cttcattttt aatatgatcc cagactcttt ttagctcttc tagcgacata ctcactctca
    11701 ttctttttac attgaagcct aagtaaatac ttaggcttct tatgtttaaa acagaaataa
    11761 ataactatct aaaatagact tagaacagat tgctgtctat ctcatcttta gtagctcggc
    11821 ctaataaaga taatgccgct tctttcgcgt ctttatgctg atataaaatt tggtagatct
    11881 gctcagtaat aggcatttca acaccaactt gttcggctaa tgcgcgaact tctttagtat
    11941 tacgatagcc ttcaactact tgtccaattt tttcttgggc agtctccaca tcaaggcctt
    12001 gacctaacat cataccaaag cgacgattac gagattggtt atcggtacag gttaaaacta
    12061 aatcacccaa ccccgccatg cccataaagg ttgcagcatc tgcacctaac gctttaccta
    12121 aacggctcat ttcagcaagg ccacgagtaa tcaatgctgt acgcgcatta gcaccaaacc
    12181 ccataccatc agacatacct gcgccaatag caatcacgtt ttttaccgca ccacctaatt
    12241 ggacaccgat aaagtcagga tttttatata ctcggaaact tttgccacaa tggaacaact
    12301 gttgtaactc ttcagagaag gtattgtccg ttgaagccac agaaatcgca gtaggcagac
    12361 ctgctgcaag ctctttggca aaagtagggc cagataaaac tgcaagcggg atttcattac
    12421 ctaatacttc acgcgctaca tcttgcaata agcgaccagt atgagcctca agtccttttg
    12481 tcgcccaaac aacacgtgca tcctgacgta aaaagggttt gatctgctgt aatacatcac
    12541 caaaaacatg gcttgggatc acaaccagaa tattacggct agcttcaatg gctttttgca
    12601 aagaagcttc catgtataaa ctatcaggaa aggaaacatc gggcagaaag gcctgattac
    12661 agcgagcttg ctctaacgca gcaacatgtt caggatcatg accccaaagt acaacatcat
    12721 ggccattgcg cgctaaggta atcgctaaag cggtgccgta tgaaccggca ccgataactg
    12781 tcatagaagc gttcattaag cttcttcagc cccttcatta gcggcatcag tttgttgctg
    12841 ttgtaaatag ttcataaaca acgcatcaaa gttaactggt gctaagttca gttgtgggaa
    12901 agtaccacgg ctgactaagt tagtgataca ttcacgagca taagggaaca gaacgttagg
    12961 gcaatatgca cctaagcaat gtgctaattg agtgccttca ataccttcaa cggtgaagat
    13021 acctgcttgt tgcacttcac acaggaatgc agtctcgtta tccatagttg ccgttacagt
    13081 aacgcgcaga ataacttcat agacgttttc agctaaagtg ttagaagaag tatctaaatc
    13141 taatttaact tctggttgcc actctttttg gaaaacttgt ggggcattag gcgcttcaaa
    13201 agagatatct tttgtataga tacgttgaat ttgaaaagtc atctcttggt tttgctgttc
    13261 tgacat
//
