LOCUS       E1                     15103 bp    DNA     linear       25-OCT-2021
DEFINITION  Genus species strain strain.
ACCESSION   
VERSION
KEYWORDS    .
SOURCE      Genus species
  ORGANISM  Genus species
            Unclassified.
COMMENT     Annotated using prokka 1.13 from
            https://github.com/tseemann/prokka.
FEATURES             Location/Qualifiers
     source          1..15103
                     /organism="Genus species"
                     /mol_type="genomic DNA"
                     /strain="strain"
     CDS             106..1191
                     /gene="rmlB"
                     /locus_tag="E1_00001"
                     /EC_number="4.2.1.46"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P26391"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /translation="MKILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLS
                     DISESNRYNFEHADICDSAEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEVARKYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTA
                     YAPSSPYSASKASSDHLVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KPLPIYGKGDQIRDWLYVEDHARALHMVVTEGKAGETYNIGGHNEKKNLDVVFTICDL
                     LDEIVPKATSYREQITYVADRPGHDRRYAIDAGKISRELGWKPLETFESGIRKTVEWY
                     LANTQWVNNVKSGAYQSWIEQNYEGRQ"
     CDS             1191..2090
                     /gene="rmlD"
                     /locus_tag="E1_00002"
                     /EC_number="1.1.1.133"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P26392"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /translation="MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEFCGDFSNPK
                     GVAETVRKLRPDVIVNAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHY
                     STDYVFPGTGDIPWQETDATSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKERQTLSVINDQYGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAG
                     GTTTWHDYAALVFDEARKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFD
                     LILPQWELGVKRMLTEMFTTTTI"
     CDS             2138..3016
                     /gene="rmlA"
                     /locus_tag="E1_00003"
                     /EC_number="2.7.7.24"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P26393"
                     /codon_start=1
                     /transl_table=11
                     /product="Glucose-1-phosphate thymidylyltransferase"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGN
                     DDCALVLGDNIFYGHDLPKLMEAAVNKESGATVFAYHVNDPERYGVVEFDQSGTAVSL
                     EEKPLQPKSNYAVTGLYFYDNSVVEMAKNLKPSARGELEITDINRIYMEQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDAEQIKNLAKPL
                     SKNAYGQYLLNMIKGY"
     CDS             3021..3551
                     /gene="rmlC"
                     /locus_tag="E1_00004"
                     /EC_number="5.1.3.13"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P26394"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /translation="MNVIKTEIPDVLIFEPKVFSDERGFFMESFNQKVFEEAVGRKIE
                     FVQDNHSKSTKGVLRGLHYQVEPYAQGKLVRCIAGEVFDVAVDIRNDSETFGKWVGVN
                     ISSENKRQLWIPEGFAHGFLVLSEEAEFVYKTSNYYSGEHERGIIWNDPDINITWGID
                     SPILSLKDKIHKGLVK"
     CDS             3898..5436
                     /locus_tag="E1_00005"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /codon_start=1
                     /transl_table=11
                     /gene="wzx"
                     /product="flippase"
                     /translation="MFRNKVALGSQIGLFTSVLILITNFFLRSYFVKVYGADLTGYYL
                     LVVQLMGVLNLAELGISTALTYILFKPLHRKENSELRQLYFIIKKIYHFIALGILVIG
                     LLFFLLLNSIVNASISPENLYITWGVFVISTSLSYLYSAQSVILTADQNVYLVKLITG
                     LTRSLAYILQIFLMICGVSFWIVCAIELLSNVIQLILFNKLTLKKYPQLVKLDITDTI
                     NKENIISVKSKIKREIKYTFVHKIAGVVVFNTDYLIISVFLGITVITSFSSYMMLIQA
                     LAFLISAIASPLGAYIGAKLYSDSKEKVIRIISLYNSLFFMLGIFCAYMFYISSSTFV
                     SLWMGKEIVLSQQLVLLLSVNCFVLIARISFDVAKVGLGYMSDIELPLLEAIINIIVS
                     LVLVHYLGLNGIVIGTIVSNIIVVMILKPVFLYKNALKSDNAFIIHELIRSWFFISIF
                     LLSIFFITRAKVIVSNEWLDFFIQVCMSSITPLLLLIMIYSVFDSNVRKFMFVMFKKK
                     YREN"
     CDS             5625..6803
                     /locus_tag="E1_00006"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /codon_start=1
                     /transl_table=11
                     /gene="wzy"
                     /product="polymerase"
                     /translation="MVFLAWFIAIGIYIICGILYLQFPQLSPLGALAYTDTVGDVIMV
                     VSTGVVGVFLGYFAFSKIKLAGIKDFNNSCFINFCSVCFIISAFLIFALGVAAYGGYI
                     AFLHTPYIAIYEGSAENQTRDILISSSGLLANYALLTSIRVNFKEISITNKVVIAVSL
                     LILVSIFIQGRRENLILLILCFVSFYMLNYKINFKRIIKVSIICIIMFFIAGLGLYLR
                     ESTSTSGGSVFTAIPFAVMYETHFSLATLANEVRTHLYNNLPYGGVLDLFSPILFIIP
                     AFIYGIFGLDKQSLFENNEMRFYEDKGGQFIFTEAFHSLGYVGVFLHGLILGVMLIVF
                     YRVAKKSRLIIYHFPIISLIFVAMRKDLTYGVKYISLLFIFMMIFYFIYKLLPLKNNG
                     "
     CDS             6796..7881
                     /locus_tag="E1_00007"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /codon_start=1
                     /transl_table=11
                     /gene="wbaO"
                     /product="glycosyltransferase"
                     /translation="MVELKMHKVLFISAFHPGARGSIGAGEAICGDNLKKHVNNGSQV
                     DVIVISPATQYENPEIKALCHSYEVINVSKKDYLKGILFNAKYKSFIAPWFFTRVNKS
                     LIKRINNKISHTNYDLVWLDFPSVLGVVKHILHPNIHYFAHDVVSQRTSRSLTKKPIN
                     KEIAKVEANLFCKLKKIVAMSHKDKLLLEQMNYKGVIEVADLGVQKVGEVLNCIPIEE
                     VVDKFKDRKNLIFFGYMKRAENHWSIIWFIFFVFLKIRKQNPHIHLWILGLAPRPLLK
                     LIGKCISNVHVAGAVSDPTLAFQKADLSVAPLLYGAGVKIKVLQMLEAGATVVATEVG
                     AEGIESHKKLHIVNKTQFGKKILELLD"
     CDS             7885..8832
                     /locus_tag="E1_00008"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /codon_start=1
                     /transl_table=11
                     /gene="wbaN"
                     /product="glycosyltransferase"
                     /translation="MPSFTLIVPTYNAGTARWNEWFHAFQKQTNQPSQLIIIDSSSTD
                     DTRNIASTYTNNIIVISPSEFNHGGTRNKALASAEESDFVVFLTQDAIFENKNALEEI
                     LSLFNDKNVAAVCGRQLPHHDANPLAIHARNFNYGTETLIKSKNDIKNLGIKTVFMSN
                     SFAAYRRSVFEALGGFPEHTILAEDMFMAARMIQAGYKIAYCAEASVRHSHNYTPKQE
                     FQRYFDTGVFHACNPWIQRDFGGAGGEGFRFVKSEIQFLLKNAPFWIPRALLTTFAKF
                     LGYKLGKHWQSLPLSTCRYFSMYKSYWNNIQYSSSKEIK"
     CDS             8833..10272
                     /gene="manC"
                     /locus_tag="E1_00009"
                     /EC_number="2.7.7.13"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P26404"
                     /codon_start=1
                     /transl_table=11
                     /product="Mannose-1-phosphate guanylyltransferase RfbM"
                     /translation="MSFLPVIMAGGTGSRLWPLSREYHPKQFLSVEGKLSMLQNTIKR
                     LASLSTEEPVVICNDRHRFLVAEQLREIDKLANNIILEPVGRNTAPAIALAAFCALQN
                     ADNADPLLLVLAADHVIQDEIAFTKAVRHAEEYAANGKLVTFGIVPTHAETGYGYIRR
                     GELIGNDAYAVAEFVEKPDIDTAGDYFKSGKYYWNSGMFLFRASSYLNELKYLSPEIY
                     KACEKAVGHINPDLDFIRIDKEEFMSCPSDSIDYAVMEHTQHAVVIPMSAGWSDVGSW
                     SSLWDISNKHHQRNVLKGDIFAHACNDNYIYSEDMFISAIGVSNLVIVQTTDALLVAN
                     KDTVQDVKKIVDYLKRNDRNEYKQHQEVFRPWGKYNVIDSGKNYLVRCITVKPGEKFV
                     AQMHHHRAEHWIVLSGTARVTKGEQIYMVSENESTFIPPDTIHALENPGMIPLKLIEI
                     QSGTYLGEDDIIRLEQRSGFSKEWTNERS"
     CDS             10259..11692
                     /gene="manB"
                     /locus_tag="E1_00010"
                     /EC_number="5.4.2.10"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:O34824"
                     /codon_start=1
                     /transl_table=11
                     /product="Phosphoglucosamine mutase"
                     /translation="MNVVNNSRDVIHSSGIVFGTSGARGLVKDFTPQVCAAFTVSFVA
                     VMQEHFSFDTVALAIDNRPSSYGMAQACAAALADKGVNCIFYGVVPTPALAFQSMSDN
                     MPAIMVTGSHIPFERNGLKFYRPDGEITKHDEAAILSVEDTCSHLELKELIVSEMAAV
                     NYISRYTSLFSTPFLKNKRIGIYEHSSAGRDLYKPLFIALGAEVISLGRSDNFVPIDT
                     EAVSKEDREKARSWAKEFDLDAIFSTDGDGDRPLIADEAGEWLRGDILGLLCSLALDA
                     EAVAIPVSCNSIISSGRFFKHVKLTKIGSPYVIEAFNELSRSYSRIVGFEANGGFLLG
                     SDICINEQNLHALPTRDAVLPAIMLLYKSRNTSISALVNELPTRYTHSDRLQGITTDK
                     SQSLISMGRENLSNLLSYIGLENEGAISTDMTDGMRITLRDGCIVHLRASGNAPELRC
                     YAEANLLNRAQELVNTTLANIKKRCLL"
     CDS             11764..13194
                     /gene="wbaP"
                     /locus_tag="E1_00011"
                     /EC_number="2.7.8.31"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P71241"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /translation="MDNIDNKYNPQLCKIFLAISDLIFFNLALWFSLGCVYFIFDQVQ
                     RFIPQDQLDTRVITHFILSVVCVGWFWIRLRHYTYRKPFWYELKEIFRTIVIFAIFDL
                     ALIAFTKWQFSRYVWVFCWTFAIILVPFFRALTKHLLNKLGIWKKKTIILGSGQNARG
                     AYSALQSEEMMGFDVIAFFDTDASDAEINMLPVIKDTETIWDLNRTGDVHYILAYEYT
                     ELEKTHFWLRELSKHHCRSVTVVPSFRGLPLYNTDMSFIFSHEVMLLRIQNNLAKRSS
                     RFLKRTFDIVCSIMILIIASPLMIYLWYKVTRDGGPAIYGHQRVGRHGKLFPCYKFRS
                     MVMNSQEVLKELLANDPIARAEWEKDFKLKNDPRITAVGRFIRKTSLDELPQLFNVLK
                     GDMSLVGPRPIVSDELERYCDDVDYYLMAKPGMTGLWQVSGRNDVDYDTRVYFDSWYV
                     KNWTLWNDIAILFKTVKVVFHRNGAY"
     CDS             13372..14475
                     /locus_tag="E1_00012"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf17.4"
                     /product="hypothetical protein"
                     /translation="MEKNSFPISHEHSLTMDYVKAFGMIFVLVGHINNDIFNVYYAYL
                     FHMPLFFFIGGVLYKDTRCITNFTAHVIKKQLPYLIVTYLIIGSIALLINVRYGIHTG
                     DAFSTGLYETVKLAIKSNFHNNKMFLTGWFLFAYIFVSILSVIIIKSIKRVVVSNALL
                     LSVLVAISVLLITVSITYLSPQYILVKDYKLNFICQVLTGMSFYIFGYVIRNQIYNLL
                     NFYVFILLTVILYVSKSYGFSTQTIMSWSYYPDGLIMSVINALIGIYAVFFISLLITR
                     GMKEIKLLKMIGQNSRAIMAYHLLVYVILDIIASILGDYSLSGTDVYDNHFITKWSVP
                     VYIALGLLLPLIFSILKQKVIGKIKFKRDFRIN"
BASE COUNT     4516 a   2460 c   3145 g   4982 t
ORIGIN
        1 attggtagct gtaagccaag ggcggtagcg tgtgtaacga cttgagcaat taatttttat
       61 tggcaaatta aataccacat taaatacgcc ttatggaata gaaaagtgaa gatacttatt
      121 actggcgggg caggttttat tggatcagct gttgtccgcc atattattaa gaatacacag
      181 gacactgtag ttaatattga taaattaacc tacgccggta atcttgaatc cctttctgat
      241 atttctgaaa gtaatcgcta caattttgaa cacgcggata tttgtgattc cgctgaaata
      301 acgcgtattt ttgagcagta ccagccggac gcggtgatgc atttggctgc ggaaagtcat
      361 gtggaccgtt cgattaccgg gccggcagca tttattgaaa ccaatatcgt tggcacctat
      421 gtacttcttg aagttgcgcg taaatactgg tctgcgcttg gcgaagataa aaaaaataat
      481 tttcgttttc atcatatttc cactgatgaa gtttacggcg atttaccgca tcctgatgaa
      541 gttgaaaaca gcgttacgct gccgttattt actgaaacga cggcatatgc gccaagtagc
      601 ccctattctg cgtcaaaagc atccagcgat catttagtcc gtgcctggcg gcgtacctat
      661 ggtctaccaa cgatcgttac caattgttct aataactatg gcccttatca cttccctgaa
      721 aaactgattc cgctggtcat tttgaacgcg ctggaaggaa agcctttgcc aatttatggc
      781 aaaggggatc agattcgcga ttggctatat gtagaagatc acgctcgcgc gcttcatatg
      841 gtagtgactg aaggcaaggc gggggagact tataacattg gtggccacaa tgagaagaaa
      901 aatctcgatg tggtatttac catctgtgat ctgctggacg agattgtacc caaagcgact
      961 tcttatcgtg aacaaatcac ttatgtcgcg gatcgtccgg gccatgatcg tcgttatgcc
     1021 attgatgcag gtaaaattag ccgcgaatta ggctggaaac cgctggagac ctttgaaagc
     1081 ggtattcgta aaacagtgga atggtacctt gcaaatactc aatgggtaaa caatgttaaa
     1141 agtggggcgt atcagagttg gatagaacag aactatgaag gacgccagta atgaatatct
     1201 tactttttgg taagacaggg caagtaggct gggagttgca acgttctctg gcaccagtag
     1261 ggaatctgat tgccctggat gtccattcaa aagagttttg cggtgatttt agtaatccga
     1321 aaggcgttgc cgaaaccgtt cgtaagcttc gtcccgatgt gattgttaac gcagcagcac
     1381 atactgcagt agataaagca gagtctgaac cagaactggc gcagttactt aacgccacca
     1441 gtgtggaagc catcgctaaa gcagccaacg aaactggcgc atgggtagtg cattattcaa
     1501 ccgattatgt atttcctggt accggcgata tcccatggca ggaaacggac gctacgtcgc
     1561 cgctgaatgt ctatggcaag accaaactgg cgggagaaaa ggccctgcag gataactgcc
     1621 ctaagcatct tatcttccgc accagttggg tttatgcagg taagggcaat aatttcgcaa
     1681 agacaatgct tcgtctggcg aaagagcgtc agacactttc agtcatcaac gatcagtacg
     1741 gtgcgccgac cggtgcggaa ttactggctg actgcacggc gcatgcgatc cgtgtggcgt
     1801 taaataaacc agaagtcgca ggtctttacc atctggttgc cgggggaacc acaacctggc
     1861 atgactacgc ggccttagtc tttgacgagg cgcgcaaggc agggataacg cttgcgctga
     1921 ctgagcttaa tgctgtgccg accagcgcct acccgacgcc ggcgagcaga cctggaaatt
     1981 cgcgtctcaa tactgaaaag tttcagcgta attttgacct tattctgccg caatgggaat
     2041 taggagttaa gcgtatgctg actgaaatgt ttacgacgac aaccatctga taaatttaaa
     2101 tgcccatcag ggcattttct atgaatgaga aatggaaatg aaaacgcgta agggcattat
     2161 tttagcgggg ggctccggca cccgtcttta tccggtgacc atggcggtaa gtaagcaatt
     2221 gctaccaatt tatgataaac cgatgattta ctatcccctt tccacactta tgctggcagg
     2281 tattcgggat atcctgatca tcagtacgcc acaggacacg ccgcgttttc aacaactgct
     2341 gggagacggc agccagtggg ggctgaatct tcaatataaa gtacagccaa gcccggatgg
     2401 cttagcacag gcgtttatta ttggtgaaga gttcattggt aatgatgatt gtgcattagt
     2461 actgggtgac aatatcttct atggtcatga tttaccaaag ttaatggaag ctgccgttaa
     2521 taaagaaagt ggtgctaccg tctttgctta tcatgtaaac gatccagagc gctacggtgt
     2581 ggttgagttt gaccaaagtg gcacagccgt tagtctggag gaaaaaccgt tacaaccgaa
     2641 gagtaattac gcggtaacgg ggctgtattt ttacgataac agcgtggtgg agatggcgaa
     2701 aaatcttaag ccttccgctc gcggtgagtt agaaatcacg gatattaacc gtatctatat
     2761 ggagcaggga agattgtctg tcgctatgat ggggcgcggt tatgcttggc tggatacggg
     2821 aacgcatcag agtttgatag aggccagtaa ttttattgca accatcgaag aacgccaggg
     2881 tctgaaagtg tcttgcccgg aagagatcgc ttatagaaaa gggtttattg atgcagagca
     2941 gattaaaaat ctggctaaac cgttgtcgaa gaatgcttat gggcagtatc tcctgaacat
     3001 gattaaaggt tattaataaa atgaacgtta ttaaaacaga aattcctgat gtattaattt
     3061 ttgaacctaa agtgtttagt gatgaacgtg ggttctttat ggaaagtttt aatcagaaag
     3121 tatttgagga agcggttggt cgaaagattg aatttgttca ggataatcat tcaaaatcaa
     3181 ctaaaggtgt gttacgtggt ctacattatc aagttgaacc ttatgctcaa gggaagcttg
     3241 tacgctgtat agcgggagaa gtttttgatg ttgctgtaga tattcgcaac gattccgaaa
     3301 cgtttggtaa atgggttggt gtcaatattt cttctgaaaa caaaaggcag ttgtggatac
     3361 ctgaaggttt tgctcatggg ttcttagtat taagtgaaga agctgaattt gtttataaga
     3421 catcaaacta ttactctggc gaacatgaaa gaggtattat ttggaatgat cctgatatta
     3481 atattacatg gggaatagat agtccaattc tttcattaaa agataagatt cataaaggtt
     3541 tagtaaagta acacaattgc cattatttat aattgaatag atattgttca acacctataa
     3601 gcgttttata ggtgttatta aaattttcta atcctattta ttgcattgta attaaaattt
     3661 agagagttat agagatattt taaagagctt agtctattca tctgttgtat gaacgatgtg
     3721 tgaatacggg ttttttagac aaaataacca aattagatag atttcaaaaa tatcagacag
     3781 atatttactt ggaataagta aagtcagttc aagaaaataa aaatatgata ttagaaacta
     3841 tcattcaaca ttccttttta gctaacaaaa tacagatgat tcgagtttta tcctaatatg
     3901 tttagaaata aagttgctct tgggtctcag ataggattgt ttacttcagt tcttatatta
     3961 ataacaaact tttttttaag aagttacttt gttaaagtat atggtgctga tttaaccggg
     4021 tattatttat tagtagtaca gttgatggga gtattaaatc ttgctgagct aggtataagt
     4081 acagccttaa catatatcct atttaaacca ctgcatagaa aagaaaatag tgagttaaga
     4141 caattatatt ttataataaa gaaaatatac cattttatag cattgggcat attagttatt
     4201 ggactacttt tctttttgtt attaaattct atagtaaatg caagtatatc ccctgaaaat
     4261 ctatatataa catggggggt gtttgttata agtacatcat tatcatattt atactctgct
     4321 caatctgtca ttttaacagc agaccagaat gtctatttgg ttaaattaat tactgggtta
     4381 actagaagtt tagcgtatat attgcaaata tttctaatga tttgcggcgt ctccttttgg
     4441 attgtgtgcg ctattgaatt actttctaat gtaatacaac ttattctttt taacaaacta
     4501 acattaaaaa aatatccgca attagtaaag ttggatatta ctgatactat caataaagaa
     4561 aatataataa gtgtaaaatc taaaataaaa agagagataa aatatacgtt tgtacataaa
     4621 attgccggtg ttgttgtatt taatacagat tatttaatta tatctgtctt tctaggtata
     4681 acggttatca catctttttc ttcctatatg atgttaattc aagcattggc ttttctgata
     4741 tcagcaatag cttccccact gggtgcctat ataggagcaa aactatattc tgatagtaag
     4801 gaaaaagtta tcaggattat atcactttat aattcacttt tttttatgct aggtattttt
     4861 tgcgcgtata tgttttatat atcttcaagt acatttgtat ccttatggat gggaaaagaa
     4921 attgtactta gccaacaatt agttttgtta ctttctgtta attgcttcgt attgattgca
     4981 aggatctctt ttgatgttgc aaaagtaggc cttggttata tgtcagatat tgaattaccc
     5041 ctactggaag ccataattaa tattatcgtt tcattagttt tagtacatta tttaggttta
     5101 aatgggatag ttattggaac tatcgttagt aatatcatcg ttgtcatgat cttgaaacca
     5161 gtatttttat acaaaaatgc ccttaaatcg gataatgcat ttattattca tgagcttata
     5221 aggtcatggt tctttataag catattcttg ctttccatct tttttattac aagggcaaaa
     5281 gttatagtca gcaacgaatg gctagatttc tttatacaag tgtgtatgag tagcattact
     5341 cctttattgt tattgataat gatatacagc gtctttgata gcaacgttcg gaaattcatg
     5401 tttgttatgt ttaaaaaaaa gtatagggaa aattgattct ctaaaattgg agaaaaagat
     5461 cgttgccttg atagtttgat aatgaaaccg atatatatta agcgtagtgg tgtacgcaaa
     5521 agcgactatt tggctattga aaataaggta taaatctaaa caagataaat atatgtaata
     5581 aagtattatc ttattcctta tcgcttaata atatgagatg tgttatggta tttttagctt
     5641 ggtttattgc tattgggata tatataatat gtggaattct ttatcttcaa tttcctcaat
     5701 tatcaccact aggggccctt gcatatactg atacagtggg cgatgtaatc atggtcgtat
     5761 ccacgggggt agtgggagtt tttctcggct attttgcatt ttctaaaatc aagttagcag
     5821 gaataaaaga ttttaataat tcgtgtttta taaatttttg ttcagtatgc tttattattt
     5881 cagcgtttct aattttcgcc ttaggtgtcg ctgcatatgg tggttacata gcatttctac
     5941 atacgcctta tatagcaatc tatgaaggta gtgcagaaaa tcaaaccaga gatattctca
     6001 tatcttcatc gggattgctt gctaactatg cactattaac tagcattcgt gtcaacttta
     6061 aagaaatatc aataactaat aaagttgtca tagcagtatc gctattaata cttgtttcta
     6121 tatttattca gggacgaaga gaaaatttaa ttttgctaat attatgtttc gtgtcattct
     6181 atatgctaaa ttataaaatt aattttaaac gtattatcaa agtaagcatt atttgtataa
     6241 taatgttttt cattgctgga ttaggtttat atttgcgtga aagcacttca acttcaggtg
     6301 gaagtgtttt tacagctata ccttttgccg tgatgtatga aacacatttt tctttagcga
     6361 ctttggctaa tgaagtgaga acgcatttat ataataattt accttatggg ggagtattag
     6421 atttattttc tcccatatta tttattatcc ctgcttttat atatggcatt tttggtttag
     6481 ataaacaatc tttgttcgag aataatgaga tgcgttttta tgaggataaa ggtgggcagt
     6541 ttatattcac agaggctttt cattcacttg gttatgtcgg agtattcctg catggtttaa
     6601 tcttgggtgt aatgctaata gtattttatc gtgtagccaa gaaaagcagg ctcataattt
     6661 atcattttcc aattatttcc ctcatatttg ttgcaatgag aaaagacctt acctatggtg
     6721 ttaaatatat ttctctttta ttcatattta tgatgatttt ttatttcatc tataagttac
     6781 tcccacttaa aaataatggt tgaattaaaa atgcataaag ttctttttat tagtgccttt
     6841 catcctgggg cgagaggttc gatcggtgct ggtgaggcca tttgtggtga taatttaaaa
     6901 aaacatgtaa ataatggcag tcaagtcgat gttattgtta tatctcctgc aacacaatat
     6961 gaaaatccag aaattaaagc actatgccat tcttatgaag taatcaacgt tagtaagaaa
     7021 gattatctta aagggatact tttcaatgct aaatataaat cttttattgc gccatggttt
     7081 tttactagag taaataaaag cttaattaaa cggataaata ataagatctc tcacacgaat
     7141 tacgacttag tatggcttga ttttccatca gttttaggag tggtaaaaca tattttacat
     7201 ccaaatattc attattttgc ccatgatgtt gtatcacagc gcacaagtcg ttctcttaca
     7261 aagaaaccta tcaataaaga gattgcaaaa gttgaggcaa acttattctg taagttgaaa
     7321 aaaattgtgg caatgtctca taaagataaa ttgttacttg aacaaatgaa ttataaagga
     7381 gttatagagg ttgctgatct tggagtacaa aaagttggtg aggtattaaa ttgtattccg
     7441 attgaagagg ttgtagataa atttaaggat agaaaaaatt taattttttt tggttacatg
     7501 aagcgtgcgg aaaaccactg gtctataata tggtttatat tttttgtttt tcttaaaata
     7561 agaaaacaaa atccacatat ccatctttgg attttaggct tggctcccag acctttactg
     7621 aagttgatcg gcaagtgtat atctaacgta catgtcgctg gtgctgtatc agatcctacc
     7681 ttggcttttc aaaaggccga tttaagtgtt gcacctttac tatatggagc tggagtaaaa
     7741 ataaaggtgt tacagatgct tgaggcgggt gcaacggttg ttgctactga ggttggggct
     7801 gaaggtattg aaagccataa aaagcttcac attgttaata aaacacaatt tggtaaaaaa
     7861 atacttgagc ttttggacta aaaaatgccc tcctttactt taattgttcc tacatataat
     7921 gctggtactg ctagatggaa tgagtggttt cacgcttttc aaaaacaaac taatcagcca
     7981 tcacaattga taatcattga ttcatcatcg acagatgaca ctagaaatat tgcaagcact
     8041 tataccaaca atattatagt tatatcacca agtgaattta atcacggagg gacgagaaat
     8101 aaagcattag cttctgccga agaaagtgat tttgttgttt ttttaaccca ggatgctata
     8161 tttgaaaaca aaaatgccct ggaagaaata ttatcattat ttaatgacaa aaatgtcgct
     8221 gcagtatgtg gcagacagct tcctcatcat gatgctaatc ctcttgctat acacgcaaga
     8281 aattttaatt atggtactga aactctaatt aaaagtaaaa atgatataaa aaatctcggc
     8341 attaaaaccg tgtttatgtc aaattctttt gcagcttatc ggcggtctgt ttttgaagca
     8401 cttggggggt ttcctgaaca tactatcctc gctgaagata tgtttatggc tgcgagaatg
     8461 atccaggcgg ggtataaaat tgcttattgc gcagaagcca gcgtaaggca ttcgcataat
     8521 tatacgccaa aacaagagtt ccaacggtat tttgatacag gggtatttca tgcctgtaac
     8581 ccttggattc agcgtgactt tggcggagcc ggtggtgagg gtttccgctt cgtaaaatca
     8641 gagattcaat ttctgcttaa aaatgcaccg ttctggattc caagagcttt attaacaacc
     8701 tttgctaaat ttctgggtta caaattaggc aagcattggc aatctttacc gttgtctaca
     8761 tgtcgctatt ttagcatgta caagagttat tggaataata tccaatattc ttcgtcaaaa
     8821 gagataaaat aaatgtcttt tcttcccgta attatggctg gcggcacagg tagccgttta
     8881 tggccgcttt cacgcgaata tcatccgaag cagtttctaa gcgttgaagg taaactatca
     8941 atgctgcaaa atactataaa gcgattagct tcactttcta cagaagaacc cgttgtcatt
     9001 tgcaatgaca gacaccgttt cttagtcgct gaacaactcc gtgaaattga caagttagca
     9061 aataatatta ttctcgaacc agtaggccgt aatactgcac cagcgatcgc tcttgccgcg
     9121 ttttgtgcgc tccagaatgc tgataatgct gatcctcttt tgttggttct tgctgcagat
     9181 catgtgatcc aggatgaaat agcttttacg aaagctgtca gacatgctga agaatacgcc
     9241 gcaaatggta agcttgtaac ttttggtatt gttccaacgc atgctgaaac gggttatgga
     9301 tatattcgtc gtggtgagtt gataggaaat gacgcttatg cagtggctga atttgtggag
     9361 aaaccggata tcgataccgc cggtgactat ttcaaatcag ggaaatatta ctggaatagc
     9421 ggtatgtttt tatttcgtgc aagctcttat ttaaacgaat tgaagtactt atcacctgaa
     9481 atttacaaag cttgtgaaaa ggcggtagga catataaatc ccgatcttga ttttattcgt
     9541 attgataaag aagagtttat gtcatgcccg agtgattcta tcgattatgc agttatggag
     9601 cacacacagc atgccgtggt gataccaatg agcgctggct ggtcggatgt gggatcctgg
     9661 tcctcactat gggatatatc gaataaacat catcagagaa atgtcttaaa aggagatatc
     9721 ttcgcacatg cttgtaatga taattacatt tattccgaag atatgtttat aagtgcgatt
     9781 ggtgtaagca atcttgtcat tgttcaaaca acagacgctt tactggtggc taataaagat
     9841 acagtacaag atgttaaaaa aattgttgat tatttaaaac gaaatgatag gaacgaatat
     9901 aaacaacatc aagaagtttt ccgcccctgg ggaaaatata atgtgattga tagcggcaaa
     9961 aattacctcg ttagatgtat cactgttaag ccgggtgaga aatttgtggc gcagatgcat
    10021 caccaccggg ctgagcattg gatagtatta tccgggactg ctcgtgttac aaagggagag
    10081 cagatttata tggtttctga aaatgaatca acatttattc ctccggatac tattcacgcg
    10141 ctggaaaatc ccggaatgat ccccctgaag ttaattgaga ttcaatcagg tacctatctt
    10201 ggtgaggatg atattattcg tttagaacaa cgttctggat tttcgaagga gtggactaat
    10261 gaacgtagtt aataatagcc gtgatgttat tcattcatca ggtattgtgt ttggaacgag
    10321 tggagctcgc ggtcttgtaa aagattttac acctcaggta tgtgctgctt ttacggtttc
    10381 atttgttgcc gttatgcagg aacatttttc ctttgatacc gtagcattgg caatagataa
    10441 tcgtccaagt agttatggga tggctcaggc gtgtgctgct gcattggcgg ataaaggcgt
    10501 taactgtatt ttttatggag tggtaccaac cccagctttg gcctttcagt ctatgtctga
    10561 caatatgcct gcgataatgg ttacgggaag tcatattcca ttcgagcgga acggcctcaa
    10621 gttctatcgt cccgatggtg aaatcacgaa acatgatgag gctgcgatcc tcagtgttga
    10681 agatacgtgt agccatttag agcttaaaga actcatagtt tcagaaatgg ctgctgttaa
    10741 ttatatatct cgttatacat ctttattttc tactccattc ctgaaaaata agcgtattgg
    10801 tatttacgaa cattcaagcg ctgggcgtga tctttataag cctttattta ttgcattggg
    10861 ggctgaagtc attagcttgg gtagaagcga taactttgta cctatagata cagaggctgt
    10921 aagcaaagag gatcgggaaa aagcacgctc atgggctaaa gagttcgatt tagatgccat
    10981 attctcaaca gatggggatg gtgatcgccc tcttattgct gatgaggcag gcgagtggtt
    11041 gagaggcgat atattaggtc tattatgttc acttgcattg gatgcagaag ccgtcgctat
    11101 tcctgttagt tgtaatagca taatttcttc tggccgcttt tttaaacatg ttaagcttac
    11161 gaaaattggc tcgccttatg ttatcgaagc ttttaatgaa ttatcgcgga gttatagtcg
    11221 tattgtcggc tttgaagcca atggcggttt tttattagga agcgacatct gtattaacga
    11281 gcagaatctt catgccttac caactcgtga tgctgtatta ccagcaataa tgctgcttta
    11341 caaaagtagg aataccagca ttagcgcttt agtcaatgaa ctcccaactc gttacaccca
    11401 ttctgacaga ttgcagggga ttacgactga taaaagtcaa tccttaatta gtatgggccg
    11461 agaaaatctg agcaacctct taagctatat tggcttggag aatgaaggtg caatttctac
    11521 agatatgaca gatggtatgc gaattacctt acgtgatgga tgtattgtgc atttgcgcgc
    11581 ttctggtaat gcacctgagt tacgctgcta tgcagaagct aatttattaa atagagctca
    11641 ggaacttgta aatacaacgc ttgctaatat taaaaaacga tgcttgctgt aaaagaattg
    11701 aatgttatta acttaatatg cctattttat ttacattatg cacggtcaga gggtgaggat
    11761 taaatggata atattgataa taagtataat ccacagctat gtaaaatttt tttggctata
    11821 tcggatttga ttttttttaa tttagcctta tggttttcat taggatgtgt ctattttatt
    11881 tttgatcaag tacagcgatt tattcctcaa gaccaattag atacaagagt tattacacat
    11941 tttattttgt cagtagtatg tgtcggttgg ttttggattc gtttgcgaca ttatacatac
    12001 cgcaagccat tttggtatga gttaaaagaa atttttcgta cgatcgttat ttttgctata
    12061 tttgatttgg ctctgatagc gtttacaaaa tggcagtttt cacgctatgt ctgggtgttt
    12121 tgttggactt ttgccataat cctggtgcct ttttttcgcg cacttacaaa gcatttattg
    12181 aacaagctag gtatctggaa gaaaaaaact atcatcctgg ggagcggaca gaatgctcgt
    12241 ggtgcatatt ctgcgctgca aagtgaggag atgatggggt ttgacgttat cgcttttttt
    12301 gatacggatg cgtcagatgc tgaaataaat atgttaccgg tgataaagga tactgagact
    12361 atttgggatt taaatcgtac aggtgatgtc cattatattc ttgcttatga atacaccgag
    12421 ttggagaaaa cacatttttg gctacgtgaa ctttcaaagc atcattgtcg ttctgttact
    12481 gtagtcccct cgtttagagg attaccatta tataatactg atatgtcttt tatctttagc
    12541 catgaagtta tgttattaag gatacaaaat aacttggcta aaaggtcgtc ccgttttctc
    12601 aaacggacat ttgatattgt ttgttcaata atgattctta taattgcatc accacttatg
    12661 atttatctgt ggtataaagt tactcgagat ggtggtccgg ctatttatgg tcaccagcga
    12721 gtaggtcggc atggaaaact ttttccatgc tacaaatttc gttctatggt tatgaattct
    12781 caagaggtac taaaagaact tttggctaac gatcctattg ccagggctga atgggaaaaa
    12841 gattttaaac tgaaaaatga tcctcgaatc acagctgtag gtcgatttat acgtaaaact
    12901 agccttgatg agttgccaca actttttaat gtactaaaag gtgatatgag cctggttgga
    12961 ccacgaccta tcgtttcgga tgaactggag cgttattgtg atgatgttga ttattatttg
    13021 atggcaaagc cgggcatgac aggtctatgg caagtgagtg ggcgtaatga tgttgattat
    13081 gacactcgtg tttattttga ttcctggtat gttaaaaact ggacgctttg gaatgatatt
    13141 gccattctgt ttaaaacggt aaaagttgtt tttcaccgca acggtgcgta ttaattttat
    13201 attatatttg gcagagtgtt agtataattg tcatgttcag tttgaggtaa tttatgtact
    13261 aattatctta tattgtaaat catgtgcaat tattttcata tttttatatg aaaaacgtcc
    13321 agtatatata ttgagaaaca ttattgttat ggagacatca tcggagttat gatggaaaaa
    13381 aactcttttc ccataagcca cgaacattcc ttaactatgg attatgttaa agcttttggt
    13441 atgattttcg tattggttgg gcatataaat aatgacatat ttaatgttta ttatgcctat
    13501 cttttccata tgccattatt tttctttatt ggtggggttt tatataaaga tacacggtgt
    13561 ataacaaatt ttacagcgca tgttataaaa aaacagttac cttatcttat agtaacttat
    13621 ttgattattg gttctattgc attattaatt aatgtacgtt atggaataca cacaggtgat
    13681 gctttttcga caggactata tgaaacggtt aaacttgcta taaaatcaaa ttttcataac
    13741 aataaaatgt ttctaacagg ttggtttctg tttgcttata tatttgtgag cattttgtcg
    13801 gtgattataa taaaaagcat aaaacgggtc gttgttagca atgctttatt attatcggta
    13861 ttggtggcga ttagtgtatt attaataact gtctcaataa catatttatc ccctcaatat
    13921 attctggtaa aagactataa gctgaatttt atatgccaag tgttaaccgg tatgtcgttt
    13981 tatatttttg gatacgtgat cagaaatcag atatataact tattaaattt ttatgttttt
    14041 attttattaa ctgtaatatt atatgtttcg aaaagttatg gtttctctac gcagacaatt
    14101 atgtcatgga gttattatcc ggatgggtta ataatgtctg ttattaacgc gctgataggt
    14161 atttatgctg tgttttttat ctctctatta attacaaggg gaatgaaaga aattaagctg
    14221 ctaaaaatga taggtcagaa ttcaagagct atcatggcat atcatttact tgtatatgta
    14281 attttagata taattgcttc aattttaggt gattatagcc tatcgggaac agatgtatat
    14341 gataatcact ttatcactaa atggtccgtt cctgtctaca ttgcattagg tttgctactg
    14401 cctctaattt ttagtattct gaaacagaaa gtaataggga agataaaatt taagcgggat
    14461 tttagaatca attaaaagct aattttagct ttaatgcagc ctaatgttta agtattaatt
    14521 tttggataaa tatcacataa taggttactc aggagatttt tatttagtct accgacgcgt
    14581 tcccagataa ggattccggt gtgtcgtagg tagaaatagg taattaatga ttgtttcttc
    14641 gggctttaag tctgggttat catattattc actttatctc attggatata gttcctatga
    14701 gtaaccacac ctgacaggag tatgtaatgt ccaagcaaca gatcggcgtc gtcggtatgg
    14761 cagtgatggg gcgcaacctc gcgctcaaca tcgaaagccg tggttatacc gtctccgttt
    14821 tcaaccgctc ccgtgaaaag accgaagaag tgattgccga gaatcccggc aaaaagctgg
    14881 tgccttatta cacggtgaaa gagtttgttg aatccctcga aacgcctcgt cgtatcctgt
    14941 taatggtgaa agcgggtgca ggtactgatg cagctatcga ttcgctgaaa ccgtatctgg
    15001 aaaaaggcga tatcattatt gatggcggta acaccttctt ccaggacaca atccgtcgca
    15061 atcgcgagct gtctgcggaa ggttttaact ttatcggtac cga
//
