LOCUS       JX975341               12801 bp    DNA     linear   BCT 27-AUG-2013
DEFINITION  Salmonella enterica strain G1805 O antigen gene cluster, complete
            sequence.
ACCESSION   JX975341
VERSION     JX975341.1
KEYWORDS    .
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12801)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Senchenkova,S.N.,
            Reeves,P.R. and Wang,L.
  TITLE     Structural diversity in Salmonella O antigens and its genetic basis
  JOURNAL   FEMS Microbiol. Rev. (2013) In press
   PUBMED   23848592
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 12801)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Reeves,P.R. and
            Wang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-OCT-2012) TEDA School of Biological Sciences and
            Biotechnology, Nankai University, 23 Hongda Street, TEDA, Tianjin
            300457, P.R. China
COMMENT     ##Assembly-Data-START##
            Sequencing Technology :: Sanger dideoxy sequencing
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..12801
                     /organism="Salmonella enterica"
                     /mol_type="genomic DNA"
                     /strain="G1805"
                     /db_xref="taxon:28901"
                     /note="serogroup: O11"
     misc_feature    1..12801
                     /note="O antigen gene cluster"
     gene            106..1191
                     /gene="rmlB"
     CDS             106..1191
                     /gene="rmlB"
                     /note="RmlB"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase"
                     /protein_id="AFW04815.1"
                     /translation="MKILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLS
                     DISESNRYNFEHADICDSAEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEGARKYWSALGEDKKNSFRFHHISTDEVYGDLPHPDEAENSVTLPLFTETTA
                     YAPSSPYSASKASSDHLVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KPLPIYGKGDQIRDWLYVEDHARALHMVVTEGKAGETYNIGGHNEKKNLDVVFTICDL
                     LDEIVPKATSYREQITYVADRPGHDRRYAIDADKISREIGWKPLETFESGIRKTVEWY
                     LANTQWVNNVKSGAYQSWIEQNYEGRQ"
     gene            1191..2090
                     /gene="rmlD"
     CDS             1191..2090
                     /gene="rmlD"
                     /note="RmlD"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-L-mannose-dehydrogenase"
                     /protein_id="AFW04816.1"
                     /translation="MNILLFGKTGQVGWELQRSLAPVGNLIVLDVHSKEFCGDFSNPK
                     GVAETVRKLRPDVIVNAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGSWVVHY
                     STDYVFPGTGDIPWQETDATSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKERQTLSVINDQYGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAG
                     GTTTWHDYAALVFDEARKAGITLALTELNAVPTSAYPTSASRPGNSRLNTEKFQRNFD
                     LILPQWELGVKRMLTEMFTTTTI"
     gene            2132..3016
                     /gene="rmlA"
     CDS             2132..3016
                     /gene="rmlA"
                     /note="RmlA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="AFW04817.1"
                     /translation="MEMKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLS
                     TLMLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFI
                     GHDDCALVLGDNIFYGHDLPKLMEAAVNKESGATVFAYHVNDPERYGVVEFDQNGTAV
                     SLEEKPLQPKSNYAVTGLYFYDNSVVEMAKNLKPSARGELEITDINRIYMEQGRLSVA
                     MMGRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDAEQIKNLAK
                     PLSKNAYGQYLLNMIKGY"
     gene            3021..3560
                     /gene="rmlC"
     CDS             3021..3560
                     /gene="rmlC"
                     /note="RmlC"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-D-glucose-3,5-epimerase"
                     /protein_id="AFW04818.1"
                     /translation="MNVIKTEIPDVLIFEPKVFSDERGFFMESFNQKVFEEAVGRKIE
                     FVQDNHSKSTKGVLRGLHYQVEPYAQGKLVRCTAGEVFDVAVDIRKDSETFGKWVGVN
                     ISSENKRQLWIPEGFAHGFLVLSDSADFLYKTSNYYSPVHERGIVWNDPTININWPIN
                     IDKILSEKDTILPKFINIA"
     gene            3844..4944
                     /gene="wdaA"
     CDS             3844..4944
                     /gene="wdaA"
                     /note="WdaA"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04819.1"
                     /translation="MYKTLVITTAPVFPTNNGYKSSVLGRLDEMVALRNKVIIIELNF
                     ENSINKNDEVIPERFQRIKRYKIRCNKRTVAHEIKSLLNIKTRHEQLFSDKKIRNRIE
                     DILEIEKPSIIVVESLWALHALPCDVKGKVRCVIHDVAIDFFREMFKSQRGMLRRLCY
                     LNDYVKLQFTEVNILNRVKVDEFLFLTEEDKEWYQDKYNIKQLCSLASNHLYVEKIER
                     KINHKTPFLLIPGSIEFAQIYHGLNWFVKNIYPNLNKKIKVIVTGKASQEKIKRLKVR
                     GEIYFSGELDVIKFNELCSACLGVIAPITTGTGIKIKILEAVQKGIPVVTTKFASKGI
                     DSLLCFYGGDNKDSTFIREINNFLERTLSDSV"
     gene            4941..6020
                     /gene="wzy"
     CDS             4941..6020
                     /gene="wzy"
                     /note="Wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AFW04820.1"
                     /translation="MNILFFLLLSVGLLFSLAYKNKNKNINDSIMFMLVVLMILMSGL
                     RVNDSDYLEYNKMYNEVPSLYNFTLSAIKDIHGEIGYLFLSSFFKTFDLPFQFFLFFI
                     ASLSLMLTYFSFKKASIIPILSLVFYLSHAFIVRDMIQIRAGLAVSMSLYTIVTYKKN
                     RNVITGILLASLIHSGAIIIAICYPFIRKRYLSLKKIFSLFLVALIFSYLHGLDFILN
                     TLIHYNLLPDAVANYIGWEEYDYRINIFTNPVFIKGIMIVFLMRKYIKTNINNENDKV
                     VILYNLYVLGVLAMVGLSEMAILSGRLSSFLTLGESILIVYSVFYKRNISVGFVFFLL
                     LTFIQMGYDLLISNVHPKLSLFIFG"
     gene            6027..7115
                     /gene="wdaB"
     CDS             6027..7115
                     /gene="wdaB"
                     /note="WdaB"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04821.1"
                     /translation="MSKIKVGILISRLQNLGPVNVVRSIVKNSSRFNYTIFCLTDDIN
                     EKISQELLERGVKIIMVPGGNQVSKIYFLKKYIEKNPHDVFHSHGITADVFMFFLNGI
                     KISTIHNRLNEDYLPLFGLLKGNLLYYAHLLLLKSFTHLVACSEAVATKLYQSKITKN
                     VSVIQNGIDINKFHPVSTDKKILLRKKYGFYDIENIYVYCGSLSQRKNVSFLLEHLSL
                     GKNDRFIIIGDGPLFDSCKKSYFIDNRYIFTGKIESPLEYYQLSDFFVSASLSEGLPL
                     ALLEAVSAGCFLYVSDIPPHREVASLLKNNSIEFFSLAGGSNKLKLPLYISKRCDISD
                     EIYFNISDEKMAALYGDLYSSLLTRDLK"
     gene            7112..7894
                     /gene="wdaC"
     CDS             7112..7894
                     /gene="wdaC"
                     /note="WdaC"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04822.1"
                     /translation="MIYISIVSHGHYEIIKKLGTLSNLTKNSFVKIIIKDNLGEKSLE
                     EFCYVNNITYLKNSVKKGFGKNNNEVFNTIAQSIKTDDFFVVMNPDVFIDANVLLEAV
                     YECDKSNAYMATVNLYRDFDKKEYDNSIRKFPCVMDFIHSFLFGKNKCSIDKDGINEP
                     LYVDWAAGSFLIFKAEFFSKLNGFNEKYFMYCEDIDICWRANKIYNTSVLYLPQYVAV
                     HLAQFNNRKILSRHFLWHIKSIVLFLMYKNGFLTINKNDKML"
     gene            7912..9333
                     /gene="manC"
     CDS             7912..9333
                     /gene="manC"
                     /note="ManC"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose pyrophosphorylase"
                     /protein_id="AFW04823.1"
                     /translation="MIPVILAGGTGSRLWPLSRELFPKQFLKLSSELTMLQATFARLN
                     DLNYKNSIVICNEAHRFIVAEQLREIGKLSNNIILEPHGRNTAPAITLAALAVKQRFP
                     DKDPLILILAADHIIKDDRIFCNLIKKAAPLANKGKFVTFGIVPFKPETGYGYIRRGD
                     AVPGATDAVAFEVAQFVEKPGLETAQAYVASGDYYWNSGMFLFRAGRYLEELKKFRPD
                     ILAACEQAMRGVDPDLDFIRVDEEAFLACPEESIDYAVMERTADAVVMPMDAGWSDVG
                     SWSSLWEISAHTPEGNVHHGDVISHKTENSYVYAESGLVTTVGVKDLVVVQTKDAVLI
                     ADRHAVQDVKKVVEKIKADGRHEHHMHREVYRPWGKYDSIDAGERYQVKRITVKPGEG
                     LSVQMHHHRAEHWVVVAGTARVTINGEVKLIGENESIYIPLGATHCLENPGKIPLDLI
                     EVRSGSYLEEDDVVRFEDRYGRV"
     gene            9444..10814
                     /gene="manB"
     CDS             9444..10814
                     /gene="manB"
                     /note="ManB"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="AFW04824.1"
                     /translation="MTKLTCFKAYDIRGRLGEELNEDIAWRIGRAYGDYLKPKTIVLG
                     GDVRLTSESLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPM
                     DYNGMKLVREGARPISGDTGLRDVQRLAEANDFPPVNEAARGSYRQISLRDAYIDHLL
                     GYISVSNLTPLKLVVNSGNGAAGPVIDAVEARLKALGAPVEFIKIHNTPDGTFPNGIP
                     NPLLPECRDDTRKAVIEHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLE
                     KHPGAKIIHDPRLTWNTEAVVTAAGGTPVMSKTGHAFIKERMRLEDAVYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVAELVCLKGQSLGGLVADRMAAFPASGEINSRLAEPAAAIAR
                     VERHFVGEALAVDRTDGLSMSFADWRFNLRSSNTEPVVRLNVESRGDIPLMEARTKEI
                     LQLLNS"
     gene            11100..12626
                     /gene="wzx"
     CDS             11100..12626
                     /gene="wzx"
                     /note="Wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AFW04825.1"
                     /translation="MRTIKAINNFKVDLFITFFLIALGFYLRTIFVSKMGADLTGVML
                     LFTQLTAYLNLAELGIGVAAASLLYKPLSEGDYAKIKYLTLLLSAIYRYISFLVLLIG
                     IVIGFGIYFFIDSVNAVSHVFIYWAFFVINTSLTYSYAKHSTLLTANQQYSVVRKIQG
                     GGKILIIALQIFLLVTTHSFLLYLFVETIGVIVQYFIFKNIINNDIHFKVVSQSISDN
                     EKTALKNELKIKIKNMFFHKIGGVLVLNTDYLLVSKFLNLIYVTIYGSYMMVFQVVTV
                     LMSSFVNAITASVGNFLINQNDDEVTSIAKQFNTVFIALATFISLNMYFLVNDFITNW
                     IGEKFILGNGIIILMLVNVFISVIRIPCDIFKNATGFFGDVYYPLLEGGVNLFFSALL
                     AFYIGLPGIIIGTIISNVLITLIAKPLYLYGKMFGRFNALKKYLSFVLKPLIFSFIIF
                     AVFYFTREQIIFFKVSNWFDFISKLTIVSLVTMITVFAVFYADANFRSFVKRILRVVF
                     "
BASE COUNT     3781 a   2226 c   2833 g   3961 t
ORIGIN
        1 attggtagct gtaagccaag ggcggtagcg tgcgtaacga cttgagcaat taatttttat
       61 tggcaaatta aataccacat taaatacgcc ttatggaata gaaaagtgaa aatacttatt
      121 actggcgggg caggttttat tggatcagct gttgtccgcc atattattaa gaatacacag
      181 gacactgtag ttaatattga taaattaacc tacgccggta atcttgaatc cctttctgat
      241 atttctgaaa gtaatcgcta caattttgaa cacgcggata tttgtgattc cgctgaaata
      301 acgcgtattt ttgagcagta ccagccggac gcggtgatgc atttggctgc ggaaagtcat
      361 gtggaccgtt cgattaccgg gccggcagct tttattgaaa ccaatatcgt cggaacctat
      421 gtacttcttg aaggtgcgcg taaatactgg tctgcgcttg gcgaagataa aaaaaatagt
      481 ttccgttttc atcatatttc aactgatgaa gtttacggcg atttaccgca tcctgatgaa
      541 gctgagaata gcgttacgct gccgttattt actgaaacga cggcatatgc gccaagcagt
      601 ccttactccg cgtcaaaagc atccagcgat catttagtcc gtgcctggag gcgtacttat
      661 ggtctaccaa cgatcgttac caattgttct aataactatg gtccttatca tttccccgaa
      721 aaactgattc cgttggtcat tttgaacgca ctggaaggaa agcctttgcc aatttatggt
      781 aaaggggatc agattcgcga ctggctatat gtagaagatc acgctcgcgc gcttcatatg
      841 gtagtgactg aaggcaaggc aggggagact tataacattg gtggacacaa tgagaagaaa
      901 aatctcgatg tggtatttac catctgtgat cttctggatg agattgtacc caaagcgact
      961 tcttatcgtg aacaaatcac ttatgtcgct gatcgtccgg gccatgatcg tcgttatgct
     1021 attgatgcag ataaaattag tcgcgaaata ggctggaaac cgctggagac ctttgaaagc
     1081 ggtattcgta aaacagtgga atggtacctt gcaaatactc aatgggtaaa caatgttaaa
     1141 agcggggcgt atcagagttg gattgaacag aactatgaag gacgccagta atgaatatct
     1201 tactttttgg taagacaggg caagtaggct gggagttgca acgttctcta gcgccagtgg
     1261 ggaatctgat tgtcctggat gtccattcaa aagagttttg cggtgatttt agcaatccga
     1321 aaggcgttgc cgaaaccgtt cgtaagcttc gtcccgatgt gattgttaac gcagcagcac
     1381 atactgcagt agataaagca gagtctgaac cagaactggc gcagttactt aacgccacca
     1441 gtgtggaagc catcgctaaa gcggccaacg aaactggctc atgggtagtg cattattcaa
     1501 ccgattatgt atttcctggt accggcgata tcccatggca ggaaacggat gctacgtcgc
     1561 cgctgaatgt ctatggcaag accaagctag cgggagaaaa ggccctgcag gataactgcc
     1621 ctaagcacct tatcttccgc accagttggg tttatgcagg taagggcaat aatttcgcaa
     1681 agacaatgct tcgtctggcg aaagagcgtc agacactttc agtcatcaac gatcagtatg
     1741 gcgcgccaac cggtgcggaa ttactggctg actgcacggc gcatgcgatc cgtgtggcgt
     1801 taaataaacc agaagtcgca ggtctttacc atctggttgc cgggggaacc acaacctggc
     1861 atgactacgc ggcgttagtc tttgacgagg cgcgcaaagc agggataacg cttgcgctta
     1921 ctgagcttaa tgctgtgccg accagcgcct acccgacgtc ggcgagcaga cctggaaatt
     1981 cgcgtctcaa tactgaaaag tttcagcgta attttgacct tattctgccg caatgggaat
     2041 taggagttaa gcgtatgctg actgaaatgt ttacgacgac aaccatctga taaatttaaa
     2101 tgcctatcag ggcattttct atgaatgaga aatggaaatg aaaacgcgta agggcattat
     2161 tttagcgggg ggctccggca cccgtcttta tccggtgacc atggcggtaa gtaagcaatt
     2221 gctaccaatt tatgataaac cgatgattta ctatcccctt tccacgctta tgctggcagg
     2281 cattcgagat atcctgatca tcagtacgcc acaggacacg ccgcgttttc aacaactgct
     2341 gggagacggc agtcagtggg ggctgaatct tcaatataaa gtacagccaa gcccggatgg
     2401 cttagcacag gcatttatta ttggtgaaga gttcattggt catgatgatt gtgcattagt
     2461 gctgggtgac aatatcttct atggccatga tttaccaaag ttaatggaag ctgccgttaa
     2521 taaagaaagt ggtgctaccg tctttgctta tcatgtaaac gatccagagc gctacggtgt
     2581 ggttgagttt gaccaaaatg gcacagccgt tagtctggag gaaaaaccgt tacaaccgaa
     2641 gagtaattac gcggtaacgg ggctgtattt ttacgataac agcgtggtgg agatggcgaa
     2701 aaatcttaag ccttctgctc gcggtgagtt agaaatcacg gatattaacc gtatctatat
     2761 ggagcaggga agattgtctg tcgctatgat ggggcgcggt tatgcctggc tggatacagg
     2821 gacgcatcag agtttgatag aggccagtaa ttttattgca actatcgaag aacgccaggg
     2881 actaaaagtg tcctgcccgg aagaaatcgc ttatagaaaa gggtttattg atgcggagca
     2941 gattaaaaat ctggctaaac cgttgtcgaa gaatgcttat gggcagtatc tcctgaacat
     3001 gattaaaggt tattaataaa atgaacgtta ttaaaacaga aattcctgat gtattaattt
     3061 ttgaacctaa agtgtttagt gatgaacgtg ggttctttat ggaaagtttt aatcagaaag
     3121 tatttgagga agcggttggt cgaaagattg aatttgttca ggataatcat tcaaaatcaa
     3181 ctaaaggtgt gttacgtggt ttacattatc aagttgaacc ttatgctcaa gggaagcttg
     3241 tacgctgtac agcaggagaa gtttttgatg ttgctgtaga tattcgcaaa gattccgaaa
     3301 cgtttggtaa atgggttggt gtcaatattt cttctgaaaa caaaaggcag ttgtggatac
     3361 ctgaaggttt tgctcatggg tttcttgttt taagcgatag tgcagatttt ctttataaaa
     3421 cttcgaatta ttactctcct gttcatgaaa gaggtatcgt ttggaacgat ccaacgataa
     3481 acattaattg gccgattaac attgataaaa tcctatcgga aaaagacact attttaccaa
     3541 aatttatcaa tattgcgtaa taagtagaat aataatttaa tttatttttt ttgttaaatt
     3601 attgtgattt tttattaaaa tatgttggaa gattataggc gcaatctatt gtgaaattgc
     3661 tcaattgagt ttcttgtttt aatatataat actatatttt attaagtata tggttgtaat
     3721 attttcaatt cagcaatcac tttttatgag tcattatgac catacctatc aataataata
     3781 agttattcta tatgatgttg gagcaaggtt gattcatctt tattttaaag agatagtata
     3841 tttatgtata aaacacttgt gattactaca gctccagttt ttccaacaaa taatggatat
     3901 aaaagttcgg ttttaggtcg gttggatgaa atggtagcac taagaaataa agttataata
     3961 atagagctaa actttgaaaa tagcatcaac aaaaatgatg aggtaattcc cgaacgcttt
     4021 cagagaatta aacgatacaa aattcgatgt aataagagga cggttgcgca tgaaataaaa
     4081 tcattactta atattaaaac tcgtcatgaa caattatttt cagataaaaa gatccgcaat
     4141 agaatagaag atattcttga aattgaaaag ccatcaataa ttgttgtaga atcattatgg
     4201 gcattacatg ctttaccttg tgatgttaag gggaaagttc gttgtgttat acatgatgta
     4261 gctattgatt tttttagaga aatgtttaaa tcccaaagag gaatgctaag gagattgtgt
     4321 tatcttaatg attatgttaa attgcaattt acagaagtta atattttaaa tcgtgtaaaa
     4381 gttgatgaat tccttttttt aactgaagaa gataaagagt ggtaccaaga taaatataac
     4441 atcaagcaac tttgttctct cgcctctaat catctatatg ttgaaaaaat tgaaagaaaa
     4501 ataaatcata agactccatt tctattaatt ccaggaagta tagaatttgc tcaaatttat
     4561 catggactaa actggtttgt taaaaatata tatcctaatc ttaataaaaa aataaaagta
     4621 atagtaacag gtaaagcatc tcaagaaaaa ataaagaggt taaaggttag gggggaaata
     4681 tatttttctg gggagttgga tgttattaaa tttaacgaac tttgttctgc atgtttaggt
     4741 gttattgctc ctataacaac gggtacaggg attaaaatta agattcttga ggccgtgcaa
     4801 aaaggaatcc ctgtagtaac aaccaagttt gcatcaaagg gaatcgactc tttattatgt
     4861 ttttatgggg gcgataataa ggattcaaca tttataagag aaattaataa ctttttagag
     4921 cgtacactaa gtgattcagt atgaatatat tatttttttt gcttctaagt gttgggttat
     4981 tattttccct cgcatataaa aataaaaata aaaatataaa tgatagtatc atgtttatgc
     5041 ttgtcgtcct gatgatatta atgtcaggcc ttagagttaa tgatagtgat tatcttgagt
     5101 ataataaaat gtataatgaa gttccttcat tatacaattt tacgttatct gcgataaaag
     5161 atattcatgg agagattggc tatcttttcc tttcatcttt ttttaaaaca tttgatttac
     5221 cgtttcagtt ttttttattc tttatagcat cgttatcttt gatgcttact tatttttctt
     5281 ttaaaaaagc aagtattata ccaatattat ctctagtttt ttatttaagt catgctttta
     5341 ttgttaggga tatgatacaa ataagagctg gattagcggt gagtatgtct ctatacacaa
     5401 ttgtgacata taagaaaaat cgaaatgtga tcacagggat actgcttgca tcgctgattc
     5461 attctggagc aattataatt gctatttgct acccatttat aagaaaaaga tatttatcgt
     5521 taaaaaaaat attttctctt ttcttggttg ccttaatatt ttcttattta catgggctcg
     5581 actttatatt aaacaccctt attcattata atcttctgcc agatgctgtt gcaaattata
     5641 ttgggtggga agaatatgat tatagaatta atattttcac taatccagta tttattaaag
     5701 ggataatgat agttttttta atgagaaaat atattaaaac aaatataaat aatgaaaatg
     5761 ataaggtggt tatattatat aatttatatg ttttaggtgt tttagcaatg gttgggttaa
     5821 gtgagatggc tatactttca ggacgtcttt catcgttttt aacactaggt gaaagcatat
     5881 taatagtata tagtgttttt tataaaagaa atatctcggt aggttttgtt ttctttttgt
     5941 tattaacttt catacagatg ggatatgatc tgttaatttc aaacgtacat ccgaagctct
     6001 ctctttttat atttggataa agtgaagtgt caaaaattaa agtaggaatc ctaatttcga
     6061 gactccagaa tcttggacct gtaaatgtag ttcgtagtat agttaagaat agttctcgtt
     6121 ttaattatac tattttttgt ttaacagatg atataaatga aaaaatttca caagaattat
     6181 tagagcgtgg cgttaagatt ataatggttc cgggtggcaa ccaagttagt aaaatttatt
     6241 ttttaaaaaa atatatagaa aaaaatccac atgatgtttt tcattcacat ggtattacag
     6301 cagatgtttt tatgtttttt ttaaacggca taaaaatatc aactatccat aatagattga
     6361 atgaggatta cttaccgctt tttggtctcc tcaaaggcaa tttgttatat tacgcacatt
     6421 tgttgttatt gaagagtttt actcatttag ttgcatgctc agaagcggtt gctacaaaac
     6481 tataccaatc aaaaataaca aaaaatgttt ctgtaatcca aaatggaatt gatattaata
     6541 aattccatcc cgtttcgaca gataaaaaaa tcttactaag aaaaaagtat ggtttctatg
     6601 atatagaaaa tatatacgta tattgtggtt ccttatctca aagaaagaat gtatccttcc
     6661 ttttagaaca tttatcttta ggtaagaatg atagatttat tattattggc gatggtccat
     6721 tatttgactc ttgtaaaaag agttatttta tagacaatag atatattttt acaggaaaaa
     6781 ttgagtcacc tttagaatac tatcagttat ctgatttttt tgtttcagct tctttatctg
     6841 aaggtcttcc cttggcattg ttggaggcag tctctgctgg ttgcttttta tatgtaagtg
     6901 atattccccc gcatagggaa gttgcaagct tattaaaaaa taactcaatt gaatttttta
     6961 gtttggcagg agggagtaat aaattgaaac tgccgttata tatatcaaag agatgtgata
     7021 taagtgatga aatttatttc aatatttctg atgaaaaaat ggctgcatta tatggcgact
     7081 tgtattcttc cttattaaca agggatttaa aatgatatat atatcgatag tctcgcatgg
     7141 gcattatgag attataaaga aattagggac attatcaaat ttaactaaaa atagctttgt
     7201 taaaattatt ataaaagata acttaggtga aaaaagtttg gaagagtttt gctatgtcaa
     7261 taacataact tatttaaaaa acagtgttaa aaaaggattt ggtaaaaata ataatgaagt
     7321 ttttaatacc atagcgcaga gtataaagac ggatgatttt ttcgtagtga tgaatcctga
     7381 tgtttttata gatgctaatg tattgctgga ggctgtttat gaatgcgata agtctaatgc
     7441 atacatggcc acagtcaatc tatatagaga ttttgataaa aaggaatatg ataattccat
     7501 tagaaaattc ccttgtgtaa tggattttat ccattcattt ttatttggaa aaaataaatg
     7561 ttcaattgat aaagatggga taaatgaacc tttatatgtt gattgggcag caggttcttt
     7621 tcttatattt aaagctgaat ttttctctaa gctaaatgga tttaatgaaa aatactttat
     7681 gtattgtgag gatatagaca tatgttggcg agcaaataaa atttacaaca cttcggtttt
     7741 gtatttaccc cagtatgttg ctgttcattt ggctcaattt aataatcgta aaatattatc
     7801 tcgtcatttt ttatggcata taaaaagcat tgtattattt ttaatgtata aaaacggatt
     7861 cttaacgata aataaaaatg acaagatgct ttaaagaata taggtgtgta tatgattcca
     7921 gtaattttag ctggtgggac tggtagtcga ctctggcctc tttcaagaga gctttttcca
     7981 aaacaatttt taaaattgtc tagcgaacta acaatgctac aagctacttt tgctcgcctc
     8041 aatgacttaa attataaaaa ctctatcgta atatgcaatg aagcacatag atttattgta
     8101 gcagagcaat taagagaaat tggaaagctt tctaataata ttatccttga gcctcatggg
     8161 cgtaacacag cccctgctat tactcttgca gcattggcgg ttaaacaacg ttttcctgat
     8221 aaagaccctt tgattttaat tctagccgct gaccatatta ttaaggatga caggattttc
     8281 tgtaatctta taaaaaaagc tgctccttta gctaataagg gcaaatttgt tacttttggg
     8341 atagttccct ttaaaccgga aaccggctat ggctatatcc ggcgcggcga tgccgtaccg
     8401 ggcgcgacgg atgcggtggc ttttgaggtg gcgcagttcg ttgagaagcc ggggctggaa
     8461 accgcccagg cctacgtcgc cagcggcgat tactactgga acagcggcat gtttctgttc
     8521 cgcgccgggc gctatctgga agagctgaaa aagttccgcc ccgatattct ggccgcctgt
     8581 gaacaggcga tgcgcggtgt cgatccggat cttgacttca ttcgcgtgga tgaagaggcc
     8641 ttccttgcct gtccggaaga gtccatagac tatgccgtga tggagcggac agcggacgcg
     8701 gtggtgatgc caatggacgc gggctggagc gatgtcggct cgtggtcctc gctgtgggaa
     8761 atcagcgccc acaccccgga gggaaacgtc caccacggcg acgtcatcag ccataaaacg
     8821 gaaaacagct acgtttacgc cgaatccggc ctggtgacca ccgtcggcgt gaaggatctg
     8881 gtggtggtac agaccaaaga cgcggtgctg attgccgatc gccacgcggt gcaggacgtc
     8941 aaaaaggtgg tggaaaagat caaggccgac ggacgccatg agcaccacat gcaccgcgag
     9001 gtttaccgtc cgtggggcaa atacgactcc atcgatgcgg gcgagcgcta tcaggtgaaa
     9061 cgtattaccg tcaagccggg ggaagggctg tcggtgcaga tgcatcatca ccgcgccgag
     9121 cactgggtgg tggtggcggg gaccgccaga gtcaccatca acggcgaggt taagctgatc
     9181 ggtgaaaacg agtccatcta tataccgctg ggggcgaccc actgcctgga aaatccggga
     9241 aaaataccgc tcgatttaat tgaagtgcgt tccggctcgt atctcgaaga ggacgacgtg
     9301 gtgcggttcg aggaccgtta cgggcgggtc tgacgcctta aattgtgtcc ggtaagcgca
     9361 acgcgtcgtc cggcaatgaa caacactaac gattcaggcc atttacggtc agggctaact
     9421 gttgcctgaa gaagggtaaa aacatgacaa aattaacctg tttcaaggcc tacgacattc
     9481 gcggcaggct gggcgaagag ctcaatgaag atatcgcgtg gcggattggc cgcgcctatg
     9541 gcgactattt aaaaccgaaa accatcgtgc tgggcggcga cgtgcggctc accagcgagt
     9601 ccctgaagct ggcgctggcg aaagggctac aggatgcggg cgtcgacgta ctggatatcg
     9661 gcatgtccgg caccgaagag atttacttcg ccaccttcca cctcggcgtg gacggcggca
     9721 tcgaagtgac cgccagccat aacccgatgg actacaacgg catgaagctg gtgcgcgagg
     9781 gcgcccgccc gataagtggc gacaccggcc tgcgcgatgt ccagcgtctg gcggaggcca
     9841 acgacttccc gccggtgaac gaggccgcgc gcggcagcta cagacaaatc agcctgcgcg
     9901 acgcctacat cgaccacctg ctcggctata tcagcgtcag caatctcacc ccgctgaagc
     9961 tggtggtgaa ttccggcaat ggggcggcgg ggccggtcat tgacgccgtc gaagcgcgtc
    10021 tgaaggcgct gggcgcgccg gtggagttca tcaaaatcca caacaccccg gacggcacct
    10081 tcccgaacgg cattcccaat ccgctgctgc cggagtgccg cgacgacacc cgcaaggccg
    10141 ttattgaaca cggggcggac atgggcatcg cctttgacgg cgacttcgac cgctgcttcc
    10201 tgtttgatga gaaagggcag tttatcgagg ggtactacat cgtcggcctg ctggcggaag
    10261 cgtttctgga aaaacacccg ggggcgaaga ttattcacga tccgcgcctg acctggaaca
    10321 ccgaggcggt ggtgacggcg gcgggcggga cgccggtgat gtcaaaaacc gggcacgcct
    10381 ttatcaagga gcggatgcgt cttgaggatg cggtgtacgg cggcgagatg agcgcgcatc
    10441 actattttcg tgattttgcc tactgcgaca gcgggatgat cccgtggctg ctggtggcgg
    10501 agctggtgtg cctgaagggg cagtcgctgg gcgggctggt ggcggaccgg atggcggcgt
    10561 tcccggcgag cggggaaatc aacagcaggc tggcggagcc ggcggcggcg attgcccggg
    10621 tggagcggca ttttgtcggt gaggcgctgg cggtggaccg tactgacggc ctcagcatgt
    10681 cgttcgctga ctggcgcttc aacctgcgct cgtcgaacac cgaaccggtg gtacgcctga
    10741 atgtggaatc acgcggcgat ataccgctga tggaagcgcg aacgaaagaa attcttcagc
    10801 tactcaattc ataaaaagca gcccttcttt atggagggct aacttttcgg atattctcta
    10861 accaattcgt agtataaagc taataaatat taagtgtgtt tgattaatgt tggtttccat
    10921 ttctaataaa tataaggttt tcgctatgtt cttttcggat agtataaata atcattgata
    10981 tgattattta ttttaccttc ttggtaatat taattattat ggggttaata ataattgatg
    11041 taatcctgta acctcccacg aatatttatt tactttaagt ttacatccgg aaagtaaaaa
    11101 tgcgaactat aaaagcgatt aacaacttta aagttgattt atttattact ttttttctta
    11161 ttgcgctagg gttttatctt cgaactatat ttgtctctaa gatgggcgct gacttaactg
    11221 gtgtgatgtt gttatttaca caactgactg cttatttaaa tctcgccgag cttggcatag
    11281 gggtagctgc ggcaagcctt ttatacaagc cgctgagtga gggggattat gcaaaaataa
    11341 aatacttaac tttattgctg tctgcaatct atagatatat ctcgttttta gttttattga
    11401 taggtatagt aattggcttt ggtatctact ttttcatcga ttctgttaat gcagtaagtc
    11461 acgtttttat ttattgggca ttttttgtaa taaatacatc tttaacttat tcttatgcaa
    11521 agcattcaac tctattaact gcaaatcagc aatattcagt cgtccgtaaa atacagggtg
    11581 gcgggaaaat attaattatt gcgctgcaaa tatttctatt agtcaccaca catagtttct
    11641 tactctattt gttcgttgaa actattggtg tgatagtaca gtattttata tttaaaaata
    11701 ttattaataa cgacatccat tttaaggtag tttcacaatc tattagcgat aatgaaaaaa
    11761 cagcattaaa aaatgaatta aaaataaaaa taaaaaacat gttttttcat aagattggtg
    11821 gtgtgttggt tttaaatact gattatttgc tagtttcaaa atttcttaat ttaatctacg
    11881 tcacgattta tggaagttat atgatggtct tccaagttgt gactgtactt atgtccagtt
    11941 ttgttaatgc tattacagct agtgtgggta attttttaat caatcaaaat gatgatgaag
    12001 ttaccagtat tgcaaagcaa tttaacacag tatttatagc gttggctacc ttcatttctt
    12061 tgaatatgta ttttttggtt aatgatttca ttaccaactg gataggcgaa aaattcatat
    12121 tgggtaatgg tattattata ttgatgcttg ttaatgtatt tataagtgtc attagaattc
    12181 cttgtgatat ttttaaaaac gcaactggtt tttttgggga tgtatattat cctttgcttg
    12241 agggaggggt taatttattt ttttccgcgc tcctggcttt ttatattggt cttcccggta
    12301 ttattattgg cacgattata tccaatgtat taattacatt aattgcaaag ccattatatc
    12361 tatatggtaa aatgtttggt agatttaatg cattaaaaaa gtacttgtcc tttgtactga
    12421 aacctttaat attctcattt attatttttg cggtttttta ttttacaaga gaacaaataa
    12481 ttttctttaa agtttccaac tggtttgact ttataagtaa gcttactatt gtatcgctgg
    12541 taactatgat tacagttttt gcggtttttt atgcagatgc caactttagg tcttttgtta
    12601 aaagaatttt acgcgtggta ttttaagtta accaggcggg aaaatatccg ccgaaccata
    12661 atgtgctatt aatggacagg tatttaatat gctttacgct gtaaaatttg tagcacataa
    12721 tggtgaaata tatgtaactt ccacacctga caggagtatg taatgtccaa gcaacagatc
    12781 ggcgtcgtcg gtatggcagt g
//
