LOCUS       MH444259               25802 bp    DNA     linear   BCT 18-AUG-2018
DEFINITION  Providencia alcalifaciens serogroup O3 antigen biosynthesis gene
            cluster, complete sequence.
ACCESSION   MH444259
VERSION     MH444259.1
KEYWORDS    .
SOURCE      Providencia alcalifaciens
  ORGANISM  Providencia alcalifaciens
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Morganellaceae; Providencia.
REFERENCE   1  (bases 1 to 25802)
  AUTHORS   Du,Y. and Liu,B.
  TITLE     Development of a Molecular Serotyping Scheme and a Multiplexed
            Luminex-Based Array for Providencia
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 25802)
  AUTHORS   Du,Y. and Liu,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2018) Teda Institute of Biological Sciences and
            Biotechnology, Nankai University, 23 Hongda street, TEDA, Tianjin,
            Tianjin 300457, China
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: Velvet Optimiser v. v2.2
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..25802
                     /organism="Providencia alcalifaciens"
                     /mol_type="genomic DNA"
                     /isolation_source="human urinary tract"
                     /host="Homo sapiens"
                     /db_xref="taxon:126385"
                     /country="Poland"
                     /note="serogroup: O3"
     misc_feature    1..25802
                     /note="antigen biosynthesis gene cluster"
     gene            28..1257
                     /gene="cpxA"
     CDS             28..1257
                     /gene="cpxA"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor protein"
                     /protein_id="AXL96301.1"
                     /translation="MLEQHIEAELAQAPMNDLLWWRRISNAIKKWAPPGQRLIIVTSE
                     GRVIGAMPSEMQVIRNFIGQSDNADHPKKKKYGRAEILGPFSIRDGEDHYQLYLVRPA
                     SSPQSDFINLLFDRPFLLLIATMLISAPLLLWLSWSLARPARKLKMAADDVAKGNLRP
                     HPELESGPQEFLSTGNSFNQMISALDGMVTAQQRLISDISHELRTPLTRLQLATALLR
                     RRHGESKELERIETETHRLDSMINDLLVLSRSQHKNEILREHIKADELWGDILDDASF
                     EAEQMNKTLDVTSHPGPWPLYCNPSAIGSAFENIVRNALRYSNTHIAVDFKEENNGIL
                     ITVDDDGPGVSPADREHIFRPFYRTDEARDRETGGTGLGLAIVETAISQHKGWVKADD
                     SPLGGLRLQIWLPEHGR"
     gene            2209..3402
                     /gene="qdtF"
     CDS             2209..3402
                     /gene="qdtF"
                     /codon_start=1
                     /transl_table=11
                     /product="N-formyltransferase"
                     /protein_id="AXL96302.1"
                     /translation="MKLIIAGKNNIAVDVTKWIIKNISDIELYSVCNENDHGNDSFQL
                     SFKKFCIQFNIPIISLEDAYHLEDAIFLSLEFDKIIHPSKFTHNRIFNIHFSYLPAYK
                     GMYTSAWPILNNEQESGVTLHKIDHGIDTGAIIDQQKFPLDIEETAKTLYLKYIKIGT
                     EIVIKNLPALISGNYSIVEQSAIKSSYYSKKSIDYKNLMIDLNKTAHEILQQIRAFTF
                     RDYQLPRIGDIDIFHGEILSSKSLSKPGTILEKNNYHLILSTIDYDIKLYSDNFDEIL
                     TACEDKSPELISKLLKTENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNINDRN
                     YKGTTVAMYFKDYMLRSGNYTGLENLINLGLDLFLKDNEGLSVFDYMRKNKNIELFNF
                     MSTFN"
     gene            3493..4374
                     /gene="rmlA"
     CDS             3493..4374
                     /gene="rmlA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate-thymidylyltransferase"
                     /protein_id="AXL96303.1"
                     /translation="MKGIILAGGSGTRLYPITMGVSKQLLPIYDKPMIYYPLSVLMLA
                     GIRETLVITTPEDLESFQRLLGDGSQFGISLQYAVQPKPEGLAQAFIIGEEFIGNDSV
                     CLVLGDNIFWGQGFSPKLLHAANTKDGATVFGYEVPDPERFGVVEFDEHYNAISIEEK
                     PLKPKSKYAVTGLYFYDNDVIDIAKNIQPSDRGELEITTVNQIYLKNKKLKVELLGRG
                     FAWLDTGTHDSLLDASSFVETIEKRQGFKIACLEEIAFRQKWLTTEQVLETANKFRKN
                     NYGQYLINLVEKRNEIN"
     gene            4361..4765
                     /gene="qdtA"
     CDS             4361..4765
                     /gene="qdtA"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-3,4-keto-hexulose isomerase"
                     /protein_id="AXL96304.1"
                     /translation="MKLINTIEFKKLGDDRGSLISLEQHKNIPFEVKRIYYIFGTKEG
                     VSRGFHAHKNLEQVAICVKGSCRFLLDDGKNKEEVILNDPSVGLYINNVTWREMHDFS
                     EDCVLIVLASELYDESDYIRNYTEFKKHTMLK"
     gene            4865..5986
                     /gene="qdtB"
     CDS             4865..5986
                     /gene="qdtB"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="AXL96305.1"
                     /translation="MIPFLDLKSVNEQYNNEIKEACSRVIDSGWYIMGKELENFEENF
                     ASYCGTKYALGVANGLDALTLVLRAWKELGKIKAGDEVIVQANTYIASVLAITENDLI
                     PVFVEPDADNYNLSISNVETAITNKTKVILPVHLYGQISPMPEIMALAKKHNLLVLED
                     CAQSHGAMIDGIKCGNWGDAAGFSFYPGKNLGALGDAGAITTNNEELANTLKALRNYG
                     SHQKYLNLFQGVNSRLDEMQAALLNVKLKYLDKDTEIRQKIALTYLEKIDNPLIKLPF
                     TANNYKQKIQSHVWHLFVIATKHRDALQAHLNHLGVQTLIHYPTPPHKQQAYKNFNHL
                     SLPITEAIHQEVLSIPIGPTMSENDIQHVIDACNSFVVE"
     gene            5986..7233
                     /gene="wzx"
     CDS             5986..7233
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AXL96306.1"
                     /translation="MNLIKTSLLSLVATFFKMLSGLVINKAISVYIGPAGLAIIGQFQ
                     NFSQVVLIAAQGAINNGVVKYTAEYGKESPKIPYLFSTALRISLVASVSVGLLLVLFS
                     SFFSSKILDSVDYNFIFIIFGFTIILFVLNGLLLSIINGLKEIRSYIKINIIQSLYSL
                     IFTSLLIYFFSLKGALIALATNQSIIFFITLVMIRKHDVIKWENFISNFDKQISKKLF
                     AFSAMAITSVIMIPTSQFIIRDYIATTEGLDQAGYWQGVWYVSAMYLMVVTTALSTYY
                     LPRLSEITDKKELKKEILQGYKILLPIIIICGLLIYLLRDVIIFILFSKDFSPMKPLF
                     TWQIIGDVFKISSWILAYIMLAKSMVKLFIVSEIIFFLSLTIISCIFVNNYGTVGATY
                     AYSLSYLFYLFFSISLMIKYTKE"
     gene            7238..8296
                     /gene="gt1"
     CDS             7238..8296
                     /gene="gt1"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AXL96307.1"
                     /translation="MKKKSVLIYGEFSGYGKSLAQGFRELGYDSEVFSFNGDGFKKIN
                     SGLNLKGSNKLLKLISIIKLLPELLKYKNILIMNPAFFNMKFLGPFILTLFKITRKNI
                     ILLCCGDDVEFIRQGKNGNIQNWPYYDINLPSKNHYSKPSDLFVNYLVATFSNKLIPA
                     MYDYHKAWSLSKYSRKLTETIPLACDGKVKTIKKKNFNDEKIIIMHGINREDFKGTKK
                     IKKALLEIEKKYKSEVEIIMPEKLPLSEYLSLMDNVDISIDQTKCNSYGMNAVYSMLA
                     GHIVLAPANQNFRNDLNIEKCPIISIDNDENHIFNAIEKIILNKNSIQKIKEDTQKYA
                     IEIHSPRIVASKIDHYLL"
     gene            8392..10278
                     /gene="asnB"
     CDS             8392..10278
                     /gene="asnB"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
                     /protein_id="AXL96308.1"
                     /translation="MCGIAGLIDFNSKSNTNTLQKMTDVLYHRGPDDSGYFFEDFKIS
                     QVGLGHRRLSILDLSTHGHQPMTYGHLTMIYNGEVYNYKEIKIELEKYGYTFESNSDT
                     EVILKAYHQWGIDAVHKFNGMFAIAIFDSNKQILTLVRDRAGVKPLYWYYKNGLFMFA
                     SELKSFHEHPDFQKELNHDGLALFLQYGYIPQPYTIFEHTHKLQAGHSLEINTQSSHI
                     NITKYWDVIDCYNRPKLNISEEEAIIETEKLLKTACEYRMVADVPVGMFLSGGYDSSA
                     VTALLQSERSEKLKTFSIGFHEEKYNEAHHAKKVAEYLGTDHTEYYCTQQDALNILPK
                     LPEIWDEPFGDASAIPTTLVSQLARKDVTVSLSADGGDEVFAGYDKYTSINNKKEIFS
                     KIPRIFHSLVKKSLNNPTVHFAARKAGIFNADDRLKRFALMLDQNEKGLLKIGSQVFT
                     DIDLQILLTLKPNRVITEFDTEITQNWLDNILAIDYKTYQLDDILTKVDRATMSVSLE
                     GREPLLDHNIINFVSRLDLKLKIRDGNKKYLLKEITHKYLPKEIMDRPKMGFGVPIFD
                     WFKDDLKQYITYYLNDSRISDGGIFSVLYIANLRDRYLAGLDVNINQIWFLLMFEMWR
                     EKWM"
     gene            10269..11189
                     /gene="orf9"
     CDS             10269..11189
                     /gene="orf9"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AXL96309.1"
                     /translation="MDVNKPYFTVFTPTYNRADRLHRVYNSLKKQTFKDFEWLIIDDG
                     STDNTKEIIEKFFSEKIVNIRYFKQENGHKKIAFNNGVKKALGYFFIPADSDDTFDYN
                     TLEIFKETYEKQDEELKTILCGGTCLCKDEQGNVIGNHYPYDDWAASVQEMRYKFRVV
                     GEKWGCVKTSILRDYPFPEIMGHVPENVVWSPIAKKYKSLFINKPLRTYFTNESDSIT
                     HTKFEKENAHGAYLLAKTTIEHELNYFFYSPIIFIKSAANYTRFKLNISKSTSKNSSL
                     RLEKNKFLGKLLITICSPIGFLLYLRDSKK"
     gene            11186..12289
                     /gene="gt2"
     CDS             11186..12289
                     /gene="gt2"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AXL96310.1"
                     /translation="MKKITFLISSLAGGGAEGVCVNIANGLADNGWSVDLVILHTHNA
                     TYLERVNPSVNLIVLNVNHARSASIPLLKYILRKKPEKILIFNYELAVLTVMLRSFFR
                     FKVKIIARNINTFSKNKTQQSSLWHRYIIKPLINYFYCKTDHIINQCQAMCDDLLTVY
                     PQLVNQTSVIYNPVAKHIEEYALNHNLANIVKQDYLLCIGRLENQKAFHYAIEAFSKL
                     KDSYPELRLKIIGKGGLEVNLQQTAINLGVIDKVDFEGFKSDIIDYYLHAKATLLTSL
                     YEGFPNVLIESITLGTPVISFDCPSGPSEIIKQGINGYLVEYKNLDSFVESCHILLKD
                     KVQIEPILATANAYSTKVAVEQYSNLLINFRVK"
     gene            12361..13311
                     /gene="wzy"
     CDS             12361..13311
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AXL96311.1"
                     /translation="MKNEIKNLSIAVLYATILVYLIPMEGILDRENYLIYANNSDLIF
                     SRYYPHNILGLITNEPIWLGINSFLNLFLLPNQVVSLIIFISSFISSYLILKNNRKYF
                     FFLLIILFFPQFIGKFIIHLRQGLAIAIFLIGWFSTSKKFRYFWFILTPFIHASFFFV
                     LFLFTYTKILNKTKLSVGIKIFSVIALGLFLGFTLEYIVSISGARQANEYTFSADNVS
                     GLSFIFWFCIFSLYFSQGRLFANKHIFPMATIAFYLSTYFLIEVTGRIFESTLILVLL
                     TSLDLSSWRKYLAISMIVSFEILNWGIRLNQPWFGWGSTF"
     gene            13284..14438
                     /gene="gt3"
     CDS             13284..14438
                     /gene="gt3"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AXL96312.1"
                     /translation="MVRLGFNFLMKKILHIITGLNDGGAEAVLFRLCSSEKKCQHVVI
                     SLTNYGKYGSLLEEIGVPVHCLNMPSSRVNINGLFGLFKLVRNIRPDAVQTWMYHADL
                     IGGVISRIAGVKNIIWGVHHTTLDKRQSKKLTILTAKTNALLSFLIPRKIIYCAMASR
                     IAQEAIGFKKNIGVIIPNGYNVNEFSPNTEMRDTFRQELQLSQDTFLIGHVGRYDPLK
                     DHKNLIQSIGLLTTGNKKIKIVMVGAMINEENDELVNYINKKSHRSLFHLLGQRSDIP
                     KIMNGLDLLVLSSSSEAFPNVLNEAMACGTPCVTTNVGDAPIIVGDTGWIVPPKDPQS
                     LVCSIAKAIDEKNNNPNNWTKRKHDCHQRIVNNFSLEKMTSSYYKVWFDE"
     gene            14525..15292
                     /gene="rmlB"
     CDS             14525..15292
                     /gene="rmlB"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="AXL96313.1"
                     /translation="MKYLVTGAAGFIGSAIVKKLNSLGHDVIGIDNINNYYDVNLKHT
                     RLNNIKNSKFKFIELDIVNKVAVSDFFMAENFDRVIHLAAQAGVRYSLQNPFAYADSN
                     LNGHLAILEGCRQAKVKHLVYASSSSVYGVTDKMPFTTDMPTDHPVSLYAATKKANEL
                     MAHSYSHLYQLPTTGLRFFTVYGPWGRPDMALFKFTKAILAGEPIDVYNNGNLSRDFT
                     FIDDIVEVYSYFRYNPTSRSAKSFRFASAKQRSLPHL"
     gene            16055..16474
                     /gene="ugd"
     CDS             16055..16474
                     /gene="ugd"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase"
                     /protein_id="AXL96314.1"
                     /translation="MGERSERAQIFADLLLEGAIKKDVPVLFTDGTEAEAIKLFANTF
                     LAMRVAYFNELDTYAKSRGLNARQIIEGVSLDPRIGSHYNNPSFGYGGYCLPKDTKQL
                     LANYDDVPNNLINAIVESNRTRKDFISMRLSPKRHVK"
     gene            17966..19096
                     /gene="gt4"
     CDS             17966..19096
                     /gene="gt4"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AXL96315.1"
                     /translation="MKIVYVITKADEIGGAQTHVRDLAKEFKNEGNEVIIIVGEEGIF
                     TKQLQEISISTIILNDLQRNISIFKDISCAIKLRKLIISLNPDIVALHSSKAGIIGRL
                     SLVATKIPVIFTAHGWAFTDGIPANKKYIYIFIEKIFSRLADKIITVSNKDKELAIKY
                     KVSSENKQIVIHNGIPDSIMQKNNAEKNNYNGFDNNKVQLISIARFSKQKDHITLFHA
                     LKKITYKNWHLKLVGKGPLLDEMIVLSNSLGLSNNITFCGEREDIEHLLVTSDIFLLS
                     TNWEGLPISIIEAMRAGLPIISTDVGGVNELISDNNNGYLVKSKDSSQLARKIESLLL
                     SKERRETFGMKSRELFINKFHISSMYIKTKNTYEAVIKEKKC"
     gene            19090..20037
                     /gene="gne"
     CDS             19090..20037
                     /gene="gne"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4-epimerase"
                     /protein_id="AXL96316.1"
                     /translation="MLTIIGGSGFIGTRLSNQLKSKNIDFKIVDIEKSEAHPEKWEFG
                     DVTKPETLIEPLKGSDVIINLSAKHKDNVHPISLYYEVNVDGAKNVCDVAEQLGIKHI
                     VFTSSVAVYGFVEKETGEDGEYHPFNHYGKSKLEAEYVYDTWQTKSADNILVTIRPTV
                     VFGENNRGNVYNLFRQIASGRFLMIGSGNNQKSMAYVENIAAFITFATTFTEGKHVFN
                     YIDKPDFTMNELTTVICGALNKPKSNIRIPYPVGILGGYCFDVLSKLTGKEFPVSSIR
                     VKKFCARTQFKSNYIGNTSFVPPVTLEQGIANTVQYEFK"
     gene            20088..21110
                     /gene="galE"
     CDS             20088..21110
                     /gene="galE"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactose 4-epimerase"
                     /protein_id="AXL96317.1"
                     /translation="MSNPSVLVTGGLGYIGSHTCVQMIQQGIQPIILDNLHNANLEVL
                     NRIETIAGTKPTFYQGDVRDKAVLDTIFAQHTISSVIHFAGLKAVGESVQKPIEYYDV
                     NVNGTLVLVQSMRQAGVKSLIFSSSATVYGDPEEVPLTENSKVGGTTNPYGTSKYMVE
                     QILTDLHIAESEWSLTLLRYFNPVGAHQSGLIGEDPQGIPNNLAPYVAQVAVGRHKEV
                     MVFGDDYPTPDGTGVRDYIHVMDLADGHISALTHTSQKSGLHIYNLGTGKGTSVLEVI
                     AAFGKAANKPIPYKIVARRPGDIAECWSSPEKALKDLQWKAQYSVQDMVNDSWRWQSK
                     NPNGYK"
     gene            21469..22611
                     /gene="wza"
     CDS             21469..22611
                     /gene="wza"
                     /codon_start=1
                     /transl_table=11
                     /product="putative polysaccharide export protein"
                     /protein_id="AXL96318.1"
                     /translation="MKYLIPIAASALIAGCQIVPGTYISTSEKTIINTGKHDINALVD
                     IYPISPQLLNEMQIAPVIAKPNPQLEKQLATYDYRVGVGDVLAITVWDHPELTIPAGS
                     YRSAADSGNWVHSDGTMYYPYIGKVSVIGKTISEIRKLVSLRLAAYIETPQVDVSIAA
                     FRSQKMYVSGEVIKAGALPITNIPLTLLEAFNTAGGLTENADWNNVVLTRNGKEIKIS
                     LQSLVQYGDLTQNYLMQPNDVLYVPRNDAQKVFVMGEVEQPATLTIDRAGMSITEALS
                     KSRGLNQTTASATGIFVIRPINKQVPNNHMPNELPPQKIAVIYQLDLSDATALVMGTK
                     FKLQPYDLVYVTAAPIVRWNRLITQLLPTITSYNLLTESTKRIYNW"
     gene            22683..22934
                     /gene="wzb"
     CDS             22683..22934
                     /gene="wzb"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine phosphatase"
                     /protein_id="AXL96319.1"
                     /translation="MQLFFPQKMIHSVGFIAPLNKPADNNAIRIAKNHNLSLEGHYSR
                     RLTEPLCQSADLILVMENHHIQKLYQQFPQTRGKVMLFG"
     gene            23073..25154
                     /gene="wzc"
     CDS             23073..25154
                     /gene="wzc"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wzc"
                     /protein_id="AXL96320.1"
                     /translation="MINKEKNQSLNADEIDLLALFKALQFNYLTISISTVIFIFIAGI
                     YCFMAAPIYQANATLQYDKVNQASLLDQMNDVMPFGNHANPVESEVEVIKSRMVLGKT
                     VSDLNLDIQISPSGLLPKLSRNTIAIDIGQYHLPSSLMDQPATLTYLNEHQYTLAIAG
                     ETYHGKIGFPIEQQGIRLLVNSFMAETGDKLTLIKNDRFSTIENLRSRISINELGKST
                     GIINLSIKGLNKQENTKILDNIIQNYIDQNIEHKKKATDNSLVFLENYLPQIKSKLDH
                     YENQLNAFRKKNESIDLSLEAKSALESALQIEEKLNELTFKEVEIQQLYTRNHPAYQS
                     LIDKRQTLLLEKERISKNIQQLPNTQQQIVRLTRDVESEQAIYNQLVAKQQELSVLNA
                     GITSNMRIIDPAESQPAPIAPKKTLIMALASILGFIVGSGYVLAKECLNNKIKNSEDI
                     EALGVQVYAAIPFSFDEKRLQSNQHRKPLAIENPCDLAIEAIRSLRTSIYFSVMNQDN
                     NIVMLTSASPNIGKSFIASNIAVVLANAGKKILLIDADLRKGHIHKTFGLENKSGLSE
                     FLSQHNPDPIIIHKQVIDNLDIISRGKSVSHSSELLMSEQFKHLLDSLKHQYDMVLLD
                     TAPIFAVTDPAIIGKYAGTSLLIAHYDVSTVKELERALKHFAQNNIEITGAILNGIHK
                     KSEDYRYVYQY"
     gene            25299..25802
                     /gene="yibK"
     CDS             25299..25802
                     /gene="yibK"
                     /codon_start=1
                     /transl_table=11
                     /product="putative tRNA/rRNA methyltransferase"
                     /protein_id="AXL96321.1"
                     /translation="MPHIVLFEPEIPPNTGNIIRLCANTGFSLHLIHPLGFTWDDKRL
                     RRAGLDYSEFADIKHHHDYYAFLESEGLNPDNNQSPTGARVFALTTKGKPSHSNVSYR
                     EDDYLMFGPETRGLPPYVLDNMPIEQKIRIPMLAESRSMNLSNSVAVVVFETWRQLGY
                     PGALLKD"
BASE COUNT     8708 a   4585 c   4562 g   7947 t
ORIGIN
        1 atggaaagtg agcaacgcca aggggatatg cttgaacagc atatcgaagc tgaactcgcc
       61 caagcaccca tgaacgacct actttggtgg cgacgaatct ctaacgccat caaaaaatgg
      121 gcgcccccag gtcaacgctt gatcattgtg actagcgaag gtcgggtaat tggtgcaatg
      181 ccgagtgaaa tgcaagtgat ccgtaatttt attggtcaat ccgataatgc ggaccacccg
      241 aagaagaaaa agtatgggcg cgcagaaatt ttgggcccat tttcgattcg agacggtgaa
      301 gatcactacc aactgtattt agttcgaccg gcgagtagtc cacaatcaga ctttattaac
      361 ctcttgtttg accgaccatt tttactcttg attgccacca tgttaatcag tgcaccactg
      421 ttattatggt tatcatggag cttggctcgc cctgcccgta aattaaaaat ggcggcagat
      481 gatgtggcaa aaggtaattt acgtccgcat cccgagctag aatctggtcc gcaggaattt
      541 ttatctacgg gcaacagttt caaccaaatg atcagtgcgt tagatggcat ggtcactgcc
      601 cagcagcgac ttatttctga tatttcgcac gagctgcgta ctccgctcac tcggctacag
      661 ctggcgactg cattattacg tcgccgccat ggtgagagta aagagctgga gcgcatcgaa
      721 acggaaactc accgtttaga cagtatgatc aacgacctac tcgttttatc tcgcagtcag
      781 cacaaaaatg aaattctccg cgaacacatc aaagctgatg agttatgggg agatattctg
      841 gatgatgcaa gcttcgaagc ggagcagatg aacaaaacac tggatgtcac gtcacaccca
      901 ggtccatggc cgttatattg taatccatcc gccattggca gtgcgtttga aaacatcgtg
      961 cgtaacgcac ttcgttattc aaacacccat attgcggttg atttcaaaga agaaaataac
     1021 ggtattctga ttactgtcga tgatgatggt cctggcgtca gcccagctga ccgtgagcac
     1081 atcttccgtc cgttctatcg tacagatgaa gcgcgagata gagaaactgg cggcacaggg
     1141 cttggcttag cgattgttga aacggcaatc tcccagcata aaggctgggt gaaagcggac
     1201 gacagcccat tgggcgggtt acgcctacag atttggctgc cagagcacgg tcgttaattt
     1261 tctctcctta ttgagattga ggtctttggt gctgatgtgc caaagacctt ttttatatat
     1321 ccgccatata ttcctatcat attccgacaa atattccttt catcgtacaa agctgtagat
     1381 aattaatctt ccagaacaaa caaaatgatt atattaattc ctcaatcgtt tgataatatt
     1441 tgcatattcg ggtttgctgc ataaactaat aagtaacaaa aatgctcaga caattcttat
     1501 aaatattata tttcaacaac ttcatcattg ttcgagtatt tatctttatc tacaccatac
     1561 gagcgtgttc ttctgaaata ttaataacat acatcaagtc acacgtgtca ttatcattat
     1621 tttttatact attcaaccgt gtacagattt ttctttgact aatgcttcaa ccgctatcca
     1681 ccattaaggt ttttatcaat atatcgacca atctcaaact ttacacttaa aatggaatga
     1741 tatgctatag aatgacgagt taactccaga taatgacgca gaaattctac gcacagtagt
     1801 gatttctagg cgcctcacat cgatagtcac cccgagactt tagtgctatt attaagggct
     1861 tttgattgat cgtgcttacg gcacgagcca actgataaga gaaggcggtc ataagcagtg
     1921 tttattaatt gagcgatttt gtaaaaaatg cagtattttc aattaataag tactaaaatt
     1981 gaaaatctaa tggcgctctg ggacccgata acccagtgcg gtagctatgg gtgttttaac
     2041 gctaaataga actgattatt atacttagct aaaaccgttt atctcttaga tatatgcaca
     2101 cattaaaacg ttaatgcaaa taaaattaat tttataagtc atagcactct tcaataatta
     2161 gacataattt agaatcataa tgattttaaa tacatggtat aaaataacat gaaacttata
     2221 attgcaggaa aaaataacat tgctgttgat gtcactaaat ggataataaa aaatatcagt
     2281 gatatagaac tgtattctgt ttgtaacgaa aatgatcacg gaaatgattc atttcaatta
     2341 tccttcaaaa aattttgtat tcaattcaat atcccgataa tatcactcga agatgcatac
     2401 catcttgaag atgctatatt cctctctctt gaatttgata aaataattca tccatcaaaa
     2461 ttcacacaca atagaatatt caatattcat ttttcatatc tacctgcata taaaggtatg
     2521 tatacttctg catggccgat tttaaataat gagcaagaat ctggagttac gctccataaa
     2581 atagatcatg gtattgatac cggagccata attgatcagc aaaaattccc actggatatt
     2641 gaagaaacag caaaaacgct atatttaaaa tatattaaaa taggaactga aatagttatt
     2701 aaaaatcttc cagctctcat tagtggaaat tattcaattg tagaacagag cgcaataaaa
     2761 tcctcctact attcaaaaaa atcaatagat tataagaact taatgataga cctaaataaa
     2821 accgctcatg agatactaca acaaattaga gcgtttacat ttagagatta tcaattacct
     2881 aggattggtg atattgatat ttttcatggt gaaattcttt catctaaatc cttatctaaa
     2941 ccagggacca ttttagaaaa aaacaattat catcttatac tatcaactat agactacgac
     3001 attaaactat atagtgataa ttttgatgaa atactcacag cctgtgagga taaaagccct
     3061 gagcttattt caaaactatt aaaaactgaa aatatattat ttgaaaaaaa tcacctaggc
     3121 tggagcccaa ttattattgc tgcataccat ggtaatatgg atgtcattga atggcttgta
     3181 agtaaaggtg taaatattaa tgaccgtaat tataaaggaa ctacagttgc aatgtatttc
     3241 aaagattaca tgttaagaag cggcaactac actggattag aaaatcttat caacctaggc
     3301 ttagatttgt ttttgaaaga taatgaagga cttagcgtat ttgattatat gagaaaaaat
     3361 aaaaatatag aactatttaa tttcatgtca acattcaact aaagatactc ttattcatta
     3421 acatcaaata tatatctact tactacccta ttcagtttta gtaaaattta tagaaaaatt
     3481 aggaagttca acgtgaaagg tattatttta gcgggtggtt caggaacaag actatatcca
     3541 atcaccatgg gtgtatcgaa acaattactc cctatttatg ataaaccaat gatttattat
     3601 ccactttcag ttttgatgtt agcgggtatt cgtgaaacgc tagttattac aactcctgaa
     3661 gatctagaaa gctttcaacg tttattaggc gatggctcac aattcggtat ctctctccaa
     3721 tacgctgtgc aacctaaacc cgaaggctta gctcaagcct tcattattgg tgaggagttt
     3781 attggcaatg atagtgtttg cttagtgctt ggcgataaca tcttctgggg tcaaggtttt
     3841 tctcctaaat tactccatgc agcaaacact aaagatggtg caaccgtatt tggctatgaa
     3901 gtgcctgatc ctgaacgttt tggtgtagtt gaatttgacg aacactacaa tgcgatttca
     3961 attgaagaaa aaccattaaa accaaaatcc aaatatgctg tcactggttt atatttttat
     4021 gataatgatg tcattgatat agctaaaaat atccaaccat cagaccgtgg tgaattagaa
     4081 attacaaccg tcaatcaaat ttatcttaaa aataaaaaac ttaaagttga attactaggt
     4141 cgtggattcg cttggttaga tacaggtacc cacgatagcc ttttagatgc atctagcttt
     4201 gttgagacga ttgaaaaacg ccaaggcttt aaaattgctt gtttagaaga aatagccttt
     4261 agacaaaaat ggttaacaac agagcaagtg ttagaaacag caaataaatt ccgtaaaaat
     4321 aattatgggc agtatttaat taacctcgtt gagaaaagaa atgaaattaa ttaacaccat
     4381 tgaattcaag aaactcgggg atgaccgagg ttcattaatt tcattagaac aacataaaaa
     4441 tattccattt gaagtaaaac gcatttatta catttttggt actaaagaag gcgtttctcg
     4501 cggatttcat gcacataaaa atttagagca agttgctatt tgtgtaaaag gaagctgtcg
     4561 tttcttgctt gatgacggaa aaaataaaga agaggtcata ttaaatgacc ctagtgtcgg
     4621 attatatata aataacgtta catggcgaga aatgcatgat ttttctgaag attgtgtctt
     4681 aattgtcctt gctagtgaac tttatgatga aagtgactat attcgaaact acactgagtt
     4741 taaaaaacac acaatgctga agtaaataac ttcttgcctt ctacactaaa ttaatatttt
     4801 tttcaaaaat agagagttga accataaatt ctcatatttt tcaaaacttc gagagtgaat
     4861 agaaatgatt ccatttttag atttgaagtc agtaaatgaa caatataaca atgaaataaa
     4921 agaagcgtgt tcaagagtta ttgattccgg ttggtatatc atgggtaaag agttagagaa
     4981 tttcgaagaa aactttgcta gctactgtgg aacaaaatat gccttaggtg ttgctaacgg
     5041 gctagatgct ttaactcttg tgctgagggc ctggaaagaa ctgggaaaaa tcaaagctgg
     5101 cgatgaagtc attgtgcaag caaataccta tattgcttct gttttagcca tcaccgaaaa
     5161 tgatcttatc cctgtatttg ttgagccaga tgcggataac tataatcttt caatcagcaa
     5221 cgtagaaact gcaatcacaa ataaaactaa agttatccta cctgttcatt tatatggtca
     5281 aatttcacca atgccagaaa ttatggcatt agctaaaaag cacaacctat tggttttaga
     5341 ggattgtgca caatctcatg gtgccatgat tgatggcatt aaatgtggta attggggtga
     5401 tgcagcgggc tttagttttt accccggtaa aaacctcgga gctttggggg atgcaggggc
     5461 aataacaaca aataatgaag aattagcaaa taccctgaag gctttgcgca attatggttc
     5521 tcatcaaaaa tatttaaacc ttttccaagg ggtaaatagc cggctagatg aaatgcaagc
     5581 tgcgttatta aatgtcaagt taaagtattt agacaaagac accgaaattc gtcagaaaat
     5641 tgcgcttact tatcttgaaa agattgataa cccattaatt aaattaccat tcactgcaaa
     5701 taactataaa cagaaaattc aaagccatgt ctggcacttg tttgttattg caacaaaaca
     5761 tagagatgcg ctacaagctc atttaaatca tttaggtgtg caaacattaa ttcattaccc
     5821 aaccccacct cataagcaac aagcttataa gaactttaac cacctatcat taccaattac
     5881 tgaagcaatt catcaagaag ttctcagtat tcccattgga cccacaatgt ctgaaaatga
     5941 tattcaacac gtcattgatg cttgtaactc atttgtggtt gagtaatgaa tttaattaaa
     6001 acctcactgt taagcttggt agcaacattc tttaaaatgc tatcaggctt agtaatcaat
     6061 aaagctattt cagtttatat tggtccggca ggacttgcca ttataggcca atttcaaaat
     6121 ttcagccaag tagttttgat tgcagctcaa ggggcaatta ataatggagt agtaaaatat
     6181 accgctgaat atggaaaaga aagccctaaa ataccctatt tatttagcac agcactaagg
     6241 ataagtttag ttgcttcagt ctctgttggt ttactacttg ttttgttttc ttcatttttt
     6301 tccagcaaaa tattagatag tgtagattat aattttatat ttataatatt tggcttcact
     6361 attatactct tcgttttaaa tggtttactt ttatccatca taaatggtct aaaagagata
     6421 cgaagttata taaaaataaa tatcatccag agtttatact ctctaatttt cacaagctta
     6481 cttatctatt ttttcagttt aaaaggtgca ttaattgcat tagcaacaaa tcaatctatt
     6541 atatttttca ttacactagt aatgataaga aagcatgatg ttattaaatg ggaaaacttt
     6601 atttctaatt ttgataaaca aatttcaaaa aaactatttg cattttctgc tatggcaatt
     6661 acatctgtca tcatgattcc tacatcacaa tttattattc gtgattatat tgcaacaact
     6721 gaagggcttg atcaagctgg ctattggcag ggggtatggt atgtatctgc aatgtaccta
     6781 atggttgtaa caactgcttt aagtacctat tatcttcctc ggctttctga aataacagac
     6841 aaaaaagaat taaaaaagga aatacttcaa ggatataaga tattattacc aattataatt
     6901 atatgtggat tgctaatata tttattacgt gacgtcatta tttttattct gttttccaag
     6961 gatttttcac caatgaagcc tctatttacc tggcaaataa ttggtgatgt atttaaaatt
     7021 tcatcttgga ttttagctta tataatgcta gcaaaatcca tggttaaact cttcattgtg
     7081 agtgaaataa tattcttttt atcattaaca attatttcat gtatatttgt taataattat
     7141 ggaacagttg gagcaactta tgcatatagc ctcagttatt tgttctattt gtttttttct
     7201 atttcactca tgattaaata tacgaaggaa taatagaatg aaaaaaaaat ccgtattaat
     7261 ctatggagaa tttagtggct atggaaaatc attagctcaa ggttttaggg aattaggcta
     7321 cgatagcgaa gtgtttagtt ttaatggcga tgggttcaag aaaataaata gcggcttaaa
     7381 cttaaaaggc agcaataaac tattaaaatt aatttccatt attaagctat taccggaatt
     7441 attaaaatat aaaaacatcc tcattatgaa ccctgctttc ttcaatatga aattcctagg
     7501 tccattcatt ctaactttat ttaaaataac aaggaaaaat attattttac tgtgttgtgg
     7561 tgatgatgtt gaattcataa gacaaggaaa gaatggtaat attcaaaact ggccttatta
     7621 tgatatcaat ctaccttcaa aaaatcatta cagtaaacca agtgatttat ttgttaatta
     7681 tctagttgca actttttcta ataaattaat acccgctatg tatgattacc ataaagcatg
     7741 gtcactatct aaatattcaa gaaaattaac tgaaacgatc cctcttgcat gtgacggtaa
     7801 agttaaaaca attaagaaaa aaaatttcaa cgatgaaaaa atcatcataa tgcatggtat
     7861 taatcgagaa gattttaaag gtacaaaaaa aataaaaaaa gcattgttag aaatagaaaa
     7921 aaaatataaa tcagaggttg aaataataat gccagaaaaa ttacctctat cagagtattt
     7981 aagcctaatg gacaatgtag atatatccat tgaccaaaca aaatgtaact catatggcat
     8041 gaatgctgtt tatagtatgc ttgcaggaca cattgtttta gcgcctgcaa accaaaattt
     8101 ccgcaatgat ttaaatatag aaaaatgtcc tataatttca attgataatg atgagaatca
     8161 tatttttaat gcaatcgaaa aaattatcct taataaaaat agcattcaaa aaataaaaga
     8221 agatactcaa aagtatgcaa tagagataca ttctcctcga attgttgcat cgaaaattga
     8281 ccattactta ttatagaatt aattttttta attaataatc ctaactttcc cttagattga
     8341 aagtttaaat taagtaatga tttaatcata tttagaaagg taaaattata aatgtgtggc
     8401 atagctggcc taatagattt caatagtaag tctaatacaa atacgcttca gaaaatgact
     8461 gatgttttat accatcgagg tcccgatgat agtggctatt tttttgaaga ttttaaaata
     8521 tctcaggttg gtttaggtca tcgccgttta tccattttag atctctctac tcacggccac
     8581 caaccaatga cttatggtca tttaacaatg atctataacg gtgaagtgta taactataaa
     8641 gagattaaaa ttgaattaga aaaatatggt tatacttttg agtctaattc cgatacagaa
     8701 gtaatcctta aagcctatca tcagtggggc attgatgctg tccataagtt taatggaatg
     8761 tttgcaattg ctatctttga tagtaacaag caaatactaa ccttggttcg tgatcgtgca
     8821 ggtgttaagc cactttattg gtattataaa aatggcttat tcatgtttgc aagtgaactt
     8881 aaaagctttc atgagcatcc tgattttcaa aaagaactaa atcatgatgg cttagcttta
     8941 tttcttcaat atggttacat tccacagccc tatactattt ttgaacacac ccataaactc
     9001 caagcaggtc attctttaga aattaatacg caaagttcac atattaatat cactaaatac
     9061 tgggatgtta tcgactgtta taaccgtcct aaactaaaca tatcagaaga agaagctata
     9121 attgaaactg aaaaattgtt aaagacagcc tgtgaatacc gtatggtagc agatgttcct
     9181 gttggaatgt ttttaagtgg aggatatgat tcatcagcag taactgcttt attgcaatct
     9241 gaacgaagcg aaaaactaaa aacattttca attggcttcc atgaagaaaa atataatgaa
     9301 gcacaccatg ctaaaaaggt agctgaatat cttggaacag atcacacaga atattactgc
     9361 actcaacaag atgctctaaa tattttacct aaactacccg agatctggga tgaaccattt
     9421 ggtgatgctt ctgcgatccc aacaacctta gtcagccaat tagcaagaaa agatgtaact
     9481 gtatcgctca gtgctgacgg aggtgacgaa gtatttgcgg gttatgataa gtacactagt
     9541 attaataaca aaaaggaaat tttctcaaaa atacctcgta tttttcattc attagttaaa
     9601 aaaagtttaa ataacccgac tgtacatttt gcagcgagaa aagccggtat ttttaacgcg
     9661 gatgaccgcc taaaacgatt tgctctaatg cttgatcaaa atgaaaaagg attactgaaa
     9721 attggttcac aagtttttac tgatatagat ttacagatat tactcaccct aaaaccaaat
     9781 cgagtgataa cagagtttga tacagaaata acgcaaaact ggctagataa tatattagcg
     9841 attgattaca aaacctatca attagatgat attttaacta aagtagatag agctacaatg
     9901 tcagtaagtc tagaaggtag ggaaccatta ttagaccata atataattaa ttttgtttct
     9961 cgactcgact taaaattaaa aatacgtgac ggtaataaaa aatacttact gaaagagatt
    10021 actcataaat acttacctaa agaaataatg gatcgaccta aaatgggatt tggtgttcct
    10081 atttttgact ggtttaaaga tgatttaaaa cagtatatta catactattt aaatgactct
    10141 aggatttcgg atggcggcat ctttagcgtc ctctatatag caaatttacg tgatcgttat
    10201 ttagctggtt tagatgtaaa cattaatcaa atttggtttt tacttatgtt tgaaatgtgg
    10261 agagaaaaat ggatgtaaat aaaccatatt ttactgtttt tacaccgaca tataaccgcg
    10321 cggatcgctt gcaccgagta tataattcat taaaaaaaca aacatttaaa gactttgaat
    10381 ggttaattat tgatgatggg tcaacagata atacaaaaga gattatcgaa aaattttttt
    10441 ctgaaaagat cgtaaatatc cgatacttca agcaagaaaa tgggcataaa aaaatagcat
    10501 ttaacaatgg cgtaaaaaaa gcgctaggct acttttttat tccagctgac tctgatgata
    10561 catttgacta taataccctt gaaattttca aagaaacata tgaaaaacag gatgaagaac
    10621 taaagactat actttgcggg gggacctgct tatgtaaaga tgaacaagga aatgtaattg
    10681 gaaatcatta tccttatgat gattgggctg cctcagttca agaaatgaga tataaattcc
    10741 gagtggtagg agaaaaatgg ggctgcgtta aaactagcat attaagagat tacccttttc
    10801 ctgaaataat gggacatgtt cctgaaaatg tagtctggtc tcctatcgca aaaaaatata
    10861 agtcattatt tataaataaa ccactaagaa catactttac taatgaatct gatagcataa
    10921 cccatactaa atttgaaaaa gaaaatgctc atggtgcata tcttctagcg aaaacaacaa
    10981 ttgaacatga gttaaattat tttttttaca gcccaataat ctttataaaa tcagctgcta
    11041 attatacacg attcaaactt aacatttcca agtcaacaag taagaacagt agccttcgat
    11101 tagaaaagaa taaatttctc ggaaagcttc tcattaccat ctgtagtcct attggttttt
    11161 tactttatct tcgagactcg aaaaaatgaa aaagataacc ttccttatta gttccctcgc
    11221 tggaggtgga gctgaaggtg tctgtgttaa tattgcaaat ggattagctg ataatggctg
    11281 gtcagttgat ctagtcattc tgcatactca taacgctaca tacttagaac gagtgaatcc
    11341 gagtgtaaat cttattgtat taaatgttaa tcatgcccgt agcgcctcta ttcctttatt
    11401 aaaatatatt ctcaggaaaa agcctgaaaa aatattaatt tttaattatg aacttgcagt
    11461 gcttacagtc atgctaagaa gcttttttag atttaaagtt aaaataattg ctagaaatat
    11521 taatactttt tctaaaaata aaactcaaca atctagttta tggcatcgat acatcattaa
    11581 accattaatt aattattttt actgtaaaac tgaccatatt atcaatcaat gccaagcaat
    11641 gtgtgatgat ttactgactg tatatccaca gttagtaaat caaacgagtg ttatttacaa
    11701 tcccgtagca aaacatatag aagaatacgc tctcaaccat aacttagcta atattgttaa
    11761 gcaggattat ttactttgca tcggaagatt agaaaaccaa aaagcatttc actatgcaat
    11821 tgaagctttt tctaagctca aagattcata tccagaatta cgcttaaaaa ttattggaaa
    11881 aggaggttta gaagtaaact tacaacaaac agctataaat cttggagtaa tagataaagt
    11941 cgattttgaa ggttttaaat cagatataat tgattactat cttcatgcaa aagcaacttt
    12001 gttgacatct ttatatgaag gatttccaaa tgttctaatt gaatctatta cattaggtac
    12061 tcctgtaatt tcatttgatt gcccaagtgg tcctagtgaa ataataaagc aaggaataaa
    12121 tggttattta gtagaatata aaaatttaga tagctttgtt gagtcatgcc atattctatt
    12181 aaaagataaa gttcaaatag aaccaatact tgcaacggct aatgcctata gtacaaaagt
    12241 agctgtggaa caatattcaa atttattaat taacttcagg gttaaataat agaatattat
    12301 caaaaattaa aaaatacaac attgaagctt cattcaaaaa gtaaatagaa aaaggctata
    12361 atgaaaaatg aaataaagaa tctcagtata gctgttttat atgctaccat attagtttat
    12421 cttattccaa tggaaggaat tttagataga gagaattatc ttatttatgc aaataattca
    12481 gatttaattt tttcaagata ttacccacat aatattcttg gtttaataac aaacgaaccc
    12541 atatggttag gtataaactc ttttctaaat ctttttttgt tgcctaatca agtagtttca
    12601 ttaattattt tcatttcttc tttcatttct tcttatttga ttttaaaaaa taatagaaaa
    12661 tatttcttct ttttattgat tatactattc ttccctcaat tcattggaaa atttataatt
    12721 catcttcgtc aaggcttggc aattgcaata tttttaatcg gatggttttc aacttcaaaa
    12781 aaatttcgtt acttttggtt tatactaaca cctttcattc atgcaagttt cttttttgtg
    12841 ttatttttat ttacgtacac taaaatatta aataaaacaa agctttcagt tggcattaag
    12901 atatttagcg tgattgcttt aggtttattt ttaggcttca ccttagaata catagtttca
    12961 atttcaggag ctcgccaagc taatgagtat acattttcag ctgataatgt cagtggctta
    13021 agctttattt tttggttctg tattttttcc ttatacttta gccaaggccg tttatttgct
    13081 aataagcata ttttccctat ggctacaata gcattctatc tttcaacgta ttttttaatt
    13141 gaagtaacag gtcgtatatt tgaaagtacg ttgatattag ttttgcttac tagtttagat
    13201 ttaagctctt ggcgaaaata tttagctata tctatgatag tttcttttga aatattaaat
    13261 tggggtatta ggttaaatca accatggttc ggctggggtt caactttttg atgaaaaaaa
    13321 tattacatat tataactggg ttaaatgatg gtggagcaga agcggtcctt tttcgtctct
    13381 gtagttccga aaaaaaatgt cagcacgttg taatttcctt aacaaactat gggaaatatg
    13441 gttctctgtt ggaagaaata ggtgttcctg ttcactgttt aaatatgcct tcaagccgag
    13501 taaatataaa tggattattt ggcctattta aattagttag aaatattcgg cctgatgcag
    13561 tacaaacttg gatgtatcat gctgatttaa ttggaggagt aatatctaga atagcgggag
    13621 taaaaaatat tatttggggt gtacatcata ctactttaga taaacgccaa tcaaaaaaat
    13681 taaccatact aaccgctaaa actaatgctt tactctcctt tcttattcct agaaaaatta
    13741 tctattgtgc gatggcatca cgtatcgcac aagaagccat tggttttaaa aaaaatatag
    13801 gtgtgataat tccaaatggc tacaatgtta atgaattttc acctaatact gaaatgcgag
    13861 atacatttag acaagaattg cagttatccc aagacacttt tctcattggt catgttggtc
    13921 gatatgaccc tcttaaggat cataaaaatc ttattcaatc tataggtcta ttaacgacgg
    13981 gtaataagaa aattaaaatt gtgatggttg gcgcaatgat taatgaagaa aatgatgaat
    14041 tagtaaatta tataaacaaa aaaagtcata gaagtttatt ccacttactt ggacaacgta
    14101 gtgatattcc aaaaataatg aatggattag atttgcttgt tctcagttca agtagtgaag
    14161 catttcccaa tgtattaaat gaagcgatgg cttgcggaac accctgtgta acaactaatg
    14221 ttggtgatgc gcctataatt gttggcgata ctggctggat tgttccacca aaagatcctc
    14281 aatcactagt ttgttctata gctaaagcta tagatgaaaa aaataacaac ccaaataatt
    14341 ggactaaaag aaaacatgat tgccaccaac gaattgtaaa taactttagt cttgaaaaaa
    14401 tgacatctag ttattacaag gtttggtttg atgaatagat ttttatttat tcttatgcat
    14461 taataatacg tttccaattc tatttatata tttaattttt taatgtttct taaggttaat
    14521 aataatgaaa tatttagtta ctggtgctgc tggttttatt ggtagtgcaa tagtaaaaaa
    14581 actgaattct ttagggcatg atgtaatagg tattgataat attaataact attatgacgt
    14641 taaccttaag catactcgtt tgaataatat taaaaattca aaatttaaat tcattgagct
    14701 tgatattgta aataaagtag ctgtttcaga tttttttatg gctgagaatt ttgaccgcgt
    14761 tatccatctt gcagcacagg caggggtgcg ttactcatta caaaacccct ttgcctatgc
    14821 agacagtaat ctgaatgggc acttggcgat tttagaaggt tgccgccaag cgaaagtgaa
    14881 gcatttagtg tatgcctctt caagttccgt gtatggcgtg acagataaaa tgccatttac
    14941 gactgacatg ccaaccgatc accctgtttc attgtatgcg gcaaccaaaa aagccaatga
    15001 gctgatggcg cattcctatt cacacttgta tcaacttccg acaacgggtt tacgcttctt
    15061 cactgtgtat ggtccatggg ggcgcccaga catggcgctg tttaaattca ccaaggctat
    15121 cttagcgggt gagcccatcg atgtttataa taatggtaat ctgagccgtg atttcacgtt
    15181 cattgatgat attgttgaag tgtattcgta tttcagatat aatcccacaa gcagatccgc
    15241 aaaatcattc agattcgcca gcgcaaagca gcgctcctta ccgcatttat aatattggta
    15301 acggacagcc tgtgaagctg atcgatttta tttcggcatt ggaaaaggca ttagggaaag
    15361 aagccattaa gaacttctta ccaatgcaag cgggtgatgt ttacacgaca tgggcagaca
    15421 ccgaagactt atttaatgtc actggttatc gcccacacgt ttctattagg cagggtgttc
    15481 aggcgtttgt tgactggtat aaatcgtatt accaccgcta ataccgatca tcaatatcat
    15541 ctacacctgt aatatccgca gaaggatttg agaggcaagt ttgaaaatag caatcgcagg
    15601 gaccggctac gtcggtctgt ctaacgccat gttactgtca caacaccacg aagtggtggc
    15661 ggtcgatatc atccctgaaa aagtggcgat gctgaacaat aagcaatccc cgattatcga
    15721 cactgaaatc gagcagtttt taacggaaaa cagctgaact tccgtgcgac cgaagataaa
    15781 gtcgaagcct atactggcgc gcaatacgtg attgttgcca cccctacgga ttacgaccca
    15841 aaaaccaact acttcaacac taattcagtc gagtccgtca ttcatgatgt gaacaaactg
    15901 aatccagacg ccacgattat cgtcaatcca ccattccagt gggctttact gcgcgtctgc
    15961 gtgaagagtt tggctacacc aacgtgattt tctccccgga gttcttgcgt gaaggtcgcg
    16021 ccctgtggga taactgtacc catcccgtat tgtggtgggt gagcgttctg aacgtgcgca
    16081 aatctttgcc gacttattgt tagaaggcgc gattaagaaa gacgtcccag tgctgttcac
    16141 tgatggcact gaagcggaag ccatcaaact gtttgcgaac actttcttag cgatgcgtgt
    16201 cgcgtacttc aatgagttag acacctacgc aaaaagccgt ggcttaaatg cgcgtcaaat
    16261 catcgaaggg gtctctttag acccgcgtat cggcagccat tacaataacc catcctttgg
    16321 ttacggtggg tactgcttac cgaaagatac gaagcagtta ctggcaaact acgacgatgt
    16381 gccaaataac ctgattaatg cgattgtgga atctaaccgc acccgtaaag actttatctc
    16441 gatgcgatta tcgccaaagc gccacgtaaa gtaggcgtat atcgcttagt gatgaaagcg
    16501 ggctctgata acttccgtgc atcggccgtt caaggcgtga tgaaacgcat taaagcgaaa
    16561 gggattgaag tggtggttta cgagccggta ctcaaaaacg aatcttccgc tcgaaagtta
    16621 tccgagattt agacgcgttc aaagccgaat gtgacattat tctagcaaac cgtatggtgc
    16681 ctgaactgga cgatgtggcg gataaagtct atacccgtga cttgtttggt aatgactaaa
    16741 tgaatattgt atatattatt acaaaagccg atgagattgg tggcgcacag atacatgtta
    16801 gagatttatc tattgcaatg acgaatctag gacataatgt aactgtcatc gttggagagt
    16861 caggtgcctt aaccactcaa ttacaagaaa ataaaataaa ataccttgtt gaaccaaaat
    16921 taactcgaaa tatagcacca attaaagatt taatctgcgc aataaaattg cgatctatat
    16981 tgaaaaaatt atctctgata ttgtttcatt gcattcatca aaagctggaa taattggtag
    17041 aacagcttta ctgggcagta aaattccatg cattttcact gcccatggtt gggcattcgc
    17101 tgatggagta tctgaaaaac gtaaaaaatt atatattttc attgaaagat ttttttctaa
    17161 tttttgcaag aaaatcatta cagtatctag gcaagataaa gagttagcga ttaaatacaa
    17221 tgtagctgat aataataaac aaattgttat ccataatggg atgcctgata aaagtataag
    17281 attccctaag atgaataata ttaatgagac tctgaaactt ataactgtcg cacgattttc
    17341 tgaacaaaaa gccatacatc cttattaatg gcgctttcta gtctatctca aaaaaattgg
    17401 acattagact taattggtaa aggccccttg aggatgaaat aaaacaatta gcgagtaagt
    17461 tagatcttag tgaaaaaatc aattttttag gtgaaaggca tgatgtgagt aagctactcg
    17521 ctaatgcaga catttttata ttaccttcaa attgggaagg cttaccaaga agtattattg
    17581 aagcaatgag cttttcatta ccaattattg cttctgatgt tggtggggta cgtagatggt
    17641 ttcatcagct aacggttatt taattccacg tggggatagc aaagcaatat catctgcagt
    17701 gaatacattg attgaaaatc aagatatccg agtaagaatg ggtaacgaaa gtagaaaaat
    17761 ttatttcaat tattttaatt ttaataaaat gctaaatgaa acacataaat tataccaaaa
    17821 aataattgag aaaagctcaa catgttaatt attatcctat tttttatcag gtatagtata
    17881 tatattttaa ggcacctact agttggtaat attcgccttt aaaatttacc ttatatttga
    17941 ttaaacaaag aaaaatggac ttgacatgaa aattgtatat gtaataacca aagctgatga
    18001 gattggtggc gctcaaaccc atgttaggga tcttgctaaa gaatttaaaa atgaaggaaa
    18061 tgaagttata attattgttg gtgaggaagg gatttttacg aaacagctac aagaaatttc
    18121 gatcagtaca atcattttaa atgacttaca acgtaatata tctatattta aagatatatc
    18181 ctgtgcaata aaattaagaa aattaattat atctttaaat cctgatattg ttgcattaca
    18241 ctcatcaaag gccggcatta taggaaggct atcattagtt gccactaaaa ttcctgtaat
    18301 ttttactgct catggttggg cattcaccga tggcattcca gctaataaaa aatatattta
    18361 tattttcata gaaaaaatat tttctcgctt agctgataaa ataatcaccg tctcaaataa
    18421 agataaagaa ctcgctatca aatataaagt ttcatccgaa aataaacaaa tcgtaataca
    18481 taatggaatt ccagattcca ttatgcaaaa aaataatgca gaaaaaaaca attacaatgg
    18541 ttttgataat aataaagtac agctaatttc tattgccaga ttttcaaaac aaaaagatca
    18601 tattacactt tttcatgcac taaaaaaaat cacctataaa aattggcatt tgaaattagt
    18661 aggtaaaggt ccccttcttg atgaaatgat agtgttatct aattccttag gcttgagcaa
    18721 caatattacc ttttgtggtg agagagaaga tatagagcat ttacttgtaa ccagcgatat
    18781 atttctttta tcaacaaact gggaagggct tcctatcagt atcattgaag ctatgagagc
    18841 cggattaccc attatttcta ctgatgttgg cggtgttaat gagcttattt ctgataacaa
    18901 taatggatat ttagttaaat ctaaagatag ctctcaacta gcaagaaaaa tcgaatcttt
    18961 gctcttatct aaagagcgta gagaaacatt tggtatgaaa agtagggaac tattcattaa
    19021 caaatttcat attagcagta tgtatatcaa aactaaaaac acatatgaag cagtaattaa
    19081 ggaaaaaaaa tgctaacaat catcggtggc tccggcttca tcggaacacg tctgtcaaac
    19141 caattaaaat ctaaaaatat cgatttcaaa attgttgata tcgagaaaag tgaagcacat
    19201 cccgaaaagt gggaatttgg cgatgtcacc aagcctgaaa cgcttatcga gccactgaaa
    19261 ggtagtgatg tcattattaa cctatcagca aaacataaag ataatgttca tcctattagc
    19321 ctttactatg aagtgaacgt tgatggtgcc aaaaacgtct gtgatgtcgc tgaacaactg
    19381 ggtattaagc acattgtttt cacttcctca gttgctgttt atggcttcgt tgaaaaagaa
    19441 accggagaag atggcgaata tcatccattt aaccactatg gtaaatctaa gttagaagct
    19501 gaatatgttt acgatacatg gcaaacaaaa tcagcggaca atatcttagt tactattcgc
    19561 ccgaccgttg tctttggtga aaataaccgt ggtaacgttt ataacctatt ccgccaaatt
    19621 gcgtctggtc gattcttaat gatcggttcg ggtaataacc aaaaatcaat ggcatatgta
    19681 gagaatattg cagcgtttat tacattcgca accaccttca ctgaaggaaa gcatgtattc
    19741 aattacatcg ataagcctga ttttacaatg aacgagttaa caacggtcat ttgtggcgcc
    19801 ctcaataagc caaaatccaa tatccgcatt ccatatccag ttgggatttt aggtggctac
    19861 tgttttgacg tactttctaa actaactggt aaagaatttc cagtgagtag cattcgtgtg
    19921 aaaaaattct gtgctcgtac acaatttaaa tctaattaca ttggcaatac ctcttttgtt
    19981 ccacccgtta ctttggagca aggcatcgcc aatactgtgc agtatgagtt taaataaatc
    20041 taatttctct taatcgcaat tttgagattt atagacagga tttcaccatg agtaacccta
    20101 gcgtattagt cacaggcggt cttggctata ttggtagcca tacctgcgta caaatgatcc
    20161 agcaaggtat tcagccgatc attttagata acctccacaa tgctaacctt gaagtactta
    20221 atcgcattga aactatcgcg ggaactaaac cgacgtttta tcaaggtgat gtgcgtgata
    20281 aagccgtact tgataccatt tttgcacagc atacgattag ttctgtaatc cactttgctg
    20341 gtttaaaagc ggtaggggaa tctgttcaaa aaccgattga atattatgat gtgaatgtga
    20401 atggcacttt ggttttagtc caaagcatgc gtcaggcggg tgttaaaagc ttaattttca
    20461 gctcatctgc aacggtatat ggtgacccag aagaagttcc tctgacggag aattcaaaag
    20521 ttggtggtac caccaaccca tatggcacca gtaagtatat ggtagaacaa atactgactg
    20581 acctacatat cgcagaaagc gaatggtctt tgaccttatt acgttacttc aaccctgttg
    20641 gcgctcacca atcaggctta attggtgaag atccacaagg tatcccgaat aaccttgctc
    20701 catatgttgc ccaagttgca gtaggtcgcc ataaagaagt tatggtattt ggtgatgatt
    20761 accccactcc tgatggaaca ggggtgcgcg actatatcca cgtcatggat ttagccgatg
    20821 gtcacatttc agcactaacc cataccagcc aaaaatcggg gttacatatt tataatcttg
    20881 gtacaggcaa aggtactagc gtattggaag tgatcgctgc atttggtaaa gctgccaata
    20941 agccgattcc atataaaatt gttgctagaa gacctggcga tattgctgaa tgttggtcta
    21001 gccctgaaaa agcacttaaa gacctacaat ggaaagcaca atattctgta caagatatgg
    21061 tgaatgatag ttggcgctgg caatcaaaaa atcctaacgg ctataaataa ccgttttgat
    21121 cattactaag gcgagcactc agctcgcctt ttttatattt aaaaatcccc cttctatacc
    21181 ccccattcga actctcttcc ttaactctct tttactctaa aaataacgct ctaatattta
    21241 aataaagtct taaaaataat tccattctcg tcattacaca aaaaacatcc aaaaaatcaa
    21301 taaccttttt tattctatta tatttttata taagtaggtt tttcagacaa aatgtttgaa
    21361 tatcaattaa gaattaaatt attatgccag ctagaattat atgtttgtgt aacttcaatg
    21421 tctgaaatgc acgctttcct atcctgattt agggcgatta ccatgttgat gaaatacctt
    21481 attcctatag cagccagcgc gctcattgct gggtgccaaa tcgtccctgg aacgtatatt
    21541 tccacatcag aaaaaaccat tattaacact ggtaaacatg acattaatgc gcttgtggat
    21601 atctacccta tctccccaca gttgctaaat gaaatgcaga ttgcccctgt gatcgccaaa
    21661 ccaaatccac aactggaaaa acaattagcc acttatgact atcgggttgg cgttggcgat
    21721 gtattggcca ttacggtttg ggatcacccc gagctcacca ttcctgcggg ttcttatcgc
    21781 agcgcagctg attccggaaa ttgggttcac tccgatggca caatgtatta tccctatatt
    21841 ggaaaagtat ccgttatcgg aaaaacaatt agtgaaatac gaaaattagt gagcctccga
    21901 ctcgccgcct atattgaaac accgcaagtt gatgtcagta ttgcggcatt tcgctcacaa
    21961 aaaatgtatg tttctggtga ggtcatcaag gcgggagcgc ttcccatcac aaatataccg
    22021 ctaaccctct tagaggcatt caatacggca ggtgggctca ctgaaaacgc agattggaat
    22081 aacgtggtgc ttacccgtaa cggcaaagaa atcaagatct cactacaatc cttagttcag
    22141 tatggcgacc taactcagaa ctacttaatg cagcccaatg atgtgctata tgtgccccgc
    22201 aatgatgcac aaaaagtatt tgtgatggga gaagtcgaac aaccagcgac cctgacgatc
    22261 gaccgtgcag gcatgagtat taccgaggcg ctcagtaaat ccagaggact caatcaaaca
    22321 acagcaagtg cgaccggtat atttgtgatt cgccctatta ataagcaagt accgaataat
    22381 catatgccaa atgagctacc gcctcaaaaa atagcggtta tttatcagct agatctatcc
    22441 gatgcgaccg cattagtgat gggaaccaaa tttaaattac agccttatga ccttgtttat
    22501 gtgaccgcag cgcctatcgt tcgctggaac cgtttaatta cccaactctt gccaaccatc
    22561 acgtcataca acctgttaac cgaaagtact aagcgtattt ataactggta atacctatgt
    22621 tcaataatat ccttattata tgcatgggca atatctgccg ttcccccact ggagaacgct
    22681 taatgcagtt atttttccct caaaaaatga ttcattccgt cggctttatc gcgccactga
    22741 acaaacctgc ggataacaat gctatccgta ttgctaaaaa ccataatctc tctttagagg
    22801 ggcattattc tcgccgttta actgaacccc tatgccaatc agcagactta atccttgtga
    22861 tggaaaacca ccatatccaa aaactctatc aacagtttcc gcaaactcgc ggcaaagtca
    22921 tgttattcgg ttaatggcta aacaaatctg aaatccccga tccctataaa catagtgatg
    22981 agatgtttga acatgtttat caacttatgg aacaagcggc cagttcctgg caagggaaaa
    23041 tttaattttt aactgatggc aaaactaaca taatgataaa taaagaaaaa aaccaatcgc
    23101 taaatgcaga tgaaatcgac cttctcgcct tatttaaagc attacaattc aattatttaa
    23161 caataagtat ttcgactgtt atttttatat tcattgcagg aatatattgt tttatggctg
    23221 cccccatcta tcaagctaat gccacgctgc aatatgacaa ggtcaaccaa gcatcattat
    23281 tagatcaaat gaatgacgtg atgcccttcg gcaatcatgc aaatccggta gaatcagaag
    23341 ttgaagtgat aaaatcccgc atggttttag gtaaaacagt ctcagatctt aatttagata
    23401 ttcaaatatc gccatcaggg ctgttgccta aactgagcag aaatacaatc gccatcgata
    23461 ttgggcaata tcatttaccc tctagcttaa tggatcagcc agcaacacta acgtatctca
    23521 atgaacatca atatactttg gctattgcag gggaaactta tcacggcaaa attggcttcc
    23581 ccatagagca acagggtatt cgcctattag tgaattcatt catggcagaa acgggagata
    23641 aactgaccct gataaaaaat gatcggtttt caactatcga aaatttgcgt agtcgtatca
    23701 gcattaatga gcttggaaaa agtactggaa tcattaattt atcgattaag ggactcaata
    23761 agcaagaaaa taccaaaata ctggataaca ttattcaaaa ttatatcgat caaaatatag
    23821 agcataagaa aaaagccact gataactcgt tggtcttttt agagaattat ttgccccaaa
    23881 taaaaagtaa gcttgaccat tatgaaaatc aattaaatgc ttttcgtaaa aaaaatgagt
    23941 ctattgacct ctctttagaa gcgaaatccg cacttgaaag cgcattacaa atagaagaaa
    24001 aactcaacga gctgacgttc aaagaagtgg aaattcaaca gttatatacc cgtaatcacc
    24061 ctgcttacca atccttgata gataaacgcc aaacattact actcgaaaaa gaacgtatca
    24121 gtaaaaatat ccaacagctg ccaaatactc agcaacagat tgttcggcta actcgagatg
    24181 ttgaatcaga acaggcaatt tataatcaat tggttgcgaa gcaacaagaa ctcagtgtac
    24241 tcaatgctgg gataacctct aacatgcgca tcattgaccc ggcagaatcg cagcccgcgc
    24301 ctattgcgcc gaaaaaaacc ttaattatgg ctttagcatc cattctaggt ttcattgtcg
    24361 gtagcggtta tgtgctcgcc aaggaatgcc tgaataataa aattaaaaat tctgaagata
    24421 tcgaagcgct cggtgttcag gtttatgcag ccattccatt ttcttttgat gaaaaaagat
    24481 tacagtctaa tcaacatcga aagccattag cgattgaaaa tccatgcgat cttgcaatag
    24541 aagccatccg ttcattaaga acgagcatct atttttcagt catgaaccaa gacaataaca
    24601 ttgtcatgct gactagcgcg tcgcccaaca ttggcaaaag cttcattgct tcaaatatcg
    24661 ctgttgtcct cgcaaatgca ggtaaaaaaa ttctgcttat tgatgccgac ttacgtaagg
    24721 gccatatcca taaaactttt ggcttagaaa ataaatcggg gctttcagag ttcttatctc
    24781 aacacaatcc tgacccaatc attattcata aacaagttat tgataatttg gatattataa
    24841 gccgaggaaa gagtgtttct cactcttccg agctgctcat gagcgaacaa tttaaacatt
    24901 tattggactc gcttaagcat caatatgaca tggtactgct tgataccgcg cctatttttg
    24961 cagtaaccga tcctgcaatt attggtaaat atgcgggaac ctcgctccta attgcacatt
    25021 atgatgtcag taccgtgaaa gagctcgaac gtgctcttaa acattttgct caaaataata
    25081 ttgaaattac aggtgcgatc ctcaatggta ttcacaagaa atcagaggat tatcgctatg
    25141 tttaccagta ttaatgggat ggcgagcgat tagctcgcct ttttataccc tcaaattatt
    25201 ctgtttcagc ctcgtgccat gcaatagatg catctttcca aatttgcgcg taaactctgc
    25261 atcatctttt ttcatctaga ccaatagcca ttaacgttat gccacatatt gttttattcg
    25321 aacctgaaat cccacccaat acgggcaaca tcatccgctt atgtgctaat acaggtttta
    25381 gcttacacct tattcacccg ctgggtttta cttgggatga caaacgcttg cgccgcgcag
    25441 gactcgatta cagtgagttt gcggacatca aacatcacca tgattattat gcattcttag
    25501 aaagtgaagg gttaaatcct gataataatc agtcgccaac aggcgctcgt gtgtttgcgt
    25561 tgacaaccaa aggtaaaccg agccacagca atgtgagcta tcgggaagat gattatttga
    25621 tgtttggacc agaaactcgt ggcttgccgc cttatgttct cgacaatatg ccaatcgagc
    25681 agaaaattcg tatcccgatg ctagctgaaa gccgcagtat gaacctgtct aactcggtcg
    25741 ccgttgtggt tttcgaaact tggcgccagc ttgggtaccc gggtgcgctg ctgaaagact
    25801 ag
//
