LOCUS       X56793                 22080 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  S.enterica (group B) rfb gene cluster.
ACCESSION   X56793 M29713
VERSION     X56793.1
KEYWORDS    abe gene; CDP-abequose synthase; CDP-glucose 4.6-dehydratase; ddhA
            gene; ddhB gene; ddhC gene; ddhD gene; dTDP-6-deoxy-L-mannose
            dehydrogenase; dTDP-dehydrorhamnose reductase; dTDP-glucose
            oxidoreductase; dTDP-glucose-4.6-dehydratase; galF gene;
            glucose-1-P cytidyltransferase; glucose-1-P thymidydyltransferase;
            manB gene; manC gene; Manose-1-Pguanylyltransferase;
            oxidoreductase; Phosphomanomutase; rfb gene cluster; rmlA gene;
            rmlB gene; rmlC gene; rmlD gene; undecaprenyl-P galactose-P
            transferase; wbaN gene; wbaP gene; wbaU gene; wbaV gene; wcaL gene;
            wzx gene.
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 22080)
  AUTHORS   Wyk,P. and Reeves,P.
  TITLE     Identification and sequence of the gene for abequose synthase,
            which confers antigenic specificity on group B salmonellae:
            homology with galactose epimerase
  JOURNAL   J. Bacteriol. 171 (10), 5687-5693 (1989)
   PUBMED   2793832
REFERENCE   2  (bases 1 to 22080)
  AUTHORS   Jiang,X.M., Neal,B., Santiago,F., Lee,S.J., Romana,L.K. and
            Reeves,P.R.
  TITLE     Structure and sequence of the rfb (O antigen) gene cluster of
            Salmonella serovar typhimurium (strain LT2)
  JOURNAL   Mol. Microbiol. 5 (3), 695-713 (1991)
   PUBMED   1710759
REFERENCE   3  (bases 1 to 22080)
  AUTHORS   Reeves,P.
  TITLE     Evolution of Salmonella O antigen variation by interspecific gene
            transfer on a large scale
  JOURNAL   Trends Genet. 9 (1), 17-22 (1993)
   PUBMED   8434412
REFERENCE   4  (bases 1 to 22080)
  AUTHORS   Liu,D., Haase,A.M., Lindqvist,L., Lindberg,A.A. and Reeves,P.R.
  TITLE     Glycosyl transferases of O-antigen biosynthesis in Salmonella
            enterica: identification and characterization of transferase genes
            of groups B, C2, and E1
  JOURNAL   J. Bacteriol. 175 (11), 3408-3413 (1993)
   PUBMED   7684736
REFERENCE   5  (bases 1 to 22080)
  AUTHORS   Stevenson,G., Andrianopoulos,K., Hobbs,M. and Reeves,P.R.
  TITLE     Organization of the Escherichia coli K-12 gene cluster responsible
            for production of the extracellular polysaccharide colanic acid
  JOURNAL   J. Bacteriol. 178 (16), 4885-4893 (1996)
   PUBMED   8759852
REFERENCE   6  (bases 1 to 22080)
  AUTHORS   Marolda,C.L. and Valvano,M.A.
  TITLE     The GalF protein of Escherichia coli is not a UDP-glucose
            pyrophosphorylase but interacts with the GalU protein possibly to
            regulate cellular levels of UDP-glucose
  JOURNAL   Mol. Microbiol. 22 (5), 827-840 (1996)
   PUBMED   8971705
REFERENCE   7  (bases 1 to 22080)
  AUTHORS   Reeves,P.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-NOV-1990) P.R. Reeves, G08 DEPT OF MICROBIOLOGY,
            UNIVERSITY OF SYDNEY, NSW 2006, AUSTRALIA
COMMENT     On Jun 13, 2005 this sequence version replaced M29713.1.
FEATURES             Location/Qualifiers
     source          1..22080
                     /organism="Salmonella enterica"
                     /mol_type="genomic DNA"
                     /strain="group B, serovar typhimurium, strain LT2"
                     /isolate="SL1654"
                     /db_xref="taxon:28901"
     gene            17..1237
                     /gene="wcaL"
     CDS             17..1237
                     /gene="wcaL"
                     /note="part of cluster for colanic acid prodaction"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAA40132.1"
                     /db_xref="GOA:P26388"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/Swiss-Prot:P26388"
                     /translation="MKVSFFLLKFPLSSETFVLNQITAFIDMGHEVEIVALQKGDTQH
                     THAAWEKYGLAAKTRWLQDEPQGRLAKLRYRACKTLPGLHRAATWKALNFTRYGDESR
                     NLILSAICAQVSQPFVADVFIAHFGPAGVTAAKLRELGVLRGKIATIFHGIDISSREV
                     LSHYTPEYQQLFRRGDLMLPISDLWAGRLKSMGCPPEKIAVSRMGVDMTRFTHRSVKA
                     PGMPLEMISVARLTEKKGLHVAIEACRQLKAQGVAFRYRILGIGPWERRLRTLIEQYQ
                     LEDVIEMPGFKPSHEVKAMLDDADVFLLPSITGTDGDMEGIPVALMEAMAVGIPVVST
                     VHSGIPELVEAGKSGWLVPENDAQALAARLAEFSRIDHDTLESVITRAREKVAQDFNQ
                     QAINRQLASLLQTI"
     gene            1248..2651
                     /gene="ORF 1.3"
     CDS             1248..2651
                     /gene="ORF 1.3"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAA40113.1"
                     /db_xref="GOA:P26389"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="InterPro:IPR011050"
                     /db_xref="InterPro:IPR012334"
                     /db_xref="UniProtKB/Swiss-Prot:P26389"
                     /translation="MPATKFSRRTLLTAGSALAVLPFLRALPVQAREPRETVDIKDYP
                     ADDGIASFKQAFADGQTVVVPPGWVCENINAAITIPAGKTLRVQGAVRGNGRGRFILQ
                     DGCQVVGEQGGSLHNVTLDVRGSDCVIKGVAMSGFGPVAQIFIGGKEPQVMRNLIIDD
                     ITVTHANYAILRQGFHNQMDGARITHSRFSDLQGDAIEWNVAIHDRDILISDHVIERI
                     NCTNGKINWGIGIGLAGSTYDNSYPEDQAVKNFVVANITGSDCRQLVHVENGKHFVIR
                     NVKAKNITPGFSKNAGIDNATIAIYGCDNFVIDNIDMTNSAGMLIGYGVVKGKYLSIP
                     QNFKLNAIRLDNRQVAYKLRGIQISSGNTPSFVAITNVRMTRATLELHNQPQHLFLRN
                     INVMQTSAIGPALKMHFDLRKDVRGQFMARQDTLLSLANVHAINENGQSSVDIDRINH
                     QTVNVEAVNFSLPKRGG"
     gene            2829..3722
                     /gene="galF"
     CDS             2829..3722
                     /gene="galF"
                     /function="possibly in regulation of cellular levels of
                     UDP-glucose"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glucose-1-phosphate
                     uridylyltransferase"
                     /protein_id="CAA40114.1"
                     /db_xref="GOA:P0A2K7"
                     /db_xref="InterPro:IPR005774"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="UniProtKB/Swiss-Prot:P0A2K7"
                     /translation="MMNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEIVLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNV
                     RQAQPLGLGHSILCARPVVGDNPFIVVLPDIIIDDATADPLRYNLAAMVARFNETGRS
                     QVLAKRMKGDLSEYSVIQTKEPLDNEGKVSRIVEFIEKPDQPQTLDSDLMAVGRYVLS
                     ADIWAELERTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFRKSIEQLLHE"
     gene            4099..5184
                     /gene="rmlB"
     CDS             4099..5184
                     /gene="rmlB"
                     /EC_number="4.2.1.46"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="CDS starts with gtg"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="CAA40115.1"
                     /db_xref="GOA:P26391"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="PDB:1G1A"
                     /db_xref="PDB:1KEU"
                     /db_xref="PDB:1KEW"
                     /db_xref="UniProtKB/Swiss-Prot:P26391"
                     /translation="MKILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLS
                     DISESNRYNFEHADICDSAEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYALLEVARKYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTA
                     YAPSSPYSASKASSDHLVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KPLPIYGKGDQIRDWLYVEDHARALHMVVTEGKAGETYNIGGHNEKKNLDVVFTICDL
                     LDEIVPKATSYREQITYVADRPGHDRRYAIDAGKISRELGWKPLETFESGIRKTVEWY
                     LANTQWVNNVKSGAYQSWIEQNYEGRQ"
     gene            5184..6083
                     /gene="rmlD"
     CDS             5184..6083
                     /gene="rmlD"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="incorrectly designated rfbA in reference [2];
                     dTDP-glucose oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-L-mannose dehydrogenase"
                     /protein_id="CAA40116.1"
                     /db_xref="GOA:P26392"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="PDB:1KBZ"
                     /db_xref="PDB:1KC1"
                     /db_xref="PDB:1KC3"
                     /db_xref="PDB:1N2S"
                     /db_xref="UniProtKB/Swiss-Prot:P26392"
                     /translation="MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEFCGDFSNPK
                     GVAETVRKLRPDVIVNAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHY
                     STDYVFPGTGDIPWQETDATSPLNVYGKTKLAGEKALQDNCPKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKERQTLSVINDQYGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAG
                     GTTTWHDYAALVFDEARKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFD
                     LILPQWELGVKRMLTEMFTTTTI"
     gene            6131..7009
                     /gene="rmlA"
     CDS             6131..7009
                     /gene="rmlA"
                     /note="referred to as orf6.1 in reference [2]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="CAA40117.1"
                     /db_xref="GOA:P26393"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="PDB:1IIM"
                     /db_xref="PDB:1IIN"
                     /db_xref="PDB:1MP3"
                     /db_xref="PDB:1MP4"
                     /db_xref="PDB:1MP5"
                     /db_xref="UniProtKB/Swiss-Prot:P26393"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGH
                     DDCALVLGDNIFYGHDLPKLMEAAVNKESGATVFAYHVNDPERYGVVEFDQKGTAVSL
                     EEKPLQPKSNYAVTGLYFYDNSVVEMAKNLKPSARGELEITDINRIYMEQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAFRKNFINAQQVIELAGPL
                     SKNDYGKYLLKMVKGL"
     gene            7010..7561
                     /gene="rmlC"
     CDS             7010..7561
                     /gene="rmlC"
                     /note="dTDP-6-deoxy-D-glucose-3,5 epimerase"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAA40118.1"
                     /db_xref="GOA:P26394"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="PDB:1DZR"
                     /db_xref="PDB:1DZT"
                     /db_xref="UniProtKB/Swiss-Prot:P26394"
                     /translation="MMIVIKTAIPDVLILEPKVFGDERGFFFESYNQQTFEELIGRKV
                     TFVQDNHSKSKKNVLRGLHFQRGENAQGKLVRCAVGEVFDVAVDIRKESPTFGQWVGV
                     NLSAENKRQLWIPEGFAHGFVTLSEYAEFLYKATNYYSPSSEGSILWNDEAIGIEWPF
                     SQLPELSAKDAAAPLLDQALLTE"
     gene            7567..8559
                     /gene="ddhD"
     CDS             7567..8559
                     /gene="ddhD"
                     /note="cds starts with gtg; orf7.6 is possibly rfbI, which
                     encodes CDP-6-deoxy-delta-(3,4)-glucoseen reductase"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAA40119.1"
                     /db_xref="GOA:P26395"
                     /db_xref="InterPro:IPR001041"
                     /db_xref="InterPro:IPR001221"
                     /db_xref="InterPro:IPR001433"
                     /db_xref="InterPro:IPR001709"
                     /db_xref="InterPro:IPR006058"
                     /db_xref="InterPro:IPR008333"
                     /db_xref="InterPro:IPR012675"
                     /db_xref="InterPro:IPR017927"
                     /db_xref="InterPro:IPR017938"
                     /db_xref="UniProtKB/Swiss-Prot:P26395"
                     /translation="MSHIIKIFPSNIEFSGREDESILDAALSAGIHLEHSCKAGDCGI
                     CESDLLAGEVVDSKGNIFGQGDKILTCCCKPKTALELNAHFFPELAGQTKKIVPCKVN
                     SAVLVSGDVMTLKLRTPPTAKIGFLPGQYINLHYKGVTRSYSIANSDESNGIELHVRN
                     VPNGQMSSLIFGELQENTLMRIEGPCGTFFIRESDRPIIFLAGGTGFAPVKSMVEHLI
                     QGKCRREIYIYWGMQYSKDFYSALPQQWSEQHDNVHYIPVVSGDDAEWGGRKGFVHHA
                     VMDDFDSLEFFDIYACGSPVMIDASKKDFMMKNLSVEHFYSDAFTASNNIEDNL"
     gene            8556..9329
                     /gene="ddhA"
     CDS             8556..9329
                     /gene="ddhA"
                     /EC_number="2.7.7.33"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate cytidylyltransferase"
                     /protein_id="CAA40120.1"
                     /db_xref="GOA:P26396"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR013446"
                     /db_xref="UniProtKB/Swiss-Prot:P26396"
                     /translation="MKAVILAGGLGTRLSEETIVKPKPMVEIGGKPILWHIMKMYSVH
                     GIKDFIICCGYKGYVIKEYFANYFLHMSDVTFHMAENRMEVHHKRVEPWNVTLVDTGD
                     SSMTGGRLKRVAEYVKDDEAFLFTYGDGVADLDIKATIDFHKAHGKKATLTATFPPGR
                     FGALDIRAGQVRSFQEKPKGDGAMINGGFFVLNPSVIDLIDNDATTWEQEPLMTLAQQ
                     GELMAFEHPGFWQPMDTLRDKVYLEGLWEKGKAPWKTWE"
     gene            9334..10413
                     /gene="ddhB"
     CDS             9334..10413
                     /gene="ddhB"
                     /EC_number="4.2.1.45"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glucose 4,6-dehydratase"
                     /protein_id="CAA40121.1"
                     /db_xref="GOA:P26397"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR013445"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="PDB:1WVG"
                     /db_xref="UniProtKB/Swiss-Prot:P26397"
                     /translation="MIDKNFWQGKRVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAP
                     TVPSLFEIVRLNDLMESHIGDIRDFEKLRNSIAEFKPEIVFHMAAQPLVRLSYEQPIE
                     TYSTNVMGTVHLLETVKQVGNIKAVVNITSDKCYDNREWVWGYRENEPMGGYDPYSNS
                     KGCAELVASAFRNSFFNPANYEQHGVGLASVRAGNVIGGGDWAKDRLIPDILRSFENN
                     QQVIIRNPYSIRPWQHVLEPLSGYIVVAQRLYTEGAKFSEGWNFGPRDEDAKTVEFIV
                     DKMVTLWGDDASWLLDGENHPHEAHYLKLDCSKANMQLGWHPRWGLTETLGRIVKWHK
                     AWIRGEDMLICSKREISDYMSATTR"
     gene            10440..11753
                     /gene="ddhC"
     CDS             10440..11753
                     /gene="ddhC"
                     /note="Referred to as orf10.4 in reference [2]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-4-keto-6-deoxy-D-glucose-3-dehydrase"
                     /protein_id="CAA40122.1"
                     /db_xref="GOA:P26398"
                     /db_xref="InterPro:IPR000653"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="UniProtKB/Swiss-Prot:P26398"
                     /translation="MTANNLREQISQLVAQYANEALSPKPFVAGTSVVPPSGKVIGAK
                     ELQLMVEASLDGWLTTGRFNDAFEKKLGEFIGVPHVLTTTSGSSANLLALTALTSPKL
                     GERALKPGDEVITVAAGFPTTVNPAIQNGLIPVFVDVDIPTYNIDASLIEAAVTEKSK
                     AIMIAHTLGNAFNLSEVRRIADKYNLWLIEDCCDALGTTYEGQMVGTFGDIGTVSFYP
                     AHHITMGEGGAVFTKSGELKKIIESFRDWGRDCYCAPGCDNTCGKRFGQQLGSLPQGY
                     DHKYTYSHLGYNLKITDMQAACGLAQLERVEEFVEQRKANFSYLKQGLQSCTEFLELP
                     EATEKSDPSWFGFPITLKETSGVNRVELVKFLDEAKIGTRLLFAGNLIRQPYFANVKY
                     RVVGELTNTDRIMNQTFWIGIYPGLTTEHLDYVVSKFEEFFGLNF"
     gene            11781..12680
                     /gene="abe"
     CDS             11781..12680
                     /gene="abe"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-abequose synthase"
                     /protein_id="CAA40123.1"
                     /db_xref="GOA:P0A1P4"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/Swiss-Prot:P0A1P4"
                     /translation="MTFLKEYVIVSGASGFIGKHLLEALKKSGISVVAITRDVIKNNS
                     NALANVRWCSWDNIELLVEELSIDSALIGIIHLATEYGHKTSSLINIEDANVIKPLKL
                     LDLAIKYRADIFLNTDSFFAKKDFNYQHMRPYIITKRHFDEIGHYYANMHDISFVNMR
                     LEHVYGPGDGENKFIPYIIDCLNKKQSCVKCTTGEQIRDFIFVDDVVNAYLTILENRK
                     EVPSYTEYQVGTGAGVSLKDFLVYLQNTMMPGSSSIFEFGAIEQRDNEIMFSVANNKN
                     LKAMGWKPNFDYKKGIEELLKRL"
     gene            12762..14054
                     /gene="wzx"
     CDS             12762..14054
                     /gene="wzx"
                     /note="hypothetical protein with 12 predicted
                     transmembrane segments which possibly functions in export
                     of O-antigen; Referred to as orf12.8 in reference [2]; cds
                     starts with gtg"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAA40124.1"
                     /product="flippase"
                     /db_xref="GOA:P26400"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/Swiss-Prot:P26400"
                     /translation="MKVQLLKIPSHLIVAGSSWLSKIIIAGVQLASISYLISMLGEEK
                     YAIFSLLTGLLVWCSAVDFGIGTGLQNYISECRAKNKSYDAYIKSALHLSFIAIIFFI
                     ALFYIFSGVISAKYLSSFHEVLQDKTRMLFFTSCLVFSSIGIGAIAYKILFAELVGWK
                     ANLLNALSYMIGMLGLLYIYYRGISVDIKLSLIVLYLPVGMISLCYIVYRYIKLYHVK
                     TTKSHYIAILRRSSGFFLFTLLSIVVLQTDYMVISQRLTPADIVQYTVTMKIFGLVFF
                     IYTAILQALWPICAELRVKQQWKKLNKMIGVNILLGSLYVVGCTIFIYLFKEQIFSVI
                     AKDINYQVSILSFMLIGIYFCIRVWCDTYAMLLQSMNYLKILWILVPLQAIIGGIAQW
                     YFSSTLGISGVLLGLIISFALTVFWGLPLTYLIKANKG"
     gene            14059..15060
                     /gene="wbaV"
     CDS             14059..15060
                     /gene="wbaV"
                     /note="orf14.1 is possibly rfbV, which encodes abequosyl
                     transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAA40125.1"
                     /db_xref="GOA:P26401"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/Swiss-Prot:P26401"
                     /translation="MLISFCIPTYNRKQYLEELLNSINNQEKFNLDIEICISDNASTD
                     GTEEMIDVWRNNYNFPIIYRRNSVNLGPDRNFLASVSLANGDYCWIFGSDDALAKDSL
                     AILQTYLDSQADIYLCDRKETGCDLVEIRNPHRSWLRTDDELYVFNNNLDREIYLSRC
                     LSIGGVFSYLSSLIVKKERWDAIDFDASYIGTSYPHVFIMMSVFNTPGCLLHYISKPL
                     VICRGDNDSFEKKGKARRILIDFIAYLKLANDFYSKNISLKRAFENVLLKERPWLYTT
                     LAMACYGNSDEKRDLSEFYAKLGCNKNMINTVLRFGKLAYAVKNITVLKNFTKRIIK"
     gene            15379..16440
                     /gene="wbaU"
     CDS             15379..16440
                     /gene="wbaU"
                     /note="Referred to as orf15.4 in reference [2]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAA40126.1"
                     /db_xref="GOA:P26402"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/Swiss-Prot:P26402"
                     /translation="MIVNLSRLGKSGTGMWQYSIKFLTALREIADVDAIICSKVHADY
                     FEKLGYAVVTVPNIVSNTSKTSRLRPLVWYVYSYWLALRVLIKFGNKKLVCTTHHTIP
                     LLRNQTITVHDIRPFYYPDSFIQKVYFRFLLKMSVKRCKHVLTVSYTVKDSIAKTYNV
                     DSEKISVIYNSVNKSDFIQKKEKENYFLAVGASWPHKNIHSFIKNKKVWSDSYNLIIV
                     CGRTDYAMSLQQMVVDLELKDKVTFLHEVSFNELKILYSKAYALVYPSIDEGFGIPPI
                     EAMASNTPVIVSDIPVFHEVLTNGALYVNPDDEKSWQSAIKNIEQLPDAISRFNNYVA
                     RYDFDNMKQMVGNWLAESK"
     gene            16441..17385
                     /gene="wbaN"
     CDS             16441..17385
                     /gene="wbaN"
                     /note="Referred to as orf16.5 in reference [2]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAA40127.1"
                     /db_xref="GOA:P26403"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/Swiss-Prot:P26403"
                     /translation="MKITLIIPTYNAGSLWPNVLDAIKQQTIYPDKLIVIDSGSKDET
                     VPLASDLKNISIFNIDSKDFNHGGTRNLAVAKTLDADVIIFLTQDAILADSDAIKNLV
                     YYFSDPLIAAVCGRQLPHKDANPLAVHARNFNYSSKSIVKSKADIEKLGIKTVFMSNS
                     FAAYRRSVFEELSGFPEHTILAEDMFMAAKMIQAGYKVAYCAEAVVRHSHNYTPREEF
                     QRYFDTGVFHACSPWIQRDFGGAGGEGFRFVKSEIQFLLKNAPFWIPRALLTTFAKFL
                     GYKLGKHWQSLPLSTCRYFSMYKSYWNNIQYSSSKEIK"
     gene            17386..18825
                     /gene="manC"
     CDS             17386..18825
                     /gene="manC"
                     /EC_number="2.7.7.22"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase (GDP)"
                     /protein_id="CAA40128.1"
                     /db_xref="GOA:P26404"
                     /db_xref="InterPro:IPR001538"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR006375"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/Swiss-Prot:P26404"
                     /translation="MSFLPVIMAGGTGSRLWPLSREYHPKQFLSVEGKLSMLQNTIKR
                     LASLSTEEPVVICNDRHRFLVAEQLREIDKLANNIILEPVGRNTAPAIALAAFCALQN
                     ADNADPLLLVLAADHVIQDEIAFTKAVRHAEEYAANGKLVTFGIVPTHAETGYGYIRR
                     GELIGNDAYAVAEFVEKPDIDTAGDYFKSGKYYWNSGMFLFRASSYLNELKYLSPEIY
                     KACEKAVGHINPDLDFIRIDKEEFMSCPSDSIDYAVMEHTQHAVVIPMSAGWSDVGSW
                     SSLWDISNKDHQRNVLKGDIFAHACNDNYIYSEDMFISAIGVSNLVIVQTTDALLVAN
                     KDTVQDVKKIVDYLKRNDRNEYKQHQEVFRPWGKYNVIDSGKNYLVRCITVKPGEKFV
                     AQMHHHRAEHWIVLSGTARVTKGEQTYMVSENESTFIPPNTIHALENPGMTPLKLIEI
                     QSGTYLGEDDIIRLEQRSGFSKEWTNERS"
     gene            18812..20245
                     /gene="manB"
     CDS             18812..20245
                     /gene="manB"
                     /EC_number="5.4.2.8"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="CAA40129.1"
                     /db_xref="GOA:P26405"
                     /db_xref="InterPro:IPR005843"
                     /db_xref="InterPro:IPR005844"
                     /db_xref="InterPro:IPR005845"
                     /db_xref="InterPro:IPR005846"
                     /db_xref="InterPro:IPR016055"
                     /db_xref="InterPro:IPR016066"
                     /db_xref="UniProtKB/Swiss-Prot:P26405"
                     /translation="MNVVNNSRDVIYSSGIVFGTSGARGLVKDFTPQVCAAFTVSFVA
                     VMQEHFSFDTVALAIDNRPSSYGMAQACAAALADKGVNCIFYGVVPTPALAFQSMSDN
                     MPAIMVTGSHIPFERNGLKFYRPDGEITKHDEAAILSVEDTCSHLELKELIVSEMAAV
                     NYISRYTSLFSTPFLKNKRIGIYEHSSAGRDLYKPLFIALGAEVVSLGRSDNFVPIDT
                     EAVSKEDREKARSWAKEFDLDAIFSTDGDGDRPLIADEAGEWLRGDILGLLCSLALDA
                     EAVAIPVSCNSIISSGRFFKHVKLTKIGSPYVIEAFNELSRSYSRIVGFEANGGFLLG
                     SDICINEQNLHALPTRDAVLPAIMLLYKSRNTSISALVNELPTRYTHSDRLQGITTDK
                     SQSLISMGRENLSNLLSYIGLENEGAISTDMTDGMRITLRDGCIVHLRASGNAPELRC
                     YAEANLLNRAQDLVNTTLANIKKRCLL"
     gene            20317..21747
                     /gene="wbaP"
     CDS             20317..21747
                     /gene="wbaP"
                     /EC_number="2.7.8.6"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAA40130.1"
                     /db_xref="GOA:P26406"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017472"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/Swiss-Prot:P26406"
                     /translation="MDNIDNKYNPQLCKIFLAISDLIFFNLALWFSLGCVYFIFDQVQ
                     RFIPQDQLDTRVITHFILSVVCVGWFWIRLRHYTIRKPFWYELKEIFRTIVIFAIFDL
                     ALIAFTKWQFSRYVWVFCWTFALILVPFFRALTKHLLNKLGIWKKKTIILGSGQNARG
                     AYSALQSEEMMGFDVIAFFDTDASDAEINMLPVIKDTEIIWDLNRTGDVHYILAYEYT
                     ELEKTHFWLRELSKHHCRSVTVVPSFRGLPLYNTDMSFIFSHEVMLLRIQNNLAKRSS
                     RFLKRTFDIVCSIMILIIASPLMIYLWYKVTRDGGPAIYGHQRVGRHGKLFPCYKFRS
                     MVMNSQEVLKELLANDPIARAEWEKDFKLKNDPRITAVGRFIRKTSLDELPQLFNVLK
                     GDMSLVGPRPIVSDELERYCDDVDYYLMAKPGMTGLWQVSGRNDVDYDTRVYFDSWYV
                     KNWTLWNDIAILFKTAKVVLRRDGAY"
     gene            21911..>22080
                     /gene="gnd"
     CDS             21911..>22080
                     /gene="gnd"
                     /note="overlaps with X15651(1..170)"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="CAA40131.1"
                     /db_xref="GOA:P14062"
                     /db_xref="InterPro:IPR006113"
                     /db_xref="InterPro:IPR006114"
                     /db_xref="InterPro:IPR006115"
                     /db_xref="InterPro:IPR006183"
                     /db_xref="InterPro:IPR006184"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="InterPro:IPR012284"
                     /db_xref="InterPro:IPR013328"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/Swiss-Prot:P14062"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA
                     ENPGKKLVPYYTV"
BASE COUNT     6284 a   4028 c   5152 g   6616 t
ORIGIN
        1 gaattcggga ggcgcaatga aagtcagctt ttttctgctg aaatttccac tctcatcgga
       61 aacctttgtg ctgaatcaga ttactgcgtt tattgatatg ggccatgagg tggagattgt
      121 cgcgttacaa aaaggcgata cccaacatac tcacgccgcc tgggagaagt atggcctggc
      181 ggcgaaaacc cgctggttac aggatgagcc ccagggacgg ctggcgaaac tgcgctaccg
      241 ggcatgtaaa acgctgccgg ggctgcatcg ggcggcgacc tggaaagcgc tcaattttac
      301 ccgctatggc gatgaatcac gcaatttgat cctttccgcg atttgcgcgc aggtgagcca
      361 gccttttgtg gcggatgtgt ttatcgcaca ctttggtccg gcgggcgtga cggcggccaa
      421 actacgcgaa ctgggcgtgc ttcgcggcaa aatcgcgact attttccacg ggattgatat
      481 ctctagtcgt gaggtgctca gtcattacac gccggagtat cagcagttgt ttcgtcgtgg
      541 cgatctgatg ctgcccatca gcgatctgtg ggccggtcgc ctgaaaagta tgggctgtcc
      601 gccggaaaag attgccgttt cgcgcatggg cgtcgacatg acgcgtttta cccatcgttc
      661 ggtgaaagcg ccagggatgc cgctggagat gatttccgtc gcgcgcctga cagaaaaaaa
      721 aggcctgcat gtggcgattg aagcctgtcg gcaactgaaa gcacagggcg tggcgtttcg
      781 ctaccgcatt ctggggattg gcccgtggga acgtcggctg cgcacgctca tcgagcagta
      841 tcagctagag gatgtcattg agatgccggg gtttaaaccg agccatgaag tgaaggcgat
      901 gctggatgac gccgatgttt ttttgctgcc gtcgattacc ggtacggatg gcgatatgga
      961 aggtattccg gtagcgctga tggaggcgat ggcggtaggg attcccgtgg tatctaccgt
     1021 gcatagcggt attccggaac tggtggaggc cggcaaatcc ggctggctgg tgccggaaaa
     1081 cgatgcgcag gcgctggcgg cccgactcgc tgagttcagc cggattgacc acgacacgct
     1141 ggagtcggtg atcacgcgcg cccgtgaaaa agtggcgcaa gattttaatc agcaggcgat
     1201 taatcgccag ttagccagcc tgctacaaac gatataaacg aggtggtatg cccgcgacta
     1261 aattctcccg acgtaccctc ctgacggcag gttctgcgct tgctgttctt ccttttctgc
     1321 gcgccttgcc ggtacaggcg cgtgaacctc gcgagaccgt cgatattaag gattatccgg
     1381 cggatgacgg tatcgcctcg ttcaaacagg ccttcgccga cggacagacc gtggtcgtac
     1441 cgccaggatg ggtgtgtgaa aatatcaatg cggcgataac gattccggcg ggaaaaacgc
     1501 tgcgggtaca gggcgcggtg cgtgggaatg gccggggacg gtttattttg caggacgggt
     1561 gtcaggtggt gggggagcag ggcggcagtc tgcacaatgt gacgctggat gttcgcgggt
     1621 cggactgtgt gattaaaggc gtggcgatga gcggctttgg ccccgtcgcg caaattttca
     1681 tcggtggtaa ggaaccgcag gtgatgcgta atctcattat cgatgacatc accgttaccc
     1741 acgccaacta cgccattctc cgccagggat ttcataacca aatggatggc gcgcggatta
     1801 cgcatagccg ctttagcgat ttacaggggg acgccattga gtggaatgtc gcgattcacg
     1861 accgcgacat cctgatttcc gatcatgtca tcgaacgcat taattgtacc aatggcaaaa
     1921 tcaactgggg gatcggcatc gggctggcgg gtagcaccta tgacaacagt tatcctgaag
     1981 accaggcagt aaaaaacttt gtggtggcca atattaccgg atctgattgc cgacagcttg
     2041 tgcacgtaga aaatggcaaa catttcgtca ttcgcaatgt caaagccaaa aacatcacgc
     2101 ccggtttcag taaaaatgcg ggtattgata acgcaacgat cgcaatttat ggctgtgata
     2161 atttcgtcat tgataatatt gatatgacga atagtgccgg gatgctcatc ggctatggcg
     2221 tcgttaaagg aaaatacctg tcaattccgc aaaactttaa attaaacgct attcggttgg
     2281 ataatcgcca ggttgcttat aaattacgcg gcattcaaat ttcctccggc aacaccccct
     2341 cttttgtcgc catcaccaat gtacggatga cgcgtgctac gctggaactg cataatcaac
     2401 cgcagcacct ctttctgcgc aatatcaacg tgatgcaaac ttcagcgatt ggcccggcgt
     2461 taaaaatgca tttcgatttg cgtaaagatg tacgtggtca atttatggcc cgccaggaca
     2521 cgctgctttc cctcgctaat gttcatgcca tcaatgaaaa cgggcagagt tccgtggata
     2581 tcgacaggat taatcaccaa accgtgaatg tcgaagcagt gaatttttcg ctgccgaagc
     2641 ggggagggta agtaccgcta tttttacgaa aattcctggg aaaaagttgt tcatacttaa
     2701 tgttatggtg ccgactaaga cgtaatgtag agcgtgccat cattatccct ggcagcagag
     2761 taattcatgc tggcgaaaac aagctaaaga gctataattc agcaaccatt ttacaggtgg
     2821 aagaaacaat gatgaatttg aaagcagtta taccggtagc gggtttgggt atgcatatgt
     2881 tgcctgccac caaggcaatc ccaaaagaga tgctaccgat cgtcgacaag ccaatgattc
     2941 agtacattgt cgatgagatt gtggctgcag ggatcaaaga aatcgtgctg gtgactcacg
     3001 cgtctaaaaa cgccgttgag aaccacttcg acacctctta tgaacttgaa tcacttcttg
     3061 agcagcgcgt taagcgtcag cttttggcgg aagtgcaatc tatctgccca ccgggcgtga
     3121 cgattatgaa cgttcgccag gcgcagccgt tagggctggg gcattctatt ctgtgcgcgc
     3181 gtccggtcgt gggcgataac cctttcattg tggtactccc ggatattatt atcgatgatg
     3241 ctaccgccga tccgctgcgc tataaccttg cggcgatggt ggcgcgtttc aatgaaacgg
     3301 gtcgcagcca ggtgctggcg aagcgcatga aaggtgattt atcggagtat tccgttatcc
     3361 agacgaaaga acctctggat aatgaaggca aagtcagccg gattgtggag tttatcgaaa
     3421 aaccggatca gccgcagacg ctggattccg atttgatggc ggtaggccgt tatgtgcttt
     3481 cagccgacat ctgggcggaa ctggaaagaa ccgaaccggg cgcctggggc cgcatccagc
     3541 tcaccgatgc cattgctgaa ctggcgaaaa aacagtcggt tgacgcgatg ctaatgacgg
     3601 gtgacagcta tgactgcggt aaaaaaatgg gctacatgca ggcatttgtg aagtacgggc
     3661 tgcgcaacct gaaagaagga gccaagttcc gtaagagcat agagcagctt ttgcatgaat
     3721 aagtattaac aaccgtgata aatggttggt gataaacata ataacggcag tgaacattcg
     3781 aagcggcaag ttggctgaaa cgagtgttga ctgccgtttt agttttgtat aaagggctta
     3841 agtaacaagg ggttatctgg agcattttaa tgctgatttt ataagattaa tccttgtttc
     3901 cggatgcaat taataagaca attagcgttt aagttttagt gagctttgcc ctgctgggcg
     3961 aggtttgcaa caagtcgata tgtacgcagt gcactggtag ctgatgagcc aggggcggta
     4021 gcgtgtgtaa cgacttgagc aattaatttt tattggcaaa ttaaatacca cattaaatac
     4081 gccttatgga atagaaaagt gaagatactt attactggcg gggcaggttt tattggatca
     4141 gctgttgtcc gccatattat taagaataca caggacactg tagttaatat tgataaatta
     4201 acctacgccg gtaatcttga atccctttct gatatttctg aaagtaatcg ctacaatttt
     4261 gaacacgcgg atatttgtga ttccgctgaa ataacgcgta tttttgagca gtaccagccg
     4321 gacgcggtga tgcatttggc tgcggaaagt catgtggacc gttcgattac cgggccagca
     4381 gcatttattg aaaccaatat cgtcggcacc tatgcacttc ttgaagttgc gcgtaaatac
     4441 tggtctgccc ttggcgaaga taaaaaaaat aattttcgtt ttcatcatat ttccactgat
     4501 gaagtttacg gcgatttacc gcatcctgat gaagttgaaa acagcgttac gctgccgtta
     4561 tttactgaaa cgacggcata tgcgccaagt agcccctatt ctgcgtcaaa agcatccagc
     4621 gatcatttag tccgtgcctg gcggcgtacc tatggtctac caacgatcgt taccaattgt
     4681 tctaataact atggccctta tcacttccct gaaaaactga ttccgttggt cattttgaac
     4741 gcactggaag gaaagccttt gccaatttat ggcaaagggg atcagattcg cgattggcta
     4801 tatgtagaag atcatgctcg cgcgcttcat atggtagtga ctgaaggcaa ggcaggggag
     4861 acttataaca ttggtggaca caatgagaag aaaaatctcg atgtggtatt taccatctgt
     4921 gatctgctgg atgagattgt acccaaagcg acttcttatc gtgaacaaat cacttatgtc
     4981 gcggatcgtc cgggccatga tcgtcgttat gccattgatg caggtaaaat tagccgcgaa
     5041 ttaggctgga aaccgctgga gacctttgaa agcggtattc gtaaaacagt ggaatggtac
     5101 cttgcaaata ctcaatgggt aaacaatgtt aaaagtgggg cgtatcagag ttggatagaa
     5161 cagaactatg aaggacgcca gtaatgaata tcttactttt tggtaagaca gggcaagtag
     5221 gctgggagtt gcaacgttct ctggcaccgg tagggaatct gattgccctg gatgtccatt
     5281 caaaagagtt ttgcggtgat tttagtaatc cgaaaggcgt tgccgaaacc gttcgtaagc
     5341 ttcgtcccga tgtgattgtt aacgcagcag cccatactgc agtagataaa gcagagtctg
     5401 aaccagaact ggcgcagtta cttaacgcca ccagtgtgga agccatcgct aaagcagcca
     5461 acgaaactgg cgcatgggta gtgcattatt caaccgatta tgtatttcct ggtaccggcg
     5521 atatcccatg gcaggaaacg gacgctacgt cgccgctgaa tgtctatggc aaaaccaaac
     5581 tggcgggaga aaaggccctg caggataact gccctaaaca ccttatcttc cgcaccagtt
     5641 gggtttatgc aggtaagggc aataatttcg caaagacaat gcttcgtctg gcgaaagagc
     5701 gtcagacact ttcagtcatt aacgatcagt acggtgcgcc aaccggtgcg gaattactgg
     5761 ctgactgtac ggcgcatgcg atccgtgtgg cgttaaataa accagaagtc gcaggtcttt
     5821 accatctggt tgccggggga accacaacct ggcatgacta cgcggcctta gtctttgacg
     5881 aggcgcgcaa agcagggata acgcttgcgc tgactgagct taatgctgtg ccgaccagcg
     5941 cctacccgac gccggcgagc agaccaggca attcgcgtct caatactgaa aagtttcagc
     6001 gtaattttga ccttattctg cctcaatggg aattaggagt taagcgtatg ctgactgaaa
     6061 tgtttacgac gacaaccatc taataaattt aaatgcccat cagggcattt tctatgaatg
     6121 agaaatggaa atgaaaacgc gtaagggcat tattttagcg gggggctccg gcacccgtct
     6181 ttatccggtg accatggcgg taagtaagca attgctacca atttatgata aaccgatgat
     6241 ttactatccc ctttccacgc ttatgctggc aggcattcgg gatatcctga tcatcagtac
     6301 gccacaggac acgccgcgtt ttcaacaact gctgggagac ggcagccagt gggggctgaa
     6361 tcttcaatat aaagtacagc caagcccgga tggcttagca caggcgttta ttattggtga
     6421 agagttcatt ggtcatgatg attgtgcatt agtgctgggt gacaatatct tctatggtca
     6481 tgatttacca aagttaatgg aagctgccgt taataaagaa agtggtgcta ccgtcttcgc
     6541 ttatcatgta aacgatccgg agcgctacgg tgtggttgag tttgaccaaa agggcacagc
     6601 cgttagtctg gaagaaaaac cattacaacc gaagagtaat tacgcggtaa cggggctgta
     6661 tttttatgat aatagcgtgg tggagatggc gaaaaatctt aagccttccg ctcgcggtga
     6721 gttagaaatc acggatatta accgtatcta tatggagcag ggaagattgt ctgtcgctat
     6781 gatggggcgc ggttatgcct ggctggatac agggacgcat cagagtttga tagaggccag
     6841 taattttatt gcaaccatcg aagaacgcca ggggctaaaa gtgtcctgcc cggaagagat
     6901 cgcatttcgt aaaaatttta taaatgcaca acaggttata gaactggccg ggccattatc
     6961 aaaaaatgat tatggcaaat atttgctgaa gatggtgaaa ggtttataag tgatgattgt
     7021 gattaaaaca gcaataccag atgtcttgat cttagagcct aaagtttttg gcgatgagag
     7081 gggattcttt tttgaaagtt ataaccagca gacctttgaa gagttgattg gacgtaaagt
     7141 tacatttgtt caagataatc attcaaaatc caaaaagaac gtactcagag ggctacattt
     7201 tcagagagga gaaaatgcac aggggaagtt agttcgttgt gctgtcggtg aggtttttga
     7261 tgttgcggtc gatatccgaa aagaatcgcc tacttttggt caatgggttg gtgtaaatct
     7321 gtctgctgag aataagcgac agctttggat tccagaaggt tttgctcatg gttttgttac
     7381 tcttagtgag tatgcagagt ttctgtacaa agcaactaat tattactcac cttcatcgga
     7441 aggtagcatt ctatggaatg atgaggcaat aggtattgaa tggccttttt ctcagctgcc
     7501 tgagctttca gcaaaagatg ctgcagcacc tttactggat caagccttgt taacagagta
     7561 agcatcgtgt ctcatattat taagattttt ccatcaaata ttgaattttc cggtagagag
     7621 gatgaatcaa tcctcgatgc tgcgctatcg gctggtatcc atcttgaaca tagctgcaaa
     7681 gcgggtgatt gtggtatctg tgagtccgat ttgttggcgg gagaagttgt tgactccaaa
     7741 ggtaatattt ttggacaggg tgataaaata ctaacctgct gctgtaaacc taaaaccgcc
     7801 cttgagctaa atgcgcattt ttttcctgaa ctagctggac agacaaaaaa aattgtccca
     7861 tgcaaggtaa atagtgctgt actggtttca ggcgatgtta tgactttgaa gttacgcaca
     7921 ccaccaacag caaaaattgg cttccttcca gggcagtata tcaatttaca ttataaaggt
     7981 gtaactcgca gttattctat cgctaatagt gatgagtcga atggtattga gttgcatgta
     8041 aggaatgttc ccaatggtca gatgagttcg ctcatttttg gggagttaca agaaaatact
     8101 cttatgcgca ttgaagggcc ttgcggaaca ttttttattc gtgaaagtga cagacctata
     8161 atcttccttg caggcggtac tggattcgct ccagttaaat caatggttga gcatctcatt
     8221 cagggaaaat gtcgtcgtga gatctacatt tactggggaa tgcaatatag taaagatttt
     8281 tactctgcat taccgcagca gtggagtgaa cagcacgaca acgttcatta tatccctgtt
     8341 gtttctggtg atgacgccga atggggggga agaaagggat ttgtccatca tgccgtgatg
     8401 gatgattttg attctctaga gttcttcgat atatatgcat gtggttcacc tgtgatgatc
     8461 gatgccagta aaaaggactt tatgatgaaa aatctctctg tagaacattt ctattctgat
     8521 gcatttaccg catctaataa tattgaggat aatttatgaa agcggtcatc ctggctggtg
     8581 gacttggtac cagactaagt gaagaaacaa ttgtaaaacc aaaaccgatg gtagaaattg
     8641 gtggcaagcc tattctttgg cacattatga aaatgtattc tgtgcatggt atcaaggatt
     8701 ttattatctg ctgtggttat aaaggatatg tgattaaaga atattttgcg aactacttcc
     8761 ttcacatgtc agatgtaaca ttccatatgg ctgaaaaccg tatggaagtt caccataaac
     8821 gtgttgaacc atggaatgtc acattggttg atacgggtga ttcttcaatg actggtggtc
     8881 gtctgaaacg tgttgctgaa tacgtaaaag atgacgaggc tttcctgttt acttatggtg
     8941 atggcgttgc cgaccttgat atcaaagcga ctatcgattt ccataaggct cacggtaaga
     9001 aagcgacttt aacagctact tttccaccag gacgctttgg cgcattagat atccgagctg
     9061 gtcaggtccg gtcattccag gaaaaaccga aaggcgatgg ggcaatgatc aatggtggtt
     9121 tctttgtgtt gaatccatcg gttatcgatc tcatcgataa cgatgcaaca acctgggaac
     9181 aagagccatt aatgacattg gcacaacagg gggagttaat ggcttttgaa cacccaggtt
     9241 tctggcagcc gatggatacc ctacgtgata aagtttacct cgaagggctg tgggaaaaag
     9301 gtaaagctcc gtggaaaacc tgggagtaac tagatgattg ataaaaattt ttggcaaggt
     9361 aaacgtgtat tcgttaccgg ccatactggc tttaaaggaa gctggctttc gctatggctg
     9421 actgaaatgg gtgcaattgt aaaaggctat gcacttgatg cgccaactgt tccaagttta
     9481 tttgagatag tgcgtcttaa tgatcttatg gaatctcata ttggcgacat tcgtgatttt
     9541 gaaaagctgc gcaattctat tgcagaattt aagccagaaa ttgttttcca tatggcagcc
     9601 cagcctttag tgcgcctatc ttatgaacag ccaatcgaaa catactcaac aaatgttatg
     9661 ggtactgtcc atttgcttga aacagttaag caagtaggta acataaaggc agtcgtaaat
     9721 atcaccagtg ataagtgcta cgacaatcgt gagtgggtgt ggggctatcg tgagaacgaa
     9781 cccatgggag ggtacgatcc atactctaat agtaaaggtt gtgcagaatt agtcgcgtct
     9841 gcattccgga actcattctt caatcctgca aattatgagc aacatggcgt tggtttggcg
     9901 tctgtgaggg ctggtaatgt cataggcgga ggcgattggg ctaaagaccg tttaattccc
     9961 gatattctgc gctcatttga aaataaccag caggttatta ttcgaaaccc atattctatc
    10021 cgtccctggc agcatgtact ggagcctctt tctggttaca ttgtggtggc gcaacgctta
    10081 tatacagaag gtgctaagtt ttctgaagga tggaatttcg gcccgcgtga tgaagatgcg
    10141 aagacggtcg aatttattgt tgacaagatg gtcacgcttt ggggtgatga tgcaagctgg
    10201 ttactggatg gtgagaatca tcctcatgag gcacattacc tgaaactgga ttgctctaaa
    10261 gcaaatatgc aattaggatg gcatccgcgt tggggattga ctgaaacact tggtcgcatc
    10321 gtaaaatggc ataaagcatg gattcgcggc gaagatatgt tgatttgttc aaagcgtgaa
    10381 atcagcgact atatgtctgc aactactcgt taagaaaata agtttaagga atcaaagtaa
    10441 tgacagcaaa taacctgcgt gagcaaatct ctcagcttgt cgctcagtat gcgaatgagg
    10501 cattgagccc gaaacctttt gttgcaggta caagcgttgt gcctccttcc gggaaggtta
    10561 ttggtgccaa agagttacaa ttgatggttg aggcgtctct tgatggatgg ctaactactg
    10621 gtcgtttcaa tgatgccttt gaaaaaaaac ttggggaatt tattggggtt cctcatgttt
    10681 taacgacaac atctggctct tcggcaaact tgctggcact gactgcgctg acttccccaa
    10741 aattaggcga gcgagctctc aaacctggtg atgaggttat tactgtcgct gctggcttcc
    10801 cgactacagt taacccggcg atccagaatg gtttaatacc ggtattcgtg gatgttgata
    10861 tcccgacata taatatcgat gcctctctca ttgaagctgc agttactgag aaatcaaaag
    10921 cgataatgat cgctcataca ctcggtaatg catttaacct gagtgaagtt cgtcggattg
    10981 ccgataaata taacttatgg ttgattgaag actgctgtga tgcccttggg acgacttatg
    11041 aaggccagat ggtaggtacc tttggtgaca tcggaaccgt tagtttttat ccggctcacc
    11101 atatcacaat gggtgaaggc ggtgctgtat tcaccaagtc aggtgaactg aagaaaatta
    11161 ttgagtcgtt ccgtgactgg ggccgggatt gttattgtgc gccaggatgc gataacacct
    11221 gcggtaaacg ttttggtcag caattgggat cacttcctca aggctatgat cacaaatata
    11281 cttattccca cctcggatat aatctcaaaa tcacggacat gcaggcagca tgtggtctgg
    11341 ctcagttgga gcgcgtagaa gagtttgtag agcagcgtaa agctaacttt tcctatctga
    11401 aacagggctt gcaatcttgc actgaattcc tcgaattacc agaagcaaca gagaaatcag
    11461 atccatcctg gtttggcttc cctatcaccc tgaaagaaac tagcggtgtt aaccgtgtcg
    11521 aactggtgaa attccttgat gaagcaaaaa tcggtacacg tttactgttt gctggaaatc
    11581 tgattcgcca accgtatttt gctaatgtga aatatcgtgt agtgggtgag ttgacaaata
    11641 ccgaccgtat aatgaatcaa acgttctgga ttggtattta tccaggcttg actacagagc
    11701 atttagatta tgtagttagc aagtttgaag agttctttgg tttgaatttc taattcaatt
    11761 tattctatct ggtgattgcg atgacctttt tgaaagaata tgtaattgtc agtggggctt
    11821 ccggctttat tggtaagcat ttactcgaag cgctaaaaaa atcggggatt tcagttgtcg
    11881 caatcactcg agatgtaata aaaaataata gtaatgcatt agctaatgtt agatggtgca
    11941 gttgggataa tatcgaatta ttagtcgagg agttatcaat tgattctgca ttaattggta
    12001 tcattcattt ggcaacagaa tatgggcata aaacatcatc tctcataaat attgaagatg
    12061 caaatgttat aaaaccatta aagcttcttg atttggcaat aaaatatcgg gcggatatct
    12121 ttttaaatac agatagtttt tttgccaaga aagattttaa ttatcaacat atgcggcctt
    12181 atataattac taaaagacac tttgatgaaa ttgggcatta ttatgctaat atgcatgaca
    12241 tttcatttgt aaacatgcga ttagagcatg tatatgggcc tggggatggt gaaaataaat
    12301 ttattccata cattatcgac tgcttaaata aaaaacagag ttgcgtgaaa tgtacaacag
    12361 gcgaacagat aagagacttt atttttgtag atgatgtggt aaatgcttat ttaactatat
    12421 tagaaaatag aaaagaagta ccttcatata ctgagtatca agttggaact ggtgctgggg
    12481 taagtttgaa agattttctg gtttatttgc aaaatactat gatgccaggt tcatcgagta
    12541 tatttgaatt tggtgcgata gagcaaagag ataatgaaat aatgttctct gtagcaaata
    12601 ataaaaattt aaaagcaatg ggctggaaac caaatttcga ttataaaaaa ggaattgaag
    12661 aactactgaa acggttatga gattttcatg atcttttaat aaataaatcg ttaacaaatt
    12721 agtcgcgtta tgttgtaaaa actaagtcgt ttaattgcat agtgaaagtt caattgttaa
    12781 aaattccgag tcatttaatt gttgcaggtt catcatggtt atccaaaata ataattgccg
    12841 gggtgcagtt agcaagtatt tcatatctta tttctatgct aggtgaagag aaatatgcaa
    12901 tctttagttt gttaactggt ttattagtat ggtgtagcgc tgttgatttt ggcataggta
    12961 caggactgca aaattatata tcagaatgca gagccaaaaa caaaagttat gatgcatata
    13021 ttaaatcagc attacatcta agctttatag ctattatttt ttttattgct ttattttata
    13081 ttttttctgg ggtaatttcc gctaaatatc tttcttcttt tcatgaggta ttacaggaca
    13141 aaaccagaat gctctttttt acctcatgtc tggttttcag ttctattgga atcggagcta
    13201 ttgcttataa aatacttttt gccgaattgg tcgggtggaa agctaatcta ttaaacgcat
    13261 tatcttatat gataggtatg ctcggcttgc tatatatata ctataggggg atctcagttg
    13321 acataaaatt atcactaata gtcctgtatc ttccagtggg tatgatttca ttgtgctata
    13381 ttgtatatag atacataaag ctttatcatg ttaaaacaac aaaatctcat tatatagcaa
    13441 ttttacgtag atcttcaggg ttttttcttt ttactttatt atcgatagtg gtgcttcaaa
    13501 cagattatat ggtcatttct caaaggctaa ctcctgctga tattgttcaa tatacagtaa
    13561 cgatgaaaat ttttggttta gtctttttta tttatactgc tattttgcaa gcattatggc
    13621 ctatatgtgc tgaattgaga gtcaaacagc aatggaaaaa acttaacaaa atgataggtg
    13681 tcaatatttt gcttggctca ctatatgttg ttggatgtac aatatttatt tatttattta
    13741 aagaacagat attttcagta atagccaaag atattaatta tcaagtttct attttatctt
    13801 ttatgttaat tggcatatat ttctgtattc gcgtttggtg tgacacttat gcaatgttat
    13861 tgcaaagtat gaattattta aaaatacttt ggatattagt accactacaa gcaataattg
    13921 gtggaatagc acaatggtat ttttctagta cgcttggaat cagtggagtg ctgcttggct
    13981 tgattatatc ttttgcttta actgtttttt gggggcttcc actaacttac ttaattaagg
    14041 caaataaggg ataatcatat gcttatatca ttttgtattc caacttataa tagaaaacaa
    14101 tatcttgaag agttgttgaa tagtataaat aatcaggaaa aatttaattt agatattgag
    14161 atatgtatat cagataatgc ctctactgat ggtacagagg aaatgattga tgtttggagg
    14221 aacaattata atttcccaat aatatatcgg cgtaatagcg ttaaccttgg gccagatagg
    14281 aattttcttg cttcagtatc ccttgcgaat ggggattatt gttggatatt tggcagtgat
    14341 gatgctcttg cgaaagactc gttagcgata ttacaaactt atctcgattc tcaagcagat
    14401 atatatttat gtgacagaaa agagaccggg tgtgatttag ttgagattag aaaccctcat
    14461 cgttcttggc tcagaacaga tgatgaactt tatgtgttta ataataattt agatagggaa
    14521 atctatctca gtagatgctt atctattggt ggtgtattta gctatctaag ttctttaata
    14581 gtaaaaaaag aacgatggga tgccattgat tttgatgcgt cctatattgg cacttcctat
    14641 cctcatgtat ttatcatgat gagcgtattt aatacgccag ggtgcctttt gcattatata
    14701 tcaaaaccac tcgtaatatg ccgaggagat aatgatagtt tcgagaagaa aggaaaggcc
    14761 agacgaattt taattgattt tattgcatat ttaaaattag ctaatgattt ttacagtaaa
    14821 aatatatctt taaaacgagc atttgaaaat gttttgctaa aagagagacc atggttatat
    14881 acaactttgg ctatggcatg ttatggcaat agtgatgaaa aaagagattt atctgaattt
    14941 tatgcaaagc taggttgtaa taaaaatatg atcaacactg tacttcgatt tgggaaacta
    15001 gcatatgcag tgaaaaatat taccgtgctt aagaatttta ctaaacggat aattaagtag
    15061 tagtaagtta ttatattgag attaaatgta gatttaacct ttctggattc agctagattt
    15121 acgttactga cttttctttt taatgaaaat catatttgat atatataaat aaatttggat
    15181 agcttaacta cttagatgtt tttttctggg aatgttagta taataatata tttctttatg
    15241 attgtttttg tagtgtttta ctgccggtat tacattaact ctattattaa gaattacacc
    15301 tagtgtaagc ttcgtaatat tatttatcct tatgattatt gctttaaaga tgcgtatgga
    15361 aaaacggaga gctattcaat gatcgtaaac ctatcacgtt taggtaaaag tggtacggga
    15421 atgtggcaat actcgattaa atttttaacg gcactgcgag aaatagctga tgttgacgca
    15481 ataatctgta gcaaggtaca cgctgattat tttgaaaagc tcggttatgc agtagttact
    15541 gttccgaata ttgttagcaa cacatcaaaa acatcgcgac ttagaccatt agtatggtat
    15601 gtatatagtt actggcttgc gctgagggtt ttaattaagt ttggtaataa aaaattggtg
    15661 tgtactacac atcacactat ccccttactg agaaaccaaa cgataaccgt acatgatata
    15721 agaccttttt attatccaga tagttttatt cagaaagtgt attttcgctt tttattaaaa
    15781 atgtccgtta agcgatgtaa gcatgtttta acggtatctt ataccgttaa agatagcatt
    15841 gctaaaactt ataatgtaga tagtgagaaa atatcagtaa tttataatag tgttaataaa
    15901 tctgatttta tacaaaaaaa agaaaaagag aattactttt tagctgttgg tgcaagttgg
    15961 ccacataaaa atattcattc attcataaaa aataaaaaag tttggtctga ctcttataat
    16021 ttaattattg tatgtggtcg tactgactat gcaatgtctc tccaacaaat ggtcgttgat
    16081 ctggaactaa aagataaagt gactttttta catgaagtct catttaatga attaaagatt
    16141 ttatattcta aagcctacgc gcttgtttat ccatctattg atgagggttt tggtatacct
    16201 cctattgaag cgatggcatc aaatactcca gttatagtgt ccgatatacc agtatttcat
    16261 gaagtgttaa ccaatggtgc attatatgtg aatccggatg atgaaaaaag ctggcagagt
    16321 gcaattaaaa atatagagca gttgcctgat gcaatttccc gatttaacaa ctatgtcgca
    16381 cggtatgact ttgataatat gaagcagatg gttggcaatt ggttggcgga atcaaaataa
    16441 atgaaaataa cattaattat tcccacatat aatgcagggt cgctttggcc taatgttctg
    16501 gatgcgatta agcagcaaac tatatatccg gataaattga ttgttataga ctcaggttct
    16561 aaagatgaaa cggttccgtt agcctcagac ctgaaaaata tatcaatatt taatattgac
    16621 tctaaagatt ttaatcatgg aggaaccaga aatttagcag ttgcaaaaac tctggacgct
    16681 gatgttataa tttttctaac gcaagatgca attctcgcgg attcggatgc aattaaaaat
    16741 ttggtttatt atttttcaga tccattgata gcagcggttt gtggtagaca acttcctcat
    16801 aaagatgcta atccccttgc agtgcatgcc agaaatttta attatagttc aaaatctatt
    16861 gttaaaagta aggcagatat agaaaaattg ggtattaaaa ctgtatttat gtccaattct
    16921 tttgctgcct atcgccgttc cgtttttgaa gagttaagtg ggtttcctga acatacaatt
    16981 cttgccgagg atatgtttat ggcggctaag atgattcagg cgggttataa ggtcgcctac
    17041 tgcgctgaag cggtggtaag acactcccat aattataccc cgcgagaaga gtttcaacga
    17101 tattttgata ctggtgtatt tcatgcttgt tctccgtgga ttcagcgtga ctttggcgga
    17161 gccggtggtg agggtttccg cttcgtaaaa tcagagattc aattcctgct taaaaatgca
    17221 ccgttctgga ttccaagagc tttattaaca acctttgcta aattcttggg ttacaaatta
    17281 ggcaagcatt ggcaatcttt accgttgtct acatgtcgct attttagcat gtacaagagt
    17341 tattggaata atatccaata ttcttcgtca aaagagataa aataaatgtc ttttcttccc
    17401 gtaattatgg ctggcggcac aggtagccgt ttatggccgc tttcacgcga atatcatccg
    17461 aagcagtttc taagcgttga aggtaaacta tcaatgctgc aaaatactat aaagcgatta
    17521 gcttcacttt ctacagaaga acccgttgtc atttgcaatg acagacaccg tttcttagtc
    17581 gctgaacaac tccgtgaaat tgacaagtta gcaaataata ttattctcga accggtaggc
    17641 cgtaatactg caccagcgat cgctcttgcc gcgttttgtg cgctccagaa tgctgataat
    17701 gctgatcctc ttttgttggt tcttgctgca gatcatgtga ttcaggatga aatagctttt
    17761 acgaaagctg tcagacatgc tgaagaatac gctgcaaatg gtaagcttgt aacttttggt
    17821 attgttccaa cgcatgctga aacgggttat ggatatattc gtcgtggtga gttgatagga
    17881 aatgacgctt atgcagtggc tgaatttgtg gagaaaccgg atatcgatac cgccggtgac
    17941 tatttcaaat cagggaaata ttactggaat agcggtatgt ttttatttcg tgcaagctct
    18001 tatttaaacg aattaaagta tttatcacct gaaatttata aagcttgtga aaaggcggta
    18061 ggacatataa atcccgatct tgattttatt cgtattgata aagaagagtt tatgtcatgc
    18121 ccgagtgatt ctatcgatta tgcagttatg gagcacacac agcatgcggt ggtgatacca
    18181 atgagcgctg gctggtcgga tgtgggttcc tggtcctcac tttgggatat atcgaataaa
    18241 gatcatcaga gaaatgtttt aaaaggagat attttcgcac atgcttgtaa tgataattac
    18301 atttattccg aagatatgtt tataagtgcg attggtgtaa gcaatcttgt cattgttcaa
    18361 acaacagacg ctttactggt ggctaataaa gatacagtac aagatgttaa aaaaattgtc
    18421 gattatttaa aacggaatga taggaacgaa tataaacaac atcaagaagt tttccgcccc
    18481 tggggaaaat ataatgtgat tgatagcggc aaaaattacc tcgttcgatg tatcactgtt
    18541 aagccgggtg agaaatttgt ggcgcagatg catcaccacc gggctgagca ttggatagta
    18601 ttatccggga ctgctcgtgt tacaaaggga gagcagactt atatggtttc tgaaaatgaa
    18661 tcaacattta ttcctccgaa tactattcac gcgctggaaa atcctggaat gacccccctg
    18721 aagttaattg agattcaatc aggtacctat cttggtgagg atgatattat tcgtttagaa
    18781 caacgttctg gattttcgaa ggagtggact aatgaacgta gttaataata gccgtgatgt
    18841 tatttattca tcaggtattg tgtttggaac gagtggggct cgcggtcttg taaaagattt
    18901 tacacctcag gtatgtgctg cttttacggt ttcatttgtt gccgttatgc aggaacattt
    18961 ttcctttgat accgtagcat tggcaataga taatcgtcca agtagttatg ggatggctca
    19021 ggcgtgtgct gctgcattgg cggataaagg cgttaactgt attttttatg gagtggtacc
    19081 aaccccagct ttggcctttc agtctatgtc tgacaatatg cctgcgataa tggttacggg
    19141 aagtcatatt ccattcgagc ggaacggcct caagttttat cgtcctgatg gtgaaatcac
    19201 gaaacatgat gaggctgcga tccttagtgt tgaagatacg tgcagccatt tagagcttaa
    19261 agaactcata gtttcagaaa tggctgctgt taattatata tctcgttata catctttatt
    19321 ttctactcca ttcctgaaaa ataagcgtat tggtatttac gaacattcaa gcgctgggcg
    19381 tgatctttat aagcctttat ttattgcatt gggggctgaa gtcgttagct tgggtagaag
    19441 cgataatttt gtacctatag atacagaggc tgtaagcaaa gaggatcggg aaaaagctcg
    19501 ctcatgggct aaagagttcg atttagatgc catattctcg acagatgggg atggtgatcg
    19561 ccctcttatt gctgatgagg ccggtgagtg gctaagaggc gatatactag gtctattatg
    19621 ttcacttgca ttggatgcag aagccgtcgc tattcctgtt agttgtaaca gcataatttc
    19681 ttctggccgc ttttttaaac atgttaagct tacaaaaatt ggctcgcctt atgttatcga
    19741 agcttttaat gaattatcgc ggagttatag tcgtattgtc ggttttgaag ccaatggcgg
    19801 ttttttatta ggaagcgaca tctgtattaa cgagcagaat cttcatgcct taccaactcg
    19861 tgatgctgta ttaccagcaa taatgctgct ttacaaaagt aggaatacca gcattagcgc
    19921 tttagtcaat gaactcccaa ctcgttacac ccattctgac agattacagg ggattacaac
    19981 tgataaaagt caatccttaa ttagtatggg cagagaaaat ctgagcaacc tcttaagcta
    20041 tattggtttg gagaatgaag gtgcaatttc tacagatatg acagatggta tgcgaattac
    20101 tttacgtgat ggatgtattg tgcatttgcg cgcttctggt aatgcacctg agttacgctg
    20161 ctatgcagaa gctaatttat taaatagggc tcaggatctt gtaaatacaa cgcttgctaa
    20221 tattaaaaaa cgatgcttgc tgtaaaaaaa ttgaatgtta tttacttaat atgcctattt
    20281 tatttacatt atgcacggtc agagggtgag gattaaatgg ataatattga taataagtat
    20341 aatccacagc tatgtaaaat ttttttggct atatcggatt tgattttttt taatttagcc
    20401 ttatggtttt cattaggatg tgtctatttt atttttgatc aagtacagcg atttattcct
    20461 caagaccaat tagatacaag agttattacg cattttattt tgtcagtagt atgtgtcggt
    20521 tggttttgga ttcgtttgcg acattatact atccgcaagc cattttggta tgagttaaaa
    20581 gaaatttttc gtacgatcgt tatttttgct atatttgatt tggctctgat agcgtttaca
    20641 aaatggcagt tttcacgcta tgtctgggtg ttttgttgga cttttgccct aatcctggtg
    20701 cctttttttc gcgcacttac aaagcattta ttgaacaagc taggtatctg gaagaaaaaa
    20761 actatcatcc tggggagcgg acagaatgct cgtggtgcat attctgcgct gcaaagtgag
    20821 gagatgatgg ggtttgatgt tatcgctttt tttgatacgg atgcgtcaga tgctgaaata
    20881 aatatgttgc cggtgataaa ggatactgag attatttggg atttaaatcg tacaggtgat
    20941 gtccattata tccttgctta tgaatacacc gagttggaga aaacacattt ttggctacgt
    21001 gaactttcaa aacatcattg tcgttctgtt actgtagtcc cctcgtttag aggattgcca
    21061 ttatataata ctgatatgtc ttttatcttt agccatgaag ttatgttatt aaggatacaa
    21121 aataacttgg ctaaaaggtc gtcccgtttt ctcaaacgga catttgatat tgtttgttca
    21181 ataatgattc ttataattgc atcaccactt atgatttatc tgtggtataa agttactcga
    21241 gatggtggtc cggctattta tggtcaccag cgagtaggtc ggcatggaaa actttttcca
    21301 tgctacaaat ttcgttctat ggttatgaat tctcaagagg tactaaaaga acttttggct
    21361 aacgatccta ttgccagggc tgaatgggag aaagatttta aactgaaaaa tgatcctcga
    21421 atcacagctg taggtcgatt tatacgtaaa actagccttg atgagttgcc acaacttttt
    21481 aatgtactaa aaggtgatat gagcctggtt ggaccacgac ctatcgtttc ggatgaactg
    21541 gagcgttatt gtgatgatgt tgattattat ttgatggcaa agccgggcat gacaggtcta
    21601 tggcaagtga gtgggcgtaa tgatgttgat tatgacactc gtgtttattt tgattcctgg
    21661 tatgttaaaa actggacgct ttggaatgat attgccattc tgtttaaaac agcgaaagtt
    21721 gttttgcggc gagatggtgc gtattaagct taccgagaag tactgaataa taattgtata
    21781 aattagcctg cgtaaaatct gaacgcatca atcgctacct taatatcata cctttgagtt
    21841 aacatactat tcacctttaa cctgccatga ccgtttgtgg cagggtttcc acacctgaca
    21901 ggagtatgta atgtccaagc aacagatcgg cgtcgtcggt atggcagtga tggggcgcaa
    21961 cctcgcgctc aacatcgaaa gccgtggtta taccgtctcc gttttcaacc gctcccgtga
    22021 aaagaccgaa gaagtgattg ccgagaatcc cggcaaaaag ctggtgcctt attacacggt
//
