LOCUS       MH444265               21933 bp    DNA     linear   BCT 18-AUG-2018
DEFINITION  Providencia alcalifaciens serogroup O31 antigen biosynthesis gene
            cluster, complete sequence.
ACCESSION   MH444265
VERSION     MH444265.1
KEYWORDS    .
SOURCE      Providencia alcalifaciens
  ORGANISM  Providencia alcalifaciens
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Morganellaceae; Providencia.
REFERENCE   1  (bases 1 to 21933)
  AUTHORS   Du,Y. and Liu,B.
  TITLE     Development of a Molecular Serotyping Scheme and a Multiplexed
            Luminex-Based Array for Providencia
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 21933)
  AUTHORS   Du,Y. and Liu,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2018) Teda Institute of Biological Sciences and
            Biotechnology, Nankai University, 23 Hongda street, TEDA, Tianjin,
            Tianjin 300457, China
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: Velvet Optimiser v. v2.2
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..21933
                     /organism="Providencia alcalifaciens"
                     /mol_type="genomic DNA"
                     /isolation_source="human urinary tract"
                     /host="Homo sapiens"
                     /db_xref="taxon:126385"
                     /country="Poland"
                     /note="serogroup: O31"
     gene            1..1371
                     /gene="cpxA"
     CDS             1..1371
                     /gene="cpxA"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor protein"
                     /protein_id="AXL96407.1"
                     /translation="MINSLTARIFAIFWFTLALVLMLVLMVPKLDSRQLTVLMESEQR
                     QGDMLEQHIEAELAQAPMNDLLWWRRISNAIKKWAPPGQRLIIVTSEGRVIGAMPSEM
                     QVIRNFIGQSDNADHPKKKKYGRAEILGPFSIRDGEDHYQLYLVRPASSPQSDFINLL
                     FDRPFLLLIATMLISAPLLLWLSWSLARPARKLKMAADDVAKGNLRPHPELESGPQEF
                     LSTGNSFNQMISALDGMVTAQQRLISDISHELRTPLTRLQLATALLRRRHGESKELER
                     IETETHRLDSMINDLLVLSRSQHKNEILREHIKADELWGDILDDASFEAEQMNKTLDV
                     TSHPGPWPLYCNPSAIGSAFENIVRNALRYSNTHIAVDFKEENNGILITVDDDGPGVS
                     PADREHIFRPFYRTDEARDRETGGTGLGLAIVETAISQHKGWVKADDSPLGGLRLQIW
                     LPEHGR"
     misc_feature    1..21933
                     /note="antigen biosynthesis gene cluster"
     gene            2366..3895
                     /gene="wzx"
     CDS             2366..3895
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AXL96408.1"
                     /translation="MSNKRIFKNTISLYLRQIVIILITLYSMRVILNGLGLEDYGIYS
                     VVAGFVTLLAFLPGSMASATQRFFSFALGERDLSKLKKTFSVNLIMYAAIALLAYTLL
                     QTVGLGYINNYLKIPDTRFNAALELYHYTSLSFVISIFTAPFIAILIAHEDMHLYAFI
                     SVIDAILKLAIAISLAYVNYDLLAYYGAALLLISAFVACVYIFICIKKYAECQLKKLY
                     WSTTMLKEILGFTTWTLLGQLSTVFRNQAVTVLTNQMFTPSIVAARAIALNVSSQVAL
                     FSNNLNTGLYPPIIKSYAANEKNEMMNLVFNGSKLTFFLMWVFALPMMLEMKTILTIW
                     LKNPPPEAILFTQLAIVESLILAISMPLTTAARAPGKMALYEIILGSIQVAIFFISWL
                     FLSLGYSSEWVFYVAIAANILMFQIRLVLVKYLVSIPILPFYKKVVGPVLVILIISTF
                     LSIFLSRNLPNSLYSSFAVIVFSIISSIISMYYLGLDQYWRKRIINILASKFLKFRGA
                     K"
     gene            3892..4974
                     /gene="orf3"
     CDS             3892..4974
                     /gene="orf3"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="AXL96409.1"
                     /translation="MKILVLGGTGAIGVHLVKLLAEKNYQVYVTSRNKTDHTNNINYI
                     QGNAHNSDFLNSLLSQSWDAIVDFMVYSTPSFQQRYTQFLSSTKQYIFISSSRVYTDS
                     EQPITENSPRLLDTIKDQDYLNTDEYALAKARQENLLFGSTDNNWTIIRPYITYDDER
                     LQLGVLEKEDWLYRALHGRSIVTAKDIQTKLTTLTAGKDVARGICALIGNKLALGESF
                     HITNNQNISWQQISEIYLHVLAEHGLKVNLHEQNLDHFLSWRQGKYQVIYDRLFNRVF
                     NNEKISQFIDTSTFTPTQTGLKVCLENFINCTPYPFKSINWQEEALKDSLLNERTNLK
                     EISCTKQKIKYYLFKNLPRVGRLLTR"
     gene            4971..6719
                     /gene="orf4"
     CDS             4971..6719
                     /gene="orf4"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate binding domain-containing
                     protein"
                     /protein_id="AXL96410.1"
                     /translation="MKFYSTTEKNALIVISLLKAHGIRYIIASPGTTNTALIGSIQKD
                     PFFKIFSAADERSAAYIACGLSAETGEPVVISCTGATASRNYAPGMTEAYYRKLPVLA
                     ITSTQPMSRIGHHVAQVIDRSVISNDVANLSVTLPVVKDEDDFWDCEIKVNQAILELT
                     RRGGGPVHINLPTTYSLPFTEKENINCRVLNRFTQVSELPLLDSKTRISIIIGSHHRW
                     SEEATLAVENFCERYNAVVFCDHTSGYKGKNRVLISLAAAQELHSRTELKADITLHIG
                     EVTGDYSLVRMAGNDVWRISPDGEIRDTFRRLRYIFEMPEISFFQYYSEQASQTSTNE
                     YFQQCTDFLKTVQNKIPSIPFSNVWLASKLASKIPSGSAIHFGILNSLRAWNFYDLPS
                     TVTAFSNVGGFGIDGNVSSLLGASLASPNKLYYGVIGDLAFFYDLNAIGNRHVANNLR
                     ILLVNNGKGTEFRMYNHHAAHFNKDGDEFVAAAGHYGNKSSTLIKNYAENLGFEYFTA
                     NNKEEFETVYQRFIEPSITEKPMLFEVFTDSEDESKALQVMNKLEVSAEGKAKQTLKK
                     VLGPKGIDTVKKLIKR"
     gene            7049..8128
                     /gene="pt"
     CDS             7049..8128
                     /gene="pt"
                     /note="PT"
                     /codon_start=1
                     /transl_table=11
                     /product="putative polysaccharide pyruvyl transferase"
                     /protein_id="AXL96411.1"
                     /translation="MKIATLTLPFHPNYGAVLQAFALQKALQSLGHETYSLNIMRSSL
                     RSFPRNILSSLKRILTTGEFRENYKYGNKLFYEFINKELNLSNKIKYQRDFYRKDIQS
                     FDAYIVGSDQVWRPSYVIDINKFFLNFVPTNKIKISYAASFGTDKNEYTENNIISCKN
                     AIKQFKAVSVREKNGVQKCKDLFDTSSTEVLDPTFLLEKNDYAELIKKYPNSIGTKKI
                     VCYLLDATSQKRDLINKTFFGAYYINDGTSDYDKISIPDWLKLIQNAETVITDSFHGV
                     VFSIIFQKKFIAIGNTARGLERFSSLLTKLSLSDHLVIDSDLTMNNLLQLSQIVPNYS
                     ETERLLEKYKKISYSFIESNIINNH"
     gene            8150..9307
                     /gene="gt1"
     CDS             8150..9307
                     /gene="gt1"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AXL96412.1"
                     /translation="MKKILIITDICISQKHNAGNKNALLALCEFLRMKNYTIDIINFH
                     YSKPDSEDFKLFTIYHYPDFLNLIYRKTLEKLKLKPKLLDYKKSFFRKLILRLCIKKN
                     YDAIFIEYIENHHLINECRRFSSNIICDLHDVMYLRKQSFLENNDAPKKENLNISLKE
                     ETDIINKFNAVLAIEESEKNFLIENNVNSTVLLCKRTIVKNNILKIKTPILESVNIGF
                     IGSAAEFNITTILSFIAEIWNPYLSSNNYTLIIGGNVCNHLIKSNTIIKGNYKILGRI
                     SEIEDFYSKIHLSINPVISGSGFKTKNAESLSYGVPIITSMNGIKGFESINERYCKTI
                     LEHTSSEWICHIEKIKSDFFSDYNLKIHCHDHYNEVFNIKNNFKELEDYLS"
     gene            9325..10359
                     /gene="wzy"
     CDS             9325..10359
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AXL96413.1"
                     /translation="MYLFCVLFSLVENKKNTYSSKLFFLLIIYIFLLVIATLKPLGFG
                     FDDLNYYTVISQQEREISNPYGWEPGFMLLIIASSWFEDYSFIALNIFVLTICFILNG
                     YVFYKLSPLISIAFLWYFSHLFFYKEITQLRIAVAYSIVLFGFYFLYLEKNKKFLFLI
                     LLAYLFHVSSLISLIAYLFVKLKKKHILSFIIIAMIISELGLVDAIIIKLSHLFLNEA
                     SFNSYILDKSGFAKELNPLNPTTVKYIIFSIFFYYYSVKLKDRTFDFLLKIYMIAPLW
                     IILFSSFGTLASRPATIFSIVECILISNFAYNCYKNSIITKILIVFLSITLLLLNIVV
                     IKPVDMDLIY"
     gene            10361..11353
                     /gene="gt2"
     CDS             10361..11353
                     /gene="gt2"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AXL96414.1"
                     /translation="MRISCNKVIHIVPRNTNAGPVNVARDIVYGLNKKNIKATLFYLR
                     SKDNYGLISSFATLFSVLRKSKDIEVLHSHGIFPDLFCFFLSFFFNFKWISTIHADPE
                     EDLKFIYPKTYKIVCCFWRLILKKAKKAVYLTEYIYSKQKSQNKLFIHNSRLIEDLKI
                     NSLPNKCGLKRLGFCGALIERKNIKNLVLNFPNNSNYSLIVSGDGPLKSELKSIYKKN
                     ITYIGHNDDLSYFWSSIDILILPSFAEGVPLVAIEAIARGIPLILMNLDNYNGVFTDN
                     EAFFISNINQDSLIFAIEHIYNNYEDYHLGAISAYAHNFNFANWIEKYIVLYSE"
     gene            11397..12809
                     /gene="manC"
     CDS             11397..12809
                     /gene="manC"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanyltransferase"
                     /protein_id="AXL96415.1"
                     /translation="MSDLLPVILAGGSGSRLWPLSRSLYPKQFISLTSKKTMLQETIA
                     RLKNIEHQPPLLICNEEHRFIVAEQLRQENFKHSGIILEPVGRNTAPAIALAAIKAMQ
                     NGDDPLLLVLAADHVIQDQAAFTKIIENAIELAKQGALITFGIVPTAPETGYGYIKKG
                     HLVNESTFQVERFVEKPDLNTAEQYIASNEYLWNSGMFLFRASCYANELKKHAPEILS
                     NCELAIQNSLSDLDFTRINAEIFEACPEDSIDYAVMEKADNVFVVPMDAGWSDVGSFS
                     SLWEVSLKDQQSNVIIGDVLTENTKNSYVYSQSKLVSTVGVDNLVIIETKDAVLVANK
                     DHVQDVKSIVNQLKQAGRSECEQHREAYRPWGTHDEIAQGERFIVKHLKVKPGEKTAL
                     QIHYHRAEHWIVVQGTAKVTNNNKNYILGENESTYIPIGSPHQIENPGKIDLQLIEVR
                     SGNYLAEDDIVRIKEYGLDD"
     gene            12802..14277
                     /gene="manB"
     CDS             12802..14277
                     /gene="manB"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="AXL96416.1"
                     /translation="MTNPLDILNDDIIMNSYNVIKNSGIQFGTSGARGLVTQFTHEAC
                     SAFTHAFLSSIKSKFNFCQVAIAIDNRPSSEFIATVCIDAIKKQGFEPLYYGVIPTPA
                     LANTAMQSNIPCIMVTGSHIPFDRNGLKFYRPDGEITKTDELEILNSNVEFELSPTLA
                     PLLPVNPLATEQYIQRYRSIFDEKLLEGKRIGIYEHSSAGRDIYPVLFKQLGAEVISL
                     KRSDVFVPIDTEAVSEEDKIRAQNWSKLYGFDALFSTDGDGDRPLVADENGVWLRGDI
                     LGLLCSLEMGIEALAIPVSCNTIISKTEQFKCVKQTKIGSPYVIEELTNLAQTYSKIA
                     GFEANGGFLLGSDILINNKPLTALPTRDAVLPFLMLLSAAKKMSISSLVNTLPQRITF
                     SDRIQNFATEKSKSIIEKAASNPDKLLSDLGFSDARILEINTIDGLRMTLSNSNIIHL
                     RPSGNAPELRCYAEANSAEIAQSIVTQTLTRLQHFSSKAFN"
     gene            14393..15211
                     /gene="gt3"
     CDS             14393..15211
                     /gene="gt3"
                     /note="GT"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AXL96417.1"
                     /translation="MINFSVLLSVYKNERAKYLNNALESIYKDQILKPTEIILVQDGP
                     LTEDLYNIIKIWKNELADLLKIIDLPKNVGLGNALNIGLRECSYEWVMRMDTDDISMP
                     KRFLTQIEYIKDHPNIDLIGGIIEEFSEDLSTSLGKRTVPLDSVNIRKQSKKLNPLNH
                     VTVCFKKSAILSVGGYQHHLFMEDYNLWLRLIAAKYNIINLNDIFVQVRAGDGMITRR
                     KGLSYIKSEIQLAKLKRDLKIDGFLSSNMILLSRCLARILPNSLLIHLYKSLRK"
     gene            15221..16168
                     /gene="gne"
     CDS             15221..16168
                     /gene="gne"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="AXL96418.1"
                     /translation="MLTIIGGSGFIGTRLSNQLKSQNIDFKIVDIEKSEAHPEKWEFG
                     DVTKPETLIEPLKGSDVIINLSAKHKDNVHPISLYYEVNVDGAKNVCDVAEQLGIKHI
                     VFTSSVAVYGFVEKETGEDGEYHPFNHYGKSKLEAEYVYDAWQAKSADNILVTIRPTV
                     VFGENNRGNVYNLFRQIASGRFLMIGSGNNQKSMAYVENIAAFITFATTFTEGKHVFN
                     YIDKPDFTMNELTTVICGALNKPKSNIRIPYPVGILGGYCFDVLSKLTGKEFPVSSIR
                     VKKFCARTQFKSNYIGNTSFVPPVTLEQGIANTVQYEFK"
     gene            16219..17241
                     /gene="galE"
     CDS             16219..17241
                     /gene="galE"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactose 4-epimerase"
                     /protein_id="AXL96419.1"
                     /translation="MSNPSVLVTGGLGYIGSHTCVQMIQQGIQPIILDNLHNANLEVL
                     NRIETITGAKPTFYQGDVRDKSILDTIFAQHSISSVIHFAGLKAVGESVQKPIEYYDV
                     NVNGTLVLVQSMRQAGVKSLIFSSSATVYGDPEEVPLTENAKVGGTTNPYGTSKYMVE
                     QILTDLHIAESEWSLTLLRYFNPVGAHQSGLIGEDPQGIPNNLAPYVAQVAVGRHKEV
                     MVFGDDYPTPDGTGVRDYIHVMDLADGHIAALTHTSQKSGLHIYNLGTGKGTSVLEVI
                     AAFGKAANKPIPYKIVARRPGDIAECWSSPEKALKDLQWKAQYSVQDMVNDSWRWQSK
                     NPNGYK"
     gene            17594..18742
                     /gene="wza"
     CDS             17594..18742
                     /gene="wza"
                     /codon_start=1
                     /transl_table=11
                     /product="putative polysaccharide export protein"
                     /protein_id="AXL96420.1"
                     /translation="MLIKYLIPIAASALIAGCQIVPGTYISTSEKTIINTGKHDINTL
                     VDIYPISPQLLNEMQIAPVIAKPNPQLEKQLATYDYRVGVGDVLAITVWDHPELTIPA
                     GSYRSAADSGNWVHSDGTMYYPYIGKVSVIGKTISEIRKLVSLRLAAYIETPQVDVSI
                     AAFRSQKMYVSGEVIKAGALPITNIPLTLLEAFNTAGGLTENADWNNVVLTRNGKEIK
                     ISLQSLVQYGDLTQNHLMQPNDVLYVPRNDAQKVFVMGEVEQPATLTIDRAGMSITEA
                     LSKSRGLNQTTASATGIFVIRPINKQVPNNHMPNELPPQKIAVIYQLDLSDATALVMG
                     TKFKLQPYDLVYVTAAPIVRWNRLITQLLPTITSYNLLTESTKRIYNW"
     gene            18748..19176
                     /gene="wzb"
     CDS             18748..19176
                     /gene="wzb"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AXL96421.1"
                     /translation="MFNNILIICMGNICRSPTGERLMQLFFPQKMIHSVGFIAPLNKP
                     ADNNAIRIAKNHNLSLEGHYSRRLTEPLCQSADLILVMENHHIQKLYQQFPQTRGKVM
                     LFGEWLNKSEIPDPYKHSDEMFEHVYQLMEQAASSWQGKI"
     gene            19204..21285
                     /gene="wzc"
     CDS             19204..21285
                     /gene="wzc"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wzc"
                     /protein_id="AXL96422.1"
                     /translation="MINKEKNQSLNADEIDLLALFKALQFNYLTISISTVIFIFIAGI
                     YCFMAAPIYQANATLQYDKVNQASLLDQMNDVMPFGNHANPVESEVEVIKSRMVLGKT
                     VSDLNLDIQISPSGLLPKLSRNTIAIDIGQYHLPSSLMDQPATLTYLNEHQYTLAIAG
                     ETYHGKIGFPIEQQGIRLLVNSFMAETGDKLTLIKNDRFSTIENLRSRISINELGKST
                     GIINLSIKGLNKQENTKILDNIIQNYIDQNIEHKKKATDNSLVFLENYLPQIKSKLDH
                     YENQLNAFRKKNESIDLSLEAKSALESALQIEEKLNELTFKEVEIQQLYTRNHPAYQS
                     LIDKRQTLLLEKERISKNIQQLPNTQQQIVRLTRDVESEQAIYNQLVAKQQELSVLNA
                     GITSNMRIIDPAESQPAPIAPKKTLIMALASILGFIVGSGYVLAKECLNNKIKNSEDI
                     EALGVQVYAAIPFSFDEKRLQSNQHRKPLAIENPCDLAIEAIRSLRTSIYFSVMNQNN
                     NIVMLTSASPNIGKSFIASNIAVVLANAGKKILLIDADLRKGHIHKTFGLENKSGLSE
                     FLSQHNPDPIIIHKQVIDNLDIISRGKSVSHSSELLMSEQFKHLLDSLKHQYDMVLLD
                     TAPIFAVTDPAIIGKYAGTSLLIAHYDVSTVKELERALKHFAQNNIEITGAILNGIHK
                     KSEDYRYVYQY"
     gene            21430..21933
                     /gene="yibK"
     CDS             21430..21933
                     /gene="yibK"
                     /codon_start=1
                     /transl_table=11
                     /product="putative tRNA/rRNA methyltransferase"
                     /protein_id="AXL96423.1"
                     /translation="MPHIVLFEPEIPPNTGNIIRLCANTGFSLHLIHPLGFTWDDKRL
                     RRAGLDYSEFADIKHHHDYYAFLESEGLNPDNNQSPTGARVFALTTKGKPSHSNVSYR
                     EDDYLMFGPETRGLPPYVLDNMPIEQKIRIPMLAESRSMNLSNSVAVVVFETWRQLGY
                     PGALLKD"
BASE COUNT     7208 a   4083 c   3789 g   6853 t
ORIGIN
        1 atgatcaaca gcttaaccgc tcgaatattt gcgattttct ggtttaccct cgcactcgtc
       61 ttaatgctcg tgctgatggt gcccaagctc gactctcggc agctcactgt cctgatggaa
      121 agtgagcaac gccaagggga tatgcttgaa cagcatatcg aagctgaact cgcccaagca
      181 cccatgaacg acctactttg gtggcgacga atctctaacg ccatcaaaaa atgggcgccc
      241 ccaggtcaac gcttgatcat tgtgactagc gaaggtcggg taattggtgc aatgccgagt
      301 gaaatgcaag tgatccgtaa ttttattggt caatccgata atgcggacca cccgaagaag
      361 aaaaagtatg ggcgcgcaga aattttgggc ccattttcga ttcgagacgg tgaagatcac
      421 taccaactgt atttagttcg accggcgagt agtccacaat cagactttat taacctcttg
      481 tttgaccgac catttttact cttgattgcc accatgttaa tcagtgcacc actattatta
      541 tggttatcat ggagcttggc tcgtcctgcc cgtaaattaa aaatggcggc agatgatgtg
      601 gcaaaaggta atttacgtcc gcatcccgag ctagaatctg gtccgcagga atttttatct
      661 acgggcaaca gtttcaacca aatgatcagt gcgttagatg gcatggtcac tgcccagcag
      721 cgacttattt ctgatatttc gcacgagctg cgtaccccgc tcactcggct acagctggcg
      781 actgcattat tacgtcgccg ccatggtgag agtaaagagc tggagcgcat cgaaacggaa
      841 actcaccgtt tagacagtat gatcaacgac ctactcgttt tatctcgcag tcagcacaaa
      901 aatgaaattc tccgcgaaca catcaaagct gatgagttat ggggagatat tctggatgat
      961 gcgagtttcg aagcagagca gatgaataag acactggatg tgacatcgca cccaggtcca
     1021 tggccgttat attgcaatcc atccgccatt ggcagtgcgt ttgaaaacat cgtgcgtaac
     1081 gcacttcgct attcaaacac tcatattgcg gttgatttca aagaagaaaa taacggcatt
     1141 ctgattactg tcgatgatga tggacctggt gtcagcccag ctgaccgtga gcacatcttc
     1201 cgtccgttct atcgtacaga tgaagcgcga gacagagaaa ctggtggcac agggcttggc
     1261 ttagcaattg ttgaaacggc gatctcccag cataaaggct gggtgaaagc ggacgacagc
     1321 ccactgggcg ggttacgcct acagatttgg ctgccagagc acggtcgtta attttctctc
     1381 cttattgaga ttgaggtctt tggtgctgat gtgccaaaga cctttttata tatccgccat
     1441 atattcctat catattccga caaatattcc tttcatcgta caaagctgta gataattaat
     1501 cttccaacat aaactaaatg attatattaa ttcctcaatc gtttgatgat atttgcatat
     1561 tcgggtttgc tgcataaact aataagtaac aaaaatgctc agacaattct tataaatatt
     1621 atatttcaac aacttcatca ttgttcgagt atttatcttt atctacacca tacgagcgtg
     1681 ttcttctgaa atattaataa catacatcaa gtcacacgtg tcattatcat tattttttat
     1741 actattcaac cgtgtacaga tttttctttg actaatgctt caaccgctat ccactattaa
     1801 ggtttttatc aatatatcga ccaatctcaa actttacact taaaatggaa tgatatgcta
     1861 tagaatgacg agttaactcc agataatgac gcagaaattc tacgcacagt agtgatttct
     1921 aggcgcctca catcgatagt ccccccgaga ctttagtgct attattaagg gcttttgatt
     1981 gatcgtgctt acggcacgag ccaactgata agagaaggcg gtcataagca gtgtttatta
     2041 attgagcgat tttgtaaaaa atgcagtatt ttcaattaat aagtactaaa attgaaaatc
     2101 taatggcgct ctgggacccg ataacccagt gcggtagcta tgggtgtttg ttgatatatt
     2161 catttttgaa tgattaatgt gaactaagca tgcaagaata gtaaaaagat aatatcacca
     2221 aaatctatct aattagattc aaatcttaaa gtcgaaccaa tttttaatta tttatataga
     2281 gcattgttgt atttaaattt aacttctata aaaaaataat ttatggttca taaattattt
     2341 atatataaat taagctttca cttccatgtc aaataaaaga atcttcaaaa atacaatatc
     2401 tctttacctt cgccaaattg ttattatttt aattacttta tattctatga gagtaatttt
     2461 gaatggatta ggcttagagg attatggaat ctacagtgta gttgctggtt ttgttacttt
     2521 acttgcattc ttacctggta gtatggctag tgctactcaa cgctttttct cttttgctct
     2581 aggtgaaaga gatctatcta agttaaaaaa aactttcagt gtgaatctaa ttatgtatgc
     2641 tgctattgct ttattagcgt ataccttatt acagaccgta ggccttggat atattaataa
     2701 ttatttaaaa ataccagaca cacgctttaa tgctgcacta gaactttatc attacacttc
     2761 tctatcattc gtcatttcca ttttcactgc accttttata gcaattttaa ttgctcatga
     2821 agatatgcat ctttacgcat ttatttcagt aattgatgct atcctaaaat tagctattgc
     2881 tatttcttta gcttatgtca attatgattt actcgcctat tatggagcgg ctctattgct
     2941 catatctgct tttgttgcat gtgtttatat ttttatatgt atcaagaaat acgctgaatg
     3001 ccagctaaaa aaattatact ggagcaccac aatgctcaaa gaaattttag gctttactac
     3061 ttggacccta ttgggacaat taagcactgt ttttagaaat caagcagtga ctgttttaac
     3121 taatcaaatg tttactccta gcattgttgc tgctcgcgca attgcattaa atgtttccag
     3181 ccaagttgct ttattttcta ataatttaaa tactggattg tatcctccta ttattaaatc
     3241 ttacgcagca aatgaaaaaa atgaaatgat gaacttagtg tttaatggtt ctaagctcac
     3301 tttttttctg atgtgggtat ttgcattacc catgatgctt gaaatgaaaa ctattctgac
     3361 catttggtta aagaacccac cacctgaagc tattcttttt actcaactag caattgtaga
     3421 atccttaata ttagcgataa gtatgccatt aaccaccgca gctagagctc ccggtaagat
     3481 ggcattatat gaaataatat taggtagcat tcaagtagca atctttttta tttcatggct
     3541 gtttttaagt ttaggttact cttctgaatg ggtattttat gtcgccatcg ctgctaatat
     3601 tcttatgttt cagatacgat tagtcttagt aaaatatcta gttagtatac caattttacc
     3661 attttataaa aaggttgtag gcccggtatt ggtaatactc attatttcaa cctttcttag
     3721 tatattttta tcaagaaatc ttccaaatag tttatattct tcttttgccg ttattgtatt
     3781 ttcaattatt agctcaatta tttcaatgta ctatttagga ttagatcagt actggagaaa
     3841 aagaataatt aatatattag ccagtaaatt tttaaaattc agaggggcaa aatgaaaatt
     3901 ctagttctag gtggaacagg tgctatagga gttcatcttg taaagctctt agcagagaaa
     3961 aactatcaag tctatgtgac ttcacgcaat aaaaccgatc acaccaataa tattaattat
     4021 attcaaggta atgcccataa ttcagatttt ctcaatagct tattaagcca aagctgggat
     4081 gcgattgtag attttatggt ctactctaca cccagttttc aacaacgata tactcaattt
     4141 ttgagctcta caaaacagta tatttttatc agttcgtccc gtgtttatac cgattcagaa
     4201 cagccaataa ctgaaaactc ccctcgttta ctagatacta taaaagacca agactattta
     4261 aacactgatg aatatgcttt agcaaaagca agacaagaaa atctattatt tggtagtacc
     4321 gacaataatt ggaccattat ccgcccttac atcacatacg atgatgagag gttacaactc
     4381 ggtgtgcttg aaaaggaaga ttggctatat cgtgcattac atggacgcag tattgttaca
     4441 gcaaaagata ttcaaaccaa attaacgaca ctcaccgcag gcaaggatgt tgcgaggggg
     4501 atttgtgcat tgatcggaaa caagcttgca ttaggggaat catttcatat aacaaataac
     4561 caaaatatta gctggcagca aatatctgaa atttacctac atgtactagc tgaacatggg
     4621 cttaaagtga acttgcacga acaaaattta gaccattttt tatcatggcg acaaggcaaa
     4681 taccaagtta tttacgatag gttatttaac cgagttttca ataacgaaaa gattagccaa
     4741 tttatagata cctcaacttt tactccaaca caaactggct tgaaggtatg tcttgaaaac
     4801 tttattaatt gcacacctta cccatttaaa tcaataaatt ggcaagagga agcacttaaa
     4861 gatagtttgc tcaatgagcg aacgaattta aaagagatat cttgtaccaa acaaaagatt
     4921 aaatactatt tattcaaaaa cctaccaaga gtaggaaggc tgctaacacg atgaaattct
     4981 attcaacaac tgaaaaaaat gcgctaattg ttatctcatt actcaaagcc cacggcattc
     5041 gttatatcat tgcgtcaccc ggtacaacaa atacggccct catcggcagc attcaaaaag
     5101 atccattctt caaaattttt tcggctgctg acgagcgttc agccgcttat attgcttgtg
     5161 gtttatctgc agagactggt gaaccagtgg taattagctg taccggagct accgcctcaa
     5221 gaaactatgc ccctggtatg acggaagctt actatcgcaa acttcctgta ttagctatta
     5281 cgtcaactca gccaatgagc cgcattggac atcatgttgc tcaggtaatc gaccgcagtg
     5341 ttatttcaaa cgatgtagcc aatctcagtg taaccttgcc agtcgtaaag gatgaagatg
     5401 atttttggga ttgtgagatc aaagttaacc aagccatttt agagttgact cgacgtggtg
     5461 gaggtcctgt acatatcaat ttacccacta catacagcct accttttact gaaaaagaaa
     5521 atatcaattg cagagtgttg aatcgcttta ctcaagtaag tgagctacca ttgcttgact
     5581 caaaaactcg tatttcgatc ataatcggct ctcatcatcg ttggagtgag gaagctacac
     5641 ttgcagtcga aaatttttgt gaacgatata atgctgtcgt tttttgtgac cacaccagtg
     5701 gctataaagg taagaaccga gtactaatct cacttgcagc tgctcaagag ctccattcaa
     5761 gaacagagct taaagcggat ataaccttac atataggaga agtgactggt gattattctt
     5821 tagtaagaat ggctggaaat gatgtttggc gtattagccc tgatggtgaa atacgagata
     5881 cattccgtag gcttcgttat atatttgaaa tgccagaaat atcatttttc caatattatt
     5941 ccgaacaagc atcccaaaca tcaaccaacg aatactttca acaatgtact gattttttaa
     6001 aaacagtaca aaataaaata cctagcattc ctttctctaa tgtttggtta gcatccaaac
     6061 tagcatcaaa gataccatca ggttctgcta ttcattttgg gattttgaat agtttaaggg
     6121 cgtggaactt ctatgatctt cccagtacag taaccgcatt ttcaaatgtt ggaggctttg
     6181 gaatagatgg aaatgtatcc tctttacttg gcgcatcttt agcaagtcct aacaaacttt
     6241 attatggtgt catcggtgac cttgccttct tctatgacct caatgcaata ggcaaccgcc
     6301 atgtagcaaa caatttgcga attcttcttg ttaataatgg gaaaggaaca gagtttagaa
     6361 tgtataatca tcatgctgcg cattttaata aggatggtga tgaatttgtt gctgccgcag
     6421 gacattatgg aaacaaatct agcactctta ttaaaaacta tgctgaaaat ttaggctttg
     6481 aatattttac agcaaacaat aaagaagaat ttgaaaccgt ttaccaacgg tttattgaac
     6541 caagtattac agaaaaacca atgctttttg aagtattcac tgatagtgag gacgaaagta
     6601 aagcacttca agtaatgaat aaactagaag tcagtgcaga aggtaaagcc aagcaaacac
     6661 ttaaaaaagt cctcggtccc aaaggcattg atacagtaaa aaaattaata aaaagataaa
     6721 aattagaata ttagctctgc aaccctccga taattatcgt gaactccaga gctatattca
     6781 atatatcctc taataatatt gacactagta tttaccttag cacgagcaaa atacataaaa
     6841 aatatttatc ttttgattta aattaactca aaacacccct atttccgatt ttattgtcat
     6901 tattatagaa attaatacta ctctgcatat tcaattagac taaaaatgtt cttatctttt
     6961 tacaactatc atataggctg cttttagttt aaaagtaaac taataccaaa atatataaat
     7021 aagccattta atttttgaga gtttcattat gaaaattgcc acattgacgt taccttttca
     7081 tcctaattat ggagcagtac tacaagcttt tgcacttcaa aaagcccttc aaagcttagg
     7141 acatgaaact tactcattaa atataatgcg ttcatcattg cgttctttcc ctcgaaacat
     7201 tctgtcatca ttaaagagaa tattaacaac aggagaattt agagagaatt ataaatatgg
     7261 aaataagcta ttttatgagt ttataaataa agagcttaac ctatcaaaca aaattaaata
     7321 tcagcgagat ttttatcgta aagatattca aagctttgat gcttacatag ttggcagcga
     7381 tcaagtatgg cgaccatcat atgttataga tataaataaa ttctttctaa attttgtacc
     7441 tactaataaa attaaaattt catatgctgc atcctttggc actgataaaa atgaatatac
     7501 agaaaataat ataatttcct gtaagaacgc aatcaagcaa tttaaagctg tttctgtaag
     7561 agaaaaaaat ggagtacaaa agtgtaaaga cttatttgat acttcaagta cggaagtttt
     7621 ggacccaaca tttctattag aaaaaaatga ttatgccgag ttaatcaaga aataccccaa
     7681 tagtattggt actaaaaaaa tcgtctgtta tttgcttgat gcaacatcgc agaaaagaga
     7741 tttaataaat aaaacatttt ttggtgcata ttatattaat gatggcacta gcgattatga
     7801 caagattagc attccggatt ggttaaaatt aatacaaaat gcagagaccg taataacaga
     7861 ctcctttcat ggagttgttt tttctattat ttttcaaaaa aaattcattg caattggaaa
     7921 tacagccaga ggtttagaac gtttttcaag tctattgact aaattatctc tttctgatca
     7981 tttagttatt gactctgacc taacaatgaa taatttattg caactatcac aaattgttcc
     8041 taactactct gaaacagaga gattactaga aaagtataaa aaaatctcat attcattcat
     8101 tgagagtaat ataattaaca accattaaaa attacataac tttattgaaa tgaaaaagat
     8161 acttatcatt accgatattt gtatttcgca aaaacataat gcaggaaata agaatgcttt
     8221 attagcttta tgtgaatttc ttagaatgaa aaattatact attgatatta ttaattttca
     8281 ttactctaag cctgatagtg aagatttcaa attatttact atatatcatt atcctgattt
     8341 tttaaattta atatacagaa aaacactgga aaaactaaag ttaaagccta aacttttaga
     8401 ttataaaaaa tcttttttta gaaagctaat tctccggtta tgtataaaaa agaattatga
     8461 tgcaatattc attgagtata tagagaatca tcacttgata aatgaatgtc gtagatttag
     8521 ttcaaacata atatgtgacc tacatgatgt tatgtactta agaaagcaat cctttctaga
     8581 aaataatgac gctccgaaaa aagaaaatct aaacatctca ttaaaagaag aaactgacat
     8641 tataaataaa tttaatgctg tgttagccat agaagaaagt gaaaagaatt ttctaataga
     8701 aaataatgtt aactctactg ttcttctttg taaacgaact atcgttaaaa ataatatttt
     8761 aaaaattaaa actcccatat tagaatcagt taatataggt tttattggta gtgctgcaga
     8821 gtttaatatt acaactatac tttcatttat cgctgaaatc tggaatcctt atttgtcttc
     8881 taataattac actttaatta ttggtggtaa tgtttgcaac catttaatta aatcgaatac
     8941 gattataaaa ggaaattata aaatacttgg tagaatttca gaaattgaag atttttattc
     9001 taaaattcat ttatccataa atccagttat atcaggatca ggatttaaaa caaaaaatgc
     9061 tgaatcatta agctatggtg ttcctattat tacatcaatg aatggcatta aaggatttga
     9121 aagcattaac gaacgatatt gcaaaactat acttgagcat acctctagcg aatggatatg
     9181 tcatatagaa aaaataaaat cagatttttt ttcagattat aacttaaaaa ttcactgcca
     9241 tgaccattat aatgaagtgt ttaatataaa aaataacttc aaggaattag aggattatct
     9301 aagttgattt acgccttttg tttcatgtac ttattttgtg ttttattttc tcttgttgaa
     9361 aataaaaaaa acacttactc ttcaaagtta tttttcctat taataattta cattttcctg
     9421 ttagttattg caacattgaa accgctaggc tttgggtttg atgatttaaa ttactacact
     9481 gtaattagtc agcaagaacg cgaaattagc aacccttatg gttgggaacc tggctttatg
     9541 ctattaatta tagcttcatc ttggtttgaa gactattcat ttatagctct aaacattttt
     9601 gtacttacaa tttgctttat tttaaatggc tatgtttttt ataaactatc acctttaata
     9661 tcaatagcat ttctatggta cttttctcat ttattttttt ataaagaaat aacacagctt
     9721 aggattgcag tagcttactc tattgtatta ttcggttttt attttttata tcttgaaaaa
     9781 aataaaaaat ttttattctt aatactccta gcgtatttat ttcacgtgag ctctctaatc
     9841 tcactaattg cttatttatt tgttaaactt aaaaagaagc atatattatc ttttataata
     9901 atagcaatga ttatatcgga attaggacta gttgatgcta ttattattaa actatcccat
     9961 ctatttttaa atgaagcttc atttaattct tacatcctag ataaatctgg gtttgctaaa
    10021 gagctcaatc ctttaaaccc aacaacagtt aaatacatca tattttctat atttttttat
    10081 tattatagtg taaaactaaa agatagaaca tttgattttt tactaaaaat ttacatgatt
    10141 gctcccctat ggatcatcct tttttctagc tttggcacgt tagcaagtcg tcctgcaact
    10201 atattttcaa ttgttgagtg tattctgatt agtaacttcg cctataattg ttataaaaat
    10261 tctattataa caaaaatatt aatcgtattt ttatctataa ctttattatt gttaaacatt
    10321 gtagtaataa aacctgttga catggattta atatattaaa atgcgtatat cgtgtaataa
    10381 agtaattcat attgttcctc gaaatactaa tgcaggacca gtgaatgtag ccagagatat
    10441 agtttatggc ttgaataaaa aaaatattaa agccaccctt ttttatctta gaagtaaaga
    10501 taattacggg ttgatttcta gctttgcaac ccttttctct gttttacgaa aaagcaaaga
    10561 tattgaagtt cttcattctc atggtatatt ccctgacctt ttttgctttt ttttatcttt
    10621 tttctttaac tttaaatgga tatctactat tcatgcagac ccagaagagg atttgaagtt
    10681 tatttatcca aaaacatata aaatcgtatg ctgtttttgg aggctgattt taaaaaaagc
    10741 aaaaaaagca gtttatctca cggaatatat atattcaaaa caaaaatcac aaaacaaact
    10801 ctttatacat aattcacgct taattgagga tttaaaaata aactcattac ctaataagtg
    10861 tggtctaaag agattaggat tctgtggtgc cttgattgaa agaaaaaata taaaaaactt
    10921 ggttttaaat ttccctaaca attctaatta ctcccttatt gtctccggag atggcccact
    10981 taaaagcgaa ttaaagtcta tatataaaaa aaatattact tatataggcc ataatgatga
    11041 cctaagttat ttttggtcta gtatagatat attaatatta ccttcctttg cagaaggtgt
    11101 cccattagtt gcaatagaag ctattgctag aggtattcct ttaatcttaa tgaatctgga
    11161 taactacaat ggagtattca ccgataatga ggcatttttt atctcaaata taaaccaaga
    11221 ttcattaatc ttcgcaatag aacatatcta caataattat gaagattacc atctcggagc
    11281 tatttctgct tatgctcaca attttaattt tgctaattgg atagaaaaat atattgtatt
    11341 atattcagaa tgataaaacc tctaccccca tatttatata ataaaggtaa cctctaatgt
    11401 cagatttatt gccagttatt ttagctggag gttctggtag tcgtttatgg ccactttctc
    11461 gtagcttata tccaaaacag tttattagcc tcacgagtaa aaaaacgatg ctacaagaga
    11521 ctattgctcg cctaaaaaat atagagcacc agcctccgtt acttatttgt aatgaagagc
    11581 accggtttat tgttgcagaa caattgagac aagagaattt taaacatagt ggcattattt
    11641 tagaacctgt tgggcgtaat acagctccag caattgcatt agcggcaatt aaagccatgc
    11701 aaaatggtga tgacccactg ctgcttgttt tagccgcaga tcacgttatt caagaccaag
    11761 ctgctttcac aaagattatt gaaaacgcaa tcgagctagc aaaacaaggg gctttaatta
    11821 cctttggtat tgttcccact gcgcctgaaa caggctatgg ttatatcaag aaaggtcatt
    11881 tggttaatga atctaccttc caagttgagc gttttgttga aaagcctgat ttaaatactg
    11941 ctgagcaata tattgctagt aatgagtatc tttggaatag cggtatgttt ttatttagag
    12001 catcttgcta tgctaacgag ttaaaaaaac atgctcctga aatcctttca aactgcgaat
    12061 tggcaattca aaattcgctc agtgacttag acttcactcg tatcaatgct gaaatttttg
    12121 aagcatgtcc agaagactcc atcgactatg ctgttatgga aaaagcagac aatgtcttcg
    12181 ttgttccaat ggatgcgggg tggagcgatg ttggctcatt tagttcacta tgggaagttt
    12241 ctcttaaaga tcaacagtct aacgttatca ttggtgatgt tcttacagaa aatactaaaa
    12301 atagttatgt ctactcgcaa agtaaactag tctccactgt tggagttgat aacctggtta
    12361 ttattgaaac caaggatgct gtgcttgtcg cgaataaaga ccatgtccaa gatgtcaaaa
    12421 gtattgttaa ccagctgaag caagctggtc gtagtgaatg tgaacaacac agagaagcat
    12481 atcgcccatg gggtactcat gatgaaattg cacaaggaga acgctttatt gttaaacact
    12541 tgaaagtcaa acccggtgaa aaaaccgcac tacaaattca ttatcatcga gctgagcatt
    12601 ggatcgttgt acaaggtacc gctaaggtta ctaacaataa caagaactat attttaggtg
    12661 aaaatgaatc aacctatatc cctataggtt cacctcacca aatagaaaat cctggaaaaa
    12721 ttgaccttca attgattgaa gttcgttctg gaaactatct cgcagaagat gacattgttc
    12781 gcattaaaga atatgggtta gatgactaat cccctagaca ttcttaacga tgatataatt
    12841 atgaatagtt ataatgtaat taaaaactca ggcattcagt ttggtacaag cggcgcacgt
    12901 ggtttagtga ctcagtttac ccatgaagct tgctcagcct tcacccatgc attcctatca
    12961 agcatcaaga gtaaatttaa tttttgccaa gtcgctatcg caatagataa ccgccccagt
    13021 agtgaattta ttgcgacagt ttgtattgat gccatcaaaa aacaaggctt tgagccactt
    13081 tattatggtg ttatccccac accagccctt gcgaatacag cgatgcaaag taatattcct
    13141 tgcattatgg taacgggtag ccacattcct tttgatagaa acggtttaaa gttttatcga
    13201 cctgatggtg aaataacaaa gactgatgaa cttgaaattt tgaacagcaa tgtagaattt
    13261 gaactttcgc ctaccttagc tccattatta cccgtaaatc ctcttgcaac agagcaatac
    13321 atccagagat atagatctat cttcgatgaa aaactattag agggaaaacg tattggtatc
    13381 tatgagcact caagtgcagg tcgagatatt tatcccgttc tatttaaaca gctaggcgcc
    13441 gaagttattt ctttgaaaag aagtgatgta tttgttccga ttgatactga agctgtttct
    13501 gaagaagaca aaatcagagc acaaaactgg tctaaattat atggctttga tgcactattc
    13561 tcaacggatg gagatggcga ccgacctcta gtagccgatg aaaatggtgt atggctacga
    13621 ggtgatatac taggtttact atgttcatta gaaatgggta ttgaagcact agcgattccg
    13681 gtaagttgca atacaattat ctcaaaaaca gagcagttta aatgtgtaaa gcaaacaaaa
    13741 attggctcac cttatgtcat tgaagaactt actaatttag ctcaaaccta ctccaaaatt
    13801 gctggctttg aagctaatgg tggttttcta ctcggttcag atattctgat taataataaa
    13861 cctctcacag cattaccaac ccgcgatgcc gttttaccat tcctgatgtt attatcagcg
    13921 gcaaaaaaaa tgagtatttc ttctttagtt aatacattac cacagcgtat tacttttagt
    13981 gaccgtatac aaaactttgc aacagaaaaa agcaaaagca tcattgaaaa agccgcaagt
    14041 aatcctgata aattattgag cgatttaggc tttagcgatg cacgtatact agagatcaac
    14101 actattgatg gcttaaggat gacattgtcc aacagtaata ttatccacct aagaccctca
    14161 ggcaatgctc cagaactaag atgttatgct gaagcaaata gcgctgaaat agcgcaatct
    14221 atcgtgaccc aaacattaac taggcttcaa catttttcta gtaaagcgtt caactaaagc
    14281 atcataatcg ttaaagctaa aatgaaatag gcacacgaat atccttcatt attttagtaa
    14341 actttgctag ataatagtgg aatgaataaa tttacttttg tgatataact ctatgattaa
    14401 cttttctgtt ttattatccg tatataagaa tgaaagagcg aaatatctta ataacgctct
    14461 tgaaagtata tataaagacc aaattcttaa acctaccgaa attatattag tccaagacgg
    14521 acctcttaca gaagatctgt ataatataat taaaatctgg aaaaacgaat tagctgattt
    14581 attaaaaatt atcgaccttc ctaaaaatgt tggtctcggt aatgcactga atataggatt
    14641 gcgtgaatgt agttatgaat gggtaatgcg tatggatact gatgatattt ccatgccaaa
    14701 aagattctta actcaaattg agtatataaa agatcaccct aatattgatc ttattggagg
    14761 tatcattgaa gaattcagcg aagacctctc tacatcatta ggaaaacgta cagttcctct
    14821 agactcagtt aacataagaa aacaatctaa aaagttaaat ccattaaacc atgttactgt
    14881 ctgttttaag aaaagtgcaa ttttatctgt aggtggatat caacatcatt tattcatgga
    14941 ggattacaat ttatggctac gtcttattgc ggcgaaatat aacattataa atttgaatga
    15001 tatttttgtt caggttcgcg ctggcgatgg aatgatcaca agaagaaaag gcctatctta
    15061 tattaaaagt gaaatacaac tggccaaatt aaaaagagat ctaaaaatag atggcttttt
    15121 atcatccaat atgattcttc tttctcgctg cttagctcgt attctaccca atagtttact
    15181 tatacattta tataagtcgt taagaaaata aaggttcatt atgctaacaa tcatcggtgg
    15241 ttccggcttt atcggaacac gtctatcaaa ccaattaaaa tctcaaaata tcgatttcaa
    15301 aattgttgat attgaaaaaa gtgaagcaca tcctgaaaag tgggaatttg gtgatgtcac
    15361 caagcctgaa acgcttatcg agccactgaa gggtagtgat gtcattatta acctatccgc
    15421 aaaacataaa gataatgttc atcctattag cctttactat gaagtgaacg ttgatggtgc
    15481 caaaaacgtc tgtgatgtcg ctgaacaact gggtattaag cacattgttt tcacttcctc
    15541 agttgctgtt tatggcttcg ttgaaaaaga aaccggagaa gatggcgaat atcatccatt
    15601 taaccactat ggtaaatcta agttagaagc tgaatacgtt tacgatgcat ggcaggcaaa
    15661 atccgcggac aacatcttag ttactattcg tccaaccgtt gtatttggtg aaaataaccg
    15721 tggtaacgtt tataacttat tccgccaaat tgcgtctggt cgattcttaa tgatcggttc
    15781 tggtaataac caaaaatcaa tggcctatgt agaaaatatt gcggcattta ttacattcgc
    15841 aaccaccttc actgaaggga agcatgtatt caattacatc gataagcctg attttacgat
    15901 gaacgaatta acaacggtca tttgtggtgc tcttaataag ccaaaatcta atatccgcat
    15961 tccatatcca gttgggattt taggtggcta ctgttttgac gtgctttcta aactgacggg
    16021 caaagaattc ccagtgagta gtattcgtgt gaaaaaattc tgtgctcgta cacaatttaa
    16081 atccaattac attggaaata cctcttttgt tccacctgtt actttggaac aaggtatcgc
    16141 caatactgtg cagtatgagt ttaaataaac ctaatttatc ctaatctcaa ttttgagatt
    16201 tgtagacagg atttcaccat gagtaaccct agcgtattag tcaccggcgg tcttggctat
    16261 attggtagcc atacctgcgt acaaatgatc cagcaaggta ttcagccgat cattttagat
    16321 aacctccaca atgctaacct tgaagtactt aatcgcattg aaaccatcac gggagctaaa
    16381 ccgacgtttt atcaaggtga tgtgcgtgac aaaagcattt tggacaccat ttttgctcag
    16441 cattccatta gctcagtgat ccactttgcg ggtttaaaag cggtagggga atctgttcaa
    16501 aaaccgattg aatattacga tgtgaatgtg aatggcactt tggttttagt ccaaagcatg
    16561 cgtcaggcgg gtgttaaaag cttaattttc agctcatctg caacggtata tggtgaccca
    16621 gaagaagttc ctctgactga gaatgccaaa gttggtggta ccaccaaccc atatggcacc
    16681 agtaagtata tggtagaaca aatactgact gacctacata tcgcagaaag cgaatggtct
    16741 ttgaccttat tacgttactt caaccctgtt ggcgctcacc aatcaggctt aattggtgaa
    16801 gatccccaag gtatcccgaa taacctagcg ccatatgtcg ctcaagttgc agtaggtcgc
    16861 cataaagaag tgatggtatt tggtgatgat taccccactc ctgatggaac aggggtgcgc
    16921 gactatatcc acgtcatgga tttagccgat ggtcacattg cagcactaac ccataccagc
    16981 caaaaatcgg ggttacatat ttataatctt ggtacaggca aaggtactag cgtattggaa
    17041 gtgatcgctg catttggtaa agctgccaat aagccgattc catataaaat tgttgctaga
    17101 agacctggcg atattgctga atgttggtct agccctgaaa aagcacttaa agacctacaa
    17161 tggaaagcac aatattctgt acaagatatg gtgaatgata gttggcgctg gcaatcaaaa
    17221 aatcctaacg gctataaata accgttttga tcattactaa ggcgagcact cagctcgcct
    17281 tttttatatt taaaaatccc ccttctatac cccccgttcg aactctcttc cttaactctc
    17341 ttttcctcta aaaataacgc tctgatattt aaataaagtc ttaaaaataa ttccattctc
    17401 gtcattacac aaaaaacatc caaaaaatca ataacctttt ttattctatt atatttttat
    17461 ataagtgggt ttttcagaca aaatatttga atatcaatta agaattaaat tattatgcca
    17521 gccagaatta tatgtttgtg taacttcaat gtctgaaatg cacgctttcc tatcctgatt
    17581 tagggcgatt accatgttga ttaaatacct tattcctata gcagccagcg cgctcattgc
    17641 tgggtgccaa atcgtccctg gaacgtatat ttccacatca gaaaaaacca ttattaacac
    17701 tggcaaacat gatattaata cgcttgtgga tatctaccct atctccccac agttgctaaa
    17761 tgaaatgcag attgcccctg tgatcgccaa accaaatcca caactggaaa aacaattagc
    17821 cacttatgac tatcgggttg gcgttggcga tgtattggcc attacggttt gggatcaccc
    17881 cgagctcacc atccctgcgg gttcttatcg cagcgcagct gattccggaa attgggttca
    17941 ctccgatggc acaatgtatt atccctatat tggaaaagta tccgttatcg gaaaaacaat
    18001 tagtgaaata cgaaaattag tgagcctccg actcgccgcc tatattgaaa caccgcaagt
    18061 tgatgtcagt attgcggcat ttcgctcaca aaaaatgtat gtttctggtg aggtcatcaa
    18121 ggcgggagcg cttcccatca caaatatacc gctaaccctc ttagaggcat tcaatacggc
    18181 aggtgggctc actgaaaacg cagattggaa taacgtggtg cttacccgta acggcaaaga
    18241 aatcaagatc tcactacaat ccttagttca gtatggcgac ctaacccaga accacttaat
    18301 gcagcccaat gatgtgctat atgtgccccg caatgatgca caaaaagtat ttgtgatggg
    18361 agaagtcgaa caaccagcga ccctgacgat cgaccgtgca ggcatgagta ttaccgaggc
    18421 gctcagtaaa tccagaggac tcaatcaaac aacagcaagt gcgaccggta tatttgtgat
    18481 tcgccctatt aataagcaag taccgaataa tcatatgcca aatgagctac cgcctcaaaa
    18541 aatagcggtt atttatcagc tagatctatc cgatgcgacc gcattagtga tgggaaccaa
    18601 atttaaatta cagccttatg accttgttta tgtgaccgca gcgcctatcg ttcgctggaa
    18661 ccgtttaatt acccaactct tgccaaccat cacgtcatac aacctgttaa ccgaaagtac
    18721 taagcgtatt tataactggt aatacctatg ttcaataata tccttattat atgcatgggc
    18781 aatatctgcc gttcccccac tggagaacgc ttaatgcagt tatttttccc tcaaaaaatg
    18841 attcattccg tcggctttat cgcgccactg aacaaacctg cggataacaa tgctatccgt
    18901 attgctaaaa accataatct ctctttagag gggcattatt ctcgccgttt aactgaaccc
    18961 ctatgccaat cagcagactt aatccttgtg atggaaaacc accatatcca aaaactctat
    19021 caacagtttc cgcaaactcg cggcaaagtc atgttattcg gtgaatggct aaacaaatct
    19081 gaaatccccg atccctataa acatagtgat gagatgtttg aacatgttta tcaacttatg
    19141 gaacaagcgg ccagttcctg gcaagggaaa atttaatttt taactgatgg caaaactaac
    19201 ataatgataa ataaagaaaa aaaccaatcg ctaaatgcag atgaaatcga ccttctcgcc
    19261 ttatttaaag cattacaatt caattattta acaataagta tttcgactgt tatttttata
    19321 ttcattgcag gaatatattg ttttatggct gcccccatct atcaagctaa tgccacgctg
    19381 caatatgaca aggtcaacca agcatcatta ttagatcaaa tgaatgacgt gatgcccttc
    19441 ggcaatcatg caaatccggt agaatcagaa gttgaagtga taaaatcccg catggtttta
    19501 ggtaaaacag tctcagatct taatttagat attcaaatat cgccatcagg gctgttgcct
    19561 aaactgagca gaaatacaat cgccatcgat attgggcaat atcatttacc ctctagctta
    19621 atggatcagc cagcaacact aacgtatctc aatgaacatc aatatacttt ggctattgca
    19681 ggggaaactt atcacggcaa aattggcttc cccatagagc aacagggtat tcgcctatta
    19741 gtgaattcat tcatggcaga aacgggagat aaactgaccc tgataaaaaa tgatcggttt
    19801 tccactatcg aaaatttgcg tagtcgtatc agcattaatg agcttggaaa aagtactgga
    19861 atcattaatt tatcgattaa gggactcaat aagcaagaaa ataccaaaat actggataac
    19921 attattcaaa attatatcga tcaaaatata gagcataaga aaaaagccac tgataactcg
    19981 ttggtctttt tagagaatta tttgccccaa ataaaaagta agcttgacca ttatgaaaat
    20041 caattaaatg cttttcgtaa aaaaaatgag tctattgacc tctctttaga agcgaaatcc
    20101 gcacttgaaa gcgcattaca aatagaagaa aaactcaacg agctgacgtt caaagaagtg
    20161 gaaattcaac agttatatac ccgtaatcac cctgcttacc aatccttgat agataaacgc
    20221 caaacattac tactcgaaaa agaacgtatc agtaaaaata tccaacagct gccaaatact
    20281 cagcaacaga ttgttcggct aactcgagat gttgaatcag aacaggcaat ttataatcaa
    20341 ttggttgcga agcaacaaga actcagtgta ctcaatgctg ggataacctc taacatgcgc
    20401 atcattgacc cggcagaatc gcagcccgcg cctattgcgc cgaaaaaaac cttaattatg
    20461 gctttagcat ccattctagg tttcattgtc ggtagcggtt atgtgctcgc caaggaatgc
    20521 ctgaataata aaattaaaaa ttctgaagat atcgaagcgc tcggtgttca ggtttatgca
    20581 gccattccat tttcttttga tgaaaaaaga ttacagtcta atcaacatcg aaagccatta
    20641 gcgattgaaa atccatgcga tcttgcaata gaagccatcc gttcattaag aacgagcatc
    20701 tatttttcag tcatgaacca aaacaataac attgtcatgc tgactagcgc gtcgcccaac
    20761 attggcaaaa gcttcattgc ttcaaatatc gctgttgtcc tcgcaaatgc aggtaaaaaa
    20821 attctgctta ttgatgccga cttacgtaag ggccatatcc ataaaacttt tggcttagaa
    20881 aataaatcgg ggctttcaga gttcttatct caacacaatc ctgacccaat cattattcat
    20941 aaacaagtta ttgataattt ggatattata agccgaggaa agagtgtttc tcactcttcc
    21001 gagctactca tgagcgaaca atttaaacat ttattggact cgcttaagca tcaatatgac
    21061 atggtactgc ttgataccgc gcctattttt gcagtaaccg atcctgcaat tattggtaaa
    21121 tatgcgggaa cctcgctcct aattgcacat tatgatgtca gtaccgtgaa agagctcgaa
    21181 cgtgctctta aacattttgc tcaaaataat attgaaatta caggtgcgat cctcaatggt
    21241 attcacaaga aatcagagga ttatcgctat gtttaccagt attaatggga tggcgagcga
    21301 ttagctcgcc tttttatacc ctcaaattat tctgtttcag cctcgtgcca tgcaatagat
    21361 gcatctttcc aaatttgcgc gtaaactctg catcatcttt tttcatctag accaatagcc
    21421 attaacgtta tgccacatat tgttttattc gaacctgaaa tcccacccaa tacgggcaac
    21481 atcatccgct tatgtgctaa tacaggtttt agcttacacc ttattcaccc gctgggtttt
    21541 acttgggatg acaaacgctt gcgccgcgca ggactcgatt acagtgagtt tgcggacatc
    21601 aaacatcacc atgattatta tgcattctta gaaagtgaag ggttaaatcc tgataataat
    21661 cagtcgccaa caggcgctcg tgtgtttgcg ttgacaacca aaggtaaacc gagccacagc
    21721 aatgtgagct atcgggaaga tgattatttg atgtttggac cagaaactcg tggcttgccg
    21781 ccttatgttc tcgacaatat gccaatcgag cagaaaattc gtatcccgat gctagcggaa
    21841 agccgcagta tgaatctttc taactcagtt gccgttgtgg tattcgaaac ttggcgccag
    21901 cttggatatc cgggtgcgct gctgaaagac taa
//
