LOCUS       AF498403               24949 bp    DNA     linear   BCT 13-JUN-2002
DEFINITION  Pseudomonas aeruginosa serotype 012 putative O-antigen biosynthesis
            gene cluster, partial sequence.
ACCESSION   AF498403 AC104722
VERSION     AF498403.1  GI:20559806
KEYWORDS    .
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (bases 1 to 24949)
  AUTHORS   Raymond,C.K., Sims,E.H., Kas,A., Spencer,D.H., Kutyavin,T.V.,
            Ivey,R.G., Zhou,Y., Kaul,R., Clendenning,J.B. and Olson,M.V.
  TITLE     Genetic variation at the O-antigen biosynthetic locus in
            Pseudomonas aeruginosa
  JOURNAL   J. Bacteriol. 184 (13), 3614-3622 (2002)
   PUBMED   12057956
REFERENCE   2  (bases 1 to 24949)
  AUTHORS   Raymond,C.K., Sims,E.H., Kas,A., Spencer,D.H., Kutyavin,T.V.,
            Ivey,R.G., Zhou,Y., Kaul,R., Clendinning,J.B. and Olson,M.V.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-APR-2002) Genome Center, University of Washington,
            Box 352145, Seattle, WA 98105-2145, USA
COMMENT     On May 13, 2002 this sequence version replaced gi:17975251.
FEATURES             Location/Qualifiers
     source          1..24949
                     /organism="Pseudomonas aeruginosa"
                     /mol_type="genomic DNA"
                     /serotype="012"
                     /db_xref="taxon:287"
     CDS             <1..104
                     /note="ORF_1; C-terminal coding region of rpsA"
                     /codon_start=3
                     /transl_table=11
                     /product="RpsA"
                     /protein_id="AAM27582.1"
                     /db_xref="GI:20559807"
                     /translation="EKDAMKELRKQEVESAGPTTIGDLIRAQMENQG"
     CDS             241..525
                     /note="ORF_2; himD/ihfB"
                     /codon_start=1
                     /transl_table=11
                     /product="HimD"
                     /protein_id="AAM27583.1"
                     /db_xref="GI:20559808"
                     /translation="MTKSELIERIVTHQGQLSAKDVELAIKTMLEQMSQALATGDRIE
                     IRGFGSFSLHYRAPRVGRNPKTGESVRLDGKFVPHFKPGKELRDRVNEPE"
     CDS             554..895
                     /note="ORF_3; hypothetical orfA"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="AAM27584.1"
                     /db_xref="GI:20559809"
                     /translation="MLWIKRVLLGCGLLFVALFVILLTVENQQTTHFKLLGFYSPEFS
                     IVLYMTLAFVLGGFFGLLIGMPLVARMRVRLGAIRKELAKAQRESDLLQAKLIAYSGG
                     TVNSPLSGESV"
     CDS             1126..2175
                     /note="ORF_4; wzz; similar to chain length determinant
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /gene="wzz"
                     /product="Wzz"
                     /protein_id="AAM27585.1"
                     /db_xref="GI:20559810"
                     /translation="MSDKQSSEAVNYEVDFMELIRELWKSRWLVVLSGFFLGLLAALY
                     AYLSKPVYEARVIVLPPSLSSVAGFNQGRTSDSGLQPFKVQDVYSVFIRNLQSDESLR
                     RFFENIYLPSLTDAERSESREKLFRSFSKQISISLPDRAQPDRYLIVARQGNPELAAE
                     WVKKYLADAADRSLQEMMANAYREIEVKARDVERRIYVLRETAKLRREDRITQLREAL
                     KVADSLGLERPPIINDQMPEQLSAIMSGNLMYMRGSKALKEEILVLEARTSDDPFIPA
                     LRTLQELESLYRGLSIKSEQVAVFRQDGVVEVPDFPVKPKKLLILFGGVMLGGMLGML
                     FVVIRLFYRRNAKLS"
     CDS             2455..3435
                     /note="ORF_5; similar to NAD dependent
                     epimerase/dehydratase f"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="AAM27586.1"
                     /gene="orf2"
                     /db_xref="GI:20559811"
                     /translation="MKKVLVTGADGFIGSHLTELLVGEGYEVKALSQYNSFNYWGWLE
                     DVACLKQIEVLNGDVRDPHYCKKITKDVDVVFHLAALIAIPYSYVAPDSYLETNVKGV
                     LNICQAALENGVQRVVHTSTSEVYGTAQYVPIDEKHPLQPQSPYSASKIAADAMAMSF
                     FNAFDLPVTIARPFNTYGPRQSARAVIPTIIAQIAKGMKQIKLGDVFPTRDFNYVIDT
                     CRGFLELARCEKAIGETVNIGSNYEISVGDTLKLIRELMGSDVEFVTDDQRLRPEKSE
                     VFRLWCDNSKIHELTGFEPTYSIREGLQETINWFVRPENLAKYKADLYNV"
     CDS             3443..4594
                     /note="ORF_6; similar to DegT/DnrJ/EryC1/StrS family"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf3"
                     /protein_id="AAM27587.1"
                     /db_xref="GI:20559812"
                     /translation="MFDALIDFVREQYRTHDFIPLHAPVFSGNEKKYVVETVDSTFVS
                     SVGAFVEKFENNIATYTGSPRAVATVNGTAALHVSLLLAGVKAGDLVITQPLTFVATC
                     NAIAYCGAEPVFIDVDRHTLGLSPLALAAWLDEHARLDNDGVCRTKVGDRILRACLPM
                     HTFGHPVELDALLEVCGRWGLIVIEDAAESLGSLYKGRHTGTFGSLGTLSFNGNKIIT
                     TGGGGMVLAGEELGARAKHITTTAKKPHAFEYVHDEVGYNYRLPNLNAALGCAQLENL
                     ESFVASKRLLASRYKEFFARHSVEFVIEPLGCRSNYWLNAILCENQRQRDSLLEITNK
                     VGVMTRPIWKLMTHLPVYEKYRRGELTNALWLEERVVNLPSSVLPEPFP"
     CDS             4654..5745
                     /note="ORF_7; similar to UDP-N-acetylglucosamine
                     2-epimerase"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf4"
                     /protein_id="AAM27588.1"
                     /db_xref="GI:20559813"
                     /translation="MKDIASHNELQLQTVVSGMHLSPEFGETWRAVESDGFSIDAKVE
                     MLLSSDTDVGVAKSMGVGILGFADALDRLRPDILIILGDRFEALAIAQVALVMKIPIA
                     HLHGGEITEGAYDDAIRHAITKFSYLHFTSTEQYRKRVIQLGESPERVFNVGAIGLDH
                     LLRTSKISREALSESLDFDLSSPYLLVTYHPVTLAEEEPQSTFRALMQALDCFPSYNV
                     IITYPNADNGGRTIIPLVETYARQSAGRVKAIPSLGFKRYLSAVAMASAVVGNSSSGI
                     IEVPTFGIPTVDIGARQKGRLAAESVIHCAADALSIQDALRRALTPEFAESCKKVINP
                     YGAGNTSQRIVHILACSEVNYNKPFYNLS"
     CDS             5749..6834
                     /note="ORF_8; similar to NeuB family"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf5"
                     /protein_id="AAM27589.1"
                     /db_xref="GI:20559814"
                     /translation="MKAPDERAVFVIAEAGVNHNGDRDLAFKLIDVAAQAGVDAVKFQ
                     TFNAKRLASRSAPKANYQKHTTDVTESQLAMLKKLELPKEWHFELQAHAHHNGIEFIS
                     TAFDSDSLAFLAEMQLPFFKVPSGELTNGPLLWAFAKTGKPLILSTGMATLSEVEQGL
                     AIVAHALSCDNEPKDMDEVWRLWSNPSVRMQLQGHVSLLHCTSQYPTPPDEVNLLAMD
                     TLRSFGLAVGYSDHTEGGLVPIAAVARGACIIEKHFTLDRSMPGPDHKASLEPGELAQ
                     MVAQIRMLEVALGSPYKAPQPSEWDTRQAARQQVVAARDIEAGMIITRDDLTTARSGH
                     GLPPTSLWELVGSTSKRAFLAGETLEK"
     CDS             6831..7499
                     /note="ORF_9; similar to Bacterial transferase hexapeptide
                     (four repeats)"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf6"
                     /protein_id="AAM27590.1"
                     /db_xref="GI:20559815"
                     /translation="MRPSMPVSMPLVLMGAGGHAKVLYSLINACGLSLLGVCDPGLAG
                     AGTSHWRGVPVLGGNEVLETLDPDSVRLANGIGQVVGKNVRQRIYEQAREKGFIFPPL
                     VHPSVWLDESVTLSDGSQLMAGAIVQPDVKIGCNSLINTNASLDHDCQIGDHVHVAPG
                     SVLCGGVVVATGAFIGSGATVIQGITIGERSIVGAGTVVVRDVPERSILTGPSVRPRP
                     LAGD"
     CDS             7519..8565
                     /note="ORF_10; similar to Nucleotidyl transferase"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf7"
                     /protein_id="AAM27591.1"
                     /db_xref="GI:20559816"
                     /translation="MKQWEKALITLDSTIEDAITTLDRVAMRIVMIVNDQRQLLGTLT
                     DGDVRRALLKQLPLNTPVGNVMCKTPRTAERDWGRERILSVMEKYSLLQLPIIDEKRK
                     VIGLQTLHDLLNKPRLDNPVFLMAGGFGTRLRPLTHNCPKPLLKVGEKPILEIILERF
                     IGAGFHRFFISTHYMPEMIREHFGDGSRWGVSIRYVHEETPLGTGGALGLLPHHEIDS
                     PLFLMNGDLLTTLNFLNLLEFHTAHGGVATMCVREYEYHVPYGVVQSDGHRISSMVEK
                     PVQKFFINAGIYLLSPGLVKSVKAGTRIDMPTLLEQEIERQQAVNMFPVHEYWLDIGR
                     MEDFVRAQQEFASL"
     CDS             8562..9572
                     /note="ORF_11; similar to Oxidoreductase family,
                     NAD-binding Rossmann fold"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf8"
                     /protein_id="AAM27592.1"
                     /db_xref="GI:20559817"
                     /translation="MTSNECFLIVGSGSIARRHMRNIQSTYPQAKIVCVSASGRELNS
                     NELPSGVSALGSLHDALQVIPTFAIIASPAPLHVEQASLLASSGVSILVEKPLSDSLV
                     RFASQGGASLNGKRILVAYNLRFMPSIRVFRQYIDSGKLGRIHSVSCEVGQYLPDWRP
                     DSDYRKNVSAQRTLGGGALLELSHELDYLQWLFGPVANVYCIARISGALELDAEDTVD
                     ALLVSQKGYVINLHMDFLQRTATRKCKVVGEHASLEWNILDNSVVLYSSLGKKQVLYS
                     DQEYDRNRMYIDELLHFVDVAKGKTSALVTIEQGLETLKLVEALKRSSASGKVISLRD
                     FS"
     CDS             9569..10267
                     /note="ORF_12; similar to Cytidylyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf9"
                     /protein_id="AAM27593.1"
                     /db_xref="GI:20559818"
                     /translation="MTTAYSFIFARGNSKGLPGKNIKILGTKPLLAHSIDVARSVREI
                     SKIFVSTDCKAIADVAQQYGAEVIWRPEELATDNSPEWLAWQHAIKTLRDRGDQFDLF
                     VSLPATSPLRSTEDVQNCIYGIDENVDIVVTATPAARSPYFNMLVRDERGISTTVCSG
                     DTIYRRQDAPMVYDMTTVAYVTRPEYILGNERLFAGVVRSIVVPRERAIDIDDIYDFK
                     MAEMLIMEKESNIC"
     CDS             10261..11019
                     /note="ORF_13; similar to short chain dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf10"
                     /protein_id="AAM27594.1"
                     /db_xref="GI:20559819"
                     /translation="MLNGKRVLISGAGGLLGTRLVERLLSENSIVIAADLDVELLRER
                     LKAIGISEHSSLSLEKLDLNDSEEVMFFFNALPCLDGAVNCAYPRNKQYGRKFFDVEL
                     KDFNENLSLHLGASFLFMQQCAKFFEKHKTPFSLVNISSVYGVAAPKFEIYKDTSMTM
                     PVEYAAIKSALIHLSRYAVSFVGDSNFRSNCVSPGGILDSQPSSFLLSYRDECLGKGM
                     LNVEDVLGSIVFLLSDQSKYMNGQNLIIDDGFTL"
     CDS             11117..12355
                     /note="ORF_14; potential multiple membrane spanning
                     domains."
                     /codon_start=1
                     /transl_table=11
                     /gene="wzy"
                     /product="polymerase"
                     /protein_id="AAM27595.1"
                     /db_xref="GI:20559820"
                     /translation="MVFSFLLFRNKKIICPSNVVFGNYFLYLVFPATLFYILEWLSWD
                     YVLPWGKLNDWASVSQEAILAYLYVFTLFFLFTRFFETLFDRVERSEIIYEYRARPLA
                     IFLCALSLLIGCIYFLQVTGGLDSWVENYSETYLSKKKGYGLLNFFLIMWSNFLAFWL
                     GFYFKTSHRKSWFLVVFVLLVLGFCAYVQGIKSRIFLFGIFFSLPWLASARLSLKQGI
                     VLFLGFMFLFSGAMYVRSNGFYNSPEMLLEYFLTYFNTIFLHDMILHDMQPDYLATMS
                     FPLNKWLTFVGIPSPDYLHDISRWLTSIYFPSQWFKESATQQWPIETELYLNYGAYIF
                     WSIPIFIYSLYMCALYSLRFRGGPVLLFIFMAELFLFLSMFRGSMLQWIYIFHVLFYL
                     MLLVGQRLLFIRIKSRGMVE"
     CDS             12498..13646
                     /note="ORF_15; potential multiple membrane spanning
                     domains."
                     /codon_start=1
                     /transl_table=11
                     /gene="wzx"
                     /product="flippase"
                     /protein_id="AAM27596.1"
                     /db_xref="GI:20559821"
                     /translation="MNAEDVGIYGLVAATIGYGVYIVGFEFYNYSNRELVIAPQSEWL
                     PLIRDQFLLYLLIYVVTLPFIVTVFWGGWLPWPYFSIFVTLLLLEHIAQEFNRILVAA
                     SKQLLASVVLFVRSGIWCLVVILCMWFDPVFRSLQFTFYSWIISCLFACIIAIYQILR
                     LGKLRGSRPVNWTWIRNGIKVALPFLLASLAIRGIYTFDKYFVDSISNLQVLGAYTIF
                     VGMATAVLSFLDAGVFVFYIPRLIRSAKNESTHDFQKVMRELTINTVIVIFFLSVLCC
                     FAGILISTWLSSPVYKENLDMLYWLLFASALYGLSTIPHLGLYAYGRDRPILHSQLCG
                     FCVFILSAYLFSSSWGVSSIAVSMAISFFFIFAWKTSAYFSFVKDANN"
     CDS             13689..14969
                     /note="ORF_16"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="AAM27597.1"
                     /gene="orf13"
                     /db_xref="GI:20559822"
                     /translation="MIEYILATRNEINIDVHLYKLSGLQPRELGYLPRPSKGLGVGKV
                     GVFFFYLLRYFWRYGAAYFFFYLEWLRLRGKVRKNGAFPSLNFDVFGLAFSYRVADLA
                     SSSIKGQSFCWLTVPWISFELGEDRAISLFEFLDKDDLRRAFILSCMAVRKLTILRKT
                     RNWELQGYTAFRWFCVRFALDKLPASYFLIGEHFDRWAVLVDAVVSAKRRNKSVTNSD
                     NGIIMLQHGSLASLGECNSVEETDFPISLPVRLRNVVKLYAFDDASRFIFRRYIFSKL
                     CALRDESVVIYKPRLNLTHFKHARPVNILFVGHPLCESAHVDIFRGLTDEFVVGFYYK
                     PHPVNPCSSKVFKEEWVVIRDKALFPKVDMLISYPSTLVEEYESMGIPGIIHPLNIQP
                     SSVGEVCDSASRLLEALGCERKVDRQGQEFLRKK"
     CDS             15005..16108
                     /note="ORF_17"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf14"
                     /protein_id="AAM27598.1"
                     /db_xref="GI:20559823"
                     /translation="MDTSDPHIHFDQQGVCEYCQNFDEAIKPNWHTDKHGEAELKRLA
                     EVIKRDGKGRDFDCIIGLSGGLDSSYVSYVAKEKMGLRPLLFHVDAGWNTDQAVGNIE
                     KLVDGLGLDLYTEVINWEEMKDLQVAFLKSQISDQDLPQDAAFFSALYKFARAHKIKY
                     VLTGGNFSTECCREPEEWGGYPGIDKRLFKDIHKRFGTRTLKTFPIVDILAYKIYYRY
                     VLGMQVIRPLNLLPYVKKDAEETLQRLYGWQSFQHKHHESRFTRFYEDYWLPRKFGYE
                     KRRAHFSSLIMTGQMTREEALERISKPEMDENFLRSEFEYVANKLDLSIEDLQFIFDG
                     ENKTFHDYKNKHFMIGLGARIMNTLGLERRLFR"
     CDS             16105..16719
                     /note="ORF_18; similar to Glutamine amidotransferase
                     class-I"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="AAM27599.1"
                     /gene="orf15"
                     /db_xref="GI:20559824"
                     /translation="MITIIDYGIGNIQAFVNVYKRLHIPAQVARVNSDLKNVEKLVLP
                     GVGSFDHAMLRFTESGMREAVEFLVKDKGIPVLGICVGMQMLADRSDEGKLPGLGWIP
                     GHVRSFRSVTGLQNIAMPHMGWNDVVSVGNNPLFNGLEQGARFYFLHSFYFESLYLEH
                     VAAGTFYGHDFNSAVSRDNIFGVQFHPEKSHHFGVKLLKNFAEL"
     CDS             16721..17503
                     /note="ORF_19; similar to Histidine biosynthesis protein"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf16"
                     /protein_id="AAM27600.1"
                     /db_xref="GI:20559825"
                     /translation="MLKPRIIPCLLMQDGGLVKTVRFKDPRYIGDPINAVKIFNEKEA
                     DELIILDIDATSQGREPDYKKIANLAAECRMPLCYGGGIRKPEQARLIISLGVEKVAI
                     SAAAIEDANLISKVAEEIGRQSVVVVLDHKQRLLSKQHDVWTHNGTHNTKRNVIDVAK
                     QMEDAGAGEIVLNSIDNDGRLCGYEIALAVRLREAVNVPVTILGGAGSLKDMGSLIAA
                     CGVVGAAAGSLFVFKGSYRAVLINYPSFQQKTDVIFSVLNSR"
     CDS             17537..18571
                     /note="ORF_20; similar to Polysaccharide biosynthesis
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /gene="gtr1"
                     /product="glycosyltransferase"
                     /protein_id="AAM27601.1"
                     /db_xref="GI:20559826"
                     /translation="MFSGKRLLISGGTGSFGNAVLKRFLDTDIAEIRIFSRDEKKQDD
                     MRKHYANSKLKFYVGDVRDYQSVLTATRGVDYIFHAAALKQVPSCEFHPMEAVKTNVI
                     GTENLLEAAIQNDVRRIVCLSTDKAVYPINAMGISKAMMEKVMVAKSRNLETTSTVIC
                     GTRYGNVMASRGSVIPLFIEQMRSGKPLTITDPSMTRFMMTLSDAVDLVLYAFEHGNN
                     GDLFVQKAPAATIEVLAKALTSLLGKQDYPINVIGTRHGEKLYEALLSREEMACAEDM
                     GDYYRVPPDLRDLNYSKFVEQGEEKISHTEDYNSHNTERLDVKGMQELLLKLDFVRAI
                     QRGEQANPEE"
     CDS             18575..19696
                     /note="ORF_21; similar to NAD dependent
                     epimerase/dehydratase fam"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf18"
                     /protein_id="AAM27602.1"
                     /db_xref="GI:20559827"
                     /translation="MRVLITGANGFVGKNLTAHLAERGDVEVVTFTRESNLQSLPEML
                     GSIDFVFHLAGANRPENPEDFKSINSDLTKTLCDAIRATGRSIPLIYTSSTQAELQNS
                     YGLSKRDAEEYIRRLNSETGSPVYIFRLPNVFGKWSRPNYNSAVATFCYNISRDLPIQ
                     VNDSSAQVTLVYIDDVIQKFLAVLDAPTATHDVSVEPQYKITVGDLAKQIHAFRDSRK
                     SLVTEQVGVGLVRALYSTYLSFLPVNRFSYDLPMYGDARGTFVEMLKTPDAGQFSFFT
                     AHPGVTRGGHYHHSKTEKFLVIKGTARFKFRNISTGAFHELCTRGEKAEVVETVPGWT
                     HDITNIGSEEMIVMLWANEIFDRERPDTYACPVGEVSDL"
     CDS             19707..20837
                     /note="ORF_22; similar to UDP-N-acetylglucosamine
                     2-epimerase"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="AAM27603.1"
                     /gene="orf19"
                     /db_xref="GI:20559828"
                     /translation="MKKLKVVTVVGTRPEIIRLSRVMAKLDEYCDHVLVHTGQNYDYE
                     LNEIFFQDLGIRKPDHFLNAAGVSGAETIGNVIIAVDRVLSVEQPDALLVLGDTNSCM
                     AVLPAKRRKIPTFHMEAGNRCFDMRVPEEINRRIVDHTADINLTYSTIARDYLLREGL
                     PPDMVIKTGSPMFEVLNYYRDGIESSDVLARLGLEENKFFVVSAHREENIDSESNFLS
                     LVETLNEISEKYEFPVIVSTHPRTMKRVEAMGVRFHANVRLLKPLGFKDYNKLQLSAK
                     AVLSDSGTINEESSILNFPALNIRQAHERPEGMEEAAVMMVGLGRERVLQGLEILESQ
                     SRGASRLLHLVHDYSCDNVSEKVVRILVSYRDYVMRTVWKKY"
     CDS             20845..22098
                     /note="ORF_23; similar to Glycosyl transferases group 1"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="AAM27604.1"
                     /gene="gtr2"
                     /product="glycosyltransferase"
                     /db_xref="GI:20559829"
                     /translation="MDKTKLKVLVVTQYFWPENMRINDLVADFVGRGHEVTVLTGCPN
                     YPEGRVFSDFKENPASYSCYLGASVIRVPMLPRGLHSIQLALNYLSFFMSASFFGAFR
                     LRRKKFDVVFVYAVSPIMAVIPAIVIGRLKRAPVFVWVLDLWPETLRAVGVLKSDRAL
                     SIVGRVVSWIYNRTDYILVQSKAFMDNVAKYCTKTIPEDRVIYFPSWAEDDFSNNESA
                     SSTLLERDDSVFTLLFAGNVGEAQDFPSILDAAERLRQDVPMRWVIVGDGRASAWLKA
                     EVAARGLDNVLLLGRHPLEEMPPLFALADALFVSLKTNEVFEKTIPGKVQAYLASGKP
                     VIAMIDGEASRVISEAGAGYACASGDVEALVDIIRRAAALTGEQREGLGRAGREYYEC
                     NFSKRTLLSRLEGLFIDARLRRDEK"
     CDS             22095..23051
                     /note="ORF_24; similar to NAD dependent
                     epimerase/dehydratase family"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf21"
                     /protein_id="AAM27605.1"
                     /db_xref="GI:20559830"
                     /translation="MNKVLLTGASGFVGKALAGELLRQGYALNMAFRQTPSKVLEGAV
                     AIPVGNIEGDTLWSDALAGVDTVIHSAARVHVMNDHALDPLAEFRKVNVEGTLNLARQ
                     AAAAGVKRFVFVSSIKVNGESTTAGSPFKPDDVPAPSDPYGISKLEAEIGLRQVCEEA
                     GMEYAIVRPVLVYGPGVKANFLNMMKWLDKGIPLPLGAIKNRRSLVSLTNLMDMLITV
                     ASHPAAANQVFLVSDGEDLSTTGLLRRMAAAMGKRANLLPVPESLLKTAALLLGKKSV
                     GQRLCGSLQVDISKNKQLLDWNPPLSVDQGLQRVAEYYLEYR"
     CDS             23053..24072
                     /note="ORF_25; similar to Glycosyl transferase group 4;
                     potential multiple membrane spanning domains."
                     /codon_start=1
                     /transl_table=11
                     /gene="gtr3"
                     /product="glycosyltransferase"
                     /protein_id="AAM27606.1"
                     /db_xref="GI:20559831"
                     /translation="MSIWWILFPVVLVSAGLTGVLRFYAISKKVMDIPNARSSHTVPT
                     PRGGGVAIVLTFLLVVFFLPLFSILEWRQALLFLLGGGGVALLGFLDDHGHVAARWRL
                     LGHFMAALVSLFLLTGVPPFKLLGYQWDLGWVGVVLFAFYLVWLLNLYNFMDGIDGLA
                     SLEAIFVCVGGALVYWMNDKAAFSLPPLLLAFAVLGFLFWNFPPAKIFMGDAGSGFLG
                     LTLGVLSIQAMWVEPEFFWAWLILLGVFIVDATYTLARRLLRGDKVYEAHRSHAYQYA
                     SRHFGKHAPVTLGVTVLNLVWLLPLALWVASGHLEPVLGIAIAYTPLVFLAVKFKAGK
                     LESVG"
     CDS             24107..>24949
                     /note="ORF_26; similar to N terminal coding region of
                     Polysaccharide biosynthesis protein WpbM"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="AAM27607.1"
                     /gene="wbpM"
                     /db_xref="GI:20559832"
                     /translation="MLDRFRVKLLSMPRRWKRLLQVATDILLVWLSLWLAFVVRLGTD
                     DMIDIFGEHAWLFIAAPLIAIPLFIRFGMYRAVMRYLGNDALIAIAKAVTISALVLSL
                     VVYWYRGAPAPVPRSLVFNYWWLSMLLIGGLRLAMRQYFMGDWYSAVQSVPFLNRQDG
                     LPRVAIYGAGAAGNQLVAALRLGRTMRPVAFIDDDKQIANRVIAGLRVYTAKHIRQMI
                     DETGAQEVLLAIPSATRARRREILESLEPFPLHVRSMPGFMDLASGRVKVDDLQEVDI
                     ADLLG"
BASE COUNT     6022 a   5034 c   6497 g   7396 t
ORIGIN
        1 acgagaagga cgcaatgaaa gaactgcgta agcaggaagt agaaagcgct ggtccgacca
       61 ccatcggtga cctgatccgt gctcagatgg agaatcaggg ctaagtctct gatccatcat
      121 gaaaaagggc ggcctaggcc gccctttttc gttttcgcct tcttggacct gttcaaagac
      181 tgatcagcat gctaaaagag acctgagctg atctagccgc ttgaaaaaga agggaaaacc
      241 atgaccaagt cggagttgat cgaacggatc gttacccatc aggggcaact gtccgcgaag
      301 gatgtcgagt tggcaatcaa gaccatgctg gagcagatgt cccaggccct ggcgaccggg
      361 gaccggatcg agatccgcgg cttcggcagc ttttccttgc actaccgcgc accgcgcgtc
      421 ggtcgcaatc ccaagaccgg ggagtcggta cgcctcgacg gcaagttcgt gccgcacttc
      481 aagccgggca aggagttgcg ggatcgggtc aacgagccgg agtgatcttc aaccatatca
      541 cattggagtc ttaatgcttt ggatcaagcg tgtattacta gggtgcgggc ttttattcgt
      601 cgctcttttt gttattttgc tgacggtcga gaatcagcag actacacatt tcaaactgct
      661 tggtttttac agtcctgaat tctcgattgt actttatatg accttggcct ttgttttagg
      721 tgggtttttt ggtctcttga tcggcatgcc tcttgttgcg cggatgagag ttcgccttgg
      781 ggcaataaga aaagagctag ccaaggctca aagggagagt gaccttctcc aggctaagct
      841 catagcttat agtggaggta cggtcaactc gcctttatcg ggcgaaagtg tataaaaagt
      901 gtataaacag cttcatattc tccgccggaa ctaaacttta caatggaggt ctaaggccaa
      961 gcgatttttt ttgaaaaccg tttggacacc acatggtaca gtttgtgaat gtaaatagag
     1021 gtttaacttt acctggcgag gcttggttca ttaatctgga tgacatataa gaattttttc
     1081 ggtttctttc taagagttac ccagaatatt gatatggaat aaaaaatgtc cgataagcag
     1141 agtagtgaag cggttaatta tgaagtggat tttatggagt tgatacgtga gctctggaaa
     1201 agccggtggc ttgttgttct aagtgggttc tttttagggc ttttagcggc gctctatgcc
     1261 tatttaagta agcctgtcta tgaggctcga gttattgtac tgcctccttc gttaagcagc
     1321 gttgcaggct tcaaccaggg gcgaactagt gattctggat tgcagccttt caaggttcaa
     1381 gacgtttatt cggtttttat tcggaatctt cagtctgatg aatcgcttcg ccgatttttt
     1441 gagaatattt atttgccgtc tctaactgat gcagaacggt cagagtcgcg cgagaaactt
     1501 tttcgctcct tcagtaagca gataagcatt agtctgccgg atagagcgca gcctgatcga
     1561 tatttaatag tagctaggca aggtaatcca gagttagctg ctgagtgggt aaaaaaatat
     1621 cttgccgacg cagctgatcg gtctctgcag gagatgatgg ctaatgcata ccgtgagatt
     1681 gaggttaaag ctagggatgt tgaacgacgc atttatgttt tgcgtgaaac tgcaaaactg
     1741 cgtcgagagg accgcattac tcaacttcgt gaagctttaa aggtggccga ctcgttgggt
     1801 ttggaaagac ctccaataat taatgaccag atgcctgagc agctctcggc aataatgagc
     1861 ggtaatctta tgtatatgcg aggaagtaaa gcattgaaag aggaaatcct ggttctggaa
     1921 gcgcgaactt cggatgatcc ttttattcca gctttaagga ctttgcagga gttggagtcg
     1981 ctatacaggg ggctgagtat caagtctgag caggtcgcag tttttcgtca ggatggtgta
     2041 gtggaagtac ctgatttccc cgtgaagcca aaaaagctat tgatcttatt tggcggggtg
     2101 atgctgggag gaatgcttgg tatgcttttt gttgtaattc gattgtttta taggcgaaat
     2161 gctaagcttt cctaatatcg ttgtcggtaa gctaactgag tttttgtttt tttgttcggg
     2221 gggaggagct tgaaatgtat ggcgataatg tctcgagggt aatatggttg ttgagcacca
     2281 atgaaaggtg tgtgcggtta cgaatgttgt gaagttgaag gttaagatgc gaagggggca
     2341 tgtcttagca tcggaaggcc atttgagatt ttcttgtgct atcatagtaa ggtaataatt
     2401 tcggttcatt cgcttgtgca gaagcgttcg ttatcgattg tttaggaagg aaatatgaaa
     2461 aaagttttgg ttactggggc ggatgggttt attggttcac atctcacgga gttgttggtt
     2521 ggtgaaggct atgaagtaaa agctttgtct caatataatt cttttaacta ttggggttgg
     2581 cttgaagatg ttgcttgtct taagcaaatt gaagttttaa atggagatgt acgcgatcct
     2641 cattattgca aaaaaattac aaaagatgtt gatgtggttt ttcatcttgc tgctcttatt
     2701 gctattccat attcttatgt ggctccggat agttatttgg agaccaacgt taaaggggtt
     2761 ctaaatattt gccaagctgc cttggagaat ggtgttcagc gggttgttca cacttcaact
     2821 agcgaagttt atggtactgc tcaatatgtg ccaattgatg agaagcaccc gctccagccg
     2881 caatctccct acagtgcgtc aaagattgcg gcagatgcta tggcaatgag cttttttaat
     2941 gcctttgatc ttccagtcac tattgctcgt ccatttaata cttatggacc taggcagtca
     3001 gctagagctg ttattcccac tataattgct cagatcgcaa aaggtatgaa gcagataaag
     3061 ctaggagatg tgtttccaac ccgtgatttt aactatgtga tcgatacttg cagagggttt
     3121 ctcgaattgg cgcgttgcga gaaagccatc ggtgagactg taaatattgg gtctaattac
     3181 gaaatttctg ttggcgatac attgaaactc attcgggagt tgatggggag cgatgtggag
     3241 tttgttactg acgaccagcg cttgaggcca gagaaatcag aagtctttcg tctttggtgc
     3301 gataactcca aaattcatga gttgacaggt ttcgagccta cctactcgat tcgagagggt
     3361 ctgcaagaaa caattaactg gtttgttcgc ccagaaaatt tggcgaagta taaggccgac
     3421 ctctacaacg tctgaggctc tcatgtttga tgcgttaatt gattttgttc gtgagcaata
     3481 ccgcactcat gatttcattc ctttgcatgc tccggttttt tctggaaatg aaaagaagta
     3541 cgttgtcgaa actgtagatt cgacttttgt gtcgagcgta ggcgctttcg ttgaaaagtt
     3601 cgaaaataat atagcaacct atactgggtc gccgagagca gtagctacgg ttaacggtac
     3661 ggcagcttta catgtttctt tattgcttgc gggggttaaa gccggtgatt tggttatcac
     3721 tcagcccctt acatttgtcg ctacatgcaa tgcgattgca tattgcggcg cagagcctgt
     3781 gttcattgat gtagaccgac ataccctggg tctttctccg ctagcgctcg cagcttggct
     3841 ggacgagcat gcccgtttgg ataatgatgg agtatgtagg accaaggttg gagatcgtat
     3901 attacgtgct tgtttgccaa tgcatacttt cggccacccg gttgagttgg acgccttgct
     3961 tgaggtttgt gggcgttggg ggttgattgt gattgaagat gctgccgaat cactcggaag
     4021 tctctacaaa ggtcgtcata ctggtacttt cggttcactc ggcacattaa gctttaatgg
     4081 caataaaatc atcaccactg gtggtggggg catggtcctg gcgggggaag agttaggagc
     4141 tagagccaaa catatcacta caactgccaa aaaacctcat gcatttgaat atgtacatga
     4201 tgaagttggc tacaattatc gccttcctaa cctgaatgct gctctaggat gtgcgcagtt
     4261 agaaaattta gagtcgtttg tagcatccaa acgtttgctg gcatcccgtt ataaagaatt
     4321 cttcgctagg cactccgttg aatttgtcat agaacctttg ggatgtcgct ccaattactg
     4381 gttaaatgcg attctttgcg agaatcagag gcagagggat tctctcttgg agataactaa
     4441 taaggttgga gttatgactc gacctatttg gaaactcatg acgcatcttc ccgtatatga
     4501 gaagtaccga cggggtgagt tgacgaatgc tttatggcta gaagagcggg tggtaaacct
     4561 tccgagtagc gtattgccgg agccgtttcc ttgattcgta aagtggcggt ttttacagga
     4621 agccgggctg agtatggtct gctgtattgg ttgatgaagg acatcgcatc ccacaatgag
     4681 ttgcagttac agactgtcgt tagtggaatg catctctctc ccgagtttgg tgagacttgg
     4741 agagcagttg aaagtgatgg tttttctatt gatgctaaag tagaaatgtt actttcttct
     4801 gatactgacg ttggcgtggc taagtctatg ggtgtgggaa tcctaggttt tgctgatgcg
     4861 cttgatcgcc tccgtccgga tattctcatt attttaggcg atcgtttcga agcgcttgcc
     4921 attgcccagg tggccctagt aatgaagatt cccatcgctc atttgcatgg tggggaaatc
     4981 acagagggtg cttatgatga tgctatccgt catgccatca cgaagttttc ttatctacat
     5041 tttacgtcta ctgagcaata tcgcaagcga gtgatccagt taggagaatc gcctgagaga
     5101 gttttcaatg tcggagcaat agggctggat catcttctcc gaacatcaaa aataagccgc
     5161 gaagccttat ccgaaagtct cgattttgat ttgtcctctc cgtatctact ggtcacttat
     5221 catccggtaa cgcttgctga ggaagagccg caaagcacct ttcgagcttt aatgcaagcc
     5281 ttggattgtt ttccaagtta taatgttatt atcacttatc caaatgctga taatggcggg
     5341 aggacgatta ttccattagt ggaaacctat gcgcgccaat cggcgggacg cgtcaaagcc
     5401 attccatcgt taggtttcaa gcgatacctg agtgctgtag ccatggctag tgcggtggtt
     5461 ggcaactctt ctagcggtat tattgaggtg ccgacgtttg gtataccgac tgttgatatc
     5521 ggagcacgtc agaaaggccg attggcagct gaatcggtga ttcactgtgc agctgatgcg
     5581 ttatcgatac aggatgctct gcggcgtgct ttgacgcctg agtttgcaga gagctgtaaa
     5641 aaagttatca atccttatgg agcaggtaat acttctcagc gaattgtcca tatcctcgcc
     5701 tgctctgagg tgaactataa taagcccttc tataacttga gctaaattat gaaagcgcca
     5761 gatgaaagag cggttttcgt tattgcggaa gctggggtca atcacaatgg tgatcgggat
     5821 cttgctttca aactaattga tgtagcggcg caagcagggg tcgatgcagt aaaattccag
     5881 acttttaatg ccaaacggct ggcatctcgc tctgcaccaa aggcaaatta ccaaaagcat
     5941 actactgatg taactgaaag tcagttagca atgttgaaga agcttgagct accaaaagag
     6001 tggcatttcg agctgcaggc gcatgcccac cataacggta ttgaatttat ttctaccgcg
     6061 tttgactcgg acagtctagc ctttttagcc gaaatgcagt tgcctttttt taaggtgccg
     6121 tcgggagaac ttactaatgg accactccta tgggcattcg cgaaaacagg taaacctctg
     6181 attctatcta ctggtatggc cacattgagt gaagttgagc agggcctagc catcgtggcc
     6241 catgctttgt catgcgataa tgagcctaaa gatatggacg aggtgtggag actttggagt
     6301 aatccttctg ttcgaatgca attacaagga catgtgtctt tactgcattg cacctcccaa
     6361 tatccaaccc ctcctgacga ggtgaacctt ttggcaatgg acacgctgag aagctttggt
     6421 cttgccgtcg gatattcaga ccacactgag ggggggctgg tgccgattgc agcggttgcc
     6481 aggggggcgt gcatcatcga aaagcacttt actctagatc gttcaatgcc ggggcctgac
     6541 cataaagctt cgctggaacc cggcgagttg gcccaaatgg ttgctcagat tcgcatgctt
     6601 gaggttgcgt tgggaagtcc ctacaaagca ccgcaaccta gcgagtggga tacacgtcaa
     6661 gctgcacggc agcaggtggt tgcggcgcgt gacatcgaag cgggtatgat tattactcgg
     6721 gatgacctga caaccgcgcg tagcgggcat ggtttgccac cgacctctct ttgggaactg
     6781 gttggcagca ccagcaagcg tgcctttctg gcaggggaaa cactggaaaa atgaggcctt
     6841 caatgcccgt aagtatgccg cttgtcctga tgggggcagg agggcatgcg aaggtattgt
     6901 attcgttgat taatgcgtgt ggactatcct tactgggcgt ttgcgatcca ggcctcgctg
     6961 gagcggggac aagccattgg cgaggtgtgc cagtacttgg aggtaacgag gtgctcgaaa
     7021 cgctcgatcc tgactccgta agactagcta atgggatcgg acaggtggtt ggcaaaaacg
     7081 tacgccagcg tatttatgag caagcccgcg agaaggggtt catatttcca cctctggtgc
     7141 atccttccgt ttggcttgat gaatcagtga cgctgtccga tggttcacaa ctgatggcgg
     7201 gagccatagt tcaaccagat gtcaaaattg gctgtaattc tctgattaac actaacgcga
     7261 gcttggatca tgactgtcag attggtgatc acgtccatgt cgcacctgga tcagtgctat
     7321 gtggaggggt agttgtcgct actggggctt tcatcgggag tggagctacg gtgattcagg
     7381 gaattactat cggtgagcgt tcaattgttg gggccggtac ggtagttgtc agagatgtgc
     7441 cggaaaggag catcttgacc ggaccttcag tgcggccgag gccgttggca ggcgattgat
     7501 ttttagagaa ggaatgcaat gaagcagtgg gaaaaagcgc tcattactct ggatagcacg
     7561 atagaggacg cgatcactac tttggatcga gttgcgatgc gaattgtcat gatcgtgaac
     7621 gaccagcgac agttgcttgg aacccttacg gatggagatg taagaagagc tctgcttaag
     7681 caactaccgc tgaatacgcc agtagggaat gtaatgtgca aaacccctag aacggccgag
     7741 cgggattggg ggcgagagcg tatcctgtcc gtgatggaga agtactctct tctccagtta
     7801 ccgattatcg acgagaagcg taaggtaatt ggtttacaaa ctttgcatga cttgctgaac
     7861 aagcctcgtt tggataaccc ggtttttcta atggcgggag gctttggtac acgtctccgt
     7921 ccactaactc ataattgccc gaagcctctt ttgaaggtgg gtgaaaaacc aattctcgaa
     7981 ataatattag agcgtttcat tggagctggc ttccatcgtt tcttcatttc tacccattat
     8041 atgccagaaa tgattcgtga gcatttcggc gatggaagtc ggtggggtgt cagtatccgc
     8101 tatgtacatg aagaaactcc acttgggaca ggtggggcat tgggtttact accccatcat
     8161 gagatagact ctccgttatt tctcatgaat ggtgacttgt taacaacctt gaatttcttg
     8221 aatcttctcg agttccatac tgcgcacggt ggtgtggcaa ctatgtgtgt gcgtgagtac
     8281 gagtatcatg tgccttatgg cgtagtgcaa agtgatgggc accgcataag ctcaatggtt
     8341 gagaaacctg tgcaaaaatt ttttatcaat gctggaattt atctactttc accaggtctc
     8401 gtaaaaagtg ttaaggctgg cacccggatt gatatgccta ctttattaga acaggaaatt
     8461 gagcgacagc aggcagtaaa catgtttccg gtccatgagt attggttaga tatcgggcgc
     8521 atggaagact ttgtgcgggc acaacaagag ttcgcatctt tatgacaagc aacgagtgtt
     8581 ttctgatagt tggcagcgga agcatagcac gccgacatat gagaaatata cagtctactt
     8641 atccgcaggc caagatagta tgtgtctctg cctcaggtag agagttgaac tcaaatgaat
     8701 tgccttcagg tgtatcagct cttggttctt tgcatgacgc tttgcaggta atccccactt
     8761 ttgccattat tgcttctcca gctcctttac atgtagagca ggcgagtctt ttggcttcga
     8821 gtggtgtctc gattttagtt gaaaaaccat taagtgattc attggtacgc tttgcctctc
     8881 agggtggagc ttcgctgaac ggaaaacgta ttcttgttgc atataatctt cgctttatgc
     8941 cttcaataag agtattcagg cagtatattg atagtgggaa gctagggcga attcattctg
     9001 taagttgtga agttggtcaa tatcttcccg actggagacc agatagtgac tatcgaaaaa
     9061 atgtttctgc acaacgcacc ttaggcggtg gtgctctact tgagttaagt cacgaactag
     9121 actaccttca atggctcttt ggacccgttg ccaatgtcta ttgcatagca cgaatatctg
     9181 gtgcattaga gttggacgcg gaagatactg ttgatgcctt gctcgtatcc caaaagggct
     9241 atgtcatcaa tctacatatg gattttctgc agcgaactgc gacacgtaaa tgcaaagtgg
     9301 ttggtgagca tgcttctctg gaatggaata ttttagataa cagtgttgtt ttgtacagtt
     9361 cattgggtaa aaaacaagta ctttacagtg accaggaata tgatcggaat agaatgtata
     9421 tagatgaact gcttcatttt gtcgacgttg cgaaaggaaa aacttcggca ctggtaacga
     9481 tagaacaagg acttgagaca ttaaagttgg ttgaggcgct gaagcggtct tcagcaagcg
     9541 gaaaggtcat ttctcttagg gatttctcat gacgacagct tattctttca tctttgcgcg
     9601 tgggaattcc aaaggacttc caggaaaaaa tataaagatt ctgggaacaa aacctctgct
     9661 cgcacactct atcgatgtcg ctaggtctgt tcgagaaata agtaaaatat ttgtctcaac
     9721 tgattgtaag gctattgccg acgtagctca gcaatatggg gcggaagtca tctggcgtcc
     9781 tgaagagtta gcaactgata actctccgga atggcttgca tggcaacacg ctataaaaac
     9841 cttgcgagac aggggagatc aatttgattt atttgttagc ctgcccgcga ccagcccatt
     9901 acgtagtact gaagatgtcc aaaactgtat ttacggcata gacgaaaatg ttgacatagt
     9961 cgtcactgct acaccagcgg ctcgaagtcc ttatttcaat atgctggtgc gcgatgagcg
    10021 aggcataagt acgactgttt gttctgggga taccatttat cgtcggcagg atgctccaat
    10081 ggtatatgac atgactacag tagcatacgt tactcggccg gaatacatat taggaaatga
    10141 gaggcttttc gcgggagttg ttaggtcaat tgttgttcct cgagagcgtg ccatagatat
    10201 tgatgacatt tatgatttta aaatggccga gatgttgatt atggaaaaag agtctaatat
    10261 atgttgaacg gtaagagagt gttgatttct ggcgccggag ggctgctcgg tactcgtttg
    10321 gtagaacgat tactatcgga gaactccata gttattgctg ctgatttaga tgttgaatta
    10381 cttcgtgagc gtctgaaggc catcggtatt tcagaacatt ccagtttatc tctggaaaag
    10441 ttggatttaa atgattctga agaggttatg ttttttttta acgctctacc ttgtttggat
    10501 ggagcagtaa attgtgctta tcccaggaac aaacaatatg ggcgaaagtt ttttgacgtt
    10561 gagctaaagg attttaatga aaatctttcc ctccatctgg gggcttcatt cttatttatg
    10621 caacaatgcg ctaaattttt tgagaaacac aagacgccat tctctcttgt aaatatatcc
    10681 tcagtttatg gagtagcggc tccgaaattc gagatatata aagatacttc aatgaccatg
    10741 ccggtagaat acgcagctat aaaatcggcg cttattcatc ttagcagata tgcagtatct
    10801 tttgtcggtg atagtaactt tcggtctaat tgcgttagcc ctggcgggat attagacagc
    10861 cagcctagct ccttcttatt aagttatcgt gatgagtgct tgggtaaggg gatgttgaat
    10921 gtagaagatg tgcttggaag tatagttttt ttgctttctg accagtcaaa atatatgaac
    10981 ggacagaatt tgattataga tgatgggttc actttatgaa gtgtagattt atcattaagc
    11041 taatggctag ggggcgacgt cctattgtgc aagacatggc gtacaataaa tgactctatt
    11101 cttttcctct gcttttatgg ttttttcttt tctgctcttc agaaataaga aaattatatg
    11161 cccgtctaat gtggtttttg ggaactactt cctatatttg gtttttccag ctacgctttt
    11221 ttatatactc gagtggctgt cttgggatta tgtcttacca tgggggaagc tcaatgattg
    11281 ggcatctgtc tcgcaggaag ccatcctagc ttatctatac gtatttacac tctttttcct
    11341 ttttacacga ttttttgaaa cgctttttga tcgagttgaa agatcggaaa ttatatatga
    11401 gtatcgtgcc aggcctttag cgatattcct ttgtgcacta tctcttctta ttggatgtat
    11461 ttattttctt caggtgacgg gagggttgga ttcatgggta gaaaattata gtgaaaccta
    11521 tctttctaag aagaaaggat acggtttgct taatttcttt ttaataatgt ggtcaaattt
    11581 tctagcgttt tggttgggtt tctattttaa aacttctcat cgaaagagtt ggttcttggt
    11641 tgttttcgta cttttagttt tgggtttttg tgcttatgtc caaggtataa aaagtcgaat
    11701 atttctattt ggtatatttt ttagtttacc ttggctagca agcgctcgtt tgagtctgaa
    11761 acaaggtata gtattgtttc tagggtttat gtttcttttt tctggtgcga tgtatgttcg
    11821 ctccaatggc ttctataact caccagagat gctgttagag tattttttaa cttactttaa
    11881 taccatattt ttacatgaca tgattctgca tgacatgcaa ccagactatt tagcgactat
    11941 gtcctttccg cttaacaaat ggttaacttt tgttgggata ccttctcctg actatttgca
    12001 tgatataagc cgttggctta cttctattta ttttccttct caatggttta aggaatctgc
    12061 tactcaacag tggccgatag agactgaact ctatttaaac tatggggcat atatattctg
    12121 gagtatacct atttttatat actccctcta tatgtgtgct ctttattctc taagattcag
    12181 agggggccct gttctgctct ttatctttat ggccgagctt tttttattct tgagcatgtt
    12241 tagaggaagc atgttgcaat ggatctatat tttccacgtg cttttctatc ttatgctttt
    12301 ggtagggcag cgattgttat tcattcgtat taaaagccga ggcatggttg aatgagcagc
    12361 tataggaaaa ataattggtt aaatagacca ggggctcgtt ttttggggca gttgctgtga
    12421 gccgaatttt gaatatcggt ttgcgtggtc taactctatt aaataaattt cttttagtct
    12481 ttttcctggc acatttcatg aatgccgagg atgttggcat ttatggtctt gtggctgcga
    12541 ctattggtta tggagtgtat atagtcggat ttgaattcta taattactct aatcgtgagt
    12601 tagtcatcgc tccacagagt gaatggttac ccttgatacg agatcaattt ctcctatatc
    12661 tcctaatata tgtagtgact ttgcctttta ttgttacagt cttttggggt ggatggcttc
    12721 cttggccgta tttttcaatt tttgtgactc ttttgttact tgaacatatt gcccaagagt
    12781 tcaatagaat attggttgct gcttcgaagc aattattggc aagcgtggtt ctttttgttc
    12841 gtagcggaat ctggtgctta gtagttattc tatgtatgtg gttcgatcca gtttttcgat
    12901 cgctacagtt cactttctat agctggatta tatcttgctt gttcgcatgt attatagcga
    12961 tttatcaaat tcttcgctta ggtaaattgc gtggcagccg cccagtaaat tggacttgga
    13021 tacgaaacgg gattaaagtg gctttaccat ttttgctcgc tagcttagcc atacggggga
    13081 tctatacatt cgataaatat tttgtggata gtatttcaaa tctacaagtg ttaggtgcat
    13141 atacgatctt tgtaggtatg gctaccgctg tcctatcctt tttggatgca ggagtttttg
    13201 ttttctatat tcctcggcta ataaggtccg ctaagaatga atcgacgcat gactttcaga
    13261 aagtgatgcg tgagttaact attaatactg tgattgtaat atttttcctt tctgttctct
    13321 gttgtttcgc tggaatcctt attagtactt ggctttcttc acctgtttat aaagaaaact
    13381 tagatatgtt gtactggcta cttttcgcca gtgctcttta tgggctcagc acgatacctc
    13441 atctaggttt gtatgcttat ggtcgagata gaccaatatt acattcccaa ttatgtgggt
    13501 tttgtgtctt catactctct gcctacttat tttcttcctc ttggggagta agctctattg
    13561 cagtctcaat ggctatttca ttttttttta tctttgcttg gaaaacatct gcatattttt
    13621 cttttgttaa ggatgcaaat aattaattta attttgaggt tattgtgaat aataatctgc
    13681 gaagaattat gattgaatac atcttggcga cgagaaatga aattaatata gatgtacatc
    13741 tttataagtt aagtggttta caaccgcgcg aacttggcta tcttccccgc ccaagcaaag
    13801 gtctaggagt tggtaaagta ggagtattct ttttctactt gttgcgttac ttttggcgct
    13861 atggagcggc ttattttttc ttttatcttg aatggctgcg cctgcgtggt aaagttagaa
    13921 aaaatggagc cttcccatct ttgaattttg atgttttcgg attagcgttt tcttataggg
    13981 tagcagatct agcatcttca agcataaagg ggcagagttt ctgttggctg accgttcctt
    14041 ggattagttt tgagttggga gaggatagag cgataagcct ttttgagttt cttgataagg
    14101 atgacttgcg tcgagctttc atcttgtctt gtatggcggt gcgtaagtta actattttac
    14161 gaaagacaag aaattgggag cttcagggat atactgcatt ccgttggttt tgtgtacgtt
    14221 ttgctttaga taaattgccg gcaagctatt ttctaattgg agagcacttc gatcgctggg
    14281 ctgttcttgt tgatgctgtg gtttcagcga agaggcgaaa taaatcggta actaattcgg
    14341 ataatggcat tattatgctg caacatggtt cattggcttc tctgggcgaa tgtaactctg
    14401 ttgaggaaac ggactttcca ataagtttac ctgttcgcct acggaatgtt gtaaagctat
    14461 acgcatttga tgatgcttca agatttatct ttcgtagata tatcttttca aagctttgtg
    14521 cgctcaggga tgaaagcgta gttatatata aacctcggct aaacttgaca cacttcaagc
    14581 atgccagacc tgtgaatatt ttatttgtag ggcatccttt gtgtgaaagt gcacatgttg
    14641 atatttttcg ggggctcaca gatgagtttg ttgtcggctt ctattacaag cctcatccgg
    14701 ttaatccatg ttcttcgaag gttttcaagg aagaatgggt tgtcatccgc gataaggcgc
    14761 ttttcccgaa ggtagatatg ttgatttcct atccctccac tctggtggag gagtacgagt
    14821 cgatggggat tcctggtatc attcatcctc taaacattca accctcttcg gtgggggaag
    14881 tatgtgattc ggcctcgcgg ctattggagg cgctaggctg cgaaaggaag gttgaccgac
    14941 agggccagga gtttttgagg aaaaaatgag caaccacagc tacaagattt gcacgcgctg
    15001 catcatggat acgtccgacc cccatattca ttttgatcag caaggtgtct gtgagtactg
    15061 tcaaaatttt gacgaggcaa tcaagccaaa ttggcacact gataagcatg gcgaagctga
    15121 gctcaagcgt ttggccgagg tgatcaaacg agatgggaaa ggtcgtgact ttgactgcat
    15181 tattggtttg agtggcggtc ttgatagctc ctacgtcagt tatgtggcga aggaaaaaat
    15241 ggggttacgc cctttattgt ttcatgtcga tgctggatgg aatacggatc aagctgtcgg
    15301 caatattgag aaacttgtag atgggctggg gctagattta tatacagagg tgattaattg
    15361 ggaggaaatg aaggacctcc aagtcgcttt cttgaaatct cagatttcag atcaagacct
    15421 gcctcaagat gctgcgttct tttcagcact ctataagttt gctcgtgctc ataaaatcaa
    15481 gtatgtgttg actggcggaa atttttctac tgaatgctgt cgtgagccgg aggagtgggg
    15541 tgggtatcca gggatcgata agcgtttatt taaggacata cataaacggt ttgggactcg
    15601 tacgctgaag accttcccta tagtagatat acttgcgtac aaaatctatt atcgatatgt
    15661 tctggggatg caggtgataa ggcctttaaa cctgctccct tacgttaaga aagatgcaga
    15721 agaaaccctt cagcgcttat acggttggca gtcatttcaa cataagcatc atgagtcacg
    15781 ttttactcgt ttctatgaag actactggtt gccccggaag tttggttatg aaaaaagaag
    15841 ggcgcacttc tctagtttga tcatgactgg ccaaatgacg cgcgaagagg cacttgaacg
    15901 tatttcgaaa ccagaaatgg atgagaactt tctacgctct gagtttgaat acgtggcaaa
    15961 taaactagat ctttccatcg aggatcttca gtttattttt gatggagaga acaagacatt
    16021 tcatgattat aagaataagc atttcatgat agggctgggt gctcgaatta tgaatactct
    16081 gggtttggaa cgtaggttat tcagatgatc actattattg actatgggat cggtaatata
    16141 caggcatttg tcaatgtcta caaacgtctg catatacctg cgcaggtggc tcgtgtaaat
    16201 tctgatctga agaacgtaga aaaactagtc cttcccgggg tgggttcatt cgatcatgcc
    16261 atgctgcgat ttactgagtc tggaatgcgt gaagctgttg agtttttggt gaaagataaa
    16321 ggtatacccg ttcttggtat ttgtgtgggt atgcagatgc tggctgacag aagtgatgag
    16381 ggtaagttac caggcttggg ttggattcct ggccacgttc gttcttttcg ctccgtaact
    16441 gggctgcaaa atattgcaat gccacatatg gggtggaatg acgtagtatc ggttggtaac
    16501 aatcctctgt ttaatggctt ggaacagggg gcgcgcttct attttttgca ttctttttac
    16561 tttgaaagct tgtatctcga acatgtcgct gcgggaactt tctacgggca tgacttcaat
    16621 agtgcagtct caagggacaa tattttcggt gtccagtttc atcccgagaa aagccaccac
    16681 tttggggtca agctcctaaa gaatttcgcg gaactctgaa atgctaaagc ctagaataat
    16741 tccttgcctg ctcatgcaag atggcggact tgtcaaaacc gtacgtttta aggatccacg
    16801 gtatatcggt gatccgatta atgcggtcaa gatttttaat gagaaagaag cggatgagct
    16861 gattatcctt gacatcgatg ctacctcgca gggtagagaa cctgattata agaagattgc
    16921 taaccttgct gccgagtgcc gtatgccctt gtgctatggt ggaggtattc gtaaaccaga
    16981 gcaagcgcgt ttaattattt ccctaggtgt cgaaaaagta gcaatcagtg ctgctgcaat
    17041 tgaggacgca aacttaatat ctaaagttgc tgaagaaata ggtcggcaaa gtgtcgtcgt
    17101 tgttctagac cataagcagc gactattgag caaacagcat gatgtttgga cacacaacgg
    17161 gacacataat accaagcgca atgtcattga cgtggcgaag cagatggagg atgcaggtgc
    17221 cggtgagatc gtgctcaact caattgacaa cgatggacgg ttgtgtggtt acgagatagc
    17281 gcttgccgtc cgtttacggg aagcagtgaa tgtacctgtt acaatacttg gtggcgccgg
    17341 ttcgctgaag gatatgggga gcttgattgc agcctgtgga gtggttggtg ctgcggctgg
    17401 cagtcttttt gtgtttaaag gcagctatcg agccgtcctg attaactatc ccagtttcca
    17461 gcaaaaaacc gatgtaatat tttcggtact gaactcccga taaaaagggc ggcctgcatt
    17521 caactcaggg ctcattatgt ttagcggaaa aagacttctt atttcaggtg gtacgggttc
    17581 tttcggtaat gctgtgctta aacgttttct cgacacagat attgcggaga tccgtatatt
    17641 tagccgtgac gaaaaaaaac aggatgatat gcggaagcat tatgccaata gtaaattgaa
    17701 gttctatgtt ggcgatgtgc gggactatca aagcgtgctc accgctacgc gcggggttga
    17761 ttatatattc cacgctgccg cgctaaaaca agttccttcg tgtgagtttc acccgatgga
    17821 ggctgtcaag actaatgtta tcgggacaga aaatttactt gaagcagcga tccagaatga
    17881 cgtgcgccgt attgtttgtt taagcacgga taaggctgtt tatcccatca atgccatggg
    17941 aatctccaaa gctatgatgg aaaaggtgat ggttgctaaa tcacgtaacc tcgaaaccac
    18001 ctcaactgtc atttgcggca ctcgttacgg caacgtgatg gcttcgagag gatcggtgat
    18061 tcccctgttc attgagcaga tgcgctctgg caagccgctg accatcacgg atcccagcat
    18121 gacccgcttc atgatgacgc tttctgatgc ggtggatctg gtgttatatg cgtttgagca
    18181 tggcaataat ggggatctgt tcgtacagaa agctccagct gctacgatcg aggtattggc
    18241 taaggcgctg accagcttgc tcggtaaaca agactatccg atcaacgtaa ttggcacccg
    18301 gcatggcgag aagctctatg aggctctctt gagccgtgag gaaatggctt gcgccgaaga
    18361 catgggtgac tattatcgcg tgccgccgga tctgcgcgat ttgaattaca gcaagtttgt
    18421 agagcaaggt gaagaaaaga tttcccatac ggaagactat aattcacata ataccgaacg
    18481 tctggatgtc aagggtatgc aggaactgtt actgaagctt gactttgttc gtgcgataca
    18541 acggggtgag caggcaaacc ccgaggagta gatcatgagg gtcttgataa ccggcgcaaa
    18601 tggtttcgta ggaaagaatc tcaccgcgca tctggccgag cggggggatg tcgaggttgt
    18661 aacctttacg cgtgaaagta atctccaaag cttgccagaa atgcttggct cgattgactt
    18721 tgtttttcat ttggctggtg ccaatcgacc cgagaatcca gaggacttca aatctataaa
    18781 ttctgatctg accaagacgc tgtgtgatgc cattcgggca actggtcgtt caattcctct
    18841 aatttatacc tcttcaacac aagcggagtt gcagaatagc tatggcttga gtaagcgcga
    18901 tgcagaggaa tacattcgaa gactgaactc cgaaacgggc tcgcctgtat atatattccg
    18961 tttacctaac gtgtttggga agtggtcgcg ccctaattac aactctgcgg tggcgacttt
    19021 ttgctataat atttccaggg atcttcctat tcaggtaaat gattcttcgg ctcaagtaac
    19081 acttgtatat attgatgatg taatccagaa atttctggct gtcttggacg ctccaaccgc
    19141 tactcatgat gtcagtgtcg agccacaata caagattacc gtgggtgatc ttgccaagca
    19201 gatacatgcc ttccgtgata gccgaaaatc gctcgttacg gaacaggtgg gagtaggtct
    19261 ggtacgggcc ttgtattcca cctatttgag tttcctccct gtaaatcgct tcagttacga
    19321 cctgccaatg tatggcgatg caagaggaac ctttgttgaa atgttgaaaa cgcccgatgc
    19381 tgggcagttc tcattcttta ctgcgcatcc tggcgtcact cgtggtggac actatcatca
    19441 ttccaaaacg gagaagttcc tggtgatcaa ggggactgcc cgcttcaagt tcaggaatat
    19501 ttctactgga gcatttcacg aattatgcac ccgtggtgag aaggctgaag tcgtcgagac
    19561 agttccaggc tggacgcatg atataacgaa tattggttcc gaagagatga tcgtcatgct
    19621 ctgggcgaac gaaatatttg atcgtgagcg tccggatacc tatgcttgcc cggttggcga
    19681 agtaagtgat ttgtaacgag gctctgatga agaagttaaa ggttgtcacg gtagtaggta
    19741 cgcgccccga gatcattcgc ctctctcgtg taatggcgaa gctcgacgag tattgtgacc
    19801 atgttctcgt ccatactggg cagaattatg actatgagct caacgagata ttctttcaag
    19861 acctaggaat ccgaaagccg gatcacttcc tgaacgctgc tggtgtatcc ggagcggaaa
    19921 ccattggaaa tgtaattatt gccgtcgatc gagtactttc ggtagagcag ccagacgcct
    19981 tgctggtatt gggagatacg aatagctgta tggcggtgct acccgccaag cgtcgaaaga
    20041 tcccaacttt ccatatggaa gcgggcaatc ggtgctttga tatgcgcgtt cccgaagaga
    20101 taaatcgacg aattgtcgat cacaccgcag atatcaatct cacttatagc accatcgctc
    20161 gggactactt gttgcgggaa ggtttgcccc ccgatatggt tatcaaaacc ggtagtccga
    20221 tgtttgaggt tttgaactac tatagggatg gtattgagag ctctgatgtg ttggcgcggc
    20281 tgggcctgga ggaaaataaa ttctttgtag tgagtgcgca tcgagaagaa aatatcgact
    20341 ctgaaagcaa cttcctttcg ttggtcgaga ccctgaatga aatttcggaa aagtatgaat
    20401 ttcccgtaat tgtttccacg catccgagaa cgatgaagcg tgtagaggca atgggcgtca
    20461 ggtttcatgc caatgtgcgc ttgctcaagc cgttgggttt caaggactac aataagttgc
    20521 aattgtcggc caaggcggtt ctttccgaca gcggtacgat caacgaagag tcctcgattc
    20581 tgaatttccc cgccttgaat atacgtcagg ctcatgagcg gccggagggt atggaggaag
    20641 cagcagtgat gatggtcgga ctcggtcgcg agcgcgtact gcaggggctg gagattctcg
    20701 agagccagtc tcgtggagct agccggctgc ttcatcttgt gcatgattat agttgtgata
    20761 atgtttctga gaaggtagtg cggattctcg taagctatcg ggactacgtt atgcgcaccg
    20821 tttggaagaa gtactagatt ctttatggat aagacgaagc tcaaggttct agttgttacg
    20881 cagtattttt ggccagaaaa tatgcgtatt aacgacttgg ttgctgactt tgttgggaga
    20941 gggcacgaag ttacggtttt gacggggtgc ccaaactatc ccgagggccg ggtcttttcc
    21001 gatttcaaag agaatccggc tagctattcc tgctatcttg gcgcttcggt gatcagggtt
    21061 cccatgcttc cacgcgggct gcatagcata cagcttgcct tgaactactt gtctttcttc
    21121 atgagtgcct cttttttcgg ggcgttcagg ctaagaagaa agaaatttga tgtggtcttt
    21181 gtttacgctg tttcaccaat aatggcagtc atacctgcga ttgtcattgg acgtctaaaa
    21241 agagcacccg tgtttgtctg ggtactggac ctttggccag agacattaag ggcagtgggg
    21301 gtcctcaaga gcgatcgagc tctttctata gtaggcaggg tggtatcttg gatctacaat
    21361 agaacggact atatattggt gcagtcaaaa gccttcatgg ataatgtggc gaagtattgt
    21421 accaagacca tacccgaaga cagggttatc tatttcccga gttgggccga ggatgatttc
    21481 tccaataatg aatcggcgag ttccaccctc ttggaaagag atgattccgt ttttaccctt
    21541 ctgtttgcgg gaaatgttgg agaggcgcag gattttccct ccattctgga tgccgcggag
    21601 cgtctccgcc aggatgttcc catgcgttgg gtgatcgttg gtgatggccg cgcaagtgca
    21661 tggcttaagg ccgaggttgc agccaggggg ttggataatg ttctgctgct gggccggcat
    21721 cctcttgagg agatgccgcc gctctttgcc ttggcggacg ctctatttgt gtcgctgaag
    21781 actaatgaag tattcgaaaa gaccattcca gggaaggttc aagcctactt ggcttccggc
    21841 aaaccggtga tcgcaatgat agatggagag gcatccaggg tgatctccga ggctggtgct
    21901 ggctacgcat gcgcttccgg cgacgtggag gctctggtgg acatcattcg tcgagccgcg
    21961 gcgctgacgg gggagcagcg agaagggctc ggtagagccg ggcgagaata ctatgaatgc
    22021 aatttttcga agcgaacact tttgagtcgc ctggaggggc tcttcattga cgcacgcttg
    22081 agaagggatg aaaaatgaac aaggttttat tgaccggtgc ttcaggattc gtgggtaaag
    22141 cattggcagg tgagcttctt cggcagggat atgcattgaa catggctttc cgacagactc
    22201 cttcaaaggt gctagaaggc gctgtcgcta ttccggtagg gaatatcgag ggtgacaccc
    22261 tttggagtga tgctcttgca ggcgtcgata ccgtcattca tagcgctgct cgtgtgcatg
    22321 tgatgaatga ccatgctctc gatcctttag ctgagttcag aaaggtgaat gtcgagggaa
    22381 cactgaatct cgcgcggcag gcagcggccg cgggagtcaa acgtttcgtc tttgtcagct
    22441 ccatcaaggt gaacggcgag tctacgacgg cgggcagtcc attcaagccc gacgatgttc
    22501 cagctccttc cgatccctat ggaatctcca agctcgaggc tgaaatcggt ctgcggcagg
    22561 tgtgtgaaga ggcagggatg gaatatgcca ttgttcgtcc tgttctggtc tacggccctg
    22621 gagtgaaagc caattttctc aatatgatga agtggttgga caaaggtatt cctttgcccc
    22681 ttggagccat aaaaaatcgg cgtagtctgg tgtcgctgac aaacttgatg gatatgctga
    22741 ttaccgtagc gagtcatcct gctgctgcta atcaggtatt tcttgtaagt gatggggagg
    22801 acctgtctac cactggtctt ttgcgaagaa tggcggcagc aatgggaaaa agagcgaatc
    22861 tgctgccagt ccctgaatcg ttgctgaaga ctgcagccct cttgttaggg aagaagtctg
    22921 taggtcagag gctctgcggg tctttgcagg tcgacatctc taagaataag cagttgttgg
    22981 attggaatcc gccgctttct gtggaccaag gtctgcaacg ggtcgctgaa tattacttgg
    23041 aatatcgctg aaatgtcgat ctggtggatt ttatttcctg tggttttggt atcggcagga
    23101 cttacaggag tattgaggtt ttacgccatc tcaaaaaagg tcatggatat tcctaacgcc
    23161 cgcagttctc acaccgtgcc tactccgaga ggcggtgggg tggctatcgt tctgactttt
    23221 ctcctagtgg ttttttttct tcccctattt tccattctgg aatggcgcca ggcgttactt
    23281 tttctgctgg gaggaggcgg cgtcgctctg cttggtttcc ttgacgacca tggtcacgtg
    23341 gctgcacgtt ggcgcctgct tgggcacttc atggctgcac tggtttcact cttccttctg
    23401 actggtgtgc cgccgttcaa gctactgggt tatcaatggg atttgggctg ggttggggtc
    23461 gtgctttttg ctttctatct cgtctggttg ctcaatcttt ataatttcat ggatggtata
    23521 gacggcctcg caagtctgga agctatcttt gtctgcgtgg gaggagcgct ggtgtattgg
    23581 atgaatgaca aggcagcgtt ttctttaccc cccctgttgc tggcttttgc tgttctcggt
    23641 ttcttgtttt ggaactttcc tcccgcgaag atcttcatgg gtgatgctgg tagtgggttc
    23701 ctgggattga ctctaggagt gctatcgatt caggccatgt gggttgagcc agagttcttc
    23761 tgggcatggc tgattctgct gggggtcttc atcgtggatg cgacctatac gctggcacga
    23821 cgcttattgc gcggcgacaa ggtgtatgaa gcccatcgga gccatgccta tcagtatgcc
    23881 tccaggcatt tcggcaagca tgctcctgtt acactcggcg taaccgtact gaatttggtt
    23941 tggcttctac ccctggcgct atgggtggca agtggccatc tcgagcctgt tctgggcatc
    24001 gccatagctt atacacccct cgttttcctg gctgtgaagt tcaaggctgg taagctagag
    24061 tcggttggat agaactcttc agctatagct attgagggag tatggaatgc tagatcgctt
    24121 tagagtaaaa ctgttgtcga tgcctcgtcg gtggaagcgt ttgcttcaag tggcaacaga
    24181 tatcctgttg gtgtggttat cgctgtggtt ggcatttgtc gtgcgtcttg gcacggacga
    24241 catgattgat attttcggcg agcatgcctg gctcttcatt gccgctccgc tcatcgccat
    24301 cccattgttc attcgcttcg gcatgtatcg cgcggtaatg cgctatctcg gtaacgatgc
    24361 attgatcgcc atcgccaagg cggtgaccat ctcggctctg gtgctgtcgc tggtagtgta
    24421 ctggtatcgt ggcgcgccgg cgccggtgcc acgttccctg gtgttcaact actggtggtt
    24481 gagcatgctg ctgatcggcg gcttgcgcct ggccatgcgc cagtatttca tgggcgactg
    24541 gtactctgct gtgcagtcgg taccatttct caaccgccag gatggcctgc ccagggtggc
    24601 tatctatggc gcgggggcgg ccggcaacca gttggttgcg gcattgcgtc tcggtcggac
    24661 gatgcgtccg gtggcgttca tcgatgatga caagcagatc gccaaccggg tcatcgccgg
    24721 tctgcgggtc tataccgcca agcatatccg ccagatgatc gacgagacgg gcgcgcagga
    24781 ggttctcctg gcgattcctt ccgccactcg ggcccggcgc cgagagattc tcgagtccct
    24841 ggagccgttc ccgctgcacg tgcgcagcat gcccggcttc atggacctgg ccagcggccg
    24901 ggtcaaggtg gacgacctgc aggaggtgga catcgctgac ctgctgggg
//
