LOCUS       AY730593               14323 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Salmonella enterica subsp. enterica serovar Urbana UDP-glucose
            pyrophosphorylase (galF) gene, partial cds; O-antigen gene cluster,
            complete sequence; and 6-phosphogluconate dehydrogenase (gnd) gene,
            partial cds.
ACCESSION   AY730593 AY012194
VERSION     AY730593.1
KEYWORDS    .
SOURCE      Salmonella enterica subsp. enterica serovar Urbana
  ORGANISM  Salmonella enterica subsp. enterica serovar Urbana
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14323)
  AUTHORS   Jensen,S.O. and Reeves,P.R.
  TITLE     Molecular evolution of the GDP-mannose pathway genes (manB and
            manC) in Salmonella enterica
  JOURNAL   Microbiology (Reading, Engl.) 147 (PT 3), 599-610 (2001)
   PUBMED   11238967
REFERENCE   2  (bases 1 to 14323)
  AUTHORS   Samuel,G., Hogbin,J.P., Wang,L. and Reeves,P.R.
  TITLE     Relationships of the Escherichia coli O157, O111, and O55 O-antigen
            gene clusters with those of Salmonella enterica and Citrobacter
            freundii, which express identical O antigens
  JOURNAL   J. Bacteriol. 186 (19), 6536-6543 (2004)
   PUBMED   15375135
REFERENCE   3  (bases 1 to 14323)
  AUTHORS   Jenkins,S.O.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2000) School of Molecular and Microbial
            Biosciences, University of Sydney, Sydney, NSW 2006, Australia
REFERENCE   4  (bases 1 to 14323)
  AUTHORS   Reeves,P.R., Samuel,G., Hogbin,J.-P. and Wang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2004) School of Molecular and Microbial
            Biosciences, University of Sydney, Sydney, NSW 2006, Australia
  REMARK    Sequence update by submitter
COMMENT     On Oct 25, 2004 this sequence version replaced AY012194.1.
FEATURES             Location/Qualifiers
     source          1..14323
                     /organism="Salmonella enterica subsp. enterica serovar
                     Urbana"
                     /mol_type="genomic DNA"
                     /strain="M284"
                     /serotype="30"
                     /serovar="Urbana"
                     /sub_species="enterica"
                     /db_xref="taxon:260677"
     gene            <1..852
                     /gene="galF"
     CDS             <1..852
                     /gene="galF"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose pyrophosphorylase"
                     /protein_id="AAV34505.1"
                     /translation="MHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEIVLVTHA
                     SKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNVRQAQPLGLGHSILC
                     ARPVVGDNPFIVVLPDIIIDDATADPLRYNLAAMVARFNETGRSQVLAKRMKGDLSEY
                     SVIQTKEPLDNEGKVSRIVEFIEKPDQPQTLDSDLMAVGRYVLSADIWAELERTEPGA
                     WGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYGLRNLKEGAKFRKS
                     IEQLLHE"
     gene            1220..2002
                     /gene="wbdN"
     CDS             1220..2002
                     /gene="wbdN"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AAV34506.1"
                     /translation="MNREIVSVIMPVYNGSHTIVDSIESVLNQTYKDIKLYVIDDCST
                     DDTAKLLTVNYANNKNVKIIISSKNKGVAASRNLGIKESKGKYIAFCDADDLWENNKI
                     EKQINLLEHNNINVVCSNYYIMDFNKKIIGETHSPVTISYKKMLMKNYVGNLTGVYNA
                     EKLGKFYQKKVGHEDYLMWLEIIKKSNFAICLQENLAFYRVSNNSLSASKLVAAKWTW
                     NIYRECLGLSLPKSLYYFSLYAANGVIKKIGLINSDNSKAKE"
     gene            2255..3157
                     /gene="wzy"
     CDS             2255..3157
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AAV34507.1"
                     /translation="MEIMAIILFAKEGIPIFDADPGGAKLKIADGNGIYIRYIKYFGN
                     IVTFTLLLLLNKQKVKQKIIAIIYFLTIALFGYRSELVLLFLQYYIIMSIVNEGGNKY
                     KFLNKIFIFIFMGGVIGSLFYFSLGQDGAVNNSTENIDRIINRLTIEQVESVPYIISE
                     SLEYDLFPTPELGKEINAIFNRILGEKDQNLFYGERLHKKVFGDMGANFLSVTTYGAE
                     LLAFFGPLCIFLIPIGLCIPFAMLKKISNTHSTVNGAIYSFLIMILLQYLIAGNASAF
                     FFGPFITAIVMSIPLMILHDILKR"
     gene            3163..3894
                     /gene="wbdO"
     CDS             3163..3894
                     /gene="wbdO"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AAV34508.1"
                     /translation="MNTSVITVTYNNAEGLNKTLESLCLLKVKPYEIIIIDANSIDNT
                     KAIVKKYSDMNIIYICEKDNGIYDAMNKGLRLARGKLLHYLNAGDCVSGEIYADLNGP
                     CLLKVGLFDKDNLIGFSSLTHSNTGYCHQGIIFPSKHPIYDLKYKLCADYKLIQMVFP
                     MGLKQLPLISNGFIKYDMGGVSANKRFLRDKELLQIMLETNKKTLIKFIPLMVIKMVF
                     PKKIRRILRRVNYYFSLILTNKKNV"
     gene            3896..5287
                     /gene="wzx"
     CDS             3896..5287
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AAV34509.1"
                     /translation="MIKEKIKILFKYCTLRKYNTTTDYGRQQERYRIISLSIISNFIS
                     KLLALLSLILTVSLTLPYLGQDRFGIWMTIASFSAALTFLDLGIGNALTNRIAHSFAR
                     GKKIRMIRQISGGLTLLAILAFIIIAIFLTIANFVNWGSLLKGINDNTHDEVQFAIKL
                     FAIIFGIGIFSNGVQRIYMGMQKAYISYISNAFFILISIISLFISSRLHAGIPMLILS
                     TIGVQYLSGLSLTILLIYKKLITLNKIRINVKKETPYLISNGFFFFILQMGTLATWSG
                     DNFIISTTLGVTYVSILSITQRLFQISTVPLTIYNAPLWAAYADAHARHDVDFIRKTL
                     LGSLKIVGISSTTLALILVIFGQSIIAIWTGEELRVPQSLIVAYAVWSIIDAYSNTLS
                     SFLNGLNIIKQQVFAVVTLILISIPSKYFIVSHFGLTAMLSCFIILYVTNYLIWYKCS
                     FKKSIHLQLNIRG"
     gene            5290..6384
                     /gene="per"
     CDS             5290..6384
                     /gene="per"
                     /codon_start=1
                     /transl_table=11
                     /product="perosamine synthetase"
                     /protein_id="AAV34510.1"
                     /translation="MEYIPVYQPALSGKEKEYVNDCIDSTWISSKGSYIQRFEKKFAE
                     QNNIQYATTVSNGTVALHLALLALGISEGDEVIVPTLTYIASVNAIKYTGATPVFVDS
                     DLQTWQISVDDIKNKITSRTKAIMCVHLYGHPCDMSPILEIAKVNNLFIIEDCAEAFG
                     SKYKDKFVGTFGDISTFSFFGNKTITTGEGGMVVTNDKTLYDRCLHFKGQGLAAHRQY
                     WHDVIGYNYRMTNICAAIGLAQLEQAQLFIARKREIAEIYKNNLTPLIEVHQEGNDIF
                     HTYWMVSILARNAEEREVLRSFLSEKLTETRPLFYPVHTMPMYSDKYQKHPVAENLGW
                     RGINLPSFPTLSNEQVIYICNAINEFYKDK"
     gene            6409..7623
                     /gene="wbdP"
     CDS             6409..7623
                     /gene="wbdP"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AAV34511.1"
                     /translation="MKITLNTDGFNEWGGGVDFIKYLLRTLEIEQDIFLDVLLPREDI
                     SSLLKRNIFPVKNMIKAILSGQTPRWKKLEGFNEQYYKHAFAEITEQSKLSFITGKSS
                     AYFSHYIKSDYDIILPCMRTPAVNMKNRAWLGYIYDFQHCYYPSFFSEREIAKRNLFF
                     KRMLDNANNVIVNSHAVISDAKKFVGDFSANLHALPFSPCPELNWLNDNSDLIDKYAI
                     DKDYFIICNQFWKHKDHSTAFKAFKKYIEINPDVYLVCTGATQDYRFPGYFDELMCLL
                     KKLGISEKVKILGHIPKLEQIELIKNSIAVIQPTLFEGGPGGGITFDAVALGKKIVLS
                     DIEVNKDVDCGHVYFFHSQNEYSLTEALVKATAVDHYYDPHVLLESGIKRRKKCADFI
                     LNVISKEIESRI"
     gene            7647..8765
                     /gene="gmd"
     CDS             7647..8765
                     /gene="gmd"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose dehydratase"
                     /protein_id="AAV34512.1"
                     /translation="MSKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERV
                     DHIYQDPHSCNPKFHLHYGDLTDASNLTRILQEVQPDEVYNLGAMSHVAVSFESPEYT
                     ADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVA
                     KLYAYWITVNYRESYGIYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYL
                     GNMDSLRDWGHAKDYVRMQWMMLQQEQPEDFVIATGVQYSVRQFVELAAAQLGIKLRF
                     EGEGINEKGIVVSVTGHDAPGVKPGDVIVAVDPRYFRPAEVETLLGDPSKAHEKLGWK
                     PEITLSEMVSEMVANDLEAAKKHSLLKSHGFNVNLSLE"
     gene            8768..9733
                     /gene="fcl"
     CDS             8768..9733
                     /gene="fcl"
                     /codon_start=1
                     /transl_table=11
                     /product="fucose synthetase"
                     /protein_id="AAV34513.1"
                     /translation="MNKQRIFVAGHRGMVGSAIVRQLAQRGDVELVLRTRDELDLLDG
                     RAVQAFFAGTGIDQVYLAAAKVGGIVANNTYPADFIYENMMIESNIIHAAHLHNVNKL
                     LFLGSSCIYPKLARQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRS
                     VMPTNLYGPHDNFHPDNSHVIPALLRRFHEAAQSHAPEVVVWGSGTPMREFLHVDDMA
                     AASIHVMELSREVWQENTAPMLSHINVGTGVDCTISELAQTIAKVVGYQGRVVFDAAK
                     PDGTPRKLLDVTRLHQLGWYHEISLEAGLAGTYQWFLENQQRFRG"
     gene            9736..10236
                     /gene="gmm"
     CDS             9736..10236
                     /gene="gmm"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose mannosylhydrolase"
                     /protein_id="AAV34514.1"
                     /translation="MFLRQEDFAAVVRATPLISLDFIVENGQGEILLGQRLNRPAQGY
                     WFVPGGRVRKDETLEAAFARLTQAELGVRLPLAAGTFYGVWQHFYDDNFSGEDFSTHY
                     IVLGFRLRVAESDLLLPDAQHGSYRWLTPEQLLASDNVHDNSRAYFQNAPYSVIGLDK
                     KDVKYV"
     gene            10229..11677
                     /gene="manC"
     CDS             10229..11677
                     /gene="manC"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-P guanosyltransferase"
                     /protein_id="AAG41693.2"
                     /translation="MSDVSLIAVVMAGGTGSRLWPLSRELYPKQFLQLSGEHSLLQTT
                     LLRLSALACKDPLVITNEQHRFIVAEQLRQIDQLHDNIILEPCGRNTAPAIALAAFSA
                     LKRNEQEDPLLLVLAADHVIAKENVFCNAIKKAVPIAENGNIVTFGIIPEYAETGYGY
                     IERGAPFSVNGNSTGIDFYHVKNFVEKPERLTAEKYISAGNYFWNSGMFMFKASVYLN
                     ELKKFRPDIYSICEQVVSSSYRDLDFIRIPEALFKDCPAESVDFAVMEKTEHCIVCPI
                     NIGWSDVGSWQSLWDISEKTNEGDVCKGDILTYNTKNNYIYSESALVAAVGVEDIVIV
                     QTKDAILVSKKSDVQDVKKIVEMLKTQDRTEYISHREVFRPWGKFDSIDQGERYRVKK
                     IVVKPGEGLSLRMHHHRSEHWIVLSGTAKVTLDDKTMLVTANESIYIPLGATYSLENP
                     GVIPLNLIEVSSGDYLGEDDIVRQKERYRKDD"
     gene            11681..13051
                     /gene="manB"
     CDS             11681..13051
                     /gene="manB"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="AAG41694.2"
                     /translation="MNKLTCFKAYDIRGRLGEELNEDIAWRIGRAYGEYLKPKTIVLG
                     GDVRLTSEALKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPM
                     DYNGMKLVREGARPISGDTGLRDVQRLAEAGNFPPVNEAARGSYRQISLRDAYIGHLL
                     GYISVSNLTPLKLVVNSGNGAAGPVIDAIEARLKALGAPVEFIKIHNTPDGTFPNGIP
                     NPLLPECRDDTRKAVIEHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLE
                     KHPGAKIIHDPRLTWNTEAVVTAAGGTPVMSKTGHAFIKERMRTEDAIYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVAELVCLKGQSLGELVRDRMAAFPASGEINSRLAEPAAAIAR
                     VEAHFAEEAQAVDRTDGLSMSFANWRFNLRSSNTEPVVRLNVESKANTELMEEKTQAI
                     LTLLRK"
     gene            13223..>14323
                     /gene="gnd"
     CDS             13223..>14323
                     /gene="gnd"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="AAV34515.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLEKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKDAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELANT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKAQRVAASKVLSGPKAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYHWDLNYGEIAKIFRAGCIIR"
BASE COUNT     4175 a   2738 c   3351 g   4059 t
ORIGIN
        1 atgcacatgt tgcctgcaac caaggcaatc ccaaaagaga tgctaccgat cgtcgacaag
       61 ccaatgattc agtacattgt cgatgagatt gtggctgcag ggatcaaaga aatcgtactg
      121 gtgactcacg catctaaaaa cgccgttgag aaccacttcg acacctctta tgaacttgaa
      181 tcacttcttg agcagcgcgt taagcgtcag cttttggcgg aagtgcaatc tatctgccca
      241 ccgggcgtga cgattatgaa cgttcgccag gcgcagccgt tagggctggg gcattctatt
      301 ctgtgcgcgc gtccggtcgt gggcgataac cctttcattg tggtactccc ggatattatt
      361 attgatgatg ctaccgccga tccgctgcgc tataaccttg cggcgatggt ggcgcgtttc
      421 aatgaaacgg gtcgcagcca ggtgctggcg aagcgcatga aaggtgattt atcggagtat
      481 tccgttatcc agacgaaaga acctctggat aatgaaggca aagtcagccg gattgtggag
      541 tttatcgaaa aaccggatca gccgcagacg ctggattctg atttgatggc ggtaggccgt
      601 tatgtgcttt cagccgacat ctgggcggaa ctggaaagaa ccgaaccggg cgcctggggc
      661 cgtatccagc tcaccgatgc cattgctgag ctggcaaaaa aacagtcggt tgacgcgatg
      721 ctaatgacgg gtgacagcta tgactgcggt aaaaaaatgg gctacatgca ggcatttgta
      781 aagtacgggc tgcgcaacct gaaagaagga gcgaagttcc gtaagagcat agagcagctt
      841 ttgcatgaat aagtattaac aaccgtgata aatggttggt gataaacata ataacggcag
      901 tgaacattcg aagcggcaag ttggctgaaa cgagtgttga ctgccgtttt agttttgtat
      961 aaagggctta agtaacaagg ggttatctgg agcattttaa tgctgatttt ataagattta
     1021 tccttgtttc taacggcaat tgataagaca attggcgttt aagttttagt gagctttgcc
     1081 ctgtatgggc gaggtttgta acaagtcggt atgtacgcag tgcactggta gctgatgagc
     1141 caggggcggt agcgtgcaag taaaattacc cgtatgaaat tataatttca cctttgagaa
     1201 acactgataa cacattaaga tgaatagaga aattgtttca gtaattatgc ctgtatataa
     1261 cggttcccac actattgttg actctataga atcagtttta aatcaaacct acaaagatat
     1321 aaagttatac gttatcgatg attgtagtac agatgacact gctaagttat tgaccgtaaa
     1381 ttatgctaac aataaaaatg taaagattat aataagttca aaaaataaag gggtcgctgc
     1441 aagtagaaac ttaggaatta aggaatccaa aggaaagtat attgcatttt gtgacgctga
     1501 tgatctttgg gaaaataaca aaattgaaaa gcaaattaat ttattagagc ataataatat
     1561 taatgttgtt tgttccaact actacattat ggattttaat aaaaaaataa ttggtgaaac
     1621 ccatagtcca gtcactataa gttataaaaa aatgcttatg aaaaactacg ttggaaatct
     1681 aacaggtgtg tataatgcag aaaaattggg taaattttat caaaaaaaag taggtcatga
     1741 agattatctt atgtggctgg aaattataaa aaagagcaat tttgctattt gtctacaaga
     1801 aaatcttgcc ttttatagag tttcgaacaa ttctttatcc gcaagtaaat tagttgcagc
     1861 gaaatggaca tggaatattt acagagaatg tttagggtta tccctcccga aatctttata
     1921 ttatttctct ttatatgcag ctaatggagt aataaaaaaa attggcctta taaattcaga
     1981 taactcaaaa gcgaaggagt aaggattgaa cagatctgtt aaactggttt gtctctttct
     2041 actatcattc tatgctcttc agttatttgg aatagcaaca gatataagga ttaaagatga
     2101 caatataaga atcattacta gttctcttat cctataccaa gttattttta tcttattatt
     2161 ttttataata tataggaaaa aaagacaaga acaaacacaa tatttcatta taaacactaa
     2221 aattaaagta gtattctttt tactttttat aaccgtggaa attatggcta taattctctt
     2281 tgccaaagag ggaataccta tttttgatgc ggaccctgga ggggcaaagc ttaaaattgc
     2341 ggatggcaat ggaatatata taagatatat aaaatatttt ggtaatatag taaccttcac
     2401 tttattgtta ctcctaaata aacaaaaagt aaaacaaaaa ataatagcaa taatatattt
     2461 cttaacaatt gctctatttg gctatcgatc agagttggta ctgttattcc ttcaatatta
     2521 tataattatg tcaattgtta atgaaggggg taataaatat aaatttttaa ataagatttt
     2581 catttttatt tttatggggg gagtcattgg tagtttattt tattttagtt taggacagga
     2641 tggtgcggta aataatagta ctgaaaatat tgatagaatc attaatagac taactattga
     2701 gcaagttgaa agtgttccat atattatttc tgagtcctta gaatacgacc tattcccaac
     2761 accagagttg ggtaaagaaa taaacgctat ctttaataga attttaggag agaaagacca
     2821 aaatttattt tatggcgaac gactacataa aaaagttttt ggagatatgg gggctaattt
     2881 tttatcagtc actacatatg gagcagaact tttggctttt tttgggcctt tatgcatatt
     2941 tttaattccc ataggattat gtataccttt tgcaatgttg aaaaaaatat caaatacaca
     3001 tagcactgtt aatggtgcta tatattcatt tttaattatg attttattac aatatttaat
     3061 tgctggaaat gcatctgctt tcttttttgg tccatttatt acagcaattg taatgagtat
     3121 accattgatg atactacatg acatattaaa gagataatag ttatgaatac atctgttata
     3181 acagtgacat acaataatgc agaaggacta aataaaacac ttgagagttt atgcttactc
     3241 aaagttaaac cttatgaaat aattattatc gatgcaaatt ctattgataa tactaaggct
     3301 atagtaaaaa aatattcgga tatgaatatc atatatattt gcgaaaagga taatggaata
     3361 tatgatgcaa tgaataaagg cctcagacta gcacgtggta agttattaca ttatttaaat
     3421 gctggtgact gtgtaagtgg agaaatttat gccgatttaa atggtccttg tttactaaaa
     3481 gtaggtctgt tcgataaaga taatttaatt ggattttcct ccttaacaca ttcaaatact
     3541 ggatattgtc accaaggtat aatttttccg agtaaacatc ctatctatga tttaaaatat
     3601 aaactatgtg cagattataa gttaatccag atggtttttc caatggggtt aaaacaactt
     3661 cctttgattt caaatggatt tattaaatat gatatgggag gggtttcagc taataaaaga
     3721 tttttgcgag ataaagagtt attacaaatc atgttggaga ctaataagaa aacattaata
     3781 aagtttattc cattaatggt tatcaaaatg gttttcccga aaaaaataag aagaatatta
     3841 agacgggtta attattattt ttcgttaatt ttaactaata aaaaaaacgt ttaaaatgat
     3901 taaagaaaaa atcaaaatat tatttaaata ttgcacgtta agaaaatata acactacaac
     3961 tgactatggt agacagcaag aaagatatag gattatttca ttatctatca tatcgaattt
     4021 tattagtaaa ctattagcgc tactttcgct tattttaact gttagtctga ctttaccata
     4081 tttggggcaa gatcgttttg gaatatggat gacaatcgca agctttagtg cagctttaac
     4141 ttttttagac ttaggtattg gaaatgcatt aacaaacagg attgcacatt catttgcgcg
     4201 tggcaaaaaa attagaatga ttagacagat tagtggaggg ttgactctcc tcgctatatt
     4261 agcattcatc attattgcta ttttcttaac cattgctaat tttgtcaact ggggaagctt
     4321 gcttaaagga attaacgata acacacatga tgaagtacag tttgctataa aactgttcgc
     4381 cattatattt ggtattggta tattctcgaa tggtgttcaa agaatttata tgggaatgca
     4441 aaaagcatat attagttata tatctaatgc cttctttatt ttaatatcta taatatctct
     4501 ttttatttca tctaggcttc atgcaggaat accgatgcta atcctttcga caattggtgt
     4561 tcaatatctt tcaggcctaa gcttaactat acttctaatt tataaaaaac ttataactct
     4621 taataaaata agaataaatg taaaaaagga aacgccctat ttaatctcta atggtttctt
     4681 ctttttcatt ttgcagatgg ggacattagc aacttggagt ggggataact ttataatatc
     4741 tacaacatta ggggtgacat atgtatcaat attgagtata actcagaggc tttttcaaat
     4801 ttctacagta cctttaacta tctacaatgc accgttatgg gcagcctatg ctgatgcgca
     4861 tgctcgccat gatgttgatt ttataagaaa aactctttta ggctcactta aaattgttgg
     4921 gatctcttct actactttgg cattaatatt agtaatattt ggtcaatcca tcatagcaat
     4981 atggactggg gaagaattaa gagttccgca atcgcttatt gttgcttacg cagtctggtc
     5041 tattattgat gcttattcaa atacattatc aagtttttta aatggcttaa atattattaa
     5101 acaacaagtt tttgcagtag ttactttgat attgatttca attccatcaa aatactttat
     5161 cgttagtcac tttggattaa cggctatgct aagttgtttt attattttgt atgtaactaa
     5221 ttatctaata tggtataaat gttcttttaa aaagagtatt catttacagt taaatataag
     5281 agggtgaaaa tggaatatat tccagtatat caaccagcat tatctggtaa agaaaaagaa
     5341 tatgttaatg attgtattga ttcgacttgg atttcgtcaa aagggagtta tatccagcgc
     5401 tttgaaaaaa aattcgccga gcaaaataat atccagtatg ctactactgt cagcaatggg
     5461 acagtggcat tgcatttggc tttattagcg ttaggtattt ctgaggggga tgaagttatt
     5521 gttcctacac tgacatatat agcctctgta aatgcaatta aatataccgg ggcgacaccg
     5581 gttttcgttg attcagatct tcaaacttgg caaatatcag tcgatgatat taaaaataaa
     5641 ataacaagta gaacaaaggc tataatgtgt gttcacttgt atgggcatcc ttgtgatatg
     5701 agtccaattt tagaaattgc gaaggttaat aatttattta ttattgaaga ttgtgctgag
     5761 gcttttggat caaaatataa agataaattt gtaggtacat ttggtgatat ttcaaccttt
     5821 agcttttttg gtaataaaac gataactaca ggtgaaggag gaatggttgt aactaacgat
     5881 aaaacattgt acgatagatg tttgcatttt aaagggcaag ggttagctgc acacaggcaa
     5941 tactggcatg atgtgatcgg ctataattac agaatgacaa atatttgcgc tgctattggg
     6001 ttagctcagt tagagcaagc acaattattt attgctagaa aacgtgagat cgcagaaatt
     6061 tataaaaata atctaacccc tctcattgaa gtccatcagg aaggaaatga tatatttcat
     6121 acttactgga tggtttctat ccttgccaga aatgcagagg aaagagaggt attgagatct
     6181 tttctttcgg aaaaattgac agagacacgt ccattatttt atcctgttca tacaatgcct
     6241 atgtattcag ataagtatca aaagcatcct gttgccgaaa atttaggctg gagaggtatt
     6301 aacttaccta gttttcccac cttatctaac gagcaggtta tatacatatg taacgccata
     6361 aatgaatttt ataaggataa ataaaatctc acctgtaaag gatttcttat gaagattaca
     6421 ttaaatactg atggatttaa tgaatggggg gggggggtag attttattaa ataccttttg
     6481 cgaactttag aaatcgagca ggatatattt cttgatgttc ttttgccgag ggaagatata
     6541 agttccttgc taaagaggaa tatcttccca gtaaagaata tgatcaaggc tattttaagc
     6601 ggccaaactc ctcgatggaa aaagctagaa gggtttaatg aacagtacta caagcatgct
     6661 tttgctgaaa ttactgagca gtctaagtta agtttcatta ctggcaaaag ttctgcttac
     6721 ttttcacatt acataaaatc cgactatgat attattcttc cctgtatgcg tactcctgca
     6781 gtaaatatga aaaaccgcgc atggctagga tatatttatg attttcaaca ttgttattac
     6841 ccttcttttt ttagcgaaag ggagatagct aaaagaaatt tgttttttaa aagaatgctt
     6901 gataatgcta ataatgtcat tgtcaattcc catgctgtca tttcagatgc aaaaaagttt
     6961 gttggtgatt tttctgcaaa tttacatgca ttacctttta gcccgtgtcc tgagctaaat
     7021 tggcttaatg ataactcaga tcttattgat aaatatgcta ttgataaaga ttactttata
     7081 atatgtaatc agttctggaa gcataaagat cattcaacgg cttttaaagc ttttaagaaa
     7141 tatatagaaa taaaccctga tgtatattta gtatgcacag gtgcgacgca agattataga
     7201 tttcctggat attttgacga acttatgtgt ttgcttaaaa aattgggtat atctgagaaa
     7261 gtaaaaatat tagggcatat tccaaaatta gagcaaatag aactaataaa gaatagtatt
     7321 gctgtgatac aacccacttt gtttgagggg gggccgggag gaggaattac atttgatgca
     7381 gttgcattag ggaaaaagat agtattatct gatatagagg ttaataaaga tgttgattgt
     7441 gggcatgttt attttttcca ttctcaaaat gaatactctt taactgaagc tttagttaaa
     7501 gccactgcag ttgatcatta ttatgaccca catgtcttac ttgaatctgg gataaaaagg
     7561 cgcaaaaaat gtgctgactt tattttaaat gtaataagta aagaaataga atcacgtatt
     7621 tgatataaac atataagagg tattaaatgt caaaagttgc tctcattact ggcgtaaccg
     7681 gacaggatgg gtcttacctg gcagaatttc tgctggaaaa agggtatgag gtgcatggta
     7741 tcaagcgccg cgcgtcatcg tttaatactg agcgcgtgga ccatatttat caggacccgc
     7801 acagctgcaa cccgaaattt catctgcatt atggcgacct gaccgacgcc tccaacctga
     7861 cccgcatttt acaggaagta cagccggacg aggtctacaa cctgggcgca atgagccacg
     7921 tggcggtgtc gtttgagtcg ccggaatata ccgccgatgt ggatgcgatg ggcacgctgc
     7981 gcctgctgga ggcgattcgc ttcctcggtc ttgaaaagaa aacgcggttc taccaggcct
     8041 ccacctctga actgtacggg ctggtgcagg aaattccgca gaaagagacc acgccgttct
     8101 acccgcgttc cccctatgcg gtggcgaaac tgtacgccta ctggatcacc gtcaactacc
     8161 gtgaatccta cggtatttac gcctgtaacg gcattctgtt taaccatgag tccccgcgtc
     8221 gcggcgaaac cttcgtcacc cgtaagatca cccgcgccat cgccaatatc gcgcagggac
     8281 tggagtcctg cctgtatctc ggcaacatgg actcgctgcg cgactggggc catgcgaaag
     8341 attacgtgcg gatgcagtgg atgatgttac agcaggagca gccggaagat ttcgtgattg
     8401 ccaccggcgt gcagtattcc gtacgccagt ttgtggagct ggcggcggcg caactgggga
     8461 taaaactgcg ctttgaaggc gaaggcatta atgagaaagg gattgtggta tccgttaccg
     8521 gacacgatgc gccgggcgtg aaaccgggcg atgtgattgt cgccgttgat ccgcgttatt
     8581 tccgtccggc ggaagtggaa accctgctgg gcgacccgtc caaagcgcat gagaaactgg
     8641 gctggaaacc ggaaatcacc ctgtcggaga tggtctccga gatggtggcg aacgatctgg
     8701 aggccgcgaa aaaacactca ctgctgaaat ctcatggatt caatgtaaat ttatctttgg
     8761 aatgaccatg aacaagcaac gaatttttgt ggcgggccat cgcgggatgg tgggctccgc
     8821 cattgtacgg cagcttgcgc agcgcggcga cgtggaactg gtgctgcgca cccgcgatga
     8881 gctggatctg ctcgacgggc gcgcggtaca ggcgttcttt gccgggacgg gtatcgacca
     8941 ggtttatctg gcggcggcga aagtgggcgg cattgtcgcc aacaacacgt atccggcgga
     9001 ttttatttat gaaaacatga tgatagagag caacattatt cacgccgcgc acctgcacaa
     9061 cgtgaacaaa ctgctgtttc tcggttcgtc ctgtatctat ccgaaactgg caaggcagcc
     9121 gatggcggaa agcgagctgc tgcagggaac gctggagccg accaacgagc cgtatgccat
     9181 cgccaagatc gccgggatta aactgtgcga gtcctacaac cggcagtacg gtcgcgacta
     9241 ccgttcggtg atgccgacca acctgtacgg cccgcatgat aatttccatc cggacaattc
     9301 acatgtgatc ccggcgctgc tgcgccgctt tcatgaggcc gcgcagagcc acgcgccgga
     9361 ggtggtggtg tggggcagcg gcacgccgat gcgcgaattt ctgcacgttg acgatatggc
     9421 ggcggccagt attcacgtga tggagctgtc gcgcgaagtg tggcaggaga acaccgctcc
     9481 gatgctgtcg cacattaacg tcggcactgg cgtggactgc accatcagcg agctggcgca
     9541 gaccatcgca aaggtggtgg gttaccaggg ccgggtggtg ttcgatgccg cgaagccgga
     9601 cggcacgccg cgtaaattgc tcgacgtcac gcgcctgcat cagcttggct ggtatcacga
     9661 aatttcactg gaggcagggc ttgccggtac ttaccagtgg ttccttgaga atcagcaacg
     9721 gttccggggg tgacaatgtt tttacgtcag gaagatttcg ccgccgtggt gcgggccacg
     9781 cccctcatct ccctagattt cattgtggaa aacggccagg gggaaatttt actgggccag
     9841 cgtctcaacc gtccggcgca gggctactgg tttgtgccgg ggggacgggt gcgcaaagac
     9901 gaaacgctgg aggccgcctt tgcacgcctg acgcaggcgg aactgggcgt gcgtctgccg
     9961 ctggcggcag ggacgtttta tggcgtctgg cagcacttct atgacgacaa cttttccggt
    10021 gaggattttt caactcacta catcgtgctc ggctttcgtc tgcgcgtggc ggagagcgat
    10081 ttactcctgc ctgacgcgca gcatggcagt taccgctggc tgacgccgga acagctgctg
    10141 gcaagcgaca atgttcatga taacagccgg gcttattttc aaaatgcacc ctattctgtc
    10201 attggattag acaaaaagga cgtcaagtat gtctgatgta tcattaatag ccgttgtaat
    10261 ggctggtggt acggggagtc gcctttggcc tctatcccgg gaactctacc caaaacaatt
    10321 tttacagctt tctggagagc attccttatt acagacaacc ttgcttcggc tgtcggcact
    10381 tgcctgtaaa gatccattag ttatcacaaa cgagcagcac cgttttattg ttgccgaaca
    10441 gctacggcaa attgatcagc tacacgataa cattatcctt gaaccgtgtg ggaggaatac
    10501 tgctccagca attgcgcttg ctgcgttttc agctcttaaa cgtaatgaac aggaggatcc
    10561 tttacttcta gttcttgcag ccgatcatgt tatcgctaaa gaaaatgttt tttgcaacgc
    10621 tattaagaaa gcagtgccaa ttgctgaaaa tggtaatatt gttacatttg gtatcatacc
    10681 tgagtatgca gaaactggtt atggttatat agagcgtggt gcgccgttct cggtaaatgg
    10741 aaattcaaca ggaatagatt tttatcatgt aaaaaacttt gttgaaaagc cggagcgatt
    10801 gacagcagaa aaatatatct ctgcagggaa ctatttctgg aatagtggca tgtttatgtt
    10861 taaggccagt gtttatctga atgaattaaa aaaattcaga ccggatattt atagtatttg
    10921 tgaacaggtg gtttcttcct catatcgtga ccttgatttt attcgtattc ctgaagcttt
    10981 gtttaaagat tgtcctgcag agtctgttga ttttgctgtt atggaaaaaa cggaacattg
    11041 cattgtttgt ccgattaata tcggttggag tgatgtcggt tcctggcagt ctctctggga
    11101 tatcagcgaa aaaactaatg agggagatgt ttgtaaaggt gatatcttga catataatac
    11161 taagaataat tatatatatt cagagtctgc attggttgct gctgtaggcg ttgaggatat
    11221 cgttattgta caaacaaagg atgccatact cgtttctaaa aaatctgacg tccaggatgt
    11281 aaaaaaaatc gttgaaatgc taaagactca agatcgtaca gaatatattt ctcatcgtga
    11341 agtttttcgg ccatggggta aatttgactc aatagatcaa ggcgagcgat acagagttaa
    11401 gaagattgtt gtaaaaccag gagaagggct ttctttacgt atgcatcatc atcgttcaga
    11461 acactggatt gtgctttctg gtacggctaa agttaccctg gatgataaaa cgatgctagt
    11521 aactgccaat gaatcaattt atattccatt gggtgcaacg tacagtctgg aaaatccagg
    11581 tgttattcct cttaatctta tagaagtcag ttcaggcgat tatttgggag aagatgatat
    11641 tgttcggcag aaagaacgtt acagaaaaga tgattgaatc atgaataaat taacctgttt
    11701 caaggcctac gacattcgcg gcaggctggg cgaagagctc aatgaagata tcgcgtggcg
    11761 gattggccgc gcctacggcg aatatttaaa accgaaaacc atcgtgctgg gcggcgacgt
    11821 gcgtctgacc agcgaggcgc tgaagctggc gctggcgaaa gggttacagg acgcgggcgt
    11881 cgacgtgctg gatatcggta tgtccggcac cgaagagatt tacttcgcca ccttccacct
    11941 cggcgtggac ggcggtattg aagtgaccgc cagccataac ccgatggact acaacggcat
    12001 gaagctggta cgcgagggcg cccgcccgat aagcggcgac accggtctgc gcgacgttca
    12061 gcgtctggca gaagcgggca atttcccgcc ggtgaacgag gccgcgcgcg gcagctacag
    12121 acaaatcagc ctgcgcgacg cctacatcgg ccacctgctg gggtatatca gcgtcagcaa
    12181 tctcaccccg ctgaagctgg tggtgaattc cggcaacggc gcggcggggc cggtcattga
    12241 cgccatcgaa gcgcgtctga aggcgctggg cgcgccggtg gagttcatca aaatccacaa
    12301 caccccggac ggcaccttcc cgaacggcat tcccaacccg ttgctgccgg agtgtcgcga
    12361 cgacacccgc aaggccgtta ttgaacacgg ggcggacatg ggcatcgcct ttgacggcga
    12421 cttcgaccgc tgcttcctgt tcgatgagaa agggcagttt atcgaggggt actacatcgt
    12481 cgggctgctg gcggaagcgt ttctggaaaa acacccgggg gcgaagatta tccacgaccc
    12541 gcgcctgacc tggaacacgg aggcagtggt gacggcggcg ggcgggacgc cggtgatgtc
    12601 aaaaaccggg cacgccttta tcaaggagcg gatgcgtacg gaggatgcca tttatggcgg
    12661 ggaaatgagc gcgcatcact attttcgtga ttttgcctac tgcgacagcg ggatgatccc
    12721 gtggctgctg gtggcggagc tggtgtgcct gaaggggcag tcgctgggtg aactggtccg
    12781 cgaccggatg gcggcgttcc cggcgagcgg ggaaatcaac agcaggctgg cggagccggc
    12841 ggcggccatc gcgcgggtgg aagcgcactt tgcggaagag gcgcaggcag tggaccgcac
    12901 ggacggtctc agcatgtcgt tcgccaactg gcgtttcaac ctgcgctcgt cgaacaccga
    12961 accggtggtg cgcctgaatg tggaatccaa agcaaataca gaattgatgg aagaaaaaac
    13021 gcaagcaatc ctgacattat tacgaaaata gctttttagt gtgacataca tatagagtta
    13081 ttccatagtt aattcattta tacaatcaat gcgatacgaa tccgtaaaag ctatccatat
    13141 tttccaattc tgagttaaca tctaaagcac atttcaagcc gcgctctcgt cgcgcggtga
    13201 ccacacctga caggagtatg taatgtccaa gcaacagatc ggcgtcgtcg gtatggcagt
    13261 gatggggcgc aacctcgcgc tcaacatcga aagccgtggt tataccgtct ccgttttcaa
    13321 ccgctcccgt gaaaagaccg aagaagtgat tgccgagaat cccggcaaaa agctggtgcc
    13381 ttattacacg gtgaaagagt ttgttgaatc cctcgaaacg cctcgtcgta tcctgttaat
    13441 ggtgaaagcg ggcgcaggta ctgatgcagc tatcgattcg ttgaaaccgt atctggaaaa
    13501 aggcgatatc attattgatg gcggcaacac cttcttccag gacacaatcc gacgcaatcg
    13561 cgagctgtct gcggaaggtt ttaactttat cggtaccggt gtttccggtg gtgaagaggg
    13621 cgcgctgaaa gggccatcta tcatgcctgg cggtcagaaa gatgcctatg aactggtggc
    13681 gccgatcctg acgaagattg ctgccgtggc ggaagatggc gaaccgtgcg tgacctatat
    13741 cggcgccgat ggtgctggtc actacgtcaa gatggtccac aatggtattg aatatggcga
    13801 tatgcagctt atcgctgaag cttactccct gctgaaaggc ggcctgaatc tcagcaatga
    13861 agagttggcg aacactttta ctgagtggaa taacggcgag ctgagcagtt atctgatcga
    13921 catcactaaa gacatcttca ctaaaaaaga tgaagacgga aactacttgg tggatgtcat
    13981 tcttgatgaa gccgccaaca aagggaccgg taaatggacc agccagagcg cgctggatct
    14041 gggcgaaccg ttgtcgctga ttaccgaatc tgtctttgcg cgttacatct cttcgttgaa
    14101 agcgcaacgt gttgccgcat ctaaagtgct ctccgggccg aaagcgcaac cggcaggcga
    14161 caaagcggaa tttatcgaga aagtgcgtcg cgcgctgtat cttggcaaga tcgtctccta
    14221 tgcgcagggc ttctcgcagc tacgcgccgc gtctgatgaa tatcactggg atctcaacta
    14281 cggcgagatt gctaagattt tccgtgcggg ttgtatcatt cgc
//
