LOCUS       JX975340               11146 bp    DNA     linear   BCT 27-AUG-2013
DEFINITION  Salmonella enterica strain G1461 O antigen gene cluster, complete
            sequence.
ACCESSION   JX975340
VERSION     JX975340.1
KEYWORDS    .
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11146)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Senchenkova,S.N.,
            Reeves,P.R. and Wang,L.
  TITLE     Structural diversity in Salmonella O antigens and its genetic basis
  JOURNAL   FEMS Microbiol. Rev. (2013) In press
   PUBMED   23848592
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 11146)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Reeves,P.R. and
            Wang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-OCT-2012) TEDA School of Biological Sciences and
            Biotechnology, Nankai University, 23 Hongda Street, TEDA, Tianjin
            300457, P.R. China
COMMENT     ##Assembly-Data-START##
            Sequencing Technology :: Sanger dideoxy sequencing
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..11146
                     /organism="Salmonella enterica"
                     /mol_type="genomic DNA"
                     /strain="G1461"
                     /db_xref="taxon:28901"
                     /note="serogroup: O42"
     misc_feature    1..11146
                     /note="O antigen gene cluster"
     gene            106..1191
                     /gene="rmlB"
     CDS             106..1191
                     /gene="rmlB"
                     /note="RmlB"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase"
                     /protein_id="AFW04805.1"
                     /translation="MKILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLC
                     DISKSNRYNFEHADICDSAEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEVARKYWSALGEDKKNSFRFHHISTDEVYGDLPHPDEVGNSVTLPLFTETTA
                     YAPSSPYSASKASSDHLVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KSLPIYGKGDQIRDWLYVEDHARALYIVVTEGKAGETYNIGGHNEKKNLDVVFTICDL
                     LDEIVPKATSYREQITYVADRPGHDRRYAIDADKISRELGWKPLETFESGIRKTVEWY
                     LANTKWVNNVKSGAYQSWIEQNYEGRQ"
     gene            1191..2090
                     /gene="rmlD"
     CDS             1191..2090
                     /gene="rmlD"
                     /note="RmlD"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-L-mannose-dehydrogenase"
                     /protein_id="AFW04806.1"
                     /translation="MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEFCGDFSNPK
                     GVAETVRKLRPDVIVNAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWEVHY
                     STDYVFPGTGDIPWQETDITSPLNVYGKTKLAGEKALQDSCPKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKERQTLSVINDQYGAPTGAELLADCTAHAIRVALKKPEVAGLYHLVAG
                     GTTTWHDYAALVFDEARKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFG
                     LILPQWELGVKRMLTEMFTTTTI"
     gene            2138..3016
                     /gene="rmlA"
     CDS             2138..3016
                     /gene="rmlA"
                     /note="RmlA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="AFW04807.1"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGN
                     DDCALVLGDNIFYGHDLPKLMDAAVNKEDGATVFAYHVNDPERYGVVEFDQNGTAVSL
                     EEKPLQPKSNYAVTGLYFYDNSVVAMAKKLKPSARGELEITDINRIYMEQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDAEQIKNLAKPL
                     SKNAYGQYLLNMIKGY"
     gene            3021..3554
                     /gene="rmlC"
     CDS             3021..3554
                     /gene="rmlC"
                     /note="RmlC"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-D-glucose-3,5-epimerase"
                     /protein_id="AFW04808.1"
                     /translation="MNVIKTEIPDVLIFEPKVFSDERGFFMESFNQTVFEEAVGRKIE
                     FVQDNHSKSTKGVLRGLHYQVEPYAQGKLVRCIAGEVFDVAVDIRKDSETFGKWIGVN
                     LSSENKRQLWIPEGFAHGFLVLSEEAEFLYKTTNFYNPRSDRGVAWNDPYIGINWPLI
                     NNPLLSDKDSKQPFLFR"
     gene            3578..4837
                     /gene="wzx"
     CDS             3578..4837
                     /gene="wzx"
                     /note="Wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AFW04809.1"
                     /translation="MLINKEYKNVIYNAGYLLCTQGVAYIAPIIVLGHLIATLGIDGF
                     GKYAFALVLMAYFQVIIDYGFAFSSSRAISQSRDDVCQISRIYFATSFIKIILALILF
                     VVIYVICTVLVNDNTYIILTLSAFLWAFSNSIYPLWFFQGIERLKIVAIINIISRSLA
                     CIFVLYFVRKESDINFAILAQALPVLLGAIYANTVIFIKKYIRLRLPSAKFIFFSLRD
                     GWDYFLATLASTLLTNSAVFILGMYYTPSVVGVYAIVERIVKAIVSLFSPLTQSLYPY
                     NCRKFKESFDIGILTALHTGRLLVILSLIISVIFLISWEVIYPRMNFPQETLIYAFLL
                     VPWLCLGVLNNVLGIQILSASGYAKMYSRSFIYSAIFTVIFLLLLIGLFEGYGAAIAV
                     SGGEFLLCILLLNNIRKVKDKRFNKEF"
     gene            4839..5972
                     /gene="mnaA"
     CDS             4839..5972
                     /gene="mnaA"
                     /note="MnaA"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="AFW04810.1"
                     /translation="MKKIFLIFGTRPEAIKMAPLVEKLKNDNRFCCKVCVTGQHREML
                     DQVLKLFQIEPDYDLNVMKPGQTLVSLTSIILLKLNEIFSRDKPDIILVHGDTTTTLA
                     ASLAAYYNQVIVGHVEAGLRTGDLYSPWPEEGNRKLTASIANLHFAPTATSESNLIRE
                     NIAKENIHIVGNTVIDALLTIVNKIRNQSELQTKIVESLPFKTDEAKIILITGHRREN
                     FGNGFENICVAIRNVALKFKDHIFVYPVHLNPLVQKTVRDILTGIENIYLIEPLEYLQ
                     FVYLMDKAYVIVTDSGGIQEEAPSLGKPVLVTRDTTERPEAVDAGTVRLVGTNKVKIF
                     DELSLLLTDKSEYEKMSNASNPYGNGQTSERIVNVLAEWFSLK"
     gene            6043..7128
                     /gene="wekM"
     CDS             6043..7128
                     /gene="wekM"
                     /note="WekM"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04811.1"
                     /translation="MILFIADFPTVENVRDGMFQRIAAIDSLTKNKSRVYLNISFKKN
                     VKRKVSIIENCVVEHVNYFAHNKIIKNYLKKASIIYVHSLYNMLKISSANCYDKIILD
                     IHGVVPEEIAFLGKKTKSFIYNKIEKKAIRSCYKLIHVTTAMKEFYERKYNLNLASRS
                     IVLPIFEKTTINPNHSKWESNTFETIYAGGMQAWQNIDLMIKVTKGGDTRNIKFNFFF
                     PQELISDFKLKLGDRLDSRTIMVDSLPKEDVIKVMTRCHLGFVLRDDIVVNRVACPTK
                     LIEYLECGVVPIIKSPDIGDFNTLGYSFIRVEELNGSLSMDDLRKKVENNYKVLAHFQ
                     SLTEHSKSILINIFKNANERLENKVMP"
     gene            7699..8715
                     /gene="wzy"
     CDS             7699..8715
                     /gene="wzy"
                     /note="Wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AFW04812.1"
                     /translation="MPVKTNNFLYFIMVISATIFAVKIVPYSNDYQAYIDLFKYTIQD
                     PSYERMEIGFKNLIGFSKFLDLNFDVLWFLVAFISLSLKCYVLKSYDSDILVLFLLYF
                     LYAISLLALHETTQIRAAIAIALGIAGFRCTNKFVGICLILSSVLFHYSAILFIILYT
                     LSFIVKPYKFTWLIVVVTMAILIPLLLEQYSDPLISINPLFSLYLENSDNAKVNKFSF
                     TLILATIFFVINFFIGRKINYYSNNNFIFKQYNLFSFLYLSSVVLLSALSFSPVISIR
                     LYELFSLSPFIIIACLYSKSMKYVFYSNINLRLLRRVLLLTLWLISVHRFIAYYFVNP
                     IIKF"
     gene            8721..9659
                     /gene="wekN"
     CDS             8721..9659
                     /gene="wekN"
                     /note="WekN"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04813.1"
                     /translation="MIKRNYNVSSNNVPYIAAVLVTFNPDLNIFQEVINTISSQVQHL
                     IVIDNCSKNRLDISLFLNGKEGVVLLPQNNNIGLAATQNIGIQYVKENINATHVILFD
                     QDSIIKPYFISNLVNEELGLISKGIKVGAIGPSFYDPDNNQDYPATVYIGPFIKRVKL
                     GDNPVEATFLIASGCLINLNVLKNVGGMLEELFIDYIDVEWSLRAKKFGYRLFITPKA
                     SMAHTIGDKRISLFGRTVSCHSSFRRYFLVRNSFKMLRLPYIPIGYKVRETVFNFLRV
                     IIGLATSSDRKKFIKYTLAAFKDGFFGKFGPCKYNF"
     gene            9661..10827
                     /gene="wdaW"
     CDS             9661..10827
                     /gene="wdaW"
                     /note="WdaW"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04814.1"
                     /translation="MIKIAHIQLLPLLSGVQRVCLDELIRLDENKFDKYLICKEEGPL
                     TVEAKKYGIKCLMVRNLVREISLKNDLKALWSLWKIIKQYKFDIVHTHSSKTGVLGRV
                     AAWLNRTNLIVHTVHGFSFPIAKNKQQRILFWLMEKIGSMCGDIIICLHEDDAKIAQS
                     ILKINKHKICIISNGVDIEKFKPYDEGRKFLCRENIKGIDSDDIIIGMIGRLWPQKNP
                     ICLLRAVAEIIKSNKKVKCFFIGDGELYGEMAHFIKSNHLSNNVQLFGWRNDTHTFLN
                     AMDIFVLPSLWEGMPLAILEAKSCGLPCVVSNIQGNRSIIDGVEDGLLFDLDLSWHDL
                     YEKLQLLIGDSQLRSIIGKKARLSIINHYNIASRIKKIERMYLRKIKKHSHVNS"
BASE COUNT     3519 a   1718 c   2228 g   3681 t
ORIGIN
        1 attggtagct gtaagccaag ggcggtagcg tgtgtaacga cttgactact taatttttat
       61 tggcaaatta aataccacat taaatacgcc ttatggaata gaaaagtgaa gatacttatt
      121 actggcgggg caggttttat tggatcagct gttgttcgcc atattattaa gaatacacag
      181 gacactgtag ttaatattga taaattaacc tacgccggta atcttgaatc cctttgtgat
      241 atttctaaaa gtaatcgcta taattttgaa cacgcggata tttgtgattc cgctgaaata
      301 acgcgtattt ttgagcaata ccagccggac gcggtgatgc atttggctgc ggaaagtcat
      361 gtggaccgtt cgattaccgg gccggcagct tttattgaaa ccaatatcgt cggtacttat
      421 gttcttcttg aagttgcgcg taaatattgg tctgcgcttg gtgaagataa aaaaaatagt
      481 ttccgctttc atcatatttc aactgatgaa gtttacggcg atttaccaca tcctgatgaa
      541 gttgggaata gcgttacgct gccgttattt actgaaacga cggcatatgc gccaagtagc
      601 ccctactctg cgtcaaaagc atccagcgat catttagttc gtgcctggag gcgtacttat
      661 ggtctgccaa cgatcgttac caattgttct aataactatg gtccttacca tttccccgaa
      721 aaactgattc cgttggtcat tttgaatgca ctggaaggaa agtctttgcc aatttatggt
      781 aaaggggatc agattcgcga ctggctatat gtagaagatc acgctcgagc gctttatatt
      841 gtagtgactg aaggtaaggc aggagagact tataacattg gtggacacaa tgagaagaaa
      901 aatctcgatg tagtatttac catctgtgat cttctggatg agattgtacc caaagcgact
      961 tcttatcgtg aacaaatcac ttatgtcgcg gatcgtccag gtcatgatcg tcgttatgcc
     1021 attgatgcag ataaaattag tcgcgaatta ggctggaaac cgctggagac ctttgaaagc
     1081 ggtattcgta aaacagtgga atggtatctc gctaatacaa aatgggtaaa caatgttaaa
     1141 agtggggcgt atcagagttg gattgaacag aactatgaag gacgccagta atgaatatct
     1201 tactttttgg taagacaggg caagtaggct gggagttgca acgttctctg gcgcctgtgg
     1261 ggaatctgat tgccctggat gtccattcaa aagagttttg cggtgatttt agcaatccga
     1321 aaggcgttgc cgaaactgtt cgtaagcttc gtcccgatgt gattgttaac gcagcagcac
     1381 atactgcagt agacaaagca gagtctgaac cagaactagc gcagttactt aacgccacca
     1441 gtgtggaagc catcgctaaa gcggctaacg aaactggcgc atgggaagtg cattattcaa
     1501 ctgattatgt attccctggt accggcgata tcccatggca ggaaacggac atcacgtcgc
     1561 cgctaaatgt ctatggcaag accaaactag cgggagaaaa ggccctgcag gatagctgcc
     1621 caaagcacct tatcttccgc accagttggg tttatgcagg taagggcaat aatttcgcaa
     1681 agacaatgct tcgtctggcg aaagagcgtc agacactttc ggtcatcaac gatcagtacg
     1741 gtgcgccaac cggtgcggaa ttactggctg actgcacggc tcatgcgatc cgtgtggcgt
     1801 taaagaaacc agaagtagca ggtctttacc atctggtggc cggtggaacc acaacctggc
     1861 atgactacgc tgcgttagtc tttgacgagg cgcgcaaggc agggataacg cttgcgctta
     1921 ctgagcttaa tgccgtgcca accagtgcct atccgacgcc ggcgagcaga cctggaaatt
     1981 cgcgtctcaa tactgaaaag tttcagcgta attttggcct tattcttccc cagtgggaat
     2041 taggggttaa gcgtatgctg actgaaatgt ttacgacgac aaccatctga taaatttaaa
     2101 tgcccataag ggcattttct gtgaatgaga aatggaaatg aaaacgcgta agggcattat
     2161 tttagcgggg ggctccggca ctcgtcttta tcctgtgacc atggcggtaa gtaagcaatt
     2221 gctgccaatc tatgataaac cgatgattta ctatcccctt tccacgctta tgctggcagg
     2281 cattcgggat atcttgatca tcagtacgcc acaggacacg ccgcgttttc aacaactgct
     2341 gggagacggt agccagtggg ggctgaatct tcaatataaa gtacaaccaa gcccggatgg
     2401 cttagcacag gcgtttatta ttggtgaaga gttcattggt aacgatgact gtgcattagt
     2461 gctgggtgac aatatcttct atggtcacga tttgcctaaa ctaatggacg ctgccgttaa
     2521 taaagaagat ggcgctaccg tctttgctta tcatgtaaac gatccggagc gctacggtgt
     2581 ggttgagttt gaccaaaatg gcacagccgt tagtctggaa gaaaaaccgt tacaaccgaa
     2641 gagtaattat gcggtaacgg gtctttattt ttatgataat agcgtggtgg cgatggcgaa
     2701 aaaacttaag ccttccgctc gcggtgagtt agagatcacg gatattaacc gtatttatat
     2761 ggagcaggga cgcttgtcag ttgcgatgat ggggcgcggc tatgcctggc tggatacggg
     2821 tacacatcag agtttgatag aggccagtaa ttttattgca accatcgaag aacgccaggg
     2881 gctgaaagtg tcttgtccgg aagagatcgc ttatagaaaa gggtttattg atgcggagca
     2941 gattaaaaat ctggctaaac cgttgtccaa gaatgcttat gggcagtatc tcctgaacat
     3001 gattaaaggt tattaataaa atgaacgtta ttaaaacaga aattcctgat gtattaattt
     3061 ttgaacctaa agtgtttagt gatgaacgtg ggttctttat ggaaagtttt aatcagacag
     3121 tatttgagga agcggttggt cgaaagattg aatttgttca ggataatcat tcaaaatcaa
     3181 ctaaaggtgt attacgtggt ttacattatc aagttgaacc ttatgctcaa gggaagcttg
     3241 tacgctgtat agcaggagaa gtttttgatg ttgctgtaga tattcgcaaa gattctgaaa
     3301 cgtttggtaa atggattggt gtcaatcttt cttctgaaaa caaaaggcag ttgtggatac
     3361 ctgaaggttt tgctcatggg ttcttagtat taagtgaaga agctgagttt ttatataaaa
     3421 caacaaattt ttataaccct aggagtgacc gaggggtggc ttggaatgat ccttatatag
     3481 gaattaattg gccattaata aataatccat tattgtctga taaggattct aagcaaccat
     3541 tcttgttcag atgaatatag ttgtgtaaga ggcttttatg ttgataaata aagaatataa
     3601 aaatgtaata tataatgctg gctatttact atgcacacaa ggtgtcgcgt atatagcacc
     3661 aatcattgta ttaggacatc ttatagcaac gcttggcatt gatggttttg gcaaatatgc
     3721 gtttgcattg gtattgatgg catattttca agtaatcatt gattacggat ttgccttcag
     3781 ttctagtcga gctatatcgc aaagtagaga tgatgtatgt caaatatcaa gaatatattt
     3841 tgctactagc tttattaaaa ttattcttgc attaatatta tttgttgtaa tttatgtgat
     3901 ttgtactgta ttggttaatg acaacactta tatcatactt acattgagtg catttttatg
     3961 ggcattttct aattcaatat atccattatg gttctttcag gggattgaga gactaaagat
     4021 agttgcaatt attaatatta tatcacggtc gcttgcatgc atttttgtat tatattttgt
     4081 tcgtaaggaa agtgatatta attttgctat tttagctcag gcgctacctg tacttctagg
     4141 tgcaatatat gccaacacag ttatttttat aaaaaaatat ataaggctaa gattgccttc
     4201 agctaaattt atttttttct ctctaagaga tggttgggac tattttttag caacacttgc
     4261 ttctacatta ttaactaata gtgccgtttt tattctagga atgtattata cgccatcagt
     4321 agtaggcgtt tatgctattg tagaacgaat agtgaaggct attgtttcgt tgttttctcc
     4381 attaacacag tcactttacc catataattg taggaagttt aaggaatctt ttgatattgg
     4441 catattgaca gctctccata cagggcgctt attagtaata ttgagcctta ttattagtgt
     4501 gatctttctt atttcatggg aagtaatata tccgagaatg aattttccac aggaaacgtt
     4561 gatttatgct ttcttacttg taccatggct ttgtttgggt gttctaaata atgttcttgg
     4621 tattcaaatc ttaagtgcat ctggttatgc caaaatgtat agccgtagtt ttatttattc
     4681 tgctatattt actgtgattt ttcttttatt acttattggc ctctttgaag gctatggtgc
     4741 tgccatagca gtttcagggg gagagtttct cttatgtata ctactgctca ataatataag
     4801 aaaagtcaag gataaacgtt ttaataaaga attttgatat gaaaaaaata tttttaattt
     4861 ttggtactcg tccggaagcc ataaaaatgg cacctttagt tgaaaaatta aagaatgata
     4921 acagattttg ctgtaaggtt tgtgtcacag gtcagcatag agaaatgtta gatcaggtgt
     4981 taaagctgtt ccaaatagaa cctgactatg atttaaatgt gatgaagcca ggtcaaactc
     5041 ttgtgtctct cacgagtata attttattaa agttgaatga gatcttttca agagataaac
     5101 ctgatataat tcttgtgcat ggtgatacta cgactacttt agctgcatcc cttgctgcat
     5161 attataacca agttatagtg ggacatgttg aagctggtct acgaacagga gatttatact
     5221 ctccatggcc ggaagagggc aatcgtaaac ttactgcaag tattgccaat ttgcactttg
     5281 caccgacggc gacttcggaa tctaatctga taagagaaaa tatagctaaa gaaaatattc
     5341 acatagtcgg taatacagtt attgatgcgc tgctaacgat agttaataaa atccggaatc
     5401 aatcggagct acaaaccaaa atagttgaaa gcctaccatt caaaaccgat gaggctaaaa
     5461 ttatattaat aacagggcat cgtagagaaa attttggaaa tggtttcgaa aatatatgtg
     5521 ttgcaatacg taatgtagcg ctaaaattca aagatcatat atttgtatac ccggtacatc
     5581 ttaatccatt ggttcaaaaa acagtcagag atatcttaac tggtatagaa aatatatact
     5641 taattgagcc tttagagtat ttgcaatttg tttatttgat ggataaagca tatgtcattg
     5701 taactgactc cgggggaata caagaagagg ccccttcttt aggaaaacca gtccttgtta
     5761 caagagatac aactgaacga ccagaagcag ttgatgcagg tactgttaga ttagtaggca
     5821 ctaataaagt gaaaatattt gatgaattaa gtttattact tactgataaa agtgaatatg
     5881 aaaaaatgtc aaatgcttct aatccatatg gtaatggaca aacatctgag cgaattgtaa
     5941 atgtattagc tgaatggttt agtctaaaat aattaaacct agttaacgat aatacattag
     6001 caaatttaga taaattcatt aaaatataaa taatggtgtt atatgatttt gtttatagca
     6061 gatttcccta cggttgagaa tgttcgtgat ggcatgtttc aacggattgc cgcgattgat
     6121 tcattgacta aaaataagag cagggtttat ttaaatatat cattcaagaa aaatgtaaag
     6181 aggaaagtat ctattataga aaattgtgta gttgaacatg taaactattt tgcacataat
     6241 aaaataataa aaaattactt aaaaaaagca tcaattattt atgttcactc attatataat
     6301 atgttgaaaa tctcatccgc taattgttat gataaaatca ttcttgatat tcatggggtt
     6361 gtaccggaag aaatagcgtt tcttgggaaa aaaacaaaat catttatata taataaaatt
     6421 gaaaagaaag cgataagaag ctgctataag ttaatacatg tgactacagc tatgaaggag
     6481 ttttatgaaa gaaaatataa tctaaattta gcttcaagat ctattgtact gcctattttc
     6541 gaaaaaacca cgatcaatcc taaccatagc aagtgggagt ctaatacttt tgagactatt
     6601 tatgcaggtg gcatgcaagc ttggcagaat attgacttga tgattaaagt aactaaggga
     6661 ggagatacca gaaatataaa gtttaacttt ttctttccac aggaattaat ttcagatttc
     6721 aaacttaaat tgggtgaccg tttagatagt agaactatca tggtggactc tttaccaaaa
     6781 gaagatgtca ttaaagttat gaccagatgt catctggggt ttgttttaag agatgatata
     6841 gtagttaata gagtggcttg cccaacaaaa ctaattgaat atctagaatg tggtgttgtt
     6901 cctattatta aatctcctga cattggggac tttaatacac taggttactc atttattaga
     6961 gtagaagaac taaatggttc tttaagtatg gatgatttac gtaaaaaagt tgaaaataat
     7021 tataaagtat tagctcattt tcagtcatta acggaacact ctaaatcgat tctaataaat
     7081 atatttaaaa atgcaaacga aaggttagag aataaagtga tgccatgatg aaggatacgc
     7141 gttatcagca ctgtagggtt atatactagt tattgatggc gcttgattta tcaataacag
     7201 aagatcagaa tgcctgctat gaaaatcttc atcactgtcc aataaaaagt taaacttgaa
     7261 ggcctgtatg atttcagctg cggcaaaaag gcttgagaac gtaaaactat tctacttgct
     7321 tctgaaggcc gtatttctgg cttgacgttc agactttgcc ctgtagtaga tgaccgtcga
     7381 ttatcaagtc atctagtttc tctgcagagg taaggatagt atgtctctgt ttttatcata
     7441 aaagttgagg ggcaggatat tttctgataa agcaaaaata ttgtgctaat taattctttt
     7501 aaaaaaagag ttactaaagt tgtttattgt gaaatttatt aatccccaaa ggatattaaa
     7561 catatccaaa taatatagca ggagaatttt tttgaactat ttgtaatgat ggttttataa
     7621 gttaataaaa aatttacttt agataaatat cacgtgagaa atgtattatg aatatattat
     7681 ctatcataag tgactaaaat gccagtaaaa actaacaact ttctttattt cataatggtc
     7741 ataagtgcta ccatttttgc tgttaaaata gtgccttatt cgaatgacta tcaggcatat
     7801 attgatttat tcaaatatac aattcaagat ccttcttacg agagaatgga aattggcttt
     7861 aaaaacctta ttggtttttc aaaatttctt gatttgaatt ttgatgtatt atggttttta
     7921 gttgctttta tttctttgtc gctaaaatgt tatgtattaa aatcctatga ttcagatatc
     7981 cttgtattat ttttgttgta ctttttgtac gctatatcat tattagcttt acacgaaacc
     8041 acacagatac gagcggctat tgcaattgct ttaggtatag caggctttcg atgtacgaat
     8101 aaatttgttg gtatctgttt aatcctttct tctgtattat ttcactattc agcaatttta
     8161 tttattattt tgtatacttt gagctttata gttaaaccgt ataagttcac atggttaata
     8221 gttgttgtta ctatggcgat actaataccc ttgcttctgg aacaatactc agatccatta
     8281 attagtatta atccattatt ttcattatat ttagaaaact ctgataatgc caaggtaaat
     8341 aaattttctt ttactttaat tcttgctaca atattttttg taataaattt ttttattgga
     8401 agaaaaatta actattatag caataataat ttcatattta agcaatataa tcttttttct
     8461 tttctttatc tttctagcgt agtactttta tctgcgttgt ctttttcgcc agtcatttca
     8521 ataagattat atgagttatt ttcgttaagc ccttttatta ttatcgcatg cctttattct
     8581 aaaagtatga aatacgtttt ttattctaat ataaatttgc gcttgctaag aagagttttg
     8641 cttttaacat tatggctaat ctcagtgcat cgctttattg cttattactt tgttaatcca
     8701 atcattaaat tttaaattaa atgataaaaa ggaattataa cgtgtcctct aataatgttc
     8761 cgtatatagc cgcagttctt gtaacgttca acccagactt aaatattttc caggaagtaa
     8821 taaatactat atcatcacag gtgcaacatc ttattgttat cgataactgc tccaaaaaca
     8881 ggcttgatat aagcctgttt ttaaatggaa aagaaggagt ggttttatta cctcaaaaca
     8941 ataatatagg attagctgcg acacaaaata ttggcattca atatgttaaa gaaaatatta
     9001 atgcgaccca tgtaatttta ttcgatcagg atagtattat taaaccatat tttatttcaa
     9061 atttagtaaa tgaagaacta gggttaatta gtaaagggat taaagtaggt gcaattggac
     9121 ctagctttta tgatcccgac aataatcaag attatcctgc cactgtctat attggacctt
     9181 ttataaaacg cgttaaactt ggagacaatc cagttgaagc cacttttttg attgcttcgg
     9241 ggtgtttgat taatctgaat gtattaaaaa acgtaggtgg tatgcttgaa gagctattta
     9301 ttgattatat tgatgttgag tggtcattaa gagcaaagaa gttcggttac aggttattta
     9361 ttactcccaa agcatcaatg gcacacacta taggtgataa gagaatttct ttatttggac
     9421 gtactgtctc ttgtcacagt tcatttcgac gttattttct tgtacgaaat agtttcaaaa
     9481 tgctaaggtt gccttatata cctattggct ataaagttcg tgagactgta ttcaattttc
     9541 taagagttat aattggtcta gcgacaagtt cagataggaa aaagtttatt aaatatacac
     9601 tcgccgcttt taaagacggt ttttttggaa aatttggacc ttgtaagtat aatttttaaa
     9661 atgattaaaa ttgcacacat acaacttctt ccactattaa gtggtgtcca gcgagtttgt
     9721 cttgatgaat taattcgtct tgatgaaaat aaatttgata aatatctaat atgcaaagag
     9781 gaaggtcctt taactgttga agcaaaaaaa tatggcataa aatgtttaat ggtacgaaat
     9841 ctcgttagag agatttcgct aaaaaatgat ctaaaagcac tttggtcttt atggaaaatt
     9901 attaagcaat ataagtttga tattgttcac actcattcat ctaaaactgg agtgcttgga
     9961 cgagttgctg catggctaaa tcgtacgaac ctaatagttc atactgtaca tggcttctct
    10021 tttccaattg ctaaaaataa gcaacagaga atattatttt ggctaatgga gaagattggt
    10081 tctatgtgtg gagatattat aatttgttta catgaagatg atgctaaaat agctcagtca
    10141 attcttaaga tcaataagca taaaatatgt ataataagta atggcgtcga tatcgaaaag
    10201 tttaaacctt atgatgaggg taggaaattt ctttgtcggg aaaatattaa aggtattgat
    10261 agtgacgata taataattgg aatgatagga cgtctttggc cacaaaaaaa tccaatatgt
    10321 ttactgcgtg cagttgcgga aataataaag agtaataaaa aagtaaagtg tttttttatt
    10381 ggtgacggtg agttatatgg agaaatggcc cacttcatta aatctaatca tcttagtaat
    10441 aacgtgcagt tatttgggtg gcgtaatgat acgcatactt ttcttaatgc aatggatatt
    10501 tttgttttgc catccctttg ggaagggatg cctttagcca ttctggaagc caaaagttgt
    10561 ggccttccct gtgttgtctc caatatacaa gggaatcgta gtattattga cggtgtcgag
    10621 gatgggttgt tattcgattt ggatttgagt tggcatgact tatatgaaaa attacaattg
    10681 cttattggag attctcagtt aaggagtatt atcggtaaaa aagcccgatt gagtataata
    10741 aatcattata atattgcttc cagaattaag aaaatcgaga ggatgtatct gaggaaaatt
    10801 aaaaaacatt ctcacgttaa ttcttaaaag atgtattctt tcataagcta aagtagcata
    10861 attttatggt ttgccgtaat taatatttag cctcgactta gatgtgattt ttattttaga
    10921 cattatagtg gggcagagat aaaatatgat cagttcgctg aattaatctt attaagaact
    10981 caatttttta ttgaagactc aaaattatat aaattatact gtcattaatt actattttta
    11041 agttattatt taagggtttc aaaccgtgtc tacctggcgc ggtgaccaca cctgacagga
    11101 gtatgtaatg gccaagcaac agatcggcgt cgtcggtatg gcagtg
//
