LOCUS       JX975346               13355 bp    DNA     linear   BCT 27-AUG-2013
DEFINITION  Salmonella enterica strain G1462 O antigen gene cluster, complete
            sequence.
ACCESSION   JX975346
VERSION     JX975346.1
KEYWORDS    .
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13355)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Senchenkova,S.N.,
            Reeves,P.R. and Wang,L.
  TITLE     Structural diversity in Salmonella O antigens and its genetic basis
  JOURNAL   FEMS Microbiol. Rev. (2013) In press
   PUBMED   23848592
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13355)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Reeves,P.R. and
            Wang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-OCT-2012) TEDA School of Biological Sciences and
            Biotechnology, Nankai University, 23 Hongda Street, TEDA, Tianjin
            300457, P.R. China
COMMENT     ##Assembly-Data-START##
            Sequencing Technology :: Sanger dideoxy sequencing
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..13355
                     /organism="Salmonella enterica"
                     /mol_type="genomic DNA"
                     /strain="G1462"
                     /db_xref="taxon:28901"
                     /note="serogroup: O47"
     misc_feature    1..13355
                     /note="O antigen gene cluster"
     gene            173..1531
                     /gene="rib"
     CDS             173..1531
                     /gene="rib"
                     /codon_start=1
                     /transl_table=11
                     /product="Rib"
                     /protein_id="AFW04864.1"
                     /translation="MKNIAVILASGTGSRFGARIPKQFVKLAGKPVIQYTLQAFQIAK
                     RIDEIIIVTNEEYVDFVTELTVENNYNKVKKIINGGKERYESSWAALQSIELAECNVI
                     FHDAVRPFVSQRIIDDCIEGLNSYNAVDVVVDPTDTIVKIKNKEIMSIPDRRFLARGQ
                     TPQGFKKTLIEKAYVNFLKEEHRIASDDCGIFLKYMPNEPIGIIKGDESNFKITHQQD
                     IYLADNLIKDGLLELASESSDKIERVISEKVIVIFGGNSGIGKSLLAKTKSLDGNVYS
                     FSRSNGIDISVSLDVRNALQQVFEKEGRIDFIINTAAVLIKKPINFMSEEEIEESCNT
                     NYLGAINIAREGYKYLKQTKGMLINFTSSSFTRGRATYSLYSSSKAAVVNLTQALSEE
                     WLNLGIKVNCINPERTDTPMRRVNFGIEPPESLLTSEQVADMTLSIMSSDYTGQVVAV
                     KK"
     gene            1536..2756
                     /gene="wzx"
     CDS             1536..2756
                     /gene="wzx"
                     /note="Wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AFW04865.1"
                     /translation="MSLRKNISGLAVAQIFSYIVPLLQFPYLSRIVGDSFLGAIIFML
                     SISQMAMVLTDYGFDLSIGEQIARGRKNKKWLSVFYCQVAVIKTILLIFAFMLIIGAL
                     NISGHAFPIQLTLGLIICVMFNAYNPYWIFQGLEKIYIYSALVIISRFFGLMLVYLII
                     KIPEDYIYYSWILAFQAGAITLISHYFVIKWGIQIRRIKVKNIIKQLKYSFDFFLSRA
                     CVSLYSSGCSVFLATFGGSLNQVAIYGVAEQLYKAGVQVFSPIISALTPYMVRTKNYI
                     VFNKILLGCLVVTVVGICTGFLAGNQIITLIYGYGYQESKSVLNIFMIIIVASVFGML
                     FGYPALLPLGLGKVANYSVIVSGILQILMFSILYIGIFPITAISVCITYLICDWFMFF
                     IRLYAFVKYRKFNG"
     gene            2749..3567
                     /gene="wdbI"
     CDS             2749..3567
                     /gene="wdbI"
                     /note="WdbI"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04866.1"
                     /translation="MDKTLRAAQLKMLVILDEIDRICRLNNIDYWLDAGTLLGAKRHG
                     GFIPWDDDIDICMKREDYNKFISVCNIHLDKNNFFLQTAYSDKYYVDYNTPCKVRMNK
                     TKIIEKNEMEYNYYDMRSHHGLFVDIFPYDKYSSNVYIRKYIERFMAQLFKIKVISSY
                     SKLPFLKNIMTKILSRVISKKILLSTVYYLSKKMSKRKSNYCLGAGIETPFFRAYYKE
                     GAIFPLKEIEFEGRMYKCPNDVDNYLNMMFGKDFMNIPPVSQRVWHYYSIDIDE"
     gene            3575..4669
                     /gene="wzy"
     CDS             3575..4669
                     /gene="wzy"
                     /note="Wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AFW04867.1"
                     /translation="MIEGYVVYNSIFLLALLFGFMKNYCLRKYFLLCLFLVLWVPLAT
                     RYGIGRDYFSYVDIYKNVLVTRDGIEVGFYYLNYLLAYFGFHYQSIFILTSFITVYLS
                     VKSFDREYTIVSIILFGVLVYLQAFSIVRQMLAVALCLYSCSLWNKGVKVKAIIFLML
                     APLFHYSAVIIFILAIISRCVKIDTFKCLAMLGLSLIFVFVFNGIDFIFSNPILLNSK
                     YGYYVTSAFNRPTEIGSGIGVAIALFLPFLIFMKASKIYKHNKNYNLMLLINLVYVVS
                     FVLSLKIYIFARFTDALSFVLILLIPAALKISNTRGLYYNCMLSVVILHIMLFEVNLK
                     ANTIAAGDMSNSGLGIMPYSNIINAHMLKY"
     gene            4676..5767
                     /gene="wdbJ"
     CDS             4676..5767
                     /gene="wdbJ"
                     /note="WdbJ"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04868.1"
                     /translation="MKKKILFITPLPPPVTGQSLACAELYNHLNNQNYDIEVINLSKQ
                     SFISGKGSLRRVLEIAKILFRILWAKKNYDLIYFTPAESKMGSFKDQLIYLFLFPNLN
                     KMYIHLHGGAGMRCLLGDNKKLIYKINKFFISRLAGVIVLGEALKNIYSGLIENNKIH
                     AVENFSQDYLFIKNSEFKIKHSDKKKLKVLFLSNLLPGKGYLELLESAKLLDKSQVEF
                     HFAGGFENEYDKDKFLKFIELQNNIFYHGIVSGDIKRKLLVEADIFCLPTYYPYEGQP
                     ISILEAYAAGCVVITTNHSGIFDIFEPNRNGLEVTKKSVSDLVEAITYFNKNRKEIHR
                     VSINNIVDARKKYRLRHHLNKIISVLMSK"
     gene            5781..6917
                     /gene="wbuX"
     CDS             5781..6917
                     /gene="wbuX"
                     /note="WbuX"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="AFW04869.1"
                     /translation="MNVYKICKRCIMDTSDPNISFDENGQCDYCLNFDKNIAPNWQTD
                     DTGFSKLSEISEAIKKDRGESDFDCIIGLSGGLDSSYAAYIAKEKMGLRPLLFHVDAG
                     WNTDQAVGNIEKLIEGLGLDLYTEVVNWEEMKDLQLSFLKSGIPDQDLVQDASFFSAL
                     YKFARQHRIKHVITGSNYSTECCREPEEWGGYLGIDTLLFNDIHKKFGTRQLKSFPLV
                     DVLVYKLFYQKILGMKVHHPLNLVPFNKKNAENELKEKFGWQPFQHKHHESRFTRFYE
                     DYWLPRRFGFEKRRAHFSSLIMTGQMTREEALERISKPEMDEHFLKQEFEYVAHKLGI
                     TVDELQQLFDMPKKTYRDYKNKRWLIGLGANVLRTLGLEKRYFR"
     gene            6914..7528
                     /gene="wbuY"
     CDS             6914..7528
                     /gene="wbuY"
                     /codon_start=1
                     /transl_table=11
                     /product="WbuY"
                     /protein_id="AFW04870.1"
                     /translation="MIKIIDYGIGNIQAFLNVYKRLGISADVARSVDDIESATHLVLP
                     GVGAFDQAMALFNDSGLRESIEKRVFEERIPIIGICVGMQMLATSSEEGNMSGLGWIP
                     GQVRTFSSNIASKNLPMPHMGWNSINKGTNTLLLKDFEETPSFYFLHSFYYECDDVDD
                     VLATAEYGHNFHCIVGRNNIFGIQCHPEKSHSSGYQLLKNFAEI"
     gene            7533..8321
                     /gene="wbuZ"
     CDS             7533..8321
                     /gene="wbuZ"
                     /codon_start=1
                     /transl_table=11
                     /product="WbuZ"
                     /protein_id="AFW04871.1"
                     /translation="MLRPRIIPCLLIHDSGLVKTINFKSPKYVGDPINAVKIFNEKEA
                     DELMVLDIDATSKGREPDYDLIKKLAAECRMPLCYGGGVTTAAQAAKIISLGVEKVSI
                     STAAVENPNLVRELAEAVGKQSVVVVLDIIKRTGLFSKGYELSTRNNTRTHKIDPISF
                     AQEMAGLGAGEIVINYIDNDGVMNGYDIGYSSTIKSHVNVPVTFLGGAGSYEHLTELI
                     DQCGIVGAAAGSLFVFKGKYRAVLISYPTPKQKDMICNGSMKNF"
     gene            8331..9368
                     /gene="fnlA"
     CDS             8331..9368
                     /gene="fnlA"
                     /note="FnlA"
                     /codon_start=1
                     /transl_table=11
                     /product="4,6-dehydratase, 3- and 5-epimerase"
                     /protein_id="AFW04872.1"
                     /translation="MMFKDKTLLITGGTGSFGNAVLNRFLSTDIKEIRIFSRDEKKQD
                     DMRKKYNNQKLKFYIGDVRDYRSILNATRGVDFIYHAAALKQVPSCEFHPMEAVKTNV
                     LGTENVLEAAIANEVKRVVCLSTDKAVYPINAMGISKAMMEKVMVAKSRNVNSNKTVI
                     CGTRYGNVMASRGSVIPLFVDLIKAGRPLTITDPNMTRFMMTLEDAVDLVLYAFEHGN
                     NGDIFVQKAPAATIDTLAIALKELLNVERHPVNVIGTRHGEKLYEALLSREEMIAAID
                     MGDYYRVPPDLRDLNYGKYVEQGDSRISVVEDYNSHNTQRLDVEGMKALLLKLPFIRA
                     LCAGENYDLEA"
     gene            9370..10473
                     /gene="fnlB"
     CDS             9370..10473
                     /gene="fnlB"
                     /note="FnlB"
                     /codon_start=1
                     /transl_table=11
                     /product="reductase"
                     /protein_id="AFW04873.1"
                     /translation="MKILITGADGFIGRNLCLRLQEKGDVDLIKIDRDSSTIELEIGL
                     QEADFIYHLAGINRPKNIEEFIEGNRNLTQQIVDFLLVNQKKTPIMISSSIQAGLDNA
                     YGQSKAAAEKQIERYAAKSGATYFIYRYPNVFGKWCKPNYNSFVATFCHNIANDVDIT
                     INDPAASVSLVYIDDVCTHALKLLTGTVDSGYKDVAPIYSTTVGEVAELIYRFKESRS
                     TLITEAVGTGFTRALYSTWLSYLPTDKFTYTVPFNGDSRGIFCEMLKTPSSGQFSFFT
                     AHPGITRGGHYHHTKNEKFLVIRGQARFKFEHVITGERYELNVSCDEFKIVETVPGWT
                     HDITNIGNDELVVMLWANEIFNRDEPDTIARAL"
     gene            10473..11603
                     /gene="fnlC"
     CDS             10473..11603
                     /gene="fnlC"
                     /note="FnlC"
                     /codon_start=1
                     /transl_table=11
                     /product="C-2 epimerase"
                     /protein_id="AFW04874.1"
                     /translation="MKKLKIMTVVGTRPEIIRLSRVLAKLDEHCEHILVHTGQNYDYE
                     LNEVFFNDLGVRKPDYFLNAAGKNAAATIGQVIIKVDEVLESEKPEAMLVLGDTNSCI
                     SAIPAKRRKVPIFHMEAGNRCFDQRVPEETNRRIVDHTADINMTYSDIAREYLLAEGI
                     AADRIIKTGSPMFEVLSYYMPQIDGSDVLSRLNLRAGEFFVVSAHREENVDSPKQLVK
                     LAKILNTIAEKYNLPVIVSTHPRTRNRINEQGIEFHPNINLLKPLGFHDYNHLQKNSR
                     AVLSDSGTITEESSIMNFPAVNIREAHERPEGFEEASVMMVGLECERVLQALEILATQ
                     PRGATRLLRQVSDYSMPNVSDKVVRIVHSYIDYVKRVVWKEY"
     gene            11603..12814
                     /gene="wbuB"
     CDS             11603..12814
                     /gene="wbuB"
                     /note="WbuB"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04875.1"
                     /translation="MKLALIIDDYLPDSTRVGAKMFHELAQEFIQRGHDVTVIYPDTS
                     LQEKVLFDSFQGVKTWRFKSGPLKDVSKIQRAINETLLSYRAWNAIKNQIKEETFDGV
                     VYYSPSIFWGHLVKKIKTRCQCPAYLILRDMFPQWVIDAGMLKAGSPIEFYFRFFERS
                     SYRQANRIGLMSEKNLDIFRITHRGYPCEVLRNWASLTPTILSQDYVPLRKRLGLEDK
                     VIFFYGGNIGHAQDMANLMRLTRSMAEHPQAHFLFIGQGDEVELINSLASEWGLSNFT
                     YLASVDQDEFKLILSEMDIGLFSLSARHSSHNFPGKLLGYMVQSLPILGSVNAGNDLL
                     DIVNQNNAGLIHINGEDDKLYHSALLLLQDINVRRKLGMGSNTLLKEQFSVESAAQTI
                     EMRLEACNAIN"
     gene            12801..13199
                     /gene="wbuC"
     CDS             12801..13199
                     /gene="wbuC"
                     /codon_start=1
                     /transl_table=11
                     /product="WbuC"
                     /protein_id="AFW04876.1"
                     /translation="MRLIDNDQLESLYKQAAQSDRLRAHLLLHRSHQEKVQRLLIALV
                     KGSYVDPHYHELPHQWEMFIVMAGQLQVCLHGKDGKVIKQFVVGDDTGISVVEFSPGD
                     IHSVLCMSPRALMLEVKEGPFDPSFSKAFI"
BASE COUNT     4171 a   2099 c   2772 g   4313 t
ORIGIN
        1 attggtagct gtaagccaag ggcggtagcg tgtgtaaact ctaacggagt agataaaatg
       61 tggacgcgta gtattgatat attttgtttc acaagagaat ttttatttgg cgatatatat
      121 cgtatgggtt tttaaactat atcaatactt atactacaat ttgagaggct atatgaagaa
      181 tattgcagta attctggcat ccggtactgg aagtagattt ggcgcaagaa tacctaaaca
      241 gtttgttaag cttgcaggaa agcctgtaat tcaatataca ttacaagcat ttcaaattgc
      301 aaagagaata gatgaaatta tcattgttac aaatgaagag tatgttgatt ttgttactga
      361 gttgactgta gaaaataatt ataataaagt taaaaaaatt attaatggcg gaaaggagag
      421 atatgagtct tcatgggctg ctctgcagag tattgaatta gcagaatgta atgttatttt
      481 tcatgacgcc gtcagaccat ttgtttcaca aagaattata gatgactgca ttgaggggct
      541 aaatagttat aatgcagtcg atgttgtagt agatcctact gatactattg taaaaattaa
      601 aaataaagag atcatgtcca ttcctgatag acggttcttg gctagagggc aaacacctca
      661 agggtttaaa aaaacgttaa tagagaaagc gtatgtcaat tttttgaaag aagagcaccg
      721 aattgcttca gatgattgtg gtatattttt aaaatatatg ccaaatgaac caattggaat
      781 tattaaggga gatgaatcta atttcaagat cactcaccaa caagatatat atcttgctga
      841 taatttaata aaagatggtt tattagagtt ggcttctgaa agtagtgata aaatagaacg
      901 ggtcatatct gaaaaagtaa ttgtaatatt tggtgggaat agcggcattg ggaagtctct
      961 tttagctaaa actaagtcgc ttgacggaaa tgtttattct tttagtcgta gtaatggtat
     1021 cgatattagt gtttctctgg atgttagaaa tgcgttgcag caagtgtttg agaaagaagg
     1081 gagaattgat tttataatta atacagctgc agtactgatt aaaaagccaa tcaattttat
     1141 gtcggaagaa gaaatagaag aaagttgtaa tactaattat ttaggtgcaa ttaatattgc
     1201 acgagaagga tataaatact taaagcaaac aaaaggaatg ttaattaatt ttacctccag
     1261 ttcatttact cgaggaaggg ctacatatag cctctattca tcttctaaag ctgctgttgt
     1321 gaatttaact caagctttat cggaagagtg gttaaattta ggtattaaag ttaactgtat
     1381 taatccggaa cgtacagata ctccaatgag aagagttaac tttggtattg aaccaccaga
     1441 gtcattatta acctcggagc aggttgcaga tatgacattg tcaattatgt cttcggatta
     1501 tacaggacaa gttgtagctg tgaagaaata gtcaaatgtc tttacggaaa aatataagtg
     1561 ggctagcagt agctcaaatc tttagttaca tagtgcctct gttgcaattc ccctatttga
     1621 gtcgaatcgt aggggattct tttttaggtg ctattatttt catgctgtca atatctcaaa
     1681 tggcaatggt attgactgac tatggttttg atttatcaat tggagaacaa atagctcgcg
     1741 gaagaaaaaa taaaaagtgg ctgagtgtct tttattgtca ggtagctgta ataaaaacta
     1801 ttctgctaat attcgcattt atgctgataa ttggagcgct taatatatca ggacatgctt
     1861 ttccaatcca gttaactttg ggattaatta tatgtgttat gtttaacgca tataatccat
     1921 actggatatt ccaggggtta gagaaaatat atatatatag tgctttagtt atcatttcaa
     1981 gattctttgg gctaatgcta gtatatctca ttattaagat tcctgaagat tatatttatt
     2041 actcttggat actggcattt caggctgggg ccataaccct gattagtcac tatttcgtga
     2101 taaaatgggg gattcagatt agacgcatca aagtaaaaaa tatcattaag caattaaagt
     2161 atagttttga ttttttctta tctagagcct gtgtttcatt atattcgtct ggttgcagtg
     2221 tcttcttggc aacctttggt ggtagtttga atcaagtcgc aatttatggt gttgcagaac
     2281 aattatacaa agcaggcgtc caggtattta gtcctattat ttcagcctta acaccttata
     2341 tggtaagaac aaaaaactac atagttttta ataaaatatt attaggttgc ttggtggtta
     2401 cagtcgttgg tatatgtact ggatttctcg caggtaatca aattatcaca ttaatttatg
     2461 gttatggata tcaggagtca aaatctgtac ttaatatttt catgattata attgttgcaa
     2521 gcgtttttgg tatgctcttt ggttatccag cactattacc tctggggttg ggtaaagtag
     2581 caaactatag tgtaattgtc tctggcatat tacaaatatt aatgtttagc attttatata
     2641 ttggcatatt cccaataacg gcaattagtg tatgcattac ttaccttatt tgtgattggt
     2701 ttatgttttt tattaggctt tatgcttttg taaaatacag gaaatttaat ggataaaaca
     2761 ttgcgtgcag cacagctaaa aatgttagtt atactcgatg agattgatcg tatatgcagg
     2821 ctaaataata tagattattg gctggatgct gggacattat taggagcgaa acggcatggc
     2881 ggatttattc catgggatga tgatatagac atttgtatga aaagagagga ttataataaa
     2941 tttatttctg tgtgcaatat tcatcttgat aaaaataact tttttctaca aacagcgtac
     3001 tctgataaat actatgtaga ttataatacg ccatgcaaag taagaatgaa taaaacaaaa
     3061 ataatagaaa aaaatgaaat ggaatataat tattatgata tgagatctca tcatgggtta
     3121 tttgtggata tatttccata tgataagtat tcttcaaatg tatatatcag aaaatatatt
     3181 gaacgcttta tggctcaact atttaaaatc aaagttattt ccagttactc aaagctgcca
     3241 ttcttaaaga atataatgac aaaaatttta agtcgcgtca ttagcaaaaa aatattatta
     3301 agcactgttt attatctaag caagaaaatg agtaaaagga aatcaaacta ttgtttgggg
     3361 gccggaattg aaacaccatt ctttagggcg tactacaaag aaggcgcaat atttccatta
     3421 aaagaaatag agtttgaagg aaggatgtat aagtgtccaa atgatgttga taattatcta
     3481 aacatgatgt ttggtaaaga ttttatgaat attcctccag tcagccaaag agtatggcac
     3541 tattatagca ttgatattga tgagtagggt ttaaatgatt gaaggatatg tagtatataa
     3601 tagtattttt cttcttgcct tactatttgg ctttatgaag aattactgtc ttcggaaata
     3661 ttttttatta tgcttattcc ttgtcttatg ggttccactt gccactcgtt atggcattgg
     3721 tcgtgactat tttagctatg ttgatattta taaaaatgtg ttagttacca gagatggtat
     3781 tgaagtaggt ttttattatc taaattatct gttggcatat tttggtttcc attatcaatc
     3841 tatatttata ttgacatctt ttattactgt ctatttaagt gttaaaagtt ttgatagaga
     3901 atatacaata gtatcaatta tattatttgg ggttttggtt tacttacagg cgtttagtat
     3961 tgttaggcaa atgcttgctg tagccttatg tctttatagc tgttcgttat ggaataaagg
     4021 tgttaaggtt aaagcaatta tttttcttat gctggcacct ttgtttcatt attctgctgt
     4081 aataatattt atattggcaa taattagcag atgtgttaaa atcgatacgt ttaaatgtct
     4141 tgctatgtta gggcttagcc ttatttttgt ttttgtattt aatgggatcg attttatatt
     4201 ttcaaatcct atactattaa atagtaagta tggatattat gtaacatcag cctttaacag
     4261 accgactgaa ataggttcag gcattggagt ggcaatagca ttatttcttc cattcttgat
     4321 ttttatgaaa gcatcaaaaa tatataaaca taataaaaat tataatctga tgctattaat
     4381 aaaccttgta tatgttgttt catttgtttt atctttgaaa atatatatat tcgccagatt
     4441 cactgatgcg ctatcctttg tcctgatatt acttatccct gctgctctta aaatatcaaa
     4501 tactagaggc ctatattata actgtatgtt atctgttgtt attcttcaca ttatgctatt
     4561 tgaagtaaat cttaaagcaa atacaattgc agctggagat atgtctaata gcgggcttgg
     4621 aatcatgccg tatagcaaca taataaacgc acatatgcta aaatactagg tatatatgaa
     4681 aaagaaaata ttatttataa ctccattacc accgccagtg acaggacaat cattagcttg
     4741 tgctgaactg tataaccatt taaataatca aaactatgat atagaagtaa taaatctttc
     4801 aaaacagtca ttcatatcag ggaaaggctc gctgcgaaga gttctggaaa tagcaaaaat
     4861 tctttttaga atattatggg caaaaaagaa ttatgaccta atatacttta caccagctga
     4921 atcaaaaatg ggaagtttca aagatcagtt aatatatctt tttttatttc ctaatttaaa
     4981 taaaatgtat atccatttac atggtggagc tgggatgaga tgtttgctgg gggataataa
     5041 aaaattaata tataagataa ataaattttt tatttccaga cttgcagggg tgattgtatt
     5101 aggcgaagct ttaaaaaata tttactctgg attaattgaa aataataaaa tacatgcagt
     5161 cgaaaatttt tctcaagatt atttgtttat taaaaatagc gagtttaaaa taaagcactc
     5221 tgataagaag aaattaaaag tactttttct tagtaatcta cttcccggca aaggctatct
     5281 tgaattatta gagtctgcaa aacttcttga taaatcacag gtggagtttc attttgctgg
     5341 tggctttgaa aatgaatacg ataaagacaa atttctaaaa tttattgagt tacaaaataa
     5401 tattttttac catggaattg ttagtggaga tataaaacgg aaattattag ttgaagccga
     5461 tattttttgt ttacctacat attacccata tgagggtcaa cctattagta tccttgaggc
     5521 ctatgcagca ggatgtgttg ttatcacaac caatcatagt ggtattttcg atatttttga
     5581 acctaacagg aacggattag aagttactaa aaagagtgtt tctgatttag ttgaagcgat
     5641 aacttatttt aataaaaata gaaaagaaat tcatagagtt tcaatcaata atatagttga
     5701 tgcaaggaaa aaatatagac ttaggcatca tttaaataaa ataatatcgg tattaatgag
     5761 taagtgaggt ggtaattctg atgaacgttt ataaaatttg taagagatgt attatggata
     5821 catccgatcc caatatttcc tttgatgaga atggacaatg tgattattgt ttaaattttg
     5881 ataaaaatat agcaccaaac tggcaaactg atgatacagg tttttcaaag ttatccgaaa
     5941 tctcagaggc aatcaaaaag gaccgtggcg aatcagattt tgattgtatt attggtttgt
     6001 caggaggatt agacagctcc tatgctgcat atattgcgaa ggaaaaaatg ggattaaggc
     6061 ctcttttatt ccatgttgat gcaggatgga atacagatca agctgtgggc aatattgaaa
     6121 aacttattga agggcttggt ttagacctct atacagaagt tgttaattgg gaggaaatga
     6181 aagatttaca gctttccttt ttaaaatctg gtattcctga tcaggattta gttcaggatg
     6241 catccttttt ttctgcctta tataaatttg ctcgccaaca tagaatcaag catgttatca
     6301 caggttctaa ttattcgaca gaatgttgtc gtgagccaga ggaatggggc gggtatttag
     6361 gtatcgatac cttattattt aatgatattc ataaaaaatt tggtacgcga cagttaaaat
     6421 catttccatt agttgatgta ttagtataca aactctttta ccagaaaatt cttggtatga
     6481 aagtgcatca cccactgaac ttagttcctt ttaataaaaa aaatgcagaa aatgaactga
     6541 aagagaaatt tggttggcaa ccctttcagc ataaacatca tgaatctcgt tttactcgtt
     6601 tctatgaaga ttattggctg ccacgtagat ttggtttcga gaaacgaaga gcgcattttt
     6661 caagtttaat tatgaccggt caaatgacca gggaagaagc attagagaga atttcaaaac
     6721 ctgaaatgga tgaacatttt cttaaacagg aatttgagta tgtagcgcat aaactcggta
     6781 ttactgtaga tgaattgcaa caactttttg atatgcctaa aaaaacctac agagattaca
     6841 aaaataaacg ttggctaata ggtcttggtg caaacgtgct gcgtactctt ggattagaaa
     6901 aaaggtattt tagatgatta aaatcattga ttatggcata ggaaatatac aagcgttcct
     6961 gaacgtatat aaacgacttg gtattagtgc ggatgttgct cgttccgttg atgacattga
     7021 aagtgctact catttagtat tgcctggcgt tggggctttt gatcaggcca tggcgctttt
     7081 taatgactca ggtttgcgtg aaagcattga aaaacgcgtt tttgaggagc gaatacccat
     7141 tattggtatt tgtgtaggca tgcagatgct agccacctca agtgaagagg gaaacatgtc
     7201 tggtttaggc tggattcctg gtcaggttcg cacattcagc agcaatatcg cttcaaaaaa
     7261 tcttccaatg ccacatatgg gatggaatag tataaataaa ggaacaaata cactattgct
     7321 gaaagatttt gaagaaacac cttcctttta tttcttacat tcattctatt acgaatgtga
     7381 cgatgtagat gatgtattgg caactgctga atatggtcat aattttcatt gcatcgttgg
     7441 aaggaataat atttttggca tccagtgcca tccagaaaaa agtcattctt caggttacca
     7501 actattgaaa aattttgcag agatctaata atatgcttag gccaagaatt ataccctgtt
     7561 tgcttatcca cgattctggt ttagtcaaaa caattaattt taagtcccct aagtatgtag
     7621 gcgacccaat taatgccgtc aaaattttta atgaaaaaga agctgacgaa ttgatggtcc
     7681 ttgatataga tgcaacatcc aaggggcgtg agcctgatta tgatctaatt aaaaaacttg
     7741 cggctgaatg ccgtatgcct ttgtgttatg gcggaggggt taccactgct gcccaggcag
     7801 ctaaaattat ctctcttggc gttgaaaagg tatcaataag tactgcggcg gttgaaaatc
     7861 cgaaccttgt ccgtgagttg gcagaagcag ttggtaaaca aagcgtagtt gtagttctgg
     7921 atattatcaa acgaacaggt cttttttcaa agggatatga gctttcaacg aggaataaca
     7981 ctcgtacgca taaaatcgat cctatctcat ttgctcaaga aatggctggc ttgggggcag
     8041 gggaaattgt tatcaattat atagataatg atggtgtcat gaatggttat gatattggat
     8101 actcttctac tataaaatct catgtgaacg ttcctgttac gtttctcggt ggtgcaggta
     8161 gttatgagca ccttaccgaa ttgattgacc aatgcggtat cgttggagca gcagctggga
     8221 gtctttttgt atttaaaggt aagtatagag cggtcttgat aagctatcct acgcctaaac
     8281 aaaaagatat gatttgtaat ggctcgatga agaattttta ataaggattt atgatgttta
     8341 aagataaaac actgctgatt acgggtggaa cagggtcttt tggtaatgct gtattgaatc
     8401 gctttctttc tacagatata aaagaaatcc gcattttctc tcgcgatgaa aaaaaacaag
     8461 atgatatgcg gaaaaaatat aataatcaga agttaaagtt ttatatcggt gatgtcagag
     8521 attatcgtag cattttgaat gcaactcgtg gtgttgattt tatttaccat gcagcggcgc
     8581 ttaagcaggt gccatcatgt gaattccatc caatggaagc tgttaaaact aatgtgctcg
     8641 gcacagagaa tgtactcgaa gctgctatcg ctaatgaagt aaaacgtgtt gtttgcttaa
     8701 gtactgacaa agcagtttat cctatcaatg ccatgggaat ttcaaaggca atgatggaga
     8761 aagtgatggt cgcaaaatca cgtaacgtaa atagtaataa aacggtgatc tgtggtacac
     8821 gctatggcaa cgtgatggct tcccgtggtt cggtgattcc tttatttgtg gatctcataa
     8881 aagcgggtag gccactgaca attaccgatc caaacatgac tcgctttatg atgactcttg
     8941 aagatgcagt tgatcttgta ctttatgcat ttgaacatgg taataatggt gatatcttcg
     9001 tacaaaaggc ccctgctgct acgattgata cattagcaat tgcactgaaa gaactcttga
     9061 acgttgagcg ccatccagtt aatgttatcg gtactcgcca tggcgagaag ttatatgaag
     9121 ctttacttag tcgcgaagag atgattgcag ctattgatat gggggattat taccgtgttc
     9181 caccagattt gcgtgatctt aattacggga aatatgtaga acagggtgat agccgtatct
     9241 cggttgttga agattataac tcccataata cacagcgact ggatgttgaa ggaatgaaag
     9301 ctctgcttct taaattaccg tttattcgcg cactgtgtgc aggtgaaaat tacgatctgg
     9361 aagcctgata tgaaaatcct gattactggt gctgatggtt ttattggacg taacttgtgc
     9421 ttgcgtcttc aggaaaaggg ggatgttgac cttattaaga ttgatcgtga ttcaagtact
     9481 attgagcttg aaataggcct gcaagaagct gattttattt atcatctcgc tggtatcaat
     9541 cgacctaaaa atattgaaga gtttattgaa ggcaacagaa atctgactca acagattgtt
     9601 gattttctgt tagtgaatca gaaaaaaact cctattatga ttagttcctc tatccaggca
     9661 gggctagata atgcgtatgg tcagagtaaa gcagcagctg aaaaacagat tgaacgttat
     9721 gcggcaaaaa gtggagctac atattttatc taccgatatc caaatgtttt cggaaaatgg
     9781 tgcaaaccaa actataactc gttcgtagct actttttgtc ataacattgc caatgatgtt
     9841 gacattacca tcaatgaccc agcggcatcg gtaagtctgg tttacatcga tgacgtttgt
     9901 actcatgcgt taaagcttct tacaggaacg gttgatagcg gatataaaga cgttgctccg
     9961 atttattcaa caacagttgg ggaggtagca gagttaattt atcgcttcaa agaaagtcgt
    10021 tctactctta tcactgaagc tgttggcact ggattcactc gtgcattgta ttcgacgtgg
    10081 ttaagctatt tgcctaccga caagtttact tatacagtgc cattcaatgg tgatagccgt
    10141 ggtatctttt gtgaaatgtt aaaaacaccg tcatcggggc agttttcctt tttcacagca
    10201 catccaggga tcacgcgagg tgggcattat caccacacta aaaatgaaaa gtttctcgtc
    10261 attcgtgggc aggccagatt caaatttgag cacgttatta ccggtgagcg ttatgaacta
    10321 aacgtttcat gcgatgaatt taaaattgtt gaaacagttc ctggttggac acatgatatc
    10381 acgaatattg gcaatgatga attggtagtt atgctctggg caaacgaaat tttcaatcgt
    10441 gatgagcctg atactattgc gagagctcta taatgaaaaa attaaaaatt atgactgtgg
    10501 ttgggactcg tccggaaatt attcggttat cacgcgtttt ggctaaactt gatgagcatt
    10561 gcgagcatat acttgttcat actggtcaaa actacgatta tgaattaaat gaagtattct
    10621 ttaacgacct tggtgtccgc aagccagatt attttttaaa cgccgcaggg aaaaatgcag
    10681 ctgcgaccat tggacaggtt atcattaaag ttgatgaggt attagaatcc gaaaagcctg
    10741 aagcaatgtt ggtgctgggc gatacaaatt cctgtatttc agctatccct gccaagcgtc
    10801 gtaaggtgcc tattttccat atggaagctg ggaaccgttg cttcgatcag cgcgtacctg
    10861 aggaaactaa ccgacgcatt gtcgaccata ctgccgacat caatatgacc tatagcgata
    10921 ttgcacgtga atatctattg gctgaaggga tcgcagcgga tcggatcatt aaaaccggta
    10981 gtcctatgtt tgaggtactt tcttactaca tgccccaaat cgatggttca gatgttctct
    11041 ctcgcttgaa tctacgtgcc ggtgaatttt ttgttgtgag tgcgcatcga gaagaaaatg
    11101 tcgattctcc gaagcaactc gtcaagcttg caaagattct aaacactatt gctgaaaaat
    11161 ataatcttcc ggttatcgtt tctacacatc cgcggacgcg taatcgtatt aatgagcaag
    11221 ggattgaatt ccacccaaat attaatctac tgaagccgtt gggtttccac gattacaacc
    11281 acttgcagaa gaattctcgt gctgtattgt ccgacagcgg tacgatcaca gaagaatcat
    11341 ccatcatgaa ttttccagcg gtaaacattc gggaagctca tgagcgccca gagggctttg
    11401 aggaagcatc tgtcatgatg gtggggctag aatgcgaacg tgtacttcag gctttggaga
    11461 ttctggcaac gcagcctcgt ggagcgaccc gtcttttacg acaagtcagt gactacagta
    11521 tgccgaatgt atcggataaa gttgttagaa tcgttcactc ttatatagat tacgtcaaga
    11581 gagttgtctg gaaagaatat tgatgaaact tgctctaatc atagatgatt acctaccaga
    11641 tagtacccgt gttggcgcaa aaatgtttca tgaactggcc caagaattta ttcagcgtgg
    11701 gcatgatgtt acggtgattt atcctgatac tagtctgcaa gaaaaagttt tgtttgactc
    11761 gtttcagggg gttaaaacgt ggcgcttcaa aagcgggccc ctcaaggatg tgagcaaaat
    11821 tcagagagcc atcaatgaga cgcttttgtc gtatcgagca tggaatgcta tcaaaaacca
    11881 gataaaagaa gaaacctttg atggcgtggt ttattattca ccttccatat tttgggggca
    11941 tctggttaag aaaattaaaa cccgttgcca atgcccggct tatctcattt tgagggacat
    12001 gttccctcaa tgggtgattg atgcaggaat gctaaaagcg ggttccccaa ttgagtttta
    12061 ttttcgtttc ttcgaaagat catcctatcg tcaggcaaac cgtattgggc tcatgtctga
    12121 aaagaatctt gatatttttc ggataactca cagaggttat ccttgcgagg ttctacgtaa
    12181 ctgggcatca cttacgccga cgatattatc ccaggattat gtgccattgc gtaagcgtct
    12241 tggccttgaa gataaagtta ttttcttcta tggcggaaat ataggtcatg cccaggatat
    12301 ggcgaatctg atgcgtctta cgcgaagtat ggcagaacat ccgcaagctc attttctgtt
    12361 tattggtcag ggggacgaag tcgaattaat caactcttta gcttctgagt gggggctatc
    12421 gaattttacg tatttggcct ctgtggatca ggatgaattt aagctaattc tgtcggaaat
    12481 ggatataggc ctgttttcac tttccgccag acactcttcc cacaatttcc ctggtaagtt
    12541 attaggctac atggttcagt cgctacctat attaggtagc gtgaatgccg gaaatgattt
    12601 gcttgatatc gttaatcaaa ataatgcagg gctaatacat attaatggtg aagatgataa
    12661 gctttatcat tccgcactgt tattgcttca agatattaat gtacgacgta agcttgggat
    12721 gggctcgaat acattattga aagaacagtt ctctgttgag tctgctgcac agacgataga
    12781 aatgaggctg gaggcatgta atgcgattaa ttgataatga ccagctcgag tcattatata
    12841 aacaggcagc gcaatcagat cgcctgcgtg ctcacctttt gttgcatcgt tctcatcagg
    12901 agaaggtaca acgactgctt attgctttgg tcaaggggag ctatgtagat cctcactacc
    12961 atgaactacc tcatcagtgg gaaatgttta tcgtcatggc agggcagctt caggtctgct
    13021 tgcatggaaa agatggaaag gtcattaagc aatttgttgt cggagacgat accggaataa
    13081 gtgtagtgga gttttctcca ggggacatac atagcgtttt atgcatgtct ccacgggcac
    13141 ttatgttgga agtgaaagag ggaccttttg acccatcttt ttctaaagcg tttatttaat
    13201 gccggtctga aacgcaatct tccgctatct accgaggcca atcctgagtt aacatctaag
    13261 ccacatttca agccgcgctc tcgtcgcgcg gtgaccacac ctgacaggag tatgtaatgg
    13321 ccaagcaaca gatcggcgtc gtcggtatgg cagtg
//
