LOCUS       EU825758               12932 bp    DNA     linear   BCT 01-JUL-2009
DEFINITION  Salmonella enterica subsp. arizonae rfb gene locus, complete
            sequence.
ACCESSION   EU825758
VERSION     EU825758.1
KEYWORDS    .
SOURCE      Salmonella enterica subsp. arizonae
  ORGANISM  Salmonella enterica subsp. arizonae
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12932)
  AUTHORS   Clark,C.G., Kropinski,A.M., Parolis,H., Grant,C.C.,
            Trout-Yakel,K.M., Franklin,K., Ng,L.K., Paramonov,N.A.,
            Parolis,L.A., Rahn,K. and Tabor,H.
  TITLE     Escherichia coli O123 O antigen genes and polysaccharide structure
            are conserved in some Salmonella enterica serogroups
  JOURNAL   J. Med. Microbiol. 58 (PT 7), 884-894 (2009)
   PUBMED   19502376
REFERENCE   2  (bases 1 to 12932)
  AUTHORS   Clark,C.G., Andrysiak,A., Franklin,K., Gilmour,M., Grant,C.C.,
            Ng,L.-K. and Kropinski,A.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2008) National Microbiology Laboratory, Public
            Health Agency of Canada, 1015 Arlington Street, Winnipeg, Manitoba
            R3E 3R2, Canada
FEATURES             Location/Qualifiers
     source          1..12932
                     /organism="Salmonella enterica subsp. arizonae"
                     /mol_type="genomic DNA"
                     /strain="07-0209"
                     /serotype="41:z4,z23:-"
                     /host="reptile"
                     /sub_species="arizonae"
                     /db_xref="taxon:59203"
                     /collection_date="2007"
     misc_feature    1..12932
                     /note="rfb gene locus"
     gene            34..1197
                     /gene="wbyJ"
     CDS             34..1197
                     /gene="wbyJ"
                     /note="similar to NP_406588.1 putative mannosyltransferase
                     (Yersinia pestis CO92)"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="ACJ26810.1"
                     /translation="MFHSTVMMRNVVENIIFLTLDLVYPDDTGGRKLSLGRILYEQEK
                     GNNVTVIHYNYKKQDEEDAQRFFKENNICFYSFSPRHNHHGFTRLLCYMKSFLNKMPE
                     PYYMIYRDDFFHHFLDAKIEEIAPSLISLESIFLGWTENVIRSKKVKINYTFHNVESE
                     FYYSLFVSEVNKIKKAHYYIQSLLLEVIERRILNDTSANVTYTFLSKEDMSEYMKKYN
                     ISRGNIIINHNNIKTSNKVNRKVDFAEPFFLFPGSLDFPANSFAIKNMLETPNLNWDL
                     LPRIIITGTVSYNTRKKFLGLKNISLVGRVSEDELYRLYSSCIACISPIVTGAGIKIK
                     NLEAIKLGVPLIATKFSCVGINTSNENIFLTENNFNSFYEVMLKYYNEVLNKL"
     gene            1343..2779
                     /gene="manC"
     CDS             1343..2779
                     /gene="manC"
                     /note="similar to AAG41701.1 GDP-mannose pyrophosphorylase
                     (Salmonella enterica subsp. enterica) and to AAG41733.1
                     GDP-mannose pyrophosphorylase (Salmonella enterica subsp.
                     salamae)"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose pyrophosphorylase"
                     /protein_id="ACJ26811.1"
                     /translation="MANTRLCPVVMAGGIGSRLWPLSRELYPKQFLCLQGISTMLQTT
                     INRLDGLECQEPIVICNEQHRFIVAEQLRDINKLAGNIILEPFGRNTAPAIALATIAM
                     KNNSIDHDPLLLILAADHIIQNEEAFRDAVRSAMSYADAGKLVTFGIVPDLPETGYGY
                     IRRGDVVPGATNAVAFEVAQFVEKPGLETAQAYVASGDYYWNSGMFLFRAGRYLEELK
                     KFRPDILAACEQAMRGVDPDLDFIRVDEEAFLACPEESIDYAVMERTADAVMMPMDAG
                     WSDVGSWSSLWEISAHTPEGNVHHGDVISHKTENSYVYAESGLVTTVGVKDLVVVQTK
                     DAVLIADRHAVQDVKKVVEKIKADGRHEHHMHREVYRPWGKYDSIDAGERYQVKRITV
                     KPGEGLSVQMHHHRAEHWVVVAGTARVTINGEVKLLGENESIYIPLGATHCLENPGKI
                     PLDLIEVRSGSYLEEDDVVRFADRYGRV"
     gene            2924..4291
                     /gene="manB"
     CDS             2924..4291
                     /gene="manB"
                     /note="similar to YP_001569856.1 hypothetical protein
                     SARI_00794 (Salmonella enterica subsp. arizonae serovar
                     62:z4,z23:--)"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="ACJ26812.1"
                     /translation="MTKLTCFKAYDIRGRLGEELNEEIAWRIGRACGEFLKPKTIVLG
                     GDVRLTSESLKLALAKGLQDAGVDVLDIGLSGTEEIYFATFHLGVDGGIEVTASHNPM
                     DYNGMKLVREGARPISGDTGLRDVQRLAEANDFPPVNDAARGSYRKITLRDAYIDHLT
                     GYIDLKNLTPLKLVFNAGNGAAGPVIDAIEARLKALGAPVEFIKIHNTPDGTFPNGIP
                     NPLLPECRDDTRNAVIEHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLE
                     KHPGAKIIHDPRLTWNTEDVVTAAGGTPVMSKTGHAFIKERMRHEDAIYGGEMSAHHY
                     FRDFAYCDSGMLPWLLVAELVCLKGQSLGELVADRMAAFPASGEINSRLAEPEEAIAR
                     VERHFADEALAVDRTDGLSMSFPDWRFNLRSSNTEPVVRLNVESRGDNILMESMTYLI
                     KSLLQ"
     gene            4288..5574
                     /gene="wzx"
     CDS             4288..5574
                     /gene="wzx"
                     /note="similar to YP_001569857.1 hypothetical protein
                     SARI_00795 (Salmonella enterica subsp. arizonae serovar
                     62:z4,z23:--)"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="ACJ26813.1"
                     /translation="MNLIINLNKKNMLNRYLQQSSSFFARIGVSLISMVLSVIIVRVY
                     DKSTVSAFFLFVSYTTFLTQVFLLGMTPFLNILAAKKVRSSSIYKEIIKKLYLSIPVT
                     IVVLWGLNETFEIEDIFLLFLATVISGLSSALTELMKGNGSYVASQLYNGGVSTLLFI
                     ILLASNQLLGYDTDIIILYLASLFISSVMNYYQWRLSYNKVHVIDLSLKDKILFKKIL
                     PIYLSTVIVYLFSQVDLWVVSKNFDSSVVAQYGLAIRLAALLSFSTLSVRAIAASRIP
                     ILIQDKKLLQKEIYCSCNFSFVVSLLTLLSLLILGYWLIGMIFGVDYQYSWFILMIFA
                     VGQIVNAATGPCDFLLSHTGHGISLMWITFISFILLIASFVGIQFLEDKTVFLYCSAV
                     SLIIAVQNLSVVYIAFKKTGILALPYFKREYLRVEK"
     gene            5561..6781
                     /gene="wzy"
     CDS             5561..6781
                     /gene="wzy"
                     /note="similar to YP_001569858.1 hypothetical protein
                     SARI_00796 (Salmonella enterica subsp. arizonae serovar
                     62:z4,z23:--)"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="ACJ26814.1"
                     /translation="MSKSNRILIIAFLLLYIISALISMFQTLTQNNYPGELEEFTRSI
                     STVEVILLSMLNIISFILCYFVFLVLSSFRLKLNKNINVIFNKTKINKLFFFLLIAQI
                     FFLVTTGVGKVTTSANEIATSIYSPLFSFLKPEPFIYLFFLYFRMDKNFSYKGNILFT
                     INIVLFIFFKILQGWTSFLLILFFLEMYARYRLKNKKIILLLPLFIIFFGGWVYQYAF
                     VLKNEIRGNDVAPLSYYQGVEQLTSRLSMNPVSLGAYENYDTVVHLYQKENRVFKESG
                     SLLRPILPAGFINKDFRILNNNVMTSFYPDLNPYTSSDFGVVMYYSILFNSSLPGFIL
                     LTILTILLFIIAKIYFDSMSSYNGQYDILLFFIIFYSFYTVSIENVFGQGFFPYIFST
                     LFFFLTGCIKFSRR"
     gene            6855..7949
                     /gene="wbuH"
     CDS             6855..7949
                     /gene="wbuH"
                     /note="similar to YP_001569859.1 hypothetical protein
                     SARI_00797 (Salmonella enterica subsp. arizonae serovar
                     62:z4,z23:--)"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="ACJ26815.1"
                     /translation="MFDEKKEYVIVSATALAASGALTILRQFIEQASINKNSFIIFVP
                     STLALPNYENITYVKTAPKGWLKRIYWDWIGCKKFIKRESLRVKKVICLQNSSMNVPY
                     PQIIYLHQPXPFSNIDFFFKEFNINNFKLLLYKKFYAIFIFKFINKQSIFVVQTEWMK
                     SSLLNRCRNLNVKQVVVLRPDIKLFEARLDNKEISKNTLLYPATALSYKNHLVILKSL
                     TLLKKQFGINDIKFQVTFDKGQYKVFDRYVYENDLSTNIEYLGVISYIELQKKYLSAS
                     LVVFPSYIESYGLPLIEAAILGKRIICSDLPYARDVLNNYEGGIFVKYNDENNWANVI
                     YDVLTNKSCTQIRPYENDNCSSWPRFFDLI"
     gene            7962..8993
                     /gene="fnlA"
     CDS             7962..8993
                     /gene="fnlA"
                     /note="similar to YP_001569860.1 hypothetical protein
                     SARI_00798 (Salmonella enterica subsp. arizonae serovar
                     62:z4,z23:--) and to ABG81792.1 FnlA (Escherichia coli)"
                     /codon_start=1
                     /transl_table=11
                     /product="epimerase/dehydratase"
                     /protein_id="ACJ26816.1"
                     /translation="MFKNSTLLITGGTGSFGNAVLNRFLGTDIKEIRIFSRDEKKQDD
                     MRKKYTSDKLKFYIGDVRDYNSILAATRGVDFIYHAAALKQVPSCEFYPMEAVKTNII
                     GTDNVLEAAIANKVSRIVCLSTDKAVYPINAMGTSKAMMEKVIVAKSRNVPDGMVICA
                     TRYGNVMASRGSVIPLFINQILSGKPITITDPNMTRFMMSLDDAVDLVLHAFTHGSNG
                     DIFVQKSPAATIEILMQAILEIIKLPKHPINIIGTRHGEKLYEVLCSREEMLVAQDQG
                     NYYRIPCDNRDLNYEKYFEKGNKDVEKVEDYNSHNTYRLNKDEMIALLRKLAYINKIE
                     SGDKVDPDA"
     gene            8986..9861
                     /gene="qnlA"
     CDS             8986..9861
                     /gene="qnlA"
                     /note="similar to YP_001569861.1 hypothetical protein
                     SARI_00799 (Salmonella enterica subsp. arizonae serovar
                     62:z4,z23:--) and to ABG81793.1 QnlA (Escherichia coli)
                     and to AAR24275.1 L-QuiNAc synthase (Shigella boydii)"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase (L-QuiNAc
                     synthase)"
                     /protein_id="ACJ26817.1"
                     /translation="MPKKILIIGANGMLGSSLLRFYSKLSEYDVLGTVRNDEAKLKVF
                     KQGFTNIISNVELSNLDIINKIIADFHPDYVFNCVGIIKQLNAAKDYLVSISVNSLLP
                     HQLAQICSRHNVKLIHFSTDCVFSGIHGSYCETDVPDASDLYGKSKQLGEIDYGGHLT
                     LRTSIIGHELSSNHSLIDWFLCQNQTVNGYSKAIFSGLPTVYLAEVIHKYILPNESCI
                     GLRHLSVAPINKYELLGLVKKQYCHDTKIIESTELVIDRSLDSSLFRKETNFVPLCWP
                     ELVEKMNNEYNEYFR"
     gene            9836..10990
                     /gene="qnlB"
     CDS             9836..10990
                     /gene="qnlB"
                     /note="similar to YP_001569862.1 hypothetical protein
                     SARI_00800 (Salmonella enterica subsp. arizonae serovar
                     62:z4,z23:--) and to ABG81794.1 QnlB (Escherichia coli)
                     and to AAR24276.1 L-QuiNAc synthase (Shigella boydii)"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="ACJ26818.1"
                     /translation="MNTMNILDKKLKVVTVVGTRPEIIRLSRVMSVLDQYTDHTIIHT
                     GQNYDYELNEVFFHELKIRKPDYFLNAAGCTAAETIGNVIIEADKIFEKITPEALLIL
                     GDTNSALVAIAAKRRKIPIFHMEAGNRCFDYRVPEEINRKIVDHISDINLTYSEIARE
                     YLLHEGIPADQIIKTGSPMREVLNYYYDDIKKSSALEKLNLVADGYFLVSAHREENVD
                     SPEKLTSLIDILNSISEKYSLPVIVSTHPRTHNRMKNLNVTINNNISFMKPFGFFDYI
                     FLQENAHVVLSDSGTITEESSILNFPALNLRDVHERPEGFEEAAVMFVGLNSERIFQA
                     IEILREQKRGQGERDLYLVSDYSIDNVSLKVLRIIMSYTNFVNHKIWKKA"
     gene            10990..12186
                     /gene="wbwH"
     CDS             10990..12186
                     /gene="wbwH"
                     /note="similar to YP_001569863.1 hypothetical protein
                     SARI_00801 (Salmonella enterica subsp. arizonae serovar
                     62:z4,z23:--) and to ABG81795.1 WbwH (Escherichia coli)"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="ACJ26819.1"
                     /translation="MRIVLICDDYLPDSTRVSAKMMHELACELLRQGHESIVICPNNG
                     TDVKKITHLKLDGVDIFKFPNGKVKDTFKFKRAINESLLSINAWRYLAAEIKNKKIDG
                     VVYYSPSIFFGPLVKRIKSYWHCKSYLILRDSFPQWLIDQGIIRSGGFTDKYFRFFEK
                     INYKSADCIGVMSHKNKELFLKHYPEFSNVCVLYNWTNLKNSTLTRPSEILKQQSLTE
                     KIIFFYGGNIGHAQDMSNLMRLALGMKELDNVHFLFIGQGDEVELVKNFIKIHSLKNC
                     TYLPSISQHEYLSLLRIVHVGLFSLAKNHTVHNFPGKLLGYMANKLPIYGSVNAGNDL
                     KQIVEKAHSGYVHINGDDQSLLDSAVILANDIHIRKKMGENGYALLYERFSVEFAAEH
                     IVLQLQ"
     gene            12210..12707
                     /gene="wbuC"
     CDS             12210..12707
                     /gene="wbuC"
                     /note="similar to YP_001569864.1 hypothetical protein
                     SARI_00802 (Salmonella enterica subsp. arizonae serovar
                     62:z4,z23:--) and to ABG81796.1 WbuC (Escherichia coli)"
                     /codon_start=1
                     /transl_table=11
                     /product="conserved LPS biosynthetic protein"
                     /protein_id="ACJ26820.1"
                     /translation="MQVSLFTAKQMQELIDIAKKSERLRAHLSLHESHQDKVQMVLIA
                     LIKGTYIPPHFHKNIWQWEYFQIINGEVELYIFDENGKVRNIFQLGGKNGALFAKIEP
                     NTIHTLICRSSLAVVLEVKEGPFIELDAKVVPCWAFTESYKTISREKIIYKLENLRVG
                     QVYRI"
BASE COUNT     4010 a   2138 c   2697 g   4086 t
ORIGIN
        1 cgccctttag ctgtaagcca agggcggtag cgtgtgtttc attccactgt gatgatgagg
       61 aatgtagtgg aaaatatcat atttttaaca ttagatcttg tttatccaga tgatacagga
      121 ggtcgtaaat tatcactagg cagaatattg tatgagcaag agaaagggaa taatgtaact
      181 gtaatccatt ataactataa aaaacaggat gaagaggatg ctcaacgttt ttttaaagaa
      241 aacaatatat gcttttattc atttagcccg aggcataacc atcatggttt tactagactc
      301 ttatgttata tgaagtcatt tttaaataag atgcctgaac cctattatat gatatacaga
      361 gatgattttt ttcatcattt tttagatgca aaaattgaag aaatagctcc aagtctaata
      421 tctttagagt cgattttttt aggctggaca gagaatgtaa taaggtcaaa gaaagttaaa
      481 ataaattata cctttcataa tgtagagtct gaattttatt atagtttgtt tgtatctgag
      541 gtgaataaga taaaaaaagc acattattat attcagtccc tattgttaga agttattgaa
      601 cgaagaatat taaatgatac tagtgctaat gttacatata ccttcttatc aaaagaagat
      661 atgagtgaat atatgaaaaa atataacatt agccgtggaa atattataat taatcataat
      721 aacatcaaaa catctaacaa agttaacagg aaagttgatt ttgctgaacc gtttttcctg
      781 tttcctggaa gtttagattt tcctgcaaac agttttgcaa ttaaaaatat gctcgaaacg
      841 ccaaatttaa attgggattt attacccaga attataataa caggaacggt ttcctataat
      901 acacggaaaa aattcttagg cttaaaaaat atttctttgg ttggtagggt ttctgaagat
      961 gaattatata gattatattc atcatgtatt gcgtgcattt cgccaatagt gacaggtgcg
     1021 ggcattaaaa taaaaaactt agaggctata aaattagggg ttcctctaat agccacaaaa
     1081 ttttcctgtg taggtataaa tacctctaat gaaaatattt tccttacaga aaataatttc
     1141 aactcttttt atgaagtaat gcttaaatat tacaatgaag ttttaaataa attataattt
     1201 aaaataaata ttacttaaat tttatagatt gcgattgtta aaaattatct cattcatata
     1261 atgaatagta ggtgtaattc attagtatta aatctttatc gtaaaagata ttatgtttta
     1321 ctggactaaa taaaggtttt aaatggctaa tacgcggttg tgtccagtgg taatggctgg
     1381 aggtatagga agtcgcttat ggcccctatc tagggaactg tatcctaagc aattcctttg
     1441 tctccagggc atatccacta tgttacagac tacaattaat cgattagatg gacttgagtg
     1501 ccaagaacct attgttattt gtaacgaaca gcatcgattt atcgtcgccg aacagctaag
     1561 agatataaat aaattagctg gaaatattat acttgagccc tttggtcgta atactgctcc
     1621 tgcaatagcg cttgcaacaa ttgctatgaa aaataacagt attgaccatg acccattatt
     1681 attaattttg gctgctgacc atatcattca aaatgaagag gccttccgcg acgcggtgcg
     1741 cagcgccatg tcctatgccg acgcgggcaa gctggtgact ttcggtatcg tgccggatct
     1801 gccggaaacc ggctatggct atatccggcg cggcgatgtc gtaccgggcg cgacgaatgc
     1861 ggtggctttt gaggtggcgc agttcgttga gaagccgggg ctggaaaccg cccaggccta
     1921 cgttgccagc ggcgattact actggaacag cggcatgttt ctgttccgcg ccggacgcta
     1981 tctggaagag ctgaaaaagt tccggcccga tatcctggcc gcctgtgaac aggcgatgcg
     2041 cggcgtcgat ccggatcttg acttcatccg cgtggatgaa gaggccttcc tcgcctgtcc
     2101 ggaagagtcc attgactatg ctgtgatgga gcggacggcg gacgcggtga tgatgccgat
     2161 ggacgcgggc tggagcgatg tcggctcctg gtcgtcgctg tgggagatca gcgcccatac
     2221 cccggagggg aacgtccacc acggcgacgt catcagccat aaaaccgaaa acagctacgt
     2281 ttacgccgaa tccggcctcg tgaccaccgt cggcgtgaag gatctggtgg tggtgcagac
     2341 caaagacgcg gtgctgattg ccgatcgcca cgcagtgcag gacgtaaaaa aggtggtgga
     2401 aaaaatcaag gccgacgggc gtcatgagca ccacatgcac cgtgaggttt accgtccgtg
     2461 gggcaaatac gactccatcg acgcgggcga gcgctaccag gtgaagcgta ttaccgtcaa
     2521 gccgggtgaa gggctttcgg tgcagatgca ccatcaccgc gccgagcact gggtggtggt
     2581 ggcaggcacc gccagagtca ccatcaacgg cgaggttaag ctgctcggtg aaaacgagtc
     2641 catctatatt ccgctgggcg caacgcactg cctggaaaat ccgggaaaaa taccgctcga
     2701 tttgattgaa gtgcgttccg gctcgtacct cgaagaggac gatgtggtgc ggttcgcgga
     2761 ccgttacggg cgggtgtagg cctgataaga cgcgaagcgt cgccatcagg caatgagcgc
     2821 tggatagcgc gttttttatc cggcctgcgg atctattggt tatccagaat gaaaattctc
     2881 cttccaggag agggccaact gttgcctgaa gaagggtaag aacatgacaa aattaacctg
     2941 tttcaaagcc tacgatattc gcggcaggct gggcgaagag ctgaacgaag agattgcgtg
     3001 gcggattggc cgcgcctgcg gcgaatttct gaagccgaaa accatcgtgc tgggcggcga
     3061 cgtgcgcctg accagcgaat ccctgaagct ggcgctggcg aaagggttgc aggatgcggg
     3121 cgtcgacgtg ctggatatcg gactgtcggg caccgaagag atttacttcg ccacgttcca
     3181 cctcggcgtg gacggcggta tcgaagtgac cgccagccat aatccgatgg actataacgg
     3241 catgaaactg gtgcgcgagg gtgcccgtcc gataagcggc gacaccggtc tgcgcgacgt
     3301 tcagcgcctg gcggaagcga acgacttccc gccggtcaac gacgccgcgc gcggcagtta
     3361 cagaaaaatc accctgcgcg acgcctacat cgaccatctg acggggtata tcgacctcaa
     3421 aaatcttacg ccgctgaagc tggtatttaa tgccggcaac ggcgcggcgg ggccggtcat
     3481 cgacgccatc gaagcgcggc tgaaggcgct gggcgcgccg gtggagttca tcaaaatcca
     3541 caatacgccg gacggtacct tcccgaacgg cattcccaac ccgctgctgc cggaatgtcg
     3601 ggacgatacc cgtaacgccg ttatcgaaca cggggcggac atgggcatcg cctttgacgg
     3661 cgacttcgac cgctgcttcc tgtttgatga gaaagggcag tttatcgagg ggtactacat
     3721 tgtcggcctg ctggcggaag cgtttctgga aaaacatccg ggggcgaaga ttatccacga
     3781 cccgcggctg acctggaaca ccgaagatgt cgtgacggcg gcaggcggga cgccggtgat
     3841 gtcgaaaacc gggcacgctt ttatcaagga gcggatgcgc catgaagacg ccatctacgg
     3901 cggcgagatg agcgcgcatc actatttccg cgatttcgct tactgcgaca gcgggatgct
     3961 cccgtggctg ctggtggcgg agctggtgtg tctgaagggg cagtcgctgg gcgaactggt
     4021 ggcggaccgg atggcggcgt tcccggcgag cggggaaatc aacagcaggc tggcggagcc
     4081 tgaggaggcc atcgcgcggg tggagcggca ttttgcggat gaggcgctgg cggtggaccg
     4141 cactgacggc ctcagcatgt cattcccgga ctggcgcttc aatctgcgct catcgaacac
     4201 cgaaccggtg gtgcgcctga atgtggaatc acgcggcgat aatatactaa tggagtcgat
     4261 gacttatctt attaagtctt tattacaatg aatttaatta taaatttgaa taagaaaaat
     4321 atgctaaata gatacttgca acaatcaagt tcattttttg caaggatagg tgtttcactg
     4381 atatcaatgg tattaagtgt cataattgtt cgggtatatg ataaaagtac agtaagtgcc
     4441 tttttccttt ttgtaagcta tacaacattt ttgacacaag tttttttgtt gggtatgact
     4501 ccctttctaa atatcttagc agctaagaag gttcgctcct caagtattta taaagaaatt
     4561 attaaaaaat tatatttatc tataccagta acgatagttg tattatgggg attgaatgag
     4621 acatttgaaa tcgaagatat attcctgttg tttttagcta ctgttattag tggattaagc
     4681 agtgcgctaa cagagttaat gaaaggaaac ggttcatatg tagcatctca gttatataat
     4741 ggcggtgtaa gtacattatt atttataatt ttacttgcgt ctaatcaatt gcttggttat
     4801 gacacagata tcataatatt atatttggca tcattattca tttcatcagt tatgaattat
     4861 tatcagtgga ggttaagtta taataaagta cacgtgattg atctttctct gaaagataaa
     4921 attctattta agaaaattct cccaatttat ttatctactg ttatcgtata tttattctcc
     4981 caagttgatc tatgggtggt ttctaagaac tttgactctt ctgtagtcgc tcaatatggg
     5041 ctggcaataa gattggcggc actattgagt ttctcaacat tatcggtgcg cgcaatagct
     5101 gctagtcgta tacccatatt aattcaagat aaaaagctat tacaaaaaga gatttattgt
     5161 agctgtaatt tttcttttgt ggtaagtctc ttaacactgc tatcgttgct tattttaggt
     5221 tattggttaa taggtatgat ttttggtgta gattatcagt attcgtggtt tatattgatg
     5281 atttttgcgg tggggcagat tgtcaacgct gcgacaggac cttgcgattt tctattaagc
     5341 catactggac acggtatatc gctaatgtgg ataactttta tttcattcat actgttaatc
     5401 gcttcatttg tgggaatcca attcttagaa gataaaacgg tttttttata ttgcagtgct
     5461 gtgtctctca ttattgctgt gcagaattta agcgtggtat atatagcctt taaaaaaaca
     5521 ggtattttgg cgctaccata ttttaaaaga gaatatttac gtgtcgaaaa gtaatagaat
     5581 tttaatcatt gcatttttgt tgttatatat tatatctgcg ttaatatcaa tgtttcagac
     5641 tttaacgcaa aataactatc caggcgaatt agaagagttc acaaggtcta tctctactgt
     5701 tgaagttatc ctgttgagca tgttaaacat tatctcattc atactttgct attttgtgtt
     5761 tctcgtgctt tctagtttta ggcttaagct taataaaaat atcaacgtga tttttaataa
     5821 gacaaaaatt aataaattat tctttttctt attaattgca caaatatttt ttttagtaac
     5881 aacgggagta ggaaaagtaa ctactagtgc taatgaaatt gcaacttcca tttacagtcc
     5941 tttattttct tttctgaaac ctgagccgtt tatatattta ttttttctgt attttagaat
     6001 ggataagaat ttctcttata aaggtaatat tctgtttaca ataaacattg tattatttat
     6061 tttctttaaa atacttcaag gatggacaag ttttcttctt atactgtttt ttttagagat
     6121 gtacgcgcga taccgcctaa aaaataaaaa aattatttta ttgctacccc tgtttattat
     6181 tttttttggt ggctgggtat atcagtatgc ctttgtatta aaaaatgaaa ttcgtgggaa
     6241 tgatgtggct cctttgagtt attaccaagg ggttgaacag ttaacatcta ggctatcaat
     6301 gaatcctgtt tcattaggtg cttatgaaaa ttacgatact gtagtacatc tatatcaaaa
     6361 agaaaataga gtttttaaag aatctggatc tttattgagg ccaatactac ctgcaggttt
     6421 tataaataaa gattttagaa tactcaataa taatgttatg acatcatttt atccagactt
     6481 aaatccatat acgagctctg attttggtgt tgtaatgtat tacagcatat tgtttaattc
     6541 tagcctacct ggttttatac tgttaactat acttactatc ctgttgttta ttatagcaaa
     6601 aatatatttt gattctatgt cgtcttataa tgggcaatat gatatcttac ttttttttat
     6661 tattttttat tcattttata cagtaagtat agaaaacgta tttggacaag ggttctttcc
     6721 atacatattt agtactttat tttttttctt aactggttgt atcaaattta gccgaaggta
     6781 actattacga ttgctagtat ttcaaaagat taataatttt acagtatgta taacaataaa
     6841 atagtaggta tttaatgttc gatgaaaaaa aagagtatgt tatcgttagt gcaactgcat
     6901 tagcagcaag cggggcatta actatcttac gacaatttat tgagcaagca tcaattaata
     6961 aaaatagctt tattatattc gtaccatcca ccttggcttt acctaattat gaaaatatta
     7021 cttatgttaa gactgctcct aaaggttggc tgaaaagaat ttattgggat tggataggat
     7081 gcaaaaaatt tataaaaaga gagtcgctta gggttaaaaa agttatttgt ctacaaaact
     7141 caagtatgaa tgtaccttat ccgcagatta tttaccttca tcagcctwtt ccctttagta
     7201 atattgattt cttcttcaaa gaatttaata taaataattt taaattattg ctatacaaaa
     7261 aattttatgc aatatttatt tttaagttta taaataaaca atctattttt gtcgtacaaa
     7321 cagagtggat gaaaagtagc cttttaaatc gatgccgaaa tttaaatgta aagcaagttg
     7381 ttgttttaag gccagatatt aagttgtttg aagcgagact tgataacaag gaaatatcaa
     7441 aaaatacatt attgtatcca gctacagcat taagctataa aaatcattta gtcatcctta
     7501 aaagcttaac tttgctaaaa aaacaatttg gcataaatga tattaaattt caggttactt
     7561 ttgataaagg gcaatataaa gtatttgatc gttatgttta tgaaaatgat ttgtctacta
     7621 atatagaata cctaggggtg atatcttata tcgaattgca aaaaaaatac ctcagcgcat
     7681 cactggttgt atttcctagc tatatagaat catatggatt accgttaata gaagccgcca
     7741 tcttaggtaa acggattata tgtagtgatt tgccatatgc aagggatgta cttaataatt
     7801 atgaaggagg gatttttgtc aaatacaatg atgaaaataa ttgggctaat gtcatctatg
     7861 atgtactaac aaacaagtct tgcacacaaa tcaggcctta tgagaatgat aattgttctt
     7921 cctggccacg tttttttgat cttatttaat aaaggtaaaa aatgtttaag aattctacat
     7981 tactaataac tggcggaacg ggttctttcg gtaatgctgt tttaaatcgt tttttgggaa
     8041 ccgatatcaa ggaaattcgc attttttcac gagatgaaaa aaaacaagat gacatgagga
     8101 aaaaatacac cagtgataag cttaaatttt acattggaga tgttcgtgat tataacagca
     8161 tattagcagc aacaagagga gttgatttta tctatcatgc agcagcattg aaacaagtac
     8221 catcatgcga gttttacccg atggaggctg ttaaaacaaa tataattggg acggataatg
     8281 ttttagaggc agccattgct aataaggttt cacgtatagt ttgcttaagt actgataagg
     8341 ctgtttaccc cattaatgct atgggcacat caaaagcaat gatggagaaa gttattgtag
     8401 ctaaatccag aaatgttcct gatggaatgg ttatatgtgc tacgcgttat ggaaatgtca
     8461 tggcctcacg tggttcagta ataccgcttt ttataaatca aattttaagc ggcaaaccaa
     8521 ttaccattac tgaccccaat atgacgcgtt ttatgatgag tttagatgat gctgttgatc
     8581 ttgttctgca tgcttttact catggtagca atggagatat ttttgttcaa aaatcaccgg
     8641 cagcaacgat tgaaatctta atgcaagcaa tccttgagat tattaaatta cctaagcatc
     8701 caataaatat tattggtaca agacatgggg aaaaactgta tgaagtgctc tgtagtcgtg
     8761 aggagatgtt agtcgcccag gaccaaggta attattaccg aattccttgt gataatcgtg
     8821 atcttaatta tgaaaaatat tttgagaaag gtaacaagga tgtagaaaag gttgaggatt
     8881 ataactctca taatacatat cgtttaaata aagatgagat gattgcatta ttacgtaaac
     8941 ttgcttacat caataaaatt gaatccggtg ataaggttga tccagatgcc taagaaaatt
     9001 ctaattattg gtgctaatgg aatgttggga agttctttat tgcgctttta ttcgaaactt
     9061 tctgaatatg atgttttagg cacggtaaga aatgatgagg caaagttaaa agtttttaaa
     9121 caaggattta ctaatataat tagtaatgtt gaattgtcta atttagatat aattaataaa
     9181 attatagctg actttcatcc agattatgtt tttaattgtg tagggattat aaagcagctt
     9241 aatgctgcta aggattattt ggtatcaatc tctgttaact cgctattacc tcatcaattg
     9301 gcacaaattt gttctaggca taatgtgaaa ctaattcatt tttcgactga ttgtgtgttc
     9361 agtggaatac acggttccta ttgtgaaact gatgttcctg atgcttctga tttatatgga
     9421 aaaagtaaac aacttggtga aattgattat ggcggtcatt tgacattgcg tacttctatt
     9481 ataggacatg aactttcaag taatcatagt ttaattgatt ggtttttgtg tcagaatcaa
     9541 acggttaacg gatattcaaa agcaatcttt tctggattgc ccactgtgta tctagccgag
     9601 gttattcata aatatatact acctaatgaa agttgtatag ggttgagaca cttaagtgtt
     9661 gcgccgatta ataaatatga gttgctaggt ttagtcaaaa aacaatattg ccacgacact
     9721 aagattatag aatctactga acttgttatt gatcgcagtc ttgattcatc tttatttcgt
     9781 aaagaaacga actttgtacc tctgtgttgg ccagaactag ttgagaaaat gaataatgaa
     9841 tacaatgaat attttagata aaaaactaaa agtagttact gtagtcggaa ctcgaccaga
     9901 gattattaga ttatcgcggg tgatgtctgt attagaccaa tatacagatc atacgattat
     9961 tcatacagga caaaattatg actatgaatt aaatgaggta ttttttcatg agcttaagat
    10021 tagaaaaccg gattatttcc ttaacgcagc aggttgtact gcagctgaaa caattggtaa
    10081 tgtaatcatt gaggctgata agatctttga aaagattact ccagaagctc ttctgattct
    10141 aggcgataca aatagtgctc ttgttgctat tgcagctaaa cgtcgaaaaa ttccaatttt
    10201 ccatatggag gcggggaatc gatgctttga ctatcgagtt ccagaagaaa ttaataggaa
    10261 aattgtagac catatttctg atattaatct tacttacagt gaaatagcgc gtgaatattt
    10321 attacatgaa ggtattcccg cagatcagat tataaaaacc ggtagtccta tgcgagaggt
    10381 attaaattat tattatgatg atattaaaaa atcatctgca ctcgaaaaac taaatttagt
    10441 agctgatgga tattttctgg taagtgctca tagagaagaa aatgttgatt ctccagaaaa
    10501 attaactagt ctgatagaca tattaaattc aatatctgaa aaatattctt taccagttat
    10561 tgtttcgaca catcctagaa ctcataatag aatgaaaaat cttaatgtca ctatcaataa
    10621 taatataagt tttatgaaac cttttggttt ttttgattat atttttttac aggaaaatgc
    10681 tcatgtagtg ctttctgata gcggtaccat tactgaagaa tcttctattt taaattttcc
    10741 tgcgcttaat cttagagatg ttcatgaaag acctgaagga tttgaagaag ctgctgtaat
    10801 gtttgtagga ttgaatagcg agcgtatatt tcaggcaatt gagatccttc gtgaacaaaa
    10861 acgtggacaa ggtgagcgtg atttatattt ggtttctgat tattcaattg ataatgtctc
    10921 acttaaggtt ctacgaatta ttatgagtta tacaaatttt gttaatcata aaatttggaa
    10981 gaaggcataa tgcggatagt gttaatttgc gatgactatc tgcctgatag tacacgcgta
    11041 agtgccaaaa tgatgcatga gctcgcttgc gaacttctca gacaaggaca tgaatcaata
    11101 gttatatgtc caaataatgg gacagacgta aaaaaaatca ctcatctgaa acttgatggt
    11161 gttgatattt ttaagtttcc caatggaaaa gttaaagata catttaagtt taagcgtgcg
    11221 attaacgaaa gcttgctttc cataaatgca tggcgttact tggcagctga aattaaaaac
    11281 aaaaaaattg atggggtggt ttattattcg ccttcaattt tttttggccc gctagttaag
    11341 agaataaaaa gctattggca ttgtaaatcg tacttgattt taagggattc atttccacaa
    11401 tggcttattg atcagggaat aatccgtagt ggtgggttta cggataaata tttcaggttc
    11461 tttgagaaaa taaattataa atctgctgat tgcattggag taatgtctca caaaaataaa
    11521 gagttgtttt tgaaacacta ccctgagttt tctaatgttt gcgtgctata caattggact
    11581 aatctgaaaa acagcacttt aactcgccca agtgaaatac tcaagcagca gtcattaaca
    11641 gaaaaaatta tattttttta tggcggtaat attggtcatg cccaagatat gagtaattta
    11701 atgcgacttg cattgggaat gaaggagctt gataatgttc attttctttt tatagggcaa
    11761 ggtgatgaag ttgaattggt taagaatttt attaaaatac actcgctaaa aaattgtacg
    11821 tatttaccat caatcagcca gcatgaatat ttatccttat tgaggatcgt tcatgtcggg
    11881 ttatttagtt tggcaaaaaa tcatactgta cataactttc caggaaaact tcttggatat
    11941 atggccaata agttgccaat ttatggtagc gtaaatgctg gaaatgactt aaagcaaatt
    12001 gttgaaaaag ctcactcagg ctatgtacat attaatgggg atgaccagag tttattagat
    12061 tcggcagtta tattagctaa tgatatacac atccgaaaaa aaatggggga aaatggttat
    12121 gctcttttat acgaacgatt ttctgtagag tttgcagctg aacatattgt attacagcta
    12181 cagtaatttt tataaatgta ggtcttccta tgcaagttag tttgtttaca gcaaaacaaa
    12241 tgcaagaatt gattgacatt gcaaaaaaat ctgaacgact gagagcgcat ttaagcttac
    12301 atgaaagtca tcaagataaa gttcaaatgg ttctgattgc cttaatcaaa ggtacatata
    12361 tccctccgca ctttcataaa aacatatggc aatgggagta ttttcagatc attaatggtg
    12421 aagtggagtt atatatattt gatgaaaatg gtaaagtgag aaatatattt caattaggcg
    12481 gtaagaatgg tgcattattc gctaaaatag aacctaatac tattcataca cttatctgtc
    12541 gttcatcact tgctgttgta ttagaggtta aagaagggcc atttatcgag ttagatgcaa
    12601 aagtagtacc ttgctgggca tttactgaaa gttataaaac catctctcga gaaaaaatta
    12661 tttacaaatt agagaattta agagtcggtc aggtgtatcg aatttaatag tctacaatat
    12721 agcctattga aagcatgatt tgtatgatat aaattatcat ctatatatca tttcatttaa
    12781 aataggcaca tgcatgaact atcatgcaga tgaatattga gttaatattt ttgatacgtt
    12841 aaaatcgcgc gccttcgtcg cgcggtgacc acacctgaca ggagtatgta atgtccaagc
    12901 aatagatcgg cgtcgtcggt atggcagtga ag
//
